SAMN10230270
External Id
the Institute of Cardiovascular Medicine, Southwest Medical University
INSDC center name
2019-03-01T00:50:08.943Z
INSDC first public
2019-03-01T00:50:08.943Z
INSDC last update
SRS3931596
INSDC secondary accession
live
INSDC status
Model organism or animal
NCBI submission model
Model.organism.animal.1.0
NCBI submission package
SRS3931596
SRA accession
10 weeks
http://purl.obolibrary.org/obo/UO_0000034
age
C57BL6
http://www.ebi.ac.uk/efo/EFO_0004472
breed
It is known that stress can induce cardiovascular dysfunctions, but the underlying mechanisms are still not well elucidated. The present study aimed to test the hypothesis that alterations of DNA methylation in some cardiac genes may be a mechanism. A mouse model of chronic restraint stress (CRS) was used. Cardiac DNA methylation were sequenced respectively by representation bisulfite sequencing (RRBS).
description
WT
http://www.ebi.ac.uk/efo/EFO_0001103
genotype
Mus musculus
http://purl.obolibrary.org/obo/NCBITaxon_10090
organism
Fertile
phenotype
Genome DNA
http://www.ebi.ac.uk/efo/EFO_0008479
sample type
male
http://purl.obolibrary.org/obo/PATO_0000384
sex
musculus cardiacus
tissue
Model organism or animal sample from Mus musculus
title