characteristics.text: SAMN22072368
characteristics.characteristic: External Id
characteristics.text: Shanghai East hospital
characteristics.characteristic: INSDC center name
characteristics.text: 2022-03-31T00:50:57.083Z
characteristics.characteristic: INSDC first public
characteristics.text: 2022-03-31T00:50:57.083Z
characteristics.characteristic: INSDC last update
characteristics.text: SRS10473167
characteristics.characteristic: INSDC secondary accession
characteristics.text: live
characteristics.characteristic: INSDC status
characteristics.text: Human
characteristics.characteristic: NCBI submission model
characteristics.text: Human.1.0
characteristics.characteristic: NCBI submission package
characteristics.text: SRS10473167
characteristics.characteristic: SRA accession
characteristics.text: 55
characteristics.characteristic: age
characteristics.text: ATCC
characteristics.characteristic: biomaterial provider
characteristics.text: SiHa
characteristics.ontologyTerms: http://www.ebi.ac.uk/efo/EFO_0002379
characteristics.characteristic: cell line
characteristics.text: In order to characterize different scales of genome organization during cervical cancer development, we have used NHEK normal human epidermal keratinocyte and SiHa tumorigenic cervical cancer cells and performed genome-wide Hi-C, ChIP-seq as well as RNA-seq to identify structural variations, specifically TADs. We interpretated a correlation among chromatin structure, epigenetic landscape, gene expression, and HPV-LINC00393 integrated loci in SiHa cells. The results will help us to get a better insight into HPV-LINC00393 integration in cervical carcinogenesis.
characteristics.characteristic: description
characteristics.text: Japanese woman
characteristics.characteristic: isolate
characteristics.text: Homo sapiens
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/NCBITaxon_9606
characteristics.characteristic: organism
characteristics.text: female
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/PATO_0000383
characteristics.characteristic: sex
characteristics.text: cervical cancer
characteristics.ontologyTerms: http://www.ebi.ac.uk/efo/EFO_0001061
characteristics.characteristic: tissue
characteristics.text: HPV16-LINC00393 integration alters local 3D genome architecture in cervical cancer cells
characteristics.characteristic: title