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["SAMEA14388910","ABI-MS","2022-05-16T09:15:48.836Z","2018-02-01T00:00:00Z","2022-05-16T09:15:48.836Z",9606,[{"text":"Cohort of 147 patients (103 female, 44 male) diagnosed with MS","ontologyTerms":null,"unit":null,"characteristic":"description"},{"text":"multiple sclerosis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005301"],"unit":null,"characteristic":"disease state"},{"text":"147","ontologyTerms":null,"unit":null,"characteristic":"number of patients"},{"text":"Homo sapiens","ontologyTerms":["http://purl.obolibrary.org/obo/NCBITaxon_9606"],"unit":null,"characteristic":"organism"},{"text":"RNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C812"],"unit":null,"characteristic":"organism part"},{"text":"DNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C449"],"unit":null,"characteristic":"organism part"},{"text":"plasma","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C13356"],"unit":null,"characteristic":"organism part"},{"text":"PBMCs","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C12954"],"unit":null,"characteristic":"organism part"},{"text":"ABIRISK","ontologyTerms":["http://www.abirisk.eu/"],"unit":null,"characteristic":"project"},{"text":"Patients with MS or Clinically Isolated Syndrome (CIS) diagnosis according to McDonald criteria and who were prescribed IFN-beta-1a intramuscularly (IM), IFN-beta-1a subcutaneously (SC), or IFN-beta-1b SC (original product or biosimilar) were recruited from January 30, 2014 to January 22, 2016. Patients who were not naive to IFN-beta were excluded.","ontologyTerms":null,"unit":null,"characteristic":"study description"}],null,null,null,[{"url":"https://datacatalog.elixir-luxembourg.org/e/study/91f1a748-c48e-11ec-9b1d-acde48001122","duo":[]}],{"self":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388910"},"curationLinks":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388910/curationlinks"},"samples":null,"curationLink":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388910/curationlinks/{hash}"}}]
["SAMEA14388922","ABI-MS","2022-05-16T09:22:34.533Z","2018-02-01T00:00:00Z","2022-05-16T09:22:34.533Z",9606,[{"text":"Cohort of 147 patients (103 female, 44 male) diagnosed with MS","ontologyTerms":null,"unit":null,"characteristic":"description"},{"text":"multiple sclerosis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005301"],"unit":null,"characteristic":"disease state"},{"text":"147","ontologyTerms":null,"unit":null,"characteristic":"number of patients"},{"text":"Homo sapiens","ontologyTerms":["http://purl.obolibrary.org/obo/NCBITaxon_9606"],"unit":null,"characteristic":"organism"},{"text":"RNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C812"],"unit":null,"characteristic":"organism part"},{"text":"DNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C449"],"unit":null,"characteristic":"organism part"},{"text":"plasma","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C13356"],"unit":null,"characteristic":"organism part"},{"text":"PBMCs","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C12954"],"unit":null,"characteristic":"organism part"},{"text":"ABIRISK","ontologyTerms":["http://www.abirisk.eu/"],"unit":null,"characteristic":"project"},{"text":"Patients with MS or Clinically Isolated Syndrome (CIS) diagnosis according to McDonald criteria and who were prescribed IFN-beta-1a intramuscularly (IM), IFN-beta-1a subcutaneously (SC), or IFN-beta-1b SC (original product or biosimilar) were recruited from January 30, 2014 to January 22, 2016. Patients who were not naive to IFN-beta were excluded.","ontologyTerms":null,"unit":null,"characteristic":"study description"}],null,null,null,[{"url":"https://datacatalog.elixir-luxembourg.org/e/study/91f1a748-c48e-11ec-9b1d-acde48001122","duo":[]}],{"self":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388922"},"curationLinks":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388922/curationlinks"},"samples":null,"curationLink":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388922/curationlinks/{hash}"}}]
["SAMEA14388964","ABI-RA","2022-05-16T09:45:36.981Z","2018-02-01T00:00:00Z","2022-05-16T09:45:36.981Z",9606,[{"text":"Cohort of 229 patients (176 female, 53 male) diagnosed with RA","ontologyTerms":null,"unit":null,"characteristic":"description"},{"text":"juvenile idiopathic arthritis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0011429"],"unit":null,"characteristic":"disease state"},{"text":"rheumatoid arthritis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0008383"],"unit":null,"characteristic":"disease state"},{"text":"229","ontologyTerms":null,"unit":null,"characteristic":"number of patients"},{"text":"Homo sapiens","ontologyTerms":["http://purl.obolibrary.org/obo/NCBITaxon_9606"],"unit":null,"characteristic":"organism"},{"text":"RNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C812"],"unit":null,"characteristic":"organism part"},{"text":"DNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C449"],"unit":null,"characteristic":"organism part"},{"text":"plasma","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C13356"],"unit":null,"characteristic":"organism part"},{"text":"PBMCs","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C12954"],"unit":null,"characteristic":"organism part"},{"text":"ABIRISK","ontologyTerms":["http://www.abirisk.eu/"],"unit":null,"characteristic":"project"},{"text":"Patients with RA diagnosis according to 2010 ACR/EULAR criteria and who were prescribed for the first time a BP among the TNF inhibitors adalimumab, infliximab (original product or biosimilar), etanercept, the anti-CD20 antibody rituximab, or the anti-IL6R antibody tocilizumab (administered SC or intravenously) as first-line or second-line therapy were recruited from March 3, 2014 to June 21, 2016. Patients who were not naive for the biotherapy they were given in the study were excluded.","ontologyTerms":null,"unit":null,"characteristic":"study description"}],null,null,null,[{"url":"https://datacatalog.elixir-luxembourg.org/e/study/b4c2e822-c48e-11ec-9b1d-acde48001122","duo":[]}],{"self":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388964"},"curationLinks":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388964/curationlinks"},"samples":null,"curationLink":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388964/curationlinks/{hash}"}}]
["SAMEA14388965","ABI-IBD","2022-05-16T09:47:31.318Z","2018-02-01T00:00:00Z","2022-05-16T09:47:31.318Z",9606,[{"text":"Cohort of 184 patients (89 female, 95 male) diagnosed with IBD","ontologyTerms":null,"unit":null,"characteristic":"description"},{"text":"Crohn's disease","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005011"],"unit":null,"characteristic":"disease state"},{"text":"ulcerative colitis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005101"],"unit":null,"characteristic":"disease state"},{"text":"inflammatory bowel disease","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005265"],"unit":null,"characteristic":"disease state"},{"text":"184","ontologyTerms":null,"unit":null,"characteristic":"number of patients"},{"text":"Homo sapiens","ontologyTerms":["http://purl.obolibrary.org/obo/NCBITaxon_9606"],"unit":null,"characteristic":"organism"},{"text":"RNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C812"],"unit":null,"characteristic":"organism part"},{"text":"DNA","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C449"],"unit":null,"characteristic":"organism part"},{"text":"plasma","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C13356"],"unit":null,"characteristic":"organism part"},{"text":"PBMCs","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C12954"],"unit":null,"characteristic":"organism part"},{"text":"ABIRISK","ontologyTerms":["http://www.abirisk.eu/"],"unit":null,"characteristic":"project"},{"text":"Patients with Crohn’s disease or ulcerative colitis diagnosis according to ECCO guidelines and who were prescribed adalimumab or infliximab (original product or biosimilar) were recruited from September 11, 2013 to February 15, 2016. Patients who were not naive to TNF inhibitor therapy or who were treated with corticoids more than 30 mg/day over the last 15 days were excluded.","ontologyTerms":null,"unit":null,"characteristic":"study description"}],null,null,null,[{"url":"https://datacatalog.elixir-luxembourg.org/e/study/b4c2ea0c-c48e-11ec-9b1d-acde48001122","duo":[]}],{"self":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388965"},"curationLinks":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388965/curationlinks"},"samples":null,"curationLink":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14388965/curationlinks/{hash}"}}]
["SAMEA14391556","APPROACH source cohorts","2022-05-16T10:25:38.857Z","2017-09-05T00:00:00Z","2022-05-16T10:25:38.857Z",9606,[{"text":"Collection of 5 existing European OA cohorts used to identify subjects for a new longitudinal cohort via machine learning models trained on historical data to estimate the progression probability for each subject. Novel cohort will also include age-matched healthy controls as well as end-stage established OA patients assigned to 'dominant' progressive subclasses of clinically defined knee osteoarthritis with potential involvement of hip and/or hand OA with each a paired non-progressive knee OA phenotype","ontologyTerms":null,"unit":null,"characteristic":"description"},{"text":"knee osteoarthritis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005416"],"unit":null,"characteristic":"disease state"},{"text":"osteoarthritis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005178"],"unit":null,"characteristic":"disease state"},{"text":"3343","ontologyTerms":null,"unit":null,"characteristic":"number of patients"},{"text":"Homo sapiens","ontologyTerms":["http://purl.obolibrary.org/obo/NCBITaxon_9606"],"unit":null,"characteristic":"organism"},{"text":"APPROACH","ontologyTerms":["https://www.approachproject.eu/"],"unit":null,"characteristic":"project"},{"text":"historical clinical data","ontologyTerms":null,"unit":null,"characteristic":"sample type"},{"text":"imaging data","ontologyTerms":null,"unit":null,"characteristic":"sample type"},{"text":"biomarkers","ontologyTerms":["http://www.ebi.ac.uk/efo/EFO_0005127"],"unit":null,"characteristic":"sample type"},{"text":"All baseline cohort parameters, clinical, conventional (knee x-ray and MRI and the robust biochemical markers), and novel markers (T2 relaxation MRI for cartilage collagen distribution, gagCEST MRI cartilage for proteoglycan content, knee CT/x-ray for bone shape and trabecular architecture, knee motion, and novel biochemical markers describing turnover of specific tissue component, as well as involvement of hand, hip and spine joint damage, hand joint inflammation, hip motion and shape and bone architecture) will be used to identify (a set of) predictors that can discriminate between the knee OA progressors and (paired) non-progressors within a specific phenotype.","ontologyTerms":null,"unit":null,"characteristic":"study description"}],null,null,null,[{"url":"https://datacatalog.elixir-luxembourg.org/e/study/dc9a475c-147a-11eb-b51f-8c8590c45a21","duo":[]}],{"self":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14391556"},"curationLinks":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14391556/curationlinks"},"samples":null,"curationLink":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14391556/curationlinks/{hash}"}}]
["SAMEA14391557","APPROACH prospective longitudinal cohort","2022-05-16T10:26:56.132Z","2021-06-01T00:00:00Z","2022-05-16T10:26:56.132Z",9606,[{"text":"44-82 years","ontologyTerms":["http://purl.obolibrary.org/obo/UO_0000036"],"unit":null,"characteristic":"age"},{"text":"18.3-47.5 kg/m2","ontologyTerms":null,"unit":null,"characteristic":"bmi"},{"text":"Cohort of 297 patients (230 female, 67 male) diagnosed with OA and selected for the expected progression of their condition","ontologyTerms":null,"unit":null,"characteristic":"description"},{"text":"knee osteoarthritis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005416"],"unit":null,"characteristic":"disease state"},{"text":"osteoarthritis","ontologyTerms":["http://purl.obolibrary.org/obo/MONDO_0005178"],"unit":null,"characteristic":"disease state"},{"text":"1.39-2.04 meters","ontologyTerms":["http://purl.obolibrary.org/obo/UO_0000008"],"unit":null,"characteristic":"height"},{"text":"297","ontologyTerms":null,"unit":null,"characteristic":"number of patients"},{"text":"Homo sapiens","ontologyTerms":["http://purl.obolibrary.org/obo/NCBITaxon_9606"],"unit":null,"characteristic":"organism"},{"text":"urine","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C13283"],"unit":null,"characteristic":"organism part"},{"text":"serum","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C13325"],"unit":null,"characteristic":"organism part"},{"text":"blood","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C12434"],"unit":null,"characteristic":"organism part"},{"text":"APPROACH","ontologyTerms":["https://www.approachproject.eu/"],"unit":null,"characteristic":"project"},{"text":"questionnaire","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C17048"],"unit":null,"characteristic":"sample type"},{"text":"imaging data","ontologyTerms":null,"unit":null,"characteristic":"sample type"},{"text":"biomarkers","ontologyTerms":["http://www.ebi.ac.uk/efo/EFO_0005127"],"unit":null,"characteristic":"sample type"},{"text":"tissue sample","ontologyTerms":["http://purl.obolibrary.org/obo/NCIT_C19697"],"unit":null,"characteristic":"sample type"},{"text":"clinical data","ontologyTerms":null,"unit":null,"characteristic":"sample type"},{"text":"APPROACH prospective longitudinal study of knee osteoarthritis progression to support drug development","ontologyTerms":null,"unit":null,"characteristic":"study description"},{"text":"47-140 kg","ontologyTerms":["http://purl.obolibrary.org/obo/UO_0000009"],"unit":null,"characteristic":"weight"}],null,null,null,[{"url":"https://datacatalog.elixir-luxembourg.org/e/study/df77529e-c79d-11ec-9b1d-acde48001122","duo":[]}],{"self":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14391557"},"curationLinks":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14391557/curationlinks"},"samples":null,"curationLink":{"href":"https://www.ebi.ac.uk/biosamples/samples/SAMEA14391557/curationlinks/{hash}"}}]