Model organism or animal
BioSampleModel
2022-09-15
ENA-FIRST-PUBLIC
2022-09-15
ENA-LAST-UPDATE
SAMN30826986
External Id
pda|yiyuncao@orcid
INSDC center alias
pda|yiyuncao@orcid
INSDC center name
2022-09-15T01:36:31Z
INSDC first public
2022-09-15T01:36:31Z
INSDC last update
public
INSDC status
SRS15123020
SRA accession
bulk RNA-seq of colonic IECs from mice colonized with aat+/-M. morganii
Submitter Id
10 week
age
C57BL/6J
breed
NCBI
broker name
intestinal epithelial cells
cell_type
house mouse
common name
To evaluate the impacts of M. morganii-derived indolimines in vivo, we compared the effects of aat+ and aat- M. morganii strains on the intestinal epithelium using monocolonized mice. After colonized with aat+ M. morganii and fed IAld and leucine (precursors of indolimine-214), mice were sacrificed to isolate colonic intestinal epithelial cells (IECs) for bulk RNA-seq and Gene Ontology analyses of differentially expressed genes.
description
Mus musculus
http://purl.obolibrary.org/obo/NCBITaxon_10090
organism
female
sex
Colon
tissue
bulk RNA-seq of colonic IECs
title
mice colonized with indolimine-producing or non-indolimine-producing M. morganii
treatment