SAMN28844342
External Id
Trinity College Dublin
INSDC center name
2022-09-29T00:50:19.123Z
INSDC first public
2022-09-29T00:50:19.123Z
INSDC last update
SRS13283522
INSDC secondary accession
live
INSDC status
Microbe, viral or environmental
NCBI submission model
Microbe.1.0
NCBI submission package
SRS13283522
SRA accession
2018-12
collection_date
A novel accelerated evolution approach was used to obtain lager yeasts with altered flavour profiles through the temporary inhibition of the cells' stress response by applying a severe short heat stress or by treatment of cells with radicicol, a Hsp90p, inhibitor. Both treatments have previously been shown to induce aneuploidy and/or chromosomal recombination. Resistance to amino acid analogues of phenylalanine was used to select strains with an increased flux towards the production of higher alcohols and esters.
description
Ireland: Dublin
geo_loc_name
mutant 9.7
isolate
Laboratory
isolation_source
Saccharomyces pastorianus
http://purl.obolibrary.org/obo/NCBITaxon_27292
organism
cell culture
sample_type
Weihenstephan 34/70
strain
Microbe sample from Saccharomyces pastorianus Weihenstephan 34/70 mutant 9.7
title