SAMN21505319
External Id
Cochin hospital
INSDC center name
2022-10-02T00:50:16.297Z
INSDC first public
2022-10-02T00:50:16.297Z
INSDC last update
live
INSDC status
Pathogen.cl
NCBI submission model
Pathogen.cl.1.0
NCBI submission package
Dr Hedi MAMMERI
collected_by
2021-02-14
collection_date
Comparative genomic analysis of two related Serratia marcescens clinical isolates showed that the G690del mutation in the cpxA gene, which encodes the histidine kinase of the two components system CpxA/CpxR, was responsible for a premature stop codon leading to a truncated protein. The mutant displayed an acquired resistance to extended-spectrum cephalosporins, aminoglycosides and ciprofloxacin.
description
France: Paris
geo_loc_name
Homo sapiens
host
Intra-abdominal infection
host_disease
Intra-abdominal
isolation_source
48.51 N 2.21 E
lat_lon
Serratia marcescens
http://purl.obolibrary.org/obo/NCBITaxon_615
organism
Hat_S
strain
Emergence of pan-resistant Serratia marcescens clinical isolate upon loss of cpxA activity
title