SAMN26804952
External Id
Chinese Academy of Sciences
INSDC center name
2022-10-10T00:00:00Z
INSDC first public
2022-10-20T09:31:24.605Z
INSDC last update
SRS12290961
INSDC secondary accession
live
INSDC status
SARS-CoV-2: clinical or host-associated
NCBI submission model
SARS-CoV-2.cl.1.0
NCBI submission package
SRS12290961
SRA accession
Vero cells
cell line
The Chinese Academy of Medical Sciences
collected_by
2021-03-01
collection_date
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global pandemic, resulting in great fatalities around the world. Although the antiviral roles of RNA interference (RNAi) in plants, nematodes and insects have been well studied, the antiviral roles of RNAi in mammalians are still debating, for RNAi effect is suspected to be suppressed by interferon (IFN) signaling pathways in most cell types. To determine the role of RNAi in mammalian resistance to SARS-CoV-2, we studied the profiling of host small RNAs and SARS-CoV-2 virus-derived small RNAs (vsRNAs) in the early infection stages of Vero cells, an IFN-deficient cell line.
description
China: Beijing
geo_loc_name
Chlorocebus aethiops
host
COVID-19
host_disease
Severe acute respiratory syndrome coronavirus 2
http://purl.obolibrary.org/obo/NCBITaxon_2697049
organism
SARS-CoV-2: clinical or host-associated sample from Severe acute respiratory syndrome coronavirus 2
title