SAMN35016133
External Id
The University of Sydney
INSDC center name
2023-05-24T00:00:00Z
INSDC first public
2023-05-24T07:01:34.040Z
INSDC last update
SRS17806547
INSDC secondary accession
live
INSDC status
Model organism or animal
NCBI submission model
Model.organism.animal.1.0
NCBI submission package
SRS17806547
SRA accession
1426
cell_line
Devil facial tumour 1
cell_type
The Tasmanian devil (Sarcophilus harrisii) is endangered due to the spread of Devil Facial Tumour Disease (DFTD), a contagious cancer with no current treatment options. Here we test whether seven recently characterized Tasmanian devil cathelicidins are toxic to DFTD and/or involved in cancer regulation. DFT1 1426 cells were treated with one of seven cathelicidins (Saha-CATH1, 2, 3, 4, 5, 6 or 7) in triplicate, as well as a vehicle control (n = 24 total). Total RNA was extracted from each sample and Illumina TruSeq mRNA libraries prepared, which were sequenced as 2 x 150bp paired-end reads across an SP flowcell on the NovaSeq6000
description
Sarcophilus harrisii
http://purl.obolibrary.org/obo/NCBITaxon_9305
organism
DFT1
strain
Devil facial tumour 1
tissue
Devil facial tumour 1 1426 cells Saha-CATH7 treated
title
Saha-CATH7
treatment