SAMN20927858
External Id
Institute of Tropical Medicine
INSDC center name
2022-09-01T01:44:02.210Z
INSDC first public
2022-09-01T01:44:02.210Z
INSDC last update
SRS9909112
INSDC secondary accession
live
INSDC status
Microbe, viral or environmental
NCBI submission model
Microbe.1.0
NCBI submission package
SRS9909112
SRA accession
2019-09-13/2019-10-23
collection_date
We report the first experimental evidence that sustained chlorhexidine exposure can result in reduced susceptibility to chlorhexidine in N. gonorrhoeae. Our results suggest that intense exposure to chlorhexidine may result in resistance associated mutations in N. gonorrhoeae in three different efflux pumps: the MATE, RND and ABC transporters. Exposure to sub-lethal chlorhexidine concentrations may not only enhance resistance to chlorhexidine itself but also cross-resistance to other antibiotics.
description
Belgium: Antwerp
geo_loc_name
Homo sapiens
host
Neisseria gonorrhoeae
http://purl.obolibrary.org/obo/NCBITaxon_485
organism
cell culture
sample_type
WHO-F
strain
Chlorhexidine resistance evolution in Neisseria gonorrhoeae
title