P-0017411-T03-TB3
ERS3037772
SRA accession
Human
http://purl.obolibrary.org/obo/NCBITaxon_9606
common name
P-0017411-T03-TB3_vs_NORMAL.vcf
description
Homo sapiens
http://purl.obolibrary.org/obo/NCBITaxon_9606
organism
Homo sapiens
http://purl.obolibrary.org/obo/NCBITaxon_9606
scientific name
P-0017411
subject
Targeted next-generation sequencing was performed in patients with IDH1 or IDH2 mutations. Here we describe 4 cases where mutant IDH isoform switching serves as a mechanism of acquired clinical resistance to mutant IDH inhibition.
submission description
GSB-587
submission identifier
Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition
submission title