SAMN21399558
External Id
Shandong Academy of Agryculture Science
INSDC center name
2023-10-01T00:53:14.360Z
INSDC first public
2023-10-01T00:53:14.360Z
INSDC last update
live
INSDC status
Plant
NCBI submission model
Plant.1.0
NCBI submission package
ERS16667358
SRA accession
6 months
age
Bupleuri radix (Chaihu) is a well-known traditional Chinese medicinal herb that has been used more than 2000 years. In the Chinese Pharmacopoeia, Chaihu is recorded as the dried roots of Bupleurum chinense DC and B. scorzonerifolium Wild. Bupleurum species are officially listed in the Chinese and Japanese Pharmacopoeias and on the WHO monographs of commonly used medicinal plants in China and Korea. Due to their important medicinal role, the biosynthesis of saikosaponins from Bupleurum L. plants has been more intensively studied than any of their other metabolic processes or bioactive constituents. However, at present, a high-quality genomic sequence has not yet been produced for any Bupleurum species. To circumvent this and address current limitations in understanding the molecular evolution of this genus, we have reported a high-quality chromosome-level genome assembly of B. chinense DC. Our approach allowed us to obtain a final assembly comprising 945Mb of sequence and an N50 scaffold of 160 Mb. A total of 46,423 protein-coding genes were predicted in the B. chinense DC genome. Enrichment analyses suggested that the gene families that expanded during the evolution of B. chinense DC are involved in the biosynthesis of anthocyanins, sesquiterpenoids, and triterpenoids. Furthermore, we identified and analyzed the genes involved in the biosynthesis of saikosaponins and estimated the divergence time between the euasterid I and II clades. The newly generated genomic data provides a valuable resource for future investigations of the molecular mechanisms, biological functions, and evolutionary adaptations of B. chinense DC.
description
China
geo_loc_name
SDZQ12
isolate
Bupleurum chinense
http://purl.obolibrary.org/obo/NCBITaxon_52451
organism
leaf
tissue
Plant sample from Bupleuri radix
title