SAMN37408535
External Id
Northwestern University Feinberg School of Medicine
INSDC center name
2023-09-15T00:00:00Z
INSDC first public
2023-09-15T11:01:13.617Z
INSDC last update
SRS18888529
INSDC secondary accession
live
INSDC status
SARS-CoV-2: clinical or host-associated
NCBI submission model
SARS-CoV-2.cl.1.0
NCBI submission package
SRS18888529
SRA accession
Laboratory of Justin Richner at the University of Illinois at Chicago
collected_by
2021-05-03
collection_date
Whole tissue dissection
collection_method
none
date_of_sars_cov_2_vaccination
BALB/c mice were challenged intranasally with 7x10^3 plaque forming units (PFU) of SARS-CoV-2/MA10 and euthanized at 5-days post infection. Whole lung and brain tissue was dissected and RNA extracted for viral whole genome sequencing.
description
BALB/c (Jax Strain #00651) mice were challenged intranasally with 7*10^3 plaque-forming units (PFU) of SARS-CoV-2/MA10 and tissue was harvested at 5 days post-infection.
exposure_event
USA: Illinois, Chicago
geo_loc_name
Homo sapiens
host
brain
host_anatomical_part
COVID-19
host_disease
SARS-CoV-2/MA10 (mouse-adapted)
isolate
Obtained from BEI Resources (NR-55329)
isolation_source
Severe acute respiratory syndrome coronavirus 2
http://purl.obolibrary.org/obo/NCBITaxon_2697049
organism
Virus was propagated on Vero-E6 cells (ATCC) for one passage prior to use.
passage_method
1
passage_number
no
prior_sars_cov_2_vaccination
N (orf9)
sars_cov_2_diag_gene_name_1
18.46860122680664
sars_cov_2_diag_pcr_ct_value_1
Center for Pathogen Genomics and Microbial Evolution (CPGME) at Northwestern University, Chicago, Illinois
sequenced_by
MA10_m5_brain
title
None.
vaccine_received