characteristics.text: 2012-12-31T17:01:40Z
characteristics.characteristic: ENA-FIRST-PUBLIC
characteristics.text: 2018-03-08T15:46:19Z
characteristics.characteristic: ENA-LAST-UPDATE
characteristics.text: SAMEA1691827
characteristics.characteristic: External Id
characteristics.text: Wistar Genomics Facility
characteristics.characteristic: INSDC center name
characteristics.text: 2012-12-31T17:01:40Z
characteristics.characteristic: INSDC first public
characteristics.text: 2018-03-08T15:46:19Z
characteristics.characteristic: INSDC last update
characteristics.text: public
characteristics.characteristic: INSDC status
characteristics.text: ERS140942
characteristics.characteristic: SRA accession
characteristics.text: E-MTAB-1130:SIV.4356.post
characteristics.characteristic: Submitter Id
characteristics.text: ArrayExpress
characteristics.ontologyTerms: http://www.ebi.ac.uk/efo/EFO_0009737
characteristics.characteristic: broker name
characteristics.text: FirstPostiveViralLoad 2weeks
characteristics.characteristic: clinical information
characteristics.text: Rhesus monkey
characteristics.characteristic: common name
characteristics.text: Protocols: Two groups of six RMs were immunized with either the attenuated SIVDnef virus (group 1, SIV), which establishes a persistent low-level infection and induces protective immunity against high dose challenges with SIVmac, or with two doses of an AdHu5 vector expressing Gag of SIVmac239 (AdHu5gag) (group 2, AD), that was given at a two-month interval with the first dose given at the time of the SIVDnef inoculation to group 1. All RMs were challenged with ten weekly intra-rectal low-doses of SIVmac251 at a week interval starting nine months after the initial vaccination. During this period and for an additional eight weeks afterwards viral loads were measured by RT-PCR. Number of weeks after the first challenge when positive viral load was detected was used as FirstPostiveViralLoad factor. PBMC from whole blood were isolated using Ficoll gradient.
characteristics.characteristic: description
characteristics.text: simian immunodeficiency virus
characteristics.ontologyTerms: http://www.ebi.ac.uk/efo/EFO_0001675
characteristics.characteristic: disease state
characteristics.text: 4356
characteristics.characteristic: individual
characteristics.text: Macaca mulatta
characteristics.characteristic: organism
characteristics.text: Macaca mulatta
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/NCBITaxon_9544
characteristics.characteristic: organism
characteristics.text: post-vaccination 30weeks
characteristics.characteristic: sampling time point
characteristics.text: Macaca mulatta
characteristics.characteristic: scientific_name
characteristics.text: SIV.4356.post
characteristics.characteristic: title