characteristics.text: 2012-06-25T20:05:40Z
characteristics.characteristic: ENA-FIRST-PUBLIC
characteristics.text: 2018-03-08T15:33:19Z
characteristics.characteristic: ENA-LAST-UPDATE
characteristics.text: SAMEA1464828
characteristics.characteristic: External Id
characteristics.text: UNIVERSITY OF PENNSYLVANIA
characteristics.characteristic: INSDC center name
characteristics.text: 2012-06-25T20:05:40Z
characteristics.characteristic: INSDC first public
characteristics.text: 2018-03-08T15:33:19Z
characteristics.characteristic: INSDC last update
characteristics.text: public
characteristics.characteristic: INSDC status
characteristics.text: ERS074991
characteristics.characteristic: SRA accession
characteristics.text: 129J/BL6
characteristics.characteristic: StrainOrLine
characteristics.text: E-MTAB-805:Treated-Female-Control
characteristics.characteristic: Submitter Id
characteristics.text: ArrayExpress
characteristics.ontologyTerms: http://www.ebi.ac.uk/efo/EFO_0009737
characteristics.characteristic: broker name
characteristics.text: house mouse
characteristics.characteristic: common name
characteristics.text: Protocols: Briefly, 14-15 day old mice were injected with DEN (20 mg/kg body weight) (Sigma) to initiate tumor growth. Beginning at 28 days, mice were injected with TCPOBOP (3 mg/kg bodyweight) (Sigma) once every two weeks for a total of eight times to promote tumor growth.DEN-induced liver injury experiments were carried out as described previously (Naugler etal., 2007), except that 50 mg/kg body weight Faslodex or estrogen were intraperitoneally injected daily for seven days before DEN treatment. The human samples were not treated. Chromatin was extracted from mouse livers following the protocol described in Li et al. NSMB 2011 [PMID 21623366]. ChIP was performed on the liver chromatin samples. ChIP-DNA was prepared for sequencing with the Illumina GAII sequencer at the Functional Genomics Center at the Institute for Diabetes, Obesity and Metabolismat the University of Pennsylvania.
characteristics.characteristic: description
characteristics.text: Foxa1loxP/loxP;Foxa2loxP/loxP
characteristics.characteristic: genotype
characteristics.text: Mus musculus
characteristics.characteristic: organism
characteristics.text: Mus musculus
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/NCBITaxon_10090
characteristics.characteristic: organism
characteristics.text: liver
characteristics.characteristic: organism part
characteristics.text: Mus musculus
characteristics.characteristic: scientific_name
characteristics.text: female
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/PATO_0000383
characteristics.characteristic: sex
characteristics.text: Treated-Female-Control
characteristics.characteristic: title