2024-09-19
ENA first public
ERC000050
ENA-CHECKLIST
EMBL Heidelberg
INSDC center name
public
INSDC status
ERS21058129
SRA accession
spire_mag_00780021
Submitter Id
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly quality
megahit 1.2.9
assembly software
default
binning parameters
metabat 2.12.1
binning software
human digestive system
broad-scale environmental context
EBI-EMG
broker name
2017
collection date
88.39
%
completeness score
checkm2 0.1.3
completeness software
2.31
%
contamination score
This sample represents a Third Party Annotation (TPA) binned metagenome assembled from the metagenomic run ERR2868469 of study ERP111669.
description
stool
environmental medium
China
geographic location (country and/or sea)
missing: third party data
DD
geographic location (latitude)
missing: third party data
DD
geographic location (longitude)
metagenome-assembled genome
investigation type
human gut metagenome
isolation_source
human gut
local environmental context
human gut metagenome
metagenomic source
Phocaeicola vulgatus
organism
Public description： Ankylosing spondylitis (AS) is a common autoimmune disease. Due to the early pathogenesis and long duration, patients suffer from morning stiffness, low back pain, chest pain, alternating hip pain and other symptoms. And the disability rate is high, which seriously affects the quality of life. According to statistics, the prevalence of ankylosing spondylitis in China is about 0.3%, mostly young men. On average, patients need to stop working after fifteen or six years of illness. After 20 years of illness, more than 85% of patients lose the ability to live independently and become so-called "puppet people." In response to key scientific issues, these datas is devoted to the use a metagenomic wide association studies to explore new key biomarkers and therapeutic targets of AS from intestinal micro-organisms, so as to improve early diagnosis, accurate prediction and classification, and improve prognosis.And combine with other datas which already published of autoimmune disease,we identified conflicts and contradicts points of RA ,AS ,behcet disease and T1D.
project name
SAMEA5054123
sample derived from
Phocaeicola vulgatus
scientific_name
Illumina HiSeq 2000
sequencing method
multi-marker approach
taxonomic identity marker
binned metagenome: spire_mag_00780021
title