2024-09-19
ENA first public
ERC000050
ENA-CHECKLIST
EMBL Heidelberg
INSDC center name
public
INSDC status
ERS21060730
SRA accession
spire_mag_01087127
Submitter Id
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly quality
megahit 1.2.9
assembly software
default
binning parameters
metabat 2.12.1
binning software
human digestive system
broad-scale environmental context
EBI-EMG
broker name
2013/2015
collection date
96.6
%
completeness score
checkm2 0.1.3
completeness software
4.73
%
contamination score
This sample represents a Third Party Annotation (TPA) binned metagenome assembled from the metagenomic runs ERR1912954,ERR1913148,ERR1912953,ERR1913145,ERR1912955,ERR1913146,ERR1912956,ERR1913147 of study ERP019674.
description
stool
environmental medium
Germany
geographic location (country and/or sea)
50.942911
DD
geographic location (latitude)
6.967314
DD
geographic location (longitude)
metagenome-assembled genome
investigation type
human gut metagenome
isolation_source
human gut
local environmental context
human gut metagenome
metagenomic source
Phocaeicola vulgatus
organism
Parkinson’s disease (PD) presently is conceptualized as a protein aggregation disease in which pathology involves both, the enteric and the central nervous system, possibly spreading from one to another via the vagus nerves. As gastrointestinal dysfunction often precedes or parallels motor symptoms, the enteric system with its vast diversity of microorganisms may be involved in PD pathogenesis. Alterations in the enteric microbial taxonomic level of L-DOPA-naïve PD patients might also serve as a biomarker.We thus compared the fecal microbiomes of 31 early stage, L-DOPA-naive PD subjects to 28 age matched controls by metagenomic analysis.
project name
SAMEA103958125
sample derived from
Phocaeicola vulgatus
scientific_name
Illumina HiSeq 2500
sequencing method
multi-marker approach
taxonomic identity marker
binned metagenome: spire_mag_01087127
title