2024-09-20
ENA first public
ERC000050
ENA-CHECKLIST
EMBL Heidelberg
INSDC center name
public
INSDC status
ERS21065779
SRA accession
spire_mag_01732424
Submitter Id
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly quality
megahit 1.2.9
assembly software
default
binning parameters
metabat 2.12.1
binning software
human digestive system
broad-scale environmental context
EBI-EMG
broker name
2017-09-01
collection date
88.44
%
completeness score
checkm2 0.1.3
completeness software
3.05
%
contamination score
This sample represents a Third Party Annotation (TPA) binned metagenome assembled from the metagenomic run ERR2759412 of study ERP110580.
description
not specified
environmental medium
China
geographic location (country and/or sea)
39.90000000
DD
geographic location (latitude)
116.30000000
DD
geographic location (longitude)
metagenome-assembled genome
investigation type
human gut metagenome
isolation_source
human gut
local environmental context
human gut metagenome
metagenomic source
Bacteroides uniformis
organism
With the establishment of the heart-gut axis concept, accumulating studies suggest that the gut microbiome plays an important role in the genesis of cardiovascular diseases. Yet, little evidence has been reported characterizing the gut microbiota shift in correspondence to arrhythmia, particularly in atrial fibrillation, the most common type of cardiac arrhythmia with worldwide prevalence. We include the first result of the global alterations that occur in the intestinal microbiota based on a strategy of metagenomic and metabolomic analyses. Our findings characterize the disordered gut microbiota and microbial metabolite profiles in atrial fibrillation. Intervention strategies targeting microbiome composition to counteract the progression of atrial fibrillation are highly suggested.
project name
SAMEA4867864
sample derived from
Bacteroides uniformis
scientific_name
Illumina NovaSeq 6000
sequencing method
multi-marker approach
taxonomic identity marker
binned metagenome: spire_mag_01732424
title