characteristics.text: SAMN16619887
characteristics.characteristic: External Id
characteristics.text: Ningbo Kangning Hospital, Ningbo Institute of Microcirculation and Henbane, Ningbo University
characteristics.characteristic: INSDC center name
characteristics.text: 2024-10-01T00:53:12.150Z
characteristics.characteristic: INSDC first public
characteristics.text: 2024-10-01T00:53:12.150Z
characteristics.characteristic: INSDC last update
characteristics.text: SRS7710080
characteristics.characteristic: INSDC secondary accession
characteristics.text: live
characteristics.characteristic: INSDC status
characteristics.text: Model organism or animal
characteristics.characteristic: NCBI submission model
characteristics.text: Model.organism.animal.1.0
characteristics.characteristic: NCBI submission package
characteristics.text: SRS7710080
characteristics.characteristic: SRA accession
characteristics.text: 6-8 weeks
characteristics.characteristic: age
characteristics.text: Rat
characteristics.characteristic: breed
characteristics.text: Sprague Dawley
characteristics.characteristic: cultivar
characteristics.text: 250 to 300 g
characteristics.characteristic: dev_stage
characteristics.text: Sprague Dawley
characteristics.characteristic: ecotype
characteristics.text: The S1_3 rats were trained to self-administer heroin under a fixed ratio paradigm for 4 h daily in operant chambers which equipped with two nose pokes (ENV-114 M, Med Associates, St. Albans, VT). Each response in the active hole was immediately reinforced with an infusion of heroin (0.5 mg/kg) via the pump over 4 s, at the same time was accompanied by the noise of the infusion pump and illumination of the stimulus light located above the active nose poke for 20 s. The number of responses during this 20 s period was recorded, but there was no delivery of heroin. Daily training sessions were conducted over 14 consecutive days. The criterion of stable heroin self-administration was defined as less than 10% of the variability in the number of active nose poking responses that rats touched on the last 3 days .
characteristics.characteristic: isolate
characteristics.text: Rattus norvegicus
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/NCBITaxon_10116
characteristics.characteristic: organism
characteristics.text: male
characteristics.characteristic: sex
characteristics.text: not applicable
characteristics.characteristic: strain
characteristics.text: Nucleus accumbens
characteristics.characteristic: tissue
characteristics.text: biological replicate 3
characteristics.characteristic: title