SAMN41059642
External Id
Ain Shams University, Faculty of Pharmacy
INSDC center name
2024-04-23T00:00:00Z
INSDC first public
2024-04-23T17:42:55.280Z
INSDC last update
live
INSDC status
Microbe, viral or environmental
NCBI submission model
Microbe.1.0
NCBI submission package
ERS19293822
SRA accession
2024-03-25
collection_date
Metagenomic Nanopore Sequencing for identifying the antimicrobial metabolite biosynthetic gene clusters of Bacillus licheniformis. In this study, whole metagenome analysis of the soil sample(s) was performed using MinION (Oxford Nanopore Technologies). The antimicrobial metabolite biosynthetic gene clusters were extracted, identified, and annotated using the AntiSMASH software. Results revealed that the biosynthetic gene clusters of lichenicidin VK21 A1/lichenicidin VK21 A2, bacillibactin/bacillibactin E/bacillibactin F, fengycin, butirosin A/butirosin B, lichenysin and laterocidine were conserved in the genome of Bacillus licheniformis isolate CCASU-B18. This strain exhibited antimicrobial activities against several multidrug-resistant (MDR) pathogens including Gram-positive and Gram-negative bacteria as well as MDR Candida albicans. This is the first report for identifying the fengycin, butirosin A/butirosin B, lichenysin and laterocidine biosynthetic gene clusters in the endophytic Bacillus licheniformis.
description
Egypt
geo_loc_name
Bassia scoparia
host
CCASU-B18
isolate
environment
isolation_source
Bacillus licheniformis
http://purl.obolibrary.org/obo/NCBITaxon_1402
organism
bacteria
sample_type
Microbe sample from Bacillus licheniformis
title