SAMN43213410
External Id
Wayne State University
INSDC center name
2024-08-15T00:00:00Z
INSDC first public
2024-08-20T19:13:34.039Z
INSDC last update
live
INSDC status
Pathogen.cl
NCBI submission model
Pathogen.cl.1.0
NCBI submission package
Baltz > Bayer > Rybak
Provenance
Cubist Pharmaceuticals
collected_by
unknown
collection_date
ST256-MRSA-IVa CC45
genotype
unknown
geo_loc_name
Homo sapiens
host
Clinical bloodstream isolate CUBIST-23 is part of the Cubist Pharmaceuticals Isolate Collection. CUBIST-23 is the daptomycin-resistant isolate of the CUBIST-22/CUBIST-23 sequential isolate paired strains obtained from a patient with endovascular staphylococcal infection following daptomycin treatment failure. It is multilocus sequence type 256, clonal complex 45, SCCmec-II (+), spa type t004 / A2-A1-K1-E1-E1-M1-B1-K1-B1. Compared to CUBIST-22, CUBIST-23 has sequence variations in walK (M205T), mprF (S295L) and in cls2 (K481I). It was previously described in a 2015 report as strain "C23".
host_description
staphylococcal endovascular infection
host_disease
blood
isolation_source
unknown
lat_lon
Staphylococcus aureus
http://purl.obolibrary.org/obo/NCBITaxon_1280
organism
CUBIST-23
strain
CUBIST-23
title