SAMN43180331
External Id
Huazhong Agricultural University
INSDC center name
2024-08-15T00:00:00Z
INSDC first public
2024-08-16T02:24:21.257Z
INSDC last update
SRS22369385
INSDC secondary accession
live
INSDC status
Plant
NCBI submission model
Plant.1.0
NCBI submission package
SRS22369385
SRA accession
not collected
age
2024
collection_date
Jin668
cultivar
N6-methyladenosine (m6A) is the most prevalent internal modification of mRNA. It plays an important role in regulating plant growth, development, and stress resistance. There is still a lack of effective tools to precisely modify m6A sites of individual transcripts in plants. Here, we have developed programmable m6A editing tools by combining CRISPR/dCas13(Rx) with the methyltransferase GhMTA (Targeted RNA Methylation Editor, TME) or the demethyltransferase GhALKBH10 (Targeted RNA Demethylation Editor, TDE).
description
China: Hubei
geo_loc_name
Gossypium hirsutum
http://purl.obolibrary.org/obo/NCBITaxon_3635
organism
leaf
tissue
CRISPR/dCas13(Rx) Derived RNA N6-methyladenosine (m6A) Dynamic Modification in Plant: ATAC-seq
title