SAMN40043176
External Id
Universitas Andalas
INSDC center name
2025-03-15T00:50:20.407Z
INSDC first public
2025-03-15T00:50:20.407Z
INSDC last update
live
INSDC status
Human
NCBI submission model
Human.1.0
NCBI submission package
31
age
PDRPI FK Unand, Jati, Kec. Padang Tim., Kota Padang, Sumatera Barat 25129
biomaterial_provider
2021
collection_date
The immunopathological process of COVID-19 begins when SARS-CoV-2 enters and binds to the ACE2 receptor, triggering a coagulation cascade in both extrinsic and intrinsic pathways. This includes profibrinolytic and fibrinolytic inhibitor processes, and the proteins involved in profibrinolytic are encoded by the PLAUR gene as plasminogen activators. Simultaneously, fibrinolytic inhibitors can impede fibrinolysis through the activation of proteins encoded by the A2M and SERPINE1 genes. Therefore, this research aims to assess the predictive genetic expression data of PLAUR and fibrinolytic inhibitor genes (SERPINE1, A2M) and their relationship with serum D-Dimer levels in COVID-19 patients. This research is expected to make a significant contribution to the global control of COVID-19.
description
Indonesia
geo_loc_name
Mild1
isolate
Homo sapiens
http://purl.obolibrary.org/obo/NCBITaxon_9606
organism
male
sex
Whole Blood
tissue
Human sample from Homo sapiens
title