SAMN41953765
External Id
National Institute of Allergy and Infectious Diseases
INSDC center name
2025-04-05T12:39:43.197Z
INSDC first public
2025-04-05T12:39:43.197Z
INSDC last update
live
INSDC status
Invertebrate
NCBI submission model
Invertebrate.1.0
NCBI submission package
4 days
age
1993
collection_date
Here we report a scaffold-level assembly and annotation of the genome of Xenopsylla cheopis, a rat flea widely present in warmer regions throughout the world which is of particular importance because it is the major vector of Yersinia pestis, the bacterial agent of bubonic plague, to humans. It is also the principal vector of Rickettsia typhi, the cause of murine typhus in humans. To facilitate assembly, our genome sequence was based on a single adult female X. cheopis. A total of 56,222 coding sequences were detected, analyzed, and annotated. Proteins predicted to be central to blood meal digestion, insect immune system pathways, and salivary gland output and function were investigated further, as well as the large number of transposable elements present in the genome. Future comparative analyses may provide insight into intrinsic factors that account for the very high vector competence of X. cheopis for Y. pestis transmission relative to the very low vector competence of C. felis.
description
adult
dev_stage
USA:Baltimore
geo_loc_name
Rattus rattus
host
whole body
host_tissue_sampled
RLM
isolate
Rocky Mountain Laboratories
note
Xenopsylla cheopis
http://purl.obolibrary.org/obo/NCBITaxon_163159
organism
pooled male and female
sex
whole organism
tissue
Xenopsylla cheopis genome assembly
title