2025-04-13
ENA first public
ERC000047
ENA-CHECKLIST
EMG
INSDC center name
public
INSDC status
ERS23989383
SRA accession
SRR25048808_binner13_Refined_3
Submitter Id
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly quality
megahit_vv1.2.9
assembly software
default
binning parameters
MGnify-genomes-generation-pipeline_v1.0.0
binning software
human digestive system
broad-scale environmental context
EBI-EMG
broker name
2021
collection date
81.46
%
completeness score
CheckM2_v1.0.1
completeness software
1.79
%
contamination score
This sample represents a Third Party Annotation (TPA) Metagenome-assembled genome assembled from the metagenomic run SRR25048808 of study SRP435676.
description
oral sample
environmental medium
Germany
geographic location (country and/or sea)
48.00500500
DD
geographic location (latitude)
7.84190400
DD
geographic location (longitude)
metagenome-assembled genome
investigation type
human oral metagenome
isolation_source
oral cavity
local environmental context
human oral metagenome
metagenomic source
Haemophilus parainfluenzae
organism
The increase of antimicrobial resistances (AMR) is a major concern for the global public health. The antiseptic chlorhexidine (CHX) is a frequently used disinfectant and discussed as possible factor in the emergence of cross-resistances against antibiotics. In our study, we analyzed the oral metagenome of 20 patients who applied two times daily a 0.2% CHX mouthwash for four weeks. Samples from saliva and supragingival plaque were examined before, directly after four weeks and another four weeks after stopping the CHX treatment. We analyzed the changes of the oral microbiota and the prevalence of antibiotic resistance genes (ARGs) in context with the CHX application. We performed paired-end sequencing but due to protection of data privacy, we provide adjusted reads. Paired ends therefore are merged.
project name
SAMN33859020
sample derived from
Haemophilus parainfluenzae
scientific_name
Illumina NovaSeq 6000
sequencing method
multi-marker approach
taxonomic identity marker
Metagenome-assembled genome: SRR25048808_binner13_Refined_3
title