2025-12-08
ENA first public
ERC000011
ENA-CHECKLIST
iTeos Therapeutics
INSDC center name
public
INSDC status
ERS25372227
SRA accession
E-MTAB-15430:11530069B0048W
Submitter Id
ArrayExpress
broker name
not collected
collection date
human
common name
Protocols: Biopsies from 6 cancer patients (head and neck n=1, melanoma n=3, lung n=1, prostate n=1) enrolled in Phase I study IO-001 were processed at screening and C1D21.   Up to five FFPE sections per tissue sample were used, for HE staining and RNA extraction. For each sample a capture area of 6.5 x 6.5 mm (5.000 spots) was annotated by a pathologist. RNA extraction was performed with the High Pure FFPET RNA extraction Kit (Roche). DV200 values were evaluated using BioAnalyzer (Agilent Technologies), and only samples with DV200 values superior to 30% were included in the analysis.  Libraries were prepared using the 10x Genomics PCR-based protocol.
description
Malignant melanoma
disease
not collected
geographic location (country and/or sea)
01-008
individual
not applicable
isolate
Homo sapiens
organism
Homo sapiens
organism
C1D21
sampling time point
Homo sapiens
scientific_name
11530069B0048W
title