characteristics.text: SAMN52827566
characteristics.characteristic: External Id
characteristics.text: University of Pennsylvania
characteristics.characteristic: INSDC center name
characteristics.text: 2025-10-16T00:00:00Z
characteristics.characteristic: INSDC first public
characteristics.text: 2025-10-16T18:51:51.883Z
characteristics.characteristic: INSDC last update
characteristics.text: SRS26864614
characteristics.characteristic: INSDC secondary accession
characteristics.text: live
characteristics.characteristic: INSDC status
characteristics.text: Human
characteristics.characteristic: NCBI submission model
characteristics.text: Human.1.0
characteristics.characteristic: NCBI submission package
characteristics.text: SRS26864614
characteristics.characteristic: SRA accession
characteristics.text: 34 years
characteristics.characteristic: age
characteristics.text: Carl H. June, Perelman School of Medicine, University of Pennsylvania, Smilow Center for Translational Research, 3400 Civic Center Boulevard, Building 421, 8th Floor, Room 123, Philadelphia, PA. 19104-5156
characteristics.characteristic: biomaterial_provider
characteristics.text: 2024-08-13
characteristics.characteristic: collection_date
characteristics.text: scDNA Seq data from a custom Mission BioTapestri amplicon panel, designed to capture 56 potential ABE target regions across the human genome including the 20 distinct target genes that have been edited in these samples (CD3E, B2M, CIITA, PVR, CD52, ICAM1, CD58, PDCD1, CTLA4, CD5, RASA2, MED12, ZC3H12A, RC3H1, TET2, ARID1A, SMARCC1, SMARCA4, SMYD3, ADORA2A).
characteristics.characteristic: description
characteristics.text: USA: Philadelphia, Pennsylvania
characteristics.characteristic: geo_loc_name
characteristics.text: Healthy human donor
characteristics.characteristic: isolate
characteristics.text: Homo sapiens
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/NCBITaxon_9606
characteristics.characteristic: organism
characteristics.text: male
characteristics.characteristic: sex
characteristics.text: Primary human T cells
characteristics.characteristic: tissue
characteristics.text: Human sample from Homo sapiens
characteristics.characteristic: title
characteristics.text: Multiplex adenine base editing of 20 distinct genes (CD3E, B2M, CIITA, PVR, CD52, ICAM1, CD58, PDCD1, CTLA4, CD5, RASA2, MED12, ZC3H12A, RC3H1, TET2, ARID1A, SMARCC1, SMARCA4, SMYD3, ADORA2A) using a medium dose of gRNAs (0.38µg per gRNA)
characteristics.characteristic: treatment