characteristics.text: SAMD01703541
characteristics.characteristic: External Id
characteristics.text: Science Tokyo
characteristics.characteristic: INSDC center name
characteristics.text: 2025-11-10T00:00:00Z
characteristics.characteristic: INSDC first public
characteristics.text: 2025-11-11T14:46:24.373Z
characteristics.characteristic: INSDC last update
characteristics.text: DRS534110
characteristics.characteristic: INSDC secondary accession
characteristics.text: live
characteristics.characteristic: INSDC status
characteristics.text: Generic
characteristics.characteristic: NCBI submission model
characteristics.text: Generic.1.0
characteristics.characteristic: NCBI submission package
characteristics.text: DRS534110
characteristics.characteristic: SRA accession
characteristics.text: 1 month
characteristics.characteristic: age
characteristics.text: Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo
characteristics.characteristic: biomaterial_provider
characteristics.text: 2024-07
characteristics.characteristic: collection_date
characteristics.text: Liver tissue from 1-month-old male Jcl:ICR mouse injected with CRISPR-Cas3 mRNA LNP targeting Ttr; used to assess in vivo TTR knockdown and on-target/off-target editing.
characteristics.characteristic: description
characteristics.text: healthy
characteristics.characteristic: disease
characteristics.text: Japan:Tokyo, Institute of Medical Science, The University of Tokyo
characteristics.characteristic: geo_loc_name
characteristics.text: ICR_mouse_01
characteristics.characteristic: isolate
characteristics.text: rodent
characteristics.characteristic: karyotype
characteristics.text: Mus musculus
characteristics.ontologyTerms: http://purl.obolibrary.org/obo/NCBITaxon_10090
characteristics.characteristic: organism
characteristics.text: liver tissue
characteristics.characteristic: phenotype
characteristics.text: CRISPR-Cas3 mRNA LNP (DiT/Sep configuration) targeting Ttr
characteristics.characteristic: population
characteristics.text: Mouse_Cas3
characteristics.characteristic: sample_name
characteristics.text: male
characteristics.characteristic: sex
characteristics.text: liver
characteristics.characteristic: tissue
characteristics.text: ICR mouse liver after Cas3-LNP dosing
characteristics.characteristic: title