SAMN45028289
External Id
University of Chinese Academy of Sciences
INSDC center name
2026-01-01T00:56:20.520Z
INSDC first public
2026-01-01T00:56:20.520Z
INSDC last update
live
INSDC status
Generic
NCBI submission model
Generic.1.0
NCBI submission package
2022-06
collection_date
Our project aims to develop a joint reference genome that integrates the genomes of Mus musculus (mouse) and Murine Cytomegalovirus (MCMV) strain K181. This innovative endeavor not only consolidates the genomic information of the mouse but also focuses on refining and annotating the MCMV-K181 genome with enhanced detail. Compared to the existing MCMV-K181 genome (NCBI Taxonomy ID: txid69156, reported by Schoch et al., 2020), our joint reference genome offers significant improvements. Specifically, we have conducted a comprehensive re-annotation of the MCMV-K181 genome using the latest research data and advanced bioinformatics methods, resulting in the addition of several key genes, including M23, M36, M41.1, M60, M89, M112-113, and M122-123. These new gene annotations enrich our understanding of the MCMV-K181 genome and provide a more comprehensive and accurate genomic resource for our research on mapping single-cell RNA sequence reads to this joint genome. By constructing this joint reference genome, we hope to support more studies on the interactions between MCMV and its mouse host, further advancing the fields of virology, immunology, and genomics. Our work presents a new and improved genomic resource to the scientific community, aiding in the discovery of the mechanisms underlying MCMV infection and host immune responses.
description
[ENVO:00000428]
env_broad_scale
[ENVO:00002002]
env_local_scale
[ENVO:00002055] [ENVO:00002046]
env_medium
China: Wuhan Institute of Virology, Chinese Academy of Sciences. No. 262 Jinlong Street, Jiangxia District, Wuhan City.
geo_loc_name
Mus musculus, Murine cytomegalovirus (strain K181)
isolate
Mus musculus: Derived from the NCBI GenBank database: Genome assembly GRCm38, version GCF_000001635.20. This genome serves as the host component of the joint genome. Murine cytomegalovirus (strain K181): Sourced from the NCBI GenBank database, version GCA_027929935.1. Based on that, we performed a comprehensive re-annotation of the MCMV-K181 genome using the latest research data and advanced bioinformatics methods, adding several key genes, including M23, M36, M41.1, M60, M89, M112-113 and M122-123.
isolation_source
30.39 N 114.34 E
lat_lon
mixed sample
http://purl.obolibrary.org/obo/NCBITaxon_1427524
organism
MIMAG Metagenome-assembled Genome sample from Mus musculus and Murine Cytomegalovirus strain K181
title