text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: mouse monoclonal, raised against a fusion protein, corresponding to amino acids 1-647 of Human GST-WHSC1/NSD2.

characteristic: antibody antibodydescription

text: This is a probable histone methyltransferase, which may act as a transcription regulator that binds DNA and suppresses IL5 transcription.

text: abcam

text: Abcam

text: ATCC

text: F

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina Genome Analyzer IIx

characteristic: labversion description

text: Homo sapiens


status: PUBLIC

characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

tag: attribute

text: rabbit polyclonal. Antibody Target: H3K27ac

text: Histone H3 (acetyl K27). As with H3K9ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation has can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: ATCC

characteristic: biomaterial provider

text: immortalized cell line

characteristic: biomaterial type

text: M

text: std

text: Standard input signal for most experiments.

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

characteristic: line

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

characteristic: title

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K36me3

characteristic: antibody antibodydescription

text: Histone H3 (tri-methyl K36). Marks regions of RNAPII elongation, including coding and non-coding transcripts.

text: Specific for histone H3 tri methylated at lysine 36, weakly reacts with H3K36me2. Marks regions of RNAPII elongation, including coding and non-coding transcripts.

text: abcam

text: Abcam

text: ATCC

text: immortalized cell line

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

text: 1 h with 100 nM Dexamethasone (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: rabbit polyclonal. Antibody Target: H3K4me1

text: Histone H3 (mono methyl K4). Is associated with enhancers, and downstream of transcription starts.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: ATCC

characteristic: biomaterial provider

text: immortalized cell line

characteristic: biomaterial type

text: M

text: std

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

characteristic: line

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

characteristic: title

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K4me2

characteristic: antibody antibodydescription

text: Histone H3 (di methyl K4). Marks promoters and enhancers. Most CpG islands are marked by H3K4me2 in primary cells. May be associated also with poised promoters.

text: abcam

text: Abcam

text: ATCC

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina HiSeq 2000

text: Homo sapiens

text: 1 h with 0.02% Ethanol (Myers)

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: rabbit polyclonal. Antibody Target: H4K20me1

text: Histone H4 (mono-methyl K20). Is associated with active and accessible regions. In mammals, PR-Set7 specifically catalyzes H4K20 monomethylation. NOTE CONTRAST to H3K20me3 which is associated with heterochromatin and DNA repair.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: Rajinder Kaul, UW

characteristic: biomaterial provider

text: F

text: std

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

characteristic: title

text: No special treatment or protocol applies


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2. Antibody Target: EZH2

characteristic: antibody antibodydescription

text: EZH2 (Enhancer of Zeste homolog 2, also designated Enx1 and SETDB1) is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein. It contains a SET domain that catalyzes the methylation of histone H3 at lysine 27 (Histone H3 Lys27 monomethylated, dimethylated and trimethylated). Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and Suz12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. EZH2 associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Deregulation of EZH2 is linked to a variety of cancers.

text: Active Motif

text: Coriell; http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM12878

text: F

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: Rabbit polyclonal antibody raised against a peptide corresponding to the C-terminus of H2AZ. Antibody Target: H2AZ

text: H2A.Z is a sequence variant of Histone H2A.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: Upstate (Millipore)

text: Lonza

characteristic: biomaterial provider

text: U

text: std

text: NH-A/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

text: NH-A

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: Millipore

text: Upstate (Millipore)

text: Lonza

text: U

text: std

text: HMEC/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

text: HMEC

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: antibody antibodydescription

text: Active Motif

text: Lonza

text: U

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: HMEC/Input/std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

text: HMEC


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: Rabbit polyclonal antibody raised against a peptide containing K79 di-methylation. Antibody Target: H3K79me2

text: H3K79me2 is a mark of the transcriptional transition region - the region between the initiation marks (K4me3, etc) and the elongation marks (K36me3).

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: Lonza

characteristic: biomaterial provider

text: U

text: std

text: Osteobl/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

text: Osteobl

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K27me3

text: Histone H3 (tri-methyl K27). Marks promoters that are silenced by Polycomb proteins in a given lineage; large domains are found at inactive developmental loci.

text: Millipore

text: Lonza

text: in vitro differentiated cells

characteristic: biomaterial type

text: U

text: myotube

characteristic: cell type

text: std

text: Standard input signal for most experiments.

text: HSMMtube/None/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: donor id

characteristic: labversion

text: Illumina Genome Analyzer IIe

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

text: HSMMtube

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: HDAC6

characteristic: antibody antibodydescription

text: Histone deacetylase 6 (HDAC6) is a class II histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminus of core histones. HDAC6 has also been identified as a cytoplasmic deacetylase that acts on tubulin and HSP90 to influence cell motility. Recently HDAC6 has been found to be involved in the stress response as a component of cytoplasmic stress granules.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: ATCC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: Millipore

text: Upstate (Millipore)

text: Lonza

text: F

text: std

text: NHDF-Ad/None/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina Genome Analyzer IIx

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

text: NHDF-Ad

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: rabbit polyclonal. Antibody Target: H3K4me3

characteristic: antibody antibodydescription

text: Histone H3 (tri methyl K4). Marks promoters that are active or poised to be activated.

characteristic: antibody targetdescription

text: ab8580; 07-473

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: 1)abcam; 2)Millipore

text: Lonza

characteristic: biomaterial provider

text: primary cell

characteristic: biomaterial type

text: U

characteristic: cell sex

text: osteoblast

characteristic: cell type

text: std

characteristic: control

text: Osteobl/None/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: donor id

text: Illumina Genome Analyzer IIe

text: Homo sapiens

text: Osteobl

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

text: REST

characteristic: antibody

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid

text: A transcriptional repressor which represses neuronal genes in non-neuronal tissues. A member of the Kruppel-type zinc finger transcription factor family. Represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element (NRSE) by associating with two corepressors, mSin3 and CoREST, which recruit HDACs to the promoters of REST-regulated genes. Target is GST fusion amino acids 801-1097 of human REST.

text: Millipore

text: ATCC

text: F

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: CTCF

text: rabbit polyclonal. Antibody Target: CTCF

characteristic: antibody antibodydescription

text: Rabbit polyclonal. Antibody Target: CTCF

text: CTCF zinc finger transcription factor. A sequence specific DNA binding protein that functions as an insulator, blocking enhancer activity. It has also been suggested to block the spreading of chromatin structure in certain instances.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: S. Heimfeld Laboratory, FHCRC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

text: Homo sapiens

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_CTCF

text: No special treatment or protocol applies

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: PHF8

text: PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate. PHF8 is also known as ZNF422 and KIAA1111.

text: Bethyl Laboratories

text: WiCell Research Institute

text: M

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid Antibody Target: CHD4

text: CHD4/Mi2beta is a helicase component of the nucleosome remodeling and deacetylase (NuRD) complex that functions to remodel chromatin and repress transcription. Outside of the NuRD complex, CHD4/Mi2beta can function as an activator of transcription in association with p300 histone acetyltransferase.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: ATCC

text: F

text: std

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K4me2

text: Histone H3 (di methyl K4). Marks promoters and enhancers. Most CpG islands are marked by H3K4me2 in primary cells. May be associated also with poised promoters.

text: abcam

text: Abcam

text: ATCC

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: Rabbit polyclonal antibody raised against a peptide containing K79 di-methylation. Antibody Target: H3K79me2

characteristic: antibody antibodydescription

text: H3K79me2 is a mark of the transcriptional transition region - the region between the initiation marks (K4me3, etc) and the elongation marks (K36me3).

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: ATCC

text: M

text: std

text: Standard input signal for most experiments.

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

text: Broad_ChipSeq_A549_H3K79me2_EtOH_0.02pct

characteristic: title

text: 1 h with 0.02% Ethanol (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid

text: Histone acetyltransferase with sequence similarity to CBP (CREB-binding protein). Regulates transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation.

text: Bethyl Laboratories

text: Bethyl

text: WiCell Research Institute

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: Lonza

text: U

text: std

text: Osteobl/None/Input/std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina HiSeq 2000

text: Homo sapiens

text: Osteobl

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K9ac

text: Histone H3 (acetyl K9). As with H3K27ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases.

text: abcam

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K9ac

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

text: F

text: std

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K4me2


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal, ChIP grade. Antibody Target: H3K9me3

text: Histone H3 (tri methyl K9). Is associated with repressive heterochromatic state (silenced chromatin). NOTE CONTRAST to H3K9me1 which is associated with active and accessible regions.

text: abcam

text: Abcam

text: Lonza

characteristic: biomaterial provider

text: primary cell

characteristic: biomaterial type

text: U

characteristic: cell sex

text: endothelial cell of umbilical vein

characteristic: cell type

text: std

characteristic: controlid

text: HUVEC/None/Input/std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: donor id

text: Illumina HiSeq 2000

text: Homo sapiens

text: HUVEC

text: No special treatment or protocol applies

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2. Antibody Target: EZH2

characteristic: antibody antibodydescription

text: EZH2 (Enhancer of Zeste homolog 2, also designated Enx1 and SETDB1) is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein. It contains a SET domain that catalyzes the methylation of histone H3 at lysine 27 (Histone H3 Lys27 monomethylated, dimethylated and trimethylated). Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and Suz12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. EZH2 associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Deregulation of EZH2 is linked to a variety of cancers.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: Lonza

text: U

text: std

characteristic: control

characteristic: control description

text: HUVEC/None/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: HUVEC

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: abcam

text: Abcam

text: ATCC

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: softwareversion


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: ATCC

text: F

text: std

characteristic: control

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K27me3

text: Histone H3 (tri-methyl K27). Marks promoters that are silenced by Polycomb proteins in a given lineage; large domains are found at inactive developmental loci.

text: Millipore

text: DSMZ

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina Genome Analyzer IIx

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: DSMZ

text: M

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: softwareversion


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: Active Motif

text: Lonza

characteristic: biomaterial provider

text: U

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: HSMMtube/None/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

text: Homo sapiens

text: HSMMtube

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: WiCell Research Institute

text: M

text: std

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H4K20me1

text: Histone H4 (mono-methyl K20). Is associated with active and accessible regions. In mammals, PR-Set7 specifically catalyzes H4K20 monomethylation. NOTE CONTRAST to H3K20me3 which is associated with heterochromatin and DNA repair.

text: abcam

text: Abcam

text: Lonza

characteristic: biomaterial provider

text: U

characteristic: cell sex

text: std

characteristic: controlid

text: NH-A/Input/std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: softwareversion

text: NH-A


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: rabbit polyclonal. Antibody Target: H3K4me1

characteristic: antibody antibodydescription

text: Histone H3 (mono methyl K4). Is associated with enhancers, and downstream of transcription starts.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: Lonza

text: primary cell

characteristic: biomaterial type

text: F

text: fibroblast of dermis

characteristic: cell type

text: std

characteristic: control

text: Standard input signal for most experiments.

characteristic: control description

text: NHDF-Ad/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: donor id

text: Homo sapiens

text: NHDF-Ad

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: Rabbit polyclonal antibody raised against a peptide containing K79 di-methylation. Antibody Target: H3K79me2

text: H3K79me2 is a mark of the transcriptional transition region - the region between the initiation marks (K4me3, etc) and the elongation marks (K36me3).

text: Active Motif

text: Lonza

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

text: NHEK/Input/std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: NHEK

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: Lonza

text: M

text: std

characteristic: control

text: NHEK/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: softwareversion

text: NHEK


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: Active Motif

text: Lonza

characteristic: biomaterial provider

text: U

characteristic: cell sex

text: std

characteristic: control description

text: NHLF/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

text: NHLF

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: Rabbit polyclonal antibody raised against a peptide corresponding to the C-terminus of H2AZ. Antibody Target: H2AZ

characteristic: antibody antibodydescription

text: H2A.Z is a sequence variant of Histone H2A.

text: Millipore

text: Upstate (Millipore)

text: Lonza

text: U

text: std

characteristic: controlid

text: NHLF/Input/std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: NHLF

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: Lonza

text: U

text: std

characteristic: control

text: NHLF/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: softwareversion

text: NHLF


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: Active Motif

text: Lonza

characteristic: biomaterial provider

text: U

characteristic: cell sex

text: std

characteristic: control description

text: NH-A/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

text: NH-A

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: rabbit polyclonal. Antibody Target: H3K4me2

characteristic: antibody antibodydescription

text: Histone H3 (di methyl K4). Marks promoters and enhancers. Most CpG islands are marked by H3K4me2 in primary cells. May be associated also with poised promoters.

text: abcam

text: Abcam

text: Lonza

text: U

text: std

characteristic: controlid

text: NH-A/Input/std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: NH-A

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

text: rabbit polyclonal. Antibody Target: H3K9ac

text: Histone H3 (acetyl K9). As with H3K27ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: Lonza

text: U

text: std

characteristic: control

text: NH-A/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: softwareversion

text: NH-A


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: SRA accession

characteristic: antibody

text: abcam

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K4me1

text: No special treatment or protocol applies

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: antibody antibodydescription

text: Active Motif

text: S. Heimfeld Laboratory, FHCRC

text: F

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K79me2

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: rabbit polyclonal, ChIP grade. Antibody Target: H3K9me3

text: Histone H3 (tri methyl K9). Is associated with repressive heterochromatic state (silenced chromatin). NOTE CONTRAST to H3K9me1 which is associated with active and accessible regions.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

text: F

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: softwareversion

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K9me3


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H4K20me1

text: Histone H4 (mono-methyl K20). Is associated with active and accessible regions. In mammals, PR-Set7 specifically catalyzes H4K20 monomethylation. NOTE CONTRAST to H3K20me3 which is associated with heterochromatin and DNA repair.

text: abcam

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H4K20me1

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: Control

text: ATCC

characteristic: cell

text: epithelial cell line derived from a lung carcinoma tissue. (PMID: 175022), This line was initiated in 1972 by D.J. Giard, et al. through explant culture of lung carcinomatous tissue from a 58-year-old caucasian male. - ATCC, newly promoted to tier 2: not in 2011 analysis

characteristic: cell description

text: cancer

characteristic: cell karyotype

text: endoderm

characteristic: cell lineage

text: human

characteristic: cell organism

text: M

text: std

text: Standard input signal for most experiments.

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: title

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

text: Control

characteristic: antibody

text: ATCC

characteristic: biomaterial provider

text: immortalized cell line

characteristic: biomaterial type

text: cancer

text: endoderm

text: human

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina HiSeq 2000

characteristic: line

text: Homo sapiens

text: 1 h with 0.02% Ethanol (Myers)

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: rabbit polyclonal. Antibody Target: H3K4me3

characteristic: antibody antibodydescription

text: Histone H3 (tri methyl K4). Marks promoters that are active or poised to be activated.

characteristic: antibody targetdescription

text: ab8580; 07-473

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: 1)abcam; 2)Millipore

text: ATCC

text: immortalized cell line

text: M

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

characteristic: title

text: 1 h with 100 nM Dexamethasone (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: Rabbit polyclonal antibody raised against a peptide containing K79 di-methylation. Antibody Target: H3K79me2

text: H3K79me2 is a mark of the transcriptional transition region - the region between the initiation marks (K4me3, etc) and the elongation marks (K36me3).

text: Active Motif

text: ATCC

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: rabbit polyclonal. Antibody Target: H3K9ac

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: ATCC

text: M

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

text: 1 h with 0.02% Ethanol (Myers)

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: Recombinant protein corresponding to human SUZ12. Antibody Target: SUZ12

text: SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. This protein is component of the PRC2 complex, which methylates Lys-9 and Lys-27 residues of histone H3.

text: Millipore

text: ATCC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: replicate

characteristic: softwareversion

characteristic: title


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: Rabbit polyclonal antibody raised against a peptide corresponding to the C-terminus of H2AZ. Antibody Target: H2AZ

characteristic: antibody antibodydescription

text: H2A.Z is a sequence variant of Histone H2A.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: Upstate (Millipore)

text: ATCC

text: M

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: treatment

text: 1 h with 0.02% Ethanol (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: Active Motif

text: WiCell Research Institute

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

text: No special treatment or protocol applies

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: Upstate (Millipore)

text: S. Heimfeld Laboratory, FHCRC

text: F

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: replicate

characteristic: softwareversion

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H2A.Z

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

text: Active Motif

text: Lonza

characteristic: biomaterial provider

text: U

text: std

text: NHLF/Input/std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

text: NHLF


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

text: This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2. Antibody Target: EZH2

characteristic: antibody antibodydescription

text: EZH2 (Enhancer of Zeste homolog 2, also designated Enx1 and SETDB1) is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein. It contains a SET domain that catalyzes the methylation of histone H3 at lysine 27 (Histone H3 Lys27 monomethylated, dimethylated and trimethylated). Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and Suz12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. EZH2 associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Deregulation of EZH2 is linked to a variety of cancers.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

text: Lonza

text: F

characteristic: cell sex

text: std

characteristic: control

text: NHDF-Ad/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

text: NHDF-Ad

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

text: rabbit polyclonal, ChIP grade. Antibody Target: H3K9me3

text: Histone H3 (tri methyl K9). Is associated with repressive heterochromatic state (silenced chromatin). NOTE CONTRAST to H3K9me1 which is associated with active and accessible regions.

text: abcam

characteristic: antibody vendorname

text: Abcam

text: DSMZ

text: immortalized cell line

characteristic: biomaterial type

text: M

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: line

text: Homo sapiens

characteristic: replicate

characteristic: softwareversion

characteristic: title


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

characteristic: antibody antibodydescription

text: Histone H3 (acetyl K9). As with H3K27ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

text: Abcam

text: DSMZ

characteristic: biomaterial provider

text: M

text: std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

text: abcam

characteristic: antibody vendorname

text: Abcam

text: Lonza

text: F

characteristic: cell sex

text: std

characteristic: control

text: Standard input signal for most experiments.

characteristic: control description

characteristic: controlid

text: NHDF-Ad/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

text: NHDF-Ad

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: antibody

characteristic: antibody antibodydescription

text: Active Motif

text: Lonza

text: F

text: std

text: NHDF-Ad/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: replicate

characteristic: softwareversion

text: NHDF-Ad

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

characteristic: antibody vendorname

text: Lonza

characteristic: biomaterial provider

text: U

text: std

text: HUVEC/Input/std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

text: HUVEC


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Millipore

text: Upstate (Millipore)

text: Lonza

text: U

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: HUVEC/Input/std

characteristic: controlid

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

text: HUVEC

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

characteristic: antibody antibodydescription

text: Active Motif

text: Lonza

text: U

text: std

text: HMEC/Input/std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: replicate

characteristic: softwareversion

text: HMEC

characteristic: title


text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Input

text: Control signal which may be subtracted from experimental raw signal before peaks are called.

characteristic: antibody description

text: DSMZ

characteristic: biomaterial provider

characteristic: cell

text: T cell leukemia with Notch mutation

characteristic: cell description

text: cancer

characteristic: cell karyotype

text: mesoderm

characteristic: cell lineage

text: human

characteristic: cell organism

text: M

text: std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina Genome Analyzer IIx

characteristic: labversion

text: Homo sapiens


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K27ac

characteristic: antibody antibodydescription

text: Histone H3 (acetyl K27). As with H3K9ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation has can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: abcam

characteristic: antibody vendorname

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

text: F

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K27ac

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Rabbit polyclonal. Antibody Target: SIRT6

text: A synthetic peptide made to an internal region of the human SIRT6 protein

text: abcam

text: Abcam

text: ATCC

characteristic: biomaterial provider

text: F

text: std

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina Genome Analyzer IIx

characteristic: labversion description

text: Homo sapiens

characteristic: softwareversion

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K4me3

characteristic: antibody antibodydescription

text: Histone H3 (tri methyl K4). Marks promoters that are active or poised to be activated.

characteristic: antibody targetdescription

text: ab8580; 07-473

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: 1)abcam; 2)Millipore

text: ATCC

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: treatment

text: 1 h with 0.02% Ethanol (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: rabbit polyclonal. Antibody Target: H3K36me3

text: Histone H3 (tri-methyl K36). Marks regions of RNAPII elongation, including coding and non-coding transcripts.

text: Specific for histone H3 tri methylated at lysine 36, weakly reacts with H3K36me2. Marks regions of RNAPII elongation, including coding and non-coding transcripts.

text: abcam

text: Abcam

text: S. Heimfeld Laboratory, FHCRC

characteristic: biomaterial provider

text: primary cell

characteristic: biomaterial type

text: F

text: CD14-positive monocyte

characteristic: cell type

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: donor id

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: Broad_ChipSeq_Monocytes-CD14+_RO01746_H3K36me3

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid

characteristic: antibody antibodydescription

text: Ring finger protein 2 (RNF2) is a polycomb group (PcG) protein. RNF2 has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2).

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: ATCC

text: F

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: softwareversion

characteristic: title

text: No special treatment or protocol applies


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: NCoR

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid Antibody Target: NCOR1

text: The nuclear receptor corepressor protein (NCoR) mediates gene repression by interacting with nuclear receptors. NCoR mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.

text: Bethyl Laboratories

text: Bethyl

text: ATCC

characteristic: biomaterial provider

text: F

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

text: PCAF

characteristic: antibody

characteristic: antibody antibodydescription

text: PCAF (P300/CBP-associated factor) is a histone acetyltransferase (HAT) identified as a factor that associates with P300/CBP, a transcriptional coactivator of nuclear hormone receptors and other transcription factors.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: ATCC

text: F

characteristic: cell sex

text: std

characteristic: control

text: Standard input signal for most experiments.

characteristic: control description

text: ChipSeq

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

text: Homo sapiens


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated. Antibody Target: CBX2

text: Chromobox protein homolog 2 is a component of the polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P19474]

text: Bethyl Laboratories

text: Bethyl

text: ATCC

characteristic: biomaterial provider

text: F

text: std

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: softwareversion

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: Mouse monoclonal IgG, raised against recombinant CBX3 of human origin. Antibody Target: CBX3

characteristic: antibody antibodydescription

text: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Santa Cruz Biotech

text: Santa Cruz Biotechnology

text: ATCC

text: F

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CBX8

text: CBX8 is part of the polycomb group of proteins that are important in embryogenesis and human tumorigenesis and regulates a number of genes involved in cell growth and survival. There are at least 5 CBX proteins in mammals. CBX proteins associate with the core polycomb repressive complex 1 (PRC1) that functions to maintain the transcriptionally repressive state of genes during development.

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: ATCC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

text: Homo sapiens


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

characteristic: antibody antibodydescription

text: BHC110/LSD1 is a histone demethylase and a component of several histone deacetylase complexes. BHC110/LSD1 is able to specifically catalyze the demethylation of Lys4 of histone H3. As part of histone deacetylase complexes BHC110/LSD1 functions as a corepressor of transcription.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Bethyl Laboratories

text: Bethyl

text: ATCC

text: F

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: softwareversion

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: HDAC6

text: Histone deacetylase 6 (HDAC6) is a class II histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminus of core histones. HDAC6 has also been identified as a cytoplasmic deacetylase that acts on tubulin and HSP90 to influence cell motility. Recently HDAC6 has been found to be involved in the stress response as a component of cytoplasmic stress granules.

text: Bethyl Laboratories

characteristic: antibody vendorname

text: Bethyl

text: WiCell Research Institute

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: This SAP30 antibody (pAb) was raised against recombinant full length human SAP30 protein. Antibody Target: SAP30

characteristic: antibody antibodydescription

text: SAP30, also known asSin3A-associated protein, 30kDa, is part of the SIN3 corepressor complex, that also includes SIN3, SAP18,HDAC1,HDAC2,RbAp46andRbAp48. SAP30 is involved in the functional recruitment of the Sin3-histone deacetylase complex to a specific subset of N-CoR corepressor complexes.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

text: WiCell Research Institute

text: M

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Illumina Genome Analyzer IIx

text: Homo sapiens


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Recombinant protein corresponding to human SUZ12. Antibody Target: SUZ12

text: SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. This protein is component of the PRC2 complex, which methylates Lys-9 and Lys-27 residues of histone H3.

text: Millipore

characteristic: antibody vendorname

text: WiCell Research Institute

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina Genome Analyzer IIx

characteristic: labversion description

text: Homo sapiens

characteristic: softwareversion

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: Rabbit polyclonal, epitope mapping at the N-terminus of CBP of human origin. Antibody Target: CREBBP

characteristic: antibody antibodydescription

text: Rabbit polyclonal, epitope mapping at the N-terminus of CBP of human origin. Antibody Target: CBP

text: CBP is a histone acetyl transferase that promotes transcription. CBP is recruited by a variety of transcription factors to promoters and enhancers.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Santa Cruz Biotech

text: Santa Cruz Biotechnology

text: ATCC

text: F

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina Genome Analyzer IIx

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: No special treatment or protocol applies

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CHD1

text: CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation. Alternate names for CHD1 include chromodomain-helicase-DNA-binding protein 1, ATP-dependent helicase CHD1, and DKFZp686E2337.

text: Bethyl Laboratories

characteristic: antibody vendorname

text: ATCC

characteristic: biomaterial provider

text: F

characteristic: cell sex

text: std

characteristic: control

text: Standard input signal for most experiments.

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2. Antibody Target: EZH2

characteristic: antibody antibodydescription

text: EZH2 (Enhancer of Zeste homolog 2, also designated Enx1 and SETDB1) is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein. It contains a SET domain that catalyzes the methylation of histone H3 at lysine 27 (Histone H3 Lys27 monomethylated, dimethylated and trimethylated). Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and Suz12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. EZH2 associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Deregulation of EZH2 is linked to a variety of cancers.

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Active Motif

text: ATCC

text: F

text: std

text: ChipSeq

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: softwareversion

characteristic: title


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: rabbit polyclonal. Antibody Target: H3K27me3

text: Histone H3 (tri-methyl K27). Marks promoters that are silenced by Polycomb proteins in a given lineage; large domains are found at inactive developmental loci.

text: Millipore

characteristic: antibody vendorname

text: ATCC

text: M

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K27ac

characteristic: antibody antibodydescription

text: Histone H3 (acetyl K27). As with H3K9ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation has can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases.

characteristic: antibody targetdescription

text: abcam

text: Abcam

text: ATCC

characteristic: biomaterial provider

text: immortalized cell line

characteristic: biomaterial type

text: M

characteristic: cell sex

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Illumina HiSeq 2000

characteristic: line

text: Homo sapiens

text: 1 h with 0.02% Ethanol (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Rabbit polyclonal antibody raised against a peptide corresponding to the C-terminus of H2AZ. Antibody Target: H2AZ

text: H2A.Z is a sequence variant of Histone H2A.

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: Upstate (Millipore)

text: WiCell Research Institute

text: M

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: organism

characteristic: replicate

characteristic: softwareversion

characteristic: title


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

text: Millipore

text: Upstate (Millipore)

text: ATCC

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

characteristic: labversion description

text: Homo sapiens

characteristic: treatment

text: 1 h with 100 nM Dexamethasone (Myers)

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: CTCF

text: rabbit polyclonal. Antibody Target: CTCF

text: Rabbit polyclonal. Antibody Target: CTCF

text: CTCF zinc finger transcription factor. A sequence specific DNA binding protein that functions as an insulator, blocking enhancer activity. It has also been suggested to block the spreading of chromatin structure in certain instances.

characteristic: antibody vendorid

text: Millipore

characteristic: antibody vendorname

text: ATCC

text: M

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

characteristic: datatype description

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: organism

characteristic: replicate

text: 1 h with 0.02% Ethanol (Myers)


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

text: CTCF

characteristic: antibody

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

text: Millipore

text: ATCC

characteristic: biomaterial provider

text: M

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: labversion

text: Illumina HiSeq 2000

text: Homo sapiens

characteristic: softwareversion

characteristic: title

text: 1 h with 100 nM Dexamethasone (Myers)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: Rabbit Polyclonal. Antibody Target: P300

characteristic: antibody vendorid

text: Santa Cruz Biotech

characteristic: antibody vendorname

text: Santa Cruz Biotechnology

text: ATCC

text: F

text: std

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: treatment description


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: RBBP5

characteristic: antibody antibodydescription

text: Retinoblastoma binding protein 5 (RbBP5) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. RbBP5 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, ASH2L,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX. RbBP5 is also one of many proteins that bind the Retinoblastoma tumor suppressor protein, pRb. Alternate names for RbBP5 are RBQ3 and SWD1.

characteristic: antibody targetdescription

text: Bethyl Laboratories

text: WiCell Research Institute

characteristic: biomaterial provider

text: M

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Homo sapiens

characteristic: organism

characteristic: replicate


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: rabbit polyclonal, ChIP grade. Antibody Target: H3K9me3

text: Histone H3 (tri methyl K9). Is associated with repressive heterochromatic state (silenced chromatin). NOTE CONTRAST to H3K9me1 which is associated with active and accessible regions.

characteristic: antibody vendorid

text: abcam

text: Abcam

text: WiCell Research Institute

text: stem cell

characteristic: biomaterial type

text: M

characteristic: cell sex

text: std

characteristic: control

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: line

text: Homo sapiens

characteristic: softwareversion

characteristic: title

text: No special treatment or protocol applies


text: ENCODE DCC

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

characteristic: antibody

text: Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: PLU1

characteristic: antibody antibodydescription

text: JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer. Alternative names for JARID1B include retinoblastoma-binding protein 2 homolog 1, RBP2-H1, cancer/testis antigen 31, CT31, PLU-1, PUT1, and KDM5B.

characteristic: antibody targetdescription

text: YangShi lab

characteristic: antibody vendorname

text: ATCC

text: F

text: std

text: Standard input signal for most experiments.

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Homo sapiens

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

text: immortalized

characteristic: age

text: Immortal cells

characteristic: age description

text: rabbit polyclonal. Antibody Target: H3K4me1

text: Histone H3 (mono methyl K4). Is associated with enhancers, and downstream of transcription starts.

characteristic: antibody vendorid

text: Abcam

text: Weissman lab

characteristic: biomaterial provider

text: MEL

characteristic: cell

text: Leukemia (K562 analog)

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: IgG-rab

text: Input signal from Normal Rabbit IgG ChIP-seq.

text: MEL/None/Input/IgG-rab

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

characteristic: labversion

text: Mus musculus

characteristic: organism

text: MEL

text: Unknown strain origin

characteristic: strain description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

text: immortalized

text: Immortal cells

characteristic: antibody

text: rabbit monoclonal. Antibody Target: H3K27me3

characteristic: antibody antibodydescription

text: Histone H3 (tri-methyl K27) marks repressed chromatin regions

characteristic: antibody targetdescription

text: Cell Signaling

characteristic: antibody vendorname

text: Weissman lab

text: MEL

text: Leukemia (K562 analog)

text: mouse

text: M

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Stanford-m

text: Snyder - Stanford University

text: Mus musculus

text: MEL

text: Unknown strain origin

text: Stanford_ChipSeq_MEL_H3K27me3B_DMSO_2.0pct_std

characteristic: title

characteristic: treatment

text: 5 d with 2% Dimethyl sufloxide (DMSO) (Weissman)

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC last update

text: live

text: Generic

characteristic: NCBI submission package

characteristic: age

text: Embryonic day 0 (stem cell)

characteristic: age description

text: Input

text: Control signal which may be subtracted from experimental raw signal before peaks are called.

characteristic: antibody description

text: Santos lab

characteristic: biomaterial provider

characteristic: cell

text: mouse embryonic stem cell line E14

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

text: Mus musculus

characteristic: organism

characteristic: replicate

characteristic: strain

text: The mice have yellow coats and late onset severe vacuolation in brain (700+ days). Inbred strain used as a control group to compare with null PrP mice.

characteristic: strain description

text: Stanford_ChipSeq_ES-E14_Input_std (superseded by GSE136425)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: SRA accession

text: immortalized

text: Immortal cells

text: Input

characteristic: antibody

text: Weissman lab

text: MEL

text: Leukemia (K562 analog)

text: mouse

text: M

text: IgG-rab

characteristic: control

characteristic: control description

text: MEL/None/Input/IgG-rab

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Stanford-m

text: Snyder - Stanford University

text: Mus musculus

text: MEL

text: Unknown strain origin

text: Stanford_ChipSeq_MEL_Input_IgG-rab (superseded by GSE94229)

characteristic: title

characteristic: treatment description


text: ENCODE DCC

text: live

text: Generic

characteristic: NCBI submission package

text: immortalized

characteristic: age

text: Immortal cells

characteristic: age description

text: rabbit polyclonal, ChIP grade. Antibody Target: H3K9me3

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Abcam

characteristic: antibody vendorname

text: Weissman lab

characteristic: biomaterial provider

text: MEL

characteristic: cell

text: Leukemia (K562 analog)

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

text: Mus musculus

characteristic: organism

text: MEL

text: Unknown strain origin

text: Stanford_ChipSeq_MEL_H3K9me3_DMSO_2.0pct_std

characteristic: treatment


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

text: immortalized

text: Immortal cells

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K36me3

text: Histone H3 (tri-methyl K36) marks actively transcribed chromatin regions

text: Cell Signaling

text: Weissman lab

text: MEL

text: Leukemia (K562 analog)

text: mouse

text: M

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Stanford-m

text: Snyder - Stanford University

text: Mus musculus

text: MEL

text: Unknown strain origin

characteristic: strain description

text: Stanford_ChipSeq_MEL_H3K36me3B_DMSO_2.0pct_std

characteristic: title

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

text: live

text: Generic

characteristic: age

text: Embryonic day 0 (stem cell)

characteristic: age description

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Abcam

characteristic: antibody vendorname

text: Santos lab

characteristic: biomaterial provider

characteristic: cell

text: mouse embryonic stem cell line E14

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: std

text: Standard input signal for most experiments.

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

characteristic: labversion

text: Mus musculus

characteristic: organism

characteristic: strain

text: No special treatment or protocol applies


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

characteristic: age

text: Embryonic day 0 (stem cell)

characteristic: antibody

text: Histone H3 (tri methyl K9). Is associated with repressive heterochromatic state (silenced chromatin). NOTE CONTRAST to H3K9me1 which is associated with active and accessible regions.

text: Abcam

text: Santos lab

text: mouse embryonic stem cell line E14

text: mouse

text: M

text: std

characteristic: control

characteristic: control description

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Stanford-m

text: Snyder - Stanford University

text: Mus musculus

characteristic: strain description

characteristic: title

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

text: live

text: Generic

text: immortalized

text: Immortal cells

characteristic: age description

text: Weissman lab

characteristic: biomaterial provider

text: MEL

characteristic: cell

text: Leukemia (K562 analog)

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: IgG-rab

text: Input signal from Normal Rabbit IgG ChIP-seq.

text: MEL/None/Input/IgG-rab

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

characteristic: labversion

text: Mus musculus

characteristic: organism

text: MEL

text: Unknown strain origin

text: Stanford_ChipSeq_MEL H3K27me3 IgG-rab (was Stanford_ChipSeq_MEL_H3K27ac_IgG-rab) (superseded by GSE94230)


text: ENCODE DCC

characteristic: INSDC first public

characteristic: INSDC last update

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

text: immortalized

characteristic: age

text: Immortal cells

characteristic: antibody

text: rabbit polyclonal. Antibody Target: H3K4me3

characteristic: antibody antibodydescription

text: Histone H3 (tri methyl K4). Marks promoters that are active or poised to be activated.

characteristic: antibody targetdescription

text: ab8580; 07-473

characteristic: antibody vendorid

text: 1)Abcam; 2)Millipore

characteristic: antibody vendorname

text: Weissman lab

text: MEL

text: Leukemia (K562 analog)

text: mouse

text: M

text: IgG-rab

characteristic: control

characteristic: control description

text: MEL/None/Input/IgG-rab

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Stanford-m

text: Snyder - Stanford University

text: Mus musculus

text: MEL

text: Unknown strain origin

text: Stanford_ChipSeq_MEL_H3K4me3_IgG-rab (superseded by GSE94231)


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

text: live

text: Generic

text: immortalized

text: Immortal cells

characteristic: age description

text: ab8580; 07-473

text: 1)Abcam; 2)Millipore

text: Weissman lab

characteristic: biomaterial provider

text: MEL

characteristic: cell

text: Leukemia (K562 analog)

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

characteristic: labversion

text: Mus musculus

characteristic: organism

text: MEL

text: Unknown strain origin

characteristic: strain description

text: Stanford_ChipSeq_MEL_H3K4me3_DMSO_2.0pct_std (superseded by GSE94233)

characteristic: title

characteristic: treatment

text: 5 d with 2% Dimethyl sufloxide (DMSO) (Weissman)

characteristic: treatment description


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC last update

characteristic: INSDC secondary accession

text: live

characteristic: INSDC status

text: Generic

characteristic: NCBI submission model

characteristic: NCBI submission package

characteristic: SRA accession

text: immortalized

characteristic: age

text: Immortal cells

characteristic: antibody

characteristic: antibody antibodydescription

characteristic: antibody targetdescription

characteristic: antibody vendorid

text: Abcam

characteristic: antibody vendorname

text: Weissman lab

text: MEL

text: Leukemia (K562 analog)

text: mouse

text: M

text: IgG-rab

characteristic: control

characteristic: control description

text: MEL/None/Input/IgG-rab

characteristic: controlid

text: ChipSeq

characteristic: datatype

text: Chromatin IP Sequencing

text: Stanford-m

text: Snyder - Stanford University

text: Mus musculus

text: MEL

text: Unknown strain origin


characteristic: External Id

text: ENCODE DCC

characteristic: INSDC center name

characteristic: INSDC first public

text: live

text: Generic

text: Embryonic day 0 (stem cell)

characteristic: age description

text: ab8580; 07-473

text: 1)Abcam; 2)Millipore

text: Santos lab

characteristic: biomaterial provider

characteristic: cell

text: mouse embryonic stem cell line E14

characteristic: cell description

text: mouse

characteristic: cell organism

text: M

characteristic: cell sex

text: std

text: ChipSeq

text: Chromatin IP Sequencing

characteristic: datatype description

text: Stanford-m

characteristic: lab

text: Snyder - Stanford University

characteristic: lab description

characteristic: labversion

text: Mus musculus

characteristic: organism

characteristic: strain

text: The mice have yellow coats and late onset severe vacuolation in brain (700+ days). Inbred strain used as a control group to compare with null PrP mice.

characteristic: strain description

characteristic: title

characteristic: treatment description