text: bread wheat

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007588 - Accession Name = 'Aus28057'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: India

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

characteristic: submission description

characteristic: submission identifier

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf


status: PUBLIC

characteristic: SRA accession

text: bread wheat

characteristic: common name

text: MIRONOVSKAJA 808

characteristic: cultivar

text: AWCC

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-002752 - Accession Name = 'MIRONOVSKAJA 808'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: winter wheat

characteristic: ecotype

text: Russia

characteristic: geographic location (country and/or sea)

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

characteristic: submission title

text: leaf

characteristic: tissue type

characteristic: variety

type: has member

Eduard Akhunov

Address: 1712 Claflin Road, Department of Plant Pathology, Kansas State University, Manhattan, KS 66506, USA

Fei He

FirstName: Fei

LastName: He


text: 1962 Indiana, United States by Patterson, F., Purdue University; Schafer, J., USDA-ARS; Gallun, R., USDA-ARS

characteristic: collected by

text: bread wheat

text: Knox 62

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004469 - Accession Name = 'Knox 62'; Remarks = 'Soft red winter wheat. Similar to Knox, but contains resistance to Hessian fly.'; Released = '1962'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Knox*5/8/Kawvale/5/Fultz/Hungarian//Illinois No. 1 (W38)/3/Wabash/4/Fairfield/6/3*Trumbull//Hope/Hussar/7/Knox sib/5/Fairfield/4/PI 94587//Fultz/Hungarian/3/Fultz/Hungarian '

characteristic: description

text: 2 week old

characteristic: dev stage

text: winter wheat

text: USA

text: CItr 13701

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:CItr 13701

text: subsp. aestivum

text: leaf

text: :Knox 62;:Purdue 55103-1-16;:CI 13701


text: 08/20/2003 Badakhshoni Kuhi, Tajikistan by Street, K., Int. Center for Agriculture Research in the Dry Areas; Muminshoeva, Z., Tajik Agricultural Academy; Kasymov, F., Tajikistan Agricultural Academy; Narzulloev, T., Tajikistan Agricultural Academy

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001916 - Accession Name = 'TJK03-196'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '37.44055556,71.60833333,2218'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Tajikistan

text: Badakhshoni Kuhi;24 km out of Khorog along the Gunt river valley on south east side of river. Shord Village

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 639387

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 639387

text: subsp. aestivum

characteristic: submission description

characteristic: submission identifier

text: leaf

text: :TJK03-196;:ICC 137032;USA126:NGRL 699;:KS 0803


characteristic: SRA accession

text: South Moravia, Czech Republic by Research Institute of Cereal Crops

text: bread wheat

characteristic: common name

text: KM 780-92

characteristic: cultivar

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-001559 - Accession Name = 'KM 780-92'; Remarks = 'Spike type: NS-multispikelet.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Czech Republic

text: PI 574320

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 574320

text: subsp. aestivum

text: leaf

text: :KM 780-92;:NSGC 1330


text: bread wheat

text: clear white+yr5+yr15+2NS+gpc+lr34

text: exome sequences of ExomeCapture-WSC-4-1 - Accession Name = 'clear white+yr5+yr15+2NS+gpc+lr34'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Breeding line'

text: 2 week old

text: spring wheat

text: USA

characteristic: geographic location (country and/or sea)

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: leaf


text: bread wheat

text: RUMANIA 3

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002946 - Accession Name = 'RUMANIA 3'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

text: Romania

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission title

text: leaf

characteristic: tissue type

characteristic: variety


text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000574 - Accession Name = 'Aus30299/2*Annuello*4'; Remarks = 'BC2F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus30299/2*Annuello'

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

text: leaf

text: Aus30299 = DVERD_2/AE.SQUARROSA (1027)


text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000524 - Accession Name = 'Aus34450/annuello*21'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus34450/annuello'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission description

characteristic: submission identifier

text: leaf

text: Aus34450 = 68.111/RGB-U//WARD/3/FGO/4/RABI/5/AE.SQUARROSA (629)


characteristic: SRA accession

text: Philippines by Director of Agriculture

characteristic: collected by

text: bread wheat

characteristic: common name

text: Saracen

text: exome sequences of ExomeCapture-Cltr-4175 - Accession Name = 'Saracen'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Philippines

text: northern portion of P.I.

characteristic: geographic location (region and locality)

text: CITR 4175

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: CITR 4175

text: subsp. aestivum

text: leaf

text: :Saracen;:Candeal;:AUS 6980;:CI 4175


text: Turkmenistan by. DONATED 12/30/1959 by N.I. Vavilov Institute of Plant Industry

text: bread wheat

text: Kysyldzha

characteristic: cultivar

text: exome sequences of ExomeCapture-WSC-7-1 - Accession Name = 'Kysyldzha'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Turkmenistan

characteristic: geographic location (country and/or sea)

text: PI 262611

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 262611

text: subsp. aestivum

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf

text: :Kysyldzha;:WIR 40321


text: 1948 Central Bohemia, Czech Republic by Celechovice. DONATED 09/05/1978 by Lekes, J., Research Institute for Cereal Growing

text: bread wheat

text: Detenicka Cervena Vouska

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-003484 - Accession Name = 'Detenicka Cervena Vouska'; Remarks = '.'; Released = '1948'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'selection from Kraffts Siegerlander'

text: 2 week old

text: spring wheat

text: Czech Republic

text: PI 428644

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 428644

characteristic: specimen voucher

text: subsp. aestivum

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf

text: :Detenicka Cervena Vouska;:C1-0053


text: bread wheat

text: SALAMANCA 2

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007518 - Accession Name = 'SALAMANCA 2'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

text: spring wheat

text: Spain

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: sub species

characteristic: submission title

text: leaf

characteristic: tissue type


text: bread wheat

text: BOINTA 2004

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002153 - Accession Name = 'BOINTA 2004'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: Argentina

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

characteristic: submission description

text: leaf

characteristic: variety


characteristic: SRA accession

text: by Macindoe, S., Glen Innes Experiment Farm. COLLECTED Egypt by. DONATED 1944 by Ausemus, E., USDA-Bureau of Plant Industry

characteristic: collected by

text: bread wheat

characteristic: common name

text: Red Egyptian

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001797 - Accession Name = 'Red Egyptian'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Egypt

text: CItr 12345

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:CItr 12345

text: subsp. aestivum

characteristic: submission identifier

text: leaf

text: :Red Egyptian;:C 12081;:CI 12345


text: bread wheat

text: STEPINATCHKA

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-003075 - Accession Name = 'STEPINATCHKA'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Russia

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: bread wheat

text: AVS

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-000719 - Accession Name = 'Aus29672/2*Annuello*9'; Remarks = 'BC2F6 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus29672/2*Annuello'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Australia

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf

text: Aus29672 = KAPUDE/AE.SQUARROSA (385)


text: Oregon, United States by Kronstad, W., Oregon State University

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004166 - Accession Name = '908164'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Topo 'S'/Narino 59*2//Budifen/3/Bobwhite 'S'/4/Pumafen//Ciano 'S'/Gallo'

characteristic: description

text: 2 week old

text: spring wheat

text: USA

text: PI 620694

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 620694

characteristic: specimen voucher

text: subsp. aestivum

text: leaf

text: :908164;USA126:NSGC 8124


text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004167 - Accession Name = '908237'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'CARGL62//TJB368-251/Buckbuck'

text: 2 week old

text: spring wheat

text: USA

text: PI 620674

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 620674

text: subsp. aestivum

characteristic: sub species

characteristic: submission title

text: leaf

characteristic: tissue type

text: :908237;USA126:NSGC 8104


text: bread wheat

text: Emmit

text: AVS

text: exome sequences of ExomeCapture-DAS5-EMMIT - Accession Name = 'Emmit'; Remarks = 'Hard white sptring wheat'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: AVS:.

text: subsp. aestivum

characteristic: submission description

text: leaf


characteristic: SRA accession

text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000330 - Accession Name = 'Aus33408/yitpi*8'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus33408/yitpi'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf

text: Aus33408 = DOY1/AE.SQUARROSA (322)

characteristic: variety


text: bread wheat

characteristic: common name

text: DAGHESTAN 171

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002263 - Accession Name = 'DAGHESTAN 171'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Russia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

text: leaf


text: bread wheat

characteristic: cultivar

text: AVS

text: exome sequences of ExomeCapture-DAS5-000491 - Accession Name = 'Aus34436/annuello*14'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus34436/annuello'

text: 2 week old

text: spring wheat

text: Australia

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf

text: Aus34436 = DOY1/AE.SQUARROSA (511)


text: 2001 New York, United States by Sorrells, M., Cornell University; Bergstrom, G., Cornell University; Benscher, D., Cornell University

characteristic: collected by

text: bread wheat

text: Richland

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-004571 - Accession Name = 'Richland'; Remarks = 'Grain yield similar to Caledonia and averaged 6% higher grain yield than Geneva in 5 yrs. of regional testing in New York site. Test weight similar to Geneva and averaged 78.1 kg h1, 1 kg/h1 above Caledonia over 5 yrs. Similar in height to Geneva and averages 11 cm taller than Caledonia. Lodging resistance and winter hardiness similar to Geneva and slightly superior to Caledonia. Milling and baking characteristics are among the best for soft white winter wheats as deteremined by the USDA Soft Wheat Quality Lab., Wooster, OH. Susceptible to preharvest sprouting. Days to heading and maturity similar to most soft white winter cvs. grown in New York except Geneva which is 2 days earlier to reach anthesis. Stems and leaves yellow-green at booting and hollow white stems at maturity. At booting the flag leaf is erect and twisted and the stems have a waxy bloom. Spikes dense, tapering, and awnletted. Glumes tan, medium long, wide and have a square shoulder and an obtuse beak. Kernels soft white, ovate, have rounded cheeks and short brush, and a narrow, shallow crease. The mass of 1000 kernels averages 35g. Moderately resistant to prevalent races of loose smut (Ustilago tritici) and highly resistant to prevalent races of Powdery mildew (Erysiphe graminis). Susceptible to fusarium head blight (Fusarium graminearum), and highly resistant to wheat spindle streak, mosaic virus and soil borne mosaic virus.'; Released = '2001'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'selection from a composite population that was composed of the following F1 hybrids: 79052-'Kleiber' (PI383394)/'Houser'//Houser; 79053-Houser//Kleiber (PI383394)/Houser; 79054-Houser//Houser/Kleiber (PI345527); 79055-Houser/Kleiber (PI345527)//Houser; 79056-Houser//Houser/Kleiber (PI383394); 79057-Houser/Kleiber (PI383394)//Houser; 59076-Kleiber (PI383394)/Houser//'Geneva'; 59077-Houser/Kleiber (PI383394)//Geneva'

text: 2 week old

text: winter wheat

characteristic: ecotype

text: USA

text: PI 632399

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 632399

text: subsp. aestivum

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf


text: Nebraska, United States by Graybosch, R., USDA-ARS

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004527 - Accession Name = 'NWX008075'; Remarks = 'Winter habit waxy wheat (amylose-free).'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Bai Huo/Kanto 107//Ike'

characteristic: description

text: 2 week old

text: F

text: USA

text: PI 619379

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 619379

text: subsp. aestivum

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf

text: :NWX008075;USA126:NSGC 8778


text: bread wheat

text: BAROVITSCHKAJA

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002099 - Accession Name = 'BAROVITSCHKAJA'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Russia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

characteristic: submission title

text: leaf


text: Israel by Institute of Field & Garden Crops. DONATED 04/13/1987 by Konzak, C., Washington State University

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001016 - Accession Name = '1117/83'; Remarks = 'T. dicoccoides (strain G-25) used to obtain higher protein and stripe rust resistance.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Nursi/T. dicoccoides (strain G-25)//708-26/3/Cajeme-71'

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Israel

text: PI 508391

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 508391

text: subsp. aestivum

text: leaf

characteristic: tissue type


characteristic: SRA accession

text: bread wheat

text: RUMANIA 12

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002944 - Accession Name = 'RUMANIA 12'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Romania

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission description

text: leaf

characteristic: variety


text: 1918 Uruguay by. DONATED 09/28/1950 by Estacao de Melhoramento de Plantas

text: bread wheat

characteristic: common name

text: Americano 44D

characteristic: cultivar

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004229 - Accession Name = 'Americano 44D'; Remarks = 'Solid stem.'; Released = '1918'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'selection from landrace'

text: 2 week old

text: spring wheat

text: Uruguay

text: PI 191937

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 191937

text: subsp. aestivum

characteristic: submission identifier

text: leaf

text: :Americano 44D;:3329;:10130


text: 04/30/1924 Rumphi, Malawi by Shantz, H., United States Department of Agriculture

characteristic: collected by

text: bread wheat

text: exome sequences of ExomeCapture-PI-61693 - Accession Name = '294'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '-10.6,34.11666667,1167'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Malawi

characteristic: geographic location (country and/or sea)

text: Rumphi;Livingstonia; highlands above Nyasaland

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 61693

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 61693

text: subsp. aestivum

text: leaf

text: :294;:CItr 7697;:CI 7697


text: bread wheat

text: KZYL-CAS

text: AWCC

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-002649 - Accession Name = 'KZYL-CAS'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

text: Russia

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: bread wheat

text: SMYRNA 8

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007756 - Accession Name = 'SMYRNA 8'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: spring wheat

characteristic: ecotype

text: Turkey

text: (Isparta);Aidin railway locations between Sokia (Aydin) and Baladiz (Isparta)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

characteristic: submission title

text: leaf


characteristic: SRA accession

text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000826 - Accession Name = 'Aus29671/2*Annuello*6'; Remarks = 'BC2F6 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus29671/2*Annuello'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

characteristic: submission description

text: leaf

characteristic: tissue type

text: Aus29671 = GARZA/BOY//AE.SQUARROSA (165)

characteristic: variety


text: bread wheat

characteristic: common name

text: MAGPIE S

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002705 - Accession Name = 'MAGPIE S'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Mexico

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf


text: bread wheat

text: GAZA 1

text: AWCC

characteristic: culture collection

text: exome sequences of ExomeCapture-WATKINS-007325 - Accession Name = 'GAZA 1'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

text: spring wheat

text: Egypt

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf


text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000875 - Accession Name = 'Aus29669/2*Annuello*5'; Remarks = 'BC2F6 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus29669/2*Annuello'

text: 2 week old

text: spring wheat

text: Australia

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf

text: Aus29669 = GAE.SQUARROSA (890)


text: bread wheat

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002811 - Accession Name = 'NW59A'; Remarks = 'Red'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: winter wheat

characteristic: ecotype

text: Nepal

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: bread wheat

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007561 - Accession Name = 'Aus28028'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: India

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: leaf


characteristic: SRA accession

text: South Australia, Australia by Driscoll, C., Waite Agricultural Research Institute; University of New South Wales

characteristic: collected by

text: bread wheat

text: Cornerstone

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-003328 - Accession Name = 'Cornerstone'; Remarks = 'Chromosomal male-sterile germplasm.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Federation/Pitic 62//Pitic 62-3/Condor = Federation monosomic 4A/Pitic 62-irradiated//Pitic 62/Condor'

text: 2 week old

text: spring wheat

text: Australia

text: PI 409014

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 409014

text: subsp. aestivum

characteristic: submission title

text: leaf

text: :Cornerstone


text: Graubunden, Switzerland by Popow, G., Swiss Federal Research Sta. for Agronomy

text: bread wheat

text: exome sequences of ExomeCapture-WSC-4-4 - Accession Name = '2045A'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '46.81666667,10.33333333,1440'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Switzerland

text: Graubunden;Sent

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 349512

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: PI 349512

text: subsp. aestivum

characteristic: submission description

text: leaf

characteristic: tissue type


text: bread wheat

characteristic: common name

text: LUTESCENS ALEF 3254

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002700 - Accession Name = 'LUTESCENS ALEF 3254'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Russia

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

text: leaf

characteristic: variety


text: bread wheat

text: CHINOLI 70

text: AWCC

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-002237 - Accession Name = 'CHINOLI 70'; Remarks = 'Soft / Red'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Bolivia

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


characteristic: SRA accession

text: 1985 Federal District, Mexico by International Maize & Wheat Improvement Center. DONATED 12/01/1992 by Skovmand, B., International Maize & Wheat

characteristic: collected by

text: bread wheat

text: Opata 85

text: exome sequences of ExomeCapture-WSC-1-3 - Accession Name = 'Opata 85'; Remarks = '.'; Released = '1985'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Bluejay/Jupateco 73'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Mexico

text: CYMMIT

text: PI 591776

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 591776

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: leaf

text: :Opata 85;:Cheel;:BW 4113


text: Arusha, Tanzania by Director of Agriculture

text: bread wheat

text: B 192

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001205 - Accession Name = 'B 192'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '-3.36666667,36.68333333,1415'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Tanzania

text: Arusha;Arusha

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 203080

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 203080

text: subsp. aestivum

characteristic: submission description

characteristic: submission title

text: leaf

text: :B 192


text: bread wheat

characteristic: common name

text: PERSIA 20

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007691 - Accession Name = 'PERSIA 20'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Iran

characteristic: geographic location (country and/or sea)

text: SULTAN;KHOMEIN KAMUREH, SULTAN

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

text: leaf

characteristic: tissue type


text: Jordan by U.S. Operations Mission to Jordan

text: bread wheat

text: C.C.C.

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-003735 - Accession Name = 'C.C.C.'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Jordan

text: PI 223151

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 223151

text: subsp. aestivum

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf

text: :C.C.C.

characteristic: variety


characteristic: SRA accession

text: Luxembourg, Belgium by. DONATED 11/20/1997 by de Froidmont, D., Centre de Recherches Agronomiques

characteristic: collected by

text: dinkel wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004418 - Accession Name = 'GBXTS-0036'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '49.9,5.13333333,390'; Ancestry = '.'

text: 2 week old

text: winter wheat

characteristic: ecotype

text: Belgium

text: Luxembourg;Paliseul

text: PI 615267

text: Triticum spelta

characteristic: organism

text: Triticum aestivum subsp. spelta

text: USDA GRIN:PI 615267

characteristic: specimen voucher

text: subsp. spelta

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf

text: :GBXTS-0036;USA126:NSGC 7427;:207


text: Lebanon by. DONATED 1972 by Hafiz, A., UN-FAO

text: bread wheat

text: Khosti

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001551 - Accession Name = 'Khosti'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Lebanon

text: CItr 15397

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:CItr 15397

text: subsp. aestivum

characteristic: sub species

characteristic: submission description

text: leaf

text: :Khosti;:CI 15397


text: 1956 Iwate, Japan by. DONATED 10/31/1973 by Central Agricultural Experiment Station

text: bread wheat

characteristic: common name

text: Furutsu Masari

characteristic: cultivar

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-003731 - Accession Name = 'Furutsu Masari'; Remarks = '.'; Released = '1956'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Tohoku 78/Norin 39'

text: 2 week old

text: spring wheat

text: Japan

text: PI 383988

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 383988

text: subsp. aestivum

characteristic: submission title

text: leaf

text: :Furutsu Masari;:Norin 94;:Komugi Nourin 94;:Tohoku 105;:20052


text: bread wheat

text: DIOSEQ 3

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007099 - Accession Name = 'DIOSEQ 3'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: not provided

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

text: leaf

characteristic: tissue type


text: Lisboa, Portugal by Instituto Superior de Agronomia

text: bread wheat

text: CI 7040

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-003928 - Accession Name = 'CI 7040'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Anafil/Mocho de espiga branca'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Portugal

text: PI 56232

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 56232

text: subsp. aestivum

text: leaf

text: :CItr 7040;:CI 7040


characteristic: SRA accession

text: Portugal by Estacao de Melhoramento de Plantas. DONATED 12/29/1949 by Estacao Agronomica Nacional

text: bread wheat

text: Ideal

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001493 - Accession Name = 'Ideal'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Galego Barbado/Lobeiro'

text: 2 week old

text: spring wheat

text: Portugal

text: PI 185713

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 185713

text: subsp. aestivum

text: leaf

characteristic: variety


text: bread wheat

text: GREECE 28

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007093 - Accession Name = 'GREECE 28'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Greece

text: CORFU ISLAND;CORFU ISLAND

characteristic: geographic location (region and locality)

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: bread wheat

text: exome sequences of ExomeCapture-WSC-1-1 - Accession Name = 'RAC875'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: leaf


text: bread wheat

characteristic: common name

text: CHERNOUSKA DURUM

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002236 - Accession Name = 'CHERNOUSKA DURUM'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Russia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission description

text: leaf


text: Saudi Arabia by Guarino, L., International Plant Genetic Resources Institute

characteristic: collected by

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-003977 - Accession Name = '15067'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Saudi Arabia

characteristic: geographic location (country and/or sea)

text: PI 574350

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 574350

text: subsp. aestivum

characteristic: submission identifier

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

characteristic: submission title

text: leaf

text: :15067;:NSGC 1380


text: Oregon, United States by Kronstad, W., Oregon State University

text: bread wheat

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-004165 - Accession Name = '900192'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aurora/3/Minn/Heines Kolben/38 M.A./4/Yamhill/Era/5/85CB077'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: USA

text: PI 620691

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 620691

text: subsp. aestivum

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf

characteristic: tissue type

text: :900192;USA126:NSGC 8121


characteristic: SRA accession

text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000117 - Accession Name = 'Aus30271/annuello*5'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus30271/annuello'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Australia

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf

text: Aus30271 = GAE.SQUARROSA (163)

characteristic: variety


text: bread wheat

text: CHINA Sh59

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007260 - Accession Name = 'CHINA Sh59'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: China

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

characteristic: specimen voucher

text: subsp. aestivum

text: leaf


text: Lima, Peru by Programa Cooperativo de Experimentacion Agropecuaria

text: bread wheat

characteristic: common name

characteristic: cultivar

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-003903 - Accession Name = '1B-55'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Maribal/S.R.'

text: 2 week old

text: spring wheat

text: Peru

text: PI 232785

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 232785

text: subsp. aestivum

characteristic: sub species

text: leaf


text: Tajikistan by. DONATED 10/17/1991 by N.I. Vavilov Research Institute of Plant Industry

characteristic: collected by

text: bread wheat

text: Tadzykskaja 13

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004599 - Accession Name = 'Tadzykskaja 13'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Fortunato/Irody 1006'

text: 2 week old

text: winter wheat

text: Tajikistan

characteristic: geographic location (country and/or sea)

text: PI 565404

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 565404

text: subsp. aestivum

characteristic: submission description

text: leaf

text: :Tadzykskaja 13;:WIR 56161;:MAC9192-674


text: bread wheat

text: AVS

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-000462 - Accession Name = 'Aus34431/annuello*24'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus34431/annuello'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

characteristic: submission title

text: leaf

text: Aus34431 = 68.111/RGB-U//WARD/3/AE.SQUARROSA (329)


text: Idaho, United States by Chen, J., University of Idaho

text: bread wheat

text: UI Stone

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001495 - Accession Name = 'UI Stone'; Remarks = 'Soft white spring wheat. UI Stone exhibits improved grain yield, end-use quality (super soft), and resistance to cyst nematodes. It is adapted to rain-fed production systems in the intermountain zone of the western U.S.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Pomerelle*2/Tui'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: USA

text: PI 660550

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 660550

text: subsp. aestivum

text: leaf

characteristic: tissue type

text: :UI Stone;:IDO599;:A94368S-B-7;USA126:NSGC 19508


characteristic: SRA accession

text: bread wheat

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007285 - Accession Name = 'Aus27467'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Australia

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: bread wheat

text: VARNA 17

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007563 - Accession Name = 'VARNA 17'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Bulgaria

text: TORLAK;SVALENE VILLAGE, ROUSTCHOUK DISTRICT (TORLAK)

characteristic: geographic location (region and locality)

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

text: leaf

characteristic: variety


text: bread wheat

characteristic: common name

text: HATIF INVERSABLE

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002453 - Accession Name = 'HATIF INVERSABLE'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: France

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf


text: bread wheat

text: AVS

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-000166 - Accession Name = 'Aus30290/annuello*36'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus30290/annuello'

text: 2 week old

text: spring wheat

text: Australia

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

characteristic: submission description

text: leaf

text: Aus30290 = ALTAR 84/AE.SQUARROSA (502)


text: Romania by. DONATED 10/1987 by Moseman, J., USDA-ARS

characteristic: collected by

text: bread wheat

text: Transelvania 1

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004609 - Accession Name = 'Transelvania 1'; Remarks = 'Resistance to yellow (stripe) rust.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'US 60-43/Aurora//Fiorello/Bezostaia 1'

characteristic: description

text: 2 week old

text: winter wheat

text: Romania

text: PI 519267

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 519267

text: subsp. aestivum

characteristic: submission identifier

characteristic: submission title

text: leaf

text: :Transelvania 1;:Turda 141


characteristic: SRA accession

text: bread wheat

text: PERSIA 6

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007708 - Accession Name = 'PERSIA 6'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: spring wheat

characteristic: ecotype

text: Iran

text: Shahriar;Abbas Abad, Shahriar

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf

characteristic: tissue type


text: bread wheat

text: TUNIS 10

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007759 - Accession Name = 'TUNIS 10'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Tunisia

text: Beja;Oued Zargua, Beja

characteristic: geographic location (region and locality)

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

text: leaf


text: bread wheat

characteristic: common name

text: DACHNAYA 7

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002261 - Accession Name = 'DACHNAYA 7'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Ukraine

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

text: leaf

characteristic: variety


text: bread wheat

text: AVS

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-000767 - Accession Name = 'Aus30288/2*Annuello*7'; Remarks = 'BC2F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus30288/2*Annuello'

text: 2 week old

text: spring wheat

text: Australia

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: sub species

characteristic: submission description

text: leaf

text: Aus30288 = CROC_1/AE.SQUARROSA (466)


text: bread wheat

text: AMARELO DE BARBA BRANCA

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002049 - Accession Name = 'AMARELO DE BARBA BRANCA'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

characteristic: description

text: 2 week old

text: Portugal

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

characteristic: submission title

text: leaf


characteristic: SRA accession

text: bread wheat

text: TRIDENT

text: AWCC

text: exome sequences of ExomeCapture-DAS5-003131 - Accession Name = 'TRIDENT'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: spring wheat

characteristic: ecotype

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: Ethiopia by. DONATED by S.I.S. Societa Italiana Sementi S.P.A.. DONATED 09/28/1950 by Estacao de Melhoramento de Plantas

characteristic: collected by

text: bread wheat

text: Matte Lungo

text: exome sequences of ExomeCapture-WSC-7-6 - Accession Name = 'Matte Lungo'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Ethiopia

text: PI 192147

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 192147

text: subsp. aestivum

text: leaf

characteristic: tissue type

text: :Matte Lungo;:3566;:Tipo 63


text: 1912 Victoria, Australia by Pye, H., Dookie Agricultural College. DONATED 03/03/1936 by Pridham, J., Cowra Experiment Farm

text: bread wheat

characteristic: common name

text: Currawa

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-003329 - Accession Name = 'Currawa'; Remarks = '.'; Released = '1912'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Northern Champion/Cretan//Little Club '

text: 2 week old

text: spring wheat

text: Australia

text: PI 113916

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 113916

text: subsp. aestivum

text: leaf

text: :Currawa;:C 9220


text: PRE 1930 Syria by Watkins, A., University of Cambridge. DONATED 01/11/1962 by Dept. of Scientific & Industrial Res.

text: bread wheat

text: Aleppo 28

characteristic: cultivar

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004059 - Accession Name = 'Aleppo 28'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Syria

text: PI 278545

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 278545

characteristic: specimen voucher

text: subsp. aestivum

text: leaf

text: :Aleppo 28

characteristic: variety


text: Russian Federation by Vavilov, N., N.I. Vavilov Institute of Plant Industry

text: bread wheat

text: CI 7635

text: exome sequences of ExomeCapture-Cltr-7635 - Accession Name = 'CI 7635'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Russia

characteristic: geographic location (country and/or sea)

text: CItr 7635

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: CItr 7635

text: subsp. aestivum

characteristic: sub species

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf

text: :CI 7635


text: New South Wales, Australia by Wenholz, H., Department of Agriculture

text: bread wheat

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-003327 - Accession Name = 'C9458'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Federation/Webster'

characteristic: description

text: 2 week old

text: spring wheat

text: Australia

text: PI 117752

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 117752

text: subsp. aestivum

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

characteristic: submission description

text: leaf


characteristic: SRA accession

text: Idaho, United States by Souza, E., University of Idaho; Guttieri, M., University of Idaho

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001496 - Accession Name = 'IDO629'; Remarks = 'IDO629 is a soft white spring wheat adapted to irrigated production in southern Idaho. It is a waxy wheat, in that it has little or no amylose in its endosperm starch. IDO629 has weak gluten and moderate kernel size (30 to 35 mg). It is moderately resistant to stripe rust based on 2005 evaluations. The head is lax, white chaffed at maturity, and awned.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'IDO505*2/3/Kanto79/2*IDO488//BaiHuo,wxy'

text: 2 week old

text: spring wheat

text: USA

text: PI 642365

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 642365

text: subsp. aestivum

characteristic: submission identifier

characteristic: submission title

text: leaf

text: :IDO629;:A00149S-4;USA126:NSGC 9998


text: 11/06/1981 Darfur, Sudan by Croston, R., IBPGR; El Ahmadi, A., Plant Breeding Section

characteristic: collected by

text: bread wheat

text: exome sequences of ExomeCapture-WSC-4-5 - Accession Name = '123'; Remarks = 'Local original source. Sown August, harvested November.'; Released = '.'; Lattitude,Longitude,Elevation = '12.85,24.38333333,2100'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: spring wheat

characteristic: ecotype

text: Sudan

text: Darfur;1km west from junction to Gur Lambang, Jebel Marra

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 481923

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 481923

text: subsp. aestivum

text: leaf


text: Portugal by Loegering, W., USDA-ARS, Crops Research Division. DEVELOPED Portugal by

text: bread wheat

characteristic: common name

text: Barbaro 789

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-003925 - Accession Name = 'Barbaro 789'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Portugal

text: PI 269248

characteristic: material

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 269248

text: subsp. aestivum

text: leaf

characteristic: tissue type

text: :Barbaro 789;:I 845


text: bread wheat

text: Wyalkatchem

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-DAS5-WYALKATCHEM - Accession Name = 'Wyalkatchem'; Remarks = 'Hard / White'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Australia

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: leaf

characteristic: variety


characteristic: SRA accession

text: 1941 Finland by Central Experiment Station of Finland

text: bread wheat

text: Kimmo

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-001553 - Accession Name = 'Kimmo'; Remarks = '.'; Released = '1941'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'selection from Russian population'

characteristic: description

text: 2 week old

text: spring wheat

text: Finland

text: PI 181469

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 181469

text: subsp. aestivum

characteristic: submission description

characteristic: submission identifier

text: leaf

text: :Kimmo


text: bread wheat

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002342 - Accession Name = 'ERYT977.89'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: winter wheat

characteristic: ecotype

text: Ukraine

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission title

text: leaf


text: bread wheat

characteristic: common name

text: CHINA Sh6

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007261 - Accession Name = 'CHINA Sh6'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: China

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: Zimbabwe by. DONATED 09/1983 by Kilpatrick, R., Small Grain Centre

characteristic: collected by

text: bread wheat

text: Shashi

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001850 - Accession Name = 'Shashi'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'F1518 (Mexico)//Kafue/Mara 13D '

text: 2 week old

text: spring wheat

text: Zimbabwe

text: PI 479669

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 479669

text: subsp. aestivum

text: leaf

text: :Shashi;:S.A. 1345


text: bread wheat

text: RUMANIA 4

characteristic: cultivar

text: AWCC

text: exome sequences of ExomeCapture-WATKINS-007515 - Accession Name = 'RUMANIA 4'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Romania

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf

characteristic: tissue type


text: Washington, United States by Allan, R., USDA-ARS; Washington State University; Rubenthaler, G., USDA-ARS

text: bread wheat

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004299 - Accession Name = '68R2204'; Remarks = 'Restorer line for T. timopheevii cyto-male sterility. One gene semidwarf. Spikes lax, bearded, with white chaff. Seeds soft, white. Intermediate resistance to stripe rust.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'KS63GH279//3*CI 13438/Burt 8'

text: 2 week old

text: W-S

text: USA

text: PI 473550

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 473550

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf

characteristic: variety


characteristic: SRA accession

text: bread wheat

text: exome sequences of ExomeCapture-WSC-4-6 - Accession Name = '.'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '27.53333333,89.95,1600'; Ancestry = '.'

characteristic: description

text: 2 week old

text: spring wheat

text: Bhutan

text: Wangdue Phodrang;Semina, 15km from Wangdi District

characteristic: geographic location (region and locality)

characteristic: lat lon

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: leaf


text: bread wheat

text: exome sequences of ExomeCapture-WSC-7-4 - Accession Name = '.'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '35.166667,33.366667,.'; Ancestry = '.'

text: 2 week old

characteristic: dev stage

text: spring wheat

characteristic: ecotype

text: Cyprus

text: PI 210945

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 210945

text: subsp. aestivum

characteristic: submission description

characteristic: submission identifier

text: leaf


text: 11/1954 East Azerbaijan, Iran by Smith, E., USDA-ARS

characteristic: collected by

text: bread wheat

characteristic: common name

text: exome sequences of ExomeCapture-WSC-7-2 - Accession Name = '1660'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '38.08333333,46.3,1399'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Iran

text: East Azerbaijan;Dept. of Agriculture, Tabriz

text: PI 222669

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 222669

text: subsp. aestivum

characteristic: submission title

text: leaf


text: bread wheat

text: TRINTANI

characteristic: cultivar

text: AWCC

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-003134 - Accession Name = 'TRINTANI'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Brazil

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: subsp. aestivum

text: leaf


characteristic: SRA accession

text: 1933 Cape Province, South Africa by Winter Rainfall Region Station

text: bread wheat

text: Koalisie

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004657 - Accession Name = 'Koalisie'; Remarks = '.'; Released = '1933'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Kleintrou//Gluyas Early/Spring Early'

text: 2 week old

text: spring wheat

text: South Africa

text: PI 227197

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 227197

characteristic: specimen voucher

text: subsp. aestivum

characteristic: sub species

text: leaf

characteristic: tissue type

text: :Koalisie

characteristic: variety


text: Maryland, United States by Sammons, D., University of Maryland; Baenziger, P., USDA, ARS; Smith, D., USDA, ARS

text: bread wheat

text: Male Sterile Soft Red Winter

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001612 - Accession Name = 'Male Sterile Soft Red Winter'; Remarks = 'Soft red winter wheat segregating for a dominant male sterile gene (FS6). Segregates for a wide range of agronomic characteristics.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Cross between male sterile segregants having T. tauschii cytoplasm and soft red winter wheat cultivars.'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

characteristic: ecotype

text: USA

text: PI 552989

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 552989

text: subsp. aestivum

text: leaf

text: :Male Sterile Soft Red Winter


text: 1960 Kabul, Afghanistan by Harlan, J., USDA-ARS

characteristic: collected by

text: bread wheat

text: exome sequences of ExomeCapture-PI-268466 - Accession Name = '254'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '34.51666667,69.18333333,1784'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Afghanistan

text: Kabu;Agronomy plots, Kabul University

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 268466

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 268466

text: subsp. aestivum

characteristic: submission description

characteristic: submission identifier

text: leaf


text: bread wheat

characteristic: common name

text: RUMANIA 11

characteristic: cultivar

text: AWCC

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-002943 - Accession Name = 'RUMANIA 11'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Romania

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

characteristic: submission title

text: leaf


characteristic: SRA accession

text: 1955 South Island, New Zealand by Dept. of Scientific & Industrial Res.

text: bread wheat

text: Arawa

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001196 - Accession Name = 'Arawa'; Remarks = '.'; Released = '1955'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'India 9/2*Solid Straw Tuscan//Dreadnought/3/Cross 7//Federation/Kenya 744'

text: 2 week old

text: spring wheat

text: New Zealand

characteristic: geographic location (country and/or sea)

text: PI 283872

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

text: USDA GRIN:PI 283872

characteristic: specimen voucher

text: subsp. aestivum

text: leaf

text: :Arawa


text: 09/1981 by Australian Winter Cereals Collection. DEVELOPED 1981 Australia by Dekalb Shand Seed Company, Limited

text: bread wheat

text: Terra

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-001910 - Accession Name = 'Terra'; Remarks = 'Terra is the male parent of Hybrid Titan.'; Released = '1981'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Fertility Restorer/Gaines//Norin 53/3/Kite sib '

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Australia

text: PI 464646

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 464646

text: subsp. aestivum

characteristic: sub species

text: The exome sequenced hexaploid wheat accessions were selected from a worldwide population of landraces and cultivars obtained from the USDA National Small Grains Collection and the Australian Grains Genebank (formally the Australian Winter Cereal Collection). The worldwide population comprised 3990 accessions from 106 countries that were genotyped using the Infinium iSelect 90K SNP wheat bead chip array. The MCG method was used to select accessions for exome sequencing. This method uses a genetic relationship matrix calculated from genotype data to iteratively chose and arbitrary number of accessions (in the case of this study 20% of the accessions) that collectively explain the largest proportion of variance in genetic relationships among the whole set. Genomic DNA was extracted from leaf tissue for each accession using the Agencourt DNAdvance Genomic DNA Isolation Kit (Beckman Coulter) and subjected to sequence capture using the NimbleGen SeqCap EZ wheat whole genome assay. In brief, 1 µg of DNA was fragmented with the Covaris S2 instrument to obtain an average fragment length of 300 bp. Shorter fragments were removed using Agencourt AMPure XP beads (Beckman Coulter). The KAPA Library Preparation Kit (Kapa Biosystems) and adapters supplied in the NimbleGen SeqCap EZ Reagent Kit Plus v2 (Roche) were used to prepare sample libraries for the capture assay, according to the KAPA protocol but excluding steps 8.1-8.22. The quality and yield of each sample library was assessed using an Agilent 2200 TapeStation (Agilent Technologies) before proceeding to the sequence capture assay following the Roche protocol. Each target capture sequence enriched sample library was sequenced on an Illumina HiSeq2000 instrument (Illumina) to generate about 30 million reads per accession. The project leaders are Matthew Hayden (Agriculture Victoria, AgriBio, Centre for AgriBioscience, Bundoora, Victoria, Australia; La Trobe University, Bundoora, Victoria, Australia) and Eduard Akhunov (Kansas State University, USA). More information can be found on our project website at http://wheatgenomics.plantpath.ksu.edu/1000EC

text: leaf

characteristic: tissue type

text: :Terra;:AUS 20911

characteristic: variety


text: bread wheat

text: DIAMOND

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002283 - Accession Name = 'DIAMOND'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Finland

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission description

text: leaf


text: bread wheat

text: VALKI 141-R-E-34

text: AWCC

text: exome sequences of ExomeCapture-DAS5-003183 - Accession Name = 'VALKI 141-R-E-34'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: Russia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission identifier

text: leaf


text: Oregon, United States by Kronstad, W., Oregon State University

characteristic: collected by

text: bread wheat

characteristic: common name

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004161 - Accession Name = '3920068'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '14IBWSN19/3417.04'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: USA

text: PI 620689

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 620689

text: subsp. aestivum

text: leaf

text: :3920068;USA126:NSGC 8119


text: 1968 Cyprus by Bennett, E., Crop Ecology & Genetic Resources Unit

text: bread wheat

text: FAO 29.913

characteristic: cultivar

text: USDA GRIN

characteristic: culture collection

text: exome sequences of ExomeCapture-DAS5-003480 - Accession Name = 'FAO 29.913'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Separation of species from PI 372447'

text: 2 week old

text: spring wheat

text: Cyprus

text: PI 608795

characteristic: material

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 608795

text: subsp. aestivum

text: leaf

text: :FAO 29.913;USA126:NSGC 7606


characteristic: SRA accession

text: bread wheat

text: KLEIN PROTEO

text: AWCC

text: exome sequences of ExomeCapture-DAS5-002584 - Accession Name = 'KLEIN PROTEO'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

text: Argentina

characteristic: geographic location (country and/or sea)

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission title

text: leaf


text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000221 - Accession Name = 'Aus30301/annuello*10'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus30301/annuello'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

characteristic: organism

text: Triticum aestivum subsp. aestivum

characteristic: scientific name

characteristic: specimen voucher

text: subsp. aestivum

text: leaf

text: Aus30301 = CETA/AE.SQUARROSA (1027)


text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000358 - Accession Name = 'Aus34232/correll*63'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus34232/correll'

characteristic: description

text: 2 week old

characteristic: dev stage

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: sub species

text: leaf

text: Aus34232 = DOY1/AE.SQUARROSA (188)


text: bread wheat

text: AVS

text: exome sequences of ExomeCapture-DAS5-000118 - Accession Name = 'Aus30271/annuello*52'; Remarks = 'BC1F4 selection'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = 'Aus30271/annuello'

text: 2 week old

text: spring wheat

text: Australia

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: subsp. aestivum

characteristic: submission description

text: leaf

characteristic: tissue type

text: Aus30271 = GAE.SQUARROSA (163)

characteristic: variety


text: Azerbaijan by Central Transcaucasian Agric. Plant Breeding & Exp. Station

characteristic: collected by

text: bread wheat

characteristic: common name

text: Kirda Boogda

text: USDA GRIN

text: exome sequences of ExomeCapture-DAS5-004465 - Accession Name = 'Kirda Boogda'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '.,.,.'; Ancestry = '.'

text: 2 week old

text: winter wheat

text: Azerbaijan

text: PI 73361

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: USDA GRIN:PI 73361

text: subsp. aestivum

characteristic: submission identifier

text: leaf

text: :Kirda Boogda;:1644;:CItr 9231;:CI 9231


text: Varmland, Sweden by. DONATED 09/28/1950 by Estacao de Melhoramento de Plantas

text: bread wheat

text: Forma Vinda de Varmland

characteristic: cultivar

text: exome sequences of ExomeCapture-WSC-7-5 - Accession Name = 'Forma Vinda de Varmland'; Remarks = '.'; Released = '.'; Lattitude,Longitude,Elevation = '59.75,13.25,.'; Ancestry = '.'

text: 2 week old

text: spring wheat

characteristic: ecotype

text: Sweden

text: Varmland;Varmland

characteristic: geographic location (region and locality)

characteristic: lat lon

text: PI 192569

text: Triticum aestivum

text: Triticum aestivum subsp. aestivum

text: PI 192569

text: subsp. aestivum

text: Exome sequencing of diverse collection of wheat landraces, cultivars and breeding lines

text: leaf

text: :Forma Vinda de Varmland;:2139A


characteristic: SRA accession

text: wheat

text: Variants developed on the basis of 500 genotypes of winter wheat

text: Triticum aestivum

text: Triticum aestivum L.

text: The aim of the project is the search for sources of wheat resistance to Puccinia striiformis infection. SNP markers will be used in the project. A resistance-diversified wheat population was investigated. Wheat resistance to the fungus and other parameters, which are significant in the farming of the cultivar, ware determined in a field. The project included a characterization of the fungal population in terms of the occurrence of its races and biology. The goal of the project was an investigation of the wheat population in terms of its resistance to the fungus, finding the markers linkage to resistance, a characterization of the fungal population and the determination of some elements.

text: Searching for sources of wheat resistance to Puccinia striiformis (yellow rust) infection as an element of integrated plant protection.

characteristic: submission title

Name: Department of Biochemistry and Biotechnology

Address: ul. Dojazd 11, 60-632 Poznan, Poland

Lukasz Wolko

FirstName: Lukasz

LastName: Wolko


T. durum panel 1

text: T. durum1

text: Triticum turgidum subsp. durum

characteristic: organism

text: Triticum turgidum

characteristic: scientific name

text: Integration of different approaches for wheat adaptation to mediterranean agroenvironments

text: Novel tools to improve wheat adaptation in Andalusia

Genomics and Bioinformatics

Address: Alameda del Obispo, s/n, 14004, Cordoba, Spain

Pilar Hernandez

FirstName: Pilar

LastName: Hernandez


text: IR162_215_VCF_v1 - Imatinib_responder_162_leukaemia_CD34

characteristic: description

text: Homo sapiens

text: homo sapien

text: To investigate the potential of genetic variants in epigenetic modifiers as biomarkers at diagnosis of chronic myeloid leukaemia (CML), we used Ion Torrent next-generation sequencing of 71 candidate genes for predicting response to tyrosine kinase-inhibitors and probability of disease progression. 124 subjects with newly-diagnosed chronic-phase CML began with imatinib (n=62) or second-generation tyrosine kinase-inhibitors (n=62) and were classified as responders or non-responders based on the BCRABL1 transcript levels within the first year and the European LeukemiaNet criteria for failure. Somatic variants affecting 21 genes (e.g. ASXL1, IKZF1, DNMT3A, CREBBP) were detected in 30% of subjects, most of whom were non-responders (41% non-responders, 18% responders to imatinib, 38% non-responders, 25% responders to second-generation tyrosine kinase-inhibitors). The presence of variants predicted the rate of achieving a major molecular response, event-free survival, progression-free survival and chronic-myeloid-leukaemia-related survival in the imatinib but not the second-generation tyrosine kinase-inhibitors cohort. Rare germline variants had no prognostic significance irrespective of treatment while some pre-leukaemia variants suggest a multi-step development of chronic myeloid leukaemia. Our data suggest that identification of somatic variants at diagnosis facilitates stratification into imatinib responders/non responders, thereby allowing earlier use of second-generation tyrosine kinase-inhibitors, which, in turn, may overcome the negative impact of such variants on disease progression.

text: Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second generation tyrosine kinase inhibitors

CML laboratory Prof Jane F Apperley

Address: 4th floor Commonwealth Building, Hammersmith

Georgios Nteliopoulos

FirstName: Georgios

LastName: Nteliopoulos


text: 2GNR567_C_592T_VCF_v1 - 2G_TKI_non_responder_567_control_T_cells

text: Homo sapiens

text: homo sapien


text: INR15_3573_VCF_v1 - Imatinib_non_responder_15_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: 2GR211_259_VCF_v1 - 2G_TKI_responder_211_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: INR14_TL_4403_VCF_v1 - Imatinib_non_responder_14_leukaemia_Total_Leukocytes

text: Homo sapiens

text: homo sapien


text: IR5_4802_VCF_v1 - Imatinib_responder_5_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: 2GR269_C_313_R_VCF_v1 - 2G_TKI_responder_269_control_remission

text: Homo sapiens

text: homo sapien


text: INR10_C_4882_T_VCF_v1 - Imatinib_non_responder_10_control_T_cells

text: Homo sapiens

text: homo sapien


text: 2GR229_276_VCF_v1 - 2G_TKI_responder_229_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: 2GR189_C_240_R_VCF_v2 - 2G_TKI_responder_189_control_remission

text: Homo sapiens

text: homo sapien


text: IR25_C_5042_CMR_VCF_v1 - Imatinib_responder_25_control_remission

text: Homo sapiens

text: homo sapien


text: INR2_D14I_5623_14I_VCF_v1 - Imatinib_non_responder_2_leukaemia_InVitro_Day14_cytokines_imatinib

text: Homo sapiens

text: homo sapien


text: IRRP_C_26.09_R_VCF_v2 - Imatinib_responder_RP_control_remission

text: Homo sapiens

text: homo sapien


text: 2GR613_C_642R_VCF_v1 - 2G_TKI_responder_613_control_remission

text: Homo sapiens

text: homo sapien


text: INR17_TL_3955_MNC_124_VCF_v1 - Imatinib_non_responder_17_leukaemia_Total_Leukocytes

text: Homo sapiens

text: homo sapien


text: 2GNR247_290_VCF_v1 - 2G_TKI_non_responder_247_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: IR4_C_5300_WB_CMR_VCF_v1 - Imatinib_responder_4_control_remission

text: Homo sapiens

text: homo sapien

text: To investigate the potential of genetic variants in epigenetic modifiers as biomarkers at diagnosis of chronic myeloid leukaemia (CML), we used Ion Torrent next-generation sequencing of 71 candidate genes for predicting response to tyrosine kinase-inhibitors and probability of disease progression. 124 subjects with newly-diagnosed chronic-phase CML began with imatinib (n=62) or second-generation tyrosine kinase-inhibitors (n=62) and were classified as responders or non-responders based on the BCRABL1 transcript levels within the first year and the European LeukemiaNet criteria for failure. Somatic variants affecting 21 genes (e.g. ASXL1, IKZF1, DNMT3A, CREBBP) were detected in 30% of subjects, most of whom were non-responders (41% non-responders, 18% responders to imatinib, 38% non-responders, 25% responders to second-generation tyrosine kinase-inhibitors). The presence of variants predicted the rate of achieving a major molecular response, event-free survival, progression-free survival and chronic-myeloid-leukaemia-related survival in the imatinib but not the second-generation tyrosine kinase-inhibitors cohort. Rare germline variants had no prognostic significance irrespective of treatment while some pre-leukaemia variants suggest a multi-step development of chronic myeloid leukaemia. Our data suggest that identification of somatic variants at diagnosis facilitates stratification into imatinib responders/non responders, thereby allowing earlier use of second-generation tyrosine kinase-inhibitors, which, in turn, may overcome the negative impact of such variants on disease progression.


text: 2GNRES_43.14_VCF_v1 - 2G_TKI_non_responder_ES_leukaemia_CD34

text: Homo sapiens

text: homo sapien

text: Somatic variants in epigenetic modifiers can predict failure of response to imatinib but not to second generation tyrosine kinase inhibitors


text: INR17_BC_3955_VCF_v1 - Imatinib_non_responder_17_leukaemia_Blast_Crisis_Total_Leukocytes

text: Homo sapiens

text: homo sapien


text: INR267_312_VCF_v1 - Imatinib_non_responder_267_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: 2GR255_301_VCF_v1 - 2G_TKI_responder_255_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: 2GR321_365_VCF_v1 - 2G_TKI_responder_321_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: IR29_C_5057_CMR_VCF_v1 - Imatinib_responder_29_control_remission

text: Homo sapiens

text: homo sapien


text: IR4_MR3_5886_VCF_v1 - Imatinib_responder_4_MR3_CD34

text: Homo sapiens

text: homo sapien


text: INR9_5337_VCF_v1 - Imatinib_non_responder_9_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: INR10_2_4882_CD34_VCF_v1 - Imatinib_non_responder_10_r2_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: INR2_D14D_5623_14D_VCF_v1 - Imatinib_non_responder_2_leukaemia_InVitro_Day14_cytokines_dasatinib

text: Homo sapiens

text: homo sapien


text: IR6_C_5060_CMR_VCF_v1 - Imatinib_responder_6_control_remission

text: Homo sapiens

text: homo sapien


text: 2GRCOC_C_4.15_T_VCF_v1 - 2G_TKI_responder_COC_control_T_cells

text: Homo sapiens

text: homo sapien


text: 2GNR274_319_746_VCF_v2 - 2G_TKI_non_responder_274_leukaemia_CD34

text: Homo sapiens

text: homo sapien


text: IR20_C_3852_CMR_VCF_v1 - Imatinib_responder_20_control_remission

text: Homo sapiens

text: homo sapien


text: IR30_5454_VCF_v1 - Imatinib_responder_30_leukaemia_CD34

text: Homo sapiens

text: homo sapien