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text: d2c3317c-8c34-411b-a5ac-2b8fddddc5f1-dtol-specimen


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: UPSC

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: thale cress

characteristic: common name

text: 6-day old Arabidopsis cell cultures before treatment used as control - biological replicate 1

characteristic: description

text: Arabidopsis thaliana

characteristic: organism

text: Arabidopsis thaliana


text: UPSC

text: public

text: thale cress

text: 6-day old Arabidopsis cell cultures before treatment used as control - biological replicate 2

text: Arabidopsis thaliana

text: Arabidopsis thaliana

characteristic: title


text: UPSC

text: public

text: thale cress

text: 6-day old Arabidopsis cell cultures before treatment used as control - biological replicate 3

text: Arabidopsis thaliana

text: Arabidopsis thaliana


text: UPSC

text: public

text: thale cress

text: T0 cells treat with full medium (1x MS + 3% sucrose) + DMSO for 3 hours - Biological Replicate 1

text: Arabidopsis thaliana

text: Arabidopsis thaliana


text: UPSC

text: public

text: thale cress

text: T0 cells treat with full medium (1x MS + 3% sucrose) + DMSO for 3 hours - Biological Replicate 2

text: Arabidopsis thaliana

text: Arabidopsis thaliana


text: UPSC

text: public

text: thale cress

text: T0 cells treat with full medium (1x MS + 3% sucrose) + DMSO for 3 hours - Biological Replicate 3

text: Arabidopsis thaliana

text: Arabidopsis thaliana


E-MTAB-10302:DMSO rep1

text: The University of Manchester

text: public

text: E-MTAB-10302:DMSO rep1

tag: Namespace:The University of Manchester

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: Protocols: OE19 cells were treated with DMSO for 1 day or 500 nM lapatinib for 1, 7 or 35 days and then trypsinised and collected Omni ATAC-seq protocol: Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396 Omni ATAC-seq protocol: Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: DMSO rep1


E-MTAB-10302:DMSO rep2

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10302:DMSO rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: DMSO rep2


E-MTAB-10302:lapatinib day 1 rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10302:lapatinib day 1 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 1 rep1


E-MTAB-10302:lapatinib day 1 rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10302:lapatinib day 1 rep2

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 1 rep2


E-MTAB-10302:lapatinib day 35 rep1

text: The University of Manchester

text: public

text: E-MTAB-10302:lapatinib day 35 rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 35 rep1

characteristic: title


E-MTAB-10302:lapatinib day 35 rep2

text: The University of Manchester

text: public

text: E-MTAB-10302:lapatinib day 35 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: lapatinib day 35 rep2


E-MTAB-10302:lapatinib day 7 rep1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10302:lapatinib day 7 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 7 rep1


E-MTAB-10302:lapatinib day 7 rep2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10302:lapatinib day 7 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 7 rep2


E-MTAB-10304:DMSO rep1

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10304:DMSO rep1

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

text: Protocols: OE19 cells were treated with DMSO for 1 day or 500 nM lapatinib for 1, 7 or 35 days RNA was extracted using the RNeasy Plus Kit (Qiagen) RNA-seq libraries were constructed using Illumina TruSeq Stranded mRNA kit

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: DMSO rep1


E-MTAB-10304:DMSO rep2

text: The University of Manchester

text: public

text: E-MTAB-10304:DMSO rep2

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: DMSO rep2

characteristic: title


E-MTAB-10304:DMSO rep3

text: The University of Manchester

text: public

text: E-MTAB-10304:DMSO rep3

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: DMSO rep3


E-MTAB-10304:lapatinib day 1 rep1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10304:lapatinib day 1 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 1 rep1


E-MTAB-10304:lapatinib day 1 rep2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10304:lapatinib day 1 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 1 rep2


E-MTAB-10304:lapatinib day 1 rep3

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10304:lapatinib day 1 rep3

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 1 rep3


E-MTAB-10304:lapatinib day 35 rep1

text: The University of Manchester

text: public

text: E-MTAB-10304:lapatinib day 35 rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 35 rep1

characteristic: title


E-MTAB-10304:lapatinib day 35 rep2

text: The University of Manchester

text: public

text: E-MTAB-10304:lapatinib day 35 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: lapatinib day 35 rep2


E-MTAB-10304:lapatinib day 35 rep3

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10304:lapatinib day 35 rep3

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 35 rep3


E-MTAB-10304:lapatinib day 7 rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10304:lapatinib day 7 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 7 rep1


E-MTAB-10304:lapatinib day 7 rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10304:lapatinib day 7 rep2

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 7 rep2


E-MTAB-10304:lapatinib day 7 rep3

text: The University of Manchester

text: public

text: E-MTAB-10304:lapatinib day 7 rep3

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: lapatinib day 7 rep3

characteristic: title


E-MTAB-10307:DMSO rep1

text: The University of Manchester

text: public

text: E-MTAB-10307:DMSO rep1

text: ArrayExpress

text: human

text: Protocols: ESO26 cells were treated with DMSO or 500 nanomolar lapatinib for 24 hours and then collected by trypsinisation Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396 Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396

text: adult

text: adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagus

characteristic: organism part

text: Homo sapiens

text: DMSO rep1


E-MTAB-10307:DMSO rep2

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10307:DMSO rep2

text: ArrayExpress

text: human

text: adult

text: adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: DMSO rep2


E-MTAB-10307:lapatinib + AKTi rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10307:lapatinib + AKTi rep1

text: ArrayExpress

text: human

text: adult

text: adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: lapatinib + AKTi rep1


E-MTAB-10307:lapatinib + AKTi rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10307:lapatinib + AKTi rep2

characteristic: Submitter Id

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: adult

text: adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: lapatinib + AKTi rep2


E-MTAB-10306:DMSO rep1

text: The University of Manchester

text: public

text: E-MTAB-10306:DMSO rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: Protocols: WTSI-OESO_009 cells were treated with DMSO or 1 uM lapatinib for 24 hours Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396 Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: DMSO rep1

characteristic: title


E-MTAB-10306:DMSO rep2

text: The University of Manchester

text: public

text: E-MTAB-10306:DMSO rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagus

characteristic: organism part

text: Homo sapiens

text: DMSO rep2


E-MTAB-10306:lapatinib rep 1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10306:lapatinib rep 1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: lapatinib rep 1


E-MTAB-10306:lapatinib rep 2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10306:lapatinib rep 2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: lapatinib rep 2


E-MTAB-10310:DMSO rep1

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10310:DMSO rep1

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

text: Protocols: KYAE1 cells were treated with DMSO or 500 nM lapatinib for 24 hours and then collected by trypsinisation Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396 Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: DMSO rep1


E-MTAB-10310:DMSO rep2

text: The University of Manchester

text: public

text: E-MTAB-10310:DMSO rep2

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: DMSO rep2

characteristic: title


E-MTAB-10310:lapatinib rep1

text: The University of Manchester

text: public

text: E-MTAB-10310:lapatinib rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagus

characteristic: organism part

text: Homo sapiens

text: lapatinib rep1


E-MTAB-10310:lapatinib rep2

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10310:lapatinib rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagus

text: Homo sapiens

text: lapatinib rep2


E-MTAB-10313:NCI-N87 DMSO rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10313:NCI-N87 DMSO rep1

text: ArrayExpress

text: epithelial cell

text: human

text: Protocols: NCI-N87 cells were treated with DMSO control or 250 nM lapatinib for 24 hours and then collected by trypsinisation Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396 Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396

text: adult

text: gastric adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: stomach

text: Homo sapiens

text: NCI-N87 DMSO rep1


E-MTAB-10313:NCI-N87 DMSO rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10313:NCI-N87 DMSO rep2

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: gastric adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: stomach

text: Homo sapiens

text: NCI-N87 DMSO rep2


E-MTAB-10313:NCI-N87 lapatinib rep1

text: The University of Manchester

text: public

text: E-MTAB-10313:NCI-N87 lapatinib rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: gastric adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: stomach

text: Homo sapiens

text: NCI-N87 lapatinib rep1

characteristic: title


E-MTAB-10313:NCI-N87 lapatinib rep2

text: The University of Manchester

text: public

text: E-MTAB-10313:NCI-N87 lapatinib rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: gastric adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: stomach

characteristic: organism part

text: Homo sapiens

text: NCI-N87 lapatinib rep2


E-MTAB-10314:DMSO day 1 rep1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10314:DMSO day 1 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: Protocols: OE19 cells were treated with DMSO for 1 day or 500 nM lapatinib for 35 days or 500 nM lapatinib followed by lapatinib withdrawal for 1, 2, 3 or 14 days. Cells were collected by trypsinisation. Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396 Omni ATAC-seq protocol:Corces, M., Trevino, A., Hamilton, E. et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods 14, 959–962 (2017). https://doi.org/10.1038/nmeth.4396

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: DMSO day 1 rep1


E-MTAB-10314:DMSO day 1 rep2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10314:DMSO day 1 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: DMSO day 1 rep2


E-MTAB-10314:Resistant rep1

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10314:Resistant rep1

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Resistant rep1


E-MTAB-10314:Resistant rep2

text: The University of Manchester

text: public

text: E-MTAB-10314:Resistant rep2

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Resistant rep2

characteristic: title


E-MTAB-10314:Withdrawal day 1 rep1

text: The University of Manchester

text: public

text: E-MTAB-10314:Withdrawal day 1 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: Withdrawal day 1 rep1


E-MTAB-10314:Withdrawal day 1 rep2

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10314:Withdrawal day 1 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Withdrawal day 1 rep2


E-MTAB-10314:Withdrawal day 14 rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10314:Withdrawal day 14 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Withdrawal day 14 rep1


E-MTAB-10314:Withdrawal day 14 rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10314:Withdrawal day 14 rep2

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Withdrawal day 14 rep2


E-MTAB-10314:Withdrawal day 2 rep1

text: The University of Manchester

text: public

text: E-MTAB-10314:Withdrawal day 2 rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Withdrawal day 2 rep1

characteristic: title


E-MTAB-10314:Withdrawal day 2 rep2

text: The University of Manchester

text: public

text: E-MTAB-10314:Withdrawal day 2 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: Withdrawal day 2 rep2


E-MTAB-10314:Withdrawal day 3 rep1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10314:Withdrawal day 3 rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Withdrawal day 3 rep1


E-MTAB-10314:Withdrawal day 3 rep2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10314:Withdrawal day 3 rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: Withdrawal day 3 rep2


E-MTAB-10317:siNT DMSO rep1

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10317:siNT DMSO rep1

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

text: Protocols: OE19 cells were reverse transfected with siRNAs and then 24 hours post-transfection, cells were treated with DMSO or 500 nM lapatinib for 24 hours RNA was extracted using the RNeasy Plus Kit (Qiagen) RNA-seq libraries were constructed using Illumina TruSeq Stranded mRNA kit

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siNT DMSO rep1


E-MTAB-10317:siNT DMSO rep2

text: The University of Manchester

text: public

text: E-MTAB-10317:siNT DMSO rep2

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siNT DMSO rep2

characteristic: title


E-MTAB-10317:siNT DMSO rep3

text: The University of Manchester

text: public

text: E-MTAB-10317:siNT DMSO rep3

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: siNT DMSO rep3


E-MTAB-10317:siNT lapatinib rep1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10317:siNT lapatinib rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siNT lapatinib rep1


E-MTAB-10317:siNT lapatinib rep2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10317:siNT lapatinib rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siNT lapatinib rep2


E-MTAB-10317:siNT lapatinib rep3

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10317:siNT lapatinib rep3

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siNT lapatinib rep3


E-MTAB-10317:siPPARGC1A DMSO rep1

text: The University of Manchester

text: public

text: E-MTAB-10317:siPPARGC1A DMSO rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siPPARGC1A DMSO rep1

characteristic: title


E-MTAB-10317:siPPARGC1A DMSO rep2

text: The University of Manchester

text: public

text: E-MTAB-10317:siPPARGC1A DMSO rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: siPPARGC1A DMSO rep2


E-MTAB-10317:siPPARGC1A DMSO rep3

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10317:siPPARGC1A DMSO rep3

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siPPARGC1A DMSO rep3


E-MTAB-10317:siPPARGC1A lapatinib rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10317:siPPARGC1A lapatinib rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siPPARGC1A lapatinib rep1


E-MTAB-10317:siPPARGC1A lapatinib rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10317:siPPARGC1A lapatinib rep2

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siPPARGC1A lapatinib rep2


E-MTAB-10317:siPPARGC1A lapatinib rep3

text: The University of Manchester

text: public

text: E-MTAB-10317:siPPARGC1A lapatinib rep3

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: siPPARGC1A lapatinib rep3

characteristic: title


E-MTAB-10319:H3K27ac DMSO rep1

text: The University of Manchester

text: public

text: E-MTAB-10319:H3K27ac DMSO rep1

text: ArrayExpress

text: epithelial cell

text: human

text: Protocols: Cells were treated with DMSO or 500 nM lapatinib for 48 hours. Cells were then fixed with 1% formaldehyde ChIP was performed as described previously: eLife 2020;9:e57189 DOI: 10.7554/eLife.57189 ChIP-seq DNA library was prepared using Illumina TruSeq ChIP Library Prep Kit

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: H3K27ac DMSO rep1


E-MTAB-10319:H3K27ac DMSO rep2

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10319:H3K27ac DMSO rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: H3K27ac DMSO rep2


E-MTAB-10319:H3K27ac lapatinib rep1

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10319:H3K27ac lapatinib rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: H3K27ac lapatinib rep1


E-MTAB-10319:H3K27ac lapatinib rep2

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10319:H3K27ac lapatinib rep2

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: H3K27ac lapatinib rep2


E-MTAB-10319:HNF4A DMSO rep1

text: The University of Manchester

text: public

text: E-MTAB-10319:HNF4A DMSO rep1

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: HNF4A DMSO rep1

characteristic: title


E-MTAB-10319:HNF4A DMSO rep2

text: The University of Manchester

text: public

text: E-MTAB-10319:HNF4A DMSO rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: HNF4A DMSO rep2


E-MTAB-10319:HNF4A lapatinib rep1

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10319:HNF4A lapatinib rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: HNF4A lapatinib rep1


E-MTAB-10319:HNF4A lapatinib rep2

text: The University of Manchester

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-10319:HNF4A lapatinib rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: HNF4A lapatinib rep2


E-MTAB-10319:input DMSO

text: The University of Manchester

text: public

characteristic: SRA accession

text: E-MTAB-10319:input DMSO

characteristic: Submitter Id

text: ArrayExpress

text: epithelial cell

text: human

characteristic: common name

characteristic: description

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: input DMSO


E-MTAB-10319:input lapatinib

text: The University of Manchester

text: public

text: E-MTAB-10319:input lapatinib

text: ArrayExpress

characteristic: broker name

text: epithelial cell

text: human

text: adult

characteristic: developmental stage

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: input lapatinib

characteristic: title


E-MTAB-10319:PPARGC1A rep1

text: The University of Manchester

text: public

text: E-MTAB-10319:PPARGC1A rep1

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

characteristic: disease

text: wild type genotype

characteristic: genotype

text: not applicable

characteristic: isolate

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

characteristic: organism part

text: Homo sapiens

text: PPARGC1A rep1


E-MTAB-10319:PPARGC1A rep2

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: The University of Manchester

text: public

text: E-MTAB-10319:PPARGC1A rep2

text: ArrayExpress

text: epithelial cell

text: human

text: adult

text: esophageal adenocarcinoma

text: wild type genotype

text: not applicable

text: Homo sapiens

text: Homo sapiens

text: esophagogastric junction

text: Homo sapiens

text: PPARGC1A rep2


characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

tag: Namespace:Key Laboratory of Environmental and Applied Microbiology, CAS

characteristic: collection date

text: water

characteristic: environment (biome)

text: water

characteristic: environment (feature)

text: water

characteristic: environment (material)

text: China

characteristic: geographic location (country and/or sea)

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: host-associated

characteristic: host-associated environmental package

text: mimarks-survey

characteristic: investigation type

text: gut metagenome

characteristic: project name

text: gut metagenome

text: MiSeq

characteristic: sequencing method

text: water


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: Key Laboratory of Environmental and Applied Microbiology, CAS

text: public

characteristic: SRA accession

characteristic: Submitter Id

text: water

text: water

text: water

text: China

text: host-associated

text: mimarks-survey

text: gut metagenome

characteristic: organism

text: gut metagenome

text: MiSeq

text: water

characteristic: title


characteristic: External Id

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: collection date

text: human

characteristic: environment (biome)

text: human

text: human

text: China

text: host-associated

text: mimarks-survey

text: gut metagenome

text: gut metagenome

text: MiSeq

text: human