E-MTAB-11671_2:Sample 364

text: public

text: E-MTAB-11671_2:Sample 364

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 364

characteristic: title


E-MTAB-11671_2:Sample 365

status: PUBLIC

tag: attribute

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 365

tag: Namespace:Department of Infectious Disease Imperial College London

characteristic: Submitter Id

unit: month

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

characteristic: common name

text: Protocols: Whole blood was collected at the time of recruitment in PAXgene tubes RNA samples were stored at −80 °C until further analysis. After additional DNAse treatment, library preparation at paired end reads was conducted using the Illumina's TruSeq® RNA Sample Preparation Kit; ribosomal and globin RNA depletion

characteristic: description

text: infant

characteristic: developmental stage

text: Respiratory Syncytial Virus Infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 365


E-MTAB-11671_2:Sample 366

text: Department of Infectious Disease Imperial College London

text: public

text: E-MTAB-11671_2:Sample 366

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: male

characteristic: sex

text: Sample 366

characteristic: title


E-MTAB-11671_2:Sample 367

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 367

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 367


E-MTAB-11671_2:Sample 368

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 368

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 368


E-MTAB-11671_2:Sample 369

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 369

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: infant

text: Respiratory Syncytial Virus Infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 369


E-MTAB-11671_2:Sample 37

text: public

text: E-MTAB-11671_2:Sample 37

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: group A streptococcal infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 37


E-MTAB-11671_2:Sample 370

text: public

text: E-MTAB-11671_2:Sample 370

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: male

characteristic: sex

text: Sample 370

characteristic: title


E-MTAB-11671_2:Sample 371

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 371

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 371


E-MTAB-11671_2:Sample 372

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 372

text: ArrayExpress

text: human

text: infant

text: Respiratory Syncytial Virus Infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 372


E-MTAB-11671_2:Sample 373

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 373

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: femaleY

text: Sample 373


E-MTAB-11671_2:Sample 374

text: public

text: E-MTAB-11671_2:Sample 374

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Staphylococcus aureus infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 374


E-MTAB-11671_2:Sample 375

text: public

text: E-MTAB-11671_2:Sample 375

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: male

characteristic: sex

text: Sample 375

characteristic: title


E-MTAB-11671_2:Sample 376

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 376

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 376


E-MTAB-11671_2:Sample 377

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 377

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 377


E-MTAB-11671_2:Sample 378

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 378

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 378


E-MTAB-11671_2:Sample 379

text: public

text: E-MTAB-11671_2:Sample 379

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Staphylococcus aureus infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 379


E-MTAB-11671_2:Sample 38

text: public

text: E-MTAB-11671_2:Sample 38

text: ArrayExpress

text: human

text: juvenile stage

text: group A streptococcal infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 38

characteristic: title


E-MTAB-11671_2:Sample 380

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 380

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 380


E-MTAB-11671_2:Sample 381

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 381

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 381


E-MTAB-11671_2:Sample 382

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 382

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 382


E-MTAB-11671_2:Sample 383

text: public

text: E-MTAB-11671_2:Sample 383

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Staphylococcus aureus infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 383


E-MTAB-11671_2:Sample 384

text: public

text: E-MTAB-11671_2:Sample 384

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 384

characteristic: title


E-MTAB-11671_2:Sample 385

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 385

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 385


E-MTAB-11671_2:Sample 386

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 386

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 386


E-MTAB-11671_2:Sample 387

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 387

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 387


E-MTAB-11671_2:Sample 388

text: public

text: E-MTAB-11671_2:Sample 388

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: infant

characteristic: developmental stage

text: Staphylococcus aureus infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 388


E-MTAB-11671_2:Sample 389

text: public

text: E-MTAB-11671_2:Sample 389

text: ArrayExpress

text: human

text: infant

text: Staphylococcus aureus infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 389

characteristic: title


E-MTAB-11671_2:Sample 39

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 39

text: ArrayExpress

text: human

text: juvenile stage

text: group A streptococcal infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 39


E-MTAB-11671_2:Sample 390

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 390

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 390


E-MTAB-11671_2:Sample 391

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 391

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Staphylococcus aureus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 391


E-MTAB-11671_2:Sample 392

text: public

text: E-MTAB-11671_2:Sample 392

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Staphylococcus aureus infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 392


E-MTAB-11671_2:Sample 393

text: public

text: E-MTAB-11671_2:Sample 393

text: ArrayExpress

text: human

text: juvenile stage

text: Staphylococcus aureus infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: male

characteristic: sex

text: Sample 393

characteristic: title


E-MTAB-11671_2:Sample 394

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 394

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 394


E-MTAB-11671_2:Sample 395

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 395

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 395


E-MTAB-11671_2:Sample 396

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 396

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: infant

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 396


E-MTAB-11671_2:Sample 397

text: public

text: E-MTAB-11671_2:Sample 397

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Tuberculosis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 397


E-MTAB-11671_2:Sample 398

text: public

text: E-MTAB-11671_2:Sample 398

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 398

characteristic: title


E-MTAB-11671_2:Sample 399

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 399

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 399


E-MTAB-11671_2:Sample 4

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 4

text: ArrayExpress

text: human

text: juvenile stage

text: adenovirus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 4


E-MTAB-11671_2:Sample 40

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 40

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: infant

text: group A streptococcal infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 40


E-MTAB-11671_2:Sample 400

text: public

text: E-MTAB-11671_2:Sample 400

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Tuberculosis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 400


E-MTAB-11671_2:Sample 401

text: public

text: E-MTAB-11671_2:Sample 401

text: ArrayExpress

text: human

text: infant

text: Tuberculosis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: male

characteristic: sex

text: Sample 401

characteristic: title


E-MTAB-11671_2:Sample 402

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 402

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 402


E-MTAB-11671_2:Sample 403

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 403

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 403


E-MTAB-11671_2:Sample 404

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 404

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 404


E-MTAB-11671_2:Sample 405

text: public

text: E-MTAB-11671_2:Sample 405

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: Tuberculosis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 405


E-MTAB-11671_2:Sample 406

text: public

text: E-MTAB-11671_2:Sample 406

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 406

characteristic: title


E-MTAB-11671_2:Sample 407

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 407

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 407


E-MTAB-11671_2:Sample 408

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 408

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 408


E-MTAB-11671_2:Sample 409

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 409

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 409


E-MTAB-11671_2:Sample 41

text: public

text: E-MTAB-11671_2:Sample 41

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: infant

characteristic: developmental stage

text: group A streptococcal infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 41


E-MTAB-11671_2:Sample 410

text: public

text: E-MTAB-11671_2:Sample 410

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 410

characteristic: title


E-MTAB-11671_2:Sample 411

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 411

text: ArrayExpress

text: human

text: juvenile stage

text: Tuberculosis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 411


E-MTAB-11671_2:Sample 42

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 42

text: ArrayExpress

text: human

text: infant

text: group A streptococcal infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 42


E-MTAB-11671_2:Sample 43

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 43

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: group A streptococcal infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 43


E-MTAB-11671_2:Sample 44

text: public

text: E-MTAB-11671_2:Sample 44

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: infant

characteristic: developmental stage

text: influenza

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 44


E-MTAB-11671_2:Sample 45

text: public

text: E-MTAB-11671_2:Sample 45

text: ArrayExpress

text: human

text: juvenile stage

text: influenza

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 45

characteristic: title


E-MTAB-11671_2:Sample 46

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 46

text: ArrayExpress

text: human

text: infant

text: influenza

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 46


E-MTAB-11671_2:Sample 47

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 47

text: ArrayExpress

text: human

text: infant

text: influenza

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 47


E-MTAB-11671_2:Sample 48

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 48

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: infant

text: influenza

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 48


E-MTAB-11671_2:Sample 49

text: public

text: E-MTAB-11671_2:Sample 49

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: influenza

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 49


E-MTAB-11671_2:Sample 5

text: public

text: E-MTAB-11671_2:Sample 5

text: ArrayExpress

text: human

text: juvenile stage

text: adenovirus infection

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 5

characteristic: title


E-MTAB-11671_2:Sample 50

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 50

text: ArrayExpress

text: human

text: juvenile stage

text: influenza

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 50


E-MTAB-11671_2:Sample 51

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 51

text: ArrayExpress

text: human

text: infant

text: influenza

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 51


E-MTAB-11671_2:Sample 52

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 52

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 52


E-MTAB-11671_2:Sample 53

text: public

text: E-MTAB-11671_2:Sample 53

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 53


E-MTAB-11671_2:Sample 54

text: public

text: E-MTAB-11671_2:Sample 54

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 54

characteristic: title


E-MTAB-11671_2:Sample 55

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 55

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 55


E-MTAB-11671_2:Sample 56

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 56

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 56


E-MTAB-11671_2:Sample 57

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 57

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 57


E-MTAB-11671_2:Sample 58

text: public

text: E-MTAB-11671_2:Sample 58

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 58


E-MTAB-11671_2:Sample 59

text: public

text: E-MTAB-11671_2:Sample 59

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 59

characteristic: title


E-MTAB-11671_2:Sample 6

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 6

text: ArrayExpress

text: human

text: juvenile stage

text: adenovirus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 6


E-MTAB-11671_2:Sample 60

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 60

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 60


E-MTAB-11671_2:Sample 61

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 61

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 61


E-MTAB-11671_2:Sample 62

text: public

text: E-MTAB-11671_2:Sample 62

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 62


E-MTAB-11671_2:Sample 63

text: public

text: E-MTAB-11671_2:Sample 63

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 63

characteristic: title


E-MTAB-11671_2:Sample 64

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 64

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 64


E-MTAB-11671_2:Sample 65

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 65

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 65


E-MTAB-11671_2:Sample 66

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 66

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 66


E-MTAB-11671_2:Sample 67

text: public

text: E-MTAB-11671_2:Sample 67

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 67


E-MTAB-11671_2:Sample 68

text: public

text: E-MTAB-11671_2:Sample 68

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 68

characteristic: title


E-MTAB-11671_2:Sample 69

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 69

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 69


E-MTAB-11671_2:Sample 7

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 7

text: ArrayExpress

text: human

text: juvenile stage

text: adenovirus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 7


E-MTAB-11671_2:Sample 70

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 70

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 70


E-MTAB-11671_2:Sample 71

text: public

text: E-MTAB-11671_2:Sample 71

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 71


E-MTAB-11671_2:Sample 72

text: public

text: E-MTAB-11671_2:Sample 72

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 72

characteristic: title


E-MTAB-11671_2:Sample 73

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 73

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 73


E-MTAB-11671_2:Sample 74

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 74

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 74


E-MTAB-11671_2:Sample 75

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 75

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 75


E-MTAB-11671_2:Sample 76

text: public

text: E-MTAB-11671_2:Sample 76

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 76


E-MTAB-11671_2:Sample 77

text: public

text: E-MTAB-11671_2:Sample 77

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 77

characteristic: title


E-MTAB-11671_2:Sample 78

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 78

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 78


E-MTAB-11671_2:Sample 79

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 79

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 79


E-MTAB-11671_2:Sample 8

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 8

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: adenovirus infection

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 8


E-MTAB-11671_2:Sample 80

text: public

text: E-MTAB-11671_2:Sample 80

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 80


E-MTAB-11671_2:Sample 81

text: public

text: E-MTAB-11671_2:Sample 81

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 81

characteristic: title


E-MTAB-11671_2:Sample 82

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 82

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 82


E-MTAB-11671_2:Sample 83

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 83

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 83


E-MTAB-11671_2:Sample 84

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 84

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 84


E-MTAB-11671_2:Sample 85

text: public

text: E-MTAB-11671_2:Sample 85

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 85


E-MTAB-11671_2:Sample 86

text: public

text: E-MTAB-11671_2:Sample 86

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 86

characteristic: title


E-MTAB-11671_2:Sample 87

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 87

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 87


E-MTAB-11671_2:Sample 88

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 88

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 88


E-MTAB-11671_2:Sample 89

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 89

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 89


E-MTAB-11671_2:Sample 9

text: public

text: E-MTAB-11671_2:Sample 9

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: adenovirus infection

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: male

text: Sample 9


E-MTAB-11671_2:Sample 90

text: public

text: E-MTAB-11671_2:Sample 90

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 90

characteristic: title


E-MTAB-11671_2:Sample 91

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 91

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 91


E-MTAB-11671_2:Sample 92

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 92

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 92


E-MTAB-11671_2:Sample 93

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 93

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 93


E-MTAB-11671_2:Sample 94

text: public

text: E-MTAB-11671_2:Sample 94

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 94


E-MTAB-11671_2:Sample 95

text: public

text: E-MTAB-11671_2:Sample 95

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

characteristic: disease

text: Homo sapiens

text: Homo sapiens

text: blood

characteristic: organism part

text: Homo sapiens

text: female

characteristic: sex

text: Sample 95

characteristic: title


E-MTAB-11671_2:Sample 96

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: public

text: E-MTAB-11671_2:Sample 96

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 96


E-MTAB-11671_2:Sample 97

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

text: E-MTAB-11671_2:Sample 97

text: ArrayExpress

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 97


E-MTAB-11671_2:Sample 98

text: public

characteristic: SRA accession

text: E-MTAB-11671_2:Sample 98

characteristic: Submitter Id

characteristic: age

text: ArrayExpress

characteristic: broker name

text: human

text: juvenile stage

text: juvenile idiopathic arthritis

text: Homo sapiens

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 98


E-MTAB-11671_2:Sample 99

text: public

text: E-MTAB-11671_2:Sample 99

text: ArrayExpress

text: human

characteristic: common name

characteristic: description

text: juvenile stage

characteristic: developmental stage

text: juvenile idiopathic arthritis

text: Homo sapiens

characteristic: organism

text: Homo sapiens

text: blood

text: Homo sapiens

text: female

text: Sample 99


text: public

tag: Namespace:CENTRE FOR GENOMIC RESEARCH UNIVERSITY OF LIVERPOOL

text: Mediterranean fruit fly

text: Ceratitis capitata

text: Ceratitis capitata

characteristic: title


characteristic: ENA-CHECKLIST

text: CENTRE FOR GENOMIC RESEARCH UNIVERSITY OF LIVERPOOL

text: public

text: Mediterranean fruit fly

text: Ceratitis capitata

text: Ceratitis capitata


characteristic: ENA-FIRST-PUBLIC

text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2140

tag: Namespace:University of Birmingham

text: BCG grown for 8 hours in the presence of DMSO (1.25 %)

text: Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2


characteristic: ENA-LAST-UPDATE

text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2141


characteristic: External Id

text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2142


text: University of Birmingham

characteristic: INSDC center name

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2143


text: University of Birmingham

characteristic: INSDC first public

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2144

text: BCG grown for 8 hours in the presence of vanoxerine (15 microgram/ml)


text: University of Birmingham

characteristic: INSDC last update

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2145


text: University of Birmingham

text: public

characteristic: INSDC status

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2146


text: University of Birmingham

text: public

characteristic: SRA accession

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2147


text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2148

characteristic: Submitter Id

text: BCG grown for 8 hours in the presence of vanoxerine (30 microgram/ml)


text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2149


text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2150


text: University of Birmingham

text: public

text: ena-SAMPLE-TAB-21-11-2022-13:30:15:215-2151


text: DTU-GE

text: public

text: DTU-GE

text: Univeristy Teaching Hospital

text: Zambia

characteristic: geographic location (country and/or sea)

text: diseased

characteristic: host health state

text: Homo Sapiens

characteristic: host scientific name

characteristic: isolate

text: swab (wound)

text: Acinetobacter baumannii

text: NextSeq 500

text: Acinetobacter baumannii


text: DTU-GE

text: public

text: DTU-GE

characteristic: broker name

text: Quelimane Central Hospital - CISM

characteristic: description

text: Mozambique

text: diseased

text: Homo Sapiens

text: blood

text: Salmonella enterica

text: Illumina MiSeq

text: Salmonella enterica


text: DTU-GE

text: public

text: DTU-GE

text: Hospital of The Social Welfare Institute

text: Paraguay

text: diseased

text: Homo Sapiens

text: blood

text: Enterococcus faecium

characteristic: organism

text: Illumina MiSeq

text: Enterococcus faecium

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

text: National Institute of Public Health

text: public

tag: Namespace:National Institute of Public Health

characteristic: collection date

text: isolate

text: Czech Republic

text: not provided

text: Human

text: stool

text: Salmonella enterica subsp. enterica

text: Salmonella enterica subsp. enterica

text: Typhimurium monophasic

characteristic: serovar

characteristic: strain


characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: Wallenberg laboratory

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

tag: Namespace:Wallenberg laboratory

text: black rat

characteristic: common name

text: ileum

characteristic: environment (biome)

characteristic: environment (feature)

characteristic: environment (material)

text: metagenome

characteristic: investigation type

text: Rattus rattus

characteristic: project name

text: Rattus rattus

text: Illumina Solexa

characteristic: sequencing method


characteristic: ENA-CHECKLIST

text: Wallenberg laboratory

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: black rat

text: duodenum

characteristic: description

text: metagenome

text: Rattus rattus

characteristic: organism

text: Rattus rattus

text: Illumina Solexa

characteristic: title


characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: Wallenberg laboratory

characteristic: INSDC center name

text: public

text: black rat

text: jejunum

text: metagenome

text: Rattus rattus

text: Rattus rattus

text: Illumina Solexa


text: Wallenberg laboratory

characteristic: INSDC first public

characteristic: INSDC last update

text: public

text: black rat

characteristic: common name

text: feces

characteristic: environment (biome)

text: metagenome

text: Rattus rattus

text: Rattus rattus

text: Illumina Solexa


text: QUEEN MARY UNIVERSITY OF LONDON

text: public

tag: Namespace:QUEEN MARY UNIVERSITY OF LONDON

text: HiC library prepared with Omni-C Dovetail kit using an adult O. fusiformis

text: Owenia fusiformis

text: Owenia fusiformis

text: HiC of an adult O. fusiformis


text: QUEEN MARY UNIVERSITY OF LONDON

text: public

text: HiC library prepared with Omni-C Dovetail kit using sperm from an adult O. fusiformis

text: Owenia fusiformis

text: Owenia fusiformis

text: HiC of sperm of O. fusiformis


text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR6760055 of study ERP123933.

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

unit: DD

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Lachnospiraceae bacterium

text: Polycystic ovary syndrome (PCOS) impacts ~10% of reproductive-aged women worldwide. In addition to infertility, women with PCOS suffer from metabolic dysregulation which increases their risk of developing type 2 diabetes, cardiovascular disease and non-alcoholic fatty liver disease. Studies have shown differences in the gut microbiome of women with PCOS compared to women without the disorder, a pattern replicated in mouse models. Recently, using a letrozole-induced mouse model of PCOS, we demonstrated that cohousing was protective against development of both metabolic and reproductive phenotypes and showed via 16S amplicon sequencing that this protection correlated with time-dependent shifts in gut bacteria. Here, we applied untargeted metabolomics and shotgun metagenomics approaches to further analyze the longitudinal samples from the cohousing experiment. Analysis of beta diversity with the three ‘omics datasets found that untargeted metabolites had the strongest correlation to both disease and cohoused states and that shifts in metabolite diversity were detected prior to shifts in bacterial diversity. In addition, log2-fold analyses found numerous metabolite features, particularly bile acids (BA), to be highly differentiated between placebo (P) and letrozole (LET), as well as cohoused LET versus LET. Moreover, combination of BA and metagenomic features resulted in the best overall random forest classification accuracy, with BAs contributing the most to the classification accuracy. Our results indicate that changes in gut metabolites, particularly BAs, are associated with a PCOS-like phenotype in the LET mouse model as well as the protective effect of cohousing. Our results also suggest that transfer of metabolites via coprophagy occurs rapidly and may precipitate changes in bacterial diversity. This study joins a growing body of research highlighting changes in primary and secondary bile acids that may provide a link between host metabolism and gut microbes relevant to the pathology of PCOS.

characteristic: project name

characteristic: sample derived from

text: uncultured Lachnospiraceae bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760055_bin.13_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Porphyromonadaceae bacterium

characteristic: organism

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Porphyromonadaceae;g__;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760055_bin.2_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Clostridia bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760055_bin.20_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Angelakisella sp.

characteristic: organism

text: uncultured Angelakisella sp.

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Ruminococcaceae;g__Angelakisella;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760055_bin.27_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Clostridia bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Ruminococcaceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760055_bin.29_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Eubacterium sp.

characteristic: organism

text: uncultured Eubacterium sp.

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Eubacteriaceae;g__Eubacterium;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760055_bin.50_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: Mucispirillum schaedleri

characteristic: project name

characteristic: sample derived from

text: Mucispirillum schaedleri

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Deferribacteres;c__Deferribacteres;o__Deferribacterales;f__Deferribacteraceae;g__Mucispirillum;s__Mucispirillum schaedleri

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760055_bin.62_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

text: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR6760056 of study ERP123933.

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Porphyromonadaceae bacterium

characteristic: organism

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760056_bin.52_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR6760057 of study ERP123933.

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Muribaculaceae bacterium

text: Polycystic ovary syndrome (PCOS) impacts ~10% of reproductive-aged women worldwide. In addition to infertility, women with PCOS suffer from metabolic dysregulation which increases their risk of developing type 2 diabetes, cardiovascular disease and non-alcoholic fatty liver disease. Studies have shown differences in the gut microbiome of women with PCOS compared to women without the disorder, a pattern replicated in mouse models. Recently, using a letrozole-induced mouse model of PCOS, we demonstrated that cohousing was protective against development of both metabolic and reproductive phenotypes and showed via 16S amplicon sequencing that this protection correlated with time-dependent shifts in gut bacteria. Here, we applied untargeted metabolomics and shotgun metagenomics approaches to further analyze the longitudinal samples from the cohousing experiment. Analysis of beta diversity with the three ‘omics datasets found that untargeted metabolites had the strongest correlation to both disease and cohoused states and that shifts in metabolite diversity were detected prior to shifts in bacterial diversity. In addition, log2-fold analyses found numerous metabolite features, particularly bile acids (BA), to be highly differentiated between placebo (P) and letrozole (LET), as well as cohoused LET versus LET. Moreover, combination of BA and metagenomic features resulted in the best overall random forest classification accuracy, with BAs contributing the most to the classification accuracy. Our results indicate that changes in gut metabolites, particularly BAs, are associated with a PCOS-like phenotype in the LET mouse model as well as the protective effect of cohousing. Our results also suggest that transfer of metabolites via coprophagy occurs rapidly and may precipitate changes in bacterial diversity. This study joins a growing body of research highlighting changes in primary and secondary bile acids that may provide a link between host metabolism and gut microbes relevant to the pathology of PCOS.

characteristic: project name

characteristic: sample derived from

text: uncultured Muribaculaceae bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Muribaculaceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760057_bin.16_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: Faecalibaculum rodentium

characteristic: organism

text: Faecalibaculum rodentium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Erysipelotrichia;o__Erysipelotrichales;f__Erysipelotrichaceae;g__Faecalibaculum;s__Faecalibaculum rodentium

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760057_bin.24_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Porphyromonadaceae bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Porphyromonadaceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760057_bin.27_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Porphyromonadaceae bacterium

characteristic: organism

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760057_bin.53_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Porphyromonadaceae bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760057_bin.64_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Clostridia bacterium

characteristic: organism

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__;f__;g__;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760057_bin.66_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Porphyromonadaceae bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760057_bin.67_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Clostridia bacterium

characteristic: organism

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__;g__;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760057_bin.69_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Alistipes sp.

characteristic: project name

characteristic: sample derived from

text: uncultured Alistipes sp.

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Rikenellaceae;g__Alistipes;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760057_bin.72_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

text: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR6760057 of study ERP123933.

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Lactobacillus sp.

characteristic: organism

text: Polycystic ovary syndrome (PCOS) impacts ~10% of reproductive-aged women worldwide. In addition to infertility, women with PCOS suffer from metabolic dysregulation which increases their risk of developing type 2 diabetes, cardiovascular disease and non-alcoholic fatty liver disease. Studies have shown differences in the gut microbiome of women with PCOS compared to women without the disorder, a pattern replicated in mouse models. Recently, using a letrozole-induced mouse model of PCOS, we demonstrated that cohousing was protective against development of both metabolic and reproductive phenotypes and showed via 16S amplicon sequencing that this protection correlated with time-dependent shifts in gut bacteria. Here, we applied untargeted metabolomics and shotgun metagenomics approaches to further analyze the longitudinal samples from the cohousing experiment. Analysis of beta diversity with the three ‘omics datasets found that untargeted metabolites had the strongest correlation to both disease and cohoused states and that shifts in metabolite diversity were detected prior to shifts in bacterial diversity. In addition, log2-fold analyses found numerous metabolite features, particularly bile acids (BA), to be highly differentiated between placebo (P) and letrozole (LET), as well as cohoused LET versus LET. Moreover, combination of BA and metagenomic features resulted in the best overall random forest classification accuracy, with BAs contributing the most to the classification accuracy. Our results indicate that changes in gut metabolites, particularly BAs, are associated with a PCOS-like phenotype in the LET mouse model as well as the protective effect of cohousing. Our results also suggest that transfer of metabolites via coprophagy occurs rapidly and may precipitate changes in bacterial diversity. This study joins a growing body of research highlighting changes in primary and secondary bile acids that may provide a link between host metabolism and gut microbes relevant to the pathology of PCOS.

text: uncultured Lactobacillus sp.

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Bacilli;o__Lactobacillales;f__Lactobacillaceae;g__Lactobacillus;s__Lactobacillus reuteri

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760057_bin.8_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR6760058 of study ERP123933.

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Eubacterium sp.

characteristic: project name

characteristic: sample derived from

text: uncultured Eubacterium sp.

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Eubacteriaceae;g__Eubacterium;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760058_bin.20_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Clostridia bacterium

characteristic: organism

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760058_bin.22_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Tenericutes bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Tenericutes bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Tenericutes;c__;o__;f__;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760058_bin.31_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Porphyromonadaceae bacterium

characteristic: organism

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Porphyromonadaceae;g__;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760058_bin.4_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR6760059 of study ERP123933.

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Porphyromonadaceae bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Porphyromonadaceae bacterium

text: Illumina NovaSeq 6000

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760059_bin.21_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Clostridia bacterium

characteristic: organism

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__;f__;g__;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760059_bin.24_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Clostridia bacterium

text: Polycystic ovary syndrome (PCOS) impacts ~10% of reproductive-aged women worldwide. In addition to infertility, women with PCOS suffer from metabolic dysregulation which increases their risk of developing type 2 diabetes, cardiovascular disease and non-alcoholic fatty liver disease. Studies have shown differences in the gut microbiome of women with PCOS compared to women without the disorder, a pattern replicated in mouse models. Recently, using a letrozole-induced mouse model of PCOS, we demonstrated that cohousing was protective against development of both metabolic and reproductive phenotypes and showed via 16S amplicon sequencing that this protection correlated with time-dependent shifts in gut bacteria. Here, we applied untargeted metabolomics and shotgun metagenomics approaches to further analyze the longitudinal samples from the cohousing experiment. Analysis of beta diversity with the three ‘omics datasets found that untargeted metabolites had the strongest correlation to both disease and cohoused states and that shifts in metabolite diversity were detected prior to shifts in bacterial diversity. In addition, log2-fold analyses found numerous metabolite features, particularly bile acids (BA), to be highly differentiated between placebo (P) and letrozole (LET), as well as cohoused LET versus LET. Moreover, combination of BA and metagenomic features resulted in the best overall random forest classification accuracy, with BAs contributing the most to the classification accuracy. Our results indicate that changes in gut metabolites, particularly BAs, are associated with a PCOS-like phenotype in the LET mouse model as well as the protective effect of cohousing. Our results also suggest that transfer of metabolites via coprophagy occurs rapidly and may precipitate changes in bacterial diversity. This study joins a growing body of research highlighting changes in primary and secondary bile acids that may provide a link between host metabolism and gut microbes relevant to the pathology of PCOS.

characteristic: project name

characteristic: sample derived from

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760059_bin.37_metawrap_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaSPAdes v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: metawrap v1.3

characteristic: binning software

text: mouse digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

text: CheckM

characteristic: description

text: feces

text: USA

text: not provided

text: not provided

text: metagenome-assembled genome

text: mouse gut metagenome

text: digestive tube

text: mouse gut metagenome

text: uncultured Clostridia bacterium

characteristic: organism

text: uncultured Clostridia bacterium

text: Illumina NovaSeq 6000

characteristic: sequencing method

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Ruminococcaceae;g__;s__

text: multi-marker approach

text: Metagenome-assembled genome: ERR6760059_bin.44_metawrap_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

text: EMG

text: public

text: metaSPAdes v3.15.3

text: metawrap v1.3

text: mouse digestive system

text: EBI-EMG

characteristic: broker name

characteristic: collection date

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: feces

characteristic: environmental medium

text: USA

characteristic: geographic location (country and/or sea)

text: not provided

characteristic: geographic location (latitude)

text: not provided

characteristic: geographic location (longitude)

text: metagenome-assembled genome

characteristic: investigation type

text: mouse gut metagenome

text: digestive tube

characteristic: local environmental context

text: mouse gut metagenome

characteristic: metagenomic source

text: uncultured Lachnospiraceae bacterium

characteristic: project name

characteristic: sample derived from

text: uncultured Lachnospiraceae bacterium

text: Illumina NovaSeq 6000

text: The taxonomy of this metagenome-assembled genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-assembled genome: ERR6760059_bin.5_metawrap_v1.3_MAG