characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221352 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Sutterella sp.

characteristic: sample derived from

text: uncultured Sutterella sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Proteobacteria;c__Betaproteobacteria;o__Burkholderiales;f__Sutterellaceae;g__Sutterella;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221352_bin.20_MetaWRAP_v1.3_MAG

characteristic: title


status: PUBLIC

tag: attribute

characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221353 of study DRP008416.

text: faeces

text: China

unit: DD

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Opitutales bacterium

characteristic: organism

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: project name

text: uncultured Opitutales bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Verrucomicrobia;c__Opitutae;o__Opitutales;f__;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.1_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Lachnospiraceae bacterium

characteristic: sample derived from

text: uncultured Lachnospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__Anaerobutyricum;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.13_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Corallococcus sp.

characteristic: organism

characteristic: project name

text: uncultured Corallococcus sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Proteobacteria;c__Deltaproteobacteria;o__Myxococcales;f__Myxococcaceae;g__Corallococcus;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.24_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Bacteroides sp.

characteristic: sample derived from

text: uncultured Bacteroides sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Bacteroidaceae;g__Bacteroides;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.25_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Subdoligranulum sp.

characteristic: organism

characteristic: project name

text: uncultured Subdoligranulum sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__Subdoligranulum;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.28_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Ruminococcus sp.

characteristic: sample derived from

text: uncultured Ruminococcus sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__Ruminococcus;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.32_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Oscillospiraceae bacterium

characteristic: organism

characteristic: project name

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.36_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

text: metaspades v3.15.3

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Lachnospiraceae bacterium

characteristic: sample derived from

text: uncultured Lachnospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.37_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221353 of study DRP008416.

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacteriales bacterium

characteristic: organism

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: project name

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.38_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Oscillospiraceae bacterium

characteristic: sample derived from

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.4_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacteriales bacterium

characteristic: organism

characteristic: project name

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.40_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Lachnospiraceae bacterium

characteristic: sample derived from

text: uncultured Lachnospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.42_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacteriales bacterium

characteristic: organism

characteristic: project name

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.47_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Eubacteriales bacterium

characteristic: sample derived from

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.50_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Sutterella sp.

characteristic: organism

characteristic: project name

text: uncultured Sutterella sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Proteobacteria;c__Betaproteobacteria;o__Burkholderiales;f__Sutterellaceae;g__Sutterella;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.53_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Ruminococcus sp.

characteristic: sample derived from

text: uncultured Ruminococcus sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__Ruminococcus;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.55_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Methanomassiliicoccales archaeon

characteristic: organism

characteristic: project name

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Archaea;p__Candidatus Thermoplasmatota;c__Thermoplasmata;o__Methanomassiliicoccales;f__Methanomassiliicoccaceae;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221353_bin.58_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221353 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Eubacteriales bacterium

characteristic: sample derived from

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221353_bin.61_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221354 of study DRP008416.

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Collinsella sp.

characteristic: organism

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: project name

text: uncultured Collinsella sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Actinobacteria;c__Coriobacteriia;o__Coriobacteriales;f__Coriobacteriaceae;g__Collinsella;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221354_bin.27_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Oscillospiraceae bacterium

characteristic: sample derived from

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221354_bin.33_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Ruminococcus sp.

characteristic: organism

characteristic: project name

text: uncultured Ruminococcus sp.

text: Illumina HiSeq 3000

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221354_bin.43_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Oscillospiraceae bacterium

characteristic: sample derived from

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221354_bin.51_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Alistipes sp.

characteristic: organism

characteristic: project name

text: uncultured Alistipes sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Rikenellaceae;g__Alistipes;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221354_bin.7_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221355 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Cloacibacillus porcorum

characteristic: sample derived from

text: Cloacibacillus porcorum

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Synergistetes;c__Synergistia;o__Synergistales;f__Synergistaceae;g__Cloacibacillus;s__Cloacibacillus porcorum

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221355_bin.1_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacteriales bacterium

characteristic: organism

characteristic: project name

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221355_bin.17_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Klebsiella pneumoniae

characteristic: sample derived from

text: Klebsiella pneumoniae

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__Enterobacteriaceae;g__Klebsiella;s__Klebsiella pneumoniae

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221355_bin.19_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacteriales bacterium

characteristic: organism

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: project name

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221355_bin.23_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Megasphaera sp.

characteristic: sample derived from

text: uncultured Megasphaera sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Negativicutes;o__Veillonellales;f__Veillonellaceae;g__Megasphaera;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221355_bin.34_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Sutterella sp.

characteristic: organism

characteristic: project name

text: uncultured Sutterella sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Proteobacteria;c__Betaproteobacteria;o__Burkholderiales;f__Sutterellaceae;g__Sutterella;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221355_bin.7_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221356 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Lachnospira eligens

characteristic: sample derived from

text: Lachnospira eligens

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__Lachnospira;s__Lachnospira eligens

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221356_bin.14_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Lachnospiraceae bacterium

characteristic: organism

characteristic: project name

text: uncultured Lachnospiraceae bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221356_bin.28_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Eubacterium ventriosum

characteristic: sample derived from

text: Eubacterium ventriosum

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Eubacteriaceae;g__Eubacterium;s__Eubacterium ventriosum

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221356_bin.29_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Alistipes sp.

characteristic: organism

characteristic: project name

text: uncultured Alistipes sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Rikenellaceae;g__Alistipes;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221356_bin.30_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Bifidobacterium adolescentis

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: sample derived from

text: Bifidobacterium adolescentis

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Actinobacteria;c__Actinomycetia;o__Bifidobacteriales;f__Bifidobacteriaceae;g__Bifidobacterium;s__Bifidobacterium adolescentis

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221356_bin.34_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Roseburia sp.

characteristic: organism

characteristic: project name

text: uncultured Roseburia sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__Roseburia;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221356_bin.37_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221357 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Oscillospiraceae bacterium

characteristic: sample derived from

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221357_bin.11_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured bacterium

characteristic: organism

characteristic: project name

text: uncultured bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__;c__;o__;f__;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221357_bin.2_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Clostridium sp.

characteristic: sample derived from

text: uncultured Clostridium sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Clostridiaceae;g__Clostridium;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221357_bin.20_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Oscillospiraceae bacterium

characteristic: organism

characteristic: project name

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221357_bin.25_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Oscillospiraceae bacterium

characteristic: sample derived from

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221357_bin.3_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: Prevotella copri

characteristic: organism

characteristic: project name

text: Prevotella copri

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Prevotellaceae;g__Prevotella;s__Prevotella copri

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221357_bin.34_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Clostridium sp.

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: sample derived from

text: uncultured Clostridium sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221357_bin.38_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacterium sp.

characteristic: organism

characteristic: project name

text: uncultured Eubacterium sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Eubacteriaceae;g__Eubacterium;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221357_bin.40_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221357 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Firmicutes bacterium

characteristic: sample derived from

text: uncultured Firmicutes bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__;o__;f__;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221357_bin.42_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacteriales bacterium

characteristic: organism

characteristic: project name

text: uncultured Eubacteriales bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221357_bin.50_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Clostridium sp.

characteristic: sample derived from

text: uncultured Clostridium sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221357_bin.53_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221358 of study DRP008416.

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: Ruminococcus bromii

characteristic: organism

characteristic: project name

text: Ruminococcus bromii

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__Ruminococcus;s__Ruminococcus bromii

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221358_bin.12_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Faecalibacterium sp.

characteristic: sample derived from

text: uncultured Faecalibacterium sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__Faecalibacterium;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221358_bin.14_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: Blautia wexlerae

characteristic: organism

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: project name

text: Blautia wexlerae

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__Blautia;s__Blautia wexlerae

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221358_bin.16_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Gemmiger sp.

characteristic: sample derived from

text: uncultured Gemmiger sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__;g__Gemmiger;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221358_bin.21_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Ruminococcus sp.

characteristic: organism

characteristic: project name

text: uncultured Ruminococcus sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__Ruminococcus;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221358_bin.45_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Plesiomonas shigelloides

characteristic: sample derived from

text: Plesiomonas shigelloides

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Proteobacteria;c__Gammaproteobacteria;o__Enterobacterales;f__;g__Plesiomonas;s__Plesiomonas shigelloides

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221358_bin.47_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Prevotella sp.

characteristic: organism

characteristic: project name

text: uncultured Prevotella sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Bacteroidetes;c__Bacteroidia;o__Bacteroidales;f__Prevotellaceae;g__Prevotella;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221358_bin.48_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221358 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: Streptococcus thermophilus

characteristic: sample derived from

text: Streptococcus thermophilus

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Bacilli;o__Lactobacillales;f__Streptococcaceae;g__Streptococcus;s__Streptococcus thermophilus

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221358_bin.7_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Eubacterium sp.

characteristic: organism

characteristic: project name

text: uncultured Eubacterium sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Eubacteriaceae;g__Eubacterium;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221358_bin.9_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221359 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Eubacterium sp.

text: Diabetic peripheral neuropathy (DPN) is one of the serious and long-term complications of diabetes mellitus, which has no modifiable treatment. Here we reported the results of using fecal microbiota transplantation (FMT) from the healthy donors as a therapeutic alternative for patients with DPN. Compared to the patients received placebo, the patients with FMT via mid-gut showed significant alleviation of the function of sensory and motor nerves after 12 weeks, accompanying with improvement of the gut barrier integrity and decrease of proinflammatory cytokines. The metagenomic sequencing data suggested that the gut microbiota in patients after FMT had higher capacity to produce butyrate and decreased the biosynthesis of endotoxin. Thus, our work provides the feasibility of using FMT to treatment for DPN.

characteristic: sample derived from

text: uncultured Eubacterium sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221359_bin.17_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Oscillospiraceae bacterium

characteristic: organism

characteristic: project name

text: uncultured Oscillospiraceae bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Oscillospiraceae;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221359_bin.22_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Eubacterium sp.

characteristic: sample derived from

text: uncultured Eubacterium sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221359_bin.23_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: Holdemanella biformis

characteristic: organism

characteristic: project name

text: Holdemanella biformis

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Erysipelotrichia;o__Erysipelotrichales;f__Erysipelotrichaceae;g__Holdemanella;s__Holdemanella biformis

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221359_bin.29_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: Many fragments with little to no review of assembly other than reporting of standard assembly statistics

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Clostridiaceae bacterium

characteristic: sample derived from

text: uncultured Clostridiaceae bacterium

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Clostridiaceae;g__;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221359_bin.39_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Clostridium sp.

characteristic: organism

characteristic: project name

text: uncultured Clostridium sp.

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Clostridiaceae;g__Clostridium;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221359_bin.51_MetaWRAP_v1.3_MAG


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

text: public

text: metaspades v3.15.3

text: MetaWRAP v1.3

text: Human digestive system

text: EBI-EMG

characteristic: collection date

characteristic: common name

characteristic: completeness score

text: CheckM

characteristic: completeness software

characteristic: contamination score

text: This sample represents a Third Party Annotation (TPA) metagenome-assembled genome assembled from the metagenomic run DRR221360 of study DRP008416.

characteristic: description

text: faeces

characteristic: environmental medium

text: China

characteristic: geographic location (country and/or sea)

text: metagenome-assembled genome

characteristic: investigation type

text: human feces metagenome

text: colon

characteristic: local environmental context

text: human feces metagenome

characteristic: metagenomic source

text: uncultured Blautia sp.

characteristic: sample derived from

text: uncultured Blautia sp.

text: Illumina HiSeq 3000

characteristic: sequencing method

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__Clostridia;o__Eubacteriales;f__Lachnospiraceae;g__Blautia;s__

characteristic: taxonomic classification

text: multi-marker approach

characteristic: taxonomic identity marker

text: Metagenome-Assembled Genome: DRR221360_bin.12_MetaWRAP_v1.3_MAG

characteristic: title


characteristic: ENA-CHECKLIST

characteristic: ENA-FIRST-PUBLIC

characteristic: ENA-LAST-UPDATE

characteristic: External Id

text: EMG

characteristic: INSDC center name

characteristic: INSDC first public

characteristic: INSDC last update

text: public

characteristic: INSDC status

characteristic: SRA accession

characteristic: Submitter Id

characteristic: assembly quality

text: metaspades v3.15.3

characteristic: assembly software

text: MaxBin2, MetaBat2, Concoct with default parameter of the metaWRAP pipeline. Bin refinement module used from metaWRAP with default parameters.

characteristic: binning parameters

text: MetaWRAP v1.3

characteristic: binning software

text: Human digestive system

characteristic: broad-scale environmental context

text: EBI-EMG

characteristic: broker name

text: CheckM

text: faeces

text: China

characteristic: geographic location (latitude)

characteristic: geographic location (longitude)

text: metagenome-assembled genome

text: human feces metagenome

text: colon

text: human feces metagenome

text: uncultured Firmicutes bacterium

characteristic: organism

characteristic: project name

text: uncultured Firmicutes bacterium

text: Illumina HiSeq 3000

text: The taxonomy of this Metagenome-Assembled Genome was originally computed with GTDBtk, which assigned the following taxonomic annotation: d__Bacteria;p__Firmicutes;c__;o__;f__;g__;s__

text: multi-marker approach

text: Metagenome-Assembled Genome: DRR221360_bin.20_MetaWRAP_v1.3_MAG