title: IRCL Human Genome CGH Microarray 44B G4410B (probe version)
status: Public on Dec 16 2009
contact.city: lille
contact.first: frédéric
contact.last: leprêtre
contact.email: frederic.lepretre@univ-lille.fr
contact.address: Boulevard du Pr Leclercq
contact.department: CHU of Lille, CBP
contact.country: France
contact.institute: Lille University
organism: Homo sapiens
description: Human Genome CGH Microarray 44B, high-resolution, high performance 60-mer oligonucleotide, allowing genome-wide survey and molecular profiling of DNA copy number changes on a single chip.  It provides comprehensive genome-wide coverage with emphasis on the most commonly studied genomic regions and cancer-related genes.  It consists of ~43,000 60-mer oligonucleotide probes, empirically validated in multiple model systems, spanning coding and noncoding sequences with average spatial resolution of 35kb.  It replaces 44A (G4410A), includes all biological probes from 44A, mapped to the latest NCBI build, 35), plus an additional ~ 2,500 probes to expand coverage in the human genome.  Agilent has taken extra measures to design the microarray that truly represents the coverage and performance needed for this application.  Agilent has developed and optimized assay protocols that enable researchers to use nanogram levels of total genomic DNA without genome complexity reduction.
  
  Arrays of this design have barcodes that begin with 16013282 or 2513282.
  
manufacture_protocol: see manufacturer's web site at http://www.agilent.com/