title: SuperArray GEArray Q Series Human Androgen Signaling and Prostate Cancer Gene Array
status: Public on Apr 09 2004
contact.city: Frederick
contact.first: SuperArray
contact.last: Bioscience Corporation
contact.email: support@superarray.net
contact.state: MD
contact.address: Suite 101, 7320 Executive Way
contact.country: USA
contact.institute: Technical Support
contact.phone: 301-682-9200
organism: Homo sapiens
description: GEArray Q Series Androgen Signaling and Prostate Cancer Gene Array is designed to assess the role of 96 genes in androgen-regulated processes that are involved in malignant transformation of prostate gland. Androgen signaling plays an important role in the pathogenesis of prostate cancer, as exemplified by androgen ablation therapy for advanced prostate cancer. Activation of the PI3K/AKT/FRAP pathway has also been found to contribute to hormone resistant growth of recurrent prostate cancer. On the Androgen Signaling and Prostate Cancer Gene Array, 96 prostate cancer-related genes have been grouped into the following categories: androgen receptor and androgen receptor-associated proteins, androgen exclusively-responsive genes, androgen-independent genes, target genes whose responsiveness to androgen changes during the course of prostate malignant transformation, PI3K/AKT/FRAP pathway related genes that are associated with hormone-refractory cell growth, and genes associated with invasive prostate cancer.
  Catalog number HS-031 (Superarray, Frederick, MD)
  Platform_weblink: http://www.superarray.com/home.php
manufacture_protocol: see manufacturer's web site