title: SuperArray GEArray Q Series Human Stress Response to Cellular Damage Gene Array
status: Public on Apr 09 2004
contact.city: Frederick
contact.first: SuperArray
contact.last: Bioscience Corporation
contact.email: support@superarray.net
contact.state: MD
contact.address: Suite 101, 7320 Executive Way
contact.country: USA
contact.institute: Technical Support
contact.phone: 301-682-9200
organism: Homo sapiens
description: The GEArray Q Series Human Stress Response to Cellular Damage Gene Array is designed to systematically analyze the cellular stress response by profiling the expression level of genes encoding antioxidant and pro-oxidant enzymes, molecular chaperones and proteins involved in xenobiotic metabolism. Oxidative stress, hyperthermia, exercise, metabolic challenge, and aging are the major sources of stress that cause cellular damage. Prolonged and uncontrolled cellular damage contributes to a variety of diseases including atherosclerosis, diabetes, pulmonary fibrosis, neurodegeneration, and arthritis. To control and repair damage, cells respond to stress by increasing the expression of antioxidant enzymes to combat oxidative stress, chaperones and heat shock proteins to refold or sequester damaged proteins, and xenobiotic enzymes and transporters to eliminate foreign, unwanted and potentially cytotoxic molecules. This GEArray allows you to monitor the responses to specific stresses by detecting differences in the expression level of these genes between stressed and unstressed cells.
  Catalog number HS-053 (Superarray, Frederick, MD)
  Platform_weblink: http://www.superarray.com/home.php
manufacture_protocol: see manufacturer's web site