title: SuperArray GEArray Q Series Human Insulin Signaling Pathway Gene Array
status: Public on Apr 09 2004
contact.city: Frederick
contact.first: SuperArray
contact.last: Bioscience Corporation
contact.email: support@superarray.net
contact.state: MD
contact.address: Suite 101, 7320 Executive Way
contact.country: USA
contact.institute: Technical Support
contact.phone: 301-682-9200
organism: Homo sapiens
description: GEArray Q Series Human Insulin Signaling Pathway Gene Array is designed to assess the role of insulin-responsive genes in your experimental system. Insulin mediates a wide spectrum of biological responses associated with glucose uptake, glycogen, lipid and protein synthesis, transcriptional activation, cell growth and differentiation. Dysfunctional insulin signaling results in insulin resistance that is associated with diabetes, obesity, hypertension and cardiovascular disease. The GEArray Q Series Human Insulin Signaling Pathway Gene Array includes 96 key genes that are grouped into the following categories: the PI 3-kinase pathway, targets of the PI 3-kinase pathway, the MAPK pathway, targets of the MAPK pathway, primary insulin target genes, secondary insulin target genes, target genes associated with the insulin sensitizer, PPARg, and targets of the insulin-activated transcription factor, SREBP. These functional groupings allow the researcher to conveniently identify the activation of insulin-associated pathways and to obtain a "molecular signature" under their specific experimental conditions.
  Catalog number HS-030 (Superarray, Frederick, MD)
  Platform_weblink: http://www.superarray.com/home.php
manufacture_protocol: see manufacturer's web site