title: Cerebellargenexp
status: Public on Apr 18 2001
contact.city: Wako-shi
contact.first: Yoshihiro
contact.last: Kagami
contact.email: ykagami@brain.riken.go.jp
contact.state: Saitama
contact.address: 2-1 Hirosawa
contact.country: Japan
contact.web_link: http://www.brain.riken.go.jp/labs/lmn
contact.institute: RIKEN Brain Science Institute
contact.phone: +81-48-467-6079
organism: Mus musculus
description: The Affymetrix GeneChip Mu11K was used to analyze the gene expression profile in developing mouse cerebellum (two GeneChips per E18, P7, P14, P21, and P56) to assist in the understanding of the genetic basis of cerebellar development in mice.  The analysis showed 81.6% (10,321/12,654) of the genes represented on the GeneChip were expressed in the postnatal cerebellum, and among those, 8.7% (897/10,321) were differentially expressed with more than a two-fold change in their maximum and minimum expression levels during the developmental time course.  All of these 897 differentially expressed genes were listed in this platform.  The explanation of gene function classification is as follows:  CGDD (cellular growth, differentiation, and death), CLAM (carbohydrate, lipid, and amino acid metabolism), CSC (cell structure and communication), IMTN (intra/intercellular molecular transport and neurotransmission), NNM (nucleotide and nucleic acid metabolism), ST (signal transduction), and TTPM (transcription, translation, and protein modification).
  Keywords = cerebellum, postnatal development, high-density oligonucleotide array