title: Pathway analysis of primary central nervous system lymphoma (PCNSL)

status: Public on May 10 2008

city: Boston

first: Peter

last: Park

state: MA

address: 10 Shattuck St

department: Center for Biomedical Informatics

institute: Harvard Medical School

summary:
Primary central nervous system (CNS) lymphoma (PCNSL) is a diffuse large B cell lymphoma (DLBCL) confined to the CNS. A genome-wide gene expression comparison between PCNSL and non-CNS DLBCL was performed, the latter consisting of both nodal and extranodal DLBCL (nDLBCL and enDLBCL), to identify a “CNS signature.”
Keywords: disease state analysis

overall_design: Three-condition experiment: PCNSL vs. nDLBCL and enDLBCL. Biological replicates: 13 PCNSL, 19 enDLBCL, 11 nDLBCL. Common reference on all arrays. No dye-swaps. One replicate per array.