title: KD3033 SA 22d

description:
Whole blood RNA (PAXgene tubes) was collected from 20 Kawasaki patients during the acute, sub-acute (post-IVIG treatment) and convalescent phases of the disease
Image: http://smd.stanford.edu/MicroArray/gifs/2003-05/40531.gif
Measurement: time(relative) 22 d
Individual: KD3033

scan_protocol: Feature Extraction; Software and parameters for feature extraction.; Protocol Type = Feature Extraction; Parameter Image Origin = 1420, 6510; Parameter Datafile type = GenePix Results 3; Software: type: feature extraction; Performer: Stephen,,Popper Scanning parameters - Channel 1; Parameters for laser scanning of a hybridized array in channel 1.; Protocol Type = Scanning parameters; Parameter Scanner Make = Axon Instruments (V1.00); Parameter Scan Temperature = 39.26; Parameter Scan Time = 11:05:02; Parameter PMT Volts = 650; Parameter Scan Date = 2003-05-01; Parameter Pixel Size = 10; Parameter Laser on time = 92998; Parameter Focus Position = 0; Parameter Scanner Model = GenePix 4000A [47263]; Parameter Laser Power = 1.34; Parameter Scan Power = 100; Parameter Scanning software version = 2.0.2.3; Parameter Scanning software = AxImageIO; Performer: Stephen,,Popper Scanning parameters - Channel 2; Parameters for laser scanning of a hybridized array in channel 2.; Protocol Type = Scanning parameters; Parameter Scanner Make = Axon Instruments (V1.00); Parameter Scan Temperature = 39.26; Parameter Scan Time = 11:05:02; Parameter PMT Volts = 710; Parameter Scan Date = 2003-05-01; Parameter Pixel Size = 10; Parameter Laser on time = 458106; Parameter Focus Position = 0; Parameter Scanner Model = GenePix 4000A [47263]; Parameter Laser Power = 2.27; Parameter Scanning software version = 2.0.2.3; Parameter Scan Power = 100; Parameter Scanning software = AxImageIO; Performer: Stephen,,Popper

value: time(relative) 22 d

source_name: KD 3033 21d Paxgene Ambion amp 4ug


title: Day  238 control 4

status: Public on Dec 11 2007

type: RNA

city: Horsham

first: Christopher

middle: S

last: Stevenson

address: Wimblehurst Road

department: Respiratory Diseases

country: United Kingdom

institute: Novartis Institutes for BioMedical Research

description: rat lung, day238, ctrl

hyb_protocol: Standard Affymetrix protocol

scan_protocol: Standard Affymetrix protocol

data_processing: The data was analyzed with Microarray Suite version 5.0 (MAS 5.0) using Affymetrix default analysis settings and global scaling of as normalization method. The trimmed mean target intensity of each array was set to 150.

label: biotin

molecule: total RNA

organism: Rattus norvegicus

source_name: rat lung, day238, ctrl

label_protocol: Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 10 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix)

extract_protocol: Trizol extraction of total RNA was performed according to the manufacturers instructions.

tag: Strain

value: SD

tag: Gender

value: Male

tag: Tissue

value: Lung


title: Day 238 cessation smoke exposure 4

description: rat lung, day238, cess smoke

source_name: rat lung, day238, cess smoke


title: Day  238 cessation control 7

description: rat lung, day238, cess ctrl

source_name: rat lung, day238, cess ctrl


title: Day 238 cessation smoke exposure 6

description: rat lung, day238, cess smoke


title: Day 238 cessation smoke exposure 8

description: rat lung, day238, cess smoke


title: Day  238 control 1

description: rat lung, day238, ctrl


title: Day 238 cessation smoke exposure 3

description: rat lung, day238, cess smoke


title: Day 238 cessation smoke exposure 7

description: rat lung, day238, cess smoke


title: Day  238 cessation control 2

description: rat lung, day238, cess ctrl


title: Day 182 smoke exposure 7

description: rat lung, day182, smoke

source_name: rat lung, day182, smoke


title: Day 238 cessation smoke exposure 1

description: rat lung, day238, cess smoke


title: Day  238 cessation control 4

description: rat lung, day238, cess ctrl


title: Day  238 control 2

description: rat lung, day238, ctrl


title: Day  238 control 3

description: rat lung, day238, ctrl


title: Day  238 cessation control 6

description: rat lung, day238, cess ctrl


title: Day  238 cessation control 1

description: rat lung, day238, cess ctrl


title: Day  238 cessation control 3

description: rat lung, day238, cess ctrl


title: Day 238 cessation smoke exposure 2

description: rat lung, day238, cess smoke


title: Day  238 cessation control 5

description: rat lung, day238, cess ctrl


title: Day 182 smoke exposure 9

description: rat lung, day182, smoke


title: Day 182 smoke exposure 4

description: rat lung, day182, smoke


title: Day 182 smoke exposure 8

description: rat lung, day182, smoke


title: Day 182 smoke exposure 3

description: rat lung, day182, smoke


title: Day 182 smoke exposure 6

description: rat lung, day182, smoke


title: Day 182 smoke exposure 5

description: rat lung, day182, smoke


title: Day 182 control 5

description: rat lung, day182, ctrl

source_name: rat lung, day182, ctrl


title: Day 182 control 8

description: rat lung, day182, ctrl


title: Day 182 control 7

description: rat lung, day182, ctrl


title: Day 182 smoke exposure 2

description: rat lung, day182, smoke


title: Day 182 control 6

description: rat lung, day182, ctrl


title: Day 182 control 2

description: rat lung, day182, ctrl


title: Day 182 control 1

description: rat lung, day182, ctrl


title: Day 112 control 7

description: rat lung, day112, ctrl

source_name: rat lung, day112, ctrl


title: Day 112 smoke exposure 7

description: rat lung, day112, smoke

source_name: rat lung, day112, smoke


title: Day 112 smoke exposure 4

description: rat lung, day112, smoke


title: Day 112 smoke exposure 3

description: rat lung, day112, smoke


title: Day 182 control 4

description: rat lung, day182, ctrl


title: Day 182 control 3

description: rat lung, day182, ctrl


title: Day 112 control 8

description: rat lung, day112, ctrl


title: Day 112 smoke exposure 2

description: rat lung, day112, smoke


title: Day 112 smoke exposure 5

description: rat lung, day112, smoke


title: Day 112 smoke exposure 6

description: rat lung, day112, smoke


title: Day 112 control 6

description: rat lung, day112, ctrl


title: Day 182 smoke exposure 1

description: rat lung, day182, smoke


title: Day 112 control 4

description: rat lung, day112, ctrl


title: Day 112 control 1

description: rat lung, day112, ctrl


title: Day 112 smoke exposure 1

description: rat lung, day112, smoke


title: Day 112 control 5

description: rat lung, day112, ctrl


title: Day 84 smoke exposure 6

description: rat lung, day84, smoke

source_name: rat lung, day84, smoke


title: Day 112 control 3

description: rat lung, day112, ctrl


title: Day 84 smoke exposure 7

description: rat lung, day84, smoke


title: Day 84 smoke exposure 5

description: rat lung, day84, smoke


title: Day 84 smoke exposure 8

description: rat lung, day84, smoke


title: Day 84 smoke exposure 3

description: rat lung, day84, smoke


title: Day 112 control 2

description: rat lung, day112, ctrl


title: Day 84 smoke exposure 2

description: rat lung, day84, smoke


title: Day 84 smoke exposure 4

description: rat lung, day84, smoke


title: Day 84 smoke exposure 1

description: rat lung, day84, smoke


title: Day 84 control 7

description: rat lung, day84, ctrl

source_name: rat lung, day84, ctrl


title: Day 84 control 6

description: rat lung, day84, ctrl


title: Day 84 control 4

description: rat lung, day84, ctrl


title: Day 84 control 5

description: rat lung, day84, ctrl


title: Day 56 smoke exposure 4

description: rat lung, day56, smoke

source_name: rat lung, day56, smoke


title: Day 56 smoke exposure 5

description: rat lung, day56, smoke


title: Day 56 smoke exposure 8

description: rat lung, day56, smoke


title: Day 84 control 2

description: rat lung, day84, ctrl


title: Day 56 control 6

description: rat lung, day56, ctrl

source_name: rat lung, day56, ctrl


title: Day 56 smoke exposure 1

description: rat lung, day56, smoke


title: Day 56 smoke exposure 3

description: rat lung, day56, smoke


title: Day 84 control 1

description: rat lung, day84, ctrl


title: Day 56 control 7

description: rat lung, day56, ctrl


title: Day 56 smoke exposure 6

description: rat lung, day56, smoke


title: Day 84 control 8

description: rat lung, day84, ctrl


title: Day 56 smoke exposure 2

description: rat lung, day56, smoke


title: Day 84 control 3

description: rat lung, day84, ctrl


title: Day 56 control 8

description: rat lung, day56, ctrl


title: Day 56 control 1

description: rat lung, day56, ctrl


title: Day 42 smoke exposure 8

description: rat lung, day42, smoke

source_name: rat lung, day42, smoke


title: Day 56 smoke exposure 7

description: rat lung, day56, smoke


title: Day 56 control 3

description: rat lung, day56, ctrl


title: Day 42 smoke exposure 7

description: rat lung, day42, smoke


title: Day 56 control 4

description: rat lung, day56, ctrl


title: Day 42 smoke exposure 6

description: rat lung, day42, smoke


title: Day 42 smoke exposure 4

description: rat lung, day42, smoke


title: Day 56 control 5

description: rat lung, day56, ctrl


title: Day 42 smoke exposure 5

description: rat lung, day42, smoke


title: Day 42 control 3

description: rat lung, day42, ctrl

source_name: rat lung, day42, ctrl


title: Day 42 control 6

description: rat lung, day42, ctrl


title: Day 42 control 8

description: rat lung, day42, ctrl


title: Day 42 control 2

description: rat lung, day42, ctrl


title: Day 42 control 4

description: rat lung, day42, ctrl


title: Day 56 control 2

description: rat lung, day56, ctrl


title: Day 28 control 6

description: rat lung, day28, ctrl

source_name: rat lung, day28, ctrl


title: Day 42 smoke exposure 1

description: rat lung, day42, smoke


title: Day 3 control 9

description: rat lung, day3, ctrl

source_name: rat lung, day3, ctrl


title: Day 28 smoke exposure 6

description: rat lung, day28, smoke

source_name: rat lung, day28, smoke


title: Day 42 control 7

description: rat lung, day42, ctrl


title: Day 21 smoke exposure 8

description: rat lung, day21, smoke

source_name: rat lung, day21, smoke


title: Day 42 smoke exposure 2

description: rat lung, day42, smoke


title: Day 28 smoke exposure 8

description: rat lung, day28, smoke


title: Day 21 control 8

description: rat lung, day21, ctrl

source_name: rat lung, day21, ctrl


title: Day 42 control 5

description: rat lung, day42, ctrl


title: Day 28 control 7

description: rat lung, day28, ctrl


title: Day 28 smoke exposure 7

description: rat lung, day28, smoke


title: Day 42 control 1

description: rat lung, day42, ctrl


title: Day 42 smoke exposure 3

description: rat lung, day42, smoke


title: Day 21 smoke exposure 6

description: rat lung, day21, smoke


title: Day 28 control 8

description: rat lung, day28, ctrl


title: Day 21 control 6

description: rat lung, day21, ctrl


title: Day 21 smoke exposure 7

description: rat lung, day21, smoke


title: Day 21 control 7

description: rat lung, day21, ctrl


title: Day 14 smoke exposure 8

description: rat lung, day14, smoke

source_name: rat lung, day14, smoke


title: Day 14 smoke exposure 7

description: rat lung, day14, smoke


title: Day 14 control 6

description: rat lung, day14, ctrl

source_name: rat lung, day14, ctrl


title: Day 14 smoke exposure 6

description: rat lung, day14, smoke


title: Day 14 control 7

description: rat lung, day14, ctrl


title: Day 14 control 8

description: rat lung, day14, smoke


title: Day 5 smoke exposure 8

description: rat lung, day5, smoke

source_name: rat lung, day5, smoke


title: Day 14 smoke exposure 5

description: rat lung, day14, smoke


title: Day 5 smoke exposure 7

description: rat lung, day5, smoke


title: Day 5 control 7

description: rat lung, day5, ctrl

source_name: rat lung, day5, ctrl


title: Day 3 control 8

description: rat lung, day3, ctrl


title: Day 5 control 8

description: rat lung, day5, ctrl


title: Day 1 smoke exposure 8

description: rat lung, day1, smoke

source_name: rat lung, day1, smoke


title: Day 3 smoke exposure 7

description: rat lung, day3, smoke

source_name: rat lung, day3, smoke


title: Day 1 control 7

description: rat lung, day1, ctrl

source_name: rat lung, day1, ctrl


title: Day 1 smoke exposure 7

description: rat lung, day1, smoke


title: Day 3 smoke exposure 8

description: rat lung, day3, smoke


title: Day 28 smoke exposure 5

description: rat lung, day28, smoke


title: Day 3 control 7

description: rat lung, day3, ctrl


title: Day 28 smoke exposure 4

description: rat lung, day28, smoke


title: Day 28 control 4

description: rat lung, day28, ctrl


title: Day 21 smoke exposure 5

description: rat lung, day21, smoke


title: Day 21 control 5

description: rat lung, day21, ctrl


title: Day 28 control 5

description: rat lung, day28, ctrl


title: Day 21 smoke exposure 4

description: rat lung, day21, smoke


title: Day 5 smoke exposure 5

description: rat lung, day5, smoke


title: Day 1 control 8

description: rat lung, day1, ctrl


title: Day 14 control 4

description: rat lung, day14, ctrl


title: Day 14 control 5

description: rat lung, day14, ctrl


title: Day 21 control 4

description: rat lung, day21, ctrl


title: Day 5 control 5

description: rat lung, day5, ctrl


title: Day 5 smoke exposure 4

description: rat lung, day5, smoke


title: Day 5 smoke exposure 6

description: rat lung, day5, smoke


title: Day 3 smoke exposure 5

description: rat lung, day3, smoke


title: Day 1 control 6

description: rat lung, day1, ctrl


title: Day 1 smoke exposure 6

description: rat lung, day1, smoke


title: Day 5 control 6

description: rat lung, day5, ctrl


title: Day 5 control 4

description: rat lung, day5, ctrl


title: Day 14 smoke exposure 3

description: rat lung, day14, smoke


title: Day 1 smoke exposure 5

description: rat lung, day1, smoke


title: Day 3 smoke exposure 6

description: rat lung, day3, smoke


title: Day 14 smoke exposure 4

description: rat lung, day14, smoke


title: Day 3 smoke exposure 4

description: rat lung, day3, smoke


title: Day 3 control 6

description: rat lung, day3, ctrl


title: Day 1 smoke exposure 4

description: rat lung, day1, smoke


title: Day 3 control 4

description: rat lung, day3, ctrl


title: Day 28 smoke exposure 3

description: rat lung, day28, smoke


title: Day 3 control 5

description: rat lung, day3, ctrl


title: Day 1 control 5

description: rat lung, day1, ctrl


title: Day 1 control 4

description: rat lung, day1, ctrl


title: Day 28 smoke exposure 2

description: rat lung, day28, smoke


title: Day 28 control 3

description: rat lung, day28, ctrl


title: Day 28 control 1

description: rat lung, day28, ctrl


title: Day 21 control 2

description: rat lung, day21, ctrl


title: Day 5 smoke exposure 3

description: rat lung, day5, smoke


title: Day 21 smoke exposure 1

description: rat lung, day21, smoke


title: Day 21 smoke exposure 3

description: rat lung, day21, smoke


title: Day 28 smoke exposure 1

description: rat lung, day28, smoke


title: Day 5 control 3

description: rat lung, day5, ctrl


title: Day 14 control 2

description: rat lung, day14, ctrl


title: Day 21 smoke exposure 2

description: rat lung, day21, smoke


title: Day 28 control 2

description: rat lung, day28, ctrl


title: Day 5 smoke exposure 2

description: rat lung, day5, smoke


title: Day 14 smoke exposure 1

description: rat lung, day14, smoke


title: Day 14 control 3

description: rat lung, day14, ctrl


title: Day 21 control 1

description: rat lung, day21, ctrl


title: Day 1 smoke exposure 2

description: rat lung, day1, smoke


title: Day 21 control 3

description: rat lung, day21, ctrl


title: Day 3 smoke exposure 3

description: rat lung, day3, smoke


title: Day 3 control 2

description: rat lung, day3, ctrl


title: Day 14 smoke exposure 2

description: rat lung, day14, smoke


title: Day 1 control 3

description: rat lung, day1, ctrl


title: Day 1 control 2

description: rat lung, day1, ctrl


title: Day 5 control 2

description: rat lung, day5, ctrl


title: Day 1 smoke exposure 3

description: rat lung, day1, smoke


title: Day 3 control 3

description: rat lung, day3, ctrl


title: Day 14 control 1

description: rat lung, day14, ctrl


title: Day 3 smoke exposure 2

description: rat lung, day3, smoke


title: Day 5 smoke exposure 1

description: rat lung, day5, smoke


title: Day 1 smoke exposure 1

description: rat lung, day1, smoke


title: Day 5 control 1

description: rat lung, day5, ctrl


title: Day 1 control 1

description: rat lung, day1, ctrl


title: Day 3 control 1

description: rat lung, day3, ctrl


title: Test Sample CS-87_15ng

city: Ann Arbor

first: Rork

last: Kuick

state: MI

address: University of Michigan, SPH II, 1415 Washington Heights, Room M2533

country: USA

institute: University of Michigan

description: Test Sample CS-87_15ng

hyb_protocol: standard Affymetrix procedures

scan_protocol: standard Affymetrix procedures

data_processing: Ann Arbor quantile-normalized trimmed-mean method

organism: Homo sapiens

source_name: invasive squamous cell carcinoma of the cervix

label_protocol: 20-100 ng of total RNA was processed to produce biotinylated cRNA targets, using two rounds of T7-base RNA amplification with the Arcturus RiboAmp kit (KIT0201).

extract_protocol: Total RNA was extracted from 1000-5000 laser capture microdissected cells using the Arcturus PicoPure RNA isolation Kit (KIT0202).

tag: Test Sample


title: Test Sample C-2T-2-100ng

description: Test Sample C-2T-2-100ng

label_protocol: 100 ng of total RNA was processed to produce biotinylated cRNA targets, using two rounds of T7-base RNA amplification with the Arcturus RiboAmp kit (KIT0201).

extract_protocol: Total RNA was extracted from the tissue lysate using Trizol (Invitrogen) and cleanup performed with an RNeasy kit (Qiagen)


title: 1% Oxygen 16h

city: Toronto

first: Sara

last: Arab

state: ONT

address: 610 University Avenue

department: Cardiology

country: Canada

institute: Toronto General Hospital

description: standard affymetrix protocol using MAS5.0 algorithm from affymetrix

data_processing: arrays scaled to 150 intensity

treatment_protocol: HASMC cells exposed to hypoxia (1% O2 and 3% O2) for 16 or 48 hours, or normoxia

tag: Human aortic smooth muscle cells (HASMC)


title: 1% Oxygen 48h


title: Day 3 smoke exposure 1

description: rat lung, day3, smoke


title: Test Sample C-2T-1-Stand

description: Test Sample C-2T-1-Stand

label_protocol: 5 µg of total RNA was processed to produce biotinylated cRNA targets, using a single round of in vitro transcription.


title: 3% Oxygen 48h


title: Control for 3% Oxygen

source_name: 3% CT


title: 3% Oxygen 16h


title: 702

type: genomic

city: Birmingham

first: Jan

middle: P

last: Dumanski

state: AL

address: 720 20th Street South

department: Department of Genetics

institute: University of Alabama

description: Analysis of copy number variability in concordant healthy monozygotic twin pairs as well as three monozygostic twin pairs discordant a Parkinsons disease (PD) phenotype using the Illumina HumanHap 300 dead chips

hyb_protocol: According to the supplied Illumina HumanHap 300 protocol

data_processing: We focused on the heterozygous SNPs with allele frequencies 0.1< Allele freq <0.9. The absolute difference for between the twins in each pair was calculated for these SNPs and plotted using MS Excel

label: A-DNP and C-Bio

molecule: genomic DNA

source_name: Peripheral blood derived DNA from probable PD

extract_protocol: genomic DNA isolation with phenol extraction according to standard protocol (Sambrook, J., Fritsch, E. F. & Maniatis, T. Molecular cloning; a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1989)

tag: probable PD


title: Control for 1% Oxygen

hyb_protocol: standard affymetrix protocol

scan_protocol: standard affymetrix protocol

label: Biotin

source_name: 1% CT

label_protocol: standard affymetrix protocol

extract_protocol: Standard Trizol  protocol


title: 291

scan_protocol: According to the supplied Illumina HumanHap 300 protocol

source_name: Peripheral blood derived DNA from unaffected

tag: Unaffected


title: 711-4

description: Denoted  11.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 44 year old

label_protocol: According to the supplied Illumina HumanHap 300 protocol

tag: healthy concordant monozygotic twin, male, 44 years old at sampling


title: 794-3

description: Denoted  94.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 50 year old

tag: healthy concordant monozygotic twin, female, 50 years old at sampling


title: 492


title: 785-3

description: Denoted  85.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 60 year old

tag: healthy concordant monozygotic twin, female, 60 years old at sampling


title: 785-4

description: Denoted  85.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 292

source_name: Peripheral blood derived DNA from possible PD

tag: possible PD, Chronic lymphocytic leukemia


title: 722-3

description: Denoted  22.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 41 year old

tag: healthy concordant monozygotic twin, male, 41 years old at sampling


title: 711-3

description: Denoted  11.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 794-4

description: Denoted  94.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 783-4

description: Denoted  83.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 37 year old

tag: healthy concordant monozygotic twin, female, 37 years old at sampling


title: 722-4

description: Denoted  22.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 701


title: 771-3

description: Denoted  71.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

tag: healthy concordant monozygotic twin, female, 41 years old at sampling


title: 491


title: 771-4

description: Denoted  71.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 760-3

description: Denoted  D.7 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 752-4

description: Denoted  52.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 42 year old

tag: healthy concordant monozygotic twin, female, 42 years old at sampling


title: 752-3

description: Denoted  52.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 783-3

description: Denoted  83.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: 736-4

description: Denoted  36.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.

source_name: Peripheral blood derived DNA from healthy 45 year old

tag: healthy concordant monozygotic twin, female, 45 years old at sampling


title: DLA54 contrtle

status: Public on Dec 10 2007

city: Paris

first: Karine

last: Clement

address: place du parvis Notre-Dame

department: Service de Medecine et Nutrition

country: France

institute: Hotel-Dieu

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/48979.gif; format: GIF

data_processing: VALUE is Log (base 2) of the ratio of the median of Channel 2 (usually 635 nm) to Channel 1 (usually 532 nm)

source_name: 3 microgrammes amplified RNA from reference pool

source_name: 3 microgrammes amplified RNA from adipocytes


title: 760-4

description: Denoted  D.8 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: Colon-Saline-w10

city: Baltimore

first: Shukti

last: Chakravarti

state: MD

address: 720 Rutland Ave

department: Medicine

institute: Johns Hopkins University School of Medicine

description: Mice were sacrificed at 2 weeks (n=2) and 4 weeks (n=2) after six saline enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were prepared using the manufacturer’s standard  procedures from 10ug of total RNA pooled from 4 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0.

organism: Mus musculus

source_name: colon, saline treatment

value: CD-1 outbred.

value: female.

tag: Age

value: 10-12 weeks at the beginning of experiment.

value: colon.


title: Colon-TNBS-w8

description: Mice were sacrificed at 2 weeks after six TNBS in ethanol enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were prepared using the manufacturer’s standard procedures from 10ug of total RNA pooled from 4 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0.

source_name: colon, TNBS treatment

tag: Strain


title: DLA54 BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/48896.gif; format: GIF

tag: 3 microgrammes amplified RNA from reference pool

source_name: 3 microgrammes amplified RNA from adipocytes treated with BRL+RA


title: Colon-TNBS-w12

description: Mice were sacrificed at 6 weeks after six TNBS in ethanol enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were prepared using the manufacturer’s standard procedures from 10ug of total RNA pooled from 4 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0.

tag: Gender

tag: Tissue


title: Colon-TNBS-w10

description: Mice were sacrificed at 4 weeks after six TNBS in ethanol enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were prepared using the manufacturer’s standard procedures from 10ug of total RNA pooled from 5 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0.

source_name: colon, TNBS treament


title: Dental pulp fibroblasts treated with lipopolysaccharide_rep3

status: Public on Dec 07 2007

city: Lyon

first: Jean-Christophe

last: Farges

address: 11, G. Paradin Street

department: Faculty of Odontology

institute: University Lyon 1

description: Files were converted into numerical data using the ScanAlyze software (http://www.microarrays.org/software.html).

hyb_protocol: After pre-hybridization with GEAhyb Hybridization Solution (SuperArray) containing 100 g/ml denatured salmon sperm DNA (Sigma) for 4 h at 60°C, membranes were hybridized at 60°C for 15 h with radioactive probes (50-200 x 106 cpm each) previously denaturated at 95°C for 4 min. Membranes were washed twice with 2X SSC – 1% SDS for 15 min and twice with 0.1X SSC – 0.5% SDS for 15 min, then aligned on a PhosphorImaging screen (Molecular Dynamics, Amersham Biosciences, Orsay, France) and exposed for 72 h at room temperature. Reference: Durand et al., J Immunol 2006;176:2880.

scan_protocol: Array images were obtained by scanning the screen with a PhosphorImager (Molecular Dynamics).

data_processing: Numerical data were analyzed with the GEArray Analyzer software (http://www.superarray.com/). Hybridization signals were normalized for each gene to the PPIA (cyclophilin A) signals observed on the same membrane. Background was given by the mean value of the hybridization signals recorded for pUC18 plasmid.

source_name: Healthy human dental pulp from which explants were cultured for 4 weeks.

label_protocol: AmpoLabeling-LPR kit (SuperArray Bioscience Corp., Frederick, MD, USA)

growth_protocol: Cells were cultured as described (Couble et al., Calcif Tissue Int 2000;66:129) and stimulated with 1 µg/mL lipopolysaccharide (LPS) for 8 hours.

extract_protocol: Total RNA was extracted with the Nucleospin RNA II kit (Macherey-Nagel, Düren, Germany) according to the manufacturer’s instructions.

tag: Twenty healthy non-erupted human third molars were collected with informed consent of the patients, in accordance with the French Public Health Code and following a protocol approved by the local ethics committee.


title: Colon-saline-w6-2

description: Mice were sacrificed at 3 day after six saline enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were prepared using the manufacturer’s standard procedures from 10ug of total RNA pooled from 5 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0. Two replicates of colonic total RNA were analyzed.


title: DLA56 BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/48981.gif; format: GIF

tag: 3 microgrammes amplified RNA from adipocytes treated with BRL+RA


title: Colon saline-w6-1

description: Mice were sacrificed at 3 days after six saline enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were produced using the manufacturer’s standard procedures from 10ug of total RNA pooled from 5 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0. Two replicates of colonic total RNA were analyzed.


title: DLA56 contrtle

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/48980.gif; format: GIF

tag: 3 microgrammes amplified RNA from adipocytes


title: Dental pulp fibroblasts treated with lipopolysaccharide_rep1


title: Dental pulp fibroblasts treated with lipopolysaccharide_rep2


title: 761-4

description: Denoted  61.2 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: Dental pulp fibroblasts treated with poly(I:C)_rep3

growth_protocol: Cells were cultured as described (Couble et al., Calcif Tissue Int 2000;66:129) and stimulated with 25 µg/mL polyinosinedeoxycytidylic acid (poly[I:C]) for 8 hours.


title: DLA56 PGC1

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49050.gif; format: GIF

source_name: 3 microgrammes amplified RNA from adipocytes overexpressing PGC1


title: DLA57 controle

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49078.gif; format: GIF


title: Dental pulp fibroblasts treated with poly(I:C)_rep2


title: DLA54 PGC1+BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/48953.gif; format: GIF

source_name: 3 microgrammes amplified RNA from adipocytes overexpressing PGC1 and treated with BRL+RA


title: Dental pulp fibroblasts treated with poly(I:C)_rep1


title: DLA57 PGC1

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49074.gif; format: GIF

tag: 3 microgrammes amplified RNA from adipocytes overexpressing PGC1


title: Dental pulp fibroblasts_rep3

growth_protocol: Cells were cultured as described (Couble et al., Calcif Tissue Int 2000;66:129).


title: Dental pulp fibroblasts treated with lipoteichoic acid_rep2

growth_protocol: Cells were cultured as described (Couble et al., Calcif Tissue Int 2000;66:129) and stimulated with 1 µg/mL lipoteichoic acid (LTA) for 8 hours.


title: DLA57 PGC1+BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49076.gif; format: GIF

tag: 3 microgrammes amplified RNA from adipocytes overexpressing PGC1 and treated with BRL+RA


title: DLA60a contrtle

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49077.gif; format: GIF


title: 736-3

description: Denoted  36.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: Dental pulp fibroblasts_rep2


title: DLA57 BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49075.gif; format: GIF


title: Dental pulp fibroblasts treated with lipoteichoic acid_rep3


title: DLA60a BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49079.gif; format: GIF


title: Dental pulp fibroblasts treated with lipoteichoic acid_rep1


title: DLA54 PGC1

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/48897.gif; format: GIF


title: DLA60a PGC1

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49080.gif; format: GIF

hyb_protocol: After denaturation, the probes were added to the array in a 3.4 X SSC 0.3% SDS buffer which was covered by a glass coverslip. The slide was then placed in a sealed humidified hybridization chamber for 16 h hybridization at 65°C. Slides were washed twice in 2 X SSC 0.1% SDS, 1 X SSC then, 0.5 X SSC. The arrays were immediately scanned using a GenePix 4000A scanner (Axon Instruments). Images were analyzed using GenePix pro 3 software.

label_protocol: Amplified RNA (aRNA) were prepared using the Message Amp aRNA Kit (Ambion, Cambridgeshire, UK). Briefly, 400 ng of total RNA were used for an RT reaction containing a T7 promoter sequence primer. After second strand cDNA synthesis, in vitro transcription was performed overnight resulting in an approximately 1000 fold yield in aRNA. aRNA quantity and quality were assessed using the Agilent 2100 bioanalyzer.Fluorescent probes were synthesized from 3 µg of aRNA using the CyScribe First Strand cDNA Labelling Kit (Amersham Biosciences, Orsay, France). Cy3 probe from one subject was purified and concentrated using Microcon YM-30 column (Millipore) after the addition of human cot-1 DNA (Invitrogen), yeast t RNA and poly(dA)DNA (Sigma).

extract_protocol: Total RNA was extracted using the RNA STAT-60 isolation reagent (Tel-Test). Total RNA quantity and quality were assessed using the Agilent 2100 bioanalyzer and RNA 6000 labChip Kit (Agilent Technologies, Massy, France).

label_protocol:
Amplified RNA (aRNA) were prepared using the Message Amp aRNA Kit (Ambion, Cambridgeshire, UK). Briefly, 400 ng of total RNA were used for an RT reaction containing a T7 promoter sequence primer. After second strand cDNA synthesis, in vitro transcription was performed overnight resulting in an approximately 1000 fold yield in aRNA. aRNA quantity and quality were assessed using the Agilent 2100 bioanalyzer.
Fluorescent probes were synthesized from 3 µg of aRNA using the CyScribe First Strand cDNA Labelling Kit (Amersham Biosciences, Orsay, France). Cy5 probe from one subject waspurified and concentrated using Microcon YM-30 column (Millipore) after the addition of human cot-1 DNA (Invitrogen), yeast t RNA and poly(dA)DNA (Sigma).


title: Odontoblast-like cells treated with lipopolysaccharide_rep2

description: Files were converted into numerical data using the ScanAlyze software (http://www.microarrays.org/software.html).

source_name: Healthy human dental pulp from which explants were cultured for 4 weeks to obtain odontoblast-like cell differentiation.


title: Odontoblast-like cells treated with lipopolysaccharide_rep1


title: Odontoblast-like cells treated with lipopolysaccharide_rep3


title: Dental pulp fibroblasts_rep1


title: DLA60a PGC1+BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49406.gif; format: GIF


title: Odontoblast-like cells treated with poly(I:C)_rep1


title: Odontoblast-like cells treated with poly(I:C)_rep2


title: Odontoblast-like cells treated with lipoteichoic acid_rep3


title: Odontoblast-like cells treated with poly(I:C)_rep3


title: Odontoblast-like cells treated with lipoteichoic acid_rep1


title: Odontoblast-like cells treated with lipoteichoic acid_rep2


title: Odontoblast-like cells_rep3

source_name: Healthy human dental pulp from which explants were cultured for 4 weeks to obtain odontoblast-like cell differentiation


title: 761-3

description: Denoted  61.1 in Online Only Table 1 in the manuscript called Phenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles by CE Bruder et. al.


title: Odontoblast-like cells_rep1

source_name: Healthy human dental pulps from which explants were cultured for 4 weeks to obtain odontoblast-like cell differentiation.


title: DLA56 PGC1+BRL+RA

description:
Simple annotation: Primary human tissue, obesity
Image: http://smd.stanford.edu/MicroArray/gifs/2004-02/49073.gif; format: GIF


title: Colon-TNBS-w6

description: Mice were sacrificed at 3 days after six TNBS in ethanol enemas. Colon tissue samples were collected at 4 ± 0.5 cm from the anus. Total RNA was extracted using TRIzol reagent. cRNA targets were prepared using the manufacturer’s standard procedures from 10ug of total RNA pooled from 6 mice. The expression values of all probe sets were scaled to 150 of Target Intensity by using Affymetrix Microarray Suite 5.0.


title: Odontoblast-like cells_rep2


title: MPR007454

status: Public on Dec 06 2007

city: Cambridge

first: George

last: Mulligan

state: MA

address: 35 Landsdowne Stree

department: Clinical Development

institute: Millennium Pharmaceuticals

description: Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

hyb_protocol: cRNA for each sample was hybridized in triplicate to the U133A/B array.  Data represent median of replicates that passed array QC.

scan_protocol: Microarrays were scanned with GeneArray 3000 scaner (Affymetrix).

data_processing: Dataprocessing used Affymetrix MAS5.0.

source_name: tumor sample

label_protocol: A standard T7 based amplification protocol (Affymetrix) was used to convert 2.0 microgram of RNA to biotinylated cRNA.

growth_protocol: tumor samples were collected during patient screening period prior to entry into clinical trials for the treatment of multiple myeloma

extract_protocol: Total RNA was isolated  using Qiagen RNAeasy kit

treatment_protocol: samples were subject to a rapid enrichment procedure (see details in http://bloodjournal.hematologylibrary.org/cgi/content/full/109/8/3177) and tumor cell pellet was frozen

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 69

tag: Date_of_Randomization = 21-May-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 42

tag: Days_Survived_From_Randomization = 799

tag: albumin = 35

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 18.49

tag: TC_Class_2006 = MAF


title: MPR008045

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 11-Nov-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PD

tag: PGx_Days_To_Progression = 84

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 404

tag: albumin = 38

tag: C_Reactive_Protein = 5.5

tag: Beta2_Microglobulin = 10.6

tag: Number_of_Prior_Lines = 6

tag: meanMyelScore = 28.29


title: MPR007446

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 29-Aug-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 305

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 691

tag: albumin = 27

tag: Beta2_Microglobulin = 4.5

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 35.49

tag: TC_Class_2006 = D2


title: MPR007614

tag: studyCode = 39

tag: sex = Female

tag: Age_at_Randomization = 51

tag: Date_of_Randomization = 16-Jul-03

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 215

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 685

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 1.8

tag: meanMyelScore = 45.37

tag: TC_Class_2006 = D1


title: MPR007453

tag: treatment = PS341

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 30-May-03

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 109

tag: PGx_CensorReason = Alternative therapy

tag: Days_Survived_From_Randomization = 620

tag: albumin = 31

tag: C_Reactive_Protein = 19

tag: Beta2_Microglobulin = 3

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 55.08


title: MPR007450

tag: studyCode = 39

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 31-Mar-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 14

tag: Days_Survived_From_Randomization = 842

tag: albumin = 35

tag: C_Reactive_Protein = 4.3

tag: Beta2_Microglobulin = 4.8

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 32.28


title: MPR007451

tag: treatment = PS341

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 28-Jul-03

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 71

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 190

tag: albumin = 24

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 5.4

tag: meanMyelScore = 31.37


title: MPR007462

tag: studyCode = 39

tag: race = White

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 24-Mar-03

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 88

tag: Days_Survived_From_Randomization = 667

tag: albumin = 41

tag: C_Reactive_Protein = 4.6

tag: Beta2_Microglobulin = 3.1

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 35.01

tag: TC_Class_2006 = D1


title: MPR007449

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 17-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 170

tag: Days_Survived_From_Randomization = 660

tag: albumin = 43

tag: Beta2_Microglobulin = 2.4

tag: meanMyelScore = 37.44


title: MPR007440

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 26-Aug-03

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 472

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 680

tag: albumin = 34

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 7

tag: meanMyelScore = 48.93

tag: Mayo_Clinic_ProliferativeIndex = 0.75

tag: TC_Class_2006 = D2


title: MPR007447

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 28-Apr-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 36

tag: Days_Survived_From_Randomization = 816

tag: albumin = 48

tag: Beta2_Microglobulin = 4.8

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 32.29

tag: TC_Class_2006 = D3


title: MPR007445

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 72

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 84

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 165

tag: albumin = 38

tag: C_Reactive_Protein = 27.4

tag: Beta2_Microglobulin = 1.9

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 30.08


title: MPR007439

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 19-May-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 43

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 69

tag: albumin = 35

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 21.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 77.73


title: MPR007438

tag: race = White

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 13-Jun-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 136

tag: Days_Survived_From_Randomization = 554

tag: albumin = 41

tag: Beta2_Microglobulin = 2.2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 14.69

tag: TC_Class_2006 = D1


title: MPR007431

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 28-Apr-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 127

tag: Days_Survived_From_Randomization = 275

tag: albumin = 47

tag: C_Reactive_Protein = 7.9

tag: Beta2_Microglobulin = 15.6

tag: meanMyelScore = 32.81


title: MPR007433

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 69

tag: Date_of_Randomization = 4-Aug-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 21

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 64

tag: albumin = 38

tag: C_Reactive_Protein = 61.4

tag: Beta2_Microglobulin = 5.5

tag: meanMyelScore = 52.35

tag: TC_Class_2006 = D2


title: MPR007444

tag: studyCode = 39

tag: sex = Male

tag: Age_at_Randomization = 39

tag: Date_of_Randomization = 1-Aug-03

tag: PGx_Response = NC

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 87

tag: Days_Survived_From_Randomization = 247

tag: albumin = 44

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.2

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 9.04

tag: TC_Class_2006 = MAF


title: MPR007437

tag: treatment = Dex

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 5-Jun-03

tag: Myeloma_Measure = IGA

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 109

tag: Days_Survived_From_Randomization = 543

tag: albumin = 41

tag: Beta2_Microglobulin = 2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 16.94


title: MPR007434

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 1-Sep-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 193

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 613

tag: albumin = 39

tag: C_Reactive_Protein = 9

tag: Beta2_Microglobulin = 16.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 41.71

tag: TC_Class_2006 = D2


title: MPR006928

tag: studyCode = 39

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 5-Nov-02

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Days_To_Progression = 94

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 283

tag: C_Reactive_Protein = 8.9

tag: Beta2_Microglobulin = 6

tag: meanMyelScore = 31.19

tag: Mayo_Clinic_ProliferativeIndex = 0.81


title: MPR006905

tag: treatment = PS341

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 13-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 164

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.6

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 30.37

tag: Mayo_Clinic_ProliferativeIndex = 3.96


title: sua5D 1st-2

status: Public on Oct 01 2008

city: shanghai

first: feilong

last: meng

address: 320 yuyang road

department: SIBCB

country: China

institute: Shanghai institutes for biology sciences

description: performed following Affymetrix standard protocols

hyb_protocol: Hybridization Control Kit Affymetrix

scan_protocol: Gene array Scanner3000 Affymetrix

data_processing: GCOS1.2 Affymetrix

organism: Saccharomyces cerevisiae

source_name: sua5D 35generation after sporulation

label_protocol: IVT Labeling Kit  Affymetrix

growth_protocol:
innoculate in 5ml YPD liquid medium
harvest at mid-log phase

extract_protocol: the RNeasy Mini Kit (Qiagen) and on-column DNase Digestion Kit (Qiagen)

tag: background

value: dissection sproe of BY4743 MAT a

tag: restreak on YPD plate once, innoculate in 5ml YPD liquid medium

tag: harvest at mid-log phase


title: MPR007432

tag: studyCode = 39

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 19-May-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 22

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 692

tag: albumin = 41

tag: C_Reactive_Protein = 5

tag: Beta2_Microglobulin = 3.6

tag: meanMyelScore = 22.38


title: MPR006882

tag: treatment = PS341

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 7-Oct-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 75

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 667

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 22.93


title: MPR006901

tag: studyCode = 39

tag: sex = Male

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 42

tag: Date_of_Randomization = 6-Jun-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 328

tag: Days_Survived_From_Randomization = 756

tag: albumin = 42

tag: Beta2_Microglobulin = 2.9

tag: meanMyelScore = 23.69

tag: TC_Class_2006 = D2


title: MPR006858

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 11-Apr-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 314

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 790

tag: albumin = 35

tag: Beta2_Microglobulin = 4.5

tag: meanMyelScore = 19.82

tag: TC_Class_2006 = D1


title: MPR006854

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 27-May-03

tag: PGx_Days_To_Progression = 104

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 723

tag: albumin = 41

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 1.9

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 13.04


title: MPR007344

tag: treatment = Dex

tag: race = Black

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 3-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 40

tag: Days_Survived_From_Randomization = 227

tag: albumin = 29

tag: C_Reactive_Protein = 4.3

tag: Beta2_Microglobulin = 5.9

tag: meanMyelScore = 29.14

tag: TC_Class_2006 = D2


title: MPR006875

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 12-Apr-03

tag: PGx_Response = NC

tag: PGx_Days_To_Progression = 91

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = MELPHALAN

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 522

tag: albumin = 36

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 7.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 42.97

tag: TC_Class_2006 = D1


title: MPR006853

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 44

tag: Date_of_Randomization = 6-Jun-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 119

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 762

tag: albumin = 48

tag: Beta2_Microglobulin = 2.7

tag: meanMyelScore = 21.38


title: MPR006852

tag: race = White

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 11-Aug-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 147

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 353

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 26.93


title: MPR006850

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 27-Feb-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = ?

tag: Days_Survived_From_Randomization = 748

tag: albumin = 48

tag: Beta2_Microglobulin = 2.2

tag: meanMyelScore = 35.67

tag: Mayo_Clinic_ProliferativeIndex = 0.91

tag: TC_Class_2006 = D2


title: MPR006849

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 14-Feb-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 31

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 351

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 6.6

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 46.94

tag: TC_Class_2006 = None


title: MPR006848

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 76

tag: Date_of_Randomization = 4-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Days_To_Progression = 102

tag: PGx_CensorReason = No more data

tag: PGx_Alternative_Therapy = did get VELCADE 2 months later(9/15

tag: Days_Survived_From_Randomization = 565

tag: albumin = 29

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 18.2

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 27.2


title: MPR006846

tag: race = White

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 6-Feb-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 165

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 373

tag: albumin = 42

tag: C_Reactive_Protein = 4.2

tag: Beta2_Microglobulin = 2.9

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 18.17


title: MPR006845

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 10-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 148

tag: Days_Survived_From_Randomization = 844

tag: albumin = 46

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 67.3

tag: TC_Class_2006 = D1


title: MPR006844

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 83

tag: Date_of_Randomization = 27-Feb-03

tag: PGx_Days_To_Progression = 43

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = ?

tag: Days_Survived_From_Randomization = 886

tag: albumin = 32

tag: C_Reactive_Protein = 4.1

tag: Beta2_Microglobulin = 11.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 22.27


title: MPR006841

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 17-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 188

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 425

tag: C_Reactive_Protein = 79.7

tag: Beta2_Microglobulin = 6.1

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 40.22


title: MPR006842

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 38

tag: Date_of_Randomization = 4-Feb-03

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = VELCADE & DECADRON

tag: Days_Survived_From_Randomization = 682

tag: albumin = 46

tag: C_Reactive_Protein = 5.2

tag: Beta2_Microglobulin = 1.9

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 12.47

tag: Mayo_Clinic_ProliferativeIndex = 1.65

tag: TC_Class_2006 = D1


title: MPR006843

tag: sex = Female

tag: race = Black

tag: Age_at_Randomization = 57

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 400

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 843

tag: albumin = 35

tag: C_Reactive_Protein = 18.6

tag: Beta2_Microglobulin = 2.9

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 23.69

tag: TC_Class_2006 = D2


title: MPR006838

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 84

tag: Date_of_Randomization = 3-Dec-02

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 314

tag: Days_Survived_From_Randomization = 913

tag: albumin = 27

tag: C_Reactive_Protein = 4.7

tag: Beta2_Microglobulin = 15.1

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 10.78


title: MPR006840

tag: treatment = Dex

tag: sex = Female

tag: race = Black

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 17-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 297

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 852

tag: albumin = 33

tag: C_Reactive_Protein = 23.7

tag: Beta2_Microglobulin = 1.6

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 17.04

tag: TC_Class_2006 = D3


title: MPR006836

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 50

tag: Date_of_Randomization = 21-Nov-02

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 64

tag: Days_Survived_From_Randomization = 903

tag: albumin = 34

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.1

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 9.73

tag: TC_Class_2006 = D1


title: MPR006837

tag: studyCode = 39

tag: race = Black

tag: Age_at_Randomization = 33

tag: Date_of_Randomization = 25-Nov-02

tag: Myeloma_Measure = IGA

tag: PGx_Days_To_Progression = 46

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 285

tag: albumin = 31

tag: C_Reactive_Protein = 4.3

tag: Beta2_Microglobulin = 2.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 17.62


title: MPR006832

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 2-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 145

tag: Days_Survived_From_Randomization = 917

tag: albumin = 29

tag: C_Reactive_Protein = 4.1

tag: Beta2_Microglobulin = 7.6

tag: meanMyelScore = 26.02

tag: TC_Class_2006 = MAF


title: MPR006831

tag: studyCode = 39

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 15-Aug-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = MR

tag: PGx_Days_To_Progression = 94

tag: Days_Survived_From_Randomization = 480

tag: albumin = 45

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 38.59

tag: TC_Class_2006 = D1


title: MPR006824

tag: sex = Female

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 9-Jun-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 77

tag: PGx_CensorReason = No more data

tag: PGx_Alternative_Therapy = did get VELCADE 35 days later

tag: Days_Survived_From_Randomization = 764

tag: albumin = 41

tag: Beta2_Microglobulin = 2.5

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 44.79

tag: TC_Class_2006 = D3


title: MPR006822

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 49

tag: Date_of_Randomization = 22-Apr-03

tag: Myeloma_Measure = IGA

tag: PGx_Days_To_Progression = 20

tag: Days_Survived_From_Randomization = 697

tag: albumin = 34

tag: C_Reactive_Protein = 4.5

tag: meanMyelScore = 18.48


title: MPR006875

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 12-Apr-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 91

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = MELPHALAN

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 522

tag: albumin = 36

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 7.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 42.97

tag: TC_Class_2006 = D1


title: MPR006818

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 1-Apr-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 307

tag: albumin = 40

tag: Beta2_Microglobulin = 3.2

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 33.78

tag: Mayo_Clinic_ProliferativeIndex = 1.68

tag: TC_Class_2006 = D2


title: MPR006810

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 37

tag: Date_of_Randomization = 23-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 105

tag: Days_Survived_From_Randomization = 1017

tag: albumin = 33

tag: C_Reactive_Protein = 175.2

tag: Beta2_Microglobulin = 5.2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 24.18


title: MPR006811

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 30-Sep-02

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 189

tag: Days_Survived_From_Randomization = 1061

tag: albumin = 37

tag: C_Reactive_Protein = 154.2

tag: Beta2_Microglobulin = 2.8

tag: meanMyelScore = 29.28

tag: TC_Class_2006 = D1


title: MPR006799

tag: studyCode = 39

tag: sex = Male

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 5-May-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 185

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 611

tag: albumin = 31

tag: C_Reactive_Protein = 7.12

tag: Beta2_Microglobulin = 4.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 14.82


title: MPR006806

tag: studyCode = 39

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 3-Jul-03

tag: PGx_Days_To_Progression = 439

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 719

tag: albumin = 33

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 12.5

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 53.88

tag: TC_Class_2006 = MAF


title: MPR006797

tag: treatment = Dex

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 20-May-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 175

tag: albumin = 37

tag: C_Reactive_Protein = 16.3

tag: Beta2_Microglobulin = 5.1

tag: meanMyelScore = 33.19

tag: Mayo_Clinic_ProliferativeIndex = 0.67

tag: TC_Class_2006 = D1


title: MPR006808

tag: studyCode = 39

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 3-Sep-02

tag: Myeloma_Measure = IGG

tag: Days_Survived_From_Randomization = 974

tag: albumin = 33

tag: C_Reactive_Protein = 5.9

tag: Beta2_Microglobulin = 4.6

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 9.56


title: MPR006798

tag: treatment = Dex

tag: Age_at_Randomization = 46

tag: Date_of_Randomization = 21-Apr-03

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 63

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 541

tag: albumin = 44

tag: C_Reactive_Protein = 8.73

tag: Beta2_Microglobulin = 5

tag: meanMyelScore = 28.33


title: MPR006777

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 6-Oct-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = CR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 366

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 443

tag: albumin = 40

tag: C_Reactive_Protein = 96.1

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 24.29


title: MPR006776

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 28-Sep-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 24

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 79

tag: albumin = 47

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 5.1

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 21.99

tag: TC_Class_2006 = D2


title: MPR006792

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 77

tag: Date_of_Randomization = 25-Jun-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 65

tag: Days_Survived_From_Randomization = 247

tag: albumin = 44

tag: Beta2_Microglobulin = 3.7

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 44.46

tag: TC_Class_2006 = MAF


title: MPR006789

tag: studyCode = 39

tag: Age_at_Randomization = 71

tag: Date_of_Randomization = 27-May-03

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 84

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 366

tag: albumin = 45

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 4.5

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 35.35


title: MPR006780

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 19-May-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 231

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 597

tag: albumin = 44

tag: Beta2_Microglobulin = 2.9

tag: meanMyelScore = 21.18

tag: TC_Class_2006 = D2


title: MPR006770

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 8-Dec-02

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 78

tag: Days_Survived_From_Randomization = 577

tag: albumin = 39

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.9

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 26.64

tag: TC_Class_2006 = MAF


title: MPR006767

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 51

tag: Date_of_Randomization = 18-Aug-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 294

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 700

tag: albumin = 50

tag: Beta2_Microglobulin = 2.1

tag: meanMyelScore = 13.65

tag: TC_Class_2006 = D1


title: MPR006768

tag: studyCode = 39

tag: Age_at_Randomization = 44

tag: Date_of_Randomization = 6-Oct-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 21

tag: Days_Survived_From_Randomization = 661

tag: albumin = 39

tag: C_Reactive_Protein = 4

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 30


title: MPR006756

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 80

tag: Date_of_Randomization = 22-Sep-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 570

tag: albumin = 24

tag: C_Reactive_Protein = 14

tag: Beta2_Microglobulin = 42

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 69.72

tag: Mayo_Clinic_ProliferativeIndex = 0.54

tag: TC_Class_2006 = MAF


title: MPR006763

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 11-Jun-03

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 170

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 756

tag: albumin = 36

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 14.08

tag: TC_Class_2006 = D2


title: MPR006757

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 49

tag: Date_of_Randomization = 13-Oct-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 30

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 66

tag: albumin = 48

tag: C_Reactive_Protein = 17.1

tag: Beta2_Microglobulin = 3

tag: meanMyelScore = 49.28


title: MPR006754

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 51

tag: Date_of_Randomization = 14-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 38

tag: Days_Survived_From_Randomization = 900

tag: albumin = 41

tag: C_Reactive_Protein = 4.1

tag: Beta2_Microglobulin = 1.3

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 11.24

tag: TC_Class_2006 = D1


title: MPR006743

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 80

tag: Date_of_Randomization = 5-Jun-03

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 417

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.7

tag: meanMyelScore = 32.03

tag: Mayo_Clinic_ProliferativeIndex = 0.95


title: MPR006742

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 71

tag: Date_of_Randomization = 12-May-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 71

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 111

tag: albumin = 35

tag: Beta2_Microglobulin = 5.9

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 14.92

tag: TC_Class_2006 = None


title: MPR006762

tag: treatment = Dex

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 5-Jun-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 106

tag: Days_Survived_From_Randomization = 503

tag: albumin = 33

tag: Beta2_Microglobulin = 6.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 36.79


title: MPR006733

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 17-Sep-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 47

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 92

tag: albumin = 37

tag: C_Reactive_Protein = 24

tag: Beta2_Microglobulin = 10.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 40.77


title: MPR006741

tag: studyCode = 39

tag: race = White

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 9-Apr-03

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 65

tag: Days_Survived_From_Randomization = 467

tag: albumin = 38

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 36.77


title: MPR006730

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 1-Aug-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 87

tag: Days_Survived_From_Randomization = 413

tag: albumin = 43

tag: Beta2_Microglobulin = 3.2

tag: meanMyelScore = 10.5

tag: TC_Class_2006 = D1


title: MPR006734

tag: studyCode = 39

tag: race = White

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 13-Oct-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Days_To_Progression = 84

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 147

tag: albumin = 40

tag: C_Reactive_Protein = 8.7

tag: Beta2_Microglobulin = 2.5

tag: meanMyelScore = 17.39

tag: TC_Class_2006 = D2


title: MPR006729

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 16-Jul-03

tag: Myeloma_Measure = IGA

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: Days_Survived_From_Randomization = 279

tag: albumin = 34

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.8

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 32.2

tag: TC_Class_2006 = MAF


title: MPR006724

tag: studyCode = 39

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 30-May-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 76

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 330

tag: albumin = 32

tag: C_Reactive_Protein = 29.1

tag: Beta2_Microglobulin = 7.4

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 42.3

tag: TC_Class_2006 = D1


title: MPR006717

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 30-Sep-03

tag: Myeloma_Measure = IGA

tag: PGx_Days_To_Progression = 34

tag: Days_Survived_From_Randomization = 289

tag: albumin = 27

tag: C_Reactive_Protein = 150

tag: Beta2_Microglobulin = 6.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 13.47

tag: TC_Class_2006 = D2


title: MPR006710

tag: race = White

tag: Age_at_Randomization = 58

tag: Date_of_Randomization = 6-Oct-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 70

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 570

tag: albumin = 46

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 4.5

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 18.5

tag: Mayo_Clinic_ProliferativeIndex = 1.18


title: MPR006718

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 56

tag: PGx_Response = PR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 154

tag: Days_Survived_From_Randomization = 612

tag: albumin = 51

tag: Beta2_Microglobulin = 3.6

tag: meanMyelScore = 15.76


title: MPR006702

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 7-Aug-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 53

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 291

tag: albumin = 29

tag: Beta2_Microglobulin = 8.6

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 32.47

tag: TC_Class_2006 = D1


title: MPR006705

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 66

tag: Date_of_Randomization = 8-Sep-03

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 171

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 276

tag: albumin = 39

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 6.7

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 30.6

tag: TC_Class_2006 = D2


title: MPR006709

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 16-Sep-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 168

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 215

tag: albumin = 46

tag: Beta2_Microglobulin = 2.5

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 26.32

tag: TC_Class_2006 = D1


title: MPR006701

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Date_of_Randomization = 29-Jul-03

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 195

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 672

tag: albumin = 38

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.6

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 22.37


title: MPR006684

tag: treatment = Dex

tag: sex = Male

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 6-Oct-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 72

tag: Days_Survived_From_Randomization = 212

tag: albumin = 40

tag: Beta2_Microglobulin = 3.2

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 36.33

tag: TC_Class_2006 = D2


title: MPR006696

tag: studyCode = 39

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 2-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 344

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 956

tag: albumin = 43

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.7

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 18.69

tag: TC_Class_2006 = D1


title: MPR006672

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 17-Jun-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 43

tag: Days_Survived_From_Randomization = 99

tag: albumin = 24

tag: C_Reactive_Protein = 100

tag: Beta2_Microglobulin = 14.5

tag: meanMyelScore = 36.5

tag: TC_Class_2006 = D2


title: MPR006670

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 6-May-03

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 58

tag: albumin = 33

tag: C_Reactive_Protein = 6.4

tag: Beta2_Microglobulin = 7.2

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 34.38

tag: TC_Class_2006 = MAF


title: MPR006679

tag: studyCode = 39

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 21-Jul-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 231

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 366

tag: albumin = 43

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.9

tag: meanMyelScore = 34.12


title: MPR006673

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 16-Jul-03

tag: PGx_Response = PR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 196

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 312

tag: albumin = 44

tag: Beta2_Microglobulin = 6.9

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 45.02


title: MPR006662

tag: studyCode = 39

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 14-Apr-03

tag: Myeloma_Measure = IGG

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 191

tag: Days_Survived_From_Randomization = 471

tag: albumin = 29

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 6.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 46.91


title: MPR006665

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 23-Jun-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 42

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 477

tag: albumin = 41

tag: Beta2_Microglobulin = 2.5

tag: meanMyelScore = 30.1

tag: TC_Class_2006 = D2


title: MPR006658

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 20-Jan-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 106

tag: Days_Survived_From_Randomization = 505

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.3

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 43.5

tag: TC_Class_2006 = D1


title: MPR006660

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 71

tag: Date_of_Randomization = 24-Mar-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 235

tag: Days_Survived_From_Randomization = 779

tag: albumin = 35

tag: C_Reactive_Protein = 8.1

tag: Beta2_Microglobulin = 6.2

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 41.31


title: MPR006641

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 18-Jul-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PD

tag: PGx_Days_To_Progression = 74

tag: Days_Survived_From_Randomization = 588

tag: albumin = 43

tag: Beta2_Microglobulin = 7

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 35.35


title: MPR006650

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 19-May-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 127

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 454

tag: albumin = 37

tag: C_Reactive_Protein = 18.7

tag: Beta2_Microglobulin = 6.7

tag: meanMyelScore = 42.66

tag: TC_Class_2006 = D2


title: MPR006634

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 81

tag: Date_of_Randomization = 22-Aug-03

tag: Myeloma_Measure = IGA

tag: PGx_Days_To_Progression = 67

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 94

tag: albumin = 26.7

tag: C_Reactive_Protein = 133.5

tag: Beta2_Microglobulin = 10.3

tag: Number_of_Prior_Lines = 2


title: MPR006626

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 25-Aug-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 37

tag: Days_Survived_From_Randomization = 112

tag: albumin = 38

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.1

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 34.75


title: MPR006627

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 55

tag: Myeloma_Measure = IGG

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: Days_Survived_From_Randomization = 336

tag: albumin = 37

tag: Beta2_Microglobulin = 10.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 16.78

tag: Mayo_Clinic_ProliferativeIndex = 1

tag: TC_Class_2006 = D1


title: MPR006619

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 26-May-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 232

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 730

tag: albumin = 51

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 4.2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 31.56


title: MPR006593

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 27

tag: Date_of_Randomization = 3-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 52

tag: Days_Survived_From_Randomization = 577

tag: albumin = 47

tag: Beta2_Microglobulin = 1.7

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 13.52

tag: TC_Class_2006 = D1


title: MPR006576

tag: race = White

tag: Age_at_Randomization = 47

tag: Date_of_Randomization = 13-Sep-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 551

tag: albumin = 43

tag: C_Reactive_Protein = 4.4

tag: Beta2_Microglobulin = 5.1

tag: meanMyelScore = 25.86

tag: Mayo_Clinic_ProliferativeIndex = 0.82


title: MPM002598

tag: studyCode = 24

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 13-Nov-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 75

tag: PGx_Alternative_Therapy = Dexamethasone

tag: Days_Survived_From_Randomization = 869

tag: C_Reactive_Protein = 1.6

tag: Beta2_Microglobulin = 38

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 56.14


title: MPM002600

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 6-Nov-01

tag: Myeloma_Measure = IGA

tag: PGx_Days_To_Progression = 42

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 234

tag: C_Reactive_Protein = 6

tag: Beta2_Microglobulin = 3.9

tag: meanMyelScore = 37.78

tag: TC_Class_2006 = MAF


title: MPM002618

tag: studyCode = 25

tag: treatment = PS341

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 22-Oct-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Days_To_Progression = 37

tag: Days_Survived_From_Randomization = 228

tag: albumin = 38

tag: C_Reactive_Protein = 40

tag: Beta2_Microglobulin = 3.5

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 35.89

tag: Mayo_Clinic_ProliferativeIndex = 2.2

tag: TC_Class_2006 = D3


title: MPM002596

tag: studyCode = 24

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 72

tag: Date_of_Randomization = 18-Dec-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 175

tag: PGx_CensorReason = entered 029

tag: Days_Survived_From_Randomization = 580

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 31

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 55.79

tag: TC_Class_2006 = D1


title: MPM002595

tag: treatment = PS341

tag: Age_at_Randomization = 43

tag: Date_of_Randomization = 6-Nov-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PD

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 42

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 480

tag: C_Reactive_Protein = 5

tag: Beta2_Microglobulin = 29

tag: meanMyelScore = 41.09


title: MPM002622

tag: studyCode = 25

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 18-Oct-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Days_To_Progression = 8

tag: Days_Survived_From_Randomization = 54

tag: albumin = 23

tag: C_Reactive_Protein = 64

tag: Beta2_Microglobulin = 1.03

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 30.83

tag: Mayo_Clinic_ProliferativeIndex = 1.76


title: MPM002593

tag: studyCode = 24

tag: treatment = PS341

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 7-Aug-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 62

tag: PGx_Alternative_Therapy = Dexamethasone

tag: Days_Survived_From_Randomization = 981

tag: C_Reactive_Protein = 9

tag: Beta2_Microglobulin = 55

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 42.55

tag: TC_Class_2006 = D1


title: MPM002592

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 6-Aug-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 363

tag: PGx_CensorReason = last follow up

tag: Days_Survived_From_Randomization = 878

tag: Beta2_Microglobulin = 0.33

tag: meanMyelScore = 36.68


title: MPM002585

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 48

tag: Date_of_Randomization = 2-Jul-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 21

tag: PGx_CensorReason = Dex at 21 days

tag: PGx_Alternative_Therapy = Dex at 21 days

tag: Days_Survived_From_Randomization = 262

tag: albumin = 35

tag: C_Reactive_Protein = 20

tag: Beta2_Microglobulin = 1.9

tag: Number_of_Prior_Lines = 7

tag: meanMyelScore = 49.59


title: MPM002583

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: race = Other

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 11-Sep-01

tag: Myeloma_Measure = UNK

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = unclear but no screen data and IRC

tag: PGx_Alternative_Therapy = unclear but no screen data and IRC

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 304

tag: albumin = 32

tag: C_Reactive_Protein = 1

tag: Beta2_Microglobulin = 9.5

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 35

tag: Mayo_Clinic_ProliferativeIndex = 0.77

tag: TC_Class_2006 = MAF


title: MPM002594

tag: studyCode = 24

tag: treatment = PS341

tag: sex = Female

tag: race = Black

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 13-Aug-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 119

tag: Days_Survived_From_Randomization = 641

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 80

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 47.07


title: MPM002586

tag: studyCode = 25

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 48

tag: Date_of_Randomization = 23-Oct-01

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Days_To_Progression = 41

tag: PGx_CensorReason = Dex at 41 days

tag: PGx_Alternative_Therapy = Dex at 41 days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 524

tag: albumin = 28

tag: C_Reactive_Protein = 3.1

tag: Beta2_Microglobulin = 4.8

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 32.49

tag: Mayo_Clinic_ProliferativeIndex = 0.5


title: MPM002581

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 34

tag: Date_of_Randomization = 6-Aug-01

tag: Myeloma_Measure = UNK

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_CensorReason = no follow up

tag: PGx_Alternative_Therapy = no follow up

tag: Days_Survived_From_Randomization = 91

tag: albumin = 36

tag: C_Reactive_Protein = 103.1

tag: Beta2_Microglobulin = 6.8

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 46.67


title: MPM002576

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 2-Nov-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 129

tag: PGx_CensorReason = Dex at 129days

tag: PGx_Alternative_Therapy = Dex at 129days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 734

tag: albumin = 26

tag: C_Reactive_Protein = 36

tag: Beta2_Microglobulin = 1.48

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 25.87


title: MPM002582

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 51

tag: Date_of_Randomization = 13-Mar-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 82

tag: PGx_CensorReason = Dex at 82 days

tag: PGx_Alternative_Therapy = Dex at 82 days

tag: Days_Survived_From_Randomization = 360

tag: albumin = 37

tag: C_Reactive_Protein = 2.8

tag: Beta2_Microglobulin = 3.2

tag: Number_of_Prior_Lines = 9

tag: meanMyelScore = 60.16


title: MPM002579

tag: studyCode = 25

tag: treatment = PS341

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 30-Oct-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PD

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 60

tag: PGx_CensorReason = Dex at 60days

tag: PGx_Alternative_Therapy = Dex at 60days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 425

tag: albumin = 43

tag: C_Reactive_Protein = 1

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 6

tag: meanMyelScore = 37.34


title: MPM002575

tag: studyCode = 25

tag: sex = Male

tag: race = Hispanic

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 9-Jul-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 799

tag: Days_Survived_From_Randomization = 890

tag: albumin = 35

tag: C_Reactive_Protein = 23

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 35.37

tag: TC_Class_2006 = D1


title: MPM002573

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 58

tag: Date_of_Randomization = 17-Jul-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 88

tag: PGx_CensorReason = Dex at 88 days

tag: PGx_Alternative_Therapy = Dex at 88 days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 192

tag: albumin = 27

tag: C_Reactive_Protein = 3.16

tag: Beta2_Microglobulin = 3.31

tag: meanMyelScore = 19.31


title: MPM002574

tag: studyCode = 25

tag: sex = Female

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 28-Aug-01

tag: Myeloma_Measure = IGG

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 805

tag: PGx_CensorReason = no further data

tag: PGx_Alternative_Therapy = no further data

tag: Days_Survived_From_Randomization = 805

tag: albumin = 35

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 6.6

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 38.35


title: MPM002577

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 12-Nov-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = MR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 139

tag: PGx_CensorReason = Dex at 139days

tag: PGx_Alternative_Therapy = Dex at 139days

tag: Days_Survived_From_Randomization = 764

tag: albumin = 34

tag: C_Reactive_Protein = 14

tag: Beta2_Microglobulin = 0.33

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 32.36