title: MPM002572

tag: studyCode = 25

tag: sex = Female

tag: Age_at_Randomization = 66

tag: Date_of_Randomization = 13-Nov-01

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 35

tag: PGx_CensorReason = Patient died

tag: PGx_Alternative_Therapy = Patient died

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 62

tag: albumin = 24

tag: C_Reactive_Protein = 18

tag: Beta2_Microglobulin = 33

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 70.52

tag: TC_Class_2006 = MAF


title: MPM002576

status: Public on Dec 06 2007

type: RNA

city: Cambridge

first: George

last: Mulligan

state: MA

address: 35 Landsdowne Stree

department: Clinical Development

country: USA

institute: Millennium Pharmaceuticals

description: Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

hyb_protocol: cRNA for each sample was hybridized in triplicate to the U133A/B array.  Data represent median of replicates that passed array QC.

scan_protocol: Microarrays were scanned with GeneArray 3000 scaner (Affymetrix).

data_processing: Dataprocessing used Affymetrix MAS5.0.

label: biotin

molecule: total RNA

organism: Homo sapiens

source_name: tumor sample

label_protocol: A standard T7 based amplification protocol (Affymetrix) was used to convert 2.0 microgram of RNA to biotinylated cRNA.

growth_protocol: tumor samples were collected during patient screening period prior to entry into clinical trials for the treatment of multiple myeloma

extract_protocol: Total RNA was isolated  using Qiagen RNAeasy kit

treatment_protocol: samples were subject to a rapid enrichment procedure (see details in http://bloodjournal.hematologylibrary.org/cgi/content/full/109/8/3177) and tumor cell pellet was frozen

tag: studyCode = 25

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 2-Nov-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 129

tag: PGx_CensorReason = Dex at 129days

tag: PGx_Alternative_Therapy = Dex at 129days

tag: Days_Survived_From_Randomization = 734

tag: albumin = 26

tag: C_Reactive_Protein = 36

tag: Beta2_Microglobulin = 1.48

tag: meanMyelScore = 25.87


title: MPM002579

tag: sex = Male

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 30-Oct-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 60

tag: PGx_CensorReason = Dex at 60days

tag: PGx_Alternative_Therapy = Dex at 60days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 425

tag: albumin = 43

tag: C_Reactive_Protein = 1

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 6

tag: meanMyelScore = 37.34


title: MPM002578

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: race = Black

tag: Age_at_Randomization = 44

tag: Date_of_Randomization = 16-Nov-01

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 536

tag: Days_Survived_From_Randomization = 760

tag: albumin = 36

tag: C_Reactive_Protein = 10

tag: Beta2_Microglobulin = 0.53

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 37.46


title: MPM002571

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 12-Jun-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 188

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 660

tag: albumin = 35

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 7.9

tag: Number_of_Prior_Lines = 14

tag: meanMyelScore = 20.53

tag: TC_Class_2006 = D2


title: MPM002586

tag: studyCode = 25

tag: treatment = PS341

tag: Age_at_Randomization = 48

tag: Date_of_Randomization = 23-Oct-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 41

tag: PGx_CensorReason = Dex at 41 days

tag: PGx_Alternative_Therapy = Dex at 41 days

tag: Days_Survived_From_Randomization = 524

tag: albumin = 28

tag: C_Reactive_Protein = 3.1

tag: Beta2_Microglobulin = 4.8

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 32.49

tag: Mayo_Clinic_ProliferativeIndex = 0.5


title: MPM002573

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 58

tag: Date_of_Randomization = 17-Jul-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 88

tag: PGx_CensorReason = Dex at 88 days

tag: PGx_Alternative_Therapy = Dex at 88 days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 192

tag: albumin = 27

tag: C_Reactive_Protein = 3.16

tag: Beta2_Microglobulin = 3.31

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 19.31


title: MPM002575

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: race = Hispanic

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 9-Jul-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = CR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 799

tag: Days_Survived_From_Randomization = 890

tag: albumin = 35

tag: C_Reactive_Protein = 23

tag: Beta2_Microglobulin = 3.4

tag: meanMyelScore = 35.37

tag: TC_Class_2006 = D1


title: MPM002570

tag: race = White

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 25-Sep-01

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 83

tag: PGx_CensorReason = Dex at 83 days

tag: PGx_Alternative_Therapy = Dex at 83 days

tag: Days_Survived_From_Randomization = 448

tag: albumin = 29

tag: C_Reactive_Protein = 0.7

tag: Beta2_Microglobulin = 3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 27.17


title: MPM002569

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 24-Jul-01

tag: Myeloma_Measure = IGA

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 82

tag: PGx_CensorReason = Dex at 82 days

tag: PGx_Alternative_Therapy = Dex at 82 days

tag: Days_Survived_From_Randomization = 876

tag: albumin = 32

tag: C_Reactive_Protein = 5.81

tag: Beta2_Microglobulin = 2.98

tag: meanMyelScore = 19.28

tag: TC_Class_2006 = D2


title: MPM002574

tag: race = White

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 28-Aug-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 805

tag: PGx_CensorReason = no further data

tag: PGx_Alternative_Therapy = no further data

tag: Days_Survived_From_Randomization = 805

tag: albumin = 35

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 6.6

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 38.35


title: MPM002577

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 12-Nov-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = MR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 139

tag: PGx_CensorReason = Dex at 139days

tag: PGx_Alternative_Therapy = Dex at 139days

tag: Days_Survived_From_Randomization = 764

tag: albumin = 34

tag: C_Reactive_Protein = 14

tag: Beta2_Microglobulin = 0.33

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 32.36


title: MPM002567

tag: studyCode = 25

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 48

tag: Date_of_Randomization = 16-Jul-01

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 83

tag: PGx_CensorReason = Dex at 83 days

tag: PGx_Alternative_Therapy = Dex at 83 days

tag: Days_Survived_From_Randomization = 358

tag: albumin = 39

tag: C_Reactive_Protein = 1.3

tag: Beta2_Microglobulin = 2.1

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 32.57

tag: TC_Class_2006 = D2


title: MPM002568

tag: studyCode = 25

tag: treatment = PS341

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 23-Jul-01

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 35

tag: PGx_CensorReason = Patient died

tag: PGx_Alternative_Therapy = Patient died

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 99

tag: albumin = 35.2

tag: C_Reactive_Protein = 9

tag: Beta2_Microglobulin = 9.6

tag: Number_of_Prior_Lines = 7

tag: meanMyelScore = 32.54

tag: TC_Class_2006 = None


title: MPM002565

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 58

tag: Date_of_Randomization = 10-Sep-01

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 79

tag: Days_Survived_From_Randomization = 544

tag: albumin = 35

tag: C_Reactive_Protein = 6.2

tag: Beta2_Microglobulin = 6.5

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 48.47


title: MPM002564

tag: studyCode = 25

tag: treatment = PS341

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 20-Jul-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Days_To_Progression = 42

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 178

tag: albumin = 27

tag: C_Reactive_Protein = 14.1

tag: Beta2_Microglobulin = 2.89

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 45.72


title: MPM002563

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 75

tag: Date_of_Randomization = 9-Jul-01

tag: Myeloma_Measure = UNK

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 51

tag: Days_Survived_From_Randomization = 66

tag: albumin = 26

tag: C_Reactive_Protein = 14.8

tag: Beta2_Microglobulin = 4.4

tag: Number_of_Prior_Lines = 8

tag: meanMyelScore = 42.72

tag: Mayo_Clinic_ProliferativeIndex = 2.38

tag: TC_Class_2006 = D2


title: MPM002566

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 9-Oct-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 35

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 411

tag: albumin = 31

tag: C_Reactive_Protein = 2.9

tag: Beta2_Microglobulin = 133

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 46.3


title: MPM002561

tag: race = White

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 20-Jun-01

tag: PGx_Progression(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 160

tag: albumin = 26

tag: C_Reactive_Protein = 62

tag: Beta2_Microglobulin = 0.74

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 33.43


title: MPM002562

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 39

tag: Date_of_Randomization = 14-May-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 36

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 628

tag: albumin = 45

tag: C_Reactive_Protein = 65

tag: Beta2_Microglobulin = 3.5

tag: meanMyelScore = 55.6


title: MPM002559

tag: race = Black

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 17-Apr-01

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 42

tag: Days_Survived_From_Randomization = 478

tag: albumin = 39

tag: C_Reactive_Protein = 11

tag: Beta2_Microglobulin = 5.6

tag: Number_of_Prior_Lines = 7

tag: meanMyelScore = 76.68

tag: TC_Class_2006 = D1


title: MPM002558

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 23-Apr-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 78

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 167

tag: albumin = 34

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 4

tag: Number_of_Prior_Lines = 5

tag: meanMyelScore = 54.21


title: MPM002560

tag: studyCode = 25

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 3-Dec-01

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 37

tag: Days_Survived_From_Randomization = 401

tag: albumin = 37

tag: C_Reactive_Protein = 12.8

tag: Beta2_Microglobulin = 12.3

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 35.92


title: MPM002557

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 23-Jul-01

tag: Myeloma_Measure = UNK

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 53

tag: PGx_CensorReason = Patient died

tag: PGx_Alternative_Therapy = Patient died

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 98

tag: C_Reactive_Protein = 16.6

tag: Beta2_Microglobulin = 3.6

tag: meanMyelScore = 29.1

tag: TC_Class_2006 = D1


title: MPM002556

tag: studyCode = 25

tag: race = White

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 9-Oct-01

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 89

tag: PGx_CensorReason = Dex at 89 days

tag: PGx_Alternative_Therapy = Dex at 89 days

tag: Days_Survived_From_Randomization = 671

tag: albumin = 32

tag: C_Reactive_Protein = 0.57

tag: Beta2_Microglobulin = 5.64

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 16.42


title: MPM002549

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 49

tag: Date_of_Randomization = 28-Oct-02

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 212

tag: PGx_CensorReason = Alternative therapy

tag: Days_Survived_From_Randomization = 590

tag: albumin = 34

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 17.75


title: MPM002548

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 30-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 14

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 66

tag: albumin = 28

tag: meanMyelScore = 28.44

tag: TC_Class_2006 = None


title: MPM002555

tag: studyCode = 25

tag: treatment = PS341

tag: race = White

tag: Date_of_Randomization = 15-Oct-01

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 147

tag: Days_Survived_From_Randomization = 212

tag: albumin = 27

tag: C_Reactive_Protein = 1.39

tag: Beta2_Microglobulin = 3

tag: Number_of_Prior_Lines = 6

tag: meanMyelScore = 25.72

tag: TC_Class_2006 = D1


title: MPM002551

tag: sex = Male

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 16-Oct-01

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 422

tag: PGx_CensorReason = no further data

tag: PGx_Alternative_Therapy = no further data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 662

tag: albumin = 30

tag: C_Reactive_Protein = 9.5

tag: Beta2_Microglobulin = 10.2

tag: meanMyelScore = 36.8


title: MPM002554

tag: studyCode = 25

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 9-Jul-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 609

tag: Days_Survived_From_Randomization = 691

tag: albumin = 42

tag: C_Reactive_Protein = 2

tag: Beta2_Microglobulin = 2.4

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 56.59

tag: TC_Class_2006 = D2


title: MPM002544

tag: studyCode = 40

tag: sex = Female

tag: Age_at_Randomization = 45

tag: Date_of_Randomization = 29-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 365

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Radiation treated day 365

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 636

tag: albumin = 32

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 53.32

tag: TC_Class_2006 = D1


title: MPM002553

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 9-Nov-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 119

tag: Days_Survived_From_Randomization = 237

tag: albumin = 20

tag: C_Reactive_Protein = 1

tag: Beta2_Microglobulin = 0.36

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 26.17


title: MPM002546

tag: studyCode = 40

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 7-Oct-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Days_To_Progression = 113

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 113

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 171

tag: albumin = 27

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 48.42


title: MPM002543

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 28-Oct-02

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 92

tag: PGx_Alternative_Therapy = Dex added atday 92

tag: Days_Survived_From_Randomization = 223

tag: albumin = 43

tag: meanMyelScore = 22.98

tag: TC_Class_2006 = D1


title: MPM002523

tag: studyCode = 40

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 45

tag: Date_of_Randomization = 22-Jul-02

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 109

tag: Days_Survived_From_Randomization = 135

tag: albumin = 40

tag: meanMyelScore = 42.01


title: MPM002522

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 11-Jul-02

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 63

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 945

tag: albumin = 37

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 54.16


title: MPM002525

tag: studyCode = 40

tag: race = Black

tag: Age_at_Randomization = 42

tag: Date_of_Randomization = 26-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: Days_Survived_From_Randomization = 383

tag: albumin = 42

tag: meanMyelScore = 39.79


title: MPM002519

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 8-Jul-02

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 210

tag: PGx_Alternative_Therapy = PD incorrect because of plasmaphere

tag: Days_Survived_From_Randomization = 458

tag: albumin = 19

tag: meanMyelScore = 35.14


title: MPM002521

tag: studyCode = 40

tag: Age_at_Randomization = 55

tag: Myeloma_Measure = IGA

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 168

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 230

tag: albumin = 34

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 76.24

tag: TC_Class_2006 = D1


title: MPM002512

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 11-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 203

tag: Days_Survived_From_Randomization = 547

tag: albumin = 43

tag: meanMyelScore = 40.71


title: MPM002498

tag: studyCode = 40

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 8-Oct-02

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 43

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 43

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 110

tag: albumin = 27

tag: meanMyelScore = 42.41


title: MPM002509

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 50

tag: Date_of_Randomization = 4-Jun-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 158

tag: PGx_CensorReason = Dex at 158 days

tag: PGx_Alternative_Therapy = Dex at 158 days

tag: Days_Survived_From_Randomization = 471

tag: albumin = 36

tag: Number_of_Prior_Lines = 6

tag: meanMyelScore = 44.74


title: MPM002508

tag: sex = Male

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 11-Jun-01

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 35

tag: PGx_CensorReason = Alt therapy - not clearly dex

tag: PGx_Alternative_Therapy = Alt therapy - not clearly dex

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 162

tag: albumin = 33

tag: C_Reactive_Protein = 6

tag: Beta2_Microglobulin = 3.3

tag: meanMyelScore = 45.04

tag: TC_Class_2006 = D2


title: MPM002501

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 41

tag: Date_of_Randomization = 16-May-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 741

tag: albumin = 50

tag: C_Reactive_Protein = 4.1

tag: Beta2_Microglobulin = 6.1

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 26.1

tag: Mayo_Clinic_ProliferativeIndex = 1.11

tag: TC_Class_2006 = D1


title: MPM002497

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 12-May-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 64

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 83

tag: albumin = 42

tag: C_Reactive_Protein = 104

tag: Beta2_Microglobulin = 23.3

tag: meanMyelScore = 70.85


title: MPM002506

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 27-Sep-01

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 138

tag: PGx_CensorReason = Alt therapy - not clearly dex

tag: PGx_Alternative_Therapy = Alt therapy - not clearly dex

tag: Days_Survived_From_Randomization = 447

tag: albumin = 31

tag: C_Reactive_Protein = 25

tag: Beta2_Microglobulin = 6.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 60.05


title: MPM002510

tag: studyCode = 25

tag: treatment = PS341

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 26-Mar-01

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 35

tag: Days_Survived_From_Randomization = 1058

tag: albumin = 38

tag: C_Reactive_Protein = 1

tag: Beta2_Microglobulin = 2.6

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 38.17

tag: TC_Class_2006 = D3


title: MPM002507

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 75

tag: Date_of_Randomization = 25-Sep-01

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 44

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 177

tag: albumin = 34

tag: C_Reactive_Protein = 9

tag: Beta2_Microglobulin = 7.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 43.51

tag: TC_Class_2006 = D1


title: MPM002505

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Female

tag: race = Black

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 18-Jun-01

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 322

tag: Days_Survived_From_Randomization = 785

tag: albumin = 37

tag: C_Reactive_Protein = 7

tag: Beta2_Microglobulin = 2.1

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 62.54


title: MPM002427

tag: studyCode = 25

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 28-Sep-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 44

tag: PGx_CensorReason = Dex at 44 days

tag: PGx_Alternative_Therapy = Dex at 44 days

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 307

tag: albumin = 45

tag: C_Reactive_Protein = 29

tag: Beta2_Microglobulin = 3.7

tag: meanMyelScore = 43.79

tag: TC_Class_2006 = D2


title: MPM002426

tag: studyCode = 25

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 27-Nov-01

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 182

tag: PGx_CensorReason = Patient died

tag: PGx_Alternative_Therapy = Patient died

tag: Days_Survived_From_Randomization = 219

tag: albumin = 30

tag: C_Reactive_Protein = 5

tag: Beta2_Microglobulin = 0.25

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 48.69

tag: TC_Class_2006 = D1


title: MPM002425

tag: race = White

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 22-Oct-01

tag: Myeloma_Measure = LIGHT-CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 281

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 434

tag: albumin = 36

tag: C_Reactive_Protein = 29.8

tag: Beta2_Microglobulin = 2.7

tag: meanMyelScore = 39.43


title: MPM002420

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 24-Mar-03

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 147

tag: Days_Survived_From_Randomization = 440

tag: albumin = 42

tag: C_Reactive_Protein = 4.5

tag: Beta2_Microglobulin = 3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 10.16


title: MPM002424

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 69

tag: Date_of_Randomization = 4-Mar-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 62

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 98

tag: albumin = 34

tag: C_Reactive_Protein = 27.3

tag: Beta2_Microglobulin = 14.9

tag: meanMyelScore = 30.78


title: MPM002416

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 28-Apr-03

tag: Myeloma_Measure = IGG

tag: PGx_Days_To_Progression = 45

tag: Days_Survived_From_Randomization = 229

tag: albumin = 38

tag: C_Reactive_Protein = 6.2

tag: Beta2_Microglobulin = 4.1

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 11.74

tag: TC_Class_2006 = D1


title: MPM002415

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 5-May-03

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 189

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 230

tag: albumin = 35

tag: Beta2_Microglobulin = 5.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 29.11

tag: TC_Class_2006 = D2


title: MPM002412

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 31-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 172

tag: Days_Survived_From_Randomization = 363

tag: albumin = 29

tag: Beta2_Microglobulin = 7.9

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 23.39

tag: TC_Class_2006 = D1


title: MPM002411

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 28-Apr-03

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 281

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 393

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 6.6

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 38.88


title: MPM002414

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 81

tag: Date_of_Randomization = 8-Mar-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 24

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 60

tag: albumin = 32

tag: Beta2_Microglobulin = 4.4

tag: meanMyelScore = 25.39


title: MPM002388

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 13-Dec-02

tag: PGx_Response = PD

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 46

tag: Days_Survived_From_Randomization = 240

tag: albumin = 38

tag: Beta2_Microglobulin = 7.7

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 75.18

tag: TC_Class_2006 = D1


title: MPM002409

tag: studyCode = 40

tag: sex = Female

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 27-Dec-02

tag: Myeloma_Measure = NON-SECRETO

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 536

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 13.55

tag: TC_Class_2006 = D3


title: MPM002389

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 65

tag: Date_of_Randomization = 17-Mar-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 169

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 684

tag: albumin = 43

tag: C_Reactive_Protein = 6.9

tag: Beta2_Microglobulin = 4.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 35.33

tag: TC_Class_2006 = D2


title: MPM002391

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 15-Apr-03

tag: Myeloma_Measure = IGG/IGA

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 140

tag: Days_Survived_From_Randomization = 654

tag: albumin = 41

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.8

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 11.13


title: MPM002410

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Date_of_Randomization = 3-Apr-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 442

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 645

tag: albumin = 42

tag: Beta2_Microglobulin = 4.4

tag: meanMyelScore = 30.74

tag: TC_Class_2006 = D1


title: MPM002371

tag: studyCode = 39

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 45

tag: Date_of_Randomization = 3-Jan-03

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 238

tag: Days_Survived_From_Randomization = 935

tag: albumin = 46

tag: C_Reactive_Protein = 4.6

tag: Beta2_Microglobulin = 1.5

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 29.31


title: MPM002387

tag: treatment = Dex

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 79

tag: Date_of_Randomization = 13-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 32

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 108

tag: albumin = 43

tag: Beta2_Microglobulin = 2.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 33.7


title: MPM002374

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 4-Feb-03

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 189

tag: Days_Survived_From_Randomization = 647

tag: albumin = 35

tag: C_Reactive_Protein = 30

tag: Beta2_Microglobulin = 3.1

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 37.64


title: MPM002359

tag: race = White

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 21-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 213

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 315

tag: albumin = 44

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.9

tag: meanMyelScore = 14.63

tag: TC_Class_2006 = D1


title: MPM002376

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Female

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 19-Aug-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 15

tag: Days_Survived_From_Randomization = 353

tag: albumin = 29

tag: C_Reactive_Protein = 5.9

tag: Beta2_Microglobulin = 9.3

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 25.2

tag: TC_Class_2006 = D2


title: MPM002373

tag: race = White

tag: Age_at_Randomization = 69

tag: Date_of_Randomization = 21-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 192

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 282

tag: albumin = 35

tag: C_Reactive_Protein = 4.8

tag: Beta2_Microglobulin = 3.5

tag: meanMyelScore = 42.02

tag: TC_Class_2006 = D1


title: MPM002356

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 2-Dec-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 105

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 955

tag: albumin = 44

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 34.43


title: MPM002363

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 79

tag: Date_of_Randomization = 25-Mar-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 126

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 274

tag: albumin = 0.025

tag: C_Reactive_Protein = 12

tag: Beta2_Microglobulin = 6.3

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 49.94


title: MPM002367

tag: studyCode = 39

tag: treatment = PS341

tag: race = Black

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 1-Oct-02

tag: PGx_Days_To_Progression = 392

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 966

tag: albumin = 43

tag: C_Reactive_Protein = 7.6

tag: Beta2_Microglobulin = 2.3

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 35.78

tag: TC_Class_2006 = D1


title: MPM002352

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 49

tag: Date_of_Randomization = 17-Mar-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 232

tag: Days_Survived_From_Randomization = 865

tag: albumin = 36

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3

tag: meanMyelScore = 20.37


title: MPM002351

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 7-Feb-03

tag: PGx_Response = CR

tag: PGx_Days_To_Progression = 213

tag: Days_Survived_From_Randomization = 657

tag: albumin = 39

tag: Beta2_Microglobulin = 5.6

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 15.7

tag: TC_Class_2006 = D2


title: MPM002350

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 78

tag: Date_of_Randomization = 28-Jan-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 276

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 514

tag: albumin = 41

tag: Beta2_Microglobulin = 3.3

tag: meanMyelScore = 30.72


title: MPM002343

tag: studyCode = 39

tag: sex = Male

tag: Age_at_Randomization = 72

tag: Date_of_Randomization = 20-Feb-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 85

tag: Days_Survived_From_Randomization = 262

tag: albumin = 45

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.7

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 35.25


title: MPM002332

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 16-Dec-02

tag: Myeloma_Measure = NON-SECRETO

tag: PGx_Response = PD

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 84

tag: Days_Survived_From_Randomization = 611

tag: albumin = 44

tag: Beta2_Microglobulin = 2.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 17.39


title: MPM002347

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 12-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 89

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 273

tag: albumin = 39

tag: C_Reactive_Protein = 8

tag: Beta2_Microglobulin = 5.7

tag: meanMyelScore = 12.09

tag: TC_Class_2006 = D1


title: MPM002326

tag: studyCode = 40

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 29-Jul-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 175

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 674

tag: albumin = 42

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 81.9


title: MPM002319

tag: treatment = PS341

tag: sex = Female

tag: race = Hispanic

tag: Age_at_Randomization = 51

tag: Date_of_Randomization = 7-Aug-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 37

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 943

tag: meanMyelScore = 34.87


title: MPM002338

tag: studyCode = 39

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 45

tag: Date_of_Randomization = 21-Oct-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Days_To_Progression = 87

tag: Days_Survived_From_Randomization = 131

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.9

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 18.2


title: MPM002345

tag: sex = Female

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 3-Feb-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 261

tag: Days_Survived_From_Randomization = 481

tag: albumin = 44

tag: C_Reactive_Protein = 8

tag: Beta2_Microglobulin = 4.6

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 23.46

tag: TC_Class_2006 = D2


title: MPM002307

tag: studyCode = 40

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 25-Nov-02

tag: PGx_Days_To_Progression = 235

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 660

tag: albumin = 42

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 38.45

tag: TC_Class_2006 = D1


title: MPM002317

tag: sex = Female

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 22-Jul-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = Alternative therapy

tag: Days_Survived_From_Randomization = 294

tag: meanMyelScore = 14.11


title: MPM002304

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = Black

tag: Age_at_Randomization = 73

tag: Date_of_Randomization = 17-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 73

tag: Days_Survived_From_Randomization = 211

tag: albumin = 23

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 10.26


title: MPM002305

tag: studyCode = 40

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 14-Feb-03

tag: PGx_Response = NC

tag: PGx_Days_To_Progression = 62

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 150

tag: albumin = 30

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 65.34

tag: TC_Class_2006 = D1


title: MPM002311

tag: sex = Male

tag: Age_at_Randomization = 36

tag: Date_of_Randomization = 12-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 87

tag: Days_Survived_From_Randomization = 129

tag: albumin = 42

tag: meanMyelScore = 53.64


title: MPM002303

tag: studyCode = 39

tag: treatment = Dex

tag: race = Other

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 13-Dec-02

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 221

tag: albumin = 22

tag: Beta2_Microglobulin = 11.2

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 27.52

tag: Mayo_Clinic_ProliferativeIndex = 0.79

tag: TC_Class_2006 = MAF


title: MPM002297

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 47

tag: Date_of_Randomization = 16-Jan-03

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 124

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 300

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 58.07


title: MPM002295

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 30-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = MR

tag: PGx_Days_To_Progression = 105

tag: Days_Survived_From_Randomization = 253

tag: albumin = 37

tag: C_Reactive_Protein = 74

tag: Beta2_Microglobulin = 3

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 39.58


title: MPM002294

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 17-Dec-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 267

tag: Days_Survived_From_Randomization = 884

tag: albumin = 40

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 4.8

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 45.79

tag: TC_Class_2006 = D1


title: MPM002291

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 25-Jun-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 113

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 113

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 486

tag: albumin = 33

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 47.19


title: MPM002283

tag: studyCode = 39

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 10-Feb-03

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 92

tag: Days_Survived_From_Randomization = 632

tag: albumin = 30

tag: C_Reactive_Protein = 3.4

tag: Beta2_Microglobulin = 6.9

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 21.56

tag: TC_Class_2006 = D2


title: MPM002284

tag: treatment = Dex

tag: sex = Female

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 4-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 282

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 741

tag: albumin = 33

tag: Beta2_Microglobulin = 4

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 20.63

tag: TC_Class_2006 = D1


title: MPM002277

tag: studyCode = 39

tag: treatment = PS341

tag: race = White

tag: Age_at_Randomization = 60

tag: Date_of_Randomization = 20-Jan-03

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 84

tag: Days_Survived_From_Randomization = 953

tag: albumin = 38

tag: C_Reactive_Protein = 4.1

tag: Beta2_Microglobulin = 2.3

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 19.15


title: MPM002265

tag: sex = Male

tag: Age_at_Randomization = 69

tag: Date_of_Randomization = 9-Dec-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Days_To_Progression = 64

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 939

tag: albumin = 40

tag: C_Reactive_Protein = 5

tag: Beta2_Microglobulin = 5.4

tag: meanMyelScore = 58.37


title: MPM002263

tag: studyCode = 39

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 71

tag: Date_of_Randomization = 16-Jan-03

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 253

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 761

tag: albumin = 35

tag: Beta2_Microglobulin = 8.8

tag: meanMyelScore = 44.93

tag: TC_Class_2006 = D2


title: MPM002288

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 57

tag: Date_of_Randomization = 12-Nov-02

tag: Myeloma_Measure = NON-SECRETO

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Days_To_Progression = 28

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 28

tag: Days_Survived_From_Randomization = 85

tag: albumin = 45

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 35.33

tag: Mayo_Clinic_ProliferativeIndex = 1.58


title: MPM002268

tag: sex = Female

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 46

tag: Date_of_Randomization = 23-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 38

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 116

tag: albumin = 22

tag: meanMyelScore = 60.78


title: MPM002260

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 72

tag: Date_of_Randomization = 27-Sep-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_Days_To_Progression = 42

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 70

tag: albumin = 32

tag: meanMyelScore = 21.55

tag: Mayo_Clinic_ProliferativeIndex = 1.73


title: MPM002259

tag: Date_of_Randomization = 26-Aug-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 119

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 346

tag: albumin = 35

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 23.37

tag: TC_Class_2006 = D1


title: MPM002258

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 20-Aug-02

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 85

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 85

tag: Days_Survived_From_Randomization = 701

tag: albumin = 37

tag: meanMyelScore = 44.27


title: MPM002250

tag: Age_at_Randomization = 71

tag: Date_of_Randomization = 2-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 154

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 250

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 36.69


title: MPM002243

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 7-Feb-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 268

tag: PGx_Alternative_Therapy = did get VELCADE 27 days later

tag: Days_Survived_From_Randomization = 712

tag: albumin = 43

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.6

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 14.9

tag: TC_Class_2006 = D2


title: MPM002251

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Date_of_Randomization = 26-Nov-02

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 92

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex aded at day 92

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 355

tag: albumin = 38

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 40.77

tag: TC_Class_2006 = D1


title: MPM002247

tag: studyCode = 39

tag: treatment = Dex

tag: race = White

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 6-Sep-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PD

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 97

tag: Days_Survived_From_Randomization = 648

tag: albumin = 48

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 21.4


title: MPM002242

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 21-Oct-02

tag: Myeloma_Measure = IGA

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 74

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 74

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 260

tag: albumin = 33

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 52.07


title: MPM002240

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 62

tag: Date_of_Randomization = 26-Nov-02

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 168

tag: Days_Survived_From_Randomization = 355

tag: albumin = 24

tag: meanMyelScore = 64.97

tag: TC_Class_2006 = D1


title: MPM002235

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 2-Dec-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 252

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 490

tag: albumin = 37

tag: meanMyelScore = 26.5


title: MPM002228

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 66

tag: Date_of_Randomization = 5-Aug-02

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 42

tag: Days_Survived_From_Randomization = 738

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 5.6

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 42.46


title: MPM002224

tag: Age_at_Randomization = 77

tag: Date_of_Randomization = 4-Dec-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 59

tag: albumin = 35

tag: Beta2_Microglobulin = 8.8

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 31.56

tag: TC_Class_2006 = D1


title: MPM002221

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Female

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 17-Jul-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 83

tag: Days_Survived_From_Randomization = 465

tag: albumin = 39

tag: C_Reactive_Protein = 6.1

tag: Beta2_Microglobulin = 3.1

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 34.46

tag: TC_Class_2006 = D2


title: MPM002232

tag: studyCode = 39

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 68

tag: Date_of_Randomization = 11-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 149

tag: Days_Survived_From_Randomization = 784

tag: albumin = 31

tag: C_Reactive_Protein = 67.8

tag: Beta2_Microglobulin = 6.6

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 17.93

tag: TC_Class_2006 = D1


title: MPM002220

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 5-Aug-02

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 168

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 336

tag: albumin = 41

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 44.53


title: MPM002241

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 7-Oct-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 434

tag: Days_Survived_From_Randomization = 619

tag: albumin = 38

tag: meanMyelScore = 15.01


title: MPM002216

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 64

tag: Date_of_Randomization = 26-Aug-02

tag: Myeloma_Measure = IGG

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 212

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex aded at day 212

tag: Days_Survived_From_Randomization = 461

tag: albumin = 44

tag: meanMyelScore = 25.39

tag: TC_Class_2006 = D1


title: MPM002215

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 41

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 119

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 181

tag: albumin = 46

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 45.77


title: MPM002214

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 39

tag: Date_of_Randomization = 26-Nov-02

tag: Myeloma_Measure = IGA

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 204

tag: Days_Survived_From_Randomization = 344

tag: albumin = 34

tag: meanMyelScore = 19.36


title: MPM002210

tag: studyCode = 39

tag: sex = Female

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 50

tag: Date_of_Randomization = 2-Sep-02

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 192

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 192

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.5

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 26.12

tag: TC_Class_2006 = D2


title: MPM002213

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 5-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 126

tag: Days_Survived_From_Randomization = 1001

tag: albumin = 37

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 13.84

tag: TC_Class_2006 = D1


title: MPM002211

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 72

tag: Date_of_Randomization = 11-Oct-02

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 133

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 191

tag: albumin = 32

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 4.9

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 34.26


title: MPM002209

tag: treatment = PS341

tag: sex = Male

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 46

tag: Date_of_Randomization = 30-Sep-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = CR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 324

tag: Days_Survived_From_Randomization = 1015

tag: albumin = 47

tag: Beta2_Microglobulin = 3.9

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 25.47


title: MPM002247

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 6-Sep-02

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 97

tag: Days_Survived_From_Randomization = 648

tag: albumin = 48

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2

tag: meanMyelScore = 21.4

tag: TC_Class_2006 = D2


title: MPM002204

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 25-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 287

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 501

tag: albumin = 43

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 30.12

tag: TC_Class_2006 = D1


title: MPM002202

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 2-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 252

tag: Days_Survived_From_Randomization = 732

tag: albumin = 37

tag: meanMyelScore = 39.9


title: MPM002206

tag: studyCode = 39

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 56

tag: Date_of_Randomization = 26-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = ?

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 66

tag: albumin = 34

tag: C_Reactive_Protein = 120

tag: Beta2_Microglobulin = 5.2

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 72.87


title: MPM002200

tag: studyCode = 40

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 58

tag: Date_of_Randomization = 24-Oct-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 84

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 345

tag: albumin = 42

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 37.87

tag: TC_Class_2006 = D2


title: MPM002199

tag: treatment = PS341

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 26-Nov-02

tag: Myeloma_Measure = NON-SECRETO

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 280

tag: Days_Survived_From_Randomization = 375

tag: albumin = 40

tag: meanMyelScore = 24.5

tag: Mayo_Clinic_ProliferativeIndex = 1.06


title: MPM002179

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 21-Oct-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 189

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 804

tag: albumin = 29

tag: C_Reactive_Protein = 4.4

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 14.24


title: MPM002187

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 31-May-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 206

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 1124

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 48.98

tag: TC_Class_2006 = D2


title: MPM002172

tag: sex = Male

tag: race = White

tag: Date_of_Randomization = 24-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 793

tag: Days_Survived_From_Randomization = 883

tag: albumin = 37

tag: meanMyelScore = 14.01


title: MPM002188

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 10-Jun-02

tag: PGx_Response = PR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 156

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 156

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 377

tag: albumin = 34

tag: meanMyelScore = 50.53

tag: TC_Class_2006 = D1


title: MPM002189

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 75

tag: Date_of_Randomization = 17-Jun-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 179

tag: Days_Survived_From_Randomization = 521

tag: albumin = 33

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 58.28

tag: TC_Class_2006 = D2


title: MPM002126

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 49

tag: Date_of_Randomization = 21-Oct-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 84

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 653

tag: albumin = 43

tag: meanMyelScore = 29.48


title: MPM002132

tag: studyCode = 39

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 51

tag: Date_of_Randomization = 14-Oct-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 252

tag: Days_Survived_From_Randomization = 884

tag: albumin = 42

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.1

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 26.34

tag: TC_Class_2006 = D1


title: MPM002173

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 15-Nov-02

tag: PGx_Response = PD

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 45

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 241

tag: albumin = 35

tag: Beta2_Microglobulin = 6.2

tag: meanMyelScore = 25.68


title: MPM002137

tag: treatment = PS341

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 76

tag: Date_of_Randomization = 30-Aug-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 585

tag: PGx_CensorReason = Study cutoff, 14DEC2003

tag: Days_Survived_From_Randomization = 1054

tag: albumin = 37

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.1

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 9.61


title: MPM002241

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 59

tag: Date_of_Randomization = 7-Oct-02

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 434

tag: Days_Survived_From_Randomization = 619

tag: albumin = 38

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 15.01


title: MPM002127

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 20-May-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 175

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 392

tag: meanMyelScore = 38.77


title: MPM002192

tag: studyCode = 39

tag: treatment = Dex

tag: Age_at_Randomization = 86

tag: Date_of_Randomization = 11-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 84

tag: Days_Survived_From_Randomization = 504

tag: albumin = 34

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 4.5

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 17.23

tag: TC_Class_2006 = D2


title: MPM002125

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 70

tag: Date_of_Randomization = 30-Sep-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 93

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 93

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 110

tag: albumin = 35

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 45.1


title: MPM002124

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 14-May-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PD

tag: PGx_Days_To_Progression = 84

tag: PGx_Alternative_Therapy = Dex added at day 84

tag: Days_Survived_From_Randomization = 241

tag: meanMyelScore = 42.8

tag: TC_Class_2006 = D1


title: MPM002123

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 47

tag: Date_of_Randomization = 7-May-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = IE

tag: PGx_Responder = IE

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 1117

tag: meanMyelScore = 18.2


title: MPM002204

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Male

tag: Age_at_Randomization = 54

tag: Date_of_Randomization = 25-Nov-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Days_To_Progression = 287

tag: Days_Survived_From_Randomization = 501

tag: albumin = 43

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 30.12


title: MPM002202

tag: sex = Female

tag: race = White

tag: Age_at_Randomization = 74

tag: Date_of_Randomization = 2-Dec-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 252

tag: Days_Survived_From_Randomization = 732

tag: albumin = 37

tag: meanMyelScore = 39.9

tag: TC_Class_2006 = D2


title: MPM002111

tag: studyCode = 39

tag: treatment = PS341

tag: Age_at_Randomization = 49

tag: Date_of_Randomization = 12-Sep-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 84

tag: Days_Survived_From_Randomization = 194

tag: albumin = 39

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 2.8

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 25.17


title: MPM002106

tag: studyCode = 40

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 52

tag: Date_of_Randomization = 19-Aug-02

tag: PGx_Days_To_Progression = 86

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 86

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 277

tag: albumin = 35

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 44.26

tag: TC_Class_2006 = D1


title: MPM002209

tag: studyCode = 39

tag: treatment = PS341

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 46

tag: Date_of_Randomization = 30-Sep-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = CR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 324

tag: Days_Survived_From_Randomization = 1015

tag: albumin = 47

tag: C_Reactive_Protein = 4

tag: Beta2_Microglobulin = 3.9

tag: Number_of_Prior_Lines = 1

tag: meanMyelScore = 25.47


title: MPM002179

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 21-Oct-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 189

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 804

tag: albumin = 29

tag: C_Reactive_Protein = 4.4

tag: Beta2_Microglobulin = 3.4

tag: Number_of_Prior_Lines = 2

tag: meanMyelScore = 14.24


title: MPM002105

tag: studyCode = 40

tag: treatment = PS341

tag: Age_at_Randomization = 63

tag: Date_of_Randomization = 19-Aug-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = MR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 227

tag: Days_Survived_From_Randomization = 434

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 38.38


title: MPM002188

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 61

tag: Date_of_Randomization = 10-Jun-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = PR

tag: PGx_Days_To_Progression = 156

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added at day 156

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 377

tag: albumin = 34

tag: meanMyelScore = 50.53

tag: TC_Class_2006 = D1


title: MPM002104

tag: studyCode = 40

tag: treatment = PS341

tag: race = Asian/Pacific Islander

tag: Age_at_Randomization = 48

tag: Date_of_Randomization = 13-Aug-02

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 105

tag: Days_Survived_From_Randomization = 968

tag: albumin = 37

tag: meanMyelScore = 30.96


title: MPM002090

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 55

tag: Date_of_Randomization = 20-Sep-02

tag: Myeloma_Measure = LIGHT CHAIN

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 87

tag: PGx_CensorReason = No more data

tag: Days_Survived_From_Randomization = 106

tag: albumin = 41

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 21.2


title: MPM002092

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 53

tag: Date_of_Randomization = 23-Sep-02

tag: Myeloma_Measure = IGA

tag: PGx_Response = PR

tag: PGx_Responder = R

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 158

tag: PGx_CensorReason = Alternative therapy

tag: PGx_Alternative_Therapy = Dex added day 158

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 212

tag: albumin = 32

tag: meanMyelScore = 24.26


title: MPM002097

tag: race = White

tag: Age_at_Randomization = 66

tag: Date_of_Randomization = 22-Oct-02

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 85

tag: PGx_Alternative_Therapy = Dex added at day 85

tag: Days_Survived_From_Randomization = 184

tag: albumin = 29

tag: Number_of_Prior_Lines = 4

tag: meanMyelScore = 51.4

tag: TC_Class_2006 = D3


title: MPM002091

tag: studyCode = 40

tag: treatment = PS341

tag: sex = Female

tag: Age_at_Randomization = 67

tag: Date_of_Randomization = 30-Sep-02

tag: PGx_Progression(0=No,1=Yes) = 1

tag: PGx_Days_To_Progression = 136

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 372

tag: albumin = 38

tag: meanMyelScore = 12.3


title: Pseudomonas aeruginosa_sodium hypochlorite_replicate3

status: Public on Dec 04 2007

city: Singapore

first: Matthew

middle: Wook

last: Chang

address: 62 Nanyang Drive

department: School of Chemical and Biomedical Engineering

country: Singapore

institute: Nanyang Technological University

description: sodium hypochlorite treatment

hyb_protocol: Standard Affymetrix procedures

scan_protocol: Standard Affymetrix procedures (target signal value was 150)

data_processing: Affymetrix GeneChip Opererating Software (GCOS) version 1.2

label: Biotin

organism: Pseudomonas aeruginosa

label_protocol: Approximately 12 µg of total RNA was processed to produce biotinylated cDNA targets.

growth_protocol: (i) we initiated P. aeruginosa cultures at 37°C with shaking at 250 rpm using sterilized Luria-Bertani (LB) broth, (ii) after 17 hours, we diluted the overnight cultures 1:100 in pre-warmed LB broth and incubated at 37°C with shaking at 250 rpm until OD600 reached the early logarithmic phase (~ 0.8), and (iii) we re-diluted the cells 1:10 in pre-warmed LB broth and incubated at 37°C with shaking at 250 rpm.  Then, we added 4.4mM sodium hypochlorite immediately after OD600 reached 0.8.

extract_protocol: Total RNA was isolated after 20 min incubation with sodium hypochlorite using RNeasy Mini kit (Qiagen, Inc., Valencia, CA) according to the manufacturer’s protocol.

treatment_protocol: sodium hypochlorite (4.4mM)

tag: PA01 Wild type


title: Pseudomonas aeruginosa_sodium hypochlorite_replicate2

description: sodium hypochlorite treatment


title: Pseudomonas aeruginosa_sodium hypochlorite_replicate1

description: sodium hypochlorite treatment


title: Pseudomonas aeruginosa_sodium hypochlorite_replicate4

description: sodium hypochlorite treatment


title: Pseudomonas aeruginosa_sodium hypochlorite_replicate5

description: sodium hypochlorite treatment


title: CCH-Hippocampus (CCH-H-1)

city: La Jolla

first: Dan

last: Zhou

state: CA

address: CMG 103, 9500 Gilman Drive, MC0735

department: Pediatrics

institute: University of California, San Diego, School of Medicine

description: This sample is a mouse hippocampus following 2 weeks of chronic consistent hypoxia (CCH) treatment started at postnatal day 2.

hyb_protocol: Hybridizations were carried out by using the Illumina gene expression system according to the manufacturer's instructions.

scan_protocol: Illumina scanner

data_processing: Raw data were aquired using BeadStudio 2.0.  The background were subtracted and normalised.  The "Null" value denotes expression below background (p < 0.01).

organism: Mus musculus

source_name: Hippocampus

label_protocol: Illumina® TotalPrep™ RNA Amplification Kit following the manufacturer's instructions. Input amount: 100ng of total RNA.

extract_protocol: Total RNA was extracted from frozen tissues of using RNeasy kit (Qiagen, Valencia, CA) according to the manufacturer's instructions.

tag: Strain

tag: Gender

value: male

tag: Age

value: 16 days

tag: Tissue

value: Hippocampus


title: Control-Hippocampus (C-H-1)

description: This sample is a control for mouse hippocampus following 2 weeks of chronic hypoxia treatment.


title: CIH-Hippocampus (CIH-H-1)

description: This sample is a mouse hippocampus following 2 weeks of chronic intermittent hypoxia (CIH) treatment started at postnatal day 2.


title: CIH-Hippocampus (CIH-H-3)


title: CIH-Cortex (CIH-C-1)

description: This sample is a mouse cortex following 2 weeks of chronic intermittent hypoxia (CIH) treatment started at postnatal day 2.

source_name: cortex

value: Cortex


title: CCH-Hippocampus (CCH-H-2)


title: Control-Cortex (C-C-1)

description: This sample is a control for mouse cortex following 2 weeks of chronic hypoxia treatment.


title: CIH-Cortex (CIH-C-2)


title: CCH-Hippocampus (CCH-H-3)


title: Control-Cortex (C-C-2)


title: CCH-Cortex (CCH-C-2)

description: This sample is a mouse cortex following 2 weeks of chronic consistent hypoxia treatment started at postnatal day 2.


title: Control-Hippocampus (C-H-3)

description: This sample is a control mouse hippocampus at age of 16 days.


title: CIH-Cortex (CIH-C-3)


title: Control-Hippocampus (C-H-2)


title: CCH-Cortex (CCH-C-3)


title: Control-Cortex (C-C-3)


title: CIH-Hippocampus (CIH-H-2)


title: CCH-Cortex (CCH-C-1)


title: IDNkB_O_1L_EtOH

status: Public on Dec 01 2007

city: Stanford

first: Howard

address: CCSR 2142

department: Dermatology

institute: Stanford University

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59971.gif; format: GIF

data_processing: VALUE is Log (base 2) of the ratio of the median of Channel 2 (usually 635 nm) to Channel 1 (usually 532 nm)

source_name: Universal Mouse Reference

tag: Universal Mouse Reference

source_name: DomNegNFkB old 1L_EtOH

tag: DomNegNFkB old 1L_EtOH


title: J1 ES cells untreated

status: Public on Oct 31 2007

first: J. Mauro

last: Calabrese

address: 40 Ames Street

department: Biology

institute: MIT

description: To better understand Dicer function, and the potential mechanisms by which RNAi contributes to pluripotency, short RNA expression was profiled from 4 ES cell libraries: 2 made from a Dicer-conditional ES cell line before and several months after deletion of Dicer, and 2 made before and 5 days after demethylation of J1 ES cells with 5-aza-deoxycytidine.

data_processing:
Sequences were extracted from 454 reads that had 10 bp of perfect match to the ligated adaptors (measuring from the 3' end of the 5' adaptor and 5' end of the 3' adaptor).
Contributed here are the unannotated sequence data from each library, including those sequences that did not match the mouse genome or any known non-coding RNAs.

source_name: J1 ES cells untreated

extract_protocol: Trizol, miRVana (Ambion) purify <200 nt fraction

treatment_protocol: untreated

tag: J1 ES cells


title: J1 ES cells 5-aza-deoxycytidine

source_name: J1 ES cells 5-aza-deoxycytidine

extract_protocol: Trizol, miRVana (Ambion) purify <200 bp RNA

treatment_protocol: 5 days after treatment with 5-aza-deoxycytidine


title: IDNkB_O_3R_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59975.gif; format: GIF

source_name: DomNegNFkB old 3R_4OHT

tag: DomNegNFkB old 3R_4OHT


title: IDNkB_O_1R_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59978.gif; format: GIF

source_name: DomNegNFkB old 1R_4OHT

tag: DomNegNFkB old 1R_4OHT


title: IDNkB_O_6L_EtOH

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59963.gif; format: GIF

source_name: DomNegNFkB old 6L_EtOH

tag: DomNegNFkB old 6L_EtOH


title: IDNkB_Y_1A-_EtOH

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59960.gif; format: GIF

source_name: DomNegNFkB young 1A-_EtOH

tag: DomNegNFkB young 1A-_EtOH


title: EDL-t10; transgenic extensor digitorum longus 10 month

status: Public on Jul 21 2006

city: Athens

first: Despina

last: Sanoudou

address: Soranou Efesiou 4

department: Molecular Biology

country: Greece

institute: Foundation for Biomedical Research, Academy of Athens

description:
Transgenic for alpha tropomyosin slow, snap frozen, extensor digitorum longus muscle, 10 month age animal

The CEL file for this submission could not be fully recovered; the linked supplementary file is approximately 75% complete

hyb_protocol: standard Affymetrix procedures

scan_protocol: standard Affymetrix procedures

data_processing: Affymetrix Microarray Suite version 5.0

source_name: extensor digitorum longus muscle

label_protocol: Approximately 8 µg of total RNA was processed to produce biotinylated cRNA targets.

extract_protocol: Standard Trizol protocol extraction. Total RNA pools from 3-5 mice were processed and hybridized to each microarray.

tag: Transgenic, snap frozen, extensor digitorum longus muscle, 10 month age animal


title: IDNkB_O_2R_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59977.gif; format: GIF

source_name: DomNegNFkB old 2R_4OHT

tag: DomNegNFkB old 2R_4OHT


title: IDNkB_Y_2A+_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59959.gif; format: GIF

source_name: DomNegNFkB young 2A+_4OHT

tag: DomNegNFkB young 2A+_4OHT


title: IDNkB_O_4L_EtOH

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59966.gif; format: GIF

source_name: DomNegNFkB old 4L_EtOH

tag: DomNegNFkB old 4L_EtOH


title: IDNkB_O_3L_EtOH

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59968.gif; format: GIF

source_name: DomNegNFkB old 3L_EtOH

tag: DomNegNFkB old 3L_EtOH


title: IDNkB_O_2L_EtOH

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59969.gif; format: GIF

source_name: DomNegNFkB old 2L_EtOH

tag: DomNegNFkB old 2L_EtOH


title: IDNkB_O_6R_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59962.gif; format: GIF

source_name: DomNegNFkB old 6R_4OHT

tag: DomNegNFkB old 6R_4OHT


title: IDNkB_O_4R_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59974.gif; format: GIF

source_name: DomNegNFkB old 4R_4OHT

tag: DomNegNFkB old 4R_4OHT


title: IDNkB_O_5R_4OHT

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59972.gif; format: GIF

source_name: DomNegNFkB old 5R_4OHT

tag: DomNegNFkB old 5R_4OHT


title: IDNkB_O_5L_EtOH

description:
Simple annotation: aging, Skin
Image: http://smd.stanford.edu/MicroArray/gifs/2005-03/59965.gif; format: GIF

source_name: Universal Mouse Reference

source_name: DomNegNFkB old 5L_EtOH

tag: DomNegNFkB old 5L_EtOH


title: Total RNA from Drosophila Embryo at 4-6 hrs

status: Public on Aug 14 2006

city: Santa Clara

first: Thomas

middle: R

last: Gingeras

address: 3380 Central Expressway

institute: Affymetrix, Inc.

description:
Total RNA was extracted from whole embryos ground in liquid nitrogen using Trisol reagent. RNA was then treated with RNAse-free DNAse I (Roche), 1U/ug of RNA, for 20 min at 37C.and purified using an RNAeasy kit (Qiagen).
First-strand cDNA synthesis was performed using SuperScript II reverse transcriptase (Invitrogen) in the reaction volume of 105 ul for 15 ug of starting RNA material. RNA was mixed with random hexamers (83.3 ng/ g of mRNA; Invitrogen)  heated to 70C for 10 min and cooled to 15C after which 5x Superscript II First Strand buffer (Invitrogen), DTT ( 10 mM)  and dNTPs ( 0.5 mM) were added. Superscript II RTase was added after a 20 min incubation (200Units/ug of RNA; Invitrogen) followed by a 20 min ramp to 42C and 60 min incubation at 42C. SuperScript II was inactivated  at 75C for 15 min.
Second-strand cDNA was synthesized by addition of  50U of E. coli DNA Ligase, 200U of E. coli DNA polymerase I, and 10U of E. coli RNAseH and 0.2mM dNTPs to the first-strand synthesis reaction at 16C for 2 hours (all reagents were from Invitrogen).
Double-stranded cDNA is treated with RNAseH (Epicentre) and RNAses A/T1 (Ambion), extracted using QIAquick PCR purification kit (Qiagen) and subjected to further fragmentation to 50-100 bp by DNAse I (1U/ul; Epicentre, size distribution of fragmented DNA was verified on a 2% agarose gel) . The fragmented cDNA was then end-labeled with 70nM of bio-ddATP (Perkin Elmer) using 6-10U of terminal transferase (TdT, Roche) per 1ug of fragmented DNA in 1x TdT buffer (Roche) and 5mM CoCl2 (Roche) for 2 hours at 37C. The labeled DNA material was subsequently hybridized to the microarrays for 18 hours at 45C in a 3 M TMAC/1X MES-based solution.

data_processing: RNA abundance was estimated using a Wilcoxon Sign Rank Scan Statistic where the median of all pairwise average values of PM-MM is calculated for all probe pairs within a sliding window of 101bp of CHR_POS using quantile normalizing replicate arrays whose median array intensity was scaled to 38.

organism: Drosophila melanogaster

source_name: Whole Embryo at 4-6 hrs

tag: Embryo at 4-6 hrs


title: Total RNA from Drosophila Embryo at 12-14 hrs

source_name: Whole Embryo at 12-14 hrs

tag: Embryo at 12-14 hrs


title: Total RNA from Drosophila Embryo at 8-10 hrs

source_name: Whole Embryo at 8-10 hrs

tag: Embryo at 8-10 hrs


title: Total RNA from Drosophila Embryo at 16-18 hrs

source_name: Whole Embryo at 16-18 hrs

tag: Embryo at 16-18 hrs


title: Total RNA from Drosophila Embryo at 10-12 hrs

source_name: Whole Embryo at 10-12 hrs

tag: Embryo at 10-12 hrs


title: Total RNA from Drosophila Embryo at 6-8 hrs

source_name: Whole Embryo at 6-8 hrs

tag: Embryo at 6-8 hrs


title: Total RNA from Drosophila Embryo at 14-16 hrs

source_name: Whole Embryo at 14-16 hrs

tag: Embryo at 14-16 hrs


title: Total RNA from Drosophila Embryo at 0-2 hrs

source_name: Whole Embryo at 0-2 hrs

tag: Embryo at 0-2 hrs


title: Total RNA from Drosophila Embryo at 18-20 hrs

source_name: Whole Embryo at 18-20 hrs

tag: Embryo at 18-20 hrs


title: Total RNA from Drosophila Embryo at 2-4 hrs

source_name: Whole Embryo at 2-4 hrs

tag: Embryo at 2-4 hrs


title: Total RNA from Drosophila Embryo at 22-24 hrs

source_name: Whole Embryo at 22-24 hrs

tag: Embryo at 22-24 hrs


title: Total RNA from Drosophila Embryo at 20-22 hrs

source_name: Whole Embryo at 20-22 hrs

tag: Embryo at 20-22 hrs


title: KD3019 C   56d

status: Public on Dec 13 2007

first: Stephen

last: Popper

department: Division of Infectious Diseases, Dept. of Medicine

description:
Whole blood RNA (PAXgene tubes) was collected from 20 Kawasaki patients during the acute, sub-acute (post-IVIG treatment) and convalescent phases of the disease
Image: http://smd.stanford.edu/MicroArray/gifs/2003-05/40457.gif
Disease State: C
Individual: KD3019

hyb_protocol: not provided

scan_protocol: Feature Extraction; Software and parameters for feature extraction.; Protocol Type = Feature Extraction; Parameter Image Origin = 1280, 5840; Parameter Datafile type = GenePix Results 3; Software: type: feature extraction; Performer: Stephen,,Popper Scanning parameters - Channel 1; Parameters for laser scanning of a hybridized array in channel 1.; Protocol Type = Scanning parameters; Parameter Scanner Make = Axon Instruments (V1.00); Parameter Scan Temperature = 38.56; Parameter Scan Time = 09:20:41; Parameter PMT Volts = 520; Parameter Scan Date = 2003-04-25; Parameter Pixel Size = 10; Parameter Laser on time = 91508; Parameter Focus Position = 0; Parameter Scanner Model = GenePix 4000A [47263]; Parameter Laser Power = 1.36; Parameter Scan Power = 100; Parameter Scanning software version = 2.0.2.3; Parameter Scanning software = AxImageIO; Performer: Stephen,,Popper Scanning parameters - Channel 2; Parameters for laser scanning of a hybridized array in channel 2.; Protocol Type = Scanning parameters; Parameter Scanner Make = Axon Instruments (V1.00); Parameter Scan Temperature = 38.56; Parameter Scan Time = 09:20:41; Parameter PMT Volts = 660; Parameter Scan Date = 2003-04-25; Parameter Pixel Size = 10; Parameter Laser on time = 456617; Parameter Focus Position = 0; Parameter Scanner Model = GenePix 4000A [47263]; Parameter Laser Power = 2.19; Parameter Scanning software version = 2.0.2.3; Parameter Scan Power = 100; Parameter Scanning software = AxImageIO; Performer: Stephen,,Popper

source_name: Stratagene Universal Human Reference RNA, 1st rnd amp AW 11/01/01, 3ug

label_protocol: not provided

extract_protocol: not provided

tag: Simple annotation

value: Infection, Whole blood

tag: Disease State

value: C

tag: Individual

source_name: KD 3019 56d Paxgene Ambion amp 4ug


title: MPM002414

description: Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

source_name: tumor sample

tag: studyCode = 39

tag: treatment = Dex

tag: sex = Male

tag: race = White

tag: Age_at_Randomization = 81

tag: Date_of_Randomization = 8-Mar-03

tag: Myeloma_Measure = IGG

tag: PGx_Response = NC

tag: PGx_Responder = NR

tag: PGx_Days_To_Progression = 24

tag: PGx_CensorReason = No more data

tag: Did_Patient_Die(0=No,1=Yes) = 1

tag: Days_Survived_From_Randomization = 60

tag: albumin = 32

tag: Beta2_Microglobulin = 4.4

tag: Number_of_Prior_Lines = 3

tag: meanMyelScore = 25.39