title: LIVER_METRONIDAZOLE_1500mg/kg_3days_exp4477_rep1_18919

description:
HybID: 18919
treated sample for experiment (RepID) 4477
replicate 1 of 2
Experimental sample
Replicate experimental sample: GSM222902: LIVER_METRONIDAZOLE_1500mg/kg_3days_exp4477_rep2_18920
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METRONIDAZOLE, 1500mg/kg, 3 days

value: 3 days


title: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_5days_exp6319_rep1_86665

status: Public on Mar 28 2008

type: RNA

city: Mountain View

first: Jeremy

last: Gollub

state: CA

address: 325 E. Middlefield Rd.

country: USA

institute: Iconix Biosciences

description:
HybID: 86665
treated sample for experiment (RepID) 6319
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220539: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_5days_exp6319_rep3_86666
Replicate experimental sample: GSM220538: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_5days_exp6319_rep2_86667
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

hyb_protocol: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44. 12.5 ug of cRNA sample was fragmented in 40 mM Tris-acetate (TrisOAc) pH7.9, 100 mM KOAc and 31.5 mM MgOAc at 94oC for 20 min. This typically resulted in a fragmented cRNA with a size range between 100 to 200 bases. 10 ug of the fragmented cRNA was used for hybridization of each Rat-Uniset I (RU1) Expression BioArray (Amersham Biosciences, Piscataway, NJ) in a volume of 260 ul, containing 78 ul of CodeLink Hyb buffer component A and 130 ul of CodeLink Hyb buffer component B (Amersham Biosciences, Piscataway, NJ). The hybridization solution was denatured at 90oC for 5 min then chilled on ice. The sample was vortexed at maximum speed for 5 sec and centrifuged at maximum speed for 5 min before 250 ul of the solution was injected into the inlet port of the flex-hybridization chamber, and placed in a CodeLink 12-slide shaker tray. The hybridization ports were sealed with 1 cm sealing strips (Amersham Biosciences, Piscataway, NJ), and the shaker tray(s) containing the slides was loaded into a New Brunswick Innova 4080 shaking incubator, with the hybridization chambers facing up. Slides were incubated for 20 hr at 37oC, while shaking at 300 rpm. The 12-slide shaker tray was removed from the shaker, and the hybridization chamber removed from each slide. Each slide was placed into the BioArray Rack of the Parallel Processing Tool (Amersham Biosciences, Piscataway, NJ) and incubated with 0.75x TNT (0.075 M Tris-HCl, pH7.6, 0.1125 M NaCl, 0.0375 % Tween-20) at 46oC for 1hr. The BioArray Rack was moved from the TNT containing reservoir to the small reagent reservoir containing 1:500 dilution of streptavidin-Alexa 647 (Molecular Probes, Eugene, OR). The signal was developed for 30 min at room temperature, before the reaction was stopped and slides were washed four times for 5 min each in TNT buffer (0.1 M Tris-HCl, pH7.6, 0.15 M NaCl, 0.05% Tween-20) using a large reagent reservoir. The slides were rinsed in ddH2O with 0.05% Tween-20 twice for 5 sec each before they were dried by centrifugation with a Qiagen Sigma 4-15C centrifuge (Valencia, CA) using a swinging bucket rotor (2x96) for exactly 3 min at 2000rpm (acceleration at position 9 and deceleration at position 9). The dried slides were stored in light protective slide boxes at room temperature prior to scanning.

scan_protocol: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44. The Axon GenePix Scanner (Axon Instrument, Union City, CA) was calibrated using the Calibration Slide supplied by Axon Instrument with GenePix 4.0 at 635 nm using the Calibration System. After calibration of the scanner, all processed slides were scanned with the laser set to 635 nm, the photomultiplier tube (PMT) voltage to 600 and the scan resolution to 10 microns. For consistency all slides were scanned the same day of color development, within an hour after dry spinning them and the data was analyzed using the CodeLink Expression Analysis Software version 2.2.25 (Amersham Biosciences, Piscataway, NJ).

data_processing: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44, supplemental methods.  Prior to statistical computation, the spot reading data was normalized. For this purpose a new nonlinear normalization procedure, similar to the centralization approach reported in the literature (Zien et al., 2001) was developed for the CodeLink array platform. The normalization procedure uses proprietary algorithm that assumes that in general, for an array with many probes, the majority of the signal represents genes that have unchanged expressions compared to controls, with the extreme values representing the true biology of the process and not some artifact due to measurement noise. The algorithm does not make the assumption that the true mRNA abundance being measured is linearly proportional to the spot reading signal or any assumption about the error distribution of such signals or their differential. Rather, the assumption of unchanged signals representing the bulk of the signal measurements is used to center a nonlinear curve fit to a reference template. This reference template is constructed for a large set of time matched, same tissue and same vehicle, control arrays, computing a median log signal for each probe. The replicate size of this set is adequate to ensure very small random error in the ensemble signal level for each reference probe. The curve fit corrects for some array processing problems, such as partial signal saturation, and improves the overall quality of the data compared to simple linear normalization methods. Essentially the curve tracks the mode of the signal distribution for sets of genes against the expected value for that set.

label: biotin

molecule: polyA RNA

organism: Rattus norvegicus

source_name: LIVER, ALPHA-NAPHTHOFLAVONE, 80mg/kg, 5 days

label_protocol: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44. The methods used for cRNA preparation (cDNA synthesis, cRNA preparation, and cRNA purification) are essentially as described in the CodeLink™ manual v2.1 as supplied by Amersham Biosciences (Piscataway, NJ) using the Qiagen BioRobot 9604 (Valencia, CA). cDNA synthesis, cRNA preparation, and cRNA purification were completely processed in a 96-well format using the automated Qiagen BioRobot 9604 procedure. 0.6 – 20 ìg of enriched RNA from different tissue sources were added to a reaction mixture in a final volume of 12 ìl, containing bacterial control RNA (1.5pg FixA, 5pgYjeK, 5pg AraB, 15pg EntF, 50pg FixB, 150pg HisB, 500pg LeuB, 1500pg gnd) and 1.0 ìl of 100 pmol ìl-1 T7-(dT)24 oligonucleotide primer (Proligo, Boulder, CO). The T7-(dT)24 oligonucleotide primer used, is an HPLC purified 63-mer with the sequence : 5'-GGCCAGTGAATTGTAATACGACTCACTATAGGGAGGCGGTTTTTTTTTTTTTTTTTTTTTTTT-3'. The mixture was incubated for 10 min at 70oC and chilled on ice. On ice, 4 ul of 5x first-strand buffer, 2 ul 0.1 M DTT, 1 ul of 10 mM dNTP mix and 1 ul Superscript™II RNaseH-reverse transcriptase (200 U/ul) were added to the mixture to make a final volume of 20 ul. The mixture was incubated for 1 hr at 37oC. Second-strand cDNA was synthesized in a volume of 150 ul, containing 92 ul nuclease-free water, 30 ul of 5x second-strand buffer, 3 ul of 10 mM dNTP mix, 4 ul of Escherichia coli DNA polymerase I (10 U/ìl) and 1 ul of RNase H (2 U/ul) for 2 hr at 16oC. The cDNA was purified using a Qiagen QIAquick purification kit, and completely dried down using a Speed-Vac concentrator (45oC) for 2 hr. The dried product was resuspended in IVT reaction mix containing 3.0 ul of nuclease-free water, 4.0 ul 10x reaction buffer, 4.0 ul 75 mM ATP, 4.0 ul 75 mM GTP, 3.0 ul 75 mM CTP, 3.0 ul 75 mM UTP, 7.5 ul 10 mM Biotin 11-CTP, 7.5 ul 10 mM Biotin 11-UTP and 4.0 ul enzyme mix. The reaction mix was incubated for 14 hr at 37oC using an MJ Research 96-well PTC-200 Thermal Cycler (MJ Research, Waltham, MA), before the cRNA was purified using a Qiagen RNeasy® kit. The resulting cRNA yield was quantified using the 96-well ìQuan Universal Microplate Spectrophotometer Model MQX200 (BIO-TEK Instruments Inc., Winooski, VT) at a wavelength of 260 nm. Conformance of the cRNA sample to historical size distributions (the bulk of the cRNA product should be between 500 and 3,000 bases in size) was confirmed using the Agilent 2100 BioAnalyzer (Agilent Technologies, Palo Alto, CA). Samples not near the historical norm were reprocessed starting from tissue or RNA.

growth_protocol: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44.  Sprague-Dawley (Crl:CD®(SD)|GS BR) rats (aged 6-8 weeks and weighing 200 - 260 g), were purchased from Charles River Laboratories (Wilmington, MA). They were housed in plastic cages for 1 week for acclimation to the laboratory environment of a ventilated room (temperature, 22oC ±3oC; humidity, 30 - 70%; light/dark cycle, 12 h d-1, 6:00am - 6:00pm) until use. Certified Rodent Diet #5002 (PMI Feeds Inc.) and chlorinated tap water was available ad libitum.

extract_protocol: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44. Following sacrifice, 6 mm disposable biopsy punches (#REF 33-36 Miltex, Inc. Bethpage, NY) were used to obtain tissue samples of approximately 100 mg. Samples were placed in cryogenic tubes and snap frozen. Poly A(+)-RNA from tissue samples was isolated using the MagNA Pure LC robot (Roche, Basel, Switzerland) in combination with the MagNA Pure LC mRNA Isolation kit I and II (Roche, Basel, Switzerland) for cells (see supplemental methods section) and tissues, respectively. Tissue samples were completely homogenized directly from ~100 mg punches stored on dry ice prior to application of lysis buffer to a final concentration of 65 mg tissue per ml of buffer. After complete homogenization, using disposable Omni Tip Disposable Generator Probes (Omni Inc, Warrenton, VA) and before loading of the samples into the 32-well MagNA Pure plate, the samples were drawn up 5-6 times through a 20-gauge needle attached to a 3-ml syringe to ensure any tissue pieces or clumps were removed from the lysate prior to robotic processing. Tissue sample processing was performed in duplicate wells (loading 150 ul of homogenized sample to each well) of the MagNA Pure LC, which is programmed to extract mRNA using the oligo-dT selection method into a final elution volume of 100 ul. Poly A(+) RNA sample concentration was performed manually using a standard ethanol precipitation protocol in the presence of glycogen (50 ug/ml). After precipitation the final purified RNA sample was resuspended in 7 ìl DEPC-H2O and quantified using a Ribogreen high-range assay (Molecular Probes) on the Wallac Victor2 Fluorometer (Perkin-Elmer, Fremont, CA). Additionally, the integrity of each RNA sample was determined, by comparison to historical standards (no gross degradation should be visible as suggested by clear 18S and 28S peaks on top of a hump of complex RNA, with lower amounts of RNA below 18S than under and above the 18S peak), using the Agilent 2100 BioAnalyzer (Agilent Technologies, Palo Alto, CA) in combination with the RNA 6000 Nano Lab Chip kit (Agilent Technologies).

treatment_protocol: See Ganter et al., J Biotechnol. 2005 Sep 29;119(3):219-44.  Compounds were administered via the route of administration (ROA) that corresponds to that by which humans receive the drug. Compounds were typically administered orally (PO) (83%), intravenously (IV) (9.4%), subcutaneously (SC) (5.7%), or intraperitoneally (IP) (2%). If the compound is a toxicant or a biochemical standard, it was administered orally. For oral dosing, the vehicle choice largely depends on the solubility of the compound in water. Water-soluble compounds were administered in water. Insoluble compounds are administered in either corn oil or 0.5% carboxymethylcellulose (CMC) using the best literature recommendation as a guide. IV administered compounds were usually dissolved in saline and SC administered compounds in corn oil. The highest dose the rats receive is the Maximum Tolerated Dose (MTD). The dosing of animals was staggered based on intended harvest order to ensure that sacrifice occurred within 30 minutes of the recorded time point. Dosing frequency was as described in Sample_characteristics for the particular treatment.

tag: Sprague-Dawley

tag: age

value: 6 to 8 weeks

tag: sex

value: male

tag: tissue

value: LIVER

tag: treatment compound

value: ALPHA-NAPHTHOFLAVONE

tag: dose

value: 80 mg/kg

tag: solvent

value: CMC

tag: administration route

value: ORAL GAVAGE

tag: frequency of dosing

value: DAILY

tag: treatment duration

value: 5 days

tag: experiment date


title: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_91days_exp6314_rep1_86673

description:
HybID: 86673
treated sample for experiment (RepID) 6314
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220542: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_91days_exp6314_rep3_86671
Replicate experimental sample: GSM220541: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_91days_exp6314_rep2_86672
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALPHA-NAPHTHOFLAVONE, 80mg/kg, 91 days

value: 91 days


title: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_28days_exp6315_rep3_86668

description:
HybID: 86668
treated sample for experiment (RepID) 6315
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM220534: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_28days_exp6315_rep1_86669
Replicate experimental sample: GSM220535: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_28days_exp6315_rep2_86670
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALPHA-NAPHTHOFLAVONE, 80mg/kg, 28 days

value: 28 days


title: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_5days_exp6319_rep2_86667

description:
HybID: 86667
treated sample for experiment (RepID) 6319
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220537: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_5days_exp6319_rep1_86665
Replicate experimental sample: GSM220539: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_5days_exp6319_rep3_86666
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: Untreated SF126 - repeat 2 - mAdbID:76735

status: Public on Apr 15 2008

city: Bethesda

first: Uma

middle: T

last: Shankavaram

state: MD

address: 9000 Rockville Pike

department: NCI

institute: NIH

description: mAdb experiment ID: 76735

hyb_protocol: Sample Hybridization Protocol Other: The arrays were prehybridized with buffer (5x SSC, 0.1% SDS, 1% BSA) at 42°C for 1 h. Slides were washed in deionized water followed by 2-propanol. Cy5- and Cy3-labeled cDNA samples were mixed with 1 µl of COT1-DNA (10 µg/µl; Invitrogen, Carlsbad, CA), polyadenylate (8–10 µg/µl; Amersham Pharmacia Biotech, Piscataway, NJ), and yeast tRNA (4 µg/µl; Ambion, Austin, TX) for hybridization. The mixed samples were denatured and after the addition of 20 µl of 2x hybridization buffer (50% formamide, 10x SSC, 0.2% SDS) the entire sample was loaded onto the slides for overnight hybridization at 42°C. After hybridization, the hybridized slides were then washed in 2x SSC, 0.1%, 1x SSC, 0.1% SDS, and 0.2x SSC, for 4 min each, followed by a 1-min wash in 0.05x SSC. Slides were then placed in 2-propanol followed by spin drying.

scan_protocol: Creator: GenePix Pro 4.1.1.4 Scanner: GenePix 4000B [100404] ScanPower: 100;; 100 LaserPower: 3.64;; 3.3 Temperature: 29.47

data_processing:
Data Processing Protocol
Calculation Method: Preliminary filtering of raw data was performed using mAdb tools with the following setting: All flagged spots were treated as missing values and the data was subjected to spot quality filter with signal to background ratios >2, a minimum background corrected signal of 250 counts, and 60% of pixels in the spots with an intensity greater than a SD plus background. Further data analysis was carried out using R software package (R Development Core Team, 2005) ( http://www.R-project.org. ) and custom written scripts. Genes with missing values in greater than 70% of arrays were removed from the analysis and the rest of the missing values were imputed using K-means nearest neighbor method. Lowess normalization (Yang, Y.H. et al., Nucleic Acids Res., 2002) was performed on log2 transformed data. The normalized signal intensity was divided by the control channel intensity and the resulting log ratios from duplicate hybridizations were averaged. After the above processing, 6227 probes remained for further analysis. To show replicate sample similarity, and cell grouping based on gene expression patterns, hierarchical clustering was performed using average linkage and Pearson correlation metric.

molecule: total RNA

organism: Homo sapiens

source_name: Universal Human Reference RNA

label_protocol:
Cy5 Sample Labeling Protocol
Other: Three µg of universal reference RNA were labeledand Cy5 by using Stratagene Fairplay-3 microarray labeling kit (Cedar Creek TX).

extract_protocol:
Strategene UHR RNA Extraction
Other: not available

tag: Other

value: Equal quantities of total RNA from each cell line (brain, breast, B-lymphocyte, cervix, liver, liposarcoma, macrophages, skin, testis, Y-lymphocyte) were pooled together.

source_name: Untreated SF126

label_protocol:
Cy3 Sample Labeling Protocol
Other: Three µg of cell line polysome RNA were labeled with Cy3 by using Stratagene Fairplay-3 microarray labeling kit (Cedar Creek TX).

extract_protocol:
Polysomal Extraction Protocol
Other: Polysomes were isolated using sucrose-gradient fractionation basically as described by Galban et al. Cells were grown to 80% confluence in 150-mm2 tissue culture dishes and incubated in 100 µg of cycloheximide/mL for 15 minutes before collection. Cytoplasmic RNA was obtained by lysing cells in 1 mL of polysome buffer [10 mmol/L Tris-HCl (pH 8), 140 mmol/L NaCl, 1.5 mmol/L MgCl2, 0.5% NP40, 10 mmol/L DTT, 100 µg/mL cycloheximide, 500 µg/mL heparin, 1 mmol/L phenylmethanesulfonyl fluoride, and 500 units/mL RNasin (Promega, Madison, WI)]. After 10 minutes on ice, lysates were centrifuged (10,000 x g for 10 minutes), and the resulting cytosolic supernatant was layered onto a 10% to 50% sucrose gradient. Gradients were then centrifuged at 35,000 x g for 3 hours at 4°C and 1-mL fractions collected using an ISCO Density Gradient Fractionation System (ISCO, Lincoln, NE) with continuous monitoring based on A254. The RNA in each fraction was extracted using TRIZOL and used for Northern analysis, or fractions 5 to 11 (corresponding to polysome-bound RNA) were pooled.

tag: Tissue

value: brain

tag: Cell line

tag: Cell type

value: Glioblastoma; brain/CNS

tag: Disease state

value: Brain cancer


title: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep3_18916

description:
HybID: 18916
treated sample for experiment (RepID) 4325
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM222899: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep2_19160
Replicate experimental sample: GSM222898: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep1_81569
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METRONIDAZOLE, 1500mg/kg, 1 days

value: METRONIDAZOLE

value: WATER

value: 1 days


title: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep3_85569

description:
HybID: 85569
treated sample for experiment (RepID) 6041
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM220531: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep1_85570
Replicate experimental sample: GSM220532: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep2_85571
Matched control sample: GSM204808: LIVER_vehicle_NA_5days_control_NA_85526
Matched control sample: GSM204874: LIVER_vehicle_NA_5days_control_NA_85536
Matched control sample: GSM204676: LIVER_vehicle_NA_1days_control_NA_85576
Matched control sample: GSM204767: LIVER_vehicle_NA_3days_control_NA_85579
Matched control sample: GSM204829: LIVER_vehicle_NA_5days_control_NA_85582
Matched control sample: GSM204702: LIVER_vehicle_NA_1days_control_NA_85602
Matched control sample: GSM204653: LIVER_vehicle_NA_1days_control_NA_85604
Matched control sample: GSM204749: LIVER_vehicle_NA_3days_control_NA_85605
Matched control sample: GSM204788: LIVER_vehicle_NA_3days_control_NA_85607
Matched control sample: GSM204841: LIVER_vehicle_NA_5days_control_NA_85609
Matched control sample: GSM204668: LIVER_vehicle_NA_1days_control_NA_85835
Matched control sample: GSM204709: LIVER_vehicle_NA_1days_control_NA_85837
Matched control sample: GSM204734: LIVER_vehicle_NA_3days_control_NA_85839
Matched control sample: GSM204822: LIVER_vehicle_NA_5days_control_NA_85841
Matched control sample: GSM204864: LIVER_vehicle_NA_5days_control_NA_85843
Matched control sample: GSM204848: LIVER_vehicle_NA_5days_control_NA_85885
Matched control sample: GSM204605: LIVER_vehicle_NA_.25days_control_NA_85890
Matched control sample: GSM204628: LIVER_vehicle_NA_.25days_control_NA_85892
Matched control sample: GSM204710: LIVER_vehicle_NA_1days_control_NA_85897
Matched control sample: GSM204646: LIVER_vehicle_NA_1days_control_NA_85899
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALLYL ALCOHOL, 32mg/kg, 3 days

value: 6 to 8 weeks

value: male

value: ALLYL ALCOHOL

value: 32 mg/kg

value: SALINE

value: INTRAPERITONEAL

value: 3 days


title: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep1_81569

description:
HybID: 81569
treated sample for experiment (RepID) 4325
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM222900: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep3_18916
Replicate experimental sample: GSM222899: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep2_19160
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: LIVER

value: ORAL GAVAGE

value: DAILY


title: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep2_85571

description:
HybID: 85571
treated sample for experiment (RepID) 6041
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220533: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep3_85569
Replicate experimental sample: GSM220531: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep1_85570
Matched control sample: GSM204808: LIVER_vehicle_NA_5days_control_NA_85526
Matched control sample: GSM204874: LIVER_vehicle_NA_5days_control_NA_85536
Matched control sample: GSM204676: LIVER_vehicle_NA_1days_control_NA_85576
Matched control sample: GSM204767: LIVER_vehicle_NA_3days_control_NA_85579
Matched control sample: GSM204829: LIVER_vehicle_NA_5days_control_NA_85582
Matched control sample: GSM204702: LIVER_vehicle_NA_1days_control_NA_85602
Matched control sample: GSM204653: LIVER_vehicle_NA_1days_control_NA_85604
Matched control sample: GSM204749: LIVER_vehicle_NA_3days_control_NA_85605
Matched control sample: GSM204788: LIVER_vehicle_NA_3days_control_NA_85607
Matched control sample: GSM204841: LIVER_vehicle_NA_5days_control_NA_85609
Matched control sample: GSM204668: LIVER_vehicle_NA_1days_control_NA_85835
Matched control sample: GSM204709: LIVER_vehicle_NA_1days_control_NA_85837
Matched control sample: GSM204734: LIVER_vehicle_NA_3days_control_NA_85839
Matched control sample: GSM204822: LIVER_vehicle_NA_5days_control_NA_85841
Matched control sample: GSM204864: LIVER_vehicle_NA_5days_control_NA_85843
Matched control sample: GSM204848: LIVER_vehicle_NA_5days_control_NA_85885
Matched control sample: GSM204605: LIVER_vehicle_NA_.25days_control_NA_85890
Matched control sample: GSM204628: LIVER_vehicle_NA_.25days_control_NA_85892
Matched control sample: GSM204710: LIVER_vehicle_NA_1days_control_NA_85897
Matched control sample: GSM204646: LIVER_vehicle_NA_1days_control_NA_85899
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METRONIDAZOLE_50mg/kg_.25days_exp4292_rep2_18912

description:
HybID: 18912
treated sample for experiment (RepID) 4292
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222905: LIVER_METRONIDAZOLE_50mg/kg_.25days_exp4292_rep3_18913
Replicate experimental sample: GSM222903: LIVER_METRONIDAZOLE_50mg/kg_.25days_exp4292_rep1_18989
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METRONIDAZOLE, 50mg/kg, .25 days

value: 50 mg/kg

value: .25 days


title: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_28days_exp6315_rep1_86669

description:
HybID: 86669
treated sample for experiment (RepID) 6315
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220536: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_28days_exp6315_rep3_86668
Replicate experimental sample: GSM220535: LIVER_ALPHA-NAPHTHOFLAVONE_80mg/kg_28days_exp6315_rep2_86670
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: ALPHA-NAPHTHOFLAVONE

value: 80 mg/kg

value: CMC

value: 28 days


title: LIVER_METRONIDAZOLE_1500mg/kg_3days_exp4477_rep2_18920

description:
HybID: 18920
treated sample for experiment (RepID) 4477
replicate 2 of 2
Experimental sample
Replicate experimental sample: GSM222901: LIVER_METRONIDAZOLE_1500mg/kg_3days_exp4477_rep1_18919
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: METRONIDAZOLE

value: WATER


title: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep3_19629

description:
HybID: 19629
treated sample for experiment (RepID) 4496
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM222896: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep2_19982
Replicate experimental sample: GSM222895: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep1_81626
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METHYL SALICYLATE, 444mg/kg, 5 days

value: 6 to 8 weeks

value: male

value: METHYL SALICYLATE

value: 444 mg/kg

value: CORN OIL

value: 5 days


title: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep2_19160

description:
HybID: 19160
treated sample for experiment (RepID) 4325
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222900: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep3_18916
Replicate experimental sample: GSM222898: LIVER_METRONIDAZOLE_1500mg/kg_1days_exp4325_rep1_81569
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: LIVER

value: 1 days


title: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep2_19982

description:
HybID: 19982
treated sample for experiment (RepID) 4496
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222897: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep3_19629
Replicate experimental sample: GSM222895: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep1_81626
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: ORAL GAVAGE

value: DAILY


title: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep2_85568

description:
HybID: 85568
treated sample for experiment (RepID) 6029
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220530: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep3_85566
Replicate experimental sample: GSM220528: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep1_85567
Matched control sample: GSM204808: LIVER_vehicle_NA_5days_control_NA_85526
Matched control sample: GSM204874: LIVER_vehicle_NA_5days_control_NA_85536
Matched control sample: GSM204676: LIVER_vehicle_NA_1days_control_NA_85576
Matched control sample: GSM204767: LIVER_vehicle_NA_3days_control_NA_85579
Matched control sample: GSM204829: LIVER_vehicle_NA_5days_control_NA_85582
Matched control sample: GSM204702: LIVER_vehicle_NA_1days_control_NA_85602
Matched control sample: GSM204653: LIVER_vehicle_NA_1days_control_NA_85604
Matched control sample: GSM204749: LIVER_vehicle_NA_3days_control_NA_85605
Matched control sample: GSM204788: LIVER_vehicle_NA_3days_control_NA_85607
Matched control sample: GSM204841: LIVER_vehicle_NA_5days_control_NA_85609
Matched control sample: GSM204668: LIVER_vehicle_NA_1days_control_NA_85835
Matched control sample: GSM204709: LIVER_vehicle_NA_1days_control_NA_85837
Matched control sample: GSM204734: LIVER_vehicle_NA_3days_control_NA_85839
Matched control sample: GSM204822: LIVER_vehicle_NA_5days_control_NA_85841
Matched control sample: GSM204864: LIVER_vehicle_NA_5days_control_NA_85843
Matched control sample: GSM204848: LIVER_vehicle_NA_5days_control_NA_85885
Matched control sample: GSM204605: LIVER_vehicle_NA_.25days_control_NA_85890
Matched control sample: GSM204628: LIVER_vehicle_NA_.25days_control_NA_85892
Matched control sample: GSM204710: LIVER_vehicle_NA_1days_control_NA_85897
Matched control sample: GSM204646: LIVER_vehicle_NA_1days_control_NA_85899
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALLYL ALCOHOL, 32mg/kg, 1 days

value: ALLYL ALCOHOL

value: 32 mg/kg

value: SALINE

value: INTRAPERITONEAL


title: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep1_85570

description:
HybID: 85570
treated sample for experiment (RepID) 6041
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220533: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep3_85569
Replicate experimental sample: GSM220532: LIVER_ALLYL_ALCOHOL_32mg/kg_3days_exp6041_rep2_85571
Matched control sample: GSM204808: LIVER_vehicle_NA_5days_control_NA_85526
Matched control sample: GSM204874: LIVER_vehicle_NA_5days_control_NA_85536
Matched control sample: GSM204676: LIVER_vehicle_NA_1days_control_NA_85576
Matched control sample: GSM204767: LIVER_vehicle_NA_3days_control_NA_85579
Matched control sample: GSM204829: LIVER_vehicle_NA_5days_control_NA_85582
Matched control sample: GSM204702: LIVER_vehicle_NA_1days_control_NA_85602
Matched control sample: GSM204653: LIVER_vehicle_NA_1days_control_NA_85604
Matched control sample: GSM204749: LIVER_vehicle_NA_3days_control_NA_85605
Matched control sample: GSM204788: LIVER_vehicle_NA_3days_control_NA_85607
Matched control sample: GSM204841: LIVER_vehicle_NA_5days_control_NA_85609
Matched control sample: GSM204668: LIVER_vehicle_NA_1days_control_NA_85835
Matched control sample: GSM204709: LIVER_vehicle_NA_1days_control_NA_85837
Matched control sample: GSM204734: LIVER_vehicle_NA_3days_control_NA_85839
Matched control sample: GSM204822: LIVER_vehicle_NA_5days_control_NA_85841
Matched control sample: GSM204864: LIVER_vehicle_NA_5days_control_NA_85843
Matched control sample: GSM204848: LIVER_vehicle_NA_5days_control_NA_85885
Matched control sample: GSM204605: LIVER_vehicle_NA_.25days_control_NA_85890
Matched control sample: GSM204628: LIVER_vehicle_NA_.25days_control_NA_85892
Matched control sample: GSM204710: LIVER_vehicle_NA_1days_control_NA_85897
Matched control sample: GSM204646: LIVER_vehicle_NA_1days_control_NA_85899
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: 3 days


title: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep1_85567

description:
HybID: 85567
treated sample for experiment (RepID) 6029
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220530: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep3_85566
Replicate experimental sample: GSM220529: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep2_85568
Matched control sample: GSM204808: LIVER_vehicle_NA_5days_control_NA_85526
Matched control sample: GSM204874: LIVER_vehicle_NA_5days_control_NA_85536
Matched control sample: GSM204676: LIVER_vehicle_NA_1days_control_NA_85576
Matched control sample: GSM204767: LIVER_vehicle_NA_3days_control_NA_85579
Matched control sample: GSM204829: LIVER_vehicle_NA_5days_control_NA_85582
Matched control sample: GSM204702: LIVER_vehicle_NA_1days_control_NA_85602
Matched control sample: GSM204653: LIVER_vehicle_NA_1days_control_NA_85604
Matched control sample: GSM204749: LIVER_vehicle_NA_3days_control_NA_85605
Matched control sample: GSM204788: LIVER_vehicle_NA_3days_control_NA_85607
Matched control sample: GSM204841: LIVER_vehicle_NA_5days_control_NA_85609
Matched control sample: GSM204668: LIVER_vehicle_NA_1days_control_NA_85835
Matched control sample: GSM204709: LIVER_vehicle_NA_1days_control_NA_85837
Matched control sample: GSM204734: LIVER_vehicle_NA_3days_control_NA_85839
Matched control sample: GSM204822: LIVER_vehicle_NA_5days_control_NA_85841
Matched control sample: GSM204864: LIVER_vehicle_NA_5days_control_NA_85843
Matched control sample: GSM204848: LIVER_vehicle_NA_5days_control_NA_85885
Matched control sample: GSM204605: LIVER_vehicle_NA_.25days_control_NA_85890
Matched control sample: GSM204628: LIVER_vehicle_NA_.25days_control_NA_85892
Matched control sample: GSM204710: LIVER_vehicle_NA_1days_control_NA_85897
Matched control sample: GSM204646: LIVER_vehicle_NA_1days_control_NA_85899
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep2_19628

description:
HybID: 19628
treated sample for experiment (RepID) 4500
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222894: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep3_19684
Replicate experimental sample: GSM222892: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep1_19685
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METHYL SALICYLATE, 444mg/kg, 3 days


title: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep1_81626

description:
HybID: 81626
treated sample for experiment (RepID) 4496
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM222897: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep3_19629
Replicate experimental sample: GSM222896: LIVER_METHYL_SALICYLATE_444mg/kg_5days_exp4496_rep2_19982
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep3_19684

description:
HybID: 19684
treated sample for experiment (RepID) 4500
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM222893: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep2_19628
Replicate experimental sample: GSM222892: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep1_19685
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep3_85566

description:
HybID: 85566
treated sample for experiment (RepID) 6029
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM220528: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep1_85567
Replicate experimental sample: GSM220529: LIVER_ALLYL_ALCOHOL_32mg/kg_1days_exp6029_rep2_85568
Matched control sample: GSM204808: LIVER_vehicle_NA_5days_control_NA_85526
Matched control sample: GSM204874: LIVER_vehicle_NA_5days_control_NA_85536
Matched control sample: GSM204676: LIVER_vehicle_NA_1days_control_NA_85576
Matched control sample: GSM204767: LIVER_vehicle_NA_3days_control_NA_85579
Matched control sample: GSM204829: LIVER_vehicle_NA_5days_control_NA_85582
Matched control sample: GSM204702: LIVER_vehicle_NA_1days_control_NA_85602
Matched control sample: GSM204653: LIVER_vehicle_NA_1days_control_NA_85604
Matched control sample: GSM204749: LIVER_vehicle_NA_3days_control_NA_85605
Matched control sample: GSM204788: LIVER_vehicle_NA_3days_control_NA_85607
Matched control sample: GSM204841: LIVER_vehicle_NA_5days_control_NA_85609
Matched control sample: GSM204668: LIVER_vehicle_NA_1days_control_NA_85835
Matched control sample: GSM204709: LIVER_vehicle_NA_1days_control_NA_85837
Matched control sample: GSM204734: LIVER_vehicle_NA_3days_control_NA_85839
Matched control sample: GSM204822: LIVER_vehicle_NA_5days_control_NA_85841
Matched control sample: GSM204864: LIVER_vehicle_NA_5days_control_NA_85843
Matched control sample: GSM204848: LIVER_vehicle_NA_5days_control_NA_85885
Matched control sample: GSM204605: LIVER_vehicle_NA_.25days_control_NA_85890
Matched control sample: GSM204628: LIVER_vehicle_NA_.25days_control_NA_85892
Matched control sample: GSM204710: LIVER_vehicle_NA_1days_control_NA_85897
Matched control sample: GSM204646: LIVER_vehicle_NA_1days_control_NA_85899
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep3_88736

description:
HybID: 88736
treated sample for experiment (RepID) 6937
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM220510: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep1_88712
Replicate experimental sample: GSM220511: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep2_88727
Matched control sample: GSM204686: LIVER_vehicle_NA_1days_control_NA_88722
Matched control sample: GSM204845: LIVER_vehicle_NA_5days_control_NA_88763
Matched control sample: GSM204696: LIVER_vehicle_NA_1days_control_NA_89140
Matched control sample: GSM204651: LIVER_vehicle_NA_1days_control_NA_89142
Matched control sample: GSM204800: LIVER_vehicle_NA_4days_control_NA_89144
Matched control sample: GSM204797: LIVER_vehicle_NA_4days_control_NA_89146
Matched control sample: GSM204635: LIVER_vehicle_NA_0days_control_NA_89148
Matched control sample: GSM204634: LIVER_vehicle_NA_0days_control_NA_89150
Matched control sample: GSM204722: LIVER_vehicle_NA_30days_control_NA_89231
Matched control sample: GSM204798: LIVER_vehicle_NA_4days_control_NA_89446
Matched control sample: GSM204875: LIVER_vehicle_NA_6days_control_NA_89484
Matched control sample: GSM204876: LIVER_vehicle_NA_6days_control_NA_89516
Matched control sample: GSM204799: LIVER_vehicle_NA_4days_control_NA_89522
Matched control sample: GSM204707: LIVER_vehicle_NA_1days_control_NA_89555
Matched control sample: GSM204670: LIVER_vehicle_NA_1days_control_NA_89557
Matched control sample: GSM204667: LIVER_vehicle_NA_1days_control_NA_89706
Matched control sample: GSM204769: LIVER_vehicle_NA_3days_control_NA_89709
Matched control sample: GSM204824: LIVER_vehicle_NA_5days_control_NA_89713
Matched control sample: GSM204879: LIVER_vehicle_NA_7days_control_NA_89818
Matched control sample: GSM204764: LIVER_vehicle_NA_3days_control_NA_89852
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALLYL ALCOHOL, 16mg/kg, 5 days

value: 16 mg/kg


title: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep3_19621

description:
HybID: 19621
treated sample for experiment (RepID) 4466
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM222890: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep2_19622
Replicate experimental sample: GSM222889: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep1_19627
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METHYL SALICYLATE, 444mg/kg, 1 days


title: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep2_88727

description:
HybID: 88727
treated sample for experiment (RepID) 6937
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220510: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep1_88712
Replicate experimental sample: GSM220512: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep3_88736
Matched control sample: GSM204686: LIVER_vehicle_NA_1days_control_NA_88722
Matched control sample: GSM204845: LIVER_vehicle_NA_5days_control_NA_88763
Matched control sample: GSM204696: LIVER_vehicle_NA_1days_control_NA_89140
Matched control sample: GSM204651: LIVER_vehicle_NA_1days_control_NA_89142
Matched control sample: GSM204800: LIVER_vehicle_NA_4days_control_NA_89144
Matched control sample: GSM204797: LIVER_vehicle_NA_4days_control_NA_89146
Matched control sample: GSM204635: LIVER_vehicle_NA_0days_control_NA_89148
Matched control sample: GSM204634: LIVER_vehicle_NA_0days_control_NA_89150
Matched control sample: GSM204722: LIVER_vehicle_NA_30days_control_NA_89231
Matched control sample: GSM204798: LIVER_vehicle_NA_4days_control_NA_89446
Matched control sample: GSM204875: LIVER_vehicle_NA_6days_control_NA_89484
Matched control sample: GSM204876: LIVER_vehicle_NA_6days_control_NA_89516
Matched control sample: GSM204799: LIVER_vehicle_NA_4days_control_NA_89522
Matched control sample: GSM204707: LIVER_vehicle_NA_1days_control_NA_89555
Matched control sample: GSM204670: LIVER_vehicle_NA_1days_control_NA_89557
Matched control sample: GSM204667: LIVER_vehicle_NA_1days_control_NA_89706
Matched control sample: GSM204769: LIVER_vehicle_NA_3days_control_NA_89709
Matched control sample: GSM204824: LIVER_vehicle_NA_5days_control_NA_89713
Matched control sample: GSM204879: LIVER_vehicle_NA_7days_control_NA_89818
Matched control sample: GSM204764: LIVER_vehicle_NA_3days_control_NA_89852
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep1_19627

description:
HybID: 19627
treated sample for experiment (RepID) 4466
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM222891: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep3_19621
Replicate experimental sample: GSM222890: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep2_19622
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep2_19622

description:
HybID: 19622
treated sample for experiment (RepID) 4466
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222891: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep3_19621
Replicate experimental sample: GSM222889: LIVER_METHYL_SALICYLATE_444mg/kg_1days_exp4466_rep1_19627
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep3_19625

description:
HybID: 19625
treated sample for experiment (RepID) 4465
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM222887: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep2_19626
Replicate experimental sample: GSM222886: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep1_19683
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METHYL SALICYLATE, 444mg/kg, .25 days

value: .25 days


title: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep1_88712

description:
HybID: 88712
treated sample for experiment (RepID) 6937
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220511: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep2_88727
Replicate experimental sample: GSM220512: LIVER_ALLYL_ALCOHOL_16mg/kg_5days_exp6937_rep3_88736
Matched control sample: GSM204686: LIVER_vehicle_NA_1days_control_NA_88722
Matched control sample: GSM204845: LIVER_vehicle_NA_5days_control_NA_88763
Matched control sample: GSM204696: LIVER_vehicle_NA_1days_control_NA_89140
Matched control sample: GSM204651: LIVER_vehicle_NA_1days_control_NA_89142
Matched control sample: GSM204800: LIVER_vehicle_NA_4days_control_NA_89144
Matched control sample: GSM204797: LIVER_vehicle_NA_4days_control_NA_89146
Matched control sample: GSM204635: LIVER_vehicle_NA_0days_control_NA_89148
Matched control sample: GSM204634: LIVER_vehicle_NA_0days_control_NA_89150
Matched control sample: GSM204722: LIVER_vehicle_NA_30days_control_NA_89231
Matched control sample: GSM204798: LIVER_vehicle_NA_4days_control_NA_89446
Matched control sample: GSM204875: LIVER_vehicle_NA_6days_control_NA_89484
Matched control sample: GSM204876: LIVER_vehicle_NA_6days_control_NA_89516
Matched control sample: GSM204799: LIVER_vehicle_NA_4days_control_NA_89522
Matched control sample: GSM204707: LIVER_vehicle_NA_1days_control_NA_89555
Matched control sample: GSM204670: LIVER_vehicle_NA_1days_control_NA_89557
Matched control sample: GSM204667: LIVER_vehicle_NA_1days_control_NA_89706
Matched control sample: GSM204769: LIVER_vehicle_NA_3days_control_NA_89709
Matched control sample: GSM204824: LIVER_vehicle_NA_5days_control_NA_89713
Matched control sample: GSM204879: LIVER_vehicle_NA_7days_control_NA_89818
Matched control sample: GSM204764: LIVER_vehicle_NA_3days_control_NA_89852
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: 6 to 8 weeks


title: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep3_88717

description:
HybID: 88717
treated sample for experiment (RepID) 6927
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM220505: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep2_88728
Replicate experimental sample: GSM220504: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep1_88765
Matched control sample: GSM204686: LIVER_vehicle_NA_1days_control_NA_88722
Matched control sample: GSM204845: LIVER_vehicle_NA_5days_control_NA_88763
Matched control sample: GSM204696: LIVER_vehicle_NA_1days_control_NA_89140
Matched control sample: GSM204651: LIVER_vehicle_NA_1days_control_NA_89142
Matched control sample: GSM204800: LIVER_vehicle_NA_4days_control_NA_89144
Matched control sample: GSM204797: LIVER_vehicle_NA_4days_control_NA_89146
Matched control sample: GSM204635: LIVER_vehicle_NA_0days_control_NA_89148
Matched control sample: GSM204634: LIVER_vehicle_NA_0days_control_NA_89150
Matched control sample: GSM204722: LIVER_vehicle_NA_30days_control_NA_89231
Matched control sample: GSM204798: LIVER_vehicle_NA_4days_control_NA_89446
Matched control sample: GSM204875: LIVER_vehicle_NA_6days_control_NA_89484
Matched control sample: GSM204876: LIVER_vehicle_NA_6days_control_NA_89516
Matched control sample: GSM204799: LIVER_vehicle_NA_4days_control_NA_89522
Matched control sample: GSM204707: LIVER_vehicle_NA_1days_control_NA_89555
Matched control sample: GSM204670: LIVER_vehicle_NA_1days_control_NA_89557
Matched control sample: GSM204667: LIVER_vehicle_NA_1days_control_NA_89706
Matched control sample: GSM204769: LIVER_vehicle_NA_3days_control_NA_89709
Matched control sample: GSM204824: LIVER_vehicle_NA_5days_control_NA_89713
Matched control sample: GSM204879: LIVER_vehicle_NA_7days_control_NA_89818
Matched control sample: GSM204764: LIVER_vehicle_NA_3days_control_NA_89852
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALLYL ALCOHOL, 16mg/kg, 1 days

value: male


title: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep2_19626

description:
HybID: 19626
treated sample for experiment (RepID) 4465
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222888: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep3_19625
Replicate experimental sample: GSM222886: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep1_19683
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: METHYL SALICYLATE


title: LIVER_ALFACALCIDOL_.043mg/kg_1days_exp6295_rep1_86608

description:
HybID: 86608
treated sample for experiment (RepID) 6295
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220493: LIVER_ALFACALCIDOL_.043mg/kg_1days_exp6295_rep2_86607
Replicate experimental sample: GSM220494: LIVER_ALFACALCIDOL_.043mg/kg_1days_exp6295_rep3_86609
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALFACALCIDOL, .043mg/kg, 1 days

value: ALFACALCIDOL

value: CMC


title: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep1_88765

description:
HybID: 88765
treated sample for experiment (RepID) 6927
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220506: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep3_88717
Replicate experimental sample: GSM220505: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep2_88728
Matched control sample: GSM204686: LIVER_vehicle_NA_1days_control_NA_88722
Matched control sample: GSM204845: LIVER_vehicle_NA_5days_control_NA_88763
Matched control sample: GSM204696: LIVER_vehicle_NA_1days_control_NA_89140
Matched control sample: GSM204651: LIVER_vehicle_NA_1days_control_NA_89142
Matched control sample: GSM204800: LIVER_vehicle_NA_4days_control_NA_89144
Matched control sample: GSM204797: LIVER_vehicle_NA_4days_control_NA_89146
Matched control sample: GSM204635: LIVER_vehicle_NA_0days_control_NA_89148
Matched control sample: GSM204634: LIVER_vehicle_NA_0days_control_NA_89150
Matched control sample: GSM204722: LIVER_vehicle_NA_30days_control_NA_89231
Matched control sample: GSM204798: LIVER_vehicle_NA_4days_control_NA_89446
Matched control sample: GSM204875: LIVER_vehicle_NA_6days_control_NA_89484
Matched control sample: GSM204876: LIVER_vehicle_NA_6days_control_NA_89516
Matched control sample: GSM204799: LIVER_vehicle_NA_4days_control_NA_89522
Matched control sample: GSM204707: LIVER_vehicle_NA_1days_control_NA_89555
Matched control sample: GSM204670: LIVER_vehicle_NA_1days_control_NA_89557
Matched control sample: GSM204667: LIVER_vehicle_NA_1days_control_NA_89706
Matched control sample: GSM204769: LIVER_vehicle_NA_3days_control_NA_89709
Matched control sample: GSM204824: LIVER_vehicle_NA_5days_control_NA_89713
Matched control sample: GSM204879: LIVER_vehicle_NA_7days_control_NA_89818
Matched control sample: GSM204764: LIVER_vehicle_NA_3days_control_NA_89852
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep3_86610

description:
HybID: 86610
treated sample for experiment (RepID) 6300
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM220495: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep1_86611
Replicate experimental sample: GSM220496: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep2_86612
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, ALFACALCIDOL, .043mg/kg, 3 days


title: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep2_86612

description:
HybID: 86612
treated sample for experiment (RepID) 6300
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220497: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep3_86610
Replicate experimental sample: GSM220495: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep1_86611
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHOCARBAMOL_1125mg/kg_5days_exp4792_rep2_80778

description:
HybID: 80778
treated sample for experiment (RepID) 4792
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM222850: LIVER_METHOCARBAMOL_1125mg/kg_5days_exp4792_rep3_80776
Replicate experimental sample: GSM222848: LIVER_METHOCARBAMOL_1125mg/kg_5days_exp4792_rep1_80777
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METHOCARBAMOL, 1125mg/kg, 5 days

value: METHOCARBAMOL

value: 5 days


title: LIVER_ALFACALCIDOL_.043mg/kg_1days_exp6295_rep2_86607

description:
HybID: 86607
treated sample for experiment (RepID) 6295
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220492: LIVER_ALFACALCIDOL_.043mg/kg_1days_exp6295_rep1_86608
Replicate experimental sample: GSM220494: LIVER_ALFACALCIDOL_.043mg/kg_1days_exp6295_rep3_86609
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: LIVER

value: 1 days


title: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep2_88728

description:
HybID: 88728
treated sample for experiment (RepID) 6927
replicate 2 of 3
Experimental sample
Replicate experimental sample: GSM220506: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep3_88717
Replicate experimental sample: GSM220504: LIVER_ALLYL_ALCOHOL_16mg/kg_1days_exp6927_rep1_88765
Matched control sample: GSM204686: LIVER_vehicle_NA_1days_control_NA_88722
Matched control sample: GSM204845: LIVER_vehicle_NA_5days_control_NA_88763
Matched control sample: GSM204696: LIVER_vehicle_NA_1days_control_NA_89140
Matched control sample: GSM204651: LIVER_vehicle_NA_1days_control_NA_89142
Matched control sample: GSM204800: LIVER_vehicle_NA_4days_control_NA_89144
Matched control sample: GSM204797: LIVER_vehicle_NA_4days_control_NA_89146
Matched control sample: GSM204635: LIVER_vehicle_NA_0days_control_NA_89148
Matched control sample: GSM204634: LIVER_vehicle_NA_0days_control_NA_89150
Matched control sample: GSM204722: LIVER_vehicle_NA_30days_control_NA_89231
Matched control sample: GSM204798: LIVER_vehicle_NA_4days_control_NA_89446
Matched control sample: GSM204875: LIVER_vehicle_NA_6days_control_NA_89484
Matched control sample: GSM204876: LIVER_vehicle_NA_6days_control_NA_89516
Matched control sample: GSM204799: LIVER_vehicle_NA_4days_control_NA_89522
Matched control sample: GSM204707: LIVER_vehicle_NA_1days_control_NA_89555
Matched control sample: GSM204670: LIVER_vehicle_NA_1days_control_NA_89557
Matched control sample: GSM204667: LIVER_vehicle_NA_1days_control_NA_89706
Matched control sample: GSM204769: LIVER_vehicle_NA_3days_control_NA_89709
Matched control sample: GSM204824: LIVER_vehicle_NA_5days_control_NA_89713
Matched control sample: GSM204879: LIVER_vehicle_NA_7days_control_NA_89818
Matched control sample: GSM204764: LIVER_vehicle_NA_3days_control_NA_89852
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: DAILY


title: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep1_86611

description:
HybID: 86611
treated sample for experiment (RepID) 6300
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM220497: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep3_86610
Replicate experimental sample: GSM220496: LIVER_ALFACALCIDOL_.043mg/kg_3days_exp6300_rep2_86612
Matched control sample: GSM204831: LIVER_vehicle_NA_5days_control_NA_86647
Matched control sample: GSM204857: LIVER_vehicle_NA_5days_control_NA_86649
Matched control sample: GSM204721: LIVER_vehicle_NA_28days_control_NA_86650
Matched control sample: GSM204720: LIVER_vehicle_NA_28days_control_NA_86651
Matched control sample: GSM204880: LIVER_vehicle_NA_91days_control_NA_86653
Matched control sample: GSM204881: LIVER_vehicle_NA_91days_control_NA_86655
Matched control sample: GSM204701: LIVER_vehicle_NA_1days_control_NA_86693
Matched control sample: GSM204636: LIVER_vehicle_NA_1days_control_NA_86694
Matched control sample: GSM204747: LIVER_vehicle_NA_3days_control_NA_86714
Matched control sample: GSM204820: LIVER_vehicle_NA_5days_control_NA_86744
Matched control sample: GSM204664: LIVER_vehicle_NA_1days_control_NA_86757
Matched control sample: GSM204862: LIVER_vehicle_NA_5days_control_NA_86795
Matched control sample: GSM204783: LIVER_vehicle_NA_3days_control_NA_86796
Matched control sample: GSM204641: LIVER_vehicle_NA_1days_control_NA_86828
Matched control sample: GSM204814: LIVER_vehicle_NA_5days_control_NA_86831
Matched control sample: GSM204600: LIVER_vehicle_NA_.25days_control_NA_86882
Matched control sample: GSM204777: LIVER_vehicle_NA_3days_control_NA_86900
Matched control sample: GSM204627: LIVER_vehicle_NA_.25days_control_NA_86918
Matched control sample: GSM204748: LIVER_vehicle_NA_3days_control_NA_86923
Matched control sample: GSM204695: LIVER_vehicle_NA_1days_control_NA_87048
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: ORAL GAVAGE


title: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep1_19685

description:
HybID: 19685
treated sample for experiment (RepID) 4500
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM222893: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep2_19628
Replicate experimental sample: GSM222894: LIVER_METHYL_SALICYLATE_444mg/kg_3days_exp4500_rep3_19684
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

value: 444 mg/kg

value: CORN OIL


title: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep1_19683

description:
HybID: 19683
treated sample for experiment (RepID) 4465
replicate 1 of 3
Experimental sample
Replicate experimental sample: GSM222888: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep3_19625
Replicate experimental sample: GSM222887: LIVER_METHYL_SALICYLATE_444mg/kg_.25days_exp4465_rep2_19626
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf


title: LIVER_METHOCARBAMOL_1125mg/kg_3days_exp4750_rep1_80680

description:
HybID: 80680
treated sample for experiment (RepID) 4750
replicate 1 of 2
Experimental sample
Replicate experimental sample: GSM222847: LIVER_METHOCARBAMOL_1125mg/kg_3days_exp4750_rep2_80775
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf

source_name: LIVER, METHOCARBAMOL, 1125mg/kg, 3 days


title: LIVER_METHOCARBAMOL_1125mg/kg_5days_exp4792_rep3_80776

description:
HybID: 80776
treated sample for experiment (RepID) 4792
replicate 3 of 3
Experimental sample
Replicate experimental sample: GSM222848: LIVER_METHOCARBAMOL_1125mg/kg_5days_exp4792_rep1_80777
Replicate experimental sample: GSM222849: LIVER_METHOCARBAMOL_1125mg/kg_5days_exp4792_rep2_80778
Matched control sample: GSM204608: LIVER_vehicle_NA_.25days_control_NA_18857
Matched control sample: GSM204708: LIVER_vehicle_NA_1days_control_NA_18859
Matched control sample: GSM204742: LIVER_vehicle_NA_3days_control_NA_18863
Matched control sample: GSM204602: LIVER_vehicle_NA_.25days_control_NA_18865
Matched control sample: GSM204691: LIVER_vehicle_NA_1days_control_NA_18868
Matched control sample: GSM204760: LIVER_vehicle_NA_3days_control_NA_18872
Matched control sample: GSM204663: LIVER_vehicle_NA_1days_control_NA_18986
Matched control sample: GSM204604: LIVER_vehicle_NA_.25days_control_NA_19233
Matched control sample: GSM204677: LIVER_vehicle_NA_1days_control_NA_19236
Matched control sample: GSM204771: LIVER_vehicle_NA_3days_control_NA_19238
Matched control sample: GSM204642: LIVER_vehicle_NA_1days_control_NA_80157
Matched control sample: GSM204718: LIVER_vehicle_NA_1days_control_NA_80159
Matched control sample: GSM204621: LIVER_vehicle_NA_.25days_control_NA_80565
Matched control sample: GSM204768: LIVER_vehicle_NA_3days_control_NA_80570
Matched control sample: GSM204868: LIVER_vehicle_NA_5days_control_NA_80573
Matched control sample: GSM204669: LIVER_vehicle_NA_1days_control_NA_80683
Matched control sample: GSM204629: LIVER_vehicle_NA_.25days_control_NA_81664
Matched control sample: GSM204782: LIVER_vehicle_NA_3days_control_NA_81665
Guidelines for commercial use:
http://www.iconixbiosciences.com/guidelineCommUse.pdf