title: Dm_sn_d_27

status: Public on Mar 04 2010

city: Jyvaskyla

first: Maaria

last: Kankare

address: Survontie 9

country: Finland

institute: University of Jyvaskyla

description: In addition to the 101 candidate genes we placed on our chip, we used seven genes, Ef1α48D, eIF-4a Gapdh1, Gapdh2, RpL11, RpL19 and RpL27A, which have been used as control genes in Drosophila whole genome microarrays (GeneChip Drosophila genome 2.0 Array, Affymetrix, 2006). These genes were added on the chip to select the best control genes for microarray validation with qRT-PCR analysis.

hyb_protocol: 600 ng of each cRNA sample was hybridized to Agilent’s 8x15K D. montana custom arrays with Gasket slide at 65˚C overnight (17 h) using Agilent’s Gene Expression Hybridization Kit and washed with Agilent’s Gene Expression Wash Pack and Stabilization and Drying solution

scan_protocol: Arrays were scanned with Agilent Technologies Scanner (model G2505B) and numerical results were extracted with Feature Extraction version 9.5.3.1 using 018413_D_F_20071204 grid, GE1-v5_95_Feb07 protocol and GE1_QCM_Feb07 QC metric set.

data_processing: The microarray data were normalized within the groups and across all samples using the VSN method. The statistical analyses were carried out using Bioconductor related Limma package [10] and the differentially expressed genes in each comparison were selected requiring a strict selection criteria of fold-change > 2.0 and false discovery rate (fdr) < 0.05.

organism: Drosophila montana

source_name: Whole body

label_protocol: 350 ng total RNA of each sample was amplified and Cy3-labeled with Agilent’s Low RNA Input Linear Amplification Kit PLUS (One Color) and processed together with Agilent’s One-Colour RNA Spike-in Kit.

growth_protocol: Female flies for the present study were collected under a light CO2 anaesthesia within one day after their emergence. Samples of young flies (three replicates, each including 13 flies) were transferred straight from the culturing conditions into liquid nitrogen for RNA extractions. The rest of the females were placed in vials (13-15 flies per vial) containing 7 ml of yeast-sucrose-agar medium with 1 mg of yeast sprinkled on top of the medium. The samples of reproducing females were obtained by maintaining the vials in a climate chamber in continuous light (24:0) for two weeks. Samples of diapausing females were maintained by keeping the vials in a climate chamber in a L:D cycle of 16:8 for the same time period.

extract_protocol: Total RNA was extracted from the whole body of 13 individuals per sample, three replicates per sample. Qiagen RNA extraction kit with RNase-Free DNase treatment was used according to the manufacturer's protocols (Qiagen). The RNA was purified using Qiagen RNAeasy purification kit and the concentration and the purity of each sample was measured with NanoDrop ND-1000 spectrofotometer (NanoDrop Technologies, Wilmington, DE, USA).

treatment_protocol: Flies were maintained in vials in the laboratory under diapause-preventing conditions (continuous light, 19°C) since summer 2003.

tag: isofemale line

value: O3F66 from Oulanka, Finland


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-8

status: Public on Apr 28 2009

type: RNA

city: RTP

first: Pierre

middle: Robert

last: Bushel

state: NC

department: Biostatistics and Computational Biology Branch

country: USA

institute: NIEHS

description: 5 mg/kg X 48 hr

hyb_protocol: Equal amounts of Cy3- or Cy5-labeled cRNA were hybridized to the array for 17 hours prior to washing and scanning.

scan_protocol: Pixel intensity data were extracted from scanned images using the Agilent Technologies Scanner and Feature Extraction Software (Agilent Technologies).  See the header of the Agilent data files for more details of the scanning and data acquisition harware and software versions and parameters.

data_processing: log base 2 ratio of Dye Normalized rProcessedSignal to gProcessedSignal

molecule: total RNA

organism: Rattus norvegicus

source_name: 5mg/kg Diquat Dibromide 48hr rat 70 liver

label_protocol: 1 ug of total RNA was amplified and labeled with a fluorescent dye using the Low RNA Input Linear Amplification Labeling kit (Agilent Technologies, Palo Alto, CA, USA) following the manufacturer's protocol.

extract_protocol: RNA was isolated from the flash frozen portion of the left lateral liver lobe using RNeasy Midi columns (Qiagen, Valencia, CA, USA) according to the manufacturer's protocol.

tag: strain

tag: gender

value: male

tag: age

value: 10-12 weeks

tag: tissue

value: Liver

source_name: 0mg/kg Diquat Dibromide 48hr rat liver pool


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-12

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 72 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-11

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 53 liver

source_name: 0mg/kg Diquat Dibromide 24hr rat liver pool


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-9

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 71 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-9

description: 25 mg/kg X 6 hr

source_name: 0mg/kg Diquat Dibromide 6hr rat liver pool

source_name: 25mg/kg Diquat Dibromide 6hr rat 29 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-10

description: 5 mg/kg X 48 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-10

description: 25 mg/kg X 6 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-9

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 52 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-11

description: 25 mg/kg X 6 hr

source_name: 25mg/kg Diquat Dibromide 6hr rat 30 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-8

description: 25 mg/kg X 6 hr

source_name: 25mg/kg Diquat Dibromide 6hr rat 28 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-7

description: 25 mg/kg X 6 hr


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-11

description: 5 mg/kg X 48 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-6

description: 25 mg/kg X 6 hr

source_name: 25mg/kg Diquat Dibromide 6hr rat 27 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-2

description: 25 mg/kg X 6 hr

source_name: 25mg/kg Diquat Dibromide 6hr rat 25 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-3

description: 25 mg/kg X 6 hr

source_name: 25mg/kg Diquat Dibromide 6hr rat 26 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-5

description: 25 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-1

description: 25 mg/kg X 6 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-8

description: 5 mg/kg X 24 hr

source_name: 5mg/kg Diquat Dibromide 24hr rat 39 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-11

description: 20 mg/kg X 6 hr

source_name: 20mg/kg Diquat Dibromide 6hr rat 24 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-10

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 10 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 25 liver-4

description: 25 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-12

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 11 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 76 liver-5

description: 10 mg/kg X 48 hr

source_name: 0mg/kg Diquat Dibromide 48hr rat liver pool

source_name: 10mg/kg Diquat Dibromide 48hr rat 77 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-7

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 70 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-11

description: 5 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-9

description: 20 mg/kg X 6 hr

source_name: 20mg/kg Diquat Dibromide 6hr rat 23 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-6

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 69 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-4

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 68 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-3

description: 5 mg/kg X 48 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-12

description: 20 mg/kg X 6 hr

source_name: 0mg/kg Diquat Dibromide 6hr rat liver pool


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-5

description: 5 mg/kg X 48 hr


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-2

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 67 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 76 liver-3

description: 10 mg/kg X 48 hr

source_name: 10mg/kg Diquat Dibromide 48hr rat 76 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 76 liver-2

description: 10 mg/kg X 48 hr

source_name: 10mg/kg Diquat Dibromide 48hr rat 75 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 76 liver-4

description: 10 mg/kg X 48 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-7

description: 25 mg/kg X 24 hr

source_name: 25mg/kg Diquat Dibromide 24hr rat 60 liver

source_name: 0mg/kg Diquat Dibromide 24hr rat liver pool


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-6

description: 25 mg/kg X 24 hr


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 85 liver-5

description: 25 mg/kg X 48 hr

source_name: 25mg/kg Diquat Dibromide 48hr rat 87 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 85 liver-4

description: 25 mg/kg X 48 hr

source_name: 25mg/kg Diquat Dibromide 48hr rat 86 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-5

description: 25 mg/kg X 24 hr

source_name: 25mg/kg Diquat Dibromide 24hr rat 59 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-4

description: 25 mg/kg X 24 hr

source_name: 25mg/kg Diquat Dibromide 24hr rat 57 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 85 liver-3

description: 25 mg/kg X 48 hr

source_name: 25mg/kg Diquat Dibromide 48hr rat 85 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 85 liver-2

description: 25 mg/kg X 48 hr

source_name: 0mg/kg Diquat Dibromide 48hr rat liver pool


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-10

description: 20 mg/kg X 6 hr


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 85 liver-6

description: 25 mg/kg X 48 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-3

description: 25 mg/kg X 24 hr

source_name: 25mg/kg Diquat Dibromide 24hr rat 58 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-7

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 44 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-7

description: 5 mg/kg X 24 hr

source_name: 5mg/kg Diquat Dibromide 24hr rat 42 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-6

description: 10 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-6

description: 5 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-8

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 45 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-5

description: 5 mg/kg X 24 hr

source_name: 5mg/kg Diquat Dibromide 24hr rat 41 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-5

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 43 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-2

description: 5 mg/kg X 24 hr

source_name: 5mg/kg Diquat Dibromide 24hr rat 40 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-11

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 46 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-12

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 47 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-3

description: 5 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-10

description: 10 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-9

description: 10 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-4

description: 5 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-8

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 52 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-4

description: 10 mg/kg X 24 hr

source_name: 0mg/kg Diquat Dibromide 24hr rat liver pool


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-7

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 51 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-6

description: 20 mg/kg X 24 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-5

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 50 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-8

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 7 liver

source_name: 0mg/kg Diquat Dibromide 6hr rat liver pool


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-9

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 8 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-7

description: 5 mg/kg X 6 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-4

description: 20 mg/kg X 24 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-8

description: 20 mg/kg X 6 hr

source_name: 20mg/kg Diquat Dibromide 6hr rat 22 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-6

description: 20 mg/kg X 6 hr

source_name: 20mg/kg Diquat Dibromide 6hr rat 21 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-4

description: 20 mg/kg X 6 hr

source_name: 20mg/kg Diquat Dibromide 6hr rat 20 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-1

description: 20 mg/kg X 6 hr

source_name: 20mg/kg Diquat Dibromide 6hr rat 19 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-7

description: 10 mg/kg X 6 hr

source_name: 10mg/kg Diquat Dibromide 6hr rat 18 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 76 liver-1

description: 10 mg/kg X 48 hr

source_name: 10mg/kg Diquat Dibromide 48hr rat 73 liver

source_name: 0mg/kg Diquat Dibromide 48hr rat liver pool


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-7

description: 20 mg/kg X 6 hr


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 83 liver-1

description: 20 mg/kg X 48 hr

source_name: 20mg/kg Diquat Dibromide 48hr rat 84 liver


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 85 liver-1

description: 25 mg/kg X 48 hr

source_name: 25mg/kg Diquat Dibromide 48hr rat 86 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-2

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 49 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-5

description: 20 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-2

description: 20 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 19 liver-3

description: 20 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-6

description: 10 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-5

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 9 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-3

description: 20 mg/kg X 24 hr

source_name: 0mg/kg Diquat Dibromide 24hr rat liver pool


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-6

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 10 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-2

description: 25 mg/kg X 24 hr

source_name: 25mg/kg Diquat Dibromide 24hr rat 57 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 59 liver-1

description: 25 mg/kg X 24 hr

source_name: 25mg/kg Diquat Dibromide 24hr rat 59 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-3

description: 10 mg/kg X 6 hr

source_name: 10mg/kg Diquat Dibromide 6hr rat 16 liver

source_name: 0mg/kg Diquat Dibromide 6hr rat liver pool


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-5

description: 10 mg/kg X 6 hr

source_name: 10mg/kg Diquat Dibromide 6hr rat 17 liver


title: arg2- rep2

type: genomic

city: Boston

first: Amnon

last: Koren

state: MA

address: 77 Avenue Louis Pasteur

department: Genetics

institute: Harvard Medical School

description:
raw data column: Strains18 (block2)
S vs G1 Replication timing

hyb_protocol: Agilent

scan_protocol: Agilent, 5micron, 100%PMT

data_processing: Images were analyzed with SpotReader (Niles Scientific). Weak (<2std above control probe mean) and saturated probe reads were removed from further analysis. Data was LOWESS-normalized.

molecule: genomic DNA

organism: Saccharomyces cerevisiae

source_name: G1-phase cells

label_protocol: DNA was digested with DpnII and amplified by four ronds of random-octamer-primed Exo-Klenow DNA synthesis (Invitrogen BioPrime ArrayCGH amplification kit) with amino-allyl modified nucleotides and subsequently labeled with Cy dyes

growth_protocol: Cells were grown in YPD (1% yeast extract, 2% peptone, 2% dextrose) at 30º to log phase and fixated.

extract_protocol: DNA was extracted using the MasterPure Yeast DNA purification kit (Epicentre)

treatment_protocol: G1- and S- phase cells were sorted by FACS

source_name: S-phase cells


title: Diquat Dibromide 48hr rat liver pool vs. Diquat Dibromide 48hr rat 67 liver-1

description: 5 mg/kg X 48 hr

source_name: 5mg/kg Diquat Dibromide 48hr rat 67 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 54 liver-1

description: 20 mg/kg X 24 hr

source_name: 20mg/kg Diquat Dibromide 24hr rat 54 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-4

description: 5 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-3

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 8 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-2

description: 10 mg/kg X 6 hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-4

description: 10 mg/kg X 6 hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 046 liver-1

description: 250 mg/kg/day X 48 Hr

source_name: 250mg/kg/day bromobenzene 48Hr rat 046 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 40 liver-1

description: 5 mg/kg X 24 hr

source_name: 5mg/kg Diquat Dibromide 24hr rat 39 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-2

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 48 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 16 liver-1

description: 10 mg/kg X 6 hr

source_name: 10mg/kg Diquat Dibromide 6hr rat 15 liver


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-1

description: 5 mg/kg X 6 hr

source_name: 5mg/kg Diquat Dibromide 6hr rat 12 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 046 liver-2

description: 250 mg/kg/day X 48 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 047 liver-1

description: 250 mg/kg/day X 48 Hr

source_name: 250mg/kg/day bromobenzene 48Hr rat 047 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 047 liver-2

description: 250 mg/kg/day X 48 Hr


title: Diquat Dibromide 6hr rat liver pool vs. Diquat Dibromide 6hr rat 12 liver-2

description: 5 mg/kg X 6 hr


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-3

description: 10 mg/kg X 24 hr

source_name: 0mg/kg Diquat Dibromide 24hr rat liver pool


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 045 liver-2

description: 250 mg/kg/day X 48 Hr

source_name: 250mg/kg/day bromobenzene 48Hr rat 045 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 029 liver-2

description: 250 mg/kg/day X 24 Hr

source_name: 250mg/kg/day bromobenzene 24Hr rat 029 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 030 liver-2

description: 250 mg/kg/day X 24 Hr

source_name: 250mg/kg/day bromobenzene 24Hr rat 030 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 028 liver-1

description: 75 mg/kg/day X 24 Hr

source_name: 75mg/kg/day bromobenzene 24Hr rat 028 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 027 liver-2

description: 75 mg/kg/day X 24 Hr

source_name: 75mg/kg/day bromobenzene 24Hr rat 027 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 026 liver-1

description: 75 mg/kg/day X 24 Hr

source_name: 75mg/kg/day bromobenzene 24Hr rat 026 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 045 liver-1

description: 250 mg/kg/day X 48 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 029 liver-1

description: 250 mg/kg/day X 24 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 043 liver-2

description: 75 mg/kg/day X 48 Hr

source_name: 75mg/kg/day bromobenzene 48Hr rat 043 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 044 liver-1

description: 75 mg/kg/day X 48 Hr

source_name: 75mg/kg/day bromobenzene 48Hr rat 044 liver


title: Diquat Dibromide 24hr rat liver pool vs. Diquat Dibromide 24hr rat 48 liver-1

description: 10 mg/kg X 24 hr

source_name: 10mg/kg Diquat Dibromide 24hr rat 47 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 026 liver-2

description: 75 mg/kg/day X 24 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 028 liver-2

description: 75 mg/kg/day X 24 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 042 liver-1

description: 75 mg/kg/day X 48 Hr

source_name: 75mg/kg/day bromobenzene 48Hr rat 042 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 044 liver-2

description: 75 mg/kg/day X 48 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 042 liver-2

description: 75 mg/kg/day X 48 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 037 liver-2

description: 25 mg/kg/day X 48 Hr

source_name: 25mg/kg/day bromobenzene 48Hr rat 037 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 048 liver-2

description: 250 mg/kg/day X 48 Hr

source_name: 250mg/kg/day bromobenzene 48Hr rat 048 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 040 liver-2

description: 25 mg/kg/day X 48 Hr

source_name: 25mg/kg/day bromobenzene 48Hr rat 040 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 037 liver-1

description: 25 mg/kg/day X 48 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 041 liver-2

description: 75 mg/kg/day X 48 Hr

source_name: 75mg/kg/day bromobenzene 48Hr rat 041 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 032 liver-1

description: 250 mg/kg/day X 24 Hr

source_name: 250mg/kg/day bromobenzene 24Hr rat 032 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 041 liver-1

description: 75 mg/kg/day X 48 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 031 liver-1

description: 250 mg/kg/day X 24 Hr

source_name: 250mg/kg/day bromobenzene 24Hr rat 031 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 048 liver-1

description: 250 mg/kg/day X 48 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 025 liver-2

description: 75 mg/kg/day X 24 Hr

source_name: 75mg/kg/day bromobenzene 24Hr rat 025 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 024 liver-2

description: 25 mg/kg/day X 24 Hr

source_name: 25mg/kg/day bromobenzene 24Hr rat 024 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 024 liver-1

description: 25 mg/kg/day X 24 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 032 liver-2

description: 250 mg/kg/day X 24 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 038 liver-2

description: 25 mg/kg/day X 48 Hr

source_name: 25mg/kg/day bromobenzene 48Hr rat 038 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 038 liver-1

description: 25 mg/kg/day X 48 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 040 liver-1

description: 25 mg/kg/day X 48 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 009 liver-2

description: 75 mg/kg/day X 6 Hr

source_name: 75mg/kg/day bromobenzene 6Hr rat 009 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 008 liver-2

description: 25 mg/kg/day X 6 Hr

source_name: 25mg/kg/day bromobenzene 6Hr rat 008 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 007 liver-2

description: 25 mg/kg/day X 6 Hr

source_name: 25mg/kg/day bromobenzene 6Hr rat 007 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 008 liver-1

description: 25 mg/kg/day X 6 Hr


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 039 liver-2

description: 25 mg/kg/day X 48 Hr

source_name: 25mg/kg/day bromobenzene 48Hr rat 039 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 007 liver-1

description: 25 mg/kg/day X 6 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 025 liver-1

description: 75 mg/kg/day X 24 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 006 liver-1

description: 25 mg/kg/day X 6 Hr

source_name: 25mg/kg/day bromobenzene 6Hr rat 006 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 009 liver-1

description: 75 mg/kg/day X 6 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 011 liver-2

description: 75 mg/kg/day X 6 Hr

source_name: 75mg/kg/day bromobenzene 6Hr rat 011 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 011 liver-1

description: 75 mg/kg/day X 6 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 010 liver-1

description: 75 mg/kg/day X 6 Hr

source_name: 75mg/kg/day bromobenzene 6Hr rat 010 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 005 liver-2

description: 25 mg/kg/day X 6 Hr

source_name: 25mg/kg/day bromobenzene 6Hr rat 005 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 012 liver-2

description: 75 mg/kg/day X 6 Hr

source_name: 75mg/kg/day bromobenzene 6Hr rat 012 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 010 liver-2

description: 75 mg/kg/day X 6 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 023 liver-2

description: 25 mg/kg/day X 24 Hr

source_name: 25mg/kg/day bromobenzene 24Hr rat 023 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 006 liver-2

description: 25 mg/kg/day X 6 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 023 liver-1

description: 25 mg/kg/day X 24 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 005 liver-1

description: 25 mg/kg/day X 6 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 021 liver-2

description: 25 mg/kg/day X 24 Hr

source_name: 25mg/kg/day bromobenzene 24Hr rat 021 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 022 liver-2

description: 25 mg/kg/day X 24 Hr

source_name: 25mg/kg/day bromobenzene 24Hr rat 022 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 021 liver-1

description: 25 mg/kg/day X 24 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 016 liver-1

description: 250 mg/kg/day X 6 Hr

source_name: 250mg/kg/day bromobenzene 6Hr rat 016 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 015 liver-2

description: 250 mg/kg/day X 6 Hr

source_name: 250mg/kg/day bromobenzene 6Hr rat 015 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 016 liver-2

description: 250 mg/kg/day X 6 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 015 liver-1

description: 250 mg/kg/day X 6 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 014 liver-2

description: 250 mg/kg/day X 6 Hr

source_name: 250mg/kg/day bromobenzene 6Hr rat 014 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 014 liver-1

description: 250 mg/kg/day X 6 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 013 liver-2

description: 250 mg/kg/day X 6 Hr

source_name: 250mg/kg/day bromobenzene 6Hr rat 013 liver


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 013 liver-1

description: 250 mg/kg/day X 6 Hr


title: 4609 Pool 1-4 vs. bromobenzene 6Hr rat 012 liver-1

description: 75 mg/kg/day X 6 Hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 030 liver-1

description: 250 mg/kg/day X 24 Hr

source_name: 250mg/kg/day bromobenzene 24Hr rat 030 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 043 liver-1

description: 75 mg/kg/day X 48 Hr

source_name: 75mg/kg/day bromobenzene 48Hr rat 043 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 005 liver-1

description: 15 mg/kg X 6 hr

source_name: 0 mg/kg 1,4_Dichlorobenzene 6 hr rat liver pool

source_name: 15 mg/kg 1,4_Dichlorbenzene 6 hr rat 005 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 022 liver-1

description: 25 mg/kg/day X 24 Hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 006 liver-1

description: 15 mg/kg X 6 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 6 hr rat 006 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 007 liver-2

description: 15 mg/kg X 6 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 6 hr rat 007 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 005 liver-2

description: 15 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 008 liver-1

description: 15 mg/kg X 6 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 6 hr rat 008 liver


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 031 liver-2

description: 250 mg/kg/day X 24 Hr

source_name: 250mg/kg/day bromobenzene 24Hr rat 031 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 008 liver-2

description: 15 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 009 liver-1

description: 150 mg/kg X 6 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 6 hr rat 009 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 009 liver-2

description: 150 mg/kg X 6 hr


title: 4611 Pool 17-20 vs. bromobenzene 24Hr rat 027 liver-1

description: 75 mg/kg/day X 24 Hr

source_name: 75mg/kg/day bromobenzene 24Hr rat 027 liver


title: 4613 Pool 33-36 vs. bromobenzene 48Hr rat 039 liver-1

description: 25 mg/kg/day X 48 Hr

source_name: 25mg/kg/day bromobenzene 48Hr rat 039 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 048 liver-1

description: 1500 mg/kg X 48 hr

source_name: 0 mg/kg 1,4_Dichlorobenzene 48 hr rat liver pool

source_name: 1500 mg/kg 1,4_Dichlorbenzene 48 hr rat 048 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 047 liver-2

description: 1500 mg/kg X 48 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 48 hr rat 047 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 028 liver-2

description: 150 mg/kg X 24 hr

source_name: 0 mg/kg 1,4_Dichlorobenzene 24 hr rat liver pool

source_name: 150 mg/kg 1,4_Dichlorbenzene 24 hr rat 028 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 027 liver-2

description: 150 mg/kg X 24 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 24 hr rat 027 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 047 liver-1

description: 1500 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 048 liver-2

description: 1500 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 026 liver-2

description: 150 mg/kg X 24 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 24 hr rat 026 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 007 liver-1

description: 15 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 039 liver-2

description: 15 mg/kg X 48 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 48 hr rat 039 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 041 liver-2

description: 150 mg/kg X 48 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 48 hr rat 041 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 026 liver-1

description: 150 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 030 liver-1

description: 1500 mg/kg X 24 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 24 hr rat 030 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 040 liver-1

description: 15 mg/kg X 48 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 48 hr rat 040 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 029 liver-2

description: 1500 mg/kg X 24 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 24 hr rat 029 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 030 liver-2

description: 1500 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 029 liver-1

description: 1500 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 024 liver-2

description: 15 mg/kg X 24 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 24 hr rat 024 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 040 liver-2

description: 15 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 028 liver-1

description: 150 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 025 liver-2

description: 150 mg/kg X 24 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 24 hr rat 025 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 044 liver-2

description: 150 mg/kg X 48 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 48 hr rat 044 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 025 liver-1

description: 150 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 024 liver-1

description: 15 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 023 liver-2

description: 15 mg/kg X 24 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 24 hr rat 023 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 013 liver-1

description: 1500 mg/kg X 6 hr

source_name: 0 mg/kg 1,4_Dichlorobenzene 6 hr rat liver pool

source_name: 1500 mg/kg 1,4_Dichlorbenzene 6 hr rat 013 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 046 liver-2

description: 1500 mg/kg X 48 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 48 hr rat 046 liver

source_name: 0 mg/kg 1,4_Dichlorobenzene 48 hr rat liver pool


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 013 liver-2

description: 1500 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 046 liver-1

description: 1500 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 014 liver-2

description: 1500 mg/kg X 6 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 6 hr rat 014 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 012 liver-2

description: 150 mg/kg X 6 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 6 hr rat 012 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 044 liver-1

description: 150 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 037 liver-2

description: 15 mg/kg X 48 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 48 hr rat 037 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 006 liver-2

description: 15 mg/kg X 6 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 6 hr rat 006 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 042 liver-2

description: 150 mg/kg X 48 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 48 hr rat 042 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 037 liver-1

description: 15 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 043 liver-1

description: 150 mg/kg X 48 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 48 hr rat 043 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 038 liver-1

description: 15 mg/kg X 48 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 48 hr rat 038 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 014 liver-1

description: 1500 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 038 liver-2

description: 15 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 042 liver-1

description: 150 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 045 liver-1

description: 1500 mg/kg X 48 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 48 hr rat 045 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 039 liver-1

description: 15 mg/kg X 48 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 48 hr rat 039 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 045 liver-2

description: 1500 mg/kg X 48 hr


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 041 liver-1

description: 150 mg/kg X 48 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 48 hr rat 041 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 012 liver-1

description: 150 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 027 liver-1

description: 150 mg/kg X 24 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 24 hr rat 027 liver

source_name: 0 mg/kg 1,4_Dichlorobenzene 24 hr rat liver pool


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 031 liver-2

description: 1500 mg/kg X 24 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 24 hr rat 031 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 011 liver-1

description: 150 mg/kg X 6 hr

source_name: 0 mg/kg 1,4_Dichlorobenzene 6 hr rat liver pool

source_name: 150 mg/kg 1,4_Dichlorbenzene 6 hr rat 011 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 010 liver-2

description: 150 mg/kg X 6 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 6 hr rat 010 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 023 liver-1

description: 15 mg/kg X 24 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 24 hr rat 023 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 032 liver-2

description: 1500 mg/kg X 24 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 24 hr rat 032 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 022 liver-2

description: 15 mg/kg X 24 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 24 hr rat 022 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 031 liver-1

description: 1500 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 021 liver-1

description: 15 mg/kg X 24 hr

source_name: 15 mg/kg 1,4_Dichlorbenzene 24 hr rat 021 liver


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 011 liver-2

description: 150 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 016 liver-1

description: 1500 mg/kg X 6 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 6 hr rat 016 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 021 liver-2

description: 15 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 015 liver-1

description: 1500 mg/kg X 6 hr

source_name: 1500 mg/kg 1,4_Dichlorbenzene 6 hr rat 015 liver


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 022 liver-1

description: 15 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 010 liver-1

description: 150 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 016 liver-2

description: 1500 mg/kg X 6 hr


title: 1,4_Dichlorobenzene 24 hr rat liver pool vs. 1,4_Dichlorbenzene 24 hr rat 032 liver-1

description: 1500 mg/kg X 24 hr


title: 1,4_Dichlorobenzene 6 hr rat liver pool vs. 1,4_Dichlorbenzene 6 hr rat 015 liver-2

description: 1500 mg/kg X 6 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 038.0 liver-2

description: 15 mg/kg/day X 48 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 038.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 038.0 liver-1

description: 15 mg/kg/day X 48 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 041.0 liver-1

description: 150 mg/kg/day X 48 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 041.0 liver


title: 1,4_Dichlorobenzene 48 hr rat liver pool vs. 1,4_Dichlorbenzene 48 hr rat 043 liver-2

description: 150 mg/kg X 48 hr

source_name: 150 mg/kg 1,4_Dichlorbenzene 48 hr rat 043 liver

source_name: 0 mg/kg 1,4_Dichlorobenzene 48 hr rat liver pool


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 040.0 liver-1

description: 15 mg/kg/day X 48 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 040.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 040.0 liver-2

description: 15 mg/kg/day X 48 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 037.0 liver-2

description: 15 mg/kg/day X 48 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 037.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 023.0 liver-2

description: 15 mg/kg/day X 24 hr

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 023.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 024.0 liver-1

description: 15 mg/kg/day X 24 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 024.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 039.0 liver-2

description: 15 mg/kg/day X 48 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 039.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 021.0 liver-1

description: 15 mg/kg/day X 24 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 021.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 021.0 liver-2

description: 15 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 028.0 liver-2

description: 150 mg/kg/day X 24 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 028.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 032.0 liver-2

description: 1500 mg/kg/day X 24 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 032.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 029.0 liver-2

description: 1500 mg/kg/day X 24 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 029.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 029.0 liver-1

description: 1500 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 028.0 liver-1

description: 150 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 007.0 liver-2

description: 15 mg/kg/day X 6 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 007.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 009.0 liver-2

description: 150 mg/kg/day X 6 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 009.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 027.0 liver-2

description: 150 mg/kg/day X 24 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 027.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 009.0 liver-1

description: 150 mg/kg/day X 6 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 043.0 liver-2

description: 150 mg/kg/day X 48 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 043.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 013.0 liver-2

description: 1500 mg/kg/day X 6 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 013.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 012.0 liver-2

description: 150 mg/kg/day X 6 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 012.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 044.0 liver-2

description: 150 mg/kg/day X 48 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 044.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 043.0 liver-1

description: 150 mg/kg/day X 48 hr


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 011.0 liver-2

description: 150 mg/kg/day X 6 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 011.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 010.0 liver-2

description: 150 mg/kg/day X 6 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 010.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 008.0 liver-2

description: 15 mg/kg/day X 6 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 008.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 008.0 liver-1

description: 15 mg/kg/day X 6 hr


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 025.0 liver-2

description: 150 mg/kg/day X 24 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 025.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 025.0 liver-1

description: 150 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 039.0 liver-1

description: 15 mg/kg/day X 48 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 039.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 022.0 liver-2

description: 15 mg/kg/day X 24 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 022.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 026.0 liver-1

description: 150 mg/kg/day X 24 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 026.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 037.0 liver-1

description: 15 mg/kg/day X 48 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 037.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene  48hr Rat 048.0 liver-1

description: 1500 mg/kg/day X 48 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 048.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 013.0 liver-1

description: 1500 mg/kg/day X 6 hr

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 024.0 liver-2

description: 15 mg/kg/day X 24 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 024.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 015.0 liver-2

description: 1500 mg/kg/day X 6 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 015.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 012.0 liver-1

description: 150 mg/kg/day X 6 hr


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 022.0 liver-1

description: 15 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 042.0 liver-2

description: 150 mg/kg/day X 48 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 042.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene  48hr Rat 047.0 liver-1

description: 1500 mg/kg/day X 48 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 047.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 026.0 liver-2

description: 150 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 014.0 liver-2

description: 1500 mg/kg/day X 6 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 014.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene  48hr Rat 048.0 liver-2

description: 1500 mg/kg/day X 48 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 044.0 liver-1

description: 150 mg/kg/day X 48 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 044.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 016.0 liver-1

description: 1500 mg/kg/day X 6 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 016.0 liver


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene  48hr Rat 047.0 liver-2

description: 1500 mg/kg/day X 48 hr


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 041.0 liver-2

description: 150 mg/kg/day X 48 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 041.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 016.0 liver-2

description: 1500 mg/kg/day X 6 hr


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 015.0 liver-1

description: 1500 mg/kg/day X 6 hr


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 032.0 liver-1

description: 1500 mg/kg/day X 24 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 032.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 010.0 liver-1

description: 150 mg/kg/day X 6 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 010.0 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 031.0 liver-2

description: 1500 mg/kg/day X 24 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 031.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 005.0 liver-1

description: 15 mg/kg/day X 6 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 005.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 006.0 liver-2

description: 15 mg/kg/day X 6 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 006.0 liver


title: Primary hepatocyte cadmium, biological rep 2

status: Public on Feb 25 2009

city: Kalamazoo

first: Susan

middle: R

last: Stapleton

state: MI

address: 3425 Wood Hall

department: Chemistry

institute: Western Michigan University

description: gene expression data from primary rat hepatocyte in culture

hyb_protocol: Following fragmentation, 15 μg of cRNA were hybridized for 16 hrs at 45°C on RAE 230A Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.

scan_protocol: GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G2500A.

data_processing: The data were analyzed with Microarray Suite version 5.0 (MAS 5.0) using Affymetrix default analysis settings and global scaling as normalization method.

label: biotin

source_name: primary hepatocyte in culture from rat 2

label_protocol: Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 8 μg total RNA (Expression Analysis Technical Manual, 701022 Rev. 2, Affymetrix).

growth_protocol: Primary rat heaptocytes were isolated, plated in culture dishes and incubated overnight prior to treatment of either control group (culture media) or cadmium group.

extract_protocol: Trizol extraction of total RNA was performed according to the manufacturer's instructions.

treatment_protocol: Primary rat hepatocytes in culture are incubated with low concentration of cadmium chloride (4μM) for 3 hours or nothing (culture media only).

tag: agent

value: cadmium

tag: dose

tag: time


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 011.0 liver-1

description: 150 mg/kg/day X 6 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 011.0 liver

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 027.0 liver-1

description: 150 mg/kg/day X 24 hr

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 027.0 liver


title: Primary hepatocyte control, biological rep 2

value: control


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 006.0 liver-1

description: 15 mg/kg/day X 6 hr


title: Primary hepatocyte cadmium, biological rep 4

source_name: primary hepatocyte in culture from rat 4


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 030.0 liver-1

description: 1500 mg/kg/day X 24 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 030.0 liver


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 007.0 liver-1

description: 15 mg/kg/day X 6 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 007.0 liver


title: Primary hepatocyte control, biological rep 3

source_name: primary hepatocyte in culture from rat 3


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 005.0 liver-2

description: 15 mg/kg/day X 6 hr


title: Primary hepatocyte control, biological rep 4


title: Primary hepatocyte control, biological rep 1

source_name: primary hepatocyte in culture from rat 1


title: Primary hepatocyte cadmium, biological rep 3


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 023.0 liver-1

description: 15 mg/kg/day X 24 hr

source_name: 15 mg/kg/day 1,2-Dichlorobenzene 24hr Rat 023.0 liver


title: Hepatitis/cirrhotic liver (P.NY682)

status: Public on Oct 15 2008

city: Dallas

first: Yujin

last: Hoshida

state: TX

address: 5323 Harry Hines Blvd

institute: University of Texas Southwestern Medical Center

hyb_protocol: Refer to the Illumina DASL Assay System Manual. Hybridization was performed for 4 DASL assay oligo pool (DAP)s, DAP1~4, including 1536 probes each on 4 separate microarrays.

data_processing: For each probe, Red and Green intensities are computed as average of single bead values. The final signal is the sum of the Red and Green intensities. Data were were then normalized using the cubic spline algorithm for each DAP.

label: Cy3 and Cy5

organism: Homo sapiens

source_name: hepatitis/cirrhotic liver

extract_protocol: Using 10µm sections taken from formalin-fixed paraffin-embeded tissue blocks, total RNA was extracted using TRIzol LS reagent (Invitrogen) with semi-automated robotic extraction.

tag: used for prognostic prediction

value: No

tag: clinical data

value: withheld from GEO due to privacy concerns


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 031.0 liver-1

description: 1500 mg/kg/day X 24 hr


title: 1,2-Dichlorobenzene 24hr Rat Pool 4617 liver vs. 1,2-Dichlorobenzene 24hr Rat 030.0 liver-2

description: 1500 mg/kg/day X 24 hr


title: Hepatitis/cirrhotic liver (P.NY85)

scan_protocol: Refer to the Illumina DASL Assay System Manual

tag: corresponding tumor sample in gse19977

value: Yes


title: 1,2-Dichlorobenzene 6hr Rat Pool 4615 liver vs. 1,2-Dichlorobenzene 6hr Rat 014.0 liver-1

description: 1500 mg/kg/day X 6 hr

source_name: 1500 mg/kg/day 1,2-Dichlorobenzene 6hr Rat 014.0 liver


title: Hepatitis/cirrhotic liver (P.NY680)

label_protocol: Refer to the Illumina DASL Assay System Manual


title: Hepatitis/cirrhotic liver (P.NY678)


title: Primary hepatocyte cadmium, biological rep 1


title: Hepatitis/cirrhotic liver (P.NY670)


title: Hepatitis/cirrhotic liver (P.NY664)


title: Hepatitis/cirrhotic liver (P.NY674)


title: Hepatitis/cirrhotic liver (P.NY676)


title: Hepatitis/cirrhotic liver (P.NY658)


title: Hepatitis/cirrhotic liver (P.NY662)


title: Hepatitis/cirrhotic liver (P.NY660)


title: Hepatitis/cirrhotic liver (P.NY668)


title: Hepatitis/cirrhotic liver (P.NY656)


title: Hepatitis/cirrhotic liver (P.NY67)


title: Hepatitis/cirrhotic liver (P.NY666)


title: Hepatitis/cirrhotic liver (P.NY648)


title: Hepatitis/cirrhotic liver (P.NY650)


title: 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver vs. 1,2-Dichlorobenzene 48hr Rat 042.0 liver-1

description: 150 mg/kg/day X 48 hr

source_name: 0 mg/kg/day 1,2-Dichlorobenzene 48hr Rat Controls 4619 liver

source_name: 150 mg/kg/day 1,2-Dichlorobenzene 48hr Rat 042.0 liver


title: NSCB_CGH_390K_227669

status: Public on Dec 12 2008

city: Madison

first: Melodee

last: Patterson

state: WI

address: 510 Charmany Dr Ste 58 & 59

institute: WiCell

description: This CGH experiment is designed to detect deletion, insertation, amplication, etc. in the sample relative to the reference.

hyb_protocol: 1. Incubate at 95°C (in heat block), 5 min., spin briefly 2. Place at 42°C (in Maui machine), 5-15 min. 3. Prepare microarray: A) pre-heat array on Maui station B) put array into array-holder (with number facing up going in first) carefully remove glue-sticker from lid and put lid onto array C) take array w/ lid out of array-holder thoroughly attach lid using thick slide place array onto Maui station, approx. 2 min. make sure lid is completely attached D) Add 40 µl hyb solution onto microarray and allow to settle (approx. 15 sec.), dry lid thoroughly 4. Place stickers onto lid, press down on both at the same time, make sure are thoroughly attached 5. Squeeze bubbles away from center of array 6. Wet humid cover and place on Maui station 7. Incubate on Maui at 42°C overnight (17 hours) 8. Remove microarray w/lid from Maui and put in array-holder in Wash 1 (at 42°C) 9. Peel lid off chip while submerged 10. Incubate 10-15 sec. w/ gentle agitation 11. Transfer slide into a slide rack in a new container of Wash 1 (r.t.) Incubate 2 min. w/ gentle agitation 12. Transfer to Wash 2 13. Incubate 1 min. w/ gentle agitation 14. Transfer to Wash 3 15. Incubate 15 sec. w/ gentle agitation 16. Spin approx. 1 min. in Array-Go-Round (place arrays such that numbers are facing to the right when rack is placed in front part of wheel) (the rod on slide holder should be on the inside) 17. Blow off any residual liquid 18. Keep slides protected from light and scan as soon as possible

scan_protocol: NimbleGen scan protocol

data_processing:
1. Image extraction: NimbleScan provided by NimbleGen is used to extract signal data from image files (*.TFF). Signals from the scan for Cy3 (green channel) are saved in a file named as chipID_532.pair while signals from the scan for Cy5 (red channel) are saved in a file named as chipID_635.pair.
2. Normalization: Signals from Cy3/Cy5 channels are transformed by logarithms to base 2 and normalized with loess or qspline (Workman et al., 2002) algorithms by R to resolve the systematic errors and bias introduced by the microarray experimental platform. The log ratios of the signals are obtained by subtracting the log transformed signals from one channel by the corresponding ones from another channel.
3. Data smoothing and break-points identification: Ratios of the normalized data are plotted by the corresponding genome locations. The data are smoothed by an adaptive weights smoothing algorithm (GLAD R-package, Wang et al., 2005), break-points are identified by a binary segmentation algorithm (DNAcopy R-package, Olshen et al., 2004) or by the segmentation algorithm available within Nimbelgen’s Nimblescan software.
4. Data visualization: CGH results can be saved as SignalMap GFF files and can be visualized by SignalMap provided by NimbleGen. CGH results can also be visualized by other software, such as aCGHViewer (Shankar et al., 2006), CHARMView (Myers et al., 2005), etc. However, different software requires different input format.

label_protocol:
1. Dry the sample in the Speed Vac set at 30°C.
2. Resuspend the sample in 4.5μl 0.1 M Na2CO3, pH 9.0.
3. Resuspend the Cy3 NHS ester in 4.5μl DMSO
4. Add Cy3 NHS ester to sample
5. Incubate at 22°C in a heat block for 1 hour. Protect the heat block and sample from light.
6. Purify the sample using a Qiaquick PCR purification Kit:
A) Add 35μl 100 mM NaOAc, pH 5.2 to the sample.
B) Add 250μl PB buffer to the sample and load the sample on the column.
C) Spin at 13.000 rpm for 1 minute and remove the flow through.
D) Add 750μl PE buffer to the column.
E) Spin at 13.000 rpm for 1 minute and remove the flow through.
F) Spin at 13.000 rpm for 1 minute.
G) Transfer the column to new tube.
H) Add 30μl H20 and incubate for 1 minute on the column.
I) Elute once by centrifuging at 13.000 rpm for 1 minute.

extract_protocol:
1. Determine When to Harvest hES cells for DNA Extraction
A) At least 1x10^6 hES cells should be harvested for DNA extraction, depending on the quantity required.
B) Yields of genomic DNA will vary from sample to sample depending on the amount and type of cells processed. In addition, the quality of starting material will affect DNA yield.
C) Estimated yield for hES cells: 5pg of DNA per cell (5μg DNA per 10^6 cells). One well of a 6-well plate will normally have between 1-4x106 hES cells by day 5 after passage.
2. Trypsinize the Cells
A) The following steps should be performed in a sterile biosafety cabinet while wearing personal protective equipment.
B) Add 1.5ml of 1X trypsin-EDTA working solution (pre-warmed to 37oC) to each well of a 6- well plate.
C) Return the plate to the 37C incubator for 2-3 minutes.
D) Remove the plate from the incubator and observe cell detachment with an inverted phase contrast microscope. Proceed to next step when colony edges begin to lift off the plate.
E) Using a sterile glass serological pipet, gently pipet up and down to detach the cells and break up the cell clumps.
F) Pool the detached cells in a 15ml centrifuge tube containing 5ml of trypsin stop solution within 5-7 minutes of adding the trypsin-EDTA solution.
G) Gently pipet the solution up and down to mix thoroughly.
H) Centrifuge the tube for 5 minutes at 1000 RPM.
3. RNA Digestion
A) Aspirate the supernatant and gently flick the tube until the pellet is resuspended.
B) Slowly add 200μl PBS to the cells while tapping gently on the tube to ensure good mixing.
C) Add 4μl RNase A (100mg/ml) and incubate at room temperature (RT) for 2 minutes.
4. Protein Digestion
A) Add 20μl Proteinase K and 200μl Buffer AL to the sample, mixing thoroughly by vortexing. It is important that the solution is immediately and thoroughly mixed by vortexing and pipetting to yield a homogenous solution.
NOTE: Do not add proteinase K directly to buffer AL.
B) Incubate the cell solution in a 70°C waterbath for 10 minutes.
5. DNA Precipitation and Separation of Cellular Components
A) Add 200μl ethanol (96-100%) to the sample, and mix thoroughly by vortexing.
B) A white precipitate may form on addition of ethanol. This precipitate does not interfere with the DNeasy procedure.
C) Pipet the mixture (including all of the precipitate) into the DNeasy Mini spin column placed in a 2ml collection tube. Centrifuge at ≥6000 x g (8000 rpm) for 1 minute. Discard flowthrough and collection tube.
NOTE: In order to obtain optimum DNA yield and quality, it is important not to overload the spin column. The maximum number of hES cells that should be used in a DNA extraction is 5x106 (normally, 2 wells of a 6-well plate). For larger amounts of starting material use multiple spin columns.
6. Wash the DNA
A) Place the DNeasy spin column in a new collection tube and add 500μl of Buffer AW1.
B) Centrifuge at ≥6000 x g (8000rpm) for 1 minute. Discard flow-through and collection tube.
C) Place the DNeasy spin column in a new collection tube and add 500μl of buffer AW2.
D) Centrifuge at 20,000 x g (14,000 rpm) for 3 minutes to dry the DNeasy membrane. Discard flow-through and collection tube.
NOTE: It is important to dry the membrane of the DNeasy Mini spin column, since residual ethanol may interfere with subsequent reactions. This centrifugation step ensures that no residual ethanol will be carried over during the following elution.
E) Following the centrifugation step, remove the DNeasy Mini spin column carefully so the column does not come into contact with the flow-through, since this will result in carryover of ethanol. If carryover of ethanol occurs, place the spin column in a new collection tube and centrifuge again for 1 minute at 20,000 x g (14,000 rpm). Again discard the flow-through and collection tube.
7. Elution
A) Place the DNeasy Mini spin column in a clean 1.5ml or 2ml microcentrifuge tube and pipet 50-200μl Buffer AE directly onto the DNeasy membrane. Incubate the column at room temperature for 1 minute and then centrifuge for 1 minute at ≥6000 x g (8000rpm) to elute.
NOTE: Elution with less than 200μl of Buffer AE increases the final DNA concentration in the elute, but also decreases the overall DNA yield.
B) Repeat elution step as described in 7 A).
NOTE: A new microcentrifuge tube can be used for the second elution step to prevent dilution of the first elute. Alternatively, to combine the two elutes, the microcentrifuge tube from step 4.7.1 can be reused for the second elution step.
NOTE: More than 200μl should not be eluted into a 1.5 ml microcentrifuge tube because the DNeasy spin column will come into contact with the elute.

tag: cell line

value: human embryonic stem (hES) cell line NSCB# 6185, CGH# 000143

extract_protocol:
1. Determine When to Harvest hES cells for DNA Extraction
A) At least 1x10^6 hES cells should be harvested for DNA extraction, depending on the quantity required.
B) Yields of genomic DNA will vary from sample to sample depending on the amount and type of cells processed. In addition, the quality of starting material will affect DNA yield.
C) Estimated yield for hES cells: 5pg of DNA per cell (5μg DNA per 10^6 cells). One well of a 6-well plate will normally have between 1-4x106 hES cells by day 5 after passage.
2. Trypsinize the Cells
A) The following steps should be performed in a sterile biosafety cabinet while wearing personal protective equipment.
B) Add 1.5ml of 1X trypsin-EDTA working solution (pre-warmed to 37oC) to each well of a 6- well plate.
C) Return the plate to the 37C incubator for 2-3 minutes.
D) Remove the plate from the incubator and observe cell detachment with an inverted phase contrast microscope. Proceed to next step when colony edges begin to lift off the plate.
E) Using a sterile glass serological pipet, gently pipet up and down to detach the cells and break up the cell clumps.
F) Pool the detached cells in a 15ml centrifuge tube containing 5ml of trypsin stop solution within 5-7 minutes of adding the trypsin-EDTA solution.
G) Gently pipet the solution up and down to mix thoroughly.
H) Centrifuge the tube for 5 minutes at 1000 RPM.
3. RNA Digestion
A) Aspirate the supernatant and gently flick the tube until the pellet is resuspended.
B) Slowly add 200μl PBS to the cells while tapping gently on the tube to ensure good mixing.
C) Add 4μl RNase A (100mg/ml) and incubate at room temperature (RT) for 2 minutes.
4. Protein Digestion
A) Add 20μl Proteinase K and 200μl Buffer AL to the sample, mixing thoroughly by vortexing. It is important that the solution is immediately and thoroughly mixed by vortexing and pipetting to yield a homogenous solution.
NOTE: Do not add proteinase K directly to buffer AL.
B) Incubate the cell solution in a 70°C waterbath for 10 minutes.
5. DNA Precipitation and Separation of Cellular Components
A) Add 200μl ethanol (96-100%) to the sample, and mix thoroughly by vortexing.
B) A white precipitate may form on addition of ethanol. This precipitate does not interfere with the DNeasy procedure.
C) Pipet the mixture (including all of the precipitate) into the DNeasy Mini spin column placed in a 2ml collection tube. Centrifuge at ≥6000 x g (8000 rpm) for 1 minute. Discard flowthrough and collection tube.
NOTE: In order to obtain optimum DNA yield and quality, it is important not to overload the spin column. The maximum number of hES cells that should be used in a DNA extraction is 5x106 (normally, 2 wells of a 6-well plate). For larger amounts of starting material use multiple spin columns.
6. Wash the DNA
A) Place the DNeasy spin column in a new collection tube and add 500μl of Buffer AW1.
B) Centrifuge at ≥6000 x g (8000rpm) for 1 minute. Discard flow-through and collection tube.
C)Place the DNeasy spin column in a new collection tube and add 500μl of buffer AW2.
D) Centrifuge at 20,000 x g (14,000 rpm) for 3 minutes to dry the DNeasy membrane. Discard flow-through and collection tube.
NOTE: It is important to dry the membrane of the DNeasy Mini spin column, since residual ethanol may interfere with subsequent reactions. This centrifugation step ensures that no residual ethanol will be carried over during the following elution.
E) Following the centrifugation step, remove the DNeasy Mini spin column carefully so the column does not come into contact with the flow-through, since this will result in carryover of ethanol. If carryover of ethanol occurs, place the spin column in a new collection tube and centrifuge again for 1 minute at 20,000 x g (14,000 rpm). Again discard the flow-through and collection tube.
7. Elution
A) Place the DNeasy Mini spin column in a clean 1.5ml or 2ml microcentrifuge tube and pipet 50-200μl Buffer AE directly onto the DNeasy membrane. Incubate the column at room temperature for 1 minute and then centrifuge for 1 minute at ≥6000 x g (8000rpm) to elute.
NOTE: Elution with less than 200μl of Buffer AE increases the final DNA concentration in the elute, but also decreases the overall DNA yield.
B) Repeat elution step as described in 7 A).
NOTE: A new microcentrifuge tube can be used for the second elution step to prevent dilution of the first elute. Alternatively, to combine the two elutes, the microcentrifuge tube from step 4.7.1 can be reused for the second elution step.
NOTE: More than 200μl should not be eluted into a 1.5 ml microcentrifuge tube because the DNeasy spin column will come into contact with the elute

value: human embryonic stem (hES) cell line H9 [reference]


title: NSCB_CGH_390K_7336002

status: Public on Nov 14 2008

value: human embryonic stem (hES) cell line NSCB# 8989


title: NSCB_CGH_390K_7335602

hyb_protocol: 1. Incubate at 95°C (in heat block), 5 min., spin briefly 2. Place at 42°C (in Maui machine), 5-15 min. 3. Prepare microarray: A) pre-heat array on Maui station B) put array into array-holder (with number facing up going in first) carefully remove glue-sticker from lid and put lid onto array C) take array w/ lid out of array-holder thoroughly attach lid using thick slide place array onto Maui station, approx. 2 min. make sure lid is completely attached D) Add 40 µl hyb solution onto microarray and allow to settle (approx. 15 sec.), dry lid thoroughly 4. Place stickers onto lid, press down on both at the same time, make sure are thoroughly attached 5. Squeeze bubbles away from center of array 6. Wet humid cover and place on Maui station 7. Incubate on Maui at 42°C overnight (17 hours) 8. Remove microarray w/lid from Maui and put in array-holder in Wash 1 (at 42°C) 9. Peel lid off chip while submerged 10. Incubate 10-15 sec. w/ gentle agitation 11. Transfer slide into a slide rack in a new container of Wash 1 (r.t.) Incubate 2 min. w/ gentle agitation 12. Transfer to Wash 2 13. Incubate 1 min. w/ gentle agitation 14. Transfer to Wash 3 15. Incubate 15 sec. w/ gentle agitation 16. Spin approx. 1 min. in Array-Go-Round (place arrays such that numbers are facing to the right when rack is placed in front part of wheel (the rod on slide holder should be on the inside) 17. Blow off any residual liquid 18. Keep slides protected from light and scan as soon as possible

value: human embryonic stem (hES) cell line NSCB# 5246

extract_protocol:
1. Determine When to Harvest hES cells for DNA Extraction
A) At least 1x10^6 hES cells should be harvested for DNA extraction, depending on the quantity required.
B) Yields of genomic DNA will vary from sample to sample depending on the amount and type of cells processed. In addition, the quality of starting material will affect DNA yield.
C) Estimated yield for hES cells: 5pg of DNA per cell (5μg DNA per 10^6 cells). One well of a 6-well plate will normally have between 1-4x106 hES cells by day 5 after passage.
2. Trypsinize the Cells
A) The following steps should be performed in a sterile biosafety cabinet while wearing personal protective equipment.
B) Add 1.5ml of 1X trypsin-EDTA working solution (pre-warmed to 37oC) to each well of a 6- well plate.
C) Return the plate to the 37C incubator for 2-3 minutes.
D) Remove the plate from the incubator and observe cell detachment with an inverted phase contrast microscope. Proceed to next step when colony edges begin to lift off the plate.
E) Using a sterile glass serological pipet, gently pipet up and down to detach the cells and break up the cell clumps.
F) Pool the detached cells in a 15ml centrifuge tube containing 5ml of trypsin stop solution within 5-7 minutes of adding the trypsin-EDTA solution.
G) Gently pipet the solution up and down to mix thoroughly.
H) Centrifuge the tube for 5 minutes at 1000 RPM.
3. RNA Digestion
A) Aspirate the supernatant and gently flick the tube until the pellet is resuspended.
B) Slowly add 200μl PBS to the cells while tapping gently on the tube to ensure good mixing.
C) Add 4μl RNase A (100mg/ml) and incubate at room temperature (RT) for 2 minutes.
4. Protein Digestion
A) Add 20μl Proteinase K and 200μl Buffer AL to the sample, mixing thoroughly by vortexing. It is important that the solution is immediately and thoroughly mixed by vortexing and pipetting to yield a homogenous solution.
NOTE: Do not add proteinase K directly to buffer AL.
B) Incubate the cell solution in a 70°C waterbath for 10 minutes.
5. DNA Precipitation and Separation of Cellular Components
A) Add 200μl ethanol (96-100%) to the sample, and mix thoroughly by vortexing.
B) A white precipitate may form on addition of ethanol. This precipitate does not interfere with the DNeasy procedure.
C) Pipet the mixture (including all of the precipitate) into the DNeasy Mini spin column placed in a 2ml collection tube. Centrifuge at ≥6000 x g (8000 rpm) for 1 minute. Discard flowthrough and collection tube.
NOTE: In order to obtain optimum DNA yield and quality, it is important not to overload the spin column. The maximum number of hES cells that should be used in a DNA extraction is 5x106 (normally, 2 wells of a 6-well plate). For larger amounts of starting material use multiple spin columns.
6. Wash the DNA
A) Place the DNeasy spin column in a new collection tube and add 500μl of Buffer AW1.
B) Centrifuge at ≥6000 x g (8000rpm) for 1 minute. Discard flow-through and collection tube.
C) Place the DNeasy spin column in a new collection tube and add 500μl of buffer AW2.
D) Centrifuge at 20,000 x g (14,000 rpm) for 3 minutes to dry the DNeasy membrane. Discard flow-through and collection tube.
NOTE: It is important to dry the membrane of the DNeasy Mini spin column, since residual ethanol may interfere with subsequent reactions. This centrifugation step ensures that no residual ethanol will be carried over during the following elution.
E) Following the centrifugation step, remove the DNeasy Mini spin column carefully so the column does not come into contact with the flow-through, since this will result in carryover of ethanol. If carryover of ethanol occurs, place the spin column in a new collection tube and centrifuge again for 1 minute at 20,000 x g (14,000 rpm). Again discard the flow-through and collection tube.
7. Elution
A) Place the DNeasy Mini spin column in a clean 1.5ml or 2ml microcentrifuge tube and pipet 50-200μl Buffer AE directly onto the DNeasy membrane. Incubate the column at room temperature for 1 minute and then centrifuge for 1 minute at ≥6000 x g (8000rpm) to elute.
NOTE: Elution with less than 200μl of Buffer AE increases the final DNA concentration in the elute, but also decreases the overall DNA yield.
B) Repeat elution step as described in 7 A).
NOTE: A new microcentrifuge tube can be used for the second elution step to prevent dilution of the first elute. Alternatively, to combine the two elutes, the microcentrifuge tube from step 4.7.1 can be reused for the second elution step.
NOTE: More than 200μl should not be eluted into a 1.5 ml microcentrifuge tube because the DNeasy spin column will come into contact with the elute


title: Hepatitis/cirrhotic liver (P.NY654)


title: NSCB_CGH_390K_7335702

value: human embryonic stem (hES) cell line NSCB# 4785


title: NSCB_CGH_390K_7335402

data_processing:
1. Image extraction:  NimbleScan provided by NimbleGen is used to extract signal data from image files  (*.TFF). Signals from the scan for Cy3 (green channel) are saved in a file named as chipID_532.pair while signals from the scan for Cy5 (red channel) are saved in a file named as chipID_635.pair.
2. Normalization: Signals from Cy3/Cy5 channels are transformed by logarithms to base 2 and normalized with loess or qspline (Workman et al., 2002) algorithms by R to resolve the systematic errors and bias introduced by the microarray experimental platform. The log ratios of the signals are obtained by subtracting the log transformed signals from one channel by the corresponding ones from another channel.
3. Data smoothing and break-points identification:  Ratios of the normalized data are plotted by the corresponding genome locations. The data are smoothed by an adaptive weights smoothing algorithm (GLAD R-package, Wang et al., 2005), break-points are identified by a binary segmentation algorithm (DNAcopy R-package, Olshen et al., 2004) or by the segmentation algorithm available within Nimbelgen’s Nimblescan software.
4. Data visualization: CGH results can be saved as SignalMap GFF files and can be visualized by SignalMap provided by NimbleGen. CGH results can also be visualized by other software, such as aCGHViewer (Shankar et al., 2006), CHARMView (Myers et al., 2005), etc. However, different software requires different input format.

value: human embryonic stem (hES) cell line NSCB# 6117


title: NSCB_CGH_390K_7335502

extract_protocol:
1. Determine When to Harvest hES cells for DNA Extraction
A) At least 1x10^6 hES cells should be harvested for DNA extraction, depending on the quantity required.
B) Yields of genomic DNA will vary from sample to sample depending on the amount and type of cells processed. In addition, the quality of starting material will affect DNA yield.
C) Estimated yield for hES cells: 5pg of DNA per cell (5μg DNA per 10^6 cells). One well of a 6-well plate will normally have between 1-4x106 hES cells by day 5 after passage.
2. Trypsinize the Cells
A) The following steps should be performed in a sterile biosafety cabinet while wearing personal protective equipment.
B) Add 1.5ml of 1X trypsin-EDTA working solution (pre-warmed to 37oC) to each well of a 6- well plate.
C) Return the plate to the 37C incubator for 2-3 minutes.
D) Remove the plate from the incubator and observe cell detachment with an inverted phase contrast microscope. Proceed to next step when colony edges begin to lift off the plate.
E) Using a sterile glass serological pipet, gently pipet up and down to detach the cells and break up the cell clumps.
F) Pool the detached cells in a 15ml centrifuge tube containing 5ml of trypsin stop solution within 5-7 minutes of adding the trypsin-EDTA solution.
G) Gently pipet the solution up and down to mix thoroughly.
H) Centrifuge the tube for 5 minutes at 1000 RPM.
3. RNA Digestion
A) Aspirate the supernatant and gently flick the tube until the pellet is resuspended.
B) Slowly add 200μl PBS to the cells while tapping gently on the tube to ensure good mixing.
C) Add 4μl RNase A (100mg/ml) and incubate at room temperature (RT) for 2 minutes.
4. Protein Digestion
A) Add 20μl Proteinase K and 200μl Buffer AL to the sample, mixing thoroughly by vortexing. It is important that the solution is immediately and thoroughly mixed by vortexing and pipetting to yield a homogenous solution.
NOTE: Do not add proteinase K directly to buffer AL.
B) Incubate the cell solution in a 70°C waterbath for 10 minutes.
5. DNA Precipitation and Separation of Cellular Components
A) Add 200μl ethanol (96-100%) to the sample, and mix thoroughly by vortexing.
B) A white precipitate may form on addition of ethanol. This precipitate does not interfere with the DNeasy procedure.
C) Pipet the mixture (including all of the precipitate) into the DNeasy Mini spin column placed in a 2ml collection tube. Centrifuge at ≥6000 x g (8000 rpm) for 1 minute. Discard flowthrough and collection tube.
NOTE: In order to obtain optimum DNA yield and quality, it is important not to overloa the spin column. The maximum number of hES cells that should be used in a DNA extraction is 5x106 (normally, 2 wells of a 6-well plate). For larger amounts of starting material use multiple spin columns.
6. Wash the DNA
A) Place the DNeasy spin column in a new collection tube and add 500μl of Buffer AW1.
B) Centrifuge at ≥6000 x g (8000rpm) for 1 minute. Discard flow-through and collection tube.
C) Place the DNeasy spin column in a new collection tube and add 500μl of buffer AW2.
D) Centrifuge at 20,000 x g (14,000 rpm) for 3 minutes to dry the DNeasy membrane. Discard flow-through and collection tube.
NOTE: It is important to dry the membrane of the DNeasy Mini spin column, since residual ethanol may interfere with subsequent reactions. This centrifugation step ensures that no residual ethanol will be carried over during the following elution.
E) Following the centrifugation step, remove the DNeasy Mini spin column carefully so the column does not come into contact with the flow-through, since this will result in carryover of ethanol. If carryover of ethanol occurs, place the spin column in a new collection tube and centrifuge again for 1 minute at 20,000 x g (14,000 rpm). Again discard the flow-through and collection tube.
7. Elution
A) Place the DNeasy Mini spin column in a clean 1.5ml or 2ml microcentrifuge tube and pipet 50-200μl Buffer AE directly onto the DNeasy membrane. Incubate the column at room temperature for 1 minute and then centrifuge for 1 minute at ≥6000 x g (8000rpm) to elute.
NOTE: Elution with less than 200μl of Buffer AE increases the final DNA concentration in the elute, but also decreases the overall DNA yield.
B) Repeat elution step as described in 7 A).
NOTE: A new microcentrifuge tube can be used for the second elution step to prevent dilution of the first elute. Alternatively, to combine the two elutes, the microcentrifuge tube from step 4.7.1 can be reused for the second elution step.
NOTE: More than 200μl should not be eluted into a 1.5 ml microcentrifuge tube because the DNeasy spin column will come into contact with the elute.

value: human embryonic stem (hES) cell line NSCB# 1086

value: human embryonic stem (hES) cell line H1 [reference]


title: NSCB_CGH_390K_16318302

value: human embryonic stem (hES) cell line NSCB# 1590, CGH# 000144


title: Hepatitis/cirrhotic liver (P.NY640)


title: Hepatitis/cirrhotic liver (P.NY642)


title: Hepatitis/cirrhotic liver (P.NY630)


title: Hepatitis/cirrhotic liver (P.NY628)


title: Hepatitis/cirrhotic liver (P.NY632)


title: Hepatitis/cirrhotic liver (P.NY646)


title: Hepatitis/cirrhotic liver (P.NY634)


title: Hepatitis/cirrhotic liver (P.NY626)


title: Hepatitis/cirrhotic liver (P.NY624)


title: Hepatitis/cirrhotic liver (P.NY636)


title: Hepatitis/cirrhotic liver (P.NY620)


title: Hepatitis/cirrhotic liver (P.NY618)


title: Hepatitis/cirrhotic liver (P.NY638)


title: Hepatitis/cirrhotic liver (P.NY612)


title: Hepatitis/cirrhotic liver (P.NY616)


title: Hepatitis/cirrhotic liver (P.NY608)


title: Hepatitis/cirrhotic liver (P.NY604)


title: Hepatitis/cirrhotic liver (P.NY610)


title: Hepatitis/cirrhotic liver (P.NY600)


title: Hepatitis/cirrhotic liver (P.NY592)


title: Hepatitis/cirrhotic liver (P.NY606)


title: Hepatitis/cirrhotic liver (P.NY594)


title: Hepatitis/cirrhotic liver (P.NY576)


title: Hepatitis/cirrhotic liver (P.NY584)


title: Hepatitis/cirrhotic liver (P.NY578)


title: Hepatitis/cirrhotic liver (P.NY590)


title: Hepatitis/cirrhotic liver (P.NY574)


title: Hepatitis/cirrhotic liver (P.NY596)


title: Hepatitis/cirrhotic liver (P.NY588)


title: Hepatitis/cirrhotic liver (P.NY580)


title: Hepatitis/cirrhotic liver (P.NY570)


title: Hepatitis/cirrhotic liver (P.NY586)


title: Hepatitis/cirrhotic liver (P.NY572)


title: Hepatitis/cirrhotic liver (P.NY602)


title: Hepatitis/cirrhotic liver (P.NY554)


title: Hepatitis/cirrhotic liver (P.NY568)


title: Hepatitis/cirrhotic liver (P.NY566)


title: Hepatitis/cirrhotic liver (P.NY598)


title: Hepatitis/cirrhotic liver (P.NY564)


title: Hepatitis/cirrhotic liver (P.NY558)


title: Hepatitis/cirrhotic liver (P.NY562)


title: Hepatitis/cirrhotic liver (P.NY560)


title: Hepatitis/cirrhotic liver (P.NY548)


title: Hepatitis/cirrhotic liver (P.NY528)


title: Hepatitis/cirrhotic liver (P.NY538)


title: Hepatitis/cirrhotic liver (P.NY552)


title: Hepatitis/cirrhotic liver (P.NY540)


title: Hepatitis/cirrhotic liver (P.NY542)


title: Hepatitis/cirrhotic liver (P.NY530)


title: Hepatitis/cirrhotic liver (P.NY522)


title: Hepatitis/cirrhotic liver (P.NY524)


title: Hepatitis/cirrhotic liver (P.NY532)


title: Hepatitis/cirrhotic liver (P.NY536)


title: Hepatitis/cirrhotic liver (P.NY550)


title: Hepatitis/cirrhotic liver (P.NY506)


title: Hepatitis/cirrhotic liver (P.NY508)


title: Hepatitis/cirrhotic liver (P.NY518)


title: Hepatitis/cirrhotic liver (P.NY512)


title: Hepatitis/cirrhotic liver (P.NY502)


title: Hepatitis/cirrhotic liver (P.NY37)


title: Hepatitis/cirrhotic liver (P.NY207)


title: Hepatitis/cirrhotic liver (P.M93)


title: Hepatitis/cirrhotic liver (P.NY227)


title: Hepatitis/cirrhotic liver (P.M97)


title: Hepatitis/cirrhotic liver (P.NY3)


title: Hepatitis/cirrhotic liver (P.NY35)


title: Hepatitis/cirrhotic liver (P.NY231)


title: Hepatitis/cirrhotic liver (P.NY317)


title: Hepatitis/cirrhotic liver (P.NY526)


title: Hepatitis/cirrhotic liver (P.M72)


title: Hepatitis/cirrhotic liver (P.M78)


title: Hepatitis/cirrhotic liver (P.M480)


title: Hepatitis/cirrhotic liver (P.M486)


title: Hepatitis/cirrhotic liver (P.M484)


title: Hepatitis/cirrhotic liver (P.M488)


title: Hepatitis/cirrhotic liver (P.M74)


title: Hepatitis/cirrhotic liver (P.NY19)


title: Hepatitis/cirrhotic liver (P.M91)


title: Hepatitis/cirrhotic liver (P.M76)


title: Hepatitis/cirrhotic liver (P.M476)


title: Hepatitis/cirrhotic liver (P.M468)


title: Hepatitis/cirrhotic liver (P.M470)


title: Hepatitis/cirrhotic liver (P.NY644)


title: Hepatitis/cirrhotic liver (P.M452)


title: Hepatitis/cirrhotic liver (P.M462)


title: Hepatitis/cirrhotic liver (P.M466)


title: Hepatitis/cirrhotic liver (P.M450)


title: Hepatitis/cirrhotic liver (P.M426)


title: Hepatitis/cirrhotic liver (P.M458)


title: Hepatitis/cirrhotic liver (P.M442)


title: Hepatitis/cirrhotic liver (P.M412)


title: Hepatitis/cirrhotic liver (P.M432)


title: Hepatitis/cirrhotic liver (P.M416)


title: Hepatitis/cirrhotic liver (P.M422)


title: Hepatitis/cirrhotic liver (P.M434)


title: Hepatitis/cirrhotic liver (P.M428)


title: Hepatitis/cirrhotic liver (P.M436)


title: Hepatitis/cirrhotic liver (P.M440)


title: Hepatitis/cirrhotic liver (P.M444)


title: Hepatitis/cirrhotic liver (P.M410)


title: Hepatitis/cirrhotic liver (P.M408)


title: Hepatitis/cirrhotic liver (P.M456)


title: Hepatitis/cirrhotic liver (P.M406)


title: Hepatitis/cirrhotic liver (P.M402)


title: Hepatitis/cirrhotic liver (P.M398)


title: Hepatitis/cirrhotic liver (P.M404)


title: Hepatitis/cirrhotic liver (P.M396)


title: Hepatitis/cirrhotic liver (P.M388)


title: Hepatitis/cirrhotic liver (P.M386)


title: Hepatitis/cirrhotic liver (P.M390)


title: Hepatitis/cirrhotic liver (P.M424)


title: Hepatitis/cirrhotic liver (P.M340)


title: Hepatitis/cirrhotic liver (P.M374)


title: Hepatitis/cirrhotic liver (P.M322)


title: Hepatitis/cirrhotic liver (P.M346)


title: Hepatitis/cirrhotic liver (P.M376)


title: Hepatitis/cirrhotic liver (P.M332)


title: Hepatitis/cirrhotic liver (P.M392)


title: Hepatitis/cirrhotic liver (P.M368)


title: Hepatitis/cirrhotic liver (P.M394)


title: Hepatitis/cirrhotic liver (P.M384)


title: Hepatitis/cirrhotic liver (P.M310)


title: Hepatitis/cirrhotic liver (P.M382)


title: Hepatitis/cirrhotic liver (P.M316)


title: Hepatitis/cirrhotic liver (P.M312)


title: Hepatitis/cirrhotic liver (P.M320)


title: Hepatitis/cirrhotic liver (P.M378)


title: Hepatitis/cirrhotic liver (P.M296)


title: Hepatitis/cirrhotic liver (P.M298)


title: Hepatitis/cirrhotic liver (P.M286)


title: Hepatitis/cirrhotic liver (P.M288)


title: Hepatitis/cirrhotic liver (P.M290)


title: Hepatitis/cirrhotic liver (P.M294)


title: Hepatitis/cirrhotic liver (P.M270)


title: Hepatitis/cirrhotic liver (P.M268)


title: Hepatitis/cirrhotic liver (P.M276)


title: Hepatitis/cirrhotic liver (P.M262)


title: Hepatitis/cirrhotic liver (P.M232)


title: Hepatitis/cirrhotic liver (P.M260)


title: Hepatitis/cirrhotic liver (P.M246)


title: Hepatitis/cirrhotic liver (P.M228)


title: Hepatitis/cirrhotic liver (P.M238)


title: Hepatitis/cirrhotic liver (P.M272)


title: Hepatitis/cirrhotic liver (P.M236)


title: Hepatitis/cirrhotic liver (P.M284)


title: Hepatitis/cirrhotic liver (P.M230)


title: Hepatitis/cirrhotic liver (P.M292)


title: Hepatitis/cirrhotic liver (P.M252)


title: Hepatitis/cirrhotic liver (P.M218)


title: Hepatitis/cirrhotic liver (P.M220)


title: Hepatitis/cirrhotic liver (P.M256)


title: Hepatitis/cirrhotic liver (P.M226)


title: Hepatitis/cirrhotic liver (P.M212)


title: Hepatitis/cirrhotic liver (P.M214)


title: Hepatitis/cirrhotic liver (P.M258)


title: Hepatitis/cirrhotic liver (P.M208)


title: Hepatitis/cirrhotic liver (P.M210)


title: Hepatitis/cirrhotic liver (P.M204)


title: Hepatitis/cirrhotic liver (P.M202)


title: Hepatitis/cirrhotic liver (P.B218)

tag: ethnicity

value: Spanish

tag: egf level

value: Low


title: Hepatitis/cirrhotic liver (P.B214)


title: Hepatitis/cirrhotic liver (P.B212)


title: Hepatitis/cirrhotic liver (P.B220)


title: Hepatitis/cirrhotic liver (P.B216)


title: Hepatitis/cirrhotic liver (P.B254)


title: Hepatitis/cirrhotic liver (P.M101)


title: Hepatitis/cirrhotic liver (P.B222)


title: Hepatitis/cirrhotic liver (P.B206)


title: Hepatitis/cirrhotic liver (P.B208)

value: High


title: Hepatitis/cirrhotic liver (P.B204)


title: Hepatitis/cirrhotic liver (P.B210)


title: Hepatitis/cirrhotic liver (P.B202)


title: Hepatitis/cirrhotic liver (P.B198)


title: Hepatitis/cirrhotic liver (P.B200)


title: Hepatitis/cirrhotic liver (P.B196)


title: Hepatitis/cirrhotic liver (P.B190)


title: Hepatitis/cirrhotic liver (P.B194)


title: Hepatitis/cirrhotic liver (P.B182)


title: Hepatitis/cirrhotic liver (P.B188)


title: Hepatitis/cirrhotic liver (P.B186)


title: Hepatitis/cirrhotic liver (P.B172)


title: Hepatitis/cirrhotic liver (P.B170)


title: Hepatitis/cirrhotic liver (P.B192)


title: Hepatitis/cirrhotic liver (P.B174)


title: Hepatitis/cirrhotic liver (P.B178)


title: Hepatitis/cirrhotic liver (P.B152)


title: Hepatitis/cirrhotic liver (P.B160)


title: Hepatitis/cirrhotic liver (P.B156)


title: Hepatitis/cirrhotic liver (P.B134)


title: Hepatitis/cirrhotic liver (P.B150)


title: Hepatitis/cirrhotic liver (P.B180)


title: Hepatitis/cirrhotic liver (P.B128)


title: Hepatitis/cirrhotic liver (P.B148)


title: Hepatitis/cirrhotic liver (P.B083)


title: Hepatitis/cirrhotic liver (P.B079)


title: Hepatitis/cirrhotic liver (P.B018)


title: Hepatitis/cirrhotic liver (P.B081)


title: Hepatitis/cirrhotic liver (P.B026)


title: Hepatitis/cirrhotic liver (P.B075)


title: Hepatitis/cirrhotic liver (P.B071)


title: Hepatitis/cirrhotic liver (P.B036)


title: Hepatitis/cirrhotic liver (P.B032)


title: Hepatitis/cirrhotic liver (P.B008)


title: Hepatitis/cirrhotic liver (P.B006)


title: Healthy Control Sample PAX_CONT_3_C5

status: Public on Oct 01 2008

city: London

first: Graham

last: Heap

address: 4 Newark Street

country: United Kingdom

institute: QMUL

description: Healthy Control Sample PAX_CONT_3_C5

hyb_protocol: Complementary RNA was hybridized to Illumina HumanRef-8 v2 Whole Genome BeadChips

scan_protocol: Illumina BeadArray Reader, data was handled through Illumina BeadStudio Gene Expression module v3

data_processing: Quantile-quantile normalization.

source_name: Total RNA from peripheral blood RNA.

label_protocol: 2.5 ml of peripheral blood was collected into a PAXgene tube (Becton Dickinson, UK, 762165). PAXgene vials were chosen to prevent density gradient centrifugation, immortalization or in vitro cell culture artifacts changing mRNA profiles. PAXgene tubes were mixed gently and incubated at room temperature for two hours. After collection, tubes were frozen at -20 degrees Celsius for at least 24 hours followed by storage at -80 degrees Celsius. RNA was isolated using the PAXgene Blood RNA isolation kit (Qiagen, UK, 762174). RNA was quantified using the Nanodrop (Nanodrop Technologies, USA). Total RNA integrity was analyzed using an Agilent Bioanalyzer (Agilent Technologies, USA).

extract_protocol: PAXgene Blood RNA isolation kit protocol (Qiagen, UK, 762174)

tag: disease state

value: Healthy Control

value: Peripheral blood


title: Healthy Control Sample PAX_CONT_3_C6

description: Healthy Control Sample PAX_CONT_3_C6


title: Healthy Control Sample PAX_CONT_3_B8

description: Healthy Control Sample PAX_CONT_3_B8


title: Healthy Control Sample PAX_CONT_3_B7

description: Healthy Control Sample PAX_CONT_3_B7


title: Healthy Control Sample PAX_CONT_3_A11

description: Healthy Control Sample PAX_CONT_3_A11


title: Healthy Control Sample PAX_CONT_3_B9

description: Healthy Control Sample PAX_CONT_3_B9


title: Healthy Control Sample PAX_CONT_3_A4

description: Healthy Control Sample PAX_CONT_3_A4


title: Healthy Control Sample PAX_CONT_3_B4

description: Healthy Control Sample PAX_CONT_3_B4


title: Healthy Control Sample PAX_CONT_3_C4

description: Healthy Control Sample PAX_CONT_3_C4


title: Healthy Control Sample PAX_CONT_3_C3

description: Healthy Control Sample PAX_CONT_3_C3


title: Healthy Control Sample PAX_CONT_3_B1

description: Healthy Control Sample PAX_CONT_3_B1


title: Healthy Control Sample PAX_CONT_3_A12

description: Healthy Control Sample PAX_CONT_3_A12


title: Healthy Control Sample PAX_CONT_3_B5

description: Healthy Control Sample PAX_CONT_3_B5


title: Healthy Control Sample PAX_CONT_3_A10

description: Healthy Control Sample PAX_CONT_3_A10


title: Healthy Control Sample PAX_CONT_3_A6

description: Healthy Control Sample PAX_CONT_3_A6


title: Healthy Control Sample PAX_CONT_3_A3

description: Healthy Control Sample PAX_CONT_3_A3


title: Healthy Control Sample PAX_CONT_3_A5

description: Healthy Control Sample PAX_CONT_3_A5


title: Celiac Disease Sample 3_CAP153243

description: Celiac Disease Sample 3_CAP153243

value: Celiac Disease


title: Healthy Control Sample PAX_CONT_3_B3

description: Healthy Control Sample PAX_CONT_3_B3