title: ΔrpoZ_standard_biol.rep3

status: Public on Jan 30 2014

city: Turku

first: Taina

last: Tyystjarvi

address: Pharmacity/Itäinen Pitkäkatu 4 C, 6th floor

department: Biochemistry

country: Finland

institute: University of Turku

hyb_protocol: 500 ng Cy3-labelled sample was hybridized overnight at 65 °C following instruction of Agilent's Gene Expression Hybridization kit. Washes was performed using wash buffers from Gene Expression Wash Pack (Agilent) and following the manufacturers instructions.

scan_protocol: Slides were scanned on the Agilent Technologies Scanner (G2565CA) using scan profile AgilentHD_GX_1Color (Agilent HD 1- color gene expression microarrays).

data_processing: The scanned images were analyzed with Agilent's Feature Extraction program version 10.7.3. using  protocol GE1_107_Sep09 and Grid 016989_D_F_20070606. gProcessedSignal value and SystematicName were used to get normalized signal intensities. Data were normalized using the quantile-method.

organism: Synechocystis sp. PCC 6803

source_name: cells from mutant ΔrpoZ, standard growth conditions, biological replicate 3

label_protocol: Cyanine-3 (Cy3) labeled cDNA was prepared from 7 μg of total RNA using One-Color Microarray-Based Prokaryote Analysis (FairPlay III Labeling) Protocol Version 1.3 (August 2010) (Agilent). Agilent’s RNA Spike-In Kit was added to the samples allowing to monitor microarray workflow. Dye incorporation and cDNA concentration were measured with the NanoDrop ND-2000 Spectrophotometer.

growth_protocol: Cell were grown in BG-11 medium in standard growth conditions (continuous illumination at the PPFD of 40 µmol m-2s-1, 32°C, ambient CO2)

extract_protocol: RNA isolation was done as described previously (Eisenhut, M., von Wobeser, E.A., Jonas, L., Schubert, H., Ibelings, B.W., Bauwe, H. et al. (2007) Plant Physiol. 144: 1946-1959). RNA was purified and DNase treated using RNeasy mini kit (Qiagen).

value: ΔrpoZ

tag: phenotype

value: glucose tolerant

tag: treatment protocol

value: standard growth conditions


title: islets of pregnancy day 12.5, biological rep 1

status: Public on Feb 14 2014

type: RNA

city: Leuven

first: Leentje

last: Van Lommel

address: Herestraat 49 bus 901

department: Molecular cell biology

country: Belgium

institute: KULeuven

description: Gene expression data from islets of mice that were 12.5 day pregnant

hyb_protocol: Labeled DNA was hybridized to the array during 16h at 45°C

scan_protocol: The arrays were washed and stained in a fluidics station using the GeneChip hybridization, Wash end Stain kit (Affymetrix) and scanned using the Affymetrix 3000 GeneScanner.

data_processing: All image files were generated using the Affymetrix GeneChip command console (AGCC). The raw data were analyzed with RMA sketch using the standard settings for Gene 1.0 ST arrays of Expression Console in the AGCC software (affymetrix).

label: biotin

molecule: total RNA

organism: Mus musculus

source_name: mouse islets, C57bl6/J, P12.5

label_protocol: according to manufacturer’s manual 701880Rev4 (Affymetrix, Santa Clara, CA). Briefly, in the first cycle, double stranded cDNA was prepared with random hexamers tagged with a T7 promoter sequence followed by the generation of cRNA using the GeneChip WT Synthesis and Amplification kit (Affymetrix). cRNA concentration after cleanup was measured with the NanoDrop ND-1000 spectrophotometer (NanoDrop Technologies, DW). In the second cycle, sense oriented single-stranded DNA containing dUTP is generated and the concentration is, after cleanup, measured using the nanodrop. The cRNA is hydrolysed and the single stranded DNA is fragmented using uracil DNA glycosylase (UDG) and apurinic/apyrimidinic endonuclease 1 (APE1) (GeneChip WT terminal Labeling kit, Affymetrix). The quality of fragmentation (fragments should be between 40 and 70 nucleotides) is checked on the bioanalyzer (Agilent, Waldbronn, Germany). The fragmented DNA is labeled by terminal deoxynucleotidyl transferase (TDT) with the Affymetrix DNA Labeling reagent that is covalently linked to biotin (GeneChip WT terminal Labeling kit, Affymetrix).

extract_protocol: The absolute RNA microprep kit of Strategene was used to extract total RNA according to the manufacturer's instructions. The total RNA quantity and quality was determined using the NanoDrop ND-1000 spectrophotometer (NanoDrop Technologies, DW) and the 2100 Bioanalyzer (Agilent, Waldbronn, Germany), respectively. Total RNA profiles of all tested samples were similar with sharp 18S and 28S rRNA peaks on a flat baseline.

tag: genotype

value: wild type

tag: strain

tag: pregnancy day

tag: tissue

value: pancreatic islets


title: CS_standard_biol.rep4 (reanalysis)

source_name: cells from control strain, standard growth conditions, biological replicate 4

value: control strain


title: ΔrpoZ_standard_biol.rep1

source_name: cells from mutant ΔrpoZ, standard growth conditions, biological replicate 1


title: ΔrpoZ_standard_biol.rep2

source_name: cells from mutant ΔrpoZ, standard growth conditions, biological replicate 2


title: CS_standard_biol.rep1 (reanalysis)

source_name: cells from control strain, standard growth conditions, biological replicate 1


title: CS_standard_biol.rep3 (reanalysis)

source_name: cells from control strain, standard growth conditions, biological replicate 3


title: Patient67_non-arthritic cartilage

status: Public on Jul 01 2014

type: genomic

city: Vienna

first: Manuela

last: Hofner

address: Muthgasse 11/2

department: Molecular Diagnostics

country: Austria

institute: Austrian Institute of Technology - AIT

description: DNA-Methylation pattern analysis of arthritic knee cartilage, patient 67

hyb_protocol: Array hybridization was performed according to manufacturer`s instructions. For each array 5 µg of Cy3-labeled DNA were mixed with 50 µg of Human Cot-1 DNA in 1x Agilent Blocking Agent and 1x Agilent Hybridization Buffer in a total volume of 520 µl. Hybridization mixture was heated at 95°C for 3 minutes and incubated afterwards at 37°C for 30 minutes, then mixture was hybridized onto Agilent`s Human Promoter ChIP-on-chip microarrays (G4489A) for 40 hours at 65°C in a rotating Agilent hybridization oven (20 RPM). Agilent`s Human Promoter Microarray Set consists of 2 244k arrays (1 array per slide), therefore each patient sample was prepared in duplicate and hybridized onto one of the 2 different arrays. After hybridization microarrays were washed  5 minutes  at room temperature in Oligo aCGH/ChIP-on-chip Wash Buffer 1 (Agilent) and 5 minutes with 31°C prewarmed Oligo aCGH/ChIP-on-chip Wash Buffer 2 (Agilent). Then they were dried immediately by centrifugation (1000xg).

scan_protocol: Slides were scanned immediately after washing  on the Agilent Microarray scanner (G2505C) using one colour settings for 1x244k array slides (Scan area 61x21.6 mm; Scan resolution 5 µm; Dye channel set to Green and Green PMT set to 100%).

data_processing: Raw data analysis of scanned images was performed using the Feature Extraction Software 10.5.1 (Agilent) using protocol GE1_105_Dec08 and grid 014706_D_F_20080627 to receive background subtracted and spatially detrended signal intensities. Statistical analysis and data normalization was performed using the BRB-ArrayTools software 3.7.1, using the option of this program to combine both array data sets per sample (array A and array B) to one normalized data file. Values of Human Promoter ChIP-on-chip arrays were log2 transformed and a global normalization was used to median center the log intensity values within one experiment (Data provided in Matrix1_Norm. Data). For subsequent analysis only normalized data of a selection of 57138  target probes were included corresponding to generated DNA fragments (during methylation-specific enrichment procedure) providing no cut site for methylation-unspecific restriction enzymes  and at least one cut-site for one methylation-specific enzyme (Data provided in Matrix2_Selected Norm. Data).

molecule: genomic DNA

organism: Homo sapiens

source_name: knee cartilage, non-arthritic area

label_protocol: 4 µg of each DNA amplicon was labeled with Cyanine-3 (Cy3) in two separate reactions (2 µg/reaction) using the Agilent Genomic DNA Labeling Kit PLUS according to the manufacturer`s instructions. DNA yield and dye incorporation were determined using a NanoDrop ND-1000 Spectrophotometer (DNA yield > 5 µg per reaction, Specific activity > 3 pmol/µg).

extract_protocol: Cartilage samples were collected from patients undergoing total knee Arthroplasty due to severe osteoarthritis. Samples were harvested from macroscopic arthritic and non-arthritic areas of the medial or lateral femoral condyle with the use of an eight millimetres gouge in each patient`s knee. Cartilage samples (approximately 2 mg weight) were ground in liquid nitrogen and genomic DNA was isolated using the QIAamp DNA Micro Kit (QIAgen) according to the manufacturer`s instructions and quantified using  a Nanodrop ND-1000 Spectrophotometer. To mainly enrich methylated DNA a specific amplification protocol was performed based on combinations of different methylation-sensitive and -insensitive restriction digestion steps and a rolling circle amplification (RCA).

value: cartilage derived from medial/lateral femoral condyle

tag: disease

value: non-arthritic cartilage area

tag: gender

value: female


title: myoblasts treated with interferon gamma- rep4

status: Public on Feb 05 2014

city: Warsaw

first: Zofia

last: Wicik

state: mazovia

address: Pawinskiego 5

department: Department of Human Epigenetics

country: Poland

institute: Mossakowski Medical Research Center

description: Biological replicate 4 of 4. Control: myoblasts cells, untreated, harvested after 3 day of differentiation.

hyb_protocol: The cRNA was fragmented and hybridized to Agilent whole mouse genome oligonucleotide microarray (4 × 44K slide format) at 37 ºC for 17 hours (protocol Version 5.7, March 2008).

scan_protocol: After washing the slides were scanned with a DNA microarray Agilent Technologies Scanner G2505C US10353831  and images were processed with the Feature Extraction Software version 10.7.3.1 (Agilent Technologies).

data_processing: The scanned images were analyzed with Feature Extraction Software 10.7.3.1 (Agilent) using default parameters (protocol GE2_107_Sep09 and Grid: 026655_D_F_20100123) to obtain background subtracted and spatially detrended Processed Signal intensities. Features flagged in Feature Extraction as Feature Non-uniform outliers were excluded. Raw data were processed using GeneSpring 12GX (Agilent). Total detected entities were filtered by flags (present, marginal). In statistical analysis of differential gene expression unpaired t-test testing the null hypothesis of no differential expression between the control and experimental group was used. The statistical significance was set at P≤0.05. Moreover, the Benjamini-Hochberg FDR (False discovery rate) test with the significance level p≤0.05 was employed. Absolute fold change cut-off for ontological analyses  was 2. For interaction network analysis were used all entities with significant changes in expression.

source_name: C2C12 myoblasts- 3th day of differentiation in [10%HS+1ng IFNG per ml /24h/3d]

label_protocol: The total RNA (8 μg) was extracted, amplified and labeled in accordance with the protocol for Agilent Gene Expression oligo microarrays

growth_protocol: Cell cultures free of contamination were maintained in an exponential phase of growth in 10% FBS/DMEM, together with antibiotic-antimycotic mixture (Life Technologies), in controlled humidified air supplemented with 5% CO2, at 37oC. The growing medium was changed every other day.

extract_protocol: Total RNA was extracted and purified from C2C12 cells on the 3rd day after induction of differentiation using a Total RNA kit (A&A Biotechnology, Poland) according to the manufacturer’s protocol. The quality of the total RNA was examined by 2100 Bioanalyzer (Agilent).

treatment_protocol: Three days myogenic differentiation was induced when cells reached approximately 80% confluence, by switching to the medium containing 2% horse serum (HS) supplemented with IFN-γ (1 ng/ml).  According to our recent study this cytokine concentration affects IGF-I-dependent myogenesis and IGF-I signaling in C2C12 myoblasts (Wieteska-Skrzeczyńska and Grzelkowska-Kowalczyk, 2011a, b). To preserve the characteristics of the C2C12 cell line, the splitting of cells was done up to a maximum of 7 times.This experiment was conducted in quadruplicate.

tag: cell line

tag: age

value: 3th day of differentiation

tag: cell type

value: myoblasts

tag: treatment

value: 1ng/ ml IFNG

source_name: C2C12 myoblasts- 3th day of differentiation in [10%HS/24h/3d]

value: CTRL- untreated


title: myoblasts treated with interferon gamma- rep3

description: Biological replicate 3 of 4. Control: myoblasts cells, untreated, harvested after 3 day of differentiation.


title: CS_standard_biol.rep2 (reanalysis)

source_name: cells from control strain, standard growth conditions, biological replicate 2


title: islets of pregnancy day 12.5, biological rep 2


title: Aortic valve leaflet adult RFH 2

status: Public on Jan 11 2014

city: Madison

first: Ana

middle: Maria

last: Porras

state: WI

address: 1550 Engineering Drive #2153

department: Biomedical Engineering

country: USA

institute: UW-madison

description: Adult 2

hyb_protocol: After fragmentation, 10ug of aRNA were applied to each Affymetrix Porcine array. Samples were hybridized at 45C for 16 hours. Postprocessing of the GeneChips on the Affymetrix Fluidics 450 Station following the protocols and procedures outline for the Affymetrix Porcine array.

scan_protocol: GeneChips were scanned on a GC3000 G7 scanner. Data were extracted and processed using the Affymetrix Command Console v3.1.1.1229.

data_processing: Microarray data were analyzed using the open source statistical language R v2.15.2 and the libraries in the Bioconductor Project32. The raw expression values from the *.CEL files were background-corrected and normalized using the Robust Multi-array Analysis method.

organism: Sus scrofa

source_name: Aortic valve leaflet, RFH, adult

label_protocol: 400 ng of total RNA were labeled with the Ambion MessageAmp Premier IVT kit according to manufacturer's instructions.

growth_protocol: Swine were maintained on a standard chow diet.

extract_protocol: Leaflets were mechanically homogenized with a BulletBlend tube agitator according to manufacturer's instructions. Total RNA was isolated using the Qiagen RNeasy fibrous tissue spin-column kit following manufacturer's instructions.

treatment_protocol: Swine were stunned and euthanized by exsanguination. Within one hour of death, aortic valve leaflets were isolated and stored in RNAlater.

tag: breed

value: Rapacz Familial Hypercholesterolemic (RFH)

value: 2 years

tag: Sex

value: aortic valve leaflet


title: SK-Mel-147_mocktransfected_rep2

city: Leipzig

first: Animesh

last: Bhattacharya

state: Saxony

address: Johannisallee 30, MBFZ, Room no B-214

department: Dermatology

country: Germany

institute: University of Leipzig, Medical Faculty

description: Replicate 2

hyb_protocol: Standard Illumina hybridization protocol

scan_protocol: Arrays were scanned with an Illumina iScan microarray scanner. Bead level data preprocessing was done in Illumina GenomeStudio

data_processing: The data were normalised using quantile normalisation with IlluminaGUI in R. ANOVA was performed on the quantile normalized data of the distinctively treated cells. Differentially expressed genes were considered significant when adjusted p ≤ 0.01 (corrected for multiple testing by the Benjamini-Hochberg method). The genes which were both exclusively suppressed by miR-638 overexpression and de-repressed by miR-638 knockdown were considered for further validation. Finally, we reduced the number of candidates by considering only those genes with a total log10 fold change of 2 or more (sum of absolute fold changes). The data was processed and analyzed using the Bioconductor package lumi (Du et al., 2008) in the statistical programming environment R.

label: Biotin

source_name: SK-Mel-147 melanoma cells

label_protocol: Biotinylated cRNA were prepared with the TargetAmp™-Nano Labeling Kit for Illumina arrays

growth_protocol: SK-Mel-147 melanoma cells were cultured in growth medium containing Dulbecco's modified eagles medium(DMEM) containing 10% FCS and 1% L-glutamine with or without 1% Penicillin Streptomycin

extract_protocol: 48 hours post transfection, total RNA was extracted from the cells using miRVana microRNA isolation kit (Ambion, Life technologies, Darmstadt, germany)

treatment_protocol: SK-Mel-147 cells were cultured in complete growth medium (without antibiotics) and treated with the transfection reagent or transfected with a miRNA mimic or miR-638 mimic or miR-638 inhibitor (antagomiR).

value: control


title: myoblasts treated with interferon gamma- rep1

description: Biological replicate 1 of 4. Control: myoblasts cells, untreated, harvested after 3 day of differentiation.


title: myoblasts treated with interferon gamma- rep2

description: Biological replicate 2 of 4. Control: myoblasts cells, untreated, harvested after 3 day of differentiation.


title: SK-Mel-147_mocktransfected_rep1

description: Replicate 1


title: islets of pregnancy day 12.5, biological rep 3


title: Aortic valve leaflet adult RFH 4

description: Adult 4


title: 6639-1022315-miR125b #1 BM CD19+

status: Public on Jun 27 2014

first: Karen

middle: Dyer

last: Montgomery

address: 504 S Rosa Rd, Ste 101

department: Cytogenetics

institute: WiCell

hyb_protocol: NimbleGen Arrays User's Guide: CGH Analysis - Hybridization and Washing

scan_protocol: NimbleGen Arrays User's Guide: CGH Analysis - Two-Color Array Scanning utilizing the Axon 4000B GenePix Dual Laser Scanner

data_processing:
NimbleGen Arrays User's Guide: CGH Analysis - NimbleScan Data Analysis
infoQuant - cghFusion data analysis is based on the examination of unaveraged and/or 10X averaged data tracks. Settings for data analysis in infoQuant include an average log-ratio threshold of 0.2, a minimum aberration length of 5 probes, p-value of 0.001.  Additional analysis of this data may be performed using different ratio settings and different window averaging to enhance resolution.

source_name: miR125b #1 BM CD19b+

label_protocol: Add 1500ng genomic DNA to 80uL water for sonication. Sonicate samples to between 500bp-2000bp. Follow NimbleGen Arrays User's Guide: CGH Analysis - Sample Labeling

extract_protocol: Cells arrived pelleted and frozen in 1.5mL microcentrifuge tubes, which were stored at -80C until extraction. Incubate samples in 37C waterbath for ~5 min. until completely thawed. Follow Qiagen DNeasy Blood and Tissue Kit with RNase A digestion.

value: miR125b #1 BM CD19b+

value: Female

tag: sample type

value: B cell cancer

tag: ctr#

tag: dna#

source_name: healthy, wild type control

value: reference


title: MCPyV(+) Patient 4 replicate 2

status: Public on Jan 01 2014

city: Rennes

first: Nicolas

last: Mouchet

state: Bretagne

address: 2 Av du Professeur Leon Bernard

department: Institut genetique et developpement de Rennes

country: France

institute: CNRS UMR6290

description:
raw data_ch1:000417(130)_2b.txt
raw data_ch2:000417(130)_1b.txt
Normal Merkel Cells obtained from 3 liftings

hyb_protocol: the samples were subjected to a predefined PIQOR® Oncology Microarray (Miltenyi Biotec) and hybridization with a a-HybTM Hybridization Station was performed according to manufacturer's guidelines (Memorec Biotech)

scan_protocol: Scanned on an Agilent scanner

data_processing: LOWESS and Scale normalized, background subtracte. log2 of processed Red signal/processed Green signal. R version 2.15.1 was used.

source_name: MCPyV(+) Patient 4

label_protocol: 250ng of each cDNA were used for Cy3 (cDNA from Merkel cells) and Cy5 (cDNA from Merkel carcinoma cells)

extract_protocol: RNA extraction was performed using the PicoPure® RNA isolation kit following manufacturer's instructions

value: MCPyV(+) from flash frozen tumor

source_name: Total RNA from pooled of normal Merkel cell

value: pooled normal Merkel cells


title: Aortic valve leaflet adult RFH 3

description: Adult 3


title: MCPyV(+) Patient 4 replicate 3

description:
raw data_ch1:000417(131)_2b.txt
raw data_ch2:000417(131)_1b.txt
Normal Merkel Cells obtained from 3 liftings


title: MCPyV(+) Patient 4 replicate 1

description:
raw data_ch1:000417(129)_2b.txt
raw data_ch2:000417(129)_1b.txt
Normal Merkel Cells obtained from 3 liftings


title: MCPyV(+) Patient 3 replicate 1

description:
raw data_ch1:000417(126)_2b.txt
raw data_ch2:000417(126)_1b.txt
Normal Merkel Cells obtained from 3 liftings

source_name: MCPyV(+) Patient 3


title: MCPyV(+) Patient 2 replicate 3

description:
raw data_ch1:000417(125)_2b.txt
raw data_ch2:000417(125)_1b.txt
Normal Merkel Cells obtained from 3 liftings

source_name: MCPyV(+) Patient 2


title: Aortic valve leaflet juvenile RFH 3

description: Juvenile 3

source_name: Aortic valve leaflet, RFH, juvenile

value: 3 months


title: MCPyV(+) Patient 2 replicate 1

description:
raw data_ch1:000417(123)_2b.txt
raw data_ch2:000417(123)_1b.txt
Normal Merkel Cells obtained from 3 liftings


title: MCPyV(+) Patient 2 replicate 2

description:
raw data_ch1:000417(124)_2b.txt
raw data_ch2:000417(124)_1b.txt
Normal Merkel Cells obtained from 3 liftings


title: Aortic valve leaflet adult RFH 1

description: Adult 1


title: Aortic valve leaflet juvenile RFH 2

description: Juvenile 2


title: MCPyV(+) Patient 3 replicate 3

description:
raw data_ch1:000417(128)_2b.txt
raw data_ch2:000417(128)_1b.txt
Normal Merkel Cells obtained from 3 liftings


title: 6684-1022313-miR125b #2 BM CD11b+

source_name: miR125b #2 BM CD11b+

value: miR125b #2 BM CD11b+

value: myeloid cancer


title: MCPyV(+) Patient 3 replicate 2

description:
raw data_ch1:000417(127)_2b.txt
raw data_ch2:000417(127)_1b.txt
Normal Merkel Cells obtained from 3 liftings


title: MCPyV(+) Patient 1 replicate 1

description:
raw data_ch1:000417(122)_2b.txt
raw data_ch2:000417(122)_1b.txt
Normal Merkel Cells obtained from 3 liftings

source_name: MCPyV(+) Patient 1


title: Lgr5-High2

status: Public on Dec 04 2013

city: Singapore

first: Nick

last: Barker

address: 8A Biomedical Grove, Immunos

country: Singapore

institute: A*STAR Institute of Medical Biology

description: Gene expression data from ovarian surface epithelium cells expressing High-Lgr5EGFP levels

hyb_protocol: As per manufacturer's protocol, 2.5 ug of biotinylated cDNA were hybridized onto the Affymetrix Mouse GeneChip ST 2.0 arrays for 18 hr at 45C. GeneChips were then washed and stained in the Affymetrix Fluidics Station 450

scan_protocol: Scanning of GeneChips was performed on the Affymetrix GeneChip 7G 3000

data_processing: Expression data were processed using Affymetrix GeneChip Command Console (Affymetrix, Inc) to create raw data (.CEL) files, which were processed and on Affymetrix Expression Console software using default RMA Gene analysis settings (Affymetrix, Inc). Probe summarization (Robust Multichip Analysis, RMA), quality control analysis, and probe annotation were performed according to recommended guidelines (Expression Console Software, Affymetrix, Inc.).

source_name: OSE_high-Lgr5EGFP expression

label_protocol: Biotinylated cDNA were prepared following standard NuGen WT-Ovation Pico RNA Amplification system from 500pg-50 ng total RNA and Nugen Encore  Biotin Module

growth_protocol: Female mice of 8-12 weeks age were used for all samples

extract_protocol: Sorted cells were processed in Trizol for RNA extraction as per manufacturer's protocol.

value: female

value: 8-12 weeks

tag: genotype/variation

value: ovarian surface epithelium (OSE) cells

tag: lgr5 expression level

value: High (expressing high EGFP)


title: Aortic valve leaflet juvenile RFH 1

description: Juvenile 1

value: Rapacz Familial Hypercholesterolemic (RFH)


title: Lgr5-Low3

description: Gene expression data from ovarian surface epithelium cells expressing Low-Lgr5EGFP levels

source_name: OSE_low-Lgr5EGFP expression

value: Low (expressing low EGFP)


title: 6638-1022311-miR125b #1 BM CD11b+

source_name: miR125b #1 BM CD11b+

value: miR125b #1 BM CD11b+


title: SOBC1-1880

status: Public on Jul 31 2013

city: Los Angeles

first: Steve

last: Cole

state: CA

address: 11-934 Factor Bldg, UCLA

department: Medicine

institute: UCLA School of Medicine

description:
Illumina Human HT-12 BeadArray
6303230062_G.AVG_Signal

hyb_protocol: Standard Illumina hybridization protocol for gene expression profiling (carried out by UCLA Neuroscience Genomics Core).

scan_protocol: Standard Illumina scan protocol for gene expression profiling (carried out by UCLA Neuroscience Genomics Core).

data_processing: Raw probe intensity values and quantile-normalized gene expression values were generated by Illumina GenomeStudio software using Gene Expression module 1.1.1.  All available data are provided, with no additional filtering.

source_name: Healthy adult, Primary peripheral blood mononuclear cells (PBMCs)

label_protocol: Standard Illumina probe synthesis for gene expression profiling (carried out UCLA Neuroscience Genomics Core).

extract_protocol: Primary peripheral blood mononuclear cells were isolated and total RNA was extracted using Qiagen RNEasy.

tag: zhedonia

tag: zeudaimonia

tag: hedonia

tag: eudaimonia

tag: social

tag: psychological

tag: totalmhcsf

tag: flourishgroup

tag: brownpsychological

tag: brownsocial

tag: male

tag: white

tag: bmi

tag: alcohol

tag: smoke

tag: illnesssx


title: SOBC1-1722

description:
Illumina Human HT-12 BeadArray
6303230062_C.AVG_Signal

tag: age


title: SOBC1-1681

description:
Illumina Human HT-12 BeadArray
6247240069_A.AVG_Signal

tag: zhedonia


title: Lgr5-Low1

tag: gender

tag: genotype/variation

tag: cell type

tag: lgr5 expression level


title: Lgr5-High1


title: Lgr5-High3


title: SOBC1-1740

description:
Illumina Human HT-12 BeadArray
6247240069_K.AVG_Signal

tag: zeudaimonia

tag: hedonia

tag: eudaimonia

tag: social

tag: psychological


title: SOBC1-1900

description:
Illumina Human HT-12 BeadArray
6247240074_A.AVG_Signal

value: Missing

tag: totalmhcsf

tag: flourishgroup

tag: brownpsychological

tag: brownsocial

tag: male


title: SOBC1-1683

description:
Illumina Human HT-12 BeadArray
6303230062_D.AVG_Signal

tag: white

tag: bmi

tag: alcohol

tag: smoke

tag: illnesssx


title: SOBC1-1480

description:
Illumina Human HT-12 BeadArray
6247240051_H.AVG_Signal

tag: zhedonia

tag: age


title: SOBC1-1720

description:
Illumina Human HT-12 BeadArray
6247240069_E.AVG_Signal

tag: zeudaimonia


title: SOBC1-1684

description:
Illumina Human HT-12 BeadArray
6303230062_E.AVG_Signal

tag: hedonia


title: SOBC1-1580

description:
Illumina Human HT-12 BeadArray
6247240061_K.AVG_Signal

tag: eudaimonia


title: SOBC1-1600

description:
Illumina Human HT-12 BeadArray
6303230062_B.AVG_Signal

tag: social


title: SOBC1-1345

description:
Illumina Human HT-12 BeadArray
6247240055_J.AVG_Signal

tag: psychological


title: SOBC1-1440

description:
Illumina Human HT-12 BeadArray
6247240069_I.AVG_Signal

tag: totalmhcsf


title: SOBC1-1721

description:
Illumina Human HT-12 BeadArray
6247240069_F.AVG_Signal

tag: flourishgroup


title: SOBC1-1680

description:
Illumina Human HT-12 BeadArray
6303230062_A.AVG_Signal

tag: brownpsychological


title: SOBC1-1441

description:
Illumina Human HT-12 BeadArray
6247240055_D.AVG_Signal

tag: brownsocial


title: SOBC1-1344

description:
Illumina Human HT-12 BeadArray
6247240069_B.AVG_Signal

tag: male


title: SOBC1-1601

description:
Illumina Human HT-12 BeadArray
6247240051_F.AVG_Signal

tag: white


title: SOBC1-1333

description:
Illumina Human HT-12 BeadArray
6247240052_C.AVG_Signal

tag: bmi


title: SOBC1-1760

description:
Illumina Human HT-12 BeadArray
6247240069_L.AVG_Signal

tag: alcohol


title: SOBC1-1422

description:
Illumina Human HT-12 BeadArray
6247240061_L.AVG_Signal

tag: smoke


title: SOBC1-1306

description:
Illumina Human HT-12 BeadArray
6247240055_I.AVG_Signal

tag: illnesssx


title: SOBC1-1329

description:
Illumina Human HT-12 BeadArray
6247240061_A.AVG_Signal

tag: zhedonia


title: SOBC1-1328

description:
Illumina Human HT-12 BeadArray
6247240061_G.AVG_Signal

tag: age


title: SOBC1-1326

description:
Illumina Human HT-12 BeadArray
6247240052_I.AVG_Signal

tag: zeudaimonia


title: SOBC1-1288

description:
Illumina Human HT-12 BeadArray
6247240061_J.AVG_Signal

tag: hedonia


title: SOBC1-1293

description:
Illumina Human HT-12 BeadArray
6247240061_C.AVG_Signal

tag: eudaimonia


title: SOBC1-1292

description:
Illumina Human HT-12 BeadArray
6247240061_F.AVG_Signal

tag: social


title: SOBC1-1273

description:
Illumina Human HT-12 BeadArray
6247240069_C.AVG_Signal

tag: psychological


title: SOBC1-1294

description:
Illumina Human HT-12 BeadArray
6247240061_I.AVG_Signal

tag: totalmhcsf


title: SOBC1-1277

description:
Illumina Human HT-12 BeadArray
6247240052_J.AVG_Signal

tag: flourishgroup


title: SOBC1-1264

description:
Illumina Human HT-12 BeadArray
6247240055_F.AVG_Signal

tag: brownpsychological


title: SOBC1-1287

description:
Illumina Human HT-12 BeadArray
6247240069_G.AVG_Signal

tag: brownsocial


title: SOBC1-1286

description:
Illumina Human HT-12 BeadArray
6247240069_J.AVG_Signal

tag: male


title: SOBC1-1300

description:
Illumina Human HT-12 BeadArray
6247240055_B.AVG_Signal

tag: white


title: SOBC1-1271

description:
Illumina Human HT-12 BeadArray
6247240051_K.AVG_Signal

tag: bmi


title: SOBC1-1285

description:
Illumina Human HT-12 BeadArray
6247240051_D.AVG_Signal

tag: alcohol


title: SOBC1-1299

description:
Illumina Human HT-12 BeadArray
6247240074_L.AVG_Signal

tag: smoke


title: SOBC1-1262

description:
Illumina Human HT-12 BeadArray
6247240055_H.AVG_Signal

tag: illnesssx


title: SOBC1-1305

description:
Illumina Human HT-12 BeadArray
6247240074_E.AVG_Signal

tag: zhedonia


title: SOBC1-1252

description:
Illumina Human HT-12 BeadArray
6247240051_B.AVG_Signal

tag: age


title: SOBC1-1289

description:
Illumina Human HT-12 BeadArray
6303230062_F.AVG_Signal

tag: zeudaimonia


title: SOBC1-1297

description:
Illumina Human HT-12 BeadArray
6247240055_L.AVG_Signal

tag: hedonia


title: SOBC1-1283

description:
Illumina Human HT-12 BeadArray
6247240051_A.AVG_Signal

tag: eudaimonia


title: SOBC1-1259

description:
Illumina Human HT-12 BeadArray
6247240051_I.AVG_Signal

tag: social


title: SOBC1-1256

description:
Illumina Human HT-12 BeadArray
6247240051_J.AVG_Signal

tag: psychological


title: SOBC1-1263

description:
Illumina Human HT-12 BeadArray
6247240074_I.AVG_Signal

tag: totalmhcsf


title: SOBC1-1255

description:
Illumina Human HT-12 BeadArray
6247240051_E.AVG_Signal

tag: flourishgroup


title: SOBC1-1343

description:
Illumina Human HT-12 BeadArray
6247240055_K.AVG_Signal

tag: brownpsychological


title: SOBC1-1260

description:
Illumina Human HT-12 BeadArray
6247240052_E.AVG_Signal

tag: brownsocial


title: SOBC1-1239

description:
Illumina Human HT-12 BeadArray
6247240055_E.AVG_Signal

tag: male


title: SOBC1-1247

description:
Illumina Human HT-12 BeadArray
6247240074_B.AVG_Signal

tag: white


title: SOBC1-1246

description:
Illumina Human HT-12 BeadArray
6247240074_G.AVG_Signal

tag: bmi


title: SOBC1-1231

description:
Illumina Human HT-12 BeadArray
6247240052_K.AVG_Signal

tag: alcohol


title: SOBC1-1198

description:
Illumina Human HT-12 BeadArray
6247240074_K.AVG_Signal

tag: smoke


title: SOBC1-1201

description:
Illumina Human HT-12 BeadArray
6247240074_D.AVG_Signal

tag: illnesssx


title: SOBC1-1225

description:
Illumina Human HT-12 BeadArray
6247240052_A.AVG_Signal

tag: zhedonia


title: SOBC1-1237

description:
Illumina Human HT-12 BeadArray
6247240069_H.AVG_Signal

tag: age


title: SOBC1-1241

description:
Illumina Human HT-12 BeadArray
6247240061_E.AVG_Signal

tag: zeudaimonia


title: SOBC1-1197

description:
Illumina Human HT-12 BeadArray
6247240055_A.AVG_Signal

tag: hedonia


title: SOBC1-1195

description:
Illumina Human HT-12 BeadArray
6247240052_L.AVG_Signal

tag: eudaimonia


title: SOBC1-1232

description:
Illumina Human HT-12 BeadArray
6247240055_C.AVG_Signal

tag: social


title: SOBC1-1245

description:
Illumina Human HT-12 BeadArray
6247240061_B.AVG_Signal

tag: psychological


title: SOBC1-1196

description:
Illumina Human HT-12 BeadArray
6247240052_G.AVG_Signal

tag: totalmhcsf


title: SOBC1-1235

description:
Illumina Human HT-12 BeadArray
6247240051_C.AVG_Signal

tag: flourishgroup


title: SOBC1-1220

description:
Illumina Human HT-12 BeadArray
6247240051_L.AVG_Signal

tag: brownpsychological


title: SOBC1-1190

description:
Illumina Human HT-12 BeadArray
6247240074_C.AVG_Signal

tag: brownsocial


title: SOBC1-1228

description:
Illumina Human HT-12 BeadArray
6247240061_H.AVG_Signal

tag: male


title: SOBC1-1193

description:
Illumina Human HT-12 BeadArray
6247240074_F.AVG_Signal

tag: white


title: SOBC1-1194

description:
Illumina Human HT-12 BeadArray
6247240052_B.AVG_Signal

tag: bmi


title: SOBC1-1234

description:
Illumina Human HT-12 BeadArray
6247240074_J.AVG_Signal

tag: alcohol


title: SOBC1-1186

description:
Illumina Human HT-12 BeadArray
6247240052_H.AVG_Signal

tag: smoke


title: SOBC1-1199

description:
Illumina Human HT-12 BeadArray
6247240051_G.AVG_Signal

tag: illnesssx


title: SOBC1-1188

description:
Illumina Human HT-12 BeadArray
6247240052_F.AVG_Signal

tag: zhedonia


title: SOBC1-1223

description:
Illumina Human HT-12 BeadArray
6247240069_D.AVG_Signal

tag: age


title: SOBC1-1189

description:
Illumina Human HT-12 BeadArray
6247240061_D.AVG_Signal

tag: zeudaimonia


title: SOBC1-1192

description:
Illumina Human HT-12 BeadArray
6247240052_D.AVG_Signal

tag: hedonia


title: SOBC1-1182

description:
Illumina Human HT-12 BeadArray
6247240074_H.AVG_Signal

tag: eudaimonia


title: SOBC1-1185

description:
Illumina Human HT-12 BeadArray
6247240055_G.AVG_Signal

tag: social


title: HF vs LIM - 4 (dye-swap)

status: Public on Jun 16 2013

description: replicate 4 of 4. control- LM mammary gland

hyb_protocol: The cRNA was fragmented and hybridized to Agilent whole mouse genome oligonucleotide microarray (4 × 44K slide format) at 37 ºC for 17 hours.

scan_protocol: After washing the slides were scanned with a DNA microarray scanner (Agilent Technologies) and images were processed with the Feature Extraction Software version (Agilent Technologies).

data_processing:
The scanned images were analyzed with Feature Extraction Software  (Agilent) using default parameters (protocol:GE2_1010_Sep10  and Grid:023647_D_F_20121015 ) to obtain background subtracted and spatially detrended Processed Signal intensities. Features flagged in Feature Extraction as Feature Non-uniform outliers were excluded. Raw data were processed using GeneSpring GX 12 (Agilent):
#Entitylist : Filtered on Flags [Detected, Not Detected]
#corrected p-value cut-off:0.05
#Selected Test : T Test Against Zero
#p-value computation: Asymptotic
#Multiple Testing Correction: Benjamini-Hochberg
#Fold change cut-off 1.3
# Technology: Agilent.TwoColor.23647

organism: Bos taurus

source_name: pooled quarters of mammary glands form 10 heifers

label_protocol: 1µg of sample was spiked with a set of 10 positive control transcripts (Agilent Technologies), converted to double stranded cDNA in a reverse transcription reaction, amplified and labeled with an in vitro transcription reaction according to the manufacturer’s protocol (Agilent Technologies). Microarrays US10353831_252364710504_S01_GE2_1010_Sep10_1_3 and   US10353831_252364710504_S01_GE2_1010_Sep10_1_4.txt are dye-swaps.

extract_protocol: Tissue samples of mammary gland were obtained from 10 HF and 10 LIM heifers subjected to slatery. The samples were snap frozen in RNA-later (Sigma Aldrich) and stored in -80ºC.  Two groups of samples were created, one consisted tissue obtained from dairy heifers ( Holstein-Fresian) second group consisted samples taken from beef heifers ( Limousin breed). Each group contained of 10 samples , respectively. Total RNA was extracted from the cells with RNeasy (Qiagen). The quality of the total RNA was examined by 2100 Bioanalyzer (Agilent).

tag: gender

value: heifer

value: 20 months

tag: breed

value: Limousin

tag: disease state

value: healthy

value: Holstein-Fresian


title: HF vs LIM - 2

description: replicate 2 of 4. control- LM mammary gland


title: HF vs LIM - 1

description: replicate 1 of 4. control- LM mammary gland


title: HF vs LIM - 3 (dye-swap)

description: replicate 3 of 4. control- LM mammary gland


title: Pancreas Nupr1 (+/+) Kras-G12D, rep 1

status: Public on Jul 01 2013

city: Quebec

first: Ezequiel

middle: L

last: Calvo

state: Quebec

address: 2705 Boul. Laurier

department: Molecular Endocrinilogy

country: Canada

institute: CRCHUL

description:
T23-81
Pancreatic tissue from C57BL/6 mice bearing a homozygous deletion of exon 2 of the Nupr1 gene (+/+) and Kra-G12D mutation.

hyb_protocol: The cRNA hybridization cocktail was incubated overnight at 45°C while rotating in a hybridization oven. After 16 h of hybridization, the cocktail was removed and the arrays were washed and stained in an Affymetrix GeneChip Fluidics Station 450, according to the Affymetrix-recommended protocol (http://media.affymetrix.com/support/downloads/manuals/wt_sensetarget_label_manual.pdf).

scan_protocol: Chips were scanned with a GeneChip scanner 3000 G7 (Affymetrix).

data_processing: Background subtraction and normalization of probe set intensities were performed using the method of Robust Multiarray Analysis (RMA) described by Irizarry et al. (Irizarry et al, 2003).To normalize the data we use the Partek Genomics Suite, version 6.5 (Partek Inc., St. Louis, MO).

source_name: Pancreatic tissue from C57BL/6 Nupr1 (+/+) mice bearing a Kra-G12D mutation

label_protocol: DNA microarray analyses were carried out with Affymetrix Mouse Gene 1.0 ST arrays according to the Affymetrix standard protocol. Briefly, total RNA (200 ng per sample) was labeled using the Affymetrix GeneChip® WT cDNA Synthesis and Amplification Kit protocol, and hybridized to the arrays as described by the manufacturer (Affymetrix, Santa Clara, CA).

growth_protocol: Five-week-old C57BL/6 mice littermate control (+/+) and wild-type mice (-/-) were used. Mice were kept within the Experimental Animal House of the Centre de Cancérologie de Marseille (CRCM) pole Luminy, following institutional guidelines.

extract_protocol: Total RNAs were extracted using Trizol reagent (Invitrogen, Burlington, ON, Canada). Total RNA was purified on RNeasy mini kit columns (Qiagen, Mississauga, ON, Canada).

tag: strain/background

tag: genotype

value: Nupr1 (+/+) Kras-G12D

tag: tissue

value: pancreas


title: Pancreas Nupr1 (+/+) Kras-G12D, rep 2

description:
T23-84
Pancreatic tissue from C57BL/6 mice bearing a homozygous deletion of exon 2 of the Nupr1 gene (+/+) and Kra-G12D mutation.


title: Pancreas Nupr1 (+/+) Kras-G12D, rep 3

description:
T23-89
Pancreatic tissue from C57BL/6 mice bearing a homozygous deletion of exon 2 of the Nupr1 gene (+/+) and Kra-G12D mutation.


title: Pancreas Nupr1 -/-  Kras-G12D, rep 2

description:
T23-77
Pancreatic tissue from C57BL/6 Nupr1 (-/-) mice bearing a Kra-G12D mutation.

value: Nupr1 -/-  Kras-G12D


title: Pancreas Nupr1 -/-  Kras-G12D, rep 1

description:
T21-69
Pancreatic tissue from C57BL/6 Nupr1 (-/-) mice bearing a Kra-G12D mutation.


title: Normal Skin_Sample 14.10

status: Public on May 01 2013

city: Houston

first: Lawrence

middle: N

last: Kwong

state: TX

address: 1901 East Rd

institute: UT MD Anderson Cancer Center

hyb_protocol: Following fragmentation, 10 ug of cRNA were hybridized for 16 hr at 45C on a GeneChip Human Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.

scan_protocol: GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G2500A.

data_processing: Raw image files were converted to probe set data (.cel files) in Microarray Suite (MAS 5.0). The probe set data files were normalized together, and expression values were determined, using the Robust Multi-chip Average (RMA) method as implemented in RMAExpress (Bolstad/Berkeley).

source_name: Normal Skin, Sample 14.10

label_protocol: Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 10 ug total RNA.

extract_protocol: Trizol extraction of total RNA was performed according to the manufacturer's instructions.

tag: tissue type

value: Normal Skin

tag: body-site

value: breast

tag: diagnosis

value: normal skin


title: Normal Skin_Sample 101.1

source_name: Normal Skin, Sample 101.1

tag: % melanocytes

tag: % inflammatory cells

tag: % keratinocytes

value: right forearm

value: Lentigo simplex/normal skin


title: Normal Epithelial Melanocytes_Sample 98.1

source_name: Normal Epithelial Melanocytes, Sample 98.1

value: Normal Epithelial Melanocytes

value: foreskin


title: Lgr5-Low2

description: Gene expression data from ovarian surface epithelium cells expressing Low-Lgr5EGFP levels

value: female

tag: age

value: 8-12 weeks

tag: genotype/variation

tag: cell type

value: ovarian surface epithelium (OSE) cells

tag: lgr5 expression level

value: Low (expressing low EGFP)


title: Nevus_Sample 101.5

source_name: Nevus, Sample 101.5

value: Nevus

tag: patient id

value: Halo-nevus, compound-type

tag: subtype

value: B, small epithelioid


title: Normal Skin_Sample 14.9

source_name: Normal Skin, Sample 14.9


title: Normal Skin_Sample 13.4

source_name: Normal Skin, Sample 13.4


title: Nevus_Sample 101.4

source_name: Nevus, Sample 101.4

value: melanocytic nevus, compound-type


title: Nevus_Sample 101.2

source_name: Nevus, Sample 101.2

value: melanocytic nevus, junctional-type

value: A, dendritic


title: Normal Skin_Sample 99.1

source_name: Normal Skin, Sample 99.1

value: Normal Skin


title: Nevus_Sample 87.6

source_name: Nevus, Sample 87.6


title: Nevus_Sample 100.4

source_name: Nevus, Sample 100.4


title: Normal Skin_Sample 14.8

source_name: Normal Skin, Sample 14.8

value: breast


title: Normal Skin_Sample 14.7

source_name: Normal Skin, Sample 14.7

value: normal skin


title: Nevus_Sample 100.1

source_name: Nevus, Sample 100.1


title: Nevus_Sample 104.1

source_name: Nevus, Sample 104.1

value: C, Schwann-cell type


title: Primary Melanoma_Sample 90.5

source_name: Primary Melanoma, Sample 90.5

value: Primary Melanoma

tag: % melanoma cells

tag: % other cells

tag: necrosis (% of total area)

value: left food

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

value: caucasian

tag: clinical stage

value: 2 B new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

value: 12/99 LNN ing. left; 9/00 LNN cervical left; 1/02 LNN right axilla; 4/02 brain

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

tag: past malignant tumors?

tag: last clinical status

value: 2002, death, MM-related

tag: ulceration

value: Yes

tag: clark's

value: IV

tag: breslow thickness

tag: rgp

tag: vgp

tag: vgp type

value: Epithelioid

tag: precursor

value: No

tag: mitotic rate

tag: tils

value: Absent

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites

tag: comments

value: type:nodular vs. superficial spreading


title: Primary Melanoma_Sample 89.6

source_name: Primary Melanoma, Sample 89.6

tag: tissue type

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: right lower leg

tag: date of resection

tag: age at time of resection

tag: gender

value: female

tag: race

tag: clinical stage

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: 6/92 liver, LNN

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Jul 92, death, MM-related

tag: type

value: SSM, sec. nodular

tag: ulceration size

value: Non-brisk


title: Primary Melanoma_Sample 90.3

source_name: Primary Melanoma, Sample 90.3

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

value: right forearm

value: caucasian

value: 1 A new AJCC

tag: past malignant tumors?

tag: last clinical status

value: Mar 02, alive, NED

value: SSM

tag: ulceration

tag: clark's

value: III

tag: breslow thickness

tag: rgp

tag: vgp

tag: vgp type

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 89.4

source_name: Primary Melanoma, Sample 89.4

tag: tissue type

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: backside

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: 2 B new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

value: 6/96 lung, LNN

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

value: adrenal adenoma

value: 1996, death, MM-related

tag: type

value: IV

tag: ulceration size

value: Yes

value: Epithelioid


title: Nevus_Sample 88.3

source_name: Nevus, Sample 88.3

tag: tissue type

value: Nevus

tag: patient id

tag: % melanocytes

tag: % keratinocytes

tag: diagnosis

value: melanocytic nevus, compound-type

tag: subtype

value: B, small epithelioid


title: Primary Melanoma_Sample 8.3

source_name: Primary Melanoma, Sample 8.3

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: scalp

tag: date of resection

tag: age at time of resection

value: caucasian

value: 3 A new AJCC

value: 4/94 liver

tag: past malignant tumors?

tag: last clinical status

value: Apr 94, death, MM-related

tag: ulceration

tag: clark's

tag: breslow thickness

tag: rgp

tag: vgp

tag: vgp type

tag: precursor

value: No

tag: mitotic rate

tag: tils

value: Non-brisk

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 87.3

source_name: Primary Melanoma, Sample 87.3

tag: tissue type

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: left lower leg

tag: date of resection

tag: gender

value: female

tag: race

tag: clinical stage

value: 2 A new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

value: 7/95 cutis; 8/97 cutis; 9/97 LNN; 12/97 LNN [recurrence]; 5/98 skin; 7/98 LNN [recurrence] + skin; 7/98 liver, lung; 11/98 LNN [recurrence]

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

value: Feb 99, death, MM-related

tag: type

value: SSM

value: V

tag: ulceration size

value: Epithelioid and Spindled

value: LCDN


title: Primary Melanoma_Sample 89.5

source_name: Primary Melanoma, Sample 89.5

tag: tissue type

value: Primary Melanoma

value: left food

tag: age at time of resection

value: caucasian

value: 2 B new AJCC

tag: past malignant tumors?

tag: last clinical status

value: Nov 02, alive, NED

tag: ulceration

tag: clark's

value: III/IV

tag: breslow thickness

tag: rgp

value: Yes

tag: vgp

tag: vgp type

value: Epithelioid

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 78.2

source_name: Primary Melanoma, Sample 78.2

tag: tissue type

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: right food

tag: date of resection

tag: gender

value: female

tag: race

tag: clinical stage

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Feb 02, death, MM-unrelated

tag: type

value: Acral Lentiginous

value: No

tag: ulceration size

value: Non-brisk


title: Primary Melanoma_Sample 89.2

source_name: Primary Melanoma, Sample 89.2

tag: tissue type

value: neck

tag: age at time of resection

value: male

value: 3 B new AJCC

value: no

value: FI

tag: past malignant tumors?

tag: last clinical status

value: Mar 02, death, MM-related

value: SSM

tag: ulceration

tag: clark's

value: III

tag: breslow thickness

tag: rgp

tag: vgp

tag: vgp type

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 79.3

source_name: Primary Melanoma, Sample 79.3

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: backside

tag: date of resection

tag: gender

tag: race

value: caucasian

tag: clinical stage

value: 1 B new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Jun 01, alive, NED

tag: type

tag: ulceration size


title: Primary Melanoma_Sample 90.6

source_name: Primary Melanoma, Sample 90.6

tag: tissue type

value: abdomen

tag: age at time of resection

value: female

value: 2 A new AJCC

tag: past malignant tumors?

tag: last clinical status

value: Nov 02, alive, NED

value: Nodular

tag: ulceration

tag: clark's

tag: breslow thickness

tag: rgp

tag: vgp

value: Yes

tag: vgp type

value: Epithelioid

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 71.5

source_name: Primary Melanoma, Sample 71.5

tag: tissue type

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: chest

tag: date of resection

tag: gender

value: male

tag: race

tag: clinical stage

tag: tnm status

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Jan 03, alive, NED

tag: type

value: No

tag: ulceration size

value: Non-brisk


title: Primary Melanoma_Sample 72.4

source_name: Primary Melanoma, Sample 72.4

tag: tissue type

value: Primary Melanoma

value: backside

tag: age at time of resection

value: FI

tag: past malignant tumors?

tag: last clinical status

value: SSM

tag: ulceration

tag: clark's

value: III

tag: breslow thickness

tag: rgp

tag: vgp

tag: vgp type

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 72.2

source_name: Primary Melanoma, Sample 72.2

tag: tissue type

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: scalp

tag: date of resection

tag: gender

value: female

tag: race

value: caucasian

tag: clinical stage

value: 3 A new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: 9/99 satellite mets , 7/01 LNN left cervical/supraclavicular, 10/01 LNN right cervical/axilla, 2/02 LNN left cervical, s.c. left cervical and supraclavicular, 7/02 colon, coecum, liver; 8/02 lungs

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Okt 02, death, MM-related

tag: type

value: SSM, sec. nodular

value: V

tag: ulceration size


title: Primary Melanoma_Sample 20.1

source_name: Primary Melanoma, Sample 20.1

tag: tissue type

value: left thigh

tag: age at time of resection

value: male

value: 2 A new AJCC

value: no

value: 8/97 LNN left inguinal; 8/98 liver; 12/98 brain

value: SSM right lumb 9/97

tag: past malignant tumors?

tag: last clinical status

value: Mai 01, death, MM-related

tag: ulceration

tag: clark's

value: IV

tag: breslow thickness

tag: rgp

value: Yes

tag: vgp

tag: vgp type

value: Epithelioid

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 74.5

source_name: Primary Melanoma, Sample 74.5

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: backside

tag: date of resection

tag: gender

tag: race

tag: clinical stage

value: 1 A new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

value: Feb 00, alive, NED

tag: type

value: SSM

value: No

value: II

tag: ulceration size

value: Partial


title: Primary Melanoma_Sample 15.5

source_name: Primary Melanoma, Sample 15.5

tag: tissue type

value: right lower leg

tag: age at time of resection

value: male

value: caucasian

value: 2 A new AJCC

tag: past malignant tumors?

tag: last clinical status

value: Nov 01, alive, NED

tag: ulceration

tag: clark's

tag: breslow thickness

tag: rgp

tag: vgp

tag: vgp type

value: Spindled

tag: precursor

value: DN FOC

tag: mitotic rate

tag: tils

value: Non-brisk

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 106.3

source_name: Primary Melanoma, Sample 106.3

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: left lower leg

tag: date of resection

tag: gender

value: female

tag: race

tag: clinical stage

tag: tnm status

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Aug 02, alive, NED

tag: type

value: III

tag: ulceration size

value: Yes

value: Epithelioid

value: DN


title: Primary Melanoma_Sample 106.2

source_name: Primary Melanoma, Sample 106.2

tag: tissue type

value: left upper arm

tag: age at time of resection

value: 1 A new AJCC

value: FI

tag: past malignant tumors?

tag: last clinical status

value: Sep 03, alive, NED

value: SSM

tag: ulceration

value: No

tag: clark's

value: II

tag: breslow thickness

tag: rgp

tag: vgp

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 107.5

source_name: Primary Melanoma, Sample 107.5

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: right shoulder

tag: date of resection

tag: gender

value: male

tag: race

value: caucasian

tag: clinical stage

value: 1 B new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

tag: type

value: IV

tag: ulceration size

tag: vgp type

value: Non-brisk


title: Primary Melanoma_Sample 103.3

source_name: Primary Melanoma, Sample 103.3

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

value: right forearm

tag: age at time of resection

value: 2 A new AJCC

value: no

tag: past malignant tumors?

tag: last clinical status

value: Okt 02, death, MM-unrelated

tag: ulceration

tag: clark's

value: III

tag: breslow thickness

tag: rgp

tag: vgp

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 104.6

source_name: Primary Melanoma, Sample 104.6

tag: tissue type

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: abdomen

tag: date of resection

tag: gender

tag: race

tag: clinical stage

value: 2 B new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: yes, progressive disease

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

value: Okt 01, death, MM-related

tag: type

value: SSM, sec. nodular

value: Yes

value: V

tag: vgp type

value: Epithelioid and Spindled

tag: comments

value: no further clinical data available


title: Primary Melanoma_Sample 103.1

source_name: Primary Melanoma, Sample 103.1

tag: tissue type

tag: % melanoma cells

value: left food

tag: age at time of resection

value: female

value: caucasian

value: colon CA 1996

tag: past malignant tumors?

tag: last clinical status

value: Aug 00, death, MM-unrelated

value: Acral Lentiginous

tag: ulceration

tag: clark's

value: IV

tag: breslow thickness

tag: ulceration size

tag: rgp

tag: vgp

value: Epithelioid

tag: precursor

value: No

tag: mitotic rate

tag: tils

value: Absent

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Primary Melanoma_Sample 104.5

source_name: Primary Melanoma, Sample 104.5

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: neck

tag: date of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: 1 A new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

value: yes, liposarcoma 8/99

value: liposarcoma

value: Nov 01, death, MM-unrelated

tag: type

value: SSM

value: III

value: Non-brisk


title: Primary Melanoma_Sample 102.6

source_name: Primary Melanoma, Sample 102.6

value: backside

tag: age at time of resection

value: female

value: caucasian

value: 1 B new AJCC

tag: past malignant tumors?

tag: last clinical status

value: Feb 03, alive, NED

tag: ulceration

tag: clark's

tag: breslow thickness

tag: ulceration size

tag: rgp

value: Yes

tag: vgp

tag: vgp type

tag: precursor

tag: mitotic rate

value: Cannot Evaluate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites

tag: comments

value: tumor cells could be high as 50%


title: Primary Melanoma_Sample 103.5

source_name: Primary Melanoma, Sample 103.5

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: right lower leg

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

tag: clinical stage

value: 1 A new AJCC

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Mai 02, alive, NED

tag: type

value: No

value: Epithelioid

value: CCN

value: 50% melanoma cells, 50% nevus cells


title: Primary Melanoma_Sample 107.4

source_name: Primary Melanoma, Sample 107.4

tag: tissue type

tag: % melanoma cells

value: scalp

value: male

value: 2 A new AJCC

value: no

value: FI

tag: last clinical status

value: Jun 96, alive, NED

value: SSM

tag: ulceration

tag: clark's

value: IV

tag: breslow thickness

tag: ulceration size

tag: rgp

tag: vgp

tag: vgp type

value: Spindled

tag: precursor

tag: mitotic rate

tag: tils

value: Non-brisk

tag: neural invasion

tag: vascular

tag: regression

value: Partial

tag: microsatellites

tag: comments

value: Breslow:1,2 vs. 3,0


title: Primary Melanoma_Sample 102.5

source_name: Primary Melanoma, Sample 102.5

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: backside

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

value: caucasian

tag: clinical stage

tag: tnm status

tag: prior ctx, rtx, itx

tag: subsequent metastasis

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Sep 03, alive, NED

tag: type

value: SSM, sec. nodular

value: Yes


title: Primary Melanoma_Sample 106.1

source_name: Primary Melanoma, Sample 106.1

tag: tissue type

tag: % melanoma cells

value: left lower leg

value: female

value: 1 A new AJCC

value: 10/98 LNN left inguinal, 3/99 brain, suspected lung mets

tag: last clinical status

value: 1999, death, MM-related

tag: ulceration

value: No

tag: clark's

tag: breslow thickness

tag: ulceration size

tag: rgp

tag: vgp

tag: vgp type

value: Epithelioid and Spindled

tag: precursor

tag: mitotic rate

tag: tils

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Metastatic Melanoma_Sample 99.6

source_name: Metastatic Melanoma, Sample 99.6

tag: tissue type

value: Metastatic Melanoma

tag: patient id

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: left thigh

tag: location

value: cutaneous/subcutaneous

tag: organ

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[2,75]

value: Clark's level:[IV]

tag: corresponding primary tumor

value: Histologic Type:[NMM]

tag: prior ctx, rtx, itx

value: 1/97 INF-a s.c.; 2/98 hyperthermic limb perfusion (Melphalan); 3/99-11/99 chemotherapy Vindesine

tag: subsequent metastasis

value: 1/02 lungs, pleura (subsequent polychemotherapy Temodal, Vindesine, Carboplatin; complete remission)

tag: first instance [fi] or recurrance [r]

value: R

tag: other concurrent malignant tumors?

value: no

tag: past malignant tumors?

value: Jan 03, alive, NED


title: Primary Melanoma_Sample 103.4

source_name: Primary Melanoma, Sample 103.4

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: backside

value: caucasian

value: 8/01 LNN retrojugular, retroclavicular, retrosternal, pretracheal

value: FI

tag: last clinical status

value: Sep 03, alive, NED

tag: type

value: SSM, sec. nodular

tag: ulceration

tag: clark's

value: IV

tag: breslow thickness

tag: ulceration size

tag: rgp

value: Yes

tag: vgp

tag: vgp type

value: Epithelioid

tag: precursor

value: DN

tag: mitotic rate

tag: tils

value: Non-brisk

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites

tag: comments

value: metastatic disease at first diagnosis


title: Metastatic Melanoma_Sample 99.3

source_name: Metastatic Melanoma, Sample 99.3

tag: tissue type

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

tag: location

value: subcutaneous

tag: organ

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: 3 C new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[6,0]

value: Clark's level:[IV]

tag: corresponding primary tumor

value: Histologic Type:[NMM]

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: no further clinical data

tag: other concurrent malignant tumors?

tag: past malignant tumors?

tag: last clinical status


title: Primary Melanoma_Sample 103.2

source_name: Primary Melanoma, Sample 103.2

tag: tissue type

value: Primary Melanoma

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: left thigh

value: female

value: caucasian

value: 2 A new AJCC

value: no

tag: first instance [fi] or recurrance [r]

value: FI

value: Sep 03, alive, NED

tag: type

value: SSM

tag: ulceration

tag: clark's

tag: breslow thickness

tag: ulceration size

tag: rgp

tag: vgp

tag: vgp type

tag: precursor

value: No

tag: mitotic rate

tag: tils

value: Absent

tag: neural invasion

tag: vascular

tag: regression

tag: microsatellites


title: Metastatic Melanoma_Sample 92.3

source_name: Metastatic Melanoma, Sample 92.3

tag: tissue type

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: other cell types

value: Few Fibrous strands

tag: necrosis (% of total area)

tag: body-site

value: right cervical

tag: location

value: Lymph Node

tag: organ

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: 3 B new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[4,5]

value: Clark's level:[V]

tag: corresponding primary tumor

value: Histologic Type:[SSM, sec.nod]

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: 9/00 liver, lung, heart, spleen, cutis, LNN

tag: other concurrent malignant tumors?

tag: past malignant tumors?

tag: last clinical status

value: Dez 00, death, MM-related


title: Metastatic Melanoma_Sample 92.6

source_name: Metastatic Melanoma, Sample 92.6

tag: tissue type

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: other cell types

value: Skin

tag: necrosis (% of total area)

value: right lower leg

value: cutaneous

value: skin

value: female

value: caucasian

value: Breslow index, mm:[2,5]

value: Clark's level:[IV]

value: Histologic Type:[ALM]

value: 12/99 + 8/00 hyperthermic limb perfusion of right leg [Melphalan]; 7/00 CTX Temodal; from 5/01 12 cycles of DTIC, intralesional Proleukin-therapy:subcutaneous mets right leg

value: 9/01:cutaneous mets right leg, 5/02 cutaneous mets abdomen, mets lungs, mets intraabdominal

tag: first instance [fi] or recurrance [r]

value: R

value: no

value: Jun 02, death, MM-related


title: Metastatic Melanoma_Sample 91.1

source_name: Metastatic Melanoma, Sample 91.1

value: Metastatic Melanoma

tag: body-site

value: left thigh

tag: location

value: cutaneous/subcutaneous

tag: organ

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: 4 new AJCC

value: Breslow index, mm:[2,75]

value: Histologic Type:[NMM]

value: 1/97 INF-a s.c.; 2/98 hyperthermic limb perfusion (Melphalan); 3/99-11/99 chemotherapy Vindesine

value: 1/02 lungs, pleura (subsequent polychemotherapy Temodal, Vindesine, Carboplatin; complete remission)

value: FI

value: Jan 03, alive, NED


title: Nevus_Sample 100.5

source_name: Nevus, Sample 100.5

value: Nevus

tag: % melanocytes

tag: % keratinocytes

tag: diagnosis

value: melanocytic nevus, compound-type

tag: subtype

value: B, small epithelioid


title: Metastatic Melanoma_Sample 89.3

source_name: Metastatic Melanoma, Sample 89.3

tag: tissue type

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

value: right axilla

value: Lymph Node

value: caucasian

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[1,2]

value: Clark's level:[III]

tag: corresponding primary tumor

value: Histologic Type:NMM

tag: prior ctx, rtx, itx

value: since 4/00 polychemotherapy (DTIC + Vindesine + Carboplatin)

tag: subsequent metastasis

tag: other concurrent malignant tumors?

tag: past malignant tumors?

tag: last clinical status

value: Feb 03, alive, NED


title: Metastatic Melanoma_Sample 99.2

source_name: Metastatic Melanoma, Sample 99.2

value: Metastatic Melanoma

tag: % other cells

tag: other cell types

value: Epidermis

tag: necrosis (% of total area)

tag: body-site

value: right lower leg

tag: location

value: cutaneous

tag: organ

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: female

tag: race

tag: clinical stage

value: 3 C new AJCC

value: Breslow index, mm:[4,5]

value: Clark's level:[IV]

value: Histologic Type:[MM]

value: no

value: 8/00:Lnn, lungs

tag: first instance [fi] or recurrance [r]

value: Jan 01, alive with disease

tag: comments

value: 2 cell types in met


title: Metastatic Melanoma_Sample 91.2

source_name: Metastatic Melanoma, Sample 91.2

tag: tissue type

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

value: colon

value: colon/peritoneal

value: male

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[4,7]

tag: corresponding primary tumor

value: Histologic Type:[SSM, sec.nod.]

tag: prior ctx, rtx, itx

value: 1-6/94:6x immunochemotherapy (DTIC+IL2+INFa); 3/96 radiation therapy head; 11/96 radiation therapy spine; 8/94-3/95 8x polychemotherapy (DTIC + Vindesine + Carboplatin)

tag: subsequent metastasis

value: 1/98 progression liver and bone, 4/99 lung

value: FI

value: Mai 99, death, MM-related


title: Metastatic Melanoma_Sample 69.6

source_name: Metastatic Melanoma, Sample 69.6

value: Metastatic Melanoma

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: right thigh

tag: location

value: subcutaneous

tag: organ

value: skin

value: 3 C new AJCC

value: Breslow index, mm:[1,8]

value: Clark's level:[IV]

value: Histologic Type:[ALM]

value: 8/96 + 4/97 + 5/97:Lnn right inguinal; 7/97 brain

value: R

tag: other concurrent malignant tumors?

tag: past malignant tumors?

tag: last clinical status

value: 1998, death, MM-related

value: /extensive necrosis in adjacent areas


title: Metastatic Melanoma_Sample 88.5

source_name: Metastatic Melanoma, Sample 88.5

tag: tissue type

value: abdomen

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

value: caucasian

tag: clinical stage

value: 4 new AJCC

value: Breslow index, mm:[4,7]

value: Histologic Type:[SSM, sec.nod.]

tag: first instance [fi] or recurrance [r]

value: no


title: Metastatic Melanoma_Sample 92.5

source_name: Metastatic Melanoma, Sample 92.5

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: other cell types

value: Skin

value: left thigh

value: cutaneous

value: female

value: 3 B new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[7,5]

value: Clark's level:[V]

tag: corresponding primary tumor

value: Histologic Type:[SSM]

tag: prior ctx, rtx, itx

value: 8/97 cutis; 9/97 LN; 12/97 LN [recurrence]; 5/98 cutis; 7/98 LN [recurrence] + cutis; 7/98 liver, lung; 11/98 LN [recurrence]

value: FI

value: Feb 99, death, MM-related


title: Metastatic Melanoma_Sample 89.1

source_name: Metastatic Melanoma, Sample 89.1

tag: % other cells

tag: necrosis (% of total area)

tag: body-site

value: chest

tag: location

value: Lymph Node

tag: organ

value: male

value: caucasian

value: Breslow index, mm:[1,75]

value: Clark's level:[III]

tag: subsequent metastasis

value: 2/02:s.c. mets thoracal left, surgery

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Dez 02, alive, NED


title: Metastatic Melanoma_Sample 69.3

source_name: Metastatic Melanoma, Sample 69.3

tag: tissue type

value: Metastatic Melanoma

value: Skin

value: right lower leg

value: cutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

tag: clinical stage

value: 4 new AJCC

value: Breslow index, mm:[4]

value: Clark's level:[IV]

value: Histologic Type:[SSM, sec.nod.]

value: no

value: 6/92 liver, LN

tag: first instance [fi] or recurrance [r]

tag: last clinical status

value: Jul 92, death, MM-related


title: Metastatic Melanoma_Sample 69.2

source_name: Metastatic Melanoma, Sample 69.2

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

value: suprascapulär li B

value: Lymph Node

value: male

value: caucasian

value: 3 B new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[0,618]

tag: corresponding primary tumor

value: Histologic Type:[MM]

tag: prior ctx, rtx, itx

value: 12 x polychemotherapy (DTIC + Vindesine + Carboplatin)

value: 9/01 Lnn cervical right; 3/02 brain (single lesion) g-knife; 11/02 progression of brain met:chemotherapy Temodal

value: FI

value: Jan 03, alive, NED


title: Metastatic Melanoma_Sample 99.4

source_name: Metastatic Melanoma, Sample 99.4

value: Metastatic Melanoma

tag: % other cells

tag: other cell types

value: Skin

tag: necrosis (% of total area)

tag: body-site

value: right inguinal

tag: location

value: subcutaneous

tag: organ

value: skin

value: 4 new AJCC

value: Breslow index, mm:[>5]

value: Histologic Type:[SSM]

value: 1 cycle of immunochemotherapy (DTIC, Intron A), 7 cycles polychemotherapy (Temodal + Vindesine + Carboplatin)

tag: subsequent metastasis

value: 7/00 cutis, spleen; 9/01 cutis, liver.

tag: other concurrent malignant tumors?

value: Dez 01, death, MM-related

tag: comments

value: looks like lymphoma


title: Metastatic Melanoma_Sample 68.4

source_name: Metastatic Melanoma, Sample 68.4

tag: tissue type

value: Few Fibrous strands

value: left lower leg

value: cutaneous

tag: date of resection

tag: age at time of resection

tag: gender

value: female

tag: race

value: caucasian

tag: clinical stage

value: 3 C new AJCC

value: Breslow index, mm:[6,5]

value: Clark's level:[IV]

value: Histologic Type:[NMM]

value: no

tag: first instance [fi] or recurrance [r]

tag: past malignant tumors?

tag: last clinical status

value: Dez 95, death, MM-related


title: Metastatic Melanoma_Sample 69.1

source_name: Metastatic Melanoma, Sample 69.1

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

value: left inguinal

value: Lymph Node

value: male

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[0,7]

value: Clark's level:[III]

tag: corresponding primary tumor

tag: prior ctx, rtx, itx

value: no further clinical data

value: FI

value: 2000, death, MM-related


title: Metastatic Melanoma_Sample 68.6

source_name: Metastatic Melanoma, Sample 68.6

tag: tissue type

tag: other cell types

value: Skin

tag: necrosis (% of total area)

tag: body-site

value: left axilla

tag: location

value: subcutaneous

tag: organ

value: skin

value: 4 new AJCC

value: Breslow index, mm:[2,6]

value: Histologic Type:[SSM]

value: 4/93-7/93 3 x immunochemotherapy (DTIC + INF-a + IL-2); 6/94 embolisation of liver mets [Cisplatin]; 11/96-7/97 polychemotherapy (DTIC + Vindesine + Carboplatin); 8/97 radiation therapy brain [30 Gy]

tag: subsequent metastasis

value: 8/97 s.c. left scapula, right cheek, left upper leg; 8/97 brain

tag: other concurrent malignant tumors?

value: Nov 97, death, MM-related


title: Metastatic Melanoma_Sample 67.3

source_name: Metastatic Melanoma, Sample 67.3

value: Metastatic Melanoma

value: Epidermis/skin

value: facial

value: cutaneous

tag: date of resection

tag: age at time of resection

tag: gender

value: female

tag: race

value: caucasian

tag: clinical stage

value: Breslow index, mm:n.a.

value: Clark's level:n.a.

value: Histologic Type:[uvea]

value: no

tag: first instance [fi] or recurrance [r]

tag: past malignant tumors?

tag: last clinical status

value: Feb 99, death, MM-related


title: Metastatic Melanoma_Sample 67.6

source_name: Metastatic Melanoma, Sample 67.6

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

value: Few Fibrous strands

value: chest

value: subcutaneous

value: skin

value: male

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[8,0]

value: Clark's level:[IV]

tag: corresponding primary tumor

value: Histologic Type:[NMM]

tag: prior ctx, rtx, itx

value: FI

value: suspected rectal carcinoma

value: 1997, death, MM-unrelated


title: Metastatic Melanoma_Sample 69.5

source_name: Metastatic Melanoma, Sample 69.5

tag: tissue type

value: Metastatic Melanoma

tag: necrosis (% of total area)

tag: body-site

value: left axilla

tag: location

value: Lymph Node

tag: organ

value: caucasian

value: 3 B new AJCC

value: Breslow index, mm:[1,75]

value: Clark's level:[III]

value: Histologic Type:[SSM]

tag: subsequent metastasis

value: 9/00 left chest, 2/02:s.c. mets thoracal left

tag: other concurrent malignant tumors?

value: Dez 02, alive, NED


title: Metastatic Melanoma_Sample 66.6

source_name: Metastatic Melanoma, Sample 66.6

value: left lower leg

value: subcutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

tag: clinical stage

value: Breslow index, mm:[8]

value: 6/88 Interferon beta, 05/89 Interferon alpha, hyperthermic limb perfusion (Melphalan)

value: recurrent s.c. mets left leg

tag: first instance [fi] or recurrance [r]

value: no

tag: past malignant tumors?

value: Feb 03, alive, NED


title: Metastatic Melanoma_Sample 68.2

source_name: Metastatic Melanoma, Sample 68.2

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: other cell types

value: Skin

value: neck

value: female

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[1,4]

value: Clark's level:[V]

value: 1 cycle of immunochemotherapy (DTIC, Proleukin, Intron A)

value: 7/98:lungs, intraabdominal, s.c., brain

value: FI

tag: last clinical status

value: 2000, death, MM-related


title: Metastatic Melanoma_Sample 69.4

source_name: Metastatic Melanoma, Sample 69.4

tag: tissue type

tag: necrosis (% of total area)

tag: body-site

value: right axilla

tag: location

value: cutaneous

tag: organ

value: skin

value: male

value: caucasian

value: no further clinical data

value: Breslow index, mm:no further clinical data

value: Clark's level:no further clinical data

tag: corresponding primary tumor

value: Histologic Type:no further clinical data

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: Nov 99, death, MM-related


title: Metastatic Melanoma_Sample 67.5

source_name: Metastatic Melanoma, Sample 67.5

value: Metastatic Melanoma

value: chest

value: Lymph Node

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

tag: clinical stage

value: 3 B new AJCC

value: Breslow index, mm:[0,618]

value: Clark's level:[IV]

value: Histologic Type:[MM]

value: 12 x polychemotherapy (DTIC + Vindesine + Carboplatin)

value: 9/01 Lnn cervical right; 3/02 brain (single lesion) g-knife; 11/02 progression of brain met:chemotherapy Temodal

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: no

tag: past malignant tumors?

value: Jan 03, alive, NED


title: Metastatic Melanoma_Sample 67.4

source_name: Metastatic Melanoma, Sample 67.4

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

value: female

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[8]

value: Histologic Type:[NMM]

value: 11x immunochemotherapy (DTIC+IL2+INFa);  adjuvant immunotherapy INF-a

value: no (complete remission since 4/00)

value: FI

tag: last clinical status


title: Metastatic Melanoma_Sample 66.5

source_name: Metastatic Melanoma, Sample 66.5

tag: tissue type

value: Metastatic Melanoma

tag: necrosis (% of total area)

tag: location

value: mesenterial

tag: organ

value: male

value: Breslow index, mm:[4,7]

tag: corresponding primary tumor

value: Histologic Type:[SSM, sec.nod.]

tag: prior ctx, rtx, itx

value: 1-6/94:6x immunochemotherapy (DTIC+IL2+INFa); 3/96 radiation therapy head; 11/96 radiation therapy spine; 8/94-3/95 8x polychemotherapy (DTIC + Vindesine + Carboplatin)

value: 1/98 progression liver and bone, 4/99 lung

value: Mai 99, death, MM-related


title: Metastatic Melanoma_Sample 18.2

source_name: Metastatic Melanoma, Sample 18.2

tag: body-site

value: abdominal

value: subcutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

tag: clinical stage

value: Breslow index, mm:[0,75]

value: Clark's level:[IV]

value: Histologic Type:[SSM]

value: 3 cycles of immunochemotherapy (DTIC, Intron A, Proleukin)

tag: subsequent metastasis

value: R

value: no

value: 1996, death, MM-related


title: Metastatic Melanoma_Sample 105.5

source_name: Metastatic Melanoma, Sample 105.5

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: other cell types

value: Skin

value: backside

value: cutaneous/subcutaneous

value: caucasian

value: 4 new AJCC

value: Breslow index, mm:[5,0]

value: Clark's level:[V]

value: Histologic Type:[NMM]

value: 7/01 scull (bone); lungs, Lnn, cutis

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Okt 02, death, MM-related


title: Metastatic Melanoma_Sample 64.5

source_name: Metastatic Melanoma, Sample 64.5

tag: tissue type

tag: necrosis (% of total area)

value: right axilla

tag: location

value: subcutaneous

tag: organ

value: skin

value: female

value: 4 C new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[1,8]

value: Clark's level:[IV]

tag: corresponding primary tumor

value: Histologic Type:[SSM]

value: 8/99:lungs, intraabdominal, spleen, liver

tag: last clinical status

value: 1999, death, MM-related


title: Metastatic Melanoma_Sample 65.4

source_name: Metastatic Melanoma, Sample 65.4

value: Metastatic Melanoma

tag: body-site

value: abdomen

tag: date of resection

tag: age at time of resection

tag: gender

value: male

tag: race

value: caucasian

tag: clinical stage

value: 4 new AJCC

value: Breslow index, mm:[2,6]

tag: prior ctx, rtx, itx

value: 4/93-7/93 3 x immunochemotherapy (DTIC + INF-a + IL-2); 6/94 embolisation of liver mets [Cisplatin]; 11/96-7/97 polychemotherapy (DTIC + Vindesine + Carboplatin); 8/97 radiation therapy brain [30 Gy]

tag: subsequent metastasis

value: 8/97 s.c. left scapula, right cheek, left upper leg; 8/97 brain

value: no

value: Nov 97, death, MM-related


title: Metastatic Melanoma_Sample 18.4

source_name: Metastatic Melanoma, Sample 18.4

tag: patient id

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

tag: other cell types

value: Skin

value: right lower leg

value: subcutaneous

value: skin

value: 3 B new AJCC

value: Breslow index, mm:[4]

value: Histologic Type:[ALM]

value: 5/95 local recurrance, 9/95 LNN,

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Apr 97, death, MM-related

tag: comments

value: 2 cell types in met (spindle/epitheloid)


title: Metastatic Melanoma_Sample 64.3

source_name: Metastatic Melanoma, Sample 64.3

tag: tissue type

value: Metastatic Melanoma

tag: necrosis (% of total area)

tag: body-site

value: right inguinal

tag: location

tag: organ

value: male

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[>3,0]

value: Clark's level:[II]

tag: corresponding primary tumor

value: Histologic Type:[NMM]

value: 10/95-1/96 3 x polychemotherapy (DTIC + Vindesine + Carboplatin)

value: 7/97:Lnn right inguinal, right kidney, left suprarenal gland; 3/98:brain, lung, liver, kidney, cutis

tag: last clinical status

value: Feb 99, death, MM-related


title: Metastatic Melanoma_Sample 66.2

source_name: Metastatic Melanoma, Sample 66.2

tag: patient id

tag: % melanoma cells

value: chest

value: subcutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

tag: clinical stage

value: Breslow index, mm:[0,4]

value: Histologic Type:[SSM]

tag: prior ctx, rtx, itx

value: no

tag: subsequent metastasis

value: 8/97 brain, progression of pulmonal mets, progression of LNN mets axillar and mediastinal, suspected adrenal mets, suspected liver mets, progression of cutaneous mets

value: Okt 97, death, MM-related


title: Metastatic Melanoma_Sample 66.1

source_name: Metastatic Melanoma, Sample 66.1

tag: tissue type

value: Metastatic Melanoma

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: male

value: Breslow index, mm:[>25,0]

value: Clark's level:[V]

value: 3 cycles of polychemotherapy (DVP-regimen)

value: progression of known mets (s.c., lungs, liver, peritoneum, mediastinum)

tag: first instance [fi] or recurrance [r]

value: FI

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Aug 99, death, MM-related


title: Metastatic Melanoma_Sample 64.2

source_name: Metastatic Melanoma, Sample 64.2

tag: body-site

value: neck

tag: location

value: cutaneous

tag: organ

value: female

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[1,4]

tag: corresponding primary tumor

value: 1 cycle of immunochemotherapy (DTIC, Proleukin, Intron A)

value: 7/98:lungs, intraabdominal, s.c., brain

tag: last clinical status

value: 2000, death, MM-related


title: Metastatic Melanoma_Sample 105.4

source_name: Metastatic Melanoma, Sample 105.4

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

value: left lower leg

value: cutaneous/subcutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

tag: race

tag: clinical stage

value: Breslow index, mm:[4,4]

value: Clark's level:[IV]

value: no

value: 2/02 lung, soft tissue, GI

value: Feb 01, death, MM-related


title: Metastatic Melanoma_Sample 64.4

source_name: Metastatic Melanoma, Sample 64.4

tag: tissue type

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: right inguinal

value: Lymph Node

value: 3 C new AJCC

value: Breslow index, mm:[3,1]

value: Histologic Type:[NMM]

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: no further clinical data

tag: first instance [fi] or recurrance [r]

value: FI

value: Jun 99, alive with disease


title: Metastatic Melanoma_Sample 65.2

source_name: Metastatic Melanoma, Sample 65.2

value: Metastatic Melanoma

tag: body-site

value: left inguinal

tag: location

tag: organ

value: male

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[1,5]

value: Histologic Type:[SSM]

value: 1 cycle of polychemotherapy (DTIC, Cisplatin, Vindesine)

value: progression of mets:lung, liver, spleen, brain, LNN

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Sep 97, death, MM-related


title: Metastatic Melanoma_Sample 105.6

source_name: Metastatic Melanoma, Sample 105.6

tag: patient id

tag: % melanoma cells

tag: other cell types

value: Skin

value: chest

value: cutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: Breslow index, mm:[0,75]

value: Clark's level:[IV]

tag: corresponding primary tumor

value: from 8/99 4 cycles of polychemotherapy (Vindesine + Cisplatin), radiation therapy (Lnn left axilla) 12/99

value: no

tag: last clinical status

value: 2000, death, MM-related


title: Metastatic Melanoma_Sample 64.1

source_name: Metastatic Melanoma, Sample 64.1

tag: tissue type

value: Metastatic Melanoma

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: facial

value: male

tag: race

tag: clinical stage

value: Breslow index, mm:[3,5]

value: Histologic Type:[NMM]

tag: prior ctx, rtx, itx

value: 10 cycles of polychemotherapy (DTIC + Vindesine + Carboplatin), 3 cycles of polychemotherapy (Taxol+Tamoxifen+Cisplatin), radiation therapy brain (30 Gy)

tag: subsequent metastasis

value: progression of known mets

value: FI

value: Dez 99, death, MM-related


title: Metastatic Melanoma_Sample 15.3

source_name: Metastatic Melanoma, Sample 15.3

value: Skin

tag: body-site

value: abdomen

tag: location

value: subcutaneous

tag: organ

value: female

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[>5]

value: no further clinical data

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

tag: past malignant tumors?


title: Metastatic Melanoma_Sample 65.3

source_name: Metastatic Melanoma, Sample 65.3

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

value: right lower leg

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: Breslow index, mm:[>3,0]

value: Clark's level:[II]

tag: corresponding primary tumor

value: no

value: 9/95 lung; 10/95 LNN right inguinal; 8/96 LNN right axilla; 3/97 LNN right inguinal; 7/97:Lnn right inguinal, right kidney, left suprarenal gland; 3/98 brain, lung, liver, kidney, cutis

tag: last clinical status

value: Feb 99, death, MM-related


title: Metastatic Melanoma_Sample 66.4

source_name: Metastatic Melanoma, Sample 66.4

tag: tissue type

tag: % inflammatory cells

tag: % other cells

tag: other cell types

value: Few Fibrous strands

tag: necrosis (% of total area)

value: chest

value: male

tag: race

tag: clinical stage

value: Breslow index, mm:[0,4]

value: Histologic Type:[SSM]

tag: prior ctx, rtx, itx

value: 8/97 brain, progression of pulmonal mets, progression of LNN mets axillar and mediastinal, suspected adrenal mets, suspected liver mets, progression of cutaneous mets

value: FI

value: Okt 97, death, MM-related


title: Metastatic Melanoma_Sample 105.3

source_name: Metastatic Melanoma, Sample 105.3

value: Skin

tag: body-site

value: backside

tag: location

value: cutaneous

tag: organ

value: caucasian

value: 4 new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[4,4]

value: Clark's level:[IV]

value: 1 cycle of polychemotherapy (Temodal + Vindesine + Carboplatin) 12/00

tag: subsequent metastasis

value: 2/02 lung, soft tissue, GI

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: Feb 01, death, MM-related


title: Metastatic Melanoma_Sample 105.2

source_name: Metastatic Melanoma, Sample 105.2

value: Metastatic Melanoma

tag: patient id

tag: % melanoma cells

value: right lower leg

value: cutaneous/subcutaneous

value: skin

tag: date of resection

tag: age at time of resection

tag: gender

value: female

value: Breslow index, mm:[?]

value: Clark's level:[III]

value: 2-9/99 3x3 Mio IE Interferon/week + 7 cycles chemotherapy DTIC.

value: 9/99 brain, LNN

value: no

tag: past malignant tumors?

tag: last clinical status

value: 2000, death, MM-related


title: Metastatic Melanoma_Sample 104.3

source_name: Metastatic Melanoma, Sample 104.3

tag: tissue type

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: left thigh

value: male

tag: race

value: caucasian

tag: clinical stage

value: 4 new AJCC

value: Breslow index, mm:[>5]

tag: corresponding primary tumor

value: Histologic Type:[SSM]

value: 7/00 cutis, spleen; 9/01 cutis, liver.

value: FI

value: Dez 01, death, MM-related


title: Metastatic Melanoma_Sample MM.I

description: Met.MM.I

source_name: Metastatic Melanoma, Sample MM.I

value: Metastatic Melanoma


title: Metastatic Melanoma_Sample MM.L

description: Met.MM.L

source_name: Metastatic Melanoma, Sample MM.L


title: Metastatic Melanoma_Sample 105.1

source_name: Metastatic Melanoma, Sample 105.1

tag: other cell types

value: Skin

tag: body-site

value: chest

tag: location

value: cutaneous

tag: organ

value: skin

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[2,3]

value: Histologic Type:[NMM]

tag: prior ctx, rtx, itx

value: 2 cycles polychemotherapy (DTIC, Cisplatin, Vindesine)

tag: subsequent metastasis

value: 5/99 brain, meningeosis carcinomatosa; 6/99 cutis.

value: Sep 99, death, MM-related


title: Metastatic Melanoma_Sample 104.2

source_name: Metastatic Melanoma, Sample 104.2

tag: patient id

tag: % melanoma cells

value: abdomen

tag: date of resection

tag: age at time of resection

tag: gender

value: male

value: caucasian

value: Clark's level:[IV]

value: 1 cycle of immunochemotherapy (DTIC, Intron A)

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

value: no

tag: past malignant tumors?


title: Metastatic Melanoma_Sample 102.2

source_name: Metastatic Melanoma, Sample 102.2

tag: tissue type

tag: % inflammatory cells

tag: % other cells

tag: necrosis (% of total area)

value: left knee

tag: race

tag: clinical stage

value: 4 new AJCC

value: Breslow index, mm:[2,75]

tag: corresponding primary tumor

value: 1/97 INF-a s.c.; 2/98 hyperthermic limb perfusion (Melphalan); 3/99-11/99 chemotherapy Vindesine

value: 1/02 lungs, pleura (subsequent polychemotherapy Temodal, Vindesine, Carboplatin; complete remission)

value: FI

tag: last clinical status

value: Jan 03, alive, NED

tag: comments

value: tumor cell number, is this an inflammatory infiltrate?


title: Metastatic Melanoma_Sample 101.6

source_name: Metastatic Melanoma, Sample 101.6

value: Metastatic Melanoma

tag: patient id

tag: other cell types

value: Muscle

tag: body-site

value: right lower leg

tag: location

value: cutaneous

tag: organ

value: skin

value: female

value: 3 C new AJCC

tag: tnm status

tag: corresponding primary tumor thickness

value: Breslow index, mm:[4,5]

value: Histologic Type:[MM]

tag: prior ctx, rtx, itx

tag: subsequent metastasis

value: 8/00:Lnn, lungs

value: Jan 01, alive with disease


title: Metastatic Melanoma_Sample MM.H

description: Met.MM.H

source_name: Metastatic Melanoma, Sample MM.H

tag: tissue type


title: Metastatic Melanoma_Sample MM.K

description: Met.MM.K

source_name: Metastatic Melanoma, Sample MM.K


title: Metastatic Melanoma_Sample 104.4

source_name: Metastatic Melanoma, Sample 104.4

tag: % melanoma cells

tag: % inflammatory cells

tag: % other cells

value: left axilla

tag: date of resection

tag: age at time of resection

tag: gender

value: male

value: caucasian

value: 4 new AJCC

value: Breslow index, mm:[0,4]

value: Clark's level:[II]

value: Histologic Type:[SSM]

value: no

value: 8/97 brain, progression of pulmonal mets, progression of LNN mets axillar and mediastinal, suspected adrenal mets, suspected liver mets, progression of cutaneous mets

tag: first instance [fi] or recurrance [r]

tag: other concurrent malignant tumors?

tag: past malignant tumors?

value: Okt 97, death, MM-related


title: Metastatic Melanoma_Sample MM.A

description: Met.MM.A

source_name: Metastatic Melanoma, Sample MM.A

value: Metastatic Melanoma


title: Metastatic Melanoma_Sample MM.E

description: Met.MM.E

source_name: Metastatic Melanoma, Sample MM.E


title: Metastatic Melanoma_Sample MM.B

description: Met.MM.B

source_name: Metastatic Melanoma, Sample MM.B


title: Metastatic Melanoma_Sample C018

source_name: Metastatic Melanoma, Sample C018


title: Metastatic Melanoma_Sample C038

source_name: Metastatic Melanoma, Sample C038


title: Metastatic Melanoma_Sample MM.F

description: Met.MM.F

source_name: Metastatic Melanoma, Sample MM.F


title: Metastatic Melanoma_Sample C025

source_name: Metastatic Melanoma, Sample C025


title: Metastatic Melanoma_Sample C012

source_name: Metastatic Melanoma, Sample C012


title: Metastatic Melanoma_Sample C007

source_name: Metastatic Melanoma, Sample C007


title: Metastatic Melanoma_Sample C014

source_name: Metastatic Melanoma, Sample C014


title: Metastatic Melanoma_Sample C009

source_name: Metastatic Melanoma, Sample C009


title: Metastatic Melanoma_Sample C027

source_name: Metastatic Melanoma, Sample C027


title: Metastatic Melanoma_Sample C022

source_name: Metastatic Melanoma, Sample C022


title: Metastatic Melanoma_Sample C010

source_name: Metastatic Melanoma, Sample C010


title: Metastatic Melanoma_Sample C024

source_name: Metastatic Melanoma, Sample C024


title: Metastatic Melanoma_Sample C015

source_name: Metastatic Melanoma, Sample C015


title: Metastatic Melanoma_Sample C021

source_name: Metastatic Melanoma, Sample C021