title: ∆rad52_+ARS317_Sector sample 6

value: G0 (stationary phase)

value: 3 hours

value: Mitosis (nocodazole arrest)


title: MCF7-Dicer inhibition-3

status: Public on Jul 25 2014

type: RNA

city: Bedford Park

first: Kanchana

middle: Veronika

last: Bandara

state: SA

address: Flinders Drive

department: Renal Department

country: Australia

institute: Flinders University

description:
mammary gland/breast; derived from metastatic site: pleural effusion
Mature miRNA and precursor miRNA expression data

hyb_protocol: Following biotinylation, these fragments were hybridised overnight to a Affymetrix miRNA 3.1 array

scan_protocol: The arrays were then washed, stained using a fluorescently-labelled antibody, and scanned using a high-resolution scanner (GeneChip® Scanner 3000 7G). Affymetrix® GeneChi  p® Command Console® (AGCC) Software

data_processing: Intensity data were analysed using Partek® software (Partek Inc.). Data were normalised by quantile normalisation and log 2 transformed. Differential expression was determined by ANOVA and corrected for false discovery.

label: biotin

molecule: total RNA

organism: Homo sapiens

source_name: MCF7-Dicer siRNA

label_protocol: 100-300 ng of total RNA was used to synthesise double stranded cDNA using random hexamers. The cDNA was then amplified to produce antisense cRNA, which was then reverse transcribed in a second cycle of cDNA synthesis. The second cycle incorporates dUTP into the cDNA sequence, which allows it to be fragmented using uracil DNA glycosylase and apurinic/apyrimidic endonuclease I.

growth_protocol: Breast cancer cell line MCF7 was maintained in RPMI 1640 (Invitrogen) medium supplemented with 10% foetal bovine serum (FBS) (Bovigen), in polystyrene flasks. Cells were maintained at 37 ºC with 5% CO2. All experiments were conducted in triplicate with independent cell cultures.

extract_protocol: Total RNA was extracted using TRIzol reagent (Invitrogen) following the manufacturers protocol. RNA quantity and quality were determined using a Nanodrop-8000 spectrophotometer (Nanodrop Technology) and Agilent 2100 Bioanalyzer.

treatment_protocol: A hypoxic incubator (Coy Laboratory Hypoxic workstation glove box) was used to expose cells to continuous controlled hypoxic conditions. This humidified, temperature controlled (37 ºC) chamber supplemented with 5% CO2, and N2 (as required to maintain controlled O2 levels). Cells were exposed to 0.1% O2 levels for 48 h. Normoxic controls were incubated in parallel in a humidified incubator supplemented with 5% CO2 at 37 ºC. MCF7 cells were seeded at 50 000 cells per well in 24-well plates (1.9 cm2) and grown for 24 h. Cells were transfected with 20 nM siRNA duplexes (Shanghai GenePharma Co., Ltd, China), using Lipofectamine 2000 reagent (Invitrogen) following the manufacturer’s protocol. A second transfection was carried out after 24 h following the same protocol. Cells were harvested 24 h after the second transfection and used for RNA and protein extraction.

tag: cell line

tag: treatment

value: Dicer inhibition


title: ∆rad52_+ARS317_Sector sample 1

type: genomic

city: San Francisco

first: Stacey

middle: L

last: Hanlon

state: California

address: 600 16th Street Genentech Hall S376

department: Biochemistry and Biophysics

country: USA

institute: University of California, San Francisco

description: Used for chromosome copy number analysis in Hanlon and Li, 2014

hyb_protocol: Hybridization was performed in 3X SSC + 25mM HEPES pH7.0 + 0.25% SDS at 63C for 18-48 hours.

scan_protocol: Arrays were scanned with an Axon 3000B scanner using GenePixPro6.0.

data_processing: Data were filtered in GenePix to flag as bad features that had : (1) obvious defects; (2) saturated pixels; (3) regression r^2 values less than 0.5; (4) fewer than 55% of their pixels with flourescence intensity greater than 2 standard deviations above background. BLAST analysis was used to generate a filter that would flag as bad elements whose PCR product were excessively repetitive. Raw Cy3/Cy5 median of ratios values were normalized such that the average ratio was equal to 1. VALUE is the log2 of the normalized ratio of Cy3 to Cy5; note that to convert to usable copy number profiles raise two to the indicated value.

molecule: genomic DNA

organism: Saccharomyces cerevisiae

source_name: Red sector of a red/pink sectored colony

label_protocol: Amino-allyl-dUTP incorporation with Klenow. Chemical coupling of dye to aa-dUTP labelled DNA.

extract_protocol: Small DNA prep

tag: strain parent

tag: position in cell cycle prepratory to dna extraction

tag: induction time

tag: colony number

tag: sector color

value: Red

source_name: Non-re-replicating strain arrested in mitosis

extract_protocol: Clean Genomic Prep

tag: strain


title: MCF7-Dicer inhibition-2


title: ∆rad52_+ARS317_Sector sample 2

source_name: Pink sector of a red/pink sectored colony

value: Pink


title: Sample 83_Liver, 100 µg/kg, 3 hour

city: Research Triangle Park

first: Nigel

last: Walker

state: NC

address: 111 T.W. Alexander Drive

institute: National Institute of Environmental Health Sciences

hyb_protocol: Labeled cRNA was fragmented and hybridized to the Affymetrix Rat Genome 230 2.0 Array. Array hybridization was performed using an Affymetrix GeneChip Hybridization Oven 640. Washing, and staining of the arrays were completed using the Affymetrix GeneChip Hybridization Wash and Stain kit and performed according to the Affymetrix recommended protocol FS450 _ 0001.

scan_protocol: After washing, the arrays were scanned using an Affymetrix GeneChip Scanner 3000 7G and the acquired data was then further analyzed by the Affymetrix GeneChip Operating Software (GCOS) version 1.4.

data_processing: Normalized expression of probe level data was calculated using the Robust Multiarray Average function (RMA) implemented in Bioconductor's affy-package.

label: Biotin

organism: Rattus norvegicus

source_name: Liver, 100 µg/kg, 3 hour

label_protocol: The cDNA served as a template to synthesize biotin-labeled antisense cRNA using an in vitro transcription (lVT) Labeling Kit.

extract_protocol: Tissue samples were excised from the left lobe of the liver from male Wistar Han rats, which received an intravenous dosage of sterile PBS (Control) or microcystin-LR at concentrations of 1, 10, 50 or 100 microg/kg. These tissues were collected after 0.5, 1,3, or 6 hr exposures for each dosage group and transferred on ice to the Battelle Biomedical Research Center (BBRC) from Battelle Columbus Operations (BCO) in 50-mL conical tubes filled with RNAlater (Ambion, Inc., Austin, TX), one sample per tube. Upon arrival the tissue samples were inventoried and stored at 2-8degreesC for a period of time no longer than seven days until processed for RNA isolation. Between 130 mg and 150 mg of each liver tissue sample was removed from the RNAlater added to lysis buffer and homogenized for 45 seconds using OmniTip plastic disposable probes (Omni International, Marietta, GA). Following homogenization, samples were stored at  70C until processed for RNA isolation. Immediately before processing, the homogenates were thawed at 37DC, centrifuged and RNA was extracted from the supernatant  using the Qiagen RNeasy Midi Kit (Qiagen, Valencia, CA). Each RNA sample was analyzed for quantity and purity by UV analysis using the NanoDrop ND 1000 Spectrophotometer (NanoDrop Technologies, Wilmington, DE). All samples were evaluated for RNA integrity by gel electrophoresis using the FlashGel RNA cassette system (Lonza, Rockland, ME).

tag: tissue

value: Liver

tag: compound

value: Microcystin-LR

tag: dose

value: 100 µg/kg

tag: time

value: 3 hour

tag: vehicle

value: PBS

tag: route

value: IV

tag: Sex

value: Male

tag: age

value: 12 - 14 weeks


title: Sample 90_Liver, 100 µg/kg, 6 hour

source_name: Liver, 100 µg/kg, 6 hour

value: 6 hour


title: Sample 86_Liver, 100 µg/kg, 6 hour


title: Sample 89_Liver, 100 µg/kg, 6 hour


title: ∆rad52_+ARS317_Sector sample 5


title: Sample 79_Liver, 100 µg/kg, 0.5 hour

source_name: Liver, 100 µg/kg, 0.5 hour

value: 0.5 hour


title: WT_+ARS317_Sector sample 44


title: Sample 82_Liver, 100 µg/kg, 3 hour


title: Sample 88_Liver, 100 µg/kg, 6 hour


title: Sample 84_Liver, 100 µg/kg, 3 hour


title: Sample 80_Liver, 100 µg/kg, 0.5 hour


title: Sample 78_Liver, 100 µg/kg, 0.5 hour


title: ∆rad52_+ARS317_Sector sample 3


title: Sample 85_Liver, 100 µg/kg, 6 hour


title: Sample 87_Liver, 100 µg/kg, 6 hour


title: ∆rad52_+ARS317_Sector sample 4


title: MCF7-Dicer inhibition-1


title: WT_+ARS317_Sector sample 43


title: Sample 77_Liver, 100 µg/kg, 0.5 hour


title: Sample 81_Liver, 100 µg/kg, 3 hour


title: WT_+ARS317_Sector sample 41


title: WT_+ARS317_Sector sample 42


title: Sample 73_Liver, 100 µg/kg, 1 hour

source_name: Liver, 100 µg/kg, 1 hour

value: 1 hour


title: WT_+ARS317_Sector sample 40

value: G0 (stationary phase)


title: Sample 69_Liver, 50 µg/kg, 6 hour

source_name: Liver, 50 µg/kg, 6 hour

value: 50 µg/kg


title: Sample 71_Liver, 50 µg/kg, 6 hour


title: Sample 75_Liver, 100 µg/kg, 1 hour


title: Sample 67_Liver, 50 µg/kg, 6 hour


title: Sample 76_Liver, 100 µg/kg, 1 hour


title: Sample 72_Liver, 50 µg/kg, 6 hour


title: Sample 65_Liver, 50 µg/kg, 3 hour

source_name: Liver, 50 µg/kg, 3 hour


title: Sample 74_Liver, 100 µg/kg, 1 hour


title: WT_+ARS317_Sector sample 38

value: 3 hours

value: Mitosis (nocodazole arrest)


title: Sample 61_Liver, 50 µg/kg, 0.5 hour

source_name: Liver, 50 µg/kg, 0.5 hour


title: WT_+ARS317_Sector sample 39

value: Red


title: Sample 66_Liver, 50 µg/kg, 3 hour


title: WT_+ARS317_Sector sample 36

value: Pink


title: WT_+ARS317_Sector sample 37


title: Sample 70_Liver, 50 µg/kg, 6 hour

value: Liver


title: Sample 62_Liver, 50 µg/kg, 0.5 hour

value: Microcystin-LR


title: WT_+ARS317_Sector sample 35


title: Sample 63_Liver, 50 µg/kg, 3 hour


title: Sample 64_Liver, 50 µg/kg, 3 hour


title: Sample 68_Liver, 50 µg/kg, 6 hour


title: WT_+ARS317_Sector sample 34


title: Sample 58_Liver, 50 µg/kg, 1 hour

source_name: Liver, 50 µg/kg, 1 hour


title: WT_+ARS317_Sector sample 33


title: WT_+ARS317_Sector sample 31


title: Sample 60_Liver, 50 µg/kg, 0.5 hour


title: WT_+ARS317_Sector sample 32


title: Sample 54_Liver, 10 µg/kg, 6 hour

source_name: Liver, 10 µg/kg, 6 hour

value: 10 µg/kg


title: WT_+ARS317_Sector sample 30


title: Sample 52_Liver, 10 µg/kg, 6 hour


title: Sample 57_Liver, 50 µg/kg, 1 hour


title: WT_+ARS317_Sector sample 28


title: Sample 56_Liver, 50 µg/kg, 1 hour


title: Sample 53_Liver, 10 µg/kg, 6 hour


title: WT_+ARS317_Sector sample 27


title: Sample 50_Liver, 10 µg/kg, 6 hour


title: WT_+ARS317_Sector sample 26


title: Sample 46_Liver, 10 µg/kg, 3 hour

source_name: Liver, 10 µg/kg, 3 hour

value: 3 hour


title: Sample 45_Liver, 10 µg/kg, 3 hour

value: PBS


title: Sample 44_Liver, 10 µg/kg, 0.5 hour

source_name: Liver, 10 µg/kg, 0.5 hour

value: IV


title: Sample 48_Liver, 10 µg/kg, 3 hour

value: Male


title: Sample 59_Liver, 50 µg/kg, 0.5 hour

value: 12 - 14 weeks


title: Sample 49_Liver, 10 µg/kg, 6 hour

value: 6 hour


title: Sample 42_Liver, 10 µg/kg, 0.5 hour

value: 0.5 hour


title: WT_+ARS317_Sector sample 29


title: Sample 40_Liver, 10 µg/kg, 1 hour

source_name: Liver, 10 µg/kg, 1 hour

value: 1 hour


title: Sample 47_Liver, 10 µg/kg, 3 hour


title: Sample 51_Liver, 10 µg/kg, 6 hour


title: Sample 55_Liver, 50 µg/kg, 1 hour


title: WT_+ARS317_Sector sample 24

value: G0 (stationary phase)


title: WT_+ARS317_Sector sample 25


title: Sample 38_Liver, 10 µg/kg, 1 hour


title: WT_+ARS317_Sector sample 23


title: Sample 41_Liver, 10 µg/kg, 0.5 hour


title: Sample 43_Liver, 10 µg/kg, 0.5 hour


title: Sample 39_Liver, 10 µg/kg, 1 hour


title: Sample 34_Liver, 1 µg/kg, 6 hour

source_name: Liver, 1 µg/kg, 6 hour

value: 1 µg/kg


title: Sample 37_Liver, 10 µg/kg, 1 hour


title: WT_–ARS317_Sector sample 28

value: 3 hours


title: Sample 33_Liver, 1 µg/kg, 6 hour


title: Sample 36_Liver, 1 µg/kg, 6 hour


title: Sample 30_Liver, 1 µg/kg, 3 hour

source_name: Liver, 1 µg/kg, 3 hour


title: Sample 32_Liver, 1 µg/kg, 6 hour


title: Sample 31_Liver, 1 µg/kg, 6 hour


title: WT_–ARS317_Sector sample 27

source_name: Red sector of a red/pink sectored colony

value: Mitosis (nocodazole arrest)


title: WT_–ARS317_Sector sample 23

value: Red

source_name: Non-re-replicating strain arrested in mitosis


title: WT_–ARS317_Sector sample 25


title: Sample 25_Liver, 1 µg/kg, 0.5 hour

source_name: Liver, 1 µg/kg, 0.5 hour


title: Sample 29_Liver, 1 µg/kg, 3 hour


title: WT_–ARS317_Sector sample 24

source_name: Pink sector of a red/pink sectored colony

value: Pink


title: Sample 28_Liver, 1 µg/kg, 3 hour

value: Liver


title: Sample 27_Liver, 1 µg/kg, 3 hour

value: Microcystin-LR


title: Sample 26_Liver, 1 µg/kg, 0.5 hour


title: Sample 24_Liver, 1 µg/kg, 0.5 hour


title: WT_–ARS317_Sector sample 21


title: WT_–ARS317_Sector sample 26


title: Sample 35_Liver, 1 µg/kg, 6 hour


title: Sample 22_Liver, 1 µg/kg, 1 hour

source_name: Liver, 1 µg/kg, 1 hour


title: Sample 20_Liver, 1 µg/kg, 1 hour


title: Sample 23_Liver, 1 µg/kg, 0.5 hour


title: WT_–ARS317_Sector sample 19


title: WT_–ARS317_Sector sample 18


title: Sample 18_Liver, 0 µg/kg, 6 hour

source_name: Liver, 0 µg/kg, 6 hour

value: 0 µg/kg


title: Sample 19_Liver, 1 µg/kg, 1 hour


title: Sample 15_Liver, 0 µg/kg, 6 hour


title: WT_–ARS317_Sector sample 17


title: Sample 11_Liver, 0 µg/kg, 3 hour

source_name: Liver, 0 µg/kg, 3 hour

value: 3 hour


title: WT_–ARS317_Sector sample 20


title: WT_–ARS317_Sector sample 22


title: Sample 13_Liver, 0 µg/kg, 6 hour

value: PBS


title: Sample 12_Liver, 0 µg/kg, 3 hour

value: IV


title: WT_–ARS317_Sector sample 16


title: WT_–ARS317_Sector sample 15


title: Sample 16_Liver, 0 µg/kg, 6 hour

value: Male


title: Sample 10_Liver, 0 µg/kg, 3 hour

value: 12 - 14 weeks


title: Sample 9_Liver, 0 µg/kg, 3 hour


title: WT_–ARS317_Sector sample 13


title: Sample 17_Liver, 0 µg/kg, 6 hour

value: 6 hour


title: WT_–ARS317_Sector sample 14


title: Sample 6_Liver, 0 µg/kg, 0.5 hour

source_name: Liver, 0 µg/kg, 0.5 hour

value: 0.5 hour


title: Sample 21_Liver, 1 µg/kg, 1 hour

value: 1 hour


title: Sample 5_Liver, 0 µg/kg, 0.5 hour


title: Sample 7_Liver, 0 µg/kg, 0.5 hour


title: Sample 8_Liver, 0 µg/kg, 0.5 hour


title: Sample 4_Liver, 0 µg/kg, 1 hour

source_name: Liver, 0 µg/kg, 1 hour


title: Sample 2_Liver, 0 µg/kg, 1 hour


title: Sample 1_Liver, 0 µg/kg, 1 hour


title: Sample 3_Liver, 0 µg/kg, 1 hour


title: WT_–ARS317_Sector sample 11

value: G0 (stationary phase)


title: WT_–ARS317_Sector sample 10


title: WT_–ARS317_Sector sample 9


title: Sample 14_Liver, 0 µg/kg, 6 hour


title: WT_+ARS317_Sector sample 13

source_name: Red sector of a red/white sectored colony


title: WT_+ARS317_Sector sample 11


title: WT_+ARS317_Sector sample 17


title: WT_+ARS317_Sector sample 12

source_name: White sector of a red/white sectored colony

value: White


title: WT_+ARS317_Sector sample 14

value: 3 hours


title: WT_+ARS317_Sector sample 10

value: Mitosis (nocodazole arrest)


title: WT_–ARS317_Sector sample 12


title: WT_+ARS317_Sector sample 15

value: Red


title: WT_+ARS317_Sector sample 8


title: WT_+ARS317_Sector sample 18


title: WT_+ARS317_Sector sample 20


title: WT_+ARS317_Sector sample 19


title: WT_+ARS317_Sector sample 3


title: WT_+ARS317_Sector sample 5


title: WT_+ARS317_Sector sample 7


title: WT_+ARS317_Sector sample 6


title: WT_+ARS317_Sector sample 2


title: WT_–ARS317_Sector sample 7


title: WT_–ARS317_Sector sample 8


title: WT_+ARS317_Sector sample 16


title: WT_+ARS317_Sector sample 4


title: WT_–ARS317_Sector sample 4


title: WT_–ARS317_Sector sample 6


title: WT_+ARS317_Sector sample 1


title: ∆dnl4_+ARS317_3hr Re-rep

description: Used for re-replication analysis on Chromosome V in Hanlon and Li, 2014

source_name: Post-re-replication strain


title: WT_+ARS317_Sector sample 21


title: WT_+ARS317_3hr Re-rep_no arrest

value: Mitosis (endogenous arrest)


title: WT_–ARS317_Sector sample 2


title: ∆rad52∆dnl4_+ARS317_3hr Re-rep


title: WT_+ARS317 on ChrV arm_2hr Re-rep


title: WT_–ARS317_Sector sample 5


title: WT_+ARS317_3hr Re-rep


title: WT_–ARS317_3hr Re-rep_no arrest


title: WT_–ARS317_Sector sample 3


title: WT_–ARS317_Sector sample 1


title: WT_–ARS317_3hr Re-rep

value: 2 hours


title: ∆rad52_+ARS317_3hr Re-rep


title: WT_+ARS317_Sector sample 9


title: WT_+ARS317_Sector sample 22


title: OPGP Sample 402074RR

status: Public on Jul 24 2014

city: Toronto

first: Stephen

middle: W

last: Scherer

state: Ontario

address: 686 Bay Street

department: Genetics and Genomic Biology

country: Canada

institute: The Hospital for Sick Children

description: Sample name: 402074RR

hyb_protocol: DNA was hybridized to the array at 50C for 17 hours according to the manufacturer's instructions. The arrays were washed using Affymetrix Fluidics Stations.

scan_protocol: The arrays were scanned using the GeneChip Scanner 3000.

data_processing:
CYCHP files generated by Chromosome Analysis Suite (ChAS) version 1.15.0 (Affymetrix Linux apt program) are provided:
affymetrix-algorithm-name = CYTO2
affymetrix-algorithm-version = 1.15.0
program-name = apt-copynumber-cyto
program-version = 1.15.0
affymetrix-algorithm-param-option-reference-input = opgp953.REF_MODEL
To achieve comprehensive CNV calling, we used four separate algorithms to detect CNVs: Affymetrix Chromosome Analysis Suite (ChAS), iPattern, Nexus and Partek. Our primary analysis was performed based on ChAS CNV calls, which were then supported using the remaining three algorithms to construct a confidence set of CNVs14. For all algorithms, we have used 8 probes and >1kb as a base line cutoff for CNV detection.

source_name: lymphoblastoid cell line

label_protocol: DNA was restriction digested, PCR amplified, fragmented, and labeled as per the manufacturer (Affymetrix).

growth_protocol: Cell lines were grown according to standard conditions.

extract_protocol: Lymphocyte isolation by the Ficoll separation procedure followed by cryopreservation and storage in liquid nitrogen. Cell lines were established using EBV-transformation.

tag: cell type

value: lymphoblastoid cell line

tag: gender

value: female

tag: ethnicity

value: European


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description: Sample name: 402062KR


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description: Sample name: 402051AF


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description: Sample name: 402064DC

value: male


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description: Sample name: 400002HK


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description: Sample name: 402016HZ


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description: Sample name: 402024BB


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description: Sample name: 402073LQ

value: Asian


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description: Sample name: 402063WM


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description: Sample name: 402042BJ

value: Admixed


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title: OPGP Sample 401841OB

description: Sample name: 401841OB


title: OPGP Sample 401844ZD

description: Sample name: 401844ZD


title: OPGP Sample 401852SK

description: Sample name: 401852SK


title: OPGP Sample 401860TJ

description: Sample name: 401860TJ


title: OPGP Sample 401859GS

description: Sample name: 401859GS


title: OPGP Sample 401856GC

description: Sample name: 401856GC


title: OPGP Sample 401857VG

description: Sample name: 401857VG


title: OPGP Sample 401838EN

description: Sample name: 401838EN


title: OPGP Sample 401836SI

description: Sample name: 401836SI


title: OPGP Sample 401842BJ

description: Sample name: 401842BJ


title: OPGP Sample 401834CB

description: Sample name: 401834CB


title: OPGP Sample 401832MC

description: Sample name: 401832MC


title: OPGP Sample 401824MM

description: Sample name: 401824MM


title: OPGP Sample 401831TW

description: Sample name: 401831TW


title: OPGP Sample 401825TH

description: Sample name: 401825TH


title: OPGP Sample 401829FJ

description: Sample name: 401829FJ


title: OPGP Sample 401822TL

description: Sample name: 401822TL


title: OPGP Sample 401820SD

description: Sample name: 401820SD


title: OPGP Sample 401818PC

description: Sample name: 401818PC


title: OPGP Sample 401819BS

description: Sample name: 401819BS


title: OPGP Sample 401809FU

description: Sample name: 401809FU


title: OPGP Sample 401813DN

description: Sample name: 401813DN


title: OPGP Sample 401817MC

description: Sample name: 401817MC


title: OPGP Sample 401806DL

description: Sample name: 401806DL


title: OPGP Sample 401804FG

description: Sample name: 401804FG


title: OPGP Sample 401801LA

description: Sample name: 401801LA


title: OPGP Sample 401812HG

description: Sample name: 401812HG


title: OPGP Sample 401780BB

description: Sample name: 401780BB


title: OPGP Sample 401792KR

description: Sample name: 401792KR


title: OPGP Sample 401783BD

description: Sample name: 401783BD


title: OPGP Sample 401795SP

description: Sample name: 401795SP


title: OPGP Sample 401791FG

description: Sample name: 401791FG


title: OPGP Sample 401764JJ

description: Sample name: 401764JJ


title: OPGP Sample 401749DJ

description: Sample name: 401749DJ


title: OPGP Sample 401797LS

description: Sample name: 401797LS


title: OPGP Sample 401778CB

description: Sample name: 401778CB


title: OPGP Sample 401785MJ

description: Sample name: 401785MJ


title: OPGP Sample 401786WD

description: Sample name: 401786WD


title: OPGP Sample 401799DP

description: Sample name: 401799DP


title: OPGP Sample 401766MR

description: Sample name: 401766MR


title: OPGP Sample 401762SD

description: Sample name: 401762SD


title: OPGP Sample 401771OS

description: Sample name: 401771OS


title: OPGP Sample 401773AM

description: Sample name: 401773AM


title: OPGP Sample 401734PG

description: Sample name: 401734PG


title: OPGP Sample 401808PS

description: Sample name: 401808PS


title: OPGP Sample 401739BJ

description: Sample name: 401739BJ


title: OPGP Sample 401736BF

description: Sample name: 401736BF


title: OPGP Sample 401746WW

description: Sample name: 401746WW


title: OPGP Sample 401735LE

description: Sample name: 401735LE


title: OPGP Sample 401733CG

description: Sample name: 401733CG


title: OPGP Sample 401781SL

description: Sample name: 401781SL


title: OPGP Sample 401763SG

description: Sample name: 401763SG


title: OPGP Sample 401729AC

description: Sample name: 401729AC


title: OPGP Sample 401769CR

description: Sample name: 401769CR


title: OPGP Sample 401732HW

description: Sample name: 401732HW


title: OPGP Sample 401730MS

description: Sample name: 401730MS


title: OPGP Sample 401742KB

description: Sample name: 401742KB


title: OPGP Sample 401714BM

description: Sample name: 401714BM


title: OPGP Sample 401725MR

description: Sample name: 401725MR


title: OPGP Sample 401728WK

description: Sample name: 401728WK


title: OPGP Sample 401726LW

description: Sample name: 401726LW


title: OPGP Sample 401719RL

description: Sample name: 401719RL


title: OPGP Sample 401711WS

description: Sample name: 401711WS


title: OPGP Sample 401698SB

description: Sample name: 401698SB


title: OPGP Sample 401717LP

description: Sample name: 401717LP


title: OPGP Sample 401721CP

description: Sample name: 401721CP


title: OPGP Sample 401693RC

description: Sample name: 401693RC


title: OPGP Sample 401695BT

description: Sample name: 401695BT


title: OPGP Sample 401700BN_1

description: Sample name: 401700BN_1


title: OPGP Sample 401702GB

description: Sample name: 401702GB


title: OPGP Sample 401696CG

description: Sample name: 401696CG


title: OPGP Sample 401687LR

description: Sample name: 401687LR


title: OPGP Sample 401691HA

description: Sample name: 401691HA


title: OPGP Sample 401677MM

description: Sample name: 401677MM


title: OPGP Sample 401706BJ

description: Sample name: 401706BJ


title: OPGP Sample 401694SG

description: Sample name: 401694SG


title: OPGP Sample 401674DD

description: Sample name: 401674DD


title: OPGP Sample 401681MS

description: Sample name: 401681MS


title: OPGP Sample 401661HD

description: Sample name: 401661HD


title: OPGP Sample 401664SD

description: Sample name: 401664SD


title: OPGP Sample 401673DM

description: Sample name: 401673DM


title: OPGP Sample 401672FD

description: Sample name: 401672FD


title: OPGP Sample 401690HA

description: Sample name: 401690HA


title: OPGP Sample 401655DC

description: Sample name: 401655DC


title: OPGP Sample 401640WJ

description: Sample name: 401640WJ


title: OPGP Sample 401634CH

description: Sample name: 401634CH


title: OPGP Sample 401630MK

description: Sample name: 401630MK


title: OPGP Sample 401646MC

description: Sample name: 401646MC


title: OPGP Sample 401636WR

description: Sample name: 401636WR


title: OPGP Sample 401623SN

description: Sample name: 401623SN


title: OPGP Sample 401619BT

description: Sample name: 401619BT


title: OPGP Sample 401618HR

description: Sample name: 401618HR


title: OPGP Sample 401611CD

description: Sample name: 401611CD


title: OPGP Sample 401652HL

description: Sample name: 401652HL


title: OPGP Sample 401609MB

description: Sample name: 401609MB


title: OPGP Sample 401606CG

description: Sample name: 401606CG


title: OPGP Sample 401603HH

description: Sample name: 401603HH


title: OPGP Sample 401608GE

description: Sample name: 401608GE


title: OPGP Sample 401617KM

description: Sample name: 401617KM


title: OPGP Sample 401607LL

description: Sample name: 401607LL


title: OPGP Sample 401620BA

description: Sample name: 401620BA


title: OPGP Sample 401602PR

description: Sample name: 401602PR


title: OPGP Sample 401596PJ

description: Sample name: 401596PJ


title: OPGP Sample 401612HB

description: Sample name: 401612HB


title: OPGP Sample 401595BL

description: Sample name: 401595BL


title: OPGP Sample 401592NR

description: Sample name: 401592NR


title: OPGP Sample 401616WP

description: Sample name: 401616WP


title: OPGP Sample 401587RC

description: Sample name: 401587RC


title: OPGP Sample 401586RS

description: Sample name: 401586RS


title: OPGP Sample 401594MP

description: Sample name: 401594MP


title: OPGP Sample 401628GC

description: Sample name: 401628GC


title: OPGP Sample 401589HP

description: Sample name: 401589HP


title: OPGP Sample 401580CA

description: Sample name: 401580CA


title: OPGP Sample 401591BE

description: Sample name: 401591BE


title: OPGP Sample 401567BD

description: Sample name: 401567BD


title: OPGP Sample 401556KR

description: Sample name: 401556KR


title: OPGP Sample 401563TK

description: Sample name: 401563TK


title: OPGP Sample 401571SD

description: Sample name: 401571SD


title: OPGP Sample 401582GG

description: Sample name: 401582GG


title: OPGP Sample 401552BK

description: Sample name: 401552BK


title: OPGP Sample 401566DD

description: Sample name: 401566DD


title: OPGP Sample 401538NS

description: Sample name: 401538NS


title: OPGP Sample 401554VN

description: Sample name: 401554VN


title: OPGP Sample 401540GM

description: Sample name: 401540GM


title: OPGP Sample 401518VK

description: Sample name: 401518VK


title: OPGP Sample 401551MB

description: Sample name: 401551MB


title: OPGP Sample 401576WC

description: Sample name: 401576WC


title: OPGP Sample 401535RJ

description: Sample name: 401535RJ


title: OPGP Sample 401519SA

description: Sample name: 401519SA


title: OPGP Sample 401517PR

description: Sample name: 401517PR


title: OPGP Sample 401514BA

description: Sample name: 401514BA


title: OPGP Sample 401513KC

description: Sample name: 401513KC


title: OPGP Sample 401506LK

description: Sample name: 401506LK


title: OPGP Sample 401504RJ

description: Sample name: 401504RJ


title: OPGP Sample 401505WI

description: Sample name: 401505WI


title: OPGP Sample 401510DG

description: Sample name: 401510DG


title: OPGP Sample 401494PD

description: Sample name: 401494PD


title: OPGP Sample 401500OM

description: Sample name: 401500OM


title: OPGP Sample 401495NR

description: Sample name: 401495NR


title: OPGP Sample 401493HC

description: Sample name: 401493HC


title: OPGP Sample 401503MJ

description: Sample name: 401503MJ


title: OPGP Sample 401491BB

description: Sample name: 401491BB


title: OPGP Sample 401496SL

description: Sample name: 401496SL


title: OPGP Sample 401497PR

description: Sample name: 401497PR


title: OPGP Sample 401498HH

description: Sample name: 401498HH


title: OPGP Sample 401487FW

description: Sample name: 401487FW


title: OPGP Sample 401490TL

description: Sample name: 401490TL


title: OPGP Sample 401478RD

description: Sample name: 401478RD


title: OPGP Sample 401489CB

description: Sample name: 401489CB


title: OPGP Sample 401526WB

description: Sample name: 401526WB


title: OPGP Sample 401536BD

description: Sample name: 401536BD


title: OPGP Sample 401468RL

description: Sample name: 401468RL


title: OPGP Sample 401482CB

description: Sample name: 401482CB


title: OPGP Sample 401480PG

description: Sample name: 401480PG


title: OPGP Sample 401477ST

description: Sample name: 401477ST


title: OPGP Sample 401474CE

description: Sample name: 401474CE


title: OPGP Sample 401475MK

description: Sample name: 401475MK


title: OPGP Sample 401532LJ

description: Sample name: 401532LJ


title: OPGP Sample 401543DC

description: Sample name: 401543DC


title: OPGP Sample 401550SP

description: Sample name: 401550SP


title: OPGP Sample 401465TB

description: Sample name: 401465TB


title: OPGP Sample 401457WK

description: Sample name: 401457WK


title: OPGP Sample 401460LW

description: Sample name: 401460LW


title: OPGP Sample 401454CD

description: Sample name: 401454CD


title: OPGP Sample 401448BJ

description: Sample name: 401448BJ


title: OPGP Sample 401453OL

description: Sample name: 401453OL


title: OPGP Sample 401499JR

description: Sample name: 401499JR


title: OPGP Sample 401437MJ

description: Sample name: 401437MJ


title: OPGP Sample 401442WR

description: Sample name: 401442WR


title: OPGP Sample 401434VN

description: Sample name: 401434VN


title: OPGP Sample 401458RT

description: Sample name: 401458RT


title: OPGP Sample 401444LD

description: Sample name: 401444LD


title: OPGP Sample 401459HF

description: Sample name: 401459HF


title: OPGP Sample 401432SB

description: Sample name: 401432SB


title: OPGP Sample 401419SW

description: Sample name: 401419SW


title: OPGP Sample 401438HT

description: Sample name: 401438HT


title: OPGP Sample 401443JK

description: Sample name: 401443JK


title: OPGP Sample 401423BA

description: Sample name: 401423BA


title: OPGP Sample 401428LD

description: Sample name: 401428LD


title: OPGP Sample 401426WD

description: Sample name: 401426WD


title: OPGP Sample 401414CR

description: Sample name: 401414CR


title: OPGP Sample 401413RG

description: Sample name: 401413RG


title: OPGP Sample 401427CB

description: Sample name: 401427CB


title: OPGP Sample 401410BJ

description: Sample name: 401410BJ


title: OPGP Sample 401420PJ

description: Sample name: 401420PJ


title: OPGP Sample 401402EN

description: Sample name: 401402EN


title: OPGP Sample 401403TD

description: Sample name: 401403TD


title: OPGP Sample 401401BA

description: Sample name: 401401BA


title: OPGP Sample 401406KF

description: Sample name: 401406KF


title: OPGP Sample 401400NP

description: Sample name: 401400NP


title: OPGP Sample 401415CB

description: Sample name: 401415CB


title: OPGP Sample 401395OP

description: Sample name: 401395OP


title: OPGP Sample 401397WN

description: Sample name: 401397WN


title: OPGP Sample 401393JW

description: Sample name: 401393JW


title: OPGP Sample 401391PJ

description: Sample name: 401391PJ


title: OPGP Sample 401377MA

description: Sample name: 401377MA


title: OPGP Sample 401376RD

description: Sample name: 401376RD


title: OPGP Sample 401372RR

description: Sample name: 401372RR


title: OPGP Sample 401369GR

description: Sample name: 401369GR


title: OPGP Sample 401385BB

description: Sample name: 401385BB


title: OPGP Sample 401386WA

description: Sample name: 401386WA


title: OPGP Sample 401390DG

description: Sample name: 401390DG


title: OPGP Sample 401384BP

description: Sample name: 401384BP


title: OPGP Sample 401365DJ

description: Sample name: 401365DJ


title: OPGP Sample 401380OL

description: Sample name: 401380OL


title: OPGP Sample 401366WD

description: Sample name: 401366WD


title: OPGP Sample 401368WR

description: Sample name: 401368WR


title: OPGP Sample 401358VP

description: Sample name: 401358VP


title: OPGP Sample 401364GM

description: Sample name: 401364GM


title: OPGP Sample 401359HF

description: Sample name: 401359HF


title: OPGP Sample 401355CD

description: Sample name: 401355CD


title: OPGP Sample 401362ME

description: Sample name: 401362ME


title: OPGP Sample 401361GG

description: Sample name: 401361GG


title: OPGP Sample 401357MH

description: Sample name: 401357MH


title: OPGP Sample 401347DH

description: Sample name: 401347DH


title: OPGP Sample 401334DH

description: Sample name: 401334DH


title: OPGP Sample 401348RB

description: Sample name: 401348RB


title: OPGP Sample 401353BC

description: Sample name: 401353BC


title: OPGP Sample 401346FJ

description: Sample name: 401346FJ


title: OPGP Sample 401341TS

description: Sample name: 401341TS


title: OPGP Sample 401331LJ

description: Sample name: 401331LJ


title: OPGP Sample 401321CE

description: Sample name: 401321CE


title: OPGP Sample 401326LI

description: Sample name: 401326LI


title: OPGP Sample 401311GL

description: Sample name: 401311GL


title: OPGP Sample 401330RR

description: Sample name: 401330RR


title: OPGP Sample 401302LJ

description: Sample name: 401302LJ


title: OPGP Sample 401333MM

description: Sample name: 401333MM


title: OPGP Sample 401308LD

description: Sample name: 401308LD


title: OPGP Sample 401318AV

description: Sample name: 401318AV


title: OPGP Sample 401314MK

description: Sample name: 401314MK


title: OPGP Sample 401315HK

description: Sample name: 401315HK


title: OPGP Sample 401287CF

description: Sample name: 401287CF


title: OPGP Sample 401297KC

description: Sample name: 401297KC


title: OPGP Sample 401307VR

description: Sample name: 401307VR

value: African


title: OPGP Sample 401303FM

description: Sample name: 401303FM


title: OPGP Sample 401299ST

description: Sample name: 401299ST


title: OPGP Sample 401288LD

description: Sample name: 401288LD


title: OPGP Sample 401275SJ

description: Sample name: 401275SJ


title: OPGP Sample 401274PA

description: Sample name: 401274PA


title: OPGP Sample 401281BP

description: Sample name: 401281BP


title: OPGP Sample 401295HB

description: Sample name: 401295HB


title: OPGP Sample 401292ER

description: Sample name: 401292ER


title: OPGP Sample 401354KM

description: Sample name: 401354KM


title: OPGP Sample 401278DM

description: Sample name: 401278DM


title: OPGP Sample 401277RA

description: Sample name: 401277RA


title: OPGP Sample 401268PS

description: Sample name: 401268PS


title: OPGP Sample 401266HM

description: Sample name: 401266HM


title: OPGP Sample 401265CB

description: Sample name: 401265CB


title: OPGP Sample 401285HN

description: Sample name: 401285HN


title: OPGP Sample 401284GM

description: Sample name: 401284GM


title: OPGP Sample 401261HD

description: Sample name: 401261HD


title: OPGP Sample 401262RR

description: Sample name: 401262RR


title: OPGP Sample 401253MC

description: Sample name: 401253MC


title: OPGP Sample 401246HH

description: Sample name: 401246HH


title: OPGP Sample 401251WN

description: Sample name: 401251WN


title: OPGP Sample 401263HS

description: Sample name: 401263HS


title: OPGP Sample 401250WD

description: Sample name: 401250WD


title: OPGP Sample 401252AE

description: Sample name: 401252AE


title: OPGP Sample 401234MB

description: Sample name: 401234MB


title: OPGP Sample 401238QR

description: Sample name: 401238QR


title: OPGP Sample 401240ML

description: Sample name: 401240ML


title: OPGP Sample 401258PC

description: Sample name: 401258PC


title: OPGP Sample 401210PB

description: Sample name: 401210PB


title: OPGP Sample 401235IA

description: Sample name: 401235IA


title: OPGP Sample 401249TP

description: Sample name: 401249TP


title: OPGP Sample 401212HJ

description: Sample name: 401212HJ


title: OPGP Sample 401215MJ

description: Sample name: 401215MJ


title: OPGP Sample 401207DA

description: Sample name: 401207DA


title: OPGP Sample 401203MP

description: Sample name: 401203MP


title: OPGP Sample 401214BJ

description: Sample name: 401214BJ


title: OPGP Sample 401230NL

description: Sample name: 401230NL


title: OPGP Sample 401254AE

description: Sample name: 401254AE


title: OPGP Sample 401200BD

description: Sample name: 401200BD


title: OPGP Sample 401198TI

description: Sample name: 401198TI


title: OPGP Sample 401196CR

description: Sample name: 401196CR


title: OPGP Sample 401195PN

description: Sample name: 401195PN


title: OPGP Sample 401192MJ

description: Sample name: 401192MJ


title: OPGP Sample 401259LS

description: Sample name: 401259LS


title: OPGP Sample 401221LD

description: Sample name: 401221LD


title: OPGP Sample 401191MI

description: Sample name: 401191MI


title: OPGP Sample 401184MM

description: Sample name: 401184MM


title: OPGP Sample 401185LE

description: Sample name: 401185LE


title: OPGP Sample 401182OC

description: Sample name: 401182OC


title: OPGP Sample 401176BD

description: Sample name: 401176BD


title: OPGP Sample 401183HP

description: Sample name: 401183HP


title: OPGP Sample 401180GR

description: Sample name: 401180GR


title: OPGP Sample 401173AI

description: Sample name: 401173AI


title: OPGP Sample 401165SB

description: Sample name: 401165SB


title: OPGP Sample 401166WJ

description: Sample name: 401166WJ


title: OPGP Sample 401152MV

description: Sample name: 401152MV


title: OPGP Sample 401175FA

description: Sample name: 401175FA


title: OPGP Sample 401239PR

description: Sample name: 401239PR


title: OPGP Sample 401162TM

description: Sample name: 401162TM


title: OPGP Sample 401153HS

description: Sample name: 401153HS


title: OPGP Sample 401151RJ

description: Sample name: 401151RJ


title: OPGP Sample 401155ML

description: Sample name: 401155ML


title: OPGP Sample 401154BR

description: Sample name: 401154BR


title: OPGP Sample 401146US

description: Sample name: 401146US


title: OPGP Sample 401143LK

description: Sample name: 401143LK


title: OPGP Sample 401135CS

description: Sample name: 401135CS


title: OPGP Sample 401149VA

description: Sample name: 401149VA


title: OPGP Sample 401190WC

description: Sample name: 401190WC


title: OPGP Sample 401119DK

description: Sample name: 401119DK


title: OPGP Sample 401136LB

description: Sample name: 401136LB


title: OPGP Sample 401132CH

description: Sample name: 401132CH


title: OPGP Sample 401133JG

description: Sample name: 401133JG


title: OPGP Sample 401125LM

description: Sample name: 401125LM


title: OPGP Sample 401117GM

description: Sample name: 401117GM


title: OPGP Sample 401113MJ

description: Sample name: 401113MJ


title: OPGP Sample 401110GJ

description: Sample name: 401110GJ


title: OPGP Sample 401177SL

description: Sample name: 401177SL


title: OPGP Sample 401091HS

description: Sample name: 401091HS


title: OPGP Sample 401105WS

description: Sample name: 401105WS


title: OPGP Sample 401104DM

description: Sample name: 401104DM


title: OPGP Sample 401085LA_1

description: Sample name: 401085LA_1


title: OPGP Sample 401087SF

description: Sample name: 401087SF


title: OPGP Sample 401086MD

description: Sample name: 401086MD


title: OPGP Sample 401084TD

description: Sample name: 401084TD


title: OPGP Sample 401084BD

description: Sample name: 401084BD


title: OPGP Sample 401100SJ

description: Sample name: 401100SJ


title: OPGP Sample 401102RD

description: Sample name: 401102RD


title: OPGP Sample 401093VL

description: Sample name: 401093VL


title: OPGP Sample 401074CM_1

description: Sample name: 401074CM_1


title: OPGP Sample 401066MM

description: Sample name: 401066MM


title: OPGP Sample 401075MN

description: Sample name: 401075MN


title: OPGP Sample 401064FR

description: Sample name: 401064FR


title: OPGP Sample 401096SL

description: Sample name: 401096SL


title: OPGP Sample 401067BD

description: Sample name: 401067BD


title: OPGP Sample 401079HJ

description: Sample name: 401079HJ


title: OPGP Sample 401054VM

description: Sample name: 401054VM


title: OPGP Sample 401057SS

description: Sample name: 401057SS


title: OPGP Sample 401111LH

description: Sample name: 401111LH


title: OPGP Sample 401053MF

description: Sample name: 401053MF


title: OPGP Sample 401052BM

description: Sample name: 401052BM


title: OPGP Sample 401068SD

description: Sample name: 401068SD


title: OPGP Sample 401112LG_1

description: Sample name: 401112LG_1


title: OPGP Sample 401077VC

description: Sample name: 401077VC


title: OPGP Sample 401050GS

description: Sample name: 401050GS


title: OPGP Sample 401056TJ

description: Sample name: 401056TJ


title: OPGP Sample 401033DJ

description: Sample name: 401033DJ


title: OPGP Sample 401027KW

description: Sample name: 401027KW


title: OPGP Sample 401040KM

description: Sample name: 401040KM


title: OPGP Sample 401039PA

description: Sample name: 401039PA


title: OPGP Sample 401025SM

description: Sample name: 401025SM


title: OPGP Sample 401038LN

description: Sample name: 401038LN


title: OPGP Sample 401036WS

description: Sample name: 401036WS


title: OPGP Sample 401020DJ

description: Sample name: 401020DJ


title: OPGP Sample 401029SD_1

description: Sample name: 401029SD_1


title: OPGP Sample 401026AM

description: Sample name: 401026AM


title: OPGP Sample 401016IT

description: Sample name: 401016IT


title: OPGP Sample 401022ML

description: Sample name: 401022ML


title: OPGP Sample 401030GI

description: Sample name: 401030GI


title: OPGP Sample 401011PJ

description: Sample name: 401011PJ


title: OPGP Sample 401021SC

description: Sample name: 401021SC


title: OPGP Sample 400999HR

description: Sample name: 400999HR


title: OPGP Sample 401017SC

description: Sample name: 401017SC


title: OPGP Sample 400996MC

description: Sample name: 400996MC


title: OPGP Sample 401019MP

description: Sample name: 401019MP


title: OPGP Sample 401010HT

description: Sample name: 401010HT


title: OPGP Sample 401013GJ

description: Sample name: 401013GJ


title: OPGP Sample 401012TP

description: Sample name: 401012TP


title: OPGP Sample 400984LD

description: Sample name: 400984LD


title: OPGP Sample 401006ES

description: Sample name: 401006ES


title: OPGP Sample 400987FB

description: Sample name: 400987FB


title: OPGP Sample 401005BL

description: Sample name: 401005BL


title: OPGP Sample 400994HJ

description: Sample name: 400994HJ


title: OPGP Sample 400978JG

description: Sample name: 400978JG


title: OPGP Sample 400982BS

description: Sample name: 400982BS


title: OPGP Sample 400955BE

description: Sample name: 400955BE


title: OPGP Sample 400977SC

description: Sample name: 400977SC


title: OPGP Sample 400953MR

description: Sample name: 400953MR


title: OPGP Sample 400971MK

description: Sample name: 400971MK


title: OPGP Sample 400956AM

description: Sample name: 400956AM


title: OPGP Sample 400967PK

description: Sample name: 400967PK


title: OPGP Sample 400970VE

description: Sample name: 400970VE


title: OPGP Sample 400983PV

description: Sample name: 400983PV


title: OPGP Sample 400927BD

description: Sample name: 400927BD


title: OPGP Sample 400934LA

description: Sample name: 400934LA


title: OPGP Sample 400923OA

description: Sample name: 400923OA


title: OPGP Sample 400942HR

description: Sample name: 400942HR


title: OPGP Sample 400995MS

description: Sample name: 400995MS


title: OPGP Sample 400943DV

description: Sample name: 400943DV


title: OPGP Sample 400930MK

description: Sample name: 400930MK


title: OPGP Sample 400926LJ

description: Sample name: 400926LJ


title: OPGP Sample 400937OR

description: Sample name: 400937OR


title: OPGP Sample 400949AM

description: Sample name: 400949AM


title: OPGP Sample 400929MM

description: Sample name: 400929MM


title: OPGP Sample 400917CG

description: Sample name: 400917CG


title: OPGP Sample 400948EV

description: Sample name: 400948EV


title: OPGP Sample 400960TN

description: Sample name: 400960TN


title: OPGP Sample 400920MK

description: Sample name: 400920MK


title: OPGP Sample 400914ER

description: Sample name: 400914ER


title: OPGP Sample 400908PJ

description: Sample name: 400908PJ


title: OPGP Sample 400911GA

description: Sample name: 400911GA


title: OPGP Sample 400906BR

description: Sample name: 400906BR


title: OPGP Sample 400899NK

description: Sample name: 400899NK


title: OPGP Sample 400897MD

description: Sample name: 400897MD


title: OPGP Sample 400893ZE

description: Sample name: 400893ZE


title: OPGP Sample 400886MP

description: Sample name: 400886MP


title: OPGP Sample 400974PS

description: Sample name: 400974PS


title: OPGP Sample 400890IT

description: Sample name: 400890IT


title: OPGP Sample 400880TM

description: Sample name: 400880TM


title: OPGP Sample 400871CM

description: Sample name: 400871CM


title: OPGP Sample 400879DS

description: Sample name: 400879DS


title: OPGP Sample 400882DD

description: Sample name: 400882DD


title: OPGP Sample 400852WJ

description: Sample name: 400852WJ


title: OPGP Sample 400866RR

description: Sample name: 400866RR


title: OPGP Sample 400881GS

description: Sample name: 400881GS


title: OPGP Sample 400863SS

description: Sample name: 400863SS


title: OPGP Sample 400888MS

description: Sample name: 400888MS


title: OPGP Sample 400869BK

description: Sample name: 400869BK


title: OPGP Sample 400859SC

description: Sample name: 400859SC


title: OPGP Sample 400870KC

description: Sample name: 400870KC


title: OPGP Sample 400876OG

description: Sample name: 400876OG


title: OPGP Sample 400854SG

description: Sample name: 400854SG


title: OPGP Sample 400837HN

description: Sample name: 400837HN


title: OPGP Sample 400855BD

description: Sample name: 400855BD


title: OPGP Sample 400849SH

description: Sample name: 400849SH


title: OPGP Sample 400846MC

description: Sample name: 400846MC


title: OPGP Sample 400843FL

description: Sample name: 400843FL


title: OPGP Sample 400835FD

description: Sample name: 400835FD


title: OPGP Sample 400845ML

description: Sample name: 400845ML


title: OPGP Sample 400844GP

description: Sample name: 400844GP


title: OPGP Sample 400834SS

description: Sample name: 400834SS


title: OPGP Sample 400836LK

description: Sample name: 400836LK


title: OPGP Sample 400889CM

description: Sample name: 400889CM


title: OPGP Sample 400825TW

description: Sample name: 400825TW


title: OPGP Sample 400829MR

description: Sample name: 400829MR


title: OPGP Sample 400818BL

description: Sample name: 400818BL


title: OPGP Sample 400833BB

description: Sample name: 400833BB


title: OPGP Sample 400817MB

description: Sample name: 400817MB


title: OPGP Sample 400802DP

description: Sample name: 400802DP


title: OPGP Sample 400811SK

description: Sample name: 400811SK


title: OPGP Sample 400827MM

description: Sample name: 400827MM


title: OPGP Sample 400821FE

description: Sample name: 400821FE


title: OPGP Sample 400791GC

description: Sample name: 400791GC


title: OPGP Sample 400797ST

description: Sample name: 400797ST


title: OPGP Sample 400789KV

description: Sample name: 400789KV


title: OPGP Sample 400838AM

description: Sample name: 400838AM


title: OPGP Sample 400800MW

description: Sample name: 400800MW


title: OPGP Sample 400795CL

description: Sample name: 400795CL


title: OPGP Sample 400801HS

description: Sample name: 400801HS


title: OPGP Sample 400769SL

description: Sample name: 400769SL


title: OPGP Sample 400782IE

description: Sample name: 400782IE


title: OPGP Sample 400793BR

description: Sample name: 400793BR


title: OPGP Sample 400792RE

description: Sample name: 400792RE


title: OPGP Sample 400773GS

description: Sample name: 400773GS


title: OPGP Sample 400778SR

description: Sample name: 400778SR


title: OPGP Sample 400783MJ

description: Sample name: 400783MJ


title: OPGP Sample 400768MN

description: Sample name: 400768MN


title: OPGP Sample 400763BT

description: Sample name: 400763BT


title: OPGP Sample 400759FV

description: Sample name: 400759FV


title: OPGP Sample 400770MA

description: Sample name: 400770MA


title: OPGP Sample 400785AK

description: Sample name: 400785AK


title: OPGP Sample 400743LS

description: Sample name: 400743LS


title: OPGP Sample 400739SS_1

description: Sample name: 400739SS_1


title: OPGP Sample 400758KP

description: Sample name: 400758KP


title: OPGP Sample 400738WM

description: Sample name: 400738WM


title: OPGP Sample 400733SW

description: Sample name: 400733SW


title: OPGP Sample 400732MA

description: Sample name: 400732MA


title: OPGP Sample 400724CD

description: Sample name: 400724CD


title: OPGP Sample 400737GC

description: Sample name: 400737GC


title: OPGP Sample 400721DJ

description: Sample name: 400721DJ


title: OPGP Sample 400729HC

description: Sample name: 400729HC


title: OPGP Sample 400730SH

description: Sample name: 400730SH


title: OPGP Sample 400728PB

description: Sample name: 400728PB


title: OPGP Sample 400749VW

description: Sample name: 400749VW


title: OPGP Sample 400717BD

description: Sample name: 400717BD


title: OPGP Sample 400718PS

description: Sample name: 400718PS


title: OPGP Sample 400722OM

description: Sample name: 400722OM


title: OPGP Sample 400712GC

description: Sample name: 400712GC


title: OPGP Sample 400705KK

description: Sample name: 400705KK


title: OPGP Sample 400704LC

description: Sample name: 400704LC


title: OPGP Sample 400702PA

description: Sample name: 400702PA


title: OPGP Sample 400695PH

description: Sample name: 400695PH


title: OPGP Sample 400788PV

description: Sample name: 400788PV


title: OPGP Sample 400683EC

description: Sample name: 400683EC


title: OPGP Sample 400701MM

description: Sample name: 400701MM


title: OPGP Sample 400688FL

description: Sample name: 400688FL


title: OPGP Sample 400681MC

description: Sample name: 400681MC


title: OPGP Sample 400719TM

description: Sample name: 400719TM


title: OPGP Sample 400675HC

description: Sample name: 400675HC


title: OPGP Sample 400674CA

description: Sample name: 400674CA


title: OPGP Sample 400686BM

description: Sample name: 400686BM


title: OPGP Sample 400669LD

description: Sample name: 400669LD


title: OPGP Sample 400677HD

description: Sample name: 400677HD


title: OPGP Sample 400671PP

description: Sample name: 400671PP


title: OPGP Sample 400668TD

description: Sample name: 400668TD


title: OPGP Sample 400663MD

description: Sample name: 400663MD


title: OPGP Sample 400653GP

description: Sample name: 400653GP


title: OPGP Sample 400660GK

description: Sample name: 400660GK


title: OPGP Sample 400658BW

description: Sample name: 400658BW


title: OPGP Sample 400655WB

description: Sample name: 400655WB


title: OPGP Sample 400649PS

description: Sample name: 400649PS


title: OPGP Sample 400661AD

description: Sample name: 400661AD


title: OPGP Sample 400650RM

description: Sample name: 400650RM


title: OPGP Sample 400654YW

description: Sample name: 400654YW


title: OPGP Sample 400645KM

description: Sample name: 400645KM


title: OPGP Sample 400634MP

description: Sample name: 400634MP


title: OPGP Sample 400643LD

description: Sample name: 400643LD


title: OPGP Sample 400639RP

description: Sample name: 400639RP


title: OPGP Sample 400624RJ

description: Sample name: 400624RJ


title: OPGP Sample 400629BM

description: Sample name: 400629BM


title: OPGP Sample 400631SJ

description: Sample name: 400631SJ


title: OPGP Sample 400627CC

description: Sample name: 400627CC


title: OPGP Sample 400625FT

description: Sample name: 400625FT


title: OPGP Sample 400618GC

description: Sample name: 400618GC


title: OPGP Sample 400626FC

description: Sample name: 400626FC


title: OPGP Sample 400619MP

description: Sample name: 400619MP


title: OPGP Sample 400615RI

description: Sample name: 400615RI


title: OPGP Sample 400609FJ

description: Sample name: 400609FJ


title: OPGP Sample 400611GG

description: Sample name: 400611GG


title: OPGP Sample 400641WJ

description: Sample name: 400641WJ


title: OPGP Sample 400620MT

description: Sample name: 400620MT


title: OPGP Sample 400603CJ

description: Sample name: 400603CJ


title: OPGP Sample 400600DP

description: Sample name: 400600DP


title: OPGP Sample 400598DA

description: Sample name: 400598DA


title: OPGP Sample 400601WC

description: Sample name: 400601WC


title: OPGP Sample 400606HW

description: Sample name: 400606HW


title: OPGP Sample 400586RD

description: Sample name: 400586RD


title: OPGP Sample 400622SJ

description: Sample name: 400622SJ


title: OPGP Sample 400595CP

description: Sample name: 400595CP


title: OPGP Sample 400588BE

description: Sample name: 400588BE


title: OPGP Sample 400594VJ

description: Sample name: 400594VJ


title: OPGP Sample 400582WS

description: Sample name: 400582WS


title: OPGP Sample 400583HS

description: Sample name: 400583HS


title: OPGP Sample 400599CP

description: Sample name: 400599CP


title: OPGP Sample 400581VJ

description: Sample name: 400581VJ


title: OPGP Sample 400577MK

description: Sample name: 400577MK


title: OPGP Sample 400574MA

description: Sample name: 400574MA


title: OPGP Sample 400579HJ

description: Sample name: 400579HJ


title: OPGP Sample 400572PJ

description: Sample name: 400572PJ


title: OPGP Sample 400570RW

description: Sample name: 400570RW


title: OPGP Sample 400571WV

description: Sample name: 400571WV


title: OPGP Sample 400569WC

description: Sample name: 400569WC


title: OPGP Sample 400564SN

description: Sample name: 400564SN


title: OPGP Sample 400547BS

description: Sample name: 400547BS


title: OPGP Sample 400542EG

description: Sample name: 400542EG


title: OPGP Sample 400543CK

description: Sample name: 400543CK


title: OPGP Sample 400554WB

description: Sample name: 400554WB


title: OPGP Sample 400545EW_1

description: Sample name: 400545EW_1


title: OPGP Sample 400540BM

description: Sample name: 400540BM


title: OPGP Sample 400534ME

description: Sample name: 400534ME


title: OPGP Sample 400558BL

description: Sample name: 400558BL


title: OPGP Sample 400526DR

description: Sample name: 400526DR


title: OPGP Sample 400528LR

description: Sample name: 400528LR


title: OPGP Sample 400525MR

description: Sample name: 400525MR


title: OPGP Sample 400533BB

description: Sample name: 400533BB


title: OPGP Sample 400523GB

description: Sample name: 400523GB


title: OPGP Sample 400512LR

description: Sample name: 400512LR


title: OPGP Sample 400532MH

description: Sample name: 400532MH


title: OPGP Sample 400553PP

description: Sample name: 400553PP


title: OPGP Sample 400520FM

description: Sample name: 400520FM


title: OPGP Sample 400515ZG

description: Sample name: 400515ZG


title: OPGP Sample 400518MS

description: Sample name: 400518MS


title: OPGP Sample 400509CJ

description: Sample name: 400509CJ


title: OPGP Sample 40050SB

description: Sample name: 40050SB


title: OPGP Sample 400507VD

description: Sample name: 400507VD


title: OPGP Sample 400508RD

description: Sample name: 400508RD


title: OPGP Sample 400524NJ

description: Sample name: 400524NJ


title: OPGP Sample 400502GS

description: Sample name: 400502GS


title: OPGP Sample 400503HD

description: Sample name: 400503HD


title: OPGP Sample 400506GN

description: Sample name: 400506GN


title: OPGP Sample 400501SJ

description: Sample name: 400501SJ


title: OPGP Sample 400486LS

description: Sample name: 400486LS


title: OPGP Sample 400494ML

description: Sample name: 400494ML


title: OPGP Sample 400478WE

description: Sample name: 400478WE


title: OPGP Sample 400483DP

description: Sample name: 400483DP


title: OPGP Sample 400493KH

description: Sample name: 400493KH


title: OPGP Sample 400455SJ

description: Sample name: 400455SJ


title: OPGP Sample 400454RE

description: Sample name: 400454RE


title: OPGP Sample 400471YS

description: Sample name: 400471YS


title: OPGP Sample 400496BL

description: Sample name: 400496BL


title: OPGP Sample 400482MD

description: Sample name: 400482MD


title: OPGP Sample 400468OB

description: Sample name: 400468OB


title: OPGP Sample 400449PK

description: Sample name: 400449PK


title: OPGP Sample 400460DM

description: Sample name: 400460DM


title: OPGP Sample 400450FG

description: Sample name: 400450FG


title: OPGP Sample 400442FE

description: Sample name: 400442FE


title: OPGP Sample 400458LS

description: Sample name: 400458LS


title: OPGP Sample 400451kh

description: Sample name: 400451kh


title: OPGP Sample 400453LN

description: Sample name: 400453LN


title: OPGP Sample 400441GS

description: Sample name: 400441GS


title: OPGP Sample 400439IM

description: Sample name: 400439IM


title: OPGP Sample 400444MM

description: Sample name: 400444MM


title: OPGP Sample 400474GF

description: Sample name: 400474GF


title: OPGP Sample 400429YF

description: Sample name: 400429YF


title: OPGP Sample 400438DB

description: Sample name: 400438DB


title: OPGP Sample 400427SD

description: Sample name: 400427SD


title: OPGP Sample 400425SL

description: Sample name: 400425SL


title: OPGP Sample 400432VA

description: Sample name: 400432VA


title: OPGP Sample 400430KV

description: Sample name: 400430KV


title: OPGP Sample 400416KA

description: Sample name: 400416KA


title: OPGP Sample 400413FJ

description: Sample name: 400413FJ


title: OPGP Sample 400387HE

description: Sample name: 400387HE


title: OPGP Sample 400411TG

description: Sample name: 400411TG


title: OPGP Sample 400378HL

description: Sample name: 400378HL


title: OPGP Sample 400379BB_1

description: Sample name: 400379BB_1


title: OPGP Sample 400381CA

description: Sample name: 400381CA


title: OPGP Sample 400410CD

description: Sample name: 400410CD


title: OPGP Sample 400422PN

description: Sample name: 400422PN


title: OPGP Sample 400383HL

description: Sample name: 400383HL


title: OPGP Sample 400374LB

description: Sample name: 400374LB


title: OPGP Sample 400376SJ

description: Sample name: 400376SJ


title: OPGP Sample 400364SS

description: Sample name: 400364SS


title: OPGP Sample 400377WJ

description: Sample name: 400377WJ


title: OPGP Sample 400371GA

description: Sample name: 400371GA


title: OPGP Sample 400360SM

description: Sample name: 400360SM


title: OPGP Sample 400368SD

description: Sample name: 400368SD


title: OPGP Sample 400375KA

description: Sample name: 400375KA


title: OPGP Sample 400424LN

description: Sample name: 400424LN


title: OPGP Sample 400362TV

description: Sample name: 400362TV


title: OPGP Sample 400354TJ

description: Sample name: 400354TJ


title: OPGP Sample 400352CA

description: Sample name: 400352CA


title: OPGP Sample 400353ML

description: Sample name: 400353ML


title: OPGP Sample 400359OR

description: Sample name: 400359OR


title: OPGP Sample 400348DK

description: Sample name: 400348DK


title: OPGP Sample 400361HC

description: Sample name: 400361HC


title: OPGP Sample 400347VJ

description: Sample name: 400347VJ


title: OPGP Sample 400356MC

description: Sample name: 400356MC


title: OPGP Sample 400344DR_1

description: Sample name: 400344DR_1


title: OPGP Sample 400341GL

description: Sample name: 400341GL


title: OPGP Sample 400340CD

description: Sample name: 400340CD


title: OPGP Sample 400343BD

description: Sample name: 400343BD


title: OPGP Sample 400338SR

description: Sample name: 400338SR


title: OPGP Sample 400385LJ

description: Sample name: 400385LJ


title: OPGP Sample 400336BG

description: Sample name: 400336BG


title: OPGP Sample 400329HJ

description: Sample name: 400329HJ


title: OPGP Sample 400320RN

description: Sample name: 400320RN


title: OPGP Sample 400337HG

description: Sample name: 400337HG


title: OPGP Sample 40031BA

description: Sample name: 40031BA


title: OPGP Sample 400328LM

description: Sample name: 400328LM


title: OPGP Sample 400323AA

description: Sample name: 400323AA


title: OPGP Sample 400319HT

description: Sample name: 400319HT


title: OPGP Sample 400333CC

description: Sample name: 400333CC


title: OPGP Sample 400302HW

description: Sample name: 400302HW


title: OPGP Sample 400308SP

description: Sample name: 400308SP


title: OPGP Sample 400316SL

description: Sample name: 400316SL


title: OPGP Sample 400315DA_1

description: Sample name: 400315DA_1


title: OPGP Sample 400294HD

description: Sample name: 400294HD


title: OPGP Sample 400307HW

description: Sample name: 400307HW


title: OPGP Sample 400325BE

description: Sample name: 400325BE


title: OPGP Sample 400313DF

description: Sample name: 400313DF


title: OPGP Sample 400291VJ

description: Sample name: 400291VJ


title: OPGP Sample 400300SD

description: Sample name: 400300SD


title: OPGP Sample 400287BP

description: Sample name: 400287BP


title: OPGP Sample 400277LM

description: Sample name: 400277LM


title: OPGP Sample 400285FA

description: Sample name: 400285FA


title: OPGP Sample 400278PD

description: Sample name: 400278PD


title: OPGP Sample 400292LP

description: Sample name: 400292LP


title: OPGP Sample 400272AE

description: Sample name: 400272AE


title: OPGP Sample 400266BA

description: Sample name: 400266BA


title: OPGP Sample 400271SR

description: Sample name: 400271SR


title: OPGP Sample 400274TL

description: Sample name: 400274TL


title: OPGP Sample 400298ME

description: Sample name: 400298ME


title: OPGP Sample 400270BD

description: Sample name: 400270BD


title: OPGP Sample 400265LK

description: Sample name: 400265LK


title: OPGP Sample 400261RN

description: Sample name: 400261RN


title: OPGP Sample 400268SY

description: Sample name: 400268SY


title: OPGP Sample 400295PS

description: Sample name: 400295PS


title: OPGP Sample 400269DA

description: Sample name: 400269DA


title: OPGP Sample 400248JO

description: Sample name: 400248JO


title: OPGP Sample 400282RA

description: Sample name: 400282RA


title: OPGP Sample 400245SJ

description: Sample name: 400245SJ


title: OPGP Sample 400247CL

description: Sample name: 400247CL


title: OPGP Sample 400312CR

description: Sample name: 400312CR


title: OPGP Sample 400242TP

description: Sample name: 400242TP


title: OPGP Sample 400241CP

description: Sample name: 400241CP


title: OPGP Sample 400267GD

description: Sample name: 400267GD


title: OPGP Sample 400249BC

description: Sample name: 400249BC


title: OPGP Sample 400236DB_1

description: Sample name: 400236DB_1


title: OPGP Sample 400235MP_1

description: Sample name: 400235MP_1


title: OPGP Sample 400231LP

description: Sample name: 400231LP


title: OPGP Sample 400230TB

description: Sample name: 400230TB


title: OPGP Sample 400258BC

description: Sample name: 400258BC


title: OPGP Sample 400227MM

description: Sample name: 400227MM


title: OPGP Sample 400243CK

description: Sample name: 400243CK


title: OPGP Sample 400218WK

description: Sample name: 400218WK


title: OPGP Sample 400225CJ

description: Sample name: 400225CJ


title: OPGP Sample 400206SC

description: Sample name: 400206SC


title: OPGP Sample 400213DB

description: Sample name: 400213DB


title: OPGP Sample 400246MG

description: Sample name: 400246MG


title: OPGP Sample 400221VM

description: Sample name: 400221VM


title: OPGP Sample 400255CD

description: Sample name: 400255CD


title: OPGP Sample 400209BS_1

description: Sample name: 400209BS_1


title: OPGP Sample 400211BJ

description: Sample name: 400211BJ


title: OPGP Sample 400238BB

description: Sample name: 400238BB


title: OPGP Sample 400207HN

description: Sample name: 400207HN


title: OPGP Sample 400205SP_1

description: Sample name: 400205SP_1


title: OPGP Sample 400204SC

description: Sample name: 400204SC


title: OPGP Sample 400240HJ

description: Sample name: 400240HJ


title: OPGP Sample 400201PK

description: Sample name: 400201PK


title: OPGP Sample 400203NA

description: Sample name: 400203NA


title: OPGP Sample 400234CA

description: Sample name: 400234CA


title: OPGP Sample 400178RH

description: Sample name: 400178RH


title: OPGP Sample 400198MD

description: Sample name: 400198MD


title: OPGP Sample 400186WC

description: Sample name: 400186WC


title: OPGP Sample 400168HC

description: Sample name: 400168HC


title: OPGP Sample 400177SJ

description: Sample name: 400177SJ


title: OPGP Sample 400171BJ

description: Sample name: 400171BJ


title: OPGP Sample 400191MP_1

description: Sample name: 400191MP_1


title: OPGP Sample 400156WT_1

description: Sample name: 400156WT_1


title: OPGP Sample 400164SS

description: Sample name: 400164SS


title: OPGP Sample 400158FB

description: Sample name: 400158FB


title: OPGP Sample 400155CW

description: Sample name: 400155CW


title: OPGP Sample 400150SS

description: Sample name: 400150SS


title: OPGP Sample 400199SA_1

description: Sample name: 400199SA_1


title: OPGP Sample 400138LA

description: Sample name: 400138LA


title: OPGP Sample 400141CC

description: Sample name: 400141CC


title: OPGP Sample 400134WK_1

description: Sample name: 400134WK_1


title: OPGP Sample 400135DR

description: Sample name: 400135DR


title: OPGP Sample 400136DM

description: Sample name: 400136DM


title: OPGP Sample 400173KP

description: Sample name: 400173KP


title: OPGP Sample 400140WM

description: Sample name: 400140WM


title: OPGP Sample 400128MJ

description: Sample name: 400128MJ


title: OPGP Sample 400131CM

description: Sample name: 400131CM


title: OPGP Sample 400130HA

description: Sample name: 400130HA


title: OPGP Sample 400177CG

description: Sample name: 400177CG


title: OPGP Sample 400127MD

description: Sample name: 400127MD


title: OPGP Sample 400122PL

description: Sample name: 400122PL


title: OPGP Sample 400148MS

description: Sample name: 400148MS


title: OPGP Sample 400132HN

description: Sample name: 400132HN


title: OPGP Sample 400145BL

description: Sample name: 400145BL


title: OPGP Sample 400123WN

description: Sample name: 400123WN


title: OPGP Sample 400121PL

description: Sample name: 400121PL


title: OPGP Sample 400152MR

description: Sample name: 400152MR


title: OPGP Sample 400124FR

description: Sample name: 400124FR


title: OPGP Sample 400107MJ

description: Sample name: 400107MJ


title: OPGP Sample 400109LJ

description: Sample name: 400109LJ


title: OPGP Sample 400108BJ

description: Sample name: 400108BJ


title: OPGP Sample 400094RS

description: Sample name: 400094RS


title: OPGP Sample 400110MD

description: Sample name: 400110MD


title: OPGP Sample 400093BL

description: Sample name: 400093BL


title: OPGP Sample 400106PC

description: Sample name: 400106PC


title: OPGP Sample 400105BB

description: Sample name: 400105BB


title: OPGP Sample 400114GR

description: Sample name: 400114GR


title: OPGP Sample 400083TG

description: Sample name: 400083TG


title: OPGP Sample 400101EH

description: Sample name: 400101EH


title: OPGP Sample 400084DM

description: Sample name: 400084DM


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 6

city: Maastricht

first: Wim

last: Van den Hof

address: Universiteitssingel 50

department: Toxicogenomics

country: Netherlands

institute: Maastricht University

hyb_protocol: 12.5µg of cRNA were hybridized for 16 hr on 45°C on Affymetrix Mouse Genome 430 2.0 Array, using Affymetrix® GeneChip® Fluidics Station 450 and the GeneChip Hybridization, Wash and Stain Kit

scan_protocol: Arrays were scanned using Affymetrix GeneArray scanner.

data_processing:
Obtained data sets were re-annotated to the MBNI Custom CDF-files v15.1 (http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/genomic_curated_CDF.asp) (Dai et al., 2005) and RMA normalized (Irizarry et al., 2003) using the Arrayanalysis.org web service.
The 'complete_data.txt' (of 17,370 data rows) contains ~60 of control probes, which are not included in the sample data table.

organism: Mus musculus

source_name: primary mouse hepatocytes_0.5 % v/v DMSO for 48h

label_protocol: Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 250ng total RNA using the 3’ IVT express kit

growth_protocol: Primary Mouse Hepatocytes were cultured in 6-well plates in a collagen-collagen sandwich and in the presence of serum-free culture medium supplemented with glucagon (7ng/mL), insulin (0.5 U/mL), 2% penicillin/streptomycin and hydrocortison (7.5 µg/mL). The cells were incubated at 37 C and 5% CO2.

extract_protocol: Total RNA was isolated after 24 and 48 hours of incubation with CsA or DMSO in HepG2 total RNA was isolated from cells using miRNeasy mini Kit (Qiagen Westburg bv, Leusden, the Netherlands) according to the manufacturer’s instructions and followed by a DNAse I (Qiagen Inc.) treatment. RNA quantity was measured on a spectrophotometer and quality was determined on a BioAnalyzer (Agilent Technologies, Breda, the Netherlands). Only RNA samples which showed clear 18S and 28S peaks and with a RIN level higher than 8 were used.

treatment_protocol: After the recovery period (40-42 hours), the medium was replaced with fresh medium containing either compound or solvent (0.5% DMSO)

tag: strain background

value: primary mouse hepatocytes

tag: exposed to

value: 0.5 % v/v DMSO for 48h


title: OPGP Sample 400113LD

description: Sample name: 400113LD


title: OPGP Sample 400103BN

description: Sample name: 400103BN


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 5


title: OPGP Sample 400082SD

description: Sample name: 400082SD


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 4


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 3


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 2


title: OPGP Sample 400091BS

description: Sample name: 400091BS


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 1


title: OPGP Sample 400070PC

description: Sample name: 400070PC


title: OPGP Sample 400079AP

description: Sample name: 400079AP


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 6

source_name: primary mouse hepatocytes_0.5 % v/v DMSO for 24h

value: 0.5 % v/v DMSO for 24h


title: OPGP Sample 400072GR

description: Sample name: 400072GR


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 5


title: OPGP Sample 4000657TM

description: Sample name: 4000657TM


title: OPGP Sample 400077EB

description: Sample name: 400077EB


title: OPGP Sample 400068PW

description: Sample name: 400068PW


title: OPGP Sample 400076LC

description: Sample name: 400076LC


title: OPGP Sample 400075MR

description: Sample name: 400075MR


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 4


title: OPGP Sample 400073HT

description: Sample name: 400073HT


title: OPGP Sample 400066MA

description: Sample name: 400066MA


title: OPGP Sample 400069CN

description: Sample name: 400069CN


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 3


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 48h, biological rep 3

source_name: primary mouse hepatocytes_10 uM Cyclosporin A for 48h

value: 10 uM Cyclosporin A for 48h


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 48h, biological rep 3

source_name: primary mouse hepatocytes_50 uM Cyclosporin A for 48h

value: 50 uM Cyclosporin A for 48h


title: OPGP Sample 400064WJ

description: Sample name: 400064WJ


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 48h, biological rep 2


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 1


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 48h, biological rep 2


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 48h, biological rep 1


title: OPGP Sample 400051MR_1

description: Sample name: 400051MR_1


title: OPGP Sample 400063BR

description: Sample name: 400063BR


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 24h, biological rep 2

source_name: primary mouse hepatocytes_50 uM Cyclosporin A for 24h

value: 50 uM Cyclosporin A for 24h


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 2


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 6

hyb_protocol: RNA was labeled using the Agilent miRNA Complete Labeling and Hyb Kit (Agilent Technologies, Netherlands) according to the manufacturer’s protocol.

scan_protocol: Arrays were scanned using the Agilent Technologies Scanner. To quantify the signals, the images were processed to TXT files through the  Feature Extraction Software v10.7.3.1 from Agilent Technologies.

data_processing: The arrays were imported in R 2.15.2 (http://www.r-project.org) for quality control with an in-house developed pipeline and all but 1 microarrays were of high quality. The bad quality array and the array containing the paired sample were removed from further analyses. Further downstream analysis was performed by means of AgiMicroRna (Lopez-Romero, 2011) and the intensities were log2 transformed and quantile normalized.

source_name: Primary Mouse Hepatocytes_0.5 % v/v DMSO for 48h

growth_protocol: Primary Mouse Hepatocytes were cultured in 6-well plates in the presence of minimal essential medium (MEM) supplemented with 1% non-essential amino acids, 1% sodium-pyruvate, 2% penicillin/streptomycin and 10% fetal bovine serum (FBS) (all from Gibco BRL, Breda, The Netherlands). The cells were incubated at 37 C and 5% CO2.

extract_protocol: Total RNA was isolated after 24 and 48 hours of incubation with CsA or DMSO, total RNA was isolated from cells using miRNeasy mini Kit (Qiagen Westburg bv, Leusden, the Netherlands) according to the manufacturer’s instructions and followed by a DNAse I (Qiagen Inc.) treatment. RNA quantity was measured on a spectrophotometer and quality was determined on a BioAnalyzer (Agilent Technologies, Breda, the Netherlands). Only RNA samples which showed clear 18S and 28S peaks and with a RIN level higher than 8 were used.

treatment_protocol: When the HepG2 cells were 80% confluent, the medium was replaced with fresh medium containing either compound or solvent (0.5% DMSO)


title: Female#1 Brain

type: SRA

city: Boston

first: Muhammad

middle: B

last: Ekram

state: MA

address: 450 Brookline Avenue, DA 740A

department: Medical Oncology

institute: Dana-Farber Cancer Institute

library_source: genomic

data_processing:
Library strategy: Targeted Repeat Element Bisulfite Sequencing (HT-TREBS)
Basecalls and initial quality filtering were performed by the Ion Torrent Server (v3.4.1).
Reads in the fastq files were filtered to remove any sequence less than 40bp in length.  This removed any short and redundant seqeunce that may not have enough lengths of the non-repeat unique sequence and the IAPLTR sequence.  The filtered reads were mapped to a curated reference genome using the aligner Bowtie 2 with the following configurations: --local, --sensitive-local, -M 2.  This curated genome is made up of bisulfite-converted top (Original Top: OT) and the bottom (Original Bottom: OB) strands of the IAPLTR sequences (along with the 350-bp flanking sequences) and the complementary sequences to those sequences (Complementary to Original Top: CTOT; Complementary to Original Bottom: CTOB).  The original IAPLTR and their flanking sequences were obtained from the mm9 version of the mouse genome.
The mapped reads were then filtered using custom Python scripts to extract only the sequences that had been mapped to the IAPLTR regions and also had at least 10 bases of the flanking unique sequences to ensure the reads were generated from a specific IAPLTR locus.
The filtered reads from each sample were separately analyzed using the BiQ Analyzer HT tool to derive the CpG methylation status of each IAPLTR locus and also other relevant information regarding the quality of the reads.
Genome_build: mm9
Supplementary_files_format_and_content: Bedgraph files were generated using custom script.  Values in the data value column (fourth column) represent the methylation fraction of the cytosine that has been refered to by the coordinates.

source_name: Female#1 Brain

growth_protocol: Tissues from wild-type, postnatal day 7 C57BL/6N littermates were were harvested.

extract_protocol:
Tissues were harvested and lysed using tail lysis buffer containing Proteinase K.  Genomic DNA was isolated and purified using the phenol–chloroform extraction method (Sigma-Aldrich, Cat# P2069).
Briefly, 1µg of the isolated genomic DNA was sonicated to fragments with their average size being 700 bp in length (Bioruptor NGS, Diagenode).  Since the average lengths of IAPLTR are 300-350 bp in length and the desired sequences need to contain non-repeat flanking sequences, the optimum size of the fragments are empirically determined to be around 700 bp in length.  The fragmented DNA was immediately end-repaired using the NEB Next End Repair Module (New England BioLabs), and then ligated to custom-made duplex Ion Torrent ‘A’ adaptors using T4 DNA ligase (New England BioLabs).  In these adaptors, all the Cs have been methylated (Integrated DNA Technologies).  The adaptor-ligated DNA fragments were size-selected to remove any fragment smaller than 300 bp in length using the Agencourt AMPure XP beads (Beckman Coulter).  The size and quantity of the selected fragments were analyzed using the Agilent 2100 Bioanalyzer.  The adaptor-ligated DNA library was modified using the bisulfite conversion reaction according to the manufacturer’s protocol (EZ DNA methylation kit, Zymo Research).  The bisulfite-converted ‘A’ adaptor-ligated library was used as a template for a round of PCR (Maxime PCR Premix Kit, Intron Biotech).  In this PCR, the forward primer (CCATCTCATCCCTGCGTGTCTCCGACTCAG) was designed to bind to the 5’-end of the ‘A’ adaptor region whereas the reverse primer was designed to bind to the 24-bp conserved region among the consensus sequences of the IAPLTR subtypes (IAPLTR1, IAPLTR1a, IAPLTR2, IAPLTR2a, and IAPLTR2b).  The 5’-end of the reverse primer also had the sequence of the regular Ion Torrent ‘P1’ adaptor (CCACTACGCCTCCGCTTTCCTCTCTATGGGCAGTCGGTGAT^CTCCCTAATTAACTACAACCCATC).  The break in the reverse primer sequence indicates the joining point of the P1 adaptor sequence and the IAPLTR-specific sequence.  The amplification cycle number of PCR was individually determined for each of the twelve samples so that the minimum possible cycles were used to generate just enough amount of the PCR product for sequencing.  The PCR product was size-selected for a range of 250-300 bp in length using agarose gel electrophoresis.  The size-selected PCR product was verified for its length and quantity using the Agilent 2100 Bioanalyzer.  Finally, each of the twelve PCR products was individually sequenced in the Ion Personal Genome Machine (PGM) Sequencer using Ion 318 Chips (Ion Torrent, Life Technologies).

value: Female

tag: genotype/variation

value: wild-type

value: Postnatal day 7

value: Whole brain


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 24h, biological rep 2

source_name: primary mouse hepatocytes_10 uM Cyclosporin A for 24h

value: 10 uM Cyclosporin A for 24h


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 48h, biological rep 1


title: OPGP Sample 400053LE

description: Sample name: 400053LE

value: lymphoblastoid cell line

value: female


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 24h, biological rep 1


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 24h, biological rep 1

data_processing:
Obtained data sets were re-annotated to the MBNI Custom CDF-files v15.1 (http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/genomic_curated_CDF.asp) (Dai et al., 2005) and RMA normalized (Irizarry et al., 2003) using the Arrayanalysis.org web service.
The 'complete_data.txt' (of 17,370 data rows) contains ~60 of control probes, which are not included in the sample data table.
The 'complete_data.txt' (of 17,370 data rows) contains ~60 of control probes, which are not included in the sample data table.


title: OPGP Sample 400059SV

description: Sample name: 400059SV

value: European


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 4

label_protocol: RNA was labeled using the Agilent miRNA Complete Labeling and Hyb Kit (Agilent Technologies, Netherlands) according to the manufacturer’s protocol.


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 5


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 3


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 2


title: T4 revert - Tyrphostin AG 1478

city: Pittsburgh

first: Ankur

last: Parikh

address: 5000 Forbes Ave.

institute: CMU

description: cells grown in 3D lrECM

hyb_protocol: standard Affymetrix protocol

scan_protocol: standard Affymetrix protocol

data_processing: The data from the perfect match (PM) probes was first log2-transformed, and normalized using the Cyclic Loess normalization method to minimize unwanted noise in the data. We did not use the difference between PM values and values from the mismatch (MM) probes (i.e., PM – MM) to represent values of probes for each gene, because it has been shown that MM values can pick up both non-specific and specific signal of the probes, and thus PM-MM values can attenuate real signal values from PM. The normalized PM values was then summarized into gene expression values using the median polish technique.

source_name: reverted breast cell, EGFR inhibitor

label_protocol: standard Affymetrix protocol

extract_protocol: Trizol

tag: cell line

tag: treatment

value: Tyrphostin AG 1478

tag: tumor stage

value: revert


title: OPGP Sample 400060MC

description: Sample name: 400060MC


title: T4 revert - AIIB2

description: cells grown in 3D lrECM

source_name: reverted breast cell, beta1-integrin inhibitor


title: OPGP Sample 400043HC

description: Sample name: 400043HC

value: Asian


title: OPGP Sample 400044HS

description: Sample name: 400044HS


title: OPGP Sample 400047DS

description: Sample name: 400047DS


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 48h, biological rep 1

value: primary mouse hepatocytes


title: T4 revert - PD98059

description: cells grown in 3D lrECM

source_name: reverted breast cell, MAPK inhibitor


title: T4 revert - TNF protease inhibitor–2

description: cells grown in 3D lrECM

source_name: reverted breast cell, TNF protease inhibitor–2

value: TNF protease inhibitor–2


title: OPGP Sample 400038CK

description: Sample name: 400038CK

value: male


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 6

source_name: Primary Mouse Hepatocytes_0.5 % v/v DMSO for 24h

value: 0.5 % v/v DMSO for 24h


title: S1 sample 3

description: cells grown in 3D lrECM

source_name: breast cell

value: normal


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 24h, biological rep 3


title: OPGP Sample 400033KC

description: Sample name: 400033KC


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 4


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 3


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 1


title: OPGP Sample 400050RL

description: Sample name: 400050RL


title: OPGP Sample 400030WD

description: Sample name: 400030WD


title: OPGP Sample 400040CN

description: Sample name: 400040CN


title: Primary Mouse Hepatocytes exposed to 0.5 % v/v DMSO for 24h, biological rep 5


title: OPGP Sample 400061DE

description: Sample name: 400061DE


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 48h, biological rep 3

source_name: Primary Mouse Hepatocytes_10 uM Cyclosporin A for 48h

value: 10 uM Cyclosporin A for 48h


title: OPGP Sample 400032RC

description: Sample name: 400032RC


title: OPGP Sample 400041LJ

description: Sample name: 400041LJ


title: OPGP Sample 400022WA

description: Sample name: 400022WA


title: T4 revert - mAb225

description: cells grown in 3D lrECM

source_name: reverted breast cell, EGFR inhibitors


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 24h, biological rep 3

value: 50 uM Cyclosporin A for 24h


title: OPGP Sample 400021ME_1

description: Sample name: 400021ME_1

source_name: lymphoblastoid cell line


title: OPGP Sample 400013TA

description: Sample name: 400013TA


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 48h, biological rep 3

source_name: Primary Mouse Hepatocytes_50 uM Cyclosporin A for 48h

value: 50 uM Cyclosporin A for 48h


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 48h, biological rep 2


title: OPGP Sample 400014SL

description: Sample name: 400014SL


title: Scnn1b-Transgenic 2

city: Heidelberg

first: Raman

last: Agrawal

state: BW

address: Im Neuenheimer Feld 350

department: Translational Lung Research Center

country: Germany

institute: Heidelberg University

data_processing: GeneSpring software GX (Agilent Technologies), RMA normalization

source_name: Lung

label_protocol: Whole Transcript (WT) Sense Target Labeling (Affymetrix)

extract_protocol: Trizol extraction of total RNA was performed according to the manufacturer's instructions.

tag: genotype

tag: tissue

value: lung

tag: genetic background


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 48h, biological rep 2


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 48h, biological rep 1


title: Scnn1b-Transgenic 3


title: T4 revert - dominant-negative Rap1

description: cells grown in 3D lrECM

source_name: reverted breast cell, dominant-negative Rap1

value: dominant-negative Rap1


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 48h, biological rep 1


title: Wild Type 1

value: wild type


title: Wild Type 3


source_name: Primary Mouse Hepatocytes_10 uM Cyclosporin A for 24h

value: 10 uM Cyclosporin A for 24h


title: Scnn1b-Transgenic 1


title: Wild Type 2


title: High Grade Astrocytoma 103 - Tumour-250Ksnp

first: Pawel

last: Buczkowicz

department: Paediatric Laboratory Medicine

institute: Hospital for Sick Children

description: Hybridized to 250K

hyb_protocol: DNA was restriction digested, PCR amplified, fragmented, labeled and hybridized to each array according to the manufacturer's instructions.

scan_protocol: The Arrays were then washed using Affymetrix fluidics stations, and scanned using the Gene Chip Scanner 3000.

data_processing: primary_data_description: Genotype Call (SNP call): AA, AB, BB, NC, and NoCall; 'Signal' = Summarized signal

source_name: High Grade Astrocytoma 103 - Tumour

label_protocol: As per manufacturer (Affymetrix)

extract_protocol: Genomic DNA was extracted from snap frozen biopsy and surgical samples from paediatric high grade glioma patients using the acidic phenol-chloroform method. DNA quality and quantity was assessed using a Nanodrop Spectrophotometer and agarose gel electrophoresis.

tag: histology

value: glioblastoma


source_name: Primary Mouse Hepatocytes_50 uM Cyclosporin A for 24h


title: High Grade Astrocytoma 91 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 91 - Tumour


title: High Grade Astrocytoma 101 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 101 - Tumour


title: High Grade Astrocytoma 92 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 92 - Tumour


title: High Grade Astrocytoma 94 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 94 - Tumour


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 24h, biological rep 2


title: High Grade Astrocytoma 98 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 98 - Tumour


title: High Grade Astrocytoma 99 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 99 - Tumour


title: High Grade Astrocytoma 93 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 93 - Tumour


title: High Grade Astrocytoma 90 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 90 - Tumour


title: Primary Mouse Hepatocytes exposed to 50 uM Cyclosporin A for 24h, biological rep 2


title: High Grade Astrocytoma 100 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 100 - Tumour


title: High Grade Astrocytoma 89 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 89 - Tumour


title: High Grade Astrocytoma 95 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 95 - Tumour


title: T4 revert - LY294002

description: cells grown in 3D lrECM

source_name: reverted breast cell, PI3K inhibitor


title: T4 revert - MMPs and ADAMs

description: cells grown in 3D lrECM

source_name: reverted breast cell, MMP and ADAMS inhibitor

value: MMPs and ADAMs


title: High Grade Astrocytoma 102 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 102 - Tumour


title: Primary Mouse Hepatocytes exposed to 10 uM Cyclosporin A for 24h, biological rep 1

source_name: Primary Mouse Hepatocytes_10 uM Cyclosporin A for 24h


title: T4 revert - GM6001

description: cells grown in 3D lrECM

source_name: reverted breast cell,  MMP inhibitor


title: High Grade Astrocytoma 97 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 97 - Tumour


title: High Grade Astrocytoma 87 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 87 - Tumour


title: High Grade Astrocytoma 13b - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 13b - Tumour


title: High Grade Astrocytoma 88 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 88 - Tumour


title: High Grade Astrocytoma 14a - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 14a - Tumour


title: High Grade Astrocytoma 19 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 19 - Tumour

value: anaplastic astrocytoma


title: T4 sample 3

description: cells grown in 3D lrECM

source_name: malignant breast cell

value: malignant


title: High Grade Astrocytoma 86 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 86 - Tumour


title: High Grade Astrocytoma 96 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 96 - Tumour


title: High Grade Astrocytoma 45a - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 45a - Tumour


title: High Grade Astrocytoma 57 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 57 - Tumour


title: High Grade Astrocytoma 18 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 18 - Tumour


title: S1 sample 1

description: cells grown in 3D lrECM

source_name: breast cell


title: S1 sample 2

description: cells grown in 3D lrECM


title: T4 sample 2

description: cells grown in 3D lrECM


title: T4 sample 1

description: cells grown in 3D lrECM


title: High Grade Astrocytoma 12 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 12 - Tumour


title: High Grade Astrocytoma 11 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 11 - Tumour


title: High Grade Astrocytoma 10 - Tumour-250Knsp

description: Hybridized to 250K

source_name: High Grade Astrocytoma 10 - Tumour


title: MiR-21 knockout replicate 2

status: Public on Jul 23 2014

city: Charlottesville

first: Yong

last: Huang

state: VA

address: 1340 Jefferson Park Ave

department: Medicine

institute: University of Viginia

hyb_protocol: Hybridized to Illumina MouseRef-8 v2.0 expression beadchip.

scan_protocol: not provided

data_processing: raw data were processed using the R/Bioconductor package limma for background correction and quantile normalization

label_protocol: not provided

treatment_protocol: MiR-21-/- (21KO) mice on C57BL/6 background were kindly provided by Dr. Eric Olson (Patrick, et al. J Clin Invest. 2010;120:3912-3916.). The miR-21-/- mice do not develop spontaneous colitis.  Gene expression profiles were established for normal miR-21-/- mice and wild type c57BL/6 mice (WT) from Taconic Farm Inc. (Hudson, NY)

value: colon mucosa

tag: strain

value: MiR-21 knockout

tag: group