title: cy84_Met_CD45_pos_A11_S875_comb


title: cy94_cd45pos_C05_S125_comb

status: Public on Nov 01 2018

type: SRA

city: Cambridge

first: Orr

last: Ashenberg

state: MA

address: 415 Main Street

department: Klarman Cell Observatory

country: USA

institute: Broad Institute

description:
Full-length RNAseq (SMART-Seq2) reads.
processed data file: counts.csv
processed data file: tpm.csv
processed data file: cell.annotations.csv

library_source: transcriptomic

data_processing:
Full-length RNAseq (SMART-Seq2).
Tophat
Bowtie mapping to UCSC hg19 human transcriptome.
RSEM v1.2.8
Genome_build: hg19 (GRCh37)
Supplementary_files_format_and_content: cell.annotations.csv: Comma-separated cell sample annotation table; For each cell (row): cell name, sample type, cell type, treatment group, cohort, number of genes, number of reads.
Supplementary_files_format_and_content: counts.csv: Comma-separated counts table; Full-length RNAseq (SMART-Seq2); The expression levels for each gene (rows) in each single cell (column) in counts as calculated using RSEM.
Supplementary_files_format_and_content: tpm.csv: Comma-separated log-transformed transcripts per million (TPM) table; Values are provided as log2[(TPM/10) +1]; Full-length RNAseq (SMART-Seq2); The expression levels for each gene (rows) in each single cell (column) in transcripts per million (TPM) as calculated using RSEM.

molecule: total RNA

organism: Homo sapiens

source_name: melanoma tumor

extract_protocol:
Dissociated individual cells from fresh tumor resections. Isolated immune and non-immune cells by FACS based on CD45 staining.
Full-length RNAseq (SMART-Seq2) libraries sequenced with 38bp paired-end reads on an Illumina NextSeq 500.

tag: tumor-of-origin

tag: treatment-group

tag: cohort

value: Tirosh

tag: cell type


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_C12_S420_comb


title: cy58_1_CD45_pos_D09_S621_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_A02_S194_comb


title: CY89A_Core_15_B07_S19_comb


title: Cy81_FNA_CD45_C04_S220_comb


title: cy80_CD45_pos_PD1_pos_H02_S182_comb


title: CY94CD45POS_1_G01_S169_comb


title: cy60_1_cd_45_pos_HC_pos_HLDAR_pos_D12_S1008_comb


title: cy88_cd_45_pos_3_H08_S668_comb


title: cy84_Primary_CD45_pos_D09_S429_comb


title: CY88CD45_150813_B05_S305_comb_7


title: CY89A_CD45_POS_10_E11_S251_comb


title: cy84_Met_CD45_pos_A04_S868_comb


title: CY84_PRIM_POS_ALL_8_B08_S116_comb


title: cy60_1_cd_45_pos_4_B09_S21_comb


title: cy79_p4_CD45_pos_PD1_pos_G10_S370_comb


title: CY75_1FNA_H03_S567_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_F07_S259_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_C09_S417_comb


title: cy88_cd_45_pos_G11_S467_comb


title: cy60_1_cd_45_pos_3_D06_S330_comb


title: cy80_CD45_pos_PD1_pos_D03_S135_comb


title: cy88_cd_45_pos_3_B11_S599_comb


title: cy58_1_CD45_pos_G12_S660_comb


title: cy72_CD45_pos_C01_S889_comb


title: cy80_Cd45_pos_Pd1_neg_S217_B01_S217_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D06_S234_comb


title: cy74_CD45_pos_D04_S712_comb


title: cy74_CD45_pos_A03_S675_comb


title: cy58_1_CD45_pos_G08_S656_comb


title: cy79_p4_CD45_pos_PD1_pos_B02_S302_comb


title: CY89COREQ1_G05_S365_comb


title: CY94CD45POS_1_B03_S111_comb


title: cy53_1_CD45_pos_1_G05_S77_comb


title: CY89COREQ1_E12_S348_comb


title: cy79_p4_CD45_pos_PD1_pos_B04_S304_comb


title: cy72_CD45_pos_B05_S881_comb


title: cy80_Cd45_pos_Pd1_neg_S344_G08_S344_comb


title: cy79_p4_CD45_pos_PD1_pos_C07_S319_comb


title: cy80_CD45_pos_PD1_pos_F08_S164_comb


title: cy72_CD45_pos_C03_S891_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G12_S276_comb


title: cy84_Met_CD45_pos_G09_S945_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_A12_S396_comb


title: cy80_CD45_neg_A03_S387_comb


title: cy80_Cd45_pos_PD1_pos_A11_S23_comb


title: cy60_1_cd_45_pos_3_F11_S359_comb


title: cy80_Cd45_pos_Pd1_neg_S249_C09_S249_comb


title: CY89A_CD45_POS_6_A12_S108_comb


title: cy80_Cd45_pos_Pd1_neg_S347_G11_S347_comb


title: cy79_p4_CD45_pos_PD1_pos_G09_S369_comb


title: cy58_1_CD45_pos_C03_S603_comb


title: cy80_Cd45_pos_PD1_pos_S164_G08_S164_comb


title: CY58_1_CD45_F07_S1027_comb


title: Cy74_CD45_E09_S441_comb


title: Cy74_CD45_G06_S462_comb


title: cy53_1_CD45_pos_1_A10_S10_comb


title: cy79_p4_CD45_pos_PD1_pos_B09_S309_comb


title: CY88CD45_150813_H11_S383_comb


title: CY58_1_CD45_B04_S976_comb


title: cy82_CD45_pos_2_A02_S482_comb


title: cy79_p5_CD45_pos_PD1_pos_F11_S647_comb


title: cy84_Primary_CD45_pos_H03_S471_comb


title: Cy74_CD45_C04_S412_comb


title: cy94_cd45pos_H06_S186_comb


title: CY75_1FNA_A12_S492_comb


title: cy60_1_cd_45_pos_3_G11_S371_comb


title: cy79_p4_CD45_pos_PD1_pos_E10_S346_comb


title: cy79_p5_CD45_pos_PD1_pos_E11_S635_comb


title: cy58_1_CD45_pos_A06_S582_comb


title: cy79_p5_CD45_pos_PD1_pos_B06_S594_comb


title: cy74_CD45_pos_G05_S749_comb


title: CY89A_CD45_POS_6_E04_S148_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_E09_S441_comb


title: Cy72_CD45_C05_S701_comb


title: cy80_CD45_pos_PD1_pos_D04_S136_comb


title: cy79_p3_CD45_pos_PD1_neg_E06_S150_comb


title: CY94CD45POS_1_B04_S112_comb


title: cy74_CD45_pos_F10_S742_comb


title: Cy74_CD45_D06_S426_comb


title: cy72_CD45_pos_B08_S884_comb


title: cy53_1_CD45_pos_1_C02_S26_comb


title: CY75_1FNA_F12_S552_comb


title: cy88_cd_45_pos_C02_S410_comb


title: cy79_p5_CD45_pos_PD1_pos_F01_S637_comb


title: cy79_p5_CD45_pos_PD1_pos_F07_S643_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_C06_S222_comb


title: cy94_cd45pos_4_B11_S23_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F11_S455_comb


title: cy79_p4_CD45_pos_PD1_pos_B01_S301_comb


title: cy79_p3_CD45_pos_PD1_neg_A07_S103_comb


title: CY84_PRIM_POS_ALL_6_C04_S412_comb


title: cy53_1_CD45_pos_1_A04_S4_comb


title: Cy74_CD45_C01_S409_comb


title: CY58_1_CD45_B03_S975_comb


title: cy94_cd45pos_F10_S166_comb


title: cy79_p5_CD45_pos_PD1_pos_E05_S629_comb


title: cy72_CD45_pos_D06_S906_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B05_S401_comb


title: CY75_1FNA_F06_S546_comb


title: cy53_1_CD45_pos_2_B02_S974_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_B05_S209_comb


title: CY89A_Core_15_B11_S23_comb


title: cy53_1_CD45_pos_1_H10_S94_comb


title: cy53_1_CD45_pos_1_F12_S72_comb


title: cy84_Met_CD45_pos_G07_S943_comb


title: CY89A_CD45_POS_10_G09_S273_comb


title: cy80_CD45_pos_PD1_pos_G12_S180_comb


title: CY75_1FNA_F04_S544_comb


title: CY58_1_CD45_B12_S984_comb


title: cy74_CD45_pos_C10_S706_comb


title: CY89A_CD45_POS_6_G05_S173_comb


title: cy60_1_cd_45_pos_3_C08_S320_comb


title: cy94_cd45pos_4_A10_S10_comb


title: cy80_Cd45_pos_PD1_pos_S111_E03_S111_comb


title: cy94_cd45pos_4_D10_S46_comb


title: cy94_cd45pos_4_D09_S45_comb


title: cy84_Primary_CD45_pos_G10_S466_comb


title: cy53_1_CD45_pos_2_E05_S1013_comb


title: cy72_CD45_pos_G12_S948_comb


title: cy82_CD45_pos_2_A10_S490_comb


title: cy79_p4_CD45_pos_PD1_pos_B08_S308_comb


title: cy80_CD45_neg_D09_S429_comb


title: cy80_Cd45_pos_PD1_pos_D07_S91_comb


title: CY89A_CD45_POS_10_G11_S275_comb


title: cy80_Cd45_pos_PD1_pos_D08_S92_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G05_S269_comb


title: cy80_Cd45_pos_PD1_pos_S139_F07_S139_comb


title: cy79_p5_CD45_pos_PD1_pos_C06_S606_comb


title: CY88CD45POS_2_G09_S465_comb


title: cy60_1_cd_45_pos_3_D11_S335_comb


title: CY89FNA_F07_S259_comb


title: CY75_1FNA_F10_S550_comb


title: cy72_CD45_pos_H03_S951_comb


title: cy79_p5_CD45_pos_PD1_pos_G09_S657_comb


title: CY58_1_CD45_H01_S1045_comb


title: CY75_1FNA_E03_S531_comb


title: cy60_1_cd_45_pos_4_H09_S93_comb


title: cy79_p4_CD45_pos_PD1_pos_A11_S299_comb


title: cy94_cd45neg_cd90pos_G08_S368_comb


title: CY88CD45POS_7_D07_S235_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_E10_S538_comb


title: cy58_1_CD45_pos_F05_S641_comb


title: Cy72_CD45_G02_S746_comb


title: cy79_p4_CD45_pos_PD1_pos_B12_S312_comb


title: cy74_CD45_pos_B07_S691_comb


title: CY88CD45POS_2_C09_S417_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_C03_S219_comb


title: Cy81_FNA_CD45_B05_S209_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_C09_S225_comb


title: cy80_Cd45_pos_PD1_pos_B04_S40_comb


title: CY75_1FNA_A05_S485_comb_6


title: cy94_cd45pos_4_H10_S94_comb


title: cy53_1_CD45_pos_2_H02_S1046_comb


title: cy94_cd45pos_D09_S141_comb


title: cy74_CD45_pos_F08_S740_comb


title: cy79_p5_CD45_pos_PD1_pos_H12_S672_comb


title: cy84_Primary_CD45_pos_B12_S408_comb


title: Cy74_CD45_D02_S422_comb


title: CY88CD45POS_7_C09_S225_comb


title: cy94_cd45pos_4_E06_S54_comb


title: CY88CD45POS_2_F03_S447_comb


title: cy72_CD45_pos_B12_S888_comb


title: CY89A_CD45_POS_10_H01_S277_comb


title: Cy74_CD45_H11_S479_comb


title: cy74_CD45_pos_C08_S704_comb


title: cy79_p4_CD45_pos_PD1_pos_C03_S315_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_D01_S421_comb


title: cy74_CD45_pos_C06_S702_comb


title: cy79_p5_CD45_pos_PD1_pos_C12_S612_comb


title: cy80_Cd45_pos_PD1_pos_S113_E05_S113_comb


title: Cy81_FNA_CD45_A04_S196_comb


title: cy80_Cd45_pos_PD1_pos_S181_H01_S181_comb


title: CY75_1FNA_F07_S547_comb_5


title: cy80_CD45_neg_D11_S431_comb


title: cy94_cd45pos_B03_S111_comb


title: cy94_cd45neg_cd90pos_B02_S302_comb


title: cy84_Met_CD45_pos_C07_S895_comb


title: cy79_p4_CD45_pos_PD1_pos_H05_S377_comb


title: cy94_cd45pos_A02_S98_comb


title: CY94CD45POS_1_C10_S130_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B09_S405_comb


title: cy53_1_CD45_pos_2_C06_S990_comb


title: cy80_CD45_pos_PD1_pos_C02_S122_comb


title: CY89A_Core_15_D08_S44_comb


title: Cy81_FNA_CD45_G12_S276_comb


title: Cy81_FNA_CD45_D04_S232_comb


title: CY75_1FNA_H11_S575_comb


title: CY89FNA_B08_S212_comb


title: CY89COREQ1_D02_S326_comb


title: Cy71_CD45_C06_S510_comb


title: CY89A_Core_15_D09_S45_comb


title: cy88_cd_45_pos_3_F04_S640_comb


title: cy84_Primary_CD45_pos_C10_S418_comb


title: cy94_cd45pos_4_A05_S5_comb


title: Cy71_CD45_E01_S529_comb


title: cy72_CD45_pos_A10_S874_comb


title: CY89COREQ1_D12_S336_comb


title: cy58_1_CD45_pos_E06_S630_comb


title: CY88CD45POS_2_B05_S401_comb


title: cy80_CD45_pos_PD1_pos_C10_S130_comb


title: cy94_cd45pos_4_E05_S53_comb


title: cy60_1_cd_45_pos_3_C11_S323_comb


title: cy80_CD45_neg_F07_S451_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F02_S446_comb


title: cy60_1_cd_45_pos_3_F02_S350_comb


title: cy58_1_CD45_pos_A08_S584_comb


title: CY88CD45POS_2_G04_S460_comb


title: CY58_1_CD45_G04_S1036_comb


title: CY58_1_CD45_C10_S994_comb


title: cy58_1_CD45_pos_B01_S589_comb


title: cy72_CD45_pos_C09_S897_comb


title: Cy74_CD45_H09_S477_comb


title: cy80_CD45_pos_PD1_pos_E12_S156_comb


title: cy94_cd45pos_A08_S104_comb


title: cy53_1_CD45_pos_1_F09_S69_comb


title: cy80_Cd45_pos_PD1_pos_C05_S65_comb


title: CY89A_Core_15_H08_S92_comb


title: cy79_p5_CD45_pos_PD1_pos_H11_S671_comb


title: cy80_Cd45_pos_PD1_pos_B02_S38_comb


title: cy74_CD45_pos_E10_S730_comb

value: NK


title: cy60_1_cd_45_pos_4_G08_S80_comb


title: cy80_CD45_neg_C01_S409_comb


title: cy53_1_CD45_pos_1_F03_S63_comb


title: cy60_1_cd_45_pos_3_H02_S374_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_G07_S463_comb


title: cy80_Cd45_pos_PD1_pos_C04_S64_comb


title: cy79_p5_CD45_pos_PD1_pos_G11_S659_comb


title: cy80_CD45_pos_PD1_pos_D05_S137_comb


title: cy74_CD45_pos_G01_S745_comb


title: cy80_Cd45_pos_PD1_pos_C01_S61_comb


title: Cy72_CD45_A09_S681_comb


title: cy79_p5_CD45_pos_PD1_pos_G06_S654_comb


title: cy79_p5_CD45_pos_PD1_pos_D11_S623_comb


title: CY94CD45POS_1_D04_S136_comb


title: cy79_p4_CD45_pos_PD1_pos_D05_S329_comb


title: Cy71_CD45_D10_S526_comb


title: cy53_1_CD45_pos_1_C11_S35_comb


title: cy79_p5_CD45_pos_PD1_pos_E07_S631_comb


title: cy94_cd45pos_4_H03_S87_comb


title: cy94_cd45pos_B08_S116_comb


title: cy84_Met_CD45_pos_F04_S928_comb


title: CY89A_Core_15_D10_S46_comb


title: cy58_1_CD45_pos_A12_S588_comb


title: cy80_Cd45_pos_PD1_pos_S117_E09_S117_comb


title: cy79_p4_CD45_pos_PD1_pos_D07_S331_comb


title: cy84_Primary_CD45_pos_G12_S468_comb


title: cy79_p5_CD45_pos_PD1_pos_D08_S620_comb


title: cy79_p3_CD45_pos_PD1_neg_E08_S152_comb


title: cy94_cd45pos_C10_S130_comb


title: CY88CD45_150813_B01_S301_comb


title: Cy81_FNA_CD45_D06_S234_comb


title: cy94_cd45pos_4_H08_S92_comb


title: cy72_CD45_pos_D01_S901_comb


title: cy80_Cd45_pos_PD1_pos_B05_S41_comb


title: Cy74_CD45_A11_S395_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_D08_S428_comb


title: Cy71_CD45_F12_S552_comb


title: CY89A_CD45_POS_10_E12_S252_comb


title: CY84_PRIM_POS_ALL_6_A08_S392_comb


title: cy60_1_cd_45_pos_3_F06_S354_comb


title: cy79_p4_CD45_pos_PD1_pos_E02_S338_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_B10_S214_comb


title: CY58_1_CD45_A02_S962_comb


title: cy72_CD45_pos_C04_S892_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_E12_S444_comb


title: CY89A_Core_15_G03_S75_comb


title: cy94_cd45neg_cd90pos_G12_S372_comb


title: CY88CD45POS_7_E05_S245_comb


title: cy94_cd45neg_cd90pos_F07_S355_comb


title: cy80_Cd45_pos_PD1_pos_B03_S39_comb


title: CY58_1_CD45_G07_S1039_comb


title: cy72_CD45_pos_G06_S942_comb


title: cy58_1_CD45_pos_F06_S642_comb


title: cy74_CD45_pos_D07_S715_comb


title: cy94_cd45pos_G06_S174_comb


title: cy84_Primary_CD45_pos_C04_S412_comb


title: cy88_cd_45_pos_E09_S441_comb


title: cy82_CD45_pos_2_B10_S502_comb


title: cy60_1_cd_45_pos_4_A09_S9_comb


title: cy80_Cd45_pos_PD1_pos_S114_E06_S114_comb


title: cy79_p4_CD45_pos_PD1_pos_H01_S373_comb


title: cy60_1_cd_45_pos_4_D09_S45_comb


title: cy80_CD45_pos_PD1_pos_B01_S109_comb


title: CY94CD45POS_1_D10_S142_comb


title: cy79_p4_CD45_pos_PD1_pos_C02_S314_comb


title: cy53_1_CD45_pos_2_D08_S1004_comb


title: cy80_Cd45_pos_PD1_pos_S158_G02_S158_comb


title: cy72_CD45_pos_E05_S917_comb


title: cy88_cd_45_pos_3_D11_S623_comb


title: Cy71_CD45_H03_S567_comb


title: cy79_p5_CD45_pos_PD1_pos_B05_S593_comb


title: cy79_p5_CD45_pos_PD1_pos_D10_S622_comb


title: cy53_1_CD45_pos_1_B12_S24_comb


title: cy53_1_CD45_pos_2_B04_S976_comb


title: cy72_CD45_pos_F05_S929_comb


title: cy80_CD45_neg_F05_S449_comb


title: CY89A_CD45_POS_10_F02_S254_comb


title: cy79_p3_CD45_pos_PD1_neg_E02_S146_comb


title: cy53_1_CD45_pos_1_G03_S75_comb


title: cy94_cd45pos_H10_S190_comb


title: CY88CD45POS_2_E05_S437_comb


title: cy80_CD45_pos_PD1_pos_E06_S150_comb


title: cy58_1_CD45_pos_H10_S670_comb


title: cy88_cd45pos_5_E05_S245_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B07_S403_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_H11_S287_comb


title: Cy72_CD45_C11_S707_comb


title: cy80_CD45_pos_PD1_pos_G04_S172_comb


title: cy58_1_CD45_pos_C10_S610_comb


title: cy79_p4_CD45_pos_PD1_pos_B06_S306_comb


title: CY58_1_CD45_G06_S1038_comb


title: cy88_cd_45_pos_E03_S435_comb


title: cy79_p3_CD45_pos_PD1_neg_E07_S151_comb


title: Cy81_FNA_CD45_F05_S257_comb


title: Cy71_CD45_D03_S519_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B06_S402_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_G08_S464_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F06_S450_comb


title: Cy72_CD45_G05_S749_comb


title: cy88_cd_45_pos_3_C07_S607_comb


title: Cy72_CD45_G07_S751_comb


title: cy80_CD45_neg_C07_S415_comb


title: cy80_Cd45_pos_PD1_pos_B10_S46_comb


title: cy79_p5_CD45_pos_PD1_pos_B02_S590_comb


title: cy82_CD45_pos_2_D04_S520_comb


title: cy80_Cd45_pos_PD1_pos_A08_S20_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_E08_S536_comb


title: cy74_CD45_pos_F09_S741_comb


title: Cy72_CD45_H09_S765_comb


title: cy88_cd45pos_5_B03_S207_comb


title: cy58_1_CD45_pos_F07_S643_comb


title: Cy74_CD45_D09_S429_comb


title: cy84_Primary_CD45_pos_A01_S385_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D10_S238_comb


title: Cy72_CD45_E03_S723_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_C06_S414_comb


title: cy82_CD45_pos_1_C04_S508_comb


title: cy94_cd45pos_A12_S108_comb


title: cy74_CD45_pos_C01_S697_comb


title: cy72_CD45_pos_E11_S923_comb


title: cy58_1_CD45_pos_C02_S602_comb


title: cy80_Cd45_pos_PD1_pos_D06_S90_comb


title: cy79_p4_CD45_pos_PD1_pos_H02_S374_comb


title: cy80_CD45_neg_B12_S408_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_B04_S208_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_C02_S506_comb


title: CY58_1_CD45_H10_S1054_comb


title: CY88CD45POS_7_D02_S230_comb


title: cy53_1_CD45_pos_1_G04_S76_comb


title: cy79_p5_CD45_pos_PD1_pos_A02_S578_comb


title: cy58_1_CD45_pos_G07_S655_comb


title: cy84_Primary_CD45_pos_C03_S411_comb


title: cy72_CD45_pos_F12_S936_comb


title: cy72_CD45_pos_H02_S950_comb


title: cy79_p4_CD45_pos_PD1_pos_E03_S339_comb


title: cy60_1_cd_45_pos_4_H07_S91_comb


title: CY89A_CD45_POS_6_B01_S109_comb


title: cy79_p5_CD45_pos_PD1_pos_A11_S587_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D03_S231_comb


title: Cy74_CD45_F11_S455_comb


title: cy79_p4_CD45_pos_PD1_pos_H08_S380_comb


title: Cy72_CD45_B11_S695_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_D12_S528_comb


title: cy94_cd45pos_4_H07_S91_comb


title: cy60_1_cd_45_pos_4_A01_S1_comb


title: cy79_p4_CD45_pos_PD1_pos_H12_S384_comb


title: Cy74_CD45_G09_S465_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_F04_S256_comb


title: cy58_1_CD45_pos_E01_S625_comb


title: cy79_p4_CD45_pos_PD1_pos_A07_S295_comb


title: CY88CD45_150813_C09_S321_comb


title: cy74_CD45_pos_B08_S692_comb


title: Cy72_CD45_G10_S754_comb


title: Cy81_FNA_CD45_A11_S203_comb


title: Cy81_FNA_CD45_G06_S270_comb


title: CY58_1_CD45_G01_S1033_comb


title: cy74_CD45_pos_H05_S761_comb


title: cy80_Cd45_pos_PD1_pos_S167_G11_S167_comb


title: CY58_1_CD45_C07_S991_comb


title: cy60_1_cd_45_pos_3_G03_S363_comb


title: CY94CD45POS_1_A01_S97_comb


title: CY84_PRIM_POS_ALL_7_G05_S269_comb


title: cy74_CD45_pos_D06_S714_comb


title: cy80_CD45_pos_PD1_pos_A12_S108_comb


title: cy80_Cd45_pos_PD1_pos_S118_E10_S118_comb


title: cy79_p5_CD45_pos_PD1_pos_H04_S664_comb


title: cy53_1_CD45_pos_1_C12_S36_comb


title: cy79_p3_CD45_pos_PD1_neg_F12_S168_comb


title: cy79_p4_CD45_pos_PD1_pos_D09_S333_comb


title: cy79_p5_CD45_pos_PD1_pos_H01_S661_comb


title: Cy72_CD45_H08_S764_comb


title: CY89A_Core_15_H04_S88_comb


title: CY94CD45POS_1_D01_S133_comb


title: CY58_1_CD45_A08_S968_comb


title: cy80_CD45_neg_G08_S464_comb


title: cy80_Cd45_pos_PD1_pos_D05_S89_comb


title: CY88CD45_150813_D01_S325_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F05_S449_comb


title: cy88_cd_45_pos_F04_S448_comb


title: cy79_p4_CD45_pos_PD1_pos_G04_S364_comb


title: cy79_p4_CD45_pos_PD1_pos_E08_S344_comb


title: Cy71_CD45_H09_S573_comb


title: cy80_CD45_pos_PD1_pos_D01_S133_comb


title: cy53_1_CD45_pos_1_D09_S45_comb


title: cy60_1_cd_45_pos_3_E09_S345_comb


title: cy79_p4_CD45_pos_PD1_pos_A02_S290_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G02_S266_comb


title: cy80_Cd45_pos_Pd1_neg_S299_E11_S299_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G03_S267_comb


title: cy94_cd45pos_4_E11_S59_comb


title: Cy81_FNA_CD45_F07_S259_comb


title: Cy72_CD45_B12_S696_comb


title: cy94_cd45pos_4_B08_S20_comb


title: Cy72_CD45_E01_S721_comb


title: cy79_p4_CD45_pos_PD1_pos_G11_S371_comb


title: CY88CD45POS_7_H03_S279_comb


title: cy94_cd45pos_4_E07_S55_comb


title: cy80_CD45_pos_PD1_pos_G11_S179_comb


title: cy94_cd45neg_cd90pos_D06_S330_comb


title: cy80_Cd45_pos_Pd1_neg_S295_E07_S295_comb


title: cy88_cd45pos_5_E01_S241_comb


title: cy79_p5_CD45_pos_PD1_pos_A08_S584_comb


title: cy79_p5_CD45_pos_PD1_pos_G07_S655_comb


title: cy79_p5_CD45_pos_PD1_pos_D05_S617_comb


title: cy72_CD45_pos_H06_S954_comb


title: cy53_1_CD45_pos_1_F07_S67_comb


title: CY89A_Core_15_D12_S48_comb


title: cy58_1_CD45_pos_H07_S667_comb


title: cy79_p5_CD45_pos_PD1_pos_B03_S591_comb


title: cy53_1_CD45_pos_2_H01_S1045_comb


title: cy79_p4_CD45_pos_PD1_pos_F09_S357_comb


title: cy58_1_CD45_pos_B04_S592_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D01_S229_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_H02_S278_comb


title: cy79_p4_CD45_pos_PD1_pos_A08_S296_comb


title: CY89A_Core_15_B12_S24_comb


title: CY58_1_CD45_G03_S1035_comb


title: CY89A_Core_15_G08_S80_comb


title: cy74_CD45_pos_D10_S718_comb


title: cy58_1_CD45_pos_G06_S654_comb


title: Cy72_CD45_D10_S718_comb


title: cy53_1_CD45_pos_2_A03_S963_comb


title: CY94CD45POS_1_A03_S99_comb


title: cy60_1_cd_45_pos_4_H02_S86_comb


title: cy79_p5_CD45_pos_PD1_pos_C02_S602_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_A11_S395_comb


title: Cy72_CD45_A12_S684_comb


title: cy74_CD45_pos_E08_S728_comb


title: Cy72_CD45_A10_S682_comb


title: CY58_1_CD45_G02_S1034_comb


title: cy79_p4_CD45_pos_PD1_pos_F11_S359_comb


title: cy53_1_CD45_pos_1_E12_S60_comb


title: CY89A_CD45_POS_10_B07_S211_comb


title: cy58_1_CD45_pos_B11_S599_comb


title: CY89FNA_A08_S200_comb


title: Cy81_FNA_CD45_A10_S202_comb


title: cy58_1_CD45_pos_H04_S664_comb


title: cy88_cd_45_pos_F03_S447_comb


title: cy94_cd45pos_B07_S115_comb


title: cy88_cd_45_pos_3_D09_S621_comb


title: cy74_CD45_pos_E05_S725_comb


title: cy80_CD45_pos_PD1_pos_D10_S142_comb


title: cy79_p4_CD45_pos_PD1_pos_F05_S353_comb


title: cy74_CD45_pos_G09_S753_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G04_S268_comb


title: CY58_1_CD45_F06_S1026_comb


title: Cy81_FNA_CD45_B06_S210_comb


title: cy79_p4_CD45_pos_PD1_pos_F10_S358_comb


title: cy88_cd_45_pos_B09_S405_comb


title: cy60_1_cd_45_pos_3_F01_S349_comb


title: cy80_Cd45_pos_PD1_pos_S187_H07_S187_comb


title: cy82_CD45_pos_3_C07_S31_comb


title: CY88CD45POS_7_G02_S266_comb


title: Cy71_CD45_F04_S544_comb


title: CY58_1_CD45_D07_S1003_comb


title: cy94_cd45pos_4_E08_S56_comb


title: cy80_CD45_pos_PD1_pos_E11_S155_comb


title: cy79_p5_CD45_pos_PD1_pos_A03_S579_comb


title: cy88_cd_45_pos_E11_S443_comb


title: cy94_cd45pos_4_G09_S81_comb


title: cy79_p4_CD45_pos_PD1_pos_E11_S347_comb


title: cy80_CD45_neg_C04_S412_comb


title: CY88CD45POS_7_E07_S247_comb


title: cy60_1_cd_45_pos_4_E04_S52_comb


title: cy94_cd45pos_4_G01_S73_comb


title: CY88CD45POS_7_B09_S213_comb


title: Cy71_CD45_E07_S535_comb


title: cy60_1_cd_45_pos_3_H01_S373_comb


title: CY89COREQ1_B11_S311_comb


title: Cy72_CD45_G06_S750_comb


title: cy80_CD45_pos_PD1_pos_G08_S176_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G06_S270_comb


title: cy53_1_CD45_pos_2_H11_S1055_comb


title: CY88CD45_150813_C05_S317_comb


title: cy53_1_CD45_pos_1_C10_S34_comb


title: CY88CD45POS_2_D07_S427_comb


title: cy60_1_cd_45_pos_HC_pos_HLDAR_pos_D07_S1003_comb


title: CY89A_CD45_POS_6_F08_S164_comb


title: CY58_1_CD45_B11_S983_comb


title: cy79_p5_CD45_pos_PD1_pos_B10_S598_comb


title: cy79_p5_CD45_pos_PD1_pos_E06_S630_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_G01_S457_comb


title: Cy81_FNA_CD45_E05_S245_comb


title: cy58_1_CD45_pos_B09_S597_comb


title: cy94_cd45pos_D02_S134_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D02_S230_comb


title: Cy72_CD45_F03_S735_comb


title: cy60_1_cd_45_pos_4_D11_S47_comb


title: CY75_1FNA_A10_S490_comb


title: Cy81_FNA_CD45_C03_S219_comb


title: CY89A_Core_15_A11_S11_comb


title: cy58_1_CD45_pos_E07_S631_comb


title: cy72_CD45_pos_G02_S938_comb


title: cy94_cd45neg_cd90pos_C04_S316_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_F07_S547_comb


title: cy84_Met_CD45_pos_G01_S937_comb


title: cy58_1_CD45_pos_A05_S581_comb


title: cy94_cd45pos_4_A06_S6_comb


title: cy80_CD45_neg_E10_S442_comb


title: CY89A_CD45_POS_10_B12_S216_comb


title: CY94CD45POS_1_D12_S144_comb


title: cy74_CD45_pos_E11_S731_comb


title: cy84_Primary_CD45_pos_H11_S479_comb


title: Cy74_CD45_G10_S466_comb


title: CY89COREQ1_B12_S312_comb


title: Cy74_CD45_F04_S448_comb


title: cy82_CD45_pos_1_G10_S562_comb


title: CY89A_CD45_POS_6_C06_S126_comb


title: CY89FNA_F05_S257_comb


title: CY58_1_CD45_C02_S986_comb


title: cy74_CD45_pos_F07_S739_comb


title: Cy81_FNA_CD45_F03_S255_comb


title: CY84_PRIM_POS_ALL_6_C09_S417_comb


title: CY89COREQ1_A12_S300_comb


title: cy53_1_CD45_pos_1_E08_S56_comb


title: cy80_Cd45_pos_PD1_pos_S183_H03_S183_comb


title: cy94_cd45pos_4_A04_S4_comb


title: cy88_cd_45_pos_C11_S419_comb


title: CY75_1FNA_H09_S573_comb


title: cy74_CD45_pos_G08_S752_comb


title: cy60_1_cd_45_pos_4_B12_S24_comb


title: CY88CD45POS_2_C07_S415_comb


title: CY94CD45POS_1_H11_S191_comb


title: cy94_cd45pos_4_A01_S1_comb


title: cy79_p4_CD45_pos_PD1_pos_C09_S321_comb


title: cy53_1_CD45_pos_2_D06_S1002_comb


title: cy72_CD45_pos_H05_S953_comb


title: cy80_CD45_pos_PD1_pos_H12_S192_comb


title: CY89A_CD45_POS_6_H08_S188_comb


title: CY89A_CD45_POS_10_G02_S266_comb


title: cy72_CD45_pos_E06_S918_comb


title: cy79_p4_CD45_pos_PD1_pos_H07_S379_comb


title: CY75_1FNA_G11_S563_comb


title: cy53_1_CD45_pos_1_D02_S38_comb


title: CY89A_Core_15_C02_S26_comb


title: CY89A_CD45_POS_6_B06_S114_comb


title: CY89A_Core_15_H07_S91_comb


title: Cy72_CD45_C02_S698_comb


title: cy60_1_cd_45_pos_3_B05_S305_comb


title: Cy74_CD45_E07_S439_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_B06_S498_comb


title: cy58_1_CD45_pos_H06_S666_comb


title: cy82_CD45_pos_3_H10_S94_comb


title: cy58_1_CD45_pos_F08_S644_comb


title: Cy71_CD45_D05_S521_comb


title: CY89FNA_B10_S214_comb


title: cy82_CD45_pos_2_F09_S549_comb


title: cy88_cd_45_pos_F09_S453_comb


title: cy80_CD45_pos_PD1_pos_C06_S126_comb


title: cy88_cd_45_pos_3_D03_S615_comb


title: CY58_1_CD45_H11_S1055_comb


title: cy60_1_cd_45_pos_3_B07_S307_comb


title: cy80_CD45_pos_PD1_pos_C11_S131_comb


title: cy79_p4_CD45_pos_PD1_pos_F12_S360_comb


title: cy80_Cd45_pos_PD1_pos_S160_G04_S160_comb


title: CY89A_CD45_POS_6_E10_S154_comb


title: CY94CD45POS_1_F01_S157_comb


title: cy60_1_cd_45_pos_4_C01_S25_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_G12_S468_comb


title: cy74_CD45_pos_E04_S724_comb


title: cy80_CD45_pos_PD1_pos_B05_S113_comb


title: cy79_p5_CD45_pos_PD1_pos_D01_S613_comb


title: cy88_cd_45_pos_E07_S439_comb


title: cy84_Primary_CD45_pos_E09_S441_comb


title: cy84_Primary_CD45_pos_H10_S478_comb


title: CY89A_Core_15_F01_S61_comb


title: CY58_1_CD45_A03_S963_comb


title: cy80_CD45_neg_D04_S424_comb


title: CY88CD45POS_7_B03_S207_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_A10_S394_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D11_S239_comb


title: CY89COREQ1_C04_S316_comb


title: cy79_p5_CD45_pos_PD1_pos_C05_S605_comb


title: cy80_CD45_pos_PD1_pos_E10_S154_comb


title: cy80_CD45_pos_PD1_pos_B03_S111_comb


title: cy94_cd45pos_4_A09_S9_comb


title: cy60_1_cd_45_pos_4_H03_S87_comb


title: CY89A_CD45_POS_6_C02_S122_comb


title: cy80_Cd45_pos_PD1_pos_B12_S48_comb


title: cy88_cd_45_pos_3_B09_S597_comb


title: CY89A_CD45_POS_6_B10_S118_comb


title: CY89A_Core_15_G10_S82_comb


title: cy88_cd_45_pos_3_C09_S609_comb


title: cy79_p5_CD45_pos_PD1_pos_D06_S618_comb


title: Cy81_FNA_CD45_H02_S278_comb


title: cy84_Primary_CD45_pos_G05_S461_comb


title: cy72_CD45_pos_B10_S886_comb


title: cy53_1_CD45_pos_1_E07_S55_comb


title: Cy72_CD45_D11_S719_comb


title: cy80_Cd45_pos_Pd1_neg_S290_E02_S290_comb


title: CY89COREQ1_D06_S330_comb


title: Cy81_FNA_CD45_B02_S206_comb


title: CY89A_CD45_POS_10_H04_S280_comb


title: cy72_CD45_pos_E09_S921_comb


title: cy80_Cd45_pos_PD1_pos_D09_S93_comb


title: Cy72_CD45_H03_S759_comb


title: Cy74_CD45_D10_S430_comb


title: cy72_CD45_pos_F06_S930_comb


title: cy60_1_cd_45_pos_HC_pos_HLDAR_pos_E10_S1018_comb


title: cy58_1_CD45_pos_D02_S614_comb


title: cy80_CD45_pos_PD1_pos_H09_S189_comb


title: cy80_Cd45_pos_PD1_pos_S184_H04_S184_comb


title: cy79_p5_CD45_pos_PD1_pos_B01_S589_comb


title: CY58_1_CD45_D06_S1002_comb


title: cy79_p4_CD45_pos_PD1_pos_H03_S375_comb


title: Cy81_FNA_CD45_B01_S205_comb


title: cy80_Cd45_pos_PD1_pos_C11_S71_comb


title: Cy72_CD45_E04_S724_comb


title: cy58_1_CD45_pos_F01_S637_comb


title: cy80_Cd45_pos_PD1_pos_B08_S44_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_C01_S217_comb


title: CY75_1FNA_A03_S483_comb


title: cy79_p4_CD45_neg_PDL1_pos_B05_S401_comb


title: cy79_p3_CD45_pos_PD1_neg_C09_S129_comb


title: Cy72_CD45_C12_S708_comb


title: Cy72_CD45_D04_S712_comb


title: cy53_1_CD45_pos_1_C06_S30_comb


title: cy80_CD45_pos_PD1_pos_B09_S117_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_D02_S518_comb


title: cy58_1_CD45_pos_A02_S578_comb


title: cy80_Cd45_pos_PD1_pos_S110_E02_S110_comb


title: cy79_p4_CD45_pos_PD1_pos_G12_S372_comb


title: cy80_CD45_neg_C05_S413_comb


title: Cy74_CD45_C06_S414_comb


title: cy58_1_CD45_pos_E02_S626_comb


title: cy94_cd45pos_G02_S170_comb


title: CY75_1FNA_E12_S540_comb


title: cy58_1_CD45_pos_D01_S613_comb


title: Cy81_FNA_CD45_F10_S262_comb


title: cy53_1_CD45_pos_2_E07_S1015_comb


title: CY88CD45POS_7_E01_S241_comb


title: cy80_CD45_pos_PD1_pos_C12_S132_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_E07_S439_comb


title: CY94CD45POS_1_G07_S175_comb


title: Cy74_CD45_E02_S434_comb


title: cy79_p4_CD45_pos_PD1_pos_F03_S351_comb


title: cy58_1_CD45_pos_C06_S606_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_E08_S440_comb


title: CY89COREQ1_A08_S296_comb


title: Cy74_CD45_B06_S402_comb


title: cy53_1_CD45_pos_1_A11_S11_comb


title: cy53_1_CD45_pos_2_F04_S1024_comb


title: cy60_1_cd_45_pos_4_G07_S79_comb


title: cy79_p5_CD45_pos_PD1_pos_F03_S639_comb


title: cy80_CD45_pos_PD1_pos_F01_S157_comb


title: cy74_CD45_pos_A07_S679_comb


title: Cy81_FNA_CD45_A05_S197_comb


title: Cy74_CD45_H02_S470_comb


title: cy79_p4_CD45_pos_PD1_pos_E01_S337_comb


title: CY94CD45POS_1_C12_S132_comb


title: cy72_CD45_pos_F04_S928_comb


title: Cy72_CD45_F07_S739_comb


title: cy80_CD45_pos_PD1_pos_C05_S125_comb


title: CY58_1_CD45_B08_S980_comb


title: Cy81_FNA_CD45_A08_S200_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_E05_S437_comb


title: cy88_cd_45_pos_3_F09_S645_comb


title: cy60_1_cd_45_pos_HC_pos_HLDAR_pos_E07_S1015_comb


title: cy94_cd45pos_G12_S180_comb


title: CY89FNA_A01_S193_comb


title: cy79_p4_CD45_pos_PD1_pos_G03_S363_comb


title: cy58_1_CD45_pos_B05_S593_comb


title: Cy71_CD45_C08_S512_comb


title: CY88CD45POS_7_F07_S259_comb


title: cy80_Cd45_pos_PD1_pos_S142_F10_S142_comb


title: cy80_CD45_pos_PD1_pos_H07_S187_comb


title: CY75_1FNA_H08_S572_comb


title: Cy74_CD45_G07_S463_comb


title: cy94_cd45pos_4_H04_S88_comb


title: cy94_cd45pos_G08_S176_comb


title: CY89A_Core_15_G11_S83_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_F03_S255_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_H07_S283_comb


title: cy53_1_CD45_pos_2_G01_S1033_comb


title: cy79_p1_CD45_pos_PD1_neg_AS_C1_R2_H10_S574_comb


title: CY94CD45POS_1_F02_S158_comb


title: CY75_1FNA_E11_S539_comb


title: cy58_1_CD45_pos_A10_S586_comb


title: cy74_CD45_pos_E09_S729_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F10_S454_comb


title: cy72_CD45_pos_F09_S933_comb


title: CY88CD45POS_2_C05_S413_comb


title: cy79_p5_CD45_pos_PD1_pos_E01_S625_comb


title: CY88CD45_150813_E11_S347_comb


title: cy60_1_cd_45_pos_4_D07_S43_comb


title: CY88CD45_150813_G09_S369_comb


title: cy60_1_cd_45_pos_4_D06_S42_comb


title: cy60_1_cd_45_pos_HC_pos_HLDAR_pos_H01_S1045_comb


title: cy94_cd45pos_G10_S178_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F03_S447_comb


title: cy94_cd45pos_A01_S97_comb


title: cy80_CD45_neg_H07_S475_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_D08_S236_comb


title: cy53_1_CD45_pos_1_B07_S19_comb


title: cy84_Primary_CD45_pos_B10_S406_comb


title: cy82_CD45_pos_2_B02_S494_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_F05_S257_comb


title: CY58_1_CD45_A04_S964_comb


title: Cy81_FNA_CD45_C02_S218_comb


title: Cy74_CD45_E08_S440_comb


title: Cy72_CD45_F02_S734_comb


title: CY89A_Core_15_F12_S72_comb


title: cy94_cd45pos_D06_S138_comb


title: cy74_CD45_pos_C11_S707_comb


title: cy79_p5_CD45_pos_PD1_pos_E10_S634_comb


title: cy72_CD45_pos_B04_S880_comb


title: Cy74_CD45_G08_S464_comb


title: cy84_Met_CD45_pos_B07_S883_comb


title: cy88_cd45pos_5_G02_S266_comb


title: cy80_CD45_pos_PD1_pos_C01_S121_comb


title: cy82_CD45_pos_2_A12_S492_comb


title: cy80_Cd45_pos_PD1_pos_S144_F12_S144_comb


title: CY89A_CD45_POS_10_A10_S202_comb


title: cy60_1_cd_45_pos_3_E02_S338_comb


title: cy79_p5_CD45_pos_PD1_pos_G08_S656_comb


title: cy80_Cd45_pos_Pd1_neg_S225_B09_S225_comb


title: cy80_CD45_pos_PD1_pos_D02_S134_comb


title: cy74_CD45_pos_F01_S733_comb


title: CY89FNA_G02_S266_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_F09_S261_comb


title: CY58_1_CD45_F03_S1023_comb


title: cy80_CD45_neg_A11_S395_comb


title: CY94CD45POS_1_A02_S98_comb


title: cy53_1_CD45_pos_1_D04_S40_comb


title: cy80_Cd45_pos_PD1_pos_S166_G10_S166_comb


title: cy80_CD45_pos_PD1_pos_F04_S160_comb


title: cy79_p4_CD45_pos_PD1_pos_D06_S330_comb


title: CY89COREQ1_D11_S335_comb


title: cy80_Cd45_pos_Pd1_neg_S226_B10_S226_comb


title: cy79_p5_CD45_pos_PD1_pos_D04_S616_comb


title: cy74_CD45_pos_F03_S735_comb


title: cy84_Met_CD45_pos_B02_S878_comb


title: cy88_cd_45_pos_H06_S474_comb


title: cy82_CD45_pos_1_H09_S573_comb


title: cy53_1_CD45_pos_2_A02_S962_comb


title: Cy72_CD45_B05_S689_comb


title: cy53_1_CD45_pos_1_C09_S33_comb


title: cy74_CD45_pos_G07_S751_comb


title: cy80_Cd45_pos_PD1_pos_A07_S19_comb


title: CY89FNA_D07_S235_comb


title: cy94_cd45pos_4_H09_S93_comb


title: cy53_1_CD45_pos_2_F07_S1027_comb


title: CY88CD45_150813_G05_S365_comb


title: CY89COREQ1_D10_S334_comb


title: CY58_1_CD45_A07_S967_comb


title: Cy74_CD45_G03_S459_comb


title: cy53_1_CD45_pos_1_D10_S46_comb


title: CY88CD45POS_7_G07_S271_comb


title: CY89A_Core_15_G01_S73_comb


title: cy79_p4_CD45_pos_PD1_pos_F02_S350_comb


title: CY89A_CD45_POS_10_G06_S270_comb


title: cy80_CD45_pos_PD1_pos_C03_S123_comb


title: cy53_1_CD45_pos_2_D04_S1000_comb


title: CY89FNA_C08_S224_comb


title: cy80_Cd45_pos_PD1_pos_A06_S18_comb


title: Cy81_FNA_CD45_A07_S199_comb


title: cy78_CD45_neg_2_A06_S582_comb


title: cy80_Cd45_pos_Pd1_neg_S243_C03_S243_comb


title: cy80_Cd45_pos_PD1_pos_D11_S95_comb


title: cy53_1_CD45_pos_2_B05_S977_comb


title: cy94_cd45pos_4_C01_S25_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_C10_S418_comb


title: Cy74_CD45_D03_S423_comb


title: cy60_1_cd_45_pos_3_C03_S315_comb


title: cy53_1_CD45_pos_2_B01_S973_comb


title: cy72_CD45_pos_B02_S878_comb


title: CY88CD45POS_7_G05_S269_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_D02_S422_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_B08_S212_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B03_S399_comb


title: CY89A_CD45_POS_6_D04_S136_comb


title: CY88CD45POS_7_H05_S281_comb


title: CY89FNA_G10_S274_comb


title: Cy72_CD45_F05_S737_comb


title: cy79_p4_CD45_pos_PD1_pos_G02_S362_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_B02_S206_comb


title: cy80_Cd45_pos_Pd1_neg_S337_G01_S337_comb


title: cy60_1_cd_45_pos_3_F08_S356_comb


title: cy60_1_cd_45_pos_3_B06_S306_comb


title: CY89COREQ1_E02_S338_comb


title: CY94CD45POS_1_H02_S182_comb


title: CY58_1_CD45_C03_S987_comb


title: CY89A_Core_15_A01_S1_comb


title: CY89A_Core_15_G07_S79_comb


title: CY88CD45POS_7_F01_S253_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B01_S397_comb


title: Cy74_CD45_G04_S460_comb


title: cy94_cd45pos_4_C11_S35_comb


title: cy88_cd_45_pos_H11_S479_comb


title: cy60_1_cd_45_pos_4_D10_S46_comb


title: cy72_CD45_pos_D08_S908_comb


title: cy84_Primary_CD45_pos_B09_S405_comb


title: CY94CD45POS_1_G04_S172_comb


title: cy72_CD45_pos_C06_S894_comb


title: cy79_p4_CD45_pos_PD1_pos_G05_S365_comb


title: cy84_Primary_CD45_pos_D11_S431_comb


title: cy94_cd45pos_D08_S140_comb


title: cy58_1_CD45_pos_H09_S669_comb


title: Cy81_FNA_CD45_F04_S256_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_E01_S433_comb


title: cy79_p5_CD45_pos_PD1_pos_F02_S638_comb


title: cy74_CD45_pos_A05_S677_comb


title: cy58_1_CD45_pos_F10_S646_comb


title: CY58_1_CD45_G09_S1041_comb


title: cy94_cd45pos_4_A02_S2_comb


title: cy84_Primary_CD45_pos_B07_S403_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_G04_S460_comb


title: cy79_p4_CD45_pos_PD1_pos_F04_S352_comb


title: cy79_p5_CD45_pos_PD1_pos_H06_S666_comb


title: cy53_1_CD45_pos_2_G02_S1034_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_H12_S288_comb


title: CY58_1_CD45_F12_S1032_comb


title: cy94_cd45pos_B11_S119_comb


title: Cy71_CD45_C01_S505_comb


title: cy80_Cd45_pos_PD1_pos_S190_H10_S190_comb


title: CY58_1_CD45_E05_S1013_comb


title: cy74_CD45_pos_E03_S723_comb


title: cy80_CD45_neg_F04_S448_comb


title: cy79_p5_CD45_pos_PD1_pos_B08_S596_comb


title: CY89COREQ1_D01_S325_comb


title: cy80_Cd45_pos_Pd1_neg_S364_H04_S364_comb


title: cy60_1_cd_45_pos_3_H12_S384_comb


title: cy79_p5_CD45_pos_PD1_pos_E04_S628_comb


title: CY94CD45POS_1_A09_S105_comb


title: cy79_p5_CD45_pos_PD1_pos_G12_S660_comb


title: cy72_CD45_pos_E04_S916_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B12_S408_comb


title: CY89COREQ1_D03_S327_comb


title: CY58_1_CD45_F09_S1029_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_B09_S213_comb


title: cy60_1_cd_45_pos_4_B11_S23_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F12_S456_comb


title: Cy72_CD45_E10_S730_comb


title: CY88CD45POS_2_D11_S431_comb


title: CY58_1_CD45_F04_S1024_comb


title: CY89COREQ1_C03_S315_comb


title: cy80_Cd45_pos_Pd1_neg_S265_D01_S265_comb


title: cy72_CD45_pos_A05_S869_comb


title: Cy81_FNA_CD45_C11_S227_comb


title: cy94_cd45pos_D05_S137_comb


title: CY89FNA_A02_S194_comb


title: CY94CD45POS_1_H01_S181_comb


title: cy60_1_cd_45_pos_3_C07_S319_comb


title: cy58_1_CD45_pos_E08_S632_comb


title: cy94_cd45neg_cd90pos_C03_S315_comb


title: CY89COREQ1_B04_S304_comb


title: cy79_p4_CD45_pos_PD1_pos_C10_S322_comb


title: CY58_1_CD45_G11_S1043_comb


title: CY58_1_CD45_D04_S1000_comb


title: cy80_Cd45_pos_PD1_pos_B07_S43_comb


title: cy80_CD45_neg_C12_S420_comb


title: CY89A_Core_15_B05_S17_comb


title: Cy72_CD45_A11_S683_comb


title: cy84_Primary_CD45_pos_D10_S430_comb


title: cy79_p4_CD45_pos_PD1_pos_F01_S349_comb


title: Cy72_CD45_G01_S745_comb


title: CY89A_CD45_POS_6_D10_S142_comb


title: cy88_cd_45_pos_H07_S475_comb


title: cy53_1_CD45_pos_2_H08_S1052_comb


title: Cy71_CD45_F03_S543_comb


title: cy88_cd_45_pos_F07_S451_comb


title: CY94CD45POS_1_B09_S117_comb


title: cy80_CD45_neg_H03_S471_comb


title: CY89A_Core_15_H12_S96_comb


title: cy80_CD45_neg_A12_S396_comb


title: cy80_CD45_neg_G01_S457_comb


title: CY75_1FNA_F01_S541_comb


title: cy79_p4_CD45_pos_PD1_pos_E07_S343_comb


title: cy82_CD45_pos_1_F08_S548_comb


title: cy80_Cd45_pos_PD1_pos_S140_F08_S140_comb


title: cy60_1_cd_45_pos_3_H04_S376_comb


title: cy79_p5_CD45_pos_PD1_pos_C07_S607_comb


title: Cy74_CD45_H12_S480_comb


title: cy84_Primary_CD45_pos_E04_S436_comb


title: cy74_CD45_pos_C07_S703_comb


title: cy72_CD45_pos_D07_S907_comb


title: CY84_PRIM_POS_ALL_7_B11_S215_comb


title: CY88CD45POS_2_D03_S423_comb


title: Cy72_CD45_H06_S762_comb


title: cy58_1_CD45_pos_H08_S668_comb


title: Cy74_CD45_H06_S474_comb


title: cy88_cd_45_pos_H10_S478_comb


title: CY89A_Core_15_C08_S32_comb


title: CY88CD45_150813_G07_S367_comb


title: CY89A_Core_15_C09_S33_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_F10_S262_comb


title: cy80_Cd45_pos_PD1_pos_B01_S37_comb


title: cy80_CD45_neg_E04_S436_comb


title: cy88_cd45pos_5_C03_S219_comb


title: cy58_1_CD45_pos_C11_S611_comb


title: cy94_cd45pos_A10_S106_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_A10_S202_comb


title: cy60_1_cd_45_pos_4_E02_S50_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_C07_S223_comb


title: cy74_CD45_pos_C03_S699_comb


title: cy60_1_cd_45_pos_4_C10_S34_comb


title: cy58_1_CD45_pos_G04_S652_comb


title: cy72_CD45_pos_D10_S910_comb


title: cy82_CD45_pos_2_A05_S485_comb


title: cy58_1_CD45_pos_D03_S615_comb


title: cy79_p1_CD45_pos_PD1_pos_AS_C5_R1_G11_S275_comb


title: cy60_1_cd_45_pos_3_G04_S364_comb


title: cy80_Cd45_pos_PD1_pos_S135_F03_S135_comb


title: CY89A_CD45_POS_6_D02_S134_comb


title: cy60_1_cd_45_pos_4_E09_S57_comb


title: cy58_1_CD45_pos_G09_S657_comb


title: cy79_p5_CD45_pos_PD1_pos_D03_S615_comb


title: cy72_CD45_pos_C07_S895_comb


title: CY94CD45POS_1_E12_S156_comb


title: Cy81_FNA_CD45_B08_S212_comb


title: cy74_CD45_pos_G11_S755_comb


title: cy79_p3_CD45_pos_PD1_neg_F09_S165_comb


title: cy88_cd_45_pos_E01_S433_comb


title: cy88_cd_45_pos_C07_S415_comb


title: Cy71_CD45_D12_S528_comb


title: cy88_cd_45_pos_G02_S458_comb


title: cy79_p5_CD45_pos_PD1_pos_H07_S667_comb


title: Cy74_CD45_F08_S452_comb


title: CY89A_CD45_POS_6_G03_S171_comb


title: CY89A_CD45_POS_6_B02_S110_comb


title: Cy72_CD45_D01_S709_comb


title: CY88CD45_150813_G02_S362_comb


title: CY89A_CD45_POS_6_B08_S116_comb


title: cy58_1_CD45_pos_B07_S595_comb


title: cy79_p5_CD45_pos_PD1_pos_G05_S653_comb


title: Cy74_CD45_G01_S457_comb


title: cy88_cd_45_pos_C09_S417_comb


title: cy80_Cd45_pos_Pd1_neg_S340_G04_S340_comb


title: cy80_Cd45_pos_PD1_pos_A09_S21_comb


title: cy80_CD45_pos_PD1_pos_H03_S183_comb


title: cy80_Cd45_pos_PD1_pos_S137_F05_S137_comb


title: cy84_Primary_CD45_pos_B11_S407_comb


title: cy79_p4_CD45_pos_PD1_pos_E09_S345_comb


title: Cy74_CD45_F02_S446_comb


title: cy60_1_cd_45_pos_3_A02_S290_comb


title: CY88CD45_150813_E03_S339_comb


title: cy58_1_CD45_pos_C09_S609_comb


title: cy80_Cd45_pos_Pd1_neg_S224_B08_S224_comb


title: Cy74_CD45_B03_S399_comb


title: CY88CD45_150813_E06_S342_comb


title: cy84_Primary_CD45_pos_H02_S470_comb


title: CY88CD45POS_7_D05_S233_comb


title: CY89A_Core_15_G06_S78_comb


title: cy94_cd45pos_4_H02_S86_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_F09_S453_comb


title: cy88_cd45pos_5_F05_S257_comb


title: cy53_1_CD45_neg_D02_S326_comb


title: CY88CD45_150813_E01_S337_comb


title: cy53_1_CD45_pos_2_G05_S1037_comb


title: cy58_1_CD45_pos_F03_S639_comb


title: cy74_CD45_pos_E02_S722_comb


title: Cy81_FNA_CD45_D11_S335_comb

value: Mal


title: CY94CD45POS_1_D09_S141_comb


title: cy79_p3_CD45_neg_PDL1_neg_E12_S252_comb


title: cy88_cd_45_pos_B07_S403_comb


title: CY89A_CD45_POS_10_H07_S283_comb


title: cy80_CD45_neg_C11_S899_comb


title: Cy71_CD45_C04_S508_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_E02_S338_comb


title: cy78_CD45_neg_1_F11_S551_comb


title: cy79_p4_CD45_neg_PDL1_pos_A05_S389_comb


title: cy78_CD45_neg_1_A06_S486_comb


title: Cy71_CD45_F08_S548_comb


title: cy79_p3_CD45_neg_PDL1_neg_D05_S233_comb


title: cy78_CD45_neg_3_A09_S681_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_C09_S33_comb


title: cy80_CD45_pos_PD1_pos_A06_S102_comb


title: cy79_p3_CD45_neg_PDL1_neg_D07_S235_comb


title: cy53_1_CD45_neg_F08_S356_comb


title: Cy71_CD45_C02_S506_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_H06_S186_comb


title: cy79_p5_CD45_neg_PDL1_neg_H08_S860_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_H12_S192_comb


title: Cy81_Bulk_CD45_D06_S138_comb

value: Undetermined


title: cy53_1_CD45_neg_C09_S321_comb


title: cy78_CD45_neg_3_F10_S742_comb


title: Cy71_CD45_C10_S514_comb


title: cy79_p5_CD45_neg_PDL1_pos_G08_S752_comb


title: CY88_3_F08_S644_comb


title: cy79_p4_CD45_neg_PDL1_pos_B09_S405_comb


title: cy79_p5_CD45_neg_PDL1_pos_B11_S695_comb


title: cy78_CD45_neg_2_A10_S586_comb


title: cy79_p3_CD45_neg_PDL1_neg_F02_S254_comb


title: Cy81_Bulk_CD45_A02_S98_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_A03_S3_comb


title: cy79_p4_CD45_neg_PDL1_neg_H02_S1142_comb


title: cy79_p4_CD45_neg_PDL1_pos_E07_S439_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_A08_S8_comb


title: Cy81_Bulk_CD45_E06_S150_comb


title: cy79_p3_CD45_neg_PDL1_neg_H11_S287_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_E06_S342_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_E06_S54_comb


title: cy79_p5_CD45_neg_PDL1_pos_D10_S718_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_A03_S291_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C11_S131_comb


title: cy79_p4_CD45_neg_PDL1_neg_F04_S1120_comb


title: cy78_CD45_neg_1_B12_S504_comb


title: CY88_3_E08_S632_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_A09_S105_comb


title: Cy81_Bulk_CD45_A12_S108_comb


title: Cy71_CD45_C07_S511_comb


title: Cy80_II_CD45_A06_S870_comb


title: cy84_Primary_CD45_neg_H02_S1046_comb


title: cy81_FNA_CD45_neg_H11_S1055_comb


title: CY88_3_A05_S581_comb


title: Cy81_FNA_CD45_H01_S373_comb


title: cy79_p5_CD45_neg_PDL1_neg_D08_S812_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_H06_S378_comb


title: cy79_p5_CD45_neg_PDL1_pos_F03_S735_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_C10_S322_comb


title: cy79_p4_CD45_neg_PDL1_neg_H07_S1147_comb


title: CY88_5_A09_S681_comb


title: cy79_p5_CD45_neg_PDL1_pos_B12_S696_comb


title: cy81_FNA_CD45_neg_H10_S1054_comb


title: cy78_CD45_neg_3_G03_S747_comb


title: CY88_5_A07_S679_comb


title: CY88_3_D05_S617_comb


title: cy79_p3_CD45_neg_PDL1_neg_D08_S236_comb


title: Cy80_II_CD45_H12_S960_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_D07_S43_comb


title: cy78_CD45_neg_3_B05_S689_comb


title: Cy81_FNA_CD45_B04_S304_comb


title: cy79_p3_CD45_neg_PDL1_neg_H07_S283_comb

value: Endo.


title: cy79_p5_CD45_neg_PDL1_pos_B08_S692_comb


title: CY88_3_F06_S642_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_E12_S348_comb


title: cy78_CD45_neg_3_D11_S719_comb


title: Cy81_Bulk_CD45_D08_S140_comb


title: cy79_p4_CD45_neg_PDL1_pos_G02_S458_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_D11_S47_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_G01_S169_comb


title: cy78_CD45_neg_3_G08_S752_comb


title: cy78_CD45_neg_1_C05_S509_comb


title: cy81_FNA_CD45_neg_E10_S1018_comb


title: CY88_5_B02_S686_comb


title: Cy81_Bulk_CD45_F05_S161_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_C08_S320_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_F09_S357_comb


title: cy53_1_CD45_neg_F07_S355_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_B06_S18_comb


title: cy78_CD45_neg_3_B10_S694_comb


title: CY88_3_H04_S664_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_G10_S370_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_B06_S114_comb


title: cy81_Bulk_CD45_neg_H02_S182_comb


title: cy79_p5_CD45_neg_PDL1_neg_E04_S820_comb


title: cy60_1_cd_45_neg_1_C08_S224_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G12_S84_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_D10_S142_comb


title: cy81_FNA_CD45_neg_B03_S975_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_D08_S140_comb


title: cy81_FNA_CD45_neg_H02_S1046_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_F12_S168_comb


title: cy79_p5_CD45_neg_PDL1_pos_D07_S715_comb


title: cy79_p5_CD45_neg_PDL1_pos_C02_S698_comb


title: cy79_p4_CD45_neg_PDL1_neg_A02_S1058_comb


title: cy81_FNA_CD45_neg_F01_S1021_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C03_S123_comb


title: cy94_cd45neg_cd90pos_D02_S326_comb


title: cy79_p4_CD45_neg_PDL1_pos_F10_S454_comb


title: cy81_FNA_CD45_neg_E01_S1009_comb


title: cy79_p3_CD45_pos_PD1_pos_AS_C2_R1_B08_S404_comb


title: cy80_CD45_neg_A10_S874_comb


title: CY88_3_G10_S658_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_C09_S321_comb


title: Cy71_CD45_A07_S487_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_F08_S164_comb


title: cy78_CD45_neg_2_B05_S593_comb


title: cy79_p4_CD45_neg_PDL1_neg_A10_S1066_comb


title: cy82_CD45_pos_2_D03_S519_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_H04_S184_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_B01_S109_comb


title: cy79_p4_CD45_neg_PDL1_pos_G10_S466_comb


title: cy94_cd45neg_cd90pos_D01_S325_comb


title: cy78_CD45_neg_3_A11_S683_comb


title: CY88_3_D11_S623_comb


title: cy79_p5_CD45_neg_PDL1_pos_E01_S721_comb


title: cy79_p5_CD45_neg_PDL1_pos_G06_S750_comb


title: cy81_Bulk_CD45_neg_A07_S103_comb


title: CY88_5_A12_S684_comb


title: cy81_FNA_CD45_neg_E08_S1016_comb


title: cy81_Bulk_CD45_neg_H07_S187_comb


title: cy79_p5_CD45_neg_PDL1_pos_C05_S701_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_G03_S363_comb


title: Cy71_CD45_G11_S563_comb


title: Cy81_FNA_CD45_D12_S336_comb


title: cy79_p4_CD45_neg_PDL1_neg_G02_S1130_comb


title: cy82_CD45_pos_3_A08_S8_comb


title: cy79_p4_CD45_neg_PDL1_neg_B12_S1080_comb


title: cy79_p5_CD45_neg_PDL1_neg_A08_S776_comb


title: Cy81_FNA_CD45_H05_S377_comb


title: cy81_FNA_CD45_neg_D12_S1008_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_F08_S356_comb


title: cy82_CD45_pos_1_H12_S576_comb

value: Macrophage


title: Cy80_II_CD45_E08_S920_comb


title: cy79_p5_CD45_neg_PDL1_neg_B07_S787_comb


title: cy79_p5_CD45_neg_PDL1_neg_D02_S806_comb


title: CY88_3_F09_S645_comb


title: CY88_5_F06_S738_comb


title: CY88_5_H06_S762_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_B12_S312_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_G11_S371_comb


title: cy78_CD45_neg_3_H04_S760_comb


title: cy82_CD45_pos_3_H12_S96_comb


title: cy81_Bulk_CD45_neg_B04_S112_comb


title: cy79_p5_CD45_neg_PDL1_neg_H11_S863_comb


title: cy80_CD45_pos_PD1_pos_D09_S141_comb


title: Cy71_CD45_H12_S576_comb


title: cy79_p4_CD45_neg_PDL1_pos_G09_S465_comb


title: cy78_CD45_neg_3_G10_S754_comb


title: cy80_CD45_neg_A06_S870_comb


title: cy79_p3_CD45_neg_PDL1_neg_C01_S217_comb


title: Cy81_Bulk_CD45_A08_S104_comb


title: cy79_p4_CD45_neg_PDL1_pos_F01_S445_comb


title: cy79_p4_CD45_neg_PDL1_pos_B12_S408_comb


title: cy78_CD45_neg_1_D04_S520_comb


title: cy81_Bulk_CD45_neg_B02_S110_comb


title: CY88_5_A03_S675_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_G07_S175_comb


title: cy84_Primary_CD45_neg_A10_S970_comb


title: Cy71_CD45_E05_S533_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_D03_S327_comb


title: cy82_CD45_pos_3_A12_S12_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G02_S74_comb


title: cy79_p4_CD45_neg_PDL1_neg_D08_S1100_comb


title: cy82_CD45_pos_2_D12_S528_comb


title: Cy71_CD45_C09_S513_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_C12_S324_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_A08_S104_comb


title: CY88_5_F03_S735_comb


title: cy79_p4_CD45_neg_PDL1_pos_F04_S448_comb


title: cy79_p5_CD45_neg_PDL1_neg_G08_S848_comb


title: Cy71_CD45_A06_S486_comb


title: cy81_Bulk_CD45_neg_D01_S133_comb


title: cy78_CD45_neg_1_C06_S510_comb


title: CY88_3_G01_S649_comb


title: CY89NEG_E03_S51_comb


title: cy79_p3_CD45_neg_PDL1_neg_H01_S277_comb


title: CY88_5_H04_S760_comb


title: cy82_CD45_pos_2_F02_S542_comb


title: CY84_PRIM_POS_ALL_6_G01_S457_comb


title: cy79_p4_CD45_neg_PDL1_neg_E09_S1113_comb


title: cy79_p4_CD45_neg_PDL1_neg_H05_S1145_comb


title: Cy71_CD45_C12_S516_comb


title: CY88_3_F10_S646_comb


title: CY88_3_A11_S587_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C09_S129_comb


title: cy79_p4_CD45_neg_PDL1_pos_A06_S390_comb


title: cy79_p3_CD45_neg_PDL1_neg_H05_S281_comb


title: cy80_CD45_neg_B03_S879_comb


title: cy78_CD45_neg_3_C04_S700_comb


title: cy79_p4_CD45_neg_PDL1_pos_B07_S403_comb


title: CY84_PRIM_POS_ALL_6_D06_S426_comb


title: cy81_FNA_CD45_neg_C11_S995_comb


title: CY89NEG_C10_S34_comb


title: Cy80_II_CD45_E11_S923_comb


title: cy81_FNA_CD45_neg_D03_S999_comb


title: cy81_FNA_CD45_neg_E06_S1014_comb


title: cy79_p3_CD45_neg_PDL1_neg_C03_S219_comb


title: cy79_p5_CD45_neg_PDL1_neg_A09_S777_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C06_S126_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_E03_S339_comb


title: cy79_p5_CD45_neg_PDL1_pos_H09_S765_comb


title: CY88_3_A08_S584_comb


title: cy79_p4_CD45_neg_PDL1_neg_C08_S1088_comb


title: cy81_FNA_CD45_neg_D01_S997_comb


title: cy81_Bulk_CD45_neg_H12_S192_comb


title: CY88_3_G12_S660_comb


title: Cy71_CD45_E06_S534_comb


title: cy79_p4_CD45_neg_PDL1_pos_C06_S414_comb


title: CY88_3_C06_S606_comb


title: cy79_p3_CD45_neg_PDL1_neg_G12_S276_comb


title: Cy80_II_CD45_A01_S865_comb


title: Cy81_Bulk_CD45_F12_S168_comb


title: CY88_5_A06_S678_comb


title: CY89NEG_A12_S12_comb


title: cy80_CD45_neg_E05_S917_comb


title: CY88_3_E07_S631_comb


title: CY88_3_F11_S647_comb


title: CY89NEG_A10_S10_comb


title: Cy81_FNA_CD45_H09_S381_comb


title: cy79_p4_CD45_neg_PDL1_pos_H05_S473_comb


title: cy82_CD45_neg_3_A11_S779_comb


title: cy82_CD45_pos_1_D01_S517_comb


title: cy79_p4_CD45_neg_PDL1_pos_D09_S429_comb


title: cy78_CD45_neg_3_E06_S726_comb


title: cy79_p5_CD45_neg_PDL1_pos_C04_S700_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_B03_S111_comb


title: Cy80_II_CD45_H11_S959_comb


title: cy78_CD45_neg_1_H05_S569_comb


title: cy82_CD45_pos_1_B11_S503_comb


title: CY88_3_G05_S653_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_G09_S177_comb


title: cy81_FNA_CD45_neg_E09_S1017_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_A02_S98_comb


title: Cy81_FNA_CD45_F07_S355_comb


title: Cy81_FNA_CD45_E04_S340_comb


title: CY89FNAQ2_G04_S460_comb


title: cy80_CD45_neg_F08_S932_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_D02_S326_comb


title: cy80_CD45_neg_B08_S884_comb


title: cy79_p5_CD45_neg_PDL1_pos_D09_S717_comb


title: cy78_CD45_neg_2_A05_S581_comb


title: cy78_CD45_neg_1_C01_S505_comb


title: cy79_p3_CD45_neg_PDL1_neg_F03_S255_comb


title: cy79_p4_CD45_neg_PDL1_pos_B03_S399_comb


title: CY89CORE11_F10_S166_comb


title: cy79_p4_CD45_neg_PDL1_pos_G04_S460_comb


title: cy81_Bulk_CD45_neg_G06_S174_comb


title: cy79_p3_CD45_neg_PDL1_neg_B07_S211_comb


title: CY88_5_G02_S746_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C04_S124_comb


title: cy80_CD45_neg_D02_S902_comb


title: cy80_CD45_neg_F01_S925_comb


title: cy79_p5_CD45_neg_PDL1_pos_F10_S742_comb


title: CY88_3_A12_S588_comb


title: cy60_1_cd_45_neg_1_D11_S239_comb


title: cy78_CD45_neg_2_C07_S607_comb


title: CY88_3_E02_S626_comb


title: Cy80_II_CD45_E01_S913_comb


title: CY89NEG_G08_S80_comb


title: cy53_1_CD45_neg_A12_S300_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_B05_S113_comb


title: CY88_3_B09_S597_comb


title: cy79_p4_CD45_neg_PDL1_neg_G12_S1140_comb


title: Cy80_II_CD45_F01_S925_comb


title: CY88_5_C01_S697_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_F02_S62_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_A06_S6_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C12_S132_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_F10_S70_comb


title: cy82_CD45_pos_2_G05_S557_comb


title: cy82_CD45_pos_2_E02_S530_comb


title: cy79_p5_CD45_neg_PDL1_neg_C04_S796_comb


title: Cy81_FNA_CD45_B02_S302_comb


title: cy79_p5_CD45_neg_PDL1_neg_D05_S809_comb


title: CY89FNAQ2_D06_S426_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_E02_S50_comb


title: CY89CORE11_E12_S156_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_G01_S361_comb


title: CY88_5_A05_S677_comb


title: Cy80_II_CD45_C02_S890_comb


title: cy78_CD45_neg_1_A11_S491_comb


title: cy79_p5_CD45_neg_PDL1_pos_B09_S693_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_G06_S366_comb


title: pre-therapeutic LARC biopsy_35B

type: RNA

city: Belfast

first: Matthew

last: Alderdice

address: 97 Lisburn Road

department: Centre for Cancer Research and Cell Biology

country: United Kingdom

institute: Queen's University Belfast

description: Tumour

hyb_protocol: Fluorescent cDNA was hybridized on HumanHT-12_V4 beadchip for 16 hours. Arrays washed with wash buffer

scan_protocol: Hybridized Beadchips were scanned using Illumina HiScan.

data_processing: The data were normalised using quantile normalisation and log2 transformed with the Partek reporter plug-in

label: biotin

source_name: pre-therapeutic LARC biopsy

label_protocol: Fluorescent cDNA were obtained using the Human Whole-Genome DASL HT Assay kit Illumina

extract_protocol: RNA was extracted using the QIAGEN RNAeasy kit as to manufacturer's protocol. Quantification and QC was performed by Nanodrop

tag: tissue

value: Locally Advanced Rectal Cancer (LARC)

tag: tissue type

value: Biopsy

tag: tumour regression grade


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G11_S83_comb


title: CY89CORE11_B08_S116_comb


title: post-therapeutic LARC resection_39R

description: Tumour

source_name: post-therapeutic LARC resection

value: Resection


title: post-therapeutic LARC resection_51R

description: Tumour


title: cy80_CD45_neg_C03_S891_comb


title: post-therapeutic LARC resection_48R

description: Tumour


title: post-therapeutic LARC resection_1R

description: Tumour


title: post-therapeutic LARC resection_42R

description: Tumour


title: CY88_3_H08_S668_comb


title: post-therapeutic LARC resection_35R

description: Tumour


title: post-therapeutic LARC resection_36R

description: Tumour


title: Cy71_CD45_F07_S547_comb


title: pre-therapeutic LARC biopsy_1B

description: Tumour


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G05_S77_comb


title: post-therapeutic LARC resection_55R

description: Tumour


title: Cy81_Bulk_CD45_B05_S113_comb


title: CY89FNAQ2_C06_S414_comb


title: post-therapeutic LARC resection_40R

description: Tumour


title: pre-therapeutic LARC biopsy_48B

description: Tumour


title: pre-therapeutic LARC biopsy_39B

description: Tumour


title: post-therapeutic LARC resection_50R

description: Tumour


title: cy79_p4_CD45_neg_PDL1_neg_G06_S1134_comb


title: pre-therapeutic LARC biopsy_42B

description: Tumour


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_A11_S11_comb


title: post-therapeutic LARC resection_37R

description: Tumour


title: CY89NEG_B01_S13_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_E05_S53_comb


title: CY88_3_G03_S651_comb


title: pre-therapeutic LARC biopsy_37B

description: Tumour


title: pre-therapeutic LARC biopsy_50B

description: Tumour


title: pre-therapeutic LARC biopsy_55B

description: Tumour


title: pre-therapeutic LARC biopsy_36B

description: Tumour


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_E01_S145_comb


title: cy79_p4_CD45_neg_PDL1_neg_A11_S1067_comb


title: pre-therapeutic LARC biopsy_40B

description: Tumour


title: cy60_1_cd_45_neg_3_F09_S549_comb


title: CY89FNAQ2_G05_S461_comb


title: cy79_p5_CD45_neg_PDL1_pos_F05_S737_comb


title: pre-therapeutic LARC biopsy_58B

description: Tumour


title: cy79_p4_CD45_neg_PDL1_pos_B06_S402_comb


title: pre-therapeutic LARC biopsy_51B

description: Tumour


title: post-therapeutic LARC resection_56R

description: Tumour


title: post-therapeutic LARC resection_57R

description: Tumour


title: cy79_p3_CD45_neg_PDL1_neg_H02_S278_comb


title: post-therapeutic LARC resection_59R

description: Tumour


title: CY88_3_B08_S596_comb


title: pre-therapeutic LARC biopsy_57B

description: Tumour


title: pre-therapeutic LARC biopsy_59B

description: Tumour


title: cy78_CD45_neg_3_H02_S758_comb


title: cy78_CD45_neg_3_F09_S741_comb


title: post-therapeutic LARC resection_41R

description: Tumour


title: post-therapeutic LARC resection_46R

description: Tumour


title: cy79_p3_CD45_neg_PDL1_neg_B09_S213_comb


title: Cy81_FNA_CD45_F03_S351_comb


title: cy79_p5_CD45_neg_PDL1_pos_G04_S748_comb


title: pre-therapeutic LARC biopsy_46B

description: Tumour


title: pre-therapeutic LARC biopsy_56B

description: Tumour


title: cy81_Bulk_CD45_neg_G07_S175_comb


title: cy84_Primary_CD45_neg_E05_S1013_comb


title: cy79_p3_CD45_neg_PDL1_neg_C02_S218_comb


title: pre-therapeutic LARC biopsy_41B

description: Tumour


title: cy79_p3_CD45_neg_PDL1_neg_C09_S225_comb


title: post-therapeutic LARC resection_58R

description: Tumour


title: cy78_CD45_neg_1_G12_S564_comb


title: post-therapeutic LARC resection_44R

description: Tumour


title: pre-therapeutic LARC biopsy_44B

description: Tumour


title: post-therapeutic LARC resection_53R

description: Tumour


title: cy78_CD45_neg_3_E07_S727_comb


title: cy79_p5_CD45_neg_PDL1_pos_G07_S751_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C05_S125_comb


title: post-therapeutic LARC resection_38R

description: Tumour


title: pre-therapeutic LARC biopsy_53B

description: Tumour


title: cy79_p4_CD45_neg_PDL1_neg_F09_S1125_comb


title: pre-therapeutic LARC biopsy_45B

description: Tumour


title: CY89NEG_A07_S7_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_F03_S351_comb


title: cy79_p3_CD45_neg_PDL1_neg_C10_S226_comb


title: cy79_p4_CD45_neg_PDL1_neg_D11_S1103_comb


title: Cy71_CD45_G05_S557_comb


title: pre-therapeutic LARC biopsy_38B

description: Tumour


title: pre-therapeutic LARC biopsy_32B

description: Tumour


title: post-therapeutic LARC resection_32R

description: Tumour


title: post-therapeutic LARC resection_45R

description: Tumour


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_D08_S332_comb


title: pre-therapeutic LARC biopsy_2B

description: Tumour


title: CY89CORE11_A03_S99_comb


title: cy78_CD45_neg_1_H03_S567_comb


title: pre-therapeutic LARC biopsy_22B

description: Tumour


title: cy79_p5_CD45_neg_PDL1_neg_F08_S836_comb


title: post-therapeutic LARC resection_20R

description: Tumour


title: pre-therapeutic LARC biopsy_25B

description: Tumour


title: post-therapeutic LARC resection_25R

description: Tumour


title: post-therapeutic LARC resection_26R

description: Tumour


title: pre-therapeutic LARC biopsy_20B

description: Tumour


title: cy79_p3_CD45_neg_PDL1_neg_E01_S241_comb


title: Cy81_Bulk_CD45_B04_S112_comb


title: CY88_3_A02_S578_comb


title: CY89CORE11_D05_S137_comb


title: cy78_CD45_neg_1_B06_S498_comb


title: pre-therapeutic LARC biopsy_26B

description: Tumour


title: post-therapeutic LARC resection_2R

description: Tumour


title: post-therapeutic LARC resection_22R

description: Tumour


title: pre-therapeutic LARC biopsy_27B

description: Tumour


title: post-therapeutic LARC resection_27R

description: Tumour


title: CY89NEG_F08_S68_comb


title: cy79_p5_CD45_neg_PDL1_neg_D10_S814_comb


title: cy79_p4_CD45_neg_PDL1_neg_C09_S1089_comb


title: cy79_p4_CD45_neg_PDL1_neg_F07_S1123_comb


title: post-therapeutic LARC resection_24R

description: Tumour


title: cy81_Bulk_CD45_neg_G04_S172_comb


title: cy78_CD45_neg_2_B10_S598_comb


title: cy79_p4_CD45_neg_PDL1_neg_G03_S1131_comb


title: pre-therapeutic LARC biopsy_24B

description: Tumour


title: post-therapeutic LARC resection_6R

description: Tumour


title: post-therapeutic LARC resection_21R

description: Tumour


title: Cy71_CD45_F01_S541_comb


title: CY88_5_C02_S698_comb


title: pre-therapeutic LARC biopsy_21B

description: Tumour


title: cy79_p4_CD45_neg_PDL1_pos_C11_S419_comb


title: CY88_3_A07_S583_comb


title: pre-therapeutic LARC biopsy_8B

description: Tumour


title: post-therapeutic LARC resection_18R

description: Tumour


title: cy78_CD45_neg_1_B11_S503_comb


title: cy79_p4_CD45_neg_PDL1_neg_H04_S1144_comb


title: post-therapeutic LARC resection_8R

description: Tumour


title: pre-therapeutic LARC biopsy_6B

description: Tumour


title: cy79_p4_CD45_neg_PDL1_neg_C02_S1082_comb


title: cy80_CD45_neg_E10_S922_comb


title: pre-therapeutic LARC biopsy_17B

description: Tumour


title: cy78_CD45_neg_3_B01_S685_comb


title: pre-therapeutic LARC biopsy_18B

description: Tumour


title: post-therapeutic LARC resection_17R

description: Tumour


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_B04_S16_comb


title: cy78_CD45_neg_1_D01_S517_comb


title: post-therapeutic LARC resection_15R

description: Tumour


title: cy80_CD45_neg_C02_S890_comb


title: CY88_3_D09_S621_comb


title: cy80_CD45_neg_D01_S901_comb


title: cy79_p4_CD45_neg_PDL1_pos_A12_S396_comb


title: cy79_p5_CD45_neg_PDL1_pos_H10_S766_comb


title: post-therapeutic LARC resection_13R

description: Tumour


title: pre-therapeutic LARC biopsy_15B

description: Tumour


title: pre-therapeutic LARC biopsy_7B

description: Tumour


title: cy79_p5_CD45_neg_PDL1_pos_G03_S747_comb


title: pre-therapeutic LARC biopsy_10B

description: Tumour


title: post-therapeutic LARC resection_7R

description: Tumour


title: pre-therapeutic LARC biopsy_3B

description: Tumour


title: post-therapeutic LARC resection_10R

description: Tumour


title: CY88_3_D03_S615_comb


title: pre-therapeutic LARC biopsy_13B

description: Tumour


title: post-therapeutic LARC resection_9R

description: Tumour


title: CY89NEG_D05_S41_comb


title: Cy81_FNA_CD45_C08_S320_comb


title: pre-therapeutic LARC biopsy_9B

description: Tumour


title: Cy81_Bulk_CD45_C05_S125_comb


title: post-therapeutic LARC resection_3R

description: Tumour


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_E11_S347_comb


title: Cy71_CD45_E02_S530_comb


title: CY89NEG_F04_S64_comb


title: cy78_CD45_neg_2_A12_S588_comb


title: EMca_NORMAL_47

city: Sendai

first: ERI

last: HIROKI

address: 1-1 Seiryo-Machi, Aoba-ku

department: Obstetrics and Gynecology

country: Japan

institute: Tohoku University

description: normal endometrial tissues_47

hyb_protocol: 1.5 ug of Cy3-labelled cRNA (specific activity >10.0 pmol Cy3/ug cRNA) was fragmented at 60°C for 30 minutes in a reaction volume of 250 ml containing 1x Agilent fragmentation buffer and 2x Agilent blocking agent following the manufacturers instructions. On completion of the fragmentation reaction, 250 ml of 2x Agilent hybridization buffer was added to the fragmentation mixture and hybridized to Agilent human miRNA V2 Oligo Microarray Kit (G4470B) for 17 hours at 65°C in a rotating Agilent hybridization oven. After hybridization, microarrays were washed 1 minute at room temperature with GE Wash Buffer 1 (Agilent) and 1 minute with 37°C GE Wash buffer 2 (Agilent), then dried immediately by brief centrifugation.

scan_protocol: The arrays were scanned with an Agilent microarray scanner (Agilent Technologies) using high dynamic range settings as specified by the manufacturer.

data_processing: Microarray results were extracted using Agilent Feature Extraction software Ver. 9.5.3.1 (Agilent Technologies) and analyzed using Gene Spring GX 7.3.1 software (Agilent Technologies) to obtain gene expression ratios. Ratio of intensities values above or less than 2.0 were considered significant for upregulated or downregulated genes.

label_protocol: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the One-Color Low RNA Input Linear Amplification PLUS kit (Agilent) according to the manufacturer's instructions, followed by miRNAeasy column purification (QIAGEN, Valencia, CA). Dye incorporation and cRNA yield were checked with the NanoDrop ND-1000 Spectrophotometer.

extract_protocol: Total RNA, including miRNA, was extracted using a QIAzol Lysis reagent (Qiagen, Valencia, CA, USA) and a miRNeasy Mini Kit (Qiagen) according to the manufacturer’s instructions. RNA was quantified using a NanoDrop-1000 spectrophotometer and quality was monitored with the Agilent 2100 Bioanalyzer (Agilent Technologies, Santa Clara, CA).

value: normal endometrial tissue


title: EMca_NORMAL_45

description: normal endometrial tissues_45


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G08_S80_comb


title: EMca_ENDOMETRIOID_38

description: endometrial endometrioid adenocarcinomas_G1_38


title: EMca_NORMAL_46

description: normal endometrial tissues_46


title: EMca_ENDOMETRIOID_39

description: endometrial endometrioid adenocarcinomas_G1_39


title: cy81_FNA_CD45_neg_F12_S1032_comb


title: cy79_p4_CD45_neg_PDL1_neg_F02_S1118_comb


title: CY89FNAQ2_F12_S456_comb


title: EMca_ENDOMETRIOID_40

description: endometrial endometrioid adenocarcinomas_G1_40


title: EMca_NORMAL_48

description: normal endometrial tissues_48


title: EMca_ENDOMETRIOID_42

description: endometrial endometrioid adenocarcinomas_G1_42


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_E04_S52_comb


title: EMca_ENDOMETRIOID_37

description: endometrial endometrioid adenocarcinomas_G1_37


title: EMca_ENDOMETRIOID_41

description: endometrial endometrioid adenocarcinomas_G1_41


title: EMca_ENDOMETRIOID_43

description: endometrial endometrioid adenocarcinomas_G1_43


title: EMca_ENDOMETRIOID_44

description: endometrial endometrioid adenocarcinomas_G1_44


title: CY89CORE11_H06_S186_comb


title: cy79_p3_CD45_neg_PDL1_neg_B03_S207_comb


title: CY88_3_G11_S659_comb


title: cy53_1_CD45_neg_B07_S307_comb


title: Cy81_Bulk_CD45_A11_S107_comb


title: EMca_ENDOMETRIOID_36

description: endometrial endometrioid adenocarcinomas_G1_36


title: CY88_5_C05_S701_comb


title: CY88_5_F05_S737_comb


title: cy79_p4_CD45_neg_PDL1_neg_B10_S1078_comb


title: EMca_ENDOMETRIOID_34

description: endometrial endometrioid adenocarcinomas_G2_34


title: EMca_ENDOMETRIOID_35

description: endometrial endometrioid adenocarcinomas_G1_35


title: EMca_ENDOMETRIOID_32

description: endometrial endometrioid adenocarcinomas_G2_32


title: EMca_ENDOMETRIOID_31

description: endometrial endometrioid adenocarcinomas_G2_31


title: EMca_ENDOMETRIOID_30

description: endometrial endometrioid adenocarcinomas_G2_30


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_A10_S106_comb


title: EMca_ENDOMETRIOID_33

description: endometrial endometrioid adenocarcinomas_G2_33


title: cy79_p5_CD45_neg_PDL1_pos_H11_S767_comb


title: cy80_CD45_neg_B04_S880_comb


title: Cy71_CD45_B12_S504_comb


title: cy78_CD45_neg_3_A12_S684_comb


title: EMca_ENDOMETRIOID_26

description: endometrial endometrioid adenocarcinomas_G3_26


title: EMca_ENDOMETRIOID_29

description: endometrial endometrioid adenocarcinomas_G3_29


title: EMca_ENDOMETRIOID_28

description: endometrial endometrioid adenocarcinomas_G3_28


title: EMca_NORMAL_23

description: normal endometrial tissues_23

scan_protocol: The arrays were scanned with an Agilent microarray scanner (Agilent Technologies) using high dynamic range settings as specified by the manufacturer


title: EMca_SEROUS_20

description: endometrial serous adenocarcinomas(s1-s21)_20

value: endometrial serous adenocarcinoma


title: cy79_p4_CD45_neg_PDL1_pos_D08_S428_comb

description:
Full-length RNAseq (SMART-Seq2) reads.
processed data file: counts.csv
processed data file: tpm.csv
processed data file: cell.annotations.csv


title: EMca_NORMAL_24

description: normal endometrial tissues_24


title: EMca_NORMAL_22

description: normal endometrial tissues_22


title: EMca_ENDOMETRIOID_25

description: endometrial endometrioid adenocarcinomas_G3_25


title: EMca_ENDOMETRIOID_27

description: endometrial endometrioid adenocarcinomas_G3_27


title: cy79_p5_CD45_neg_PDL1_neg_A07_S775_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_C05_S317_comb


title: EMca_SEROUS_21

description: endometrial serous adenocarcinomas(s1-s21)_21


title: CY89CORE11_D11_S143_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_D07_S331_comb


title: EMca_SEROUS_18

description: endometrial serous adenocarcinomas(s1-s21)_18


title: cy80_CD45_neg_E06_S918_comb


title: Cy80_II_CD45_D04_S904_comb


title: cy79_p4_CD45_neg_PDL1_pos_C05_S413_comb


title: cy79_p4_CD45_neg_PDL1_neg_D04_S1096_comb


title: EMca_SEROUS_19

description: endometrial serous adenocarcinomas(s1-s21)_19


title: EMca_SEROUS_16

description: endometrial serous adenocarcinomas(s1-s21)_16


title: EMca_SEROUS_14

description: endometrial serous adenocarcinomas(s1-s21)_14


title: EMca_SEROUS_15

description: endometrial serous adenocarcinomas(s1-s21)_15


title: EMca_SEROUS_11

description: endometrial serous adenocarcinomas(s1-s21)_11


title: CY89CORE11_C08_S128_comb


title: EMca_SEROUS_9

description: endometrial serous adenocarcinomas(s1-s21)_1


title: EMca_SEROUS_10

description: endometrial serous adenocarcinomas(s1-s21)_10


title: EMca_SEROUS_12

description: endometrial serous adenocarcinomas(s1-s21)_12


title: cy79_p5_CD45_neg_PDL1_pos_H03_S759_comb


title: EMca_SEROUS_17

description: endometrial serous adenocarcinomas(s1-s21)_17


title: EMca_SEROUS_13

description: endometrial serous adenocarcinomas(s1-s21)_13


title: cy78_CD45_neg_3_C01_S697_comb


title: CY88_5_C08_S704_comb


title: cy79_p5_CD45_neg_PDL1_neg_A11_S779_comb


title: EMca_SEROUS_7

description: endometrial serous adenocarcinomas(s1-s21)_7

data_processing: Microarray results were extracted using Agilent Feature Extraction software Ver. 9.5.3.1 (Agilent Technologies) and analyzed using Gene Spring GX 7.3.1 software (Agilent Technologies) to obtain gene expression ratios. Ratio of intensities values above or less than 2.0 were considered significant for upregulated or downregulated genes


title: cy79_p4_CD45_neg_PDL1_neg_B03_S1071_comb


title: cy82_CD45_neg_3_D09_S813_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_B06_S306_comb


title: cy82_CD45_neg_2_H12_S288_comb

value: CAF


title: CY89A_CD45_POS_10_A07_S199_comb


title: EMca_SEROUS_8

description: endometrial serous adenocarcinomas(s1-s21)_8


title: cy79_p4_CD45_neg_PDL1_neg_E01_S1105_comb

description:
Full-length RNAseq (SMART-Seq2) reads.
processed data file: counts.csv
processed data file: tpm.csv
processed data file: cell.annotations.csv


title: WT2: Myb-sufficient CD8+ T cells replicate 2

city: Bethesda

first: Luca

last: Gattinoni

state: MD

address: 10 Center Drive

department: Center for Cancer Research

institute: National Cancer Institute

data_processing:
Illumina Casava1.7 software used for basecalling.
Reads Per Kilobase of exon per Megabase of library size (RPKM) were calculated using edgeR package
log2-transformed RPKM
Genome_build: mm9
Supplementary_files_format_and_content: tab-delimited text files include log2-transformed RPKM values for all samples

organism: Mus musculus

source_name: CD8+ T cells

growth_protocol: pmel-1 Myb+/+ and pmel-1 Myb−/− CD8+ T cells were harvested 5 days after adoptive transfer into mice infected with gp100-VV

extract_protocol:
RNA was isolated with an RNeasy Mini kit (Qiagen).
RNA concentration was determined with the Qubit RNA broad range assay in the Qubit Fluorometer (Invitrogen) and RNA integrity was determined with Eukaryote Total RNA Nano Series II Chip on a 2100 Bioanalyzer (Agilent). RNA-seq libraries were prepared from 4 μg of total RNA via the TruSeq RNA sample prep kit according to manufacturer’s protocol (Illumina). In brief, oligo-dT purified mRNA was fragmented and subjected to first and second strand cDNA synthesis. cDNA fragments were blunt-ended, ligated to Illumina adaptors, and PCR amplified to enrich for the fragments ligated to adaptors.
The resulting cDNA libraries were verified and quantified on Agilent Bioanalyzer and paired-end (2x75 bp) RNA-seq was conducted with the GAIIx Genome Analyzer (Illumina).

treatment_protocol: KLRG1−CD62L− cells sorted with a purity > 99% by Flow sorter

tag: strain

value: Spleen

tag: origin

value: ex vivo

tag: genotype

value: Myb WT

value: CD8+ T cells


title: WT3: Myb-sufficient CD8+ T cells replicate 3


title: EMca_SEROUS_6

description: endometrial serous adenocarcinomas(s1-s21)_6


title: EMca_SEROUS_4

description: endometrial serous adenocarcinomas(s1-s21)_4


title: WT1: Myb-sufficient CD8+ T cells replicate 1


title: Cy81_Bulk_CD45_E03_S147_comb


title: CY89NEG_D12_S48_comb


title: KO3: Myb-deficient CD8+ T cells replicate 3

value: Myb KO


title: KO1: Myb-deficient CD8+ T cells replicate 1


title: cy79_p4_CD45_neg_PDL1_neg_A08_S1064_comb

value: Tirosh


title: KO2: Myb-deficient CD8+ T cells replicate 2


title: cy78_CD45_neg_1_D12_S528_comb


title: cy80_CD45_neg_D11_S911_comb


title: EMca_SEROUS_5

description: endometrial serous adenocarcinomas(s1-s21)_2


title: cy79_p5_CD45_neg_PDL1_neg_A12_S780_comb


title: EMca_SEROUS_1


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_H09_S189_comb


title: EMca_SEROUS_3

description: endometrial serous adenocarcinomas(s1-s21)_3


title: cy78_CD45_neg_1_D09_S525_comb


title: EMca_SEROUS_2


title: CY89CORE11_A09_S105_comb


title: cy79_p3_CD45_neg_PDL1_neg_A11_S203_comb


title: CY89CORE11_F07_S163_comb


title: CY89NEG_E02_S50_comb


title: Cy80_II_CD45_F11_S935_comb


title: cy79_p4_CD45_neg_PDL1_pos_G03_S459_comb


title: cy78_CD45_neg_3_F12_S744_comb


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_B09_S117_comb


title: CY89NEG_A02_S2_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 19

city: Budapest

first: Zoltan

last: Pos

address: 4 Nagyvarad ter

department: Dept. of Genetics, Cell- and Immunobiology

country: Hungary

institute: Semmelweis University

description: Batch 2

hyb_protocol: Cy3-labeled amplified cRNA was hybridized to human GE 4x44K v2 whole-genome microarrays (Agilent) and scanned on an Agilent Microarray Scanner. Raw data were retrieved with the Feature Extraction software (Agilent

scan_protocol: Samples were scanned on an Agilent Microarray Scanner.

data_processing: Batch effect was removed by distance weighted discrimination. Analyses were performed using BRB-ArrayTools developed by Dr. Richard Simon and the BRB-ArrayTools Development Team. All genes flagged as not detected, displaying batch adjusted signal intensities lower than log2=1, not detected in all samples of any experimental groups, or not displaying 2-fold change in at least one experimental group in either direction from the gene’s median value, were censored. The remaining gene set (1981 genes) was analyzed by Two-way repeated measures ANOVA and Benjamini-Hochberg multiple testing correction (FDR<0.01) to identify differentially expressed genes (DEGs).

source_name: Peripheral blood

label_protocol: Sample integrity and yield were assessed on a 2100 Bioanalyzer using an RNA 6000 Pico Kit. Three thousand pg total RNA per sample was amplified in two rounds and Cy3-labeled by the Arcturus RiboAmp HS PLUS, Cy3 labeling Kit.

growth_protocol: Blood samples were collected from 20 selected allo-HSCT patients of the Dept. of Hematology and Stem Cell Transplantation, St. Istvan and St Laszlo Hospital, Budapest, Hungary for research purposes, with informed consent and IRB approval. Patients were recruited to create four age- and gender-matched groups that developed no acute GvHD, acute cutaneous GvHD, acute gastrointestinal GvHD, or both acute and gastrointestinal GvHD after allo-HSCT (n=5 each). Samples were collected at the time of diagnosis before any GvHD-specific treatment had been commenced with (GvHD groups), or around day 30 post allo-HSCT (no-GvHD group)

extract_protocol: Cells were sorted directly into RLT Plus lysis buffer. Total RNA was isolated using an RNEasy Plus Micro kit.

treatment_protocol: Peripheral blood was collected using Acid Citrate Dextrose (ACD-A) tubes. PBMCs were isolated by density centrifugation, and stained with LIVE/DEAD® Fixable Dead Cell Stain Near-IR (Thermo), anti-human CD8β-APC, anti-human Cutaneous Lymphocyte Antigen (CLA)-FITC, and anti-human Integrin β7 (ITGB7)-PE antibodies. Three-way sorting of PBMCs was done on a BD FACSAria III sorter. Skin-homing LIVE/DEAD®-/CD8b+/CLA+ T cells, gut-homing LIVE/DEAD®-/CD8b+/ITGB7+ T cells, and LIVE/DEAD®-/CD8b+/CLA-/ITGB7- T cells, the latter serving as reference, were acquired with help of the FACSDiva software (BD).

tag: agvhd developed

value: Cutaneous + Gastrointestinal

tag: t cell subset

tag: patient no.


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Absent_Patient No. 14

description: Batch 2

value: Absent


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Gastrointestinal_Patient No. 20

description: Batch 2

value: Gastrointestinal


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Absent_Patient No. 16

description: Batch 2


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous_Patient No. 13

description: Batch 2

value: Cutaneous


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 15

description: Batch 2


title: cy81_FNA_CD45_neg_G09_S1041_comb

value: Mal


title: cy79_p5_CD45_neg_PDL1_neg_F02_S830_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Gastrointestinal_Patient No. 20

description: Batch 2


title: cy78_CD45_neg_3_A05_S677_comb


title: Cy71_CD45_B03_S495_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous_Patient No. 13

description: Batch 2


title: cy82_CD45_neg_1_D05_S233_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Gastrointestinal_Patient No. 18

description: Batch 2


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous_Patient No. 17

description: Batch 2


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 19

description: Batch 2


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Gastrointestinal_Patient No. 20

description: Batch 2


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Gastrointestinal_Patient No. 18

description: Batch 2


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Absent_Patient No. 14

description: Batch 2


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous_Patient No. 17

description: Batch 2


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Gastrointestinal_Patient No. 18

description: Batch 2


title: cy81_FNA_CD45_neg_G03_S1035_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 15

description: Batch 2


title: cy79_p5_CD45_neg_PDL1_pos_E06_S726_comb


title: cy81_Bulk_CD45_neg_F05_S161_comb

value: Undetermined


title: cy79_p5_CD45_neg_PDL1_pos_B04_S688_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 19

description: Batch 2


title: Cy80_II_CD45_A09_S873_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Absent_Patient No. 16

description: Batch 2


title: CY88_3_E10_S634_comb


title: cy79_p5_CD45_neg_PDL1_neg_F11_S839_comb


title: CY89CORE11_G08_S176_comb


title: cy80_CD45_neg_D09_S909_comb


title: Cy80_II_CD45_B12_S888_comb


title: cy79_p4_CD45_neg_PDL1_pos_F09_S453_comb


title: cy79_p3_CD45_neg_PD1_pos_AS_C3_R1_H02_S374_comb


title: CY88_5_B01_S685_comb


title: cy79_p4_CD45_neg_PDL1_pos_E02_S434_comb


title: cy79_p4_CD45_neg_PDL1_neg_C11_S1091_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous_Patient No. 17

description: Batch 2


title: cy79_p4_CD45_neg_PDL1_pos_C10_S418_comb


title: cy82_CD45_pos_2_F11_S551_comb


title: CY88_5_B07_S691_comb


title: cy78_CD45_neg_1_F05_S545_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous_Patient No. 13

description: Batch 1


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Absent_Patient No. 16

description: Batch 2


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 15

description: Batch 2


title: CY89FNAQ2_C01_S409_comb


title: cy79_p4_CD45_neg_PDL1_neg_G07_S1135_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Absent_Patient No. 11

description: Batch 1


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 10

description: Batch 1


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous_Patient No. 9

description: Batch 1


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Absent_Patient No. 14

description: Batch 2


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Gastrointestinal_Patient No. 12

description: Batch 1


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Gastrointestinal_Patient No. 12

description: Batch 1


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous_Patient No. 9

description: Batch 1


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Gastrointestinal_Patient No. 12

description: Batch 1


title: CY89NEG_A03_S3_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Absent_Patient No. 11

description: Batch 1


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Absent_Patient No. 11

description: Batch 1


title: cy84_Primary_CD45_neg_E12_S1020_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Gastrointestinal_Patient No. 5

description: Batch 3


title: Cy71_CD45_E10_S538_comb


title: CY88_5_B03_S687_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 10

description: Batch 1


title: cy79_p4_CD45_neg_PDL1_pos_A11_S395_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G06_S78_comb


title: Cy80_II_CD45_F07_S931_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 10

description: Batch 1


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_D10_S46_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous_Patient No. 8

description: Batch 3


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Absent_Patient No. 6

description: Batch 3


title: cy79_p4_CD45_neg_PDL1_pos_D02_S422_comb


title: CY89CORE11_F03_S159_comb

value: Endo.


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 2

description: Batch 3


title: Cy71_CD45_D09_S525_comb


title: cy79_p4_CD45_neg_PDL1_neg_H10_S1150_comb


title: cy79_p4_CD45_neg_PDL1_neg_H03_S1143_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Gastrointestinal_Patient No. 4

description: Batch 3


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous_Patient No. 3

description: Batch 3


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Gastrointestinal_Patient No. 5

description: Batch 3


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Absent_Patient No. 6

description: Batch 3


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_C07_S127_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 7

description: Batch 3


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 7

description: Batch 3


title: cy84_Primary_CD45_neg_A03_S963_comb


title: Cy71_CD45_F10_S550_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_E11_S59_comb


title: CY89FNAQ2_B10_S406_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Absent_Patient No. 1

description: Batch 3


title: cy79_p5_CD45_neg_PDL1_pos_F02_S734_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous_Patient No. 8

description: Batch 3


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Gastrointestinal_Patient No. 4

description: Batch 3


title: Cy80_II_CD45_B06_S882_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Absent_Patient No. 6

description: Batch 3


title: Cy81_Bulk_CD45_B01_S109_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 7

description: Batch 3


title: cy80_CD45_neg_D10_S910_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous_Patient No. 3

description: Batch 3


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 2

description: Batch 3


title: shTopBP1_diff72_rep2

city: Chicago

first: Yan

last: Li

state: IL

address: 900 East 57th St.

department: Center for Research Informatics

institute: The University of Chicago

data_processing:
Raw sequencing QC assessement: FastQC v0.115
Alignment: STAR v2.5.3a
Post alignement QC assessment: RSeQC and Picard tools v2.9.0
Gene transcripts assembly: featureCounts
Differentially expressed genes analysis: edgeR
Genome_build: GENCODE human genome model: GRCh38 v27
Supplementary_files_format_and_content: tab-delimited text files include gene features raw counts values summarized by featureCounts for each Sample.

source_name: Keratinocytes

growth_protocol: Cells were cultured in E-media along with the fibrablast feeders, and differentiated in high-calcium for 3 days

extract_protocol:
Cells were washed with .5mM EDTA-containing PBS and extracted for total RNA by Qiagen Rneasy kit. The RNA was treated by Dnase and purified through the column before the experiments.
RNA libraries were prepared for sequencing using standard Illumina protocols

tag: tissue source

value: CIN I biopsy

value: keratinocytes

tag: hpv status

tag: knockdown

value: TopBP1 knockdown


title: Cy80_II_CD45_F12_S936_comb


title: shTopBP1_diff72_rep1


title: Cy71_CD45_A10_S490_comb


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Gastrointestinal_Patient No. 5

description: Batch 3


title: Ly/CD8b+/ITGB7+ T cells_aGvHD developed: Cutaneous_Patient No. 3

description: Batch 3


title: scramble_diff72_rep1

value: scramble control


title: cy79_p4_CD45_neg_PDL1_pos_B10_S406_comb


title: scramble_diff72_rep2


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Gastrointestinal_Patient No. 4

description: Batch 3


title: cy79_p5_CD45_neg_PDL1_neg_G07_S847_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous + Gastrointestinal_Patient No. 2

description: Batch 3


title: cy53_1_CD45_neg_D06_S330_comb


title: cy79_p4_CD45_neg_PDL1_neg_B09_S1077_comb


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Cutaneous_Patient No. 9

description: Batch 1


title: cy79_p4_CD45_neg_PDL1_neg_D06_S1098_comb


title: Ly/CD8b+/CLA-/ITGB7- T cells_aGvHD developed: Cutaneous_Patient No. 8

description: Batch 3


title: Ly/CD8b+/CLA+ T cells_aGvHD developed: Absent_Patient No. 1

description: Batch 3


title: WT p2hNCC

city: Koeln

first: Milos

last: Nikolic

state: Nordrhein-Westfalen

address: Robert Koch Str. 21

country: Germany

institute: Center for Molecular Medicine Cologne

data_processing:
UMIs were counted using cellranger-2.1.0 with default parameters on hg19.
Initial dimensionality reduction, clustering and visualization was generated with cellranger-2.1.0 and cellrangerRkit_2.0.0 within R-3.4.0.
Counts were aggregated into a single matrix with default normalization (“--normalize=mapped”) by cellranger-2.1.0.
Matrix was further processed with monocle_2.6.4 within R-3.4.0.
Dropouts were corrected with Rmagic_1.3.0 (MAGIC) within R-3.4.0 for correlation analysis.
Genome_build: hg19
Supplementary_files_format_and_content: File to visualize gene expression in all the sequenced single cells using the Luope Cell Browser software (10xGenomics)

molecule: polyA RNA

source_name: WT p2hNCC

growth_protocol: WT hiPSC and BOFS hiPSC lines were grown in tissue culture plates coated with GelTrex (ThermoFisher Scientific, #1413301) using either mTeSRTM1 (STEMCELL Technologies, #05870) or StemMACS iPS-Brew XF medium (Miltenyl Biotec, #130-104-368). The medium of the cells was changed daily. hiPSC were differentiated into hNCC experiments as previously reported (Bajpai et al;2010). Briefly, hiPSCs were washed twice with PBS  and treated with 2mg/mL Collagenase solution (Life Technologies, #17104-019) in DMEM KO Medium to detach hiPSC colonies from the plate surface. 2mL of Collagenase solution was used for one well of a 6-well plate, followed with incubation period at 37C. After about one hour, collagenase solution was carefully aspirated and PBS was added to collect all the colonies into a 15mL falcon tube. Following another round of PBS washing, fresh pre-warmed hNCC Differentiation Medium  was added and resuspended to break big colonies into relatively smaller cell clumps. hiPSC clumps were then plated in petri dishes and kept at 37⁰C, which  after 2-3 days form floating Embryoid Bodies (EB) formation . Between day 6 and 9, EBs attached and gave rise to hNCC outgrowths. hNCC were collected at day 11 (d11hNCC) and then expanded for two passages (p2hNCC) according to a recent protocol (Prescott et al; 2015). The hNCC differentiation medium was changed every 2-3 days.

extract_protocol:
Cells were dissociated to generate a suspension of viable single cells. The suspension was centrifuged at 300 rcf for 5 min and the cell pellet was washed in 1 ml of 1xPBS 0.04% BSA. Cells were centrifuged again and resuspended in 1xPBS 0.04% BSA to the desired cell concentration. Cells were passed throught  strainer and cell concentration was determined again. cDNA synthesis and library preparation was performed following the 10x Single Cell 3’ Reagent Kit protocol on a 10xGenomics Chromium instrument. Briefly, cells were partitioned in nanoliter-scale Gel Bead-In-Emulsions (GEMs) containing, in addition to a single cell, a master mix and primers that consist of (i) an Ilumina R1 sequence, (ii) a 16bp 10x barcode unique for each cell, (iii) a 10 bp Unique Molecular Identifier (UMI) and (iv) a poly-dT sequence. Full length barcoded cDNA were generated from poly-adenylated mRNAs. GEMs were broken and the pooled fractions were recovered.
The cDNAs were exposed to enzymatic fragmentation and size selection prior to library construction and P5, P7, a sample index and an Ilumina R2 primer were added during library construction. The final libraries containing the P5 and P7 primers were used for Ilumina bridge amplification. Finally, R1 and R2 primers were used for paired-end Ilumina sequencing.

treatment_protocol: BOFS hiPSC were derived from fibroblasts isolated from a BOFS patient carrying a 88Mb de novo heterozygousinversion in chromosome 6.

tag: cell line

value: WT hiPSC

value: WT

tag: treatment

value: hiPSC differentiation into hNCC (passage 2)


title: BOFS p2hNCC

source_name: BOFS p2hNCC

value: BOFS hiPSC

value: BOFS 88Mb inversion


title: del0.4Mb#2_rep2_d11hNCC

data_processing:
Basic read quality check was performed using FastQC (Babraham Bioinformatics) and read statistics were obtained with SAMtools
Reads were mapped to the human  reference assembly (hg38) using TopHat2
Read count means, fold-change (FC) and p-values were calculated with DEseq2
gene expression for the individual samples was calculated with Cufflinks as FPKMs.
Genome_build: hg38
Supplementary_files_format_and_content: Txt file containing Read count means, fold-change (FC) and p-values  calculated with DEseq2 and FPKMs calculated with Cufflinks for human Ensembl Genes used in GREAT (McLean et al., 2010).

source_name: del0.4Mb d11hNCC

extract_protocol:
Total RNA was isolated using Tripure reagent according to the manufacturer’s instructions (Roche). Libraries were prepared with the RNA sample preparation kit (TruSeq v2; Ilumina).
RNA libraries were prepared for sequencing using standard Illumina protocols

value: WT hiPSC#1

value: 0.4Mb deletion

value: hiPSC differentiation into hNCC (day11)


title: del0.4Mb#2_rep1_d11hNCC


title: del0.4Mb#1_rep2_d11hNCC


title: cy84_Primary_CD45_neg_G07_S1039_comb

tag: tumor-of-origin

tag: treatment-group

value: Tirosh


title: cy81_Bulk_CD45_neg_E08_S152_comb

tag: cohort

tag: cell type


title: cy81_Bulk_CD45_neg_B03_S111_comb


title: del0.4Mb#1_rep1_d11hNCC


title: WT#1_rep3_d11hNCC

source_name: WT d11hNCC


title: cy79_p3_CD45_neg_PDL1_neg_F07_S259_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_C10_S34_comb


title: cy80_CD45_neg_H03_S951_comb


title: WT#1_rep2_d11hNCC


title: cy78_CD45_neg_1_H02_S566_comb


title: WT#1_rep1_d11hNCC


title: CY88_5_C09_S705_comb


title: BOFS_p2hNCC_TFAP2A_Enh100

library_source: genomic

data_processing:
Library strategy: 4C
Reads were assigned to samples based on the first 10 bases of the read. Subsequently, the primer sequence was removed from the read and the remaining sequence was trimmed to 36 bases. These 36 bases were aligned to the human (hg19) or chicken (gg3) reference genomes  using Bowtie 0.12.7.
The resulting mapped reads were analyzed with R3C-seq (Thongjuea et al., 2013) in order to generate RPM (reads per million) normalized bedgraph files for downstream visualization and analysis.
Genome_build: hg19

molecule: genomic DNA

growth_protocol: WT hiPSC and BOFS hiPSC lines were grown in tissue culture plates coated with GelTrex (ThermoFisher Scientific, #1413301) using either mTeSRTM1 (STEMCELL Technologies, #05870) or StemMACS iPS-Brew XF medium (Miltenyl Biotec, #130-104-368). The medium of the cells was changed daily. hiPSC were differentiated into hNCC experiments as previously reported (Bajpai et al;2010). Briefly, hiPSCs were washed twice with PBS  and treated with 2mg/mL Collagenase solution (Life Technologies, #17104-019) in DMEM KO Medium to detach hiPSC colonies from the plate surface. 2mL of Collagenase solution was used for one well of a 6-well plate, followed with incubation period at 37C. After about one hour, collagenase solution was carefully aspirated and PBS was added to collect all the colonies into a 15mL falcon tube. Following another round of PBS washing, fresh pre-warmed hNCC Differentiation Medium  was added and resuspended to break big colonies into relatively smaller cell clumps. hiPSC clumps were then plated in petri dishes and kept at 37⁰C, which  after 2-3 days form floating Embryoid Bodies (EB) formation . Between day 6 and 9, EBs attached and gave rise to hNCC outgrowths. hNCC were collected at day 11 (d11hNCC) or expanded for two passages (p2hNCC) according to a recent protocol (Prescott et al; 2015). The hNCC differentiation medium was changed every 2-3 days.

extract_protocol:
4C-seq assays were performed as previously described (Splinter et al., 2012; Stadhouders et al., 2013; Cruz-Molina et al., 2017) with slight modifications. Approximately 5-10 million  p2hNCC were crosslinked with 1% formaldehyde during 20 minutes and quenched with 0.125M glycine for 10 min. Cells were washed with PBS and resuspended in lysis buffer (50 mM Tris–HCl pH 7.5, 150 mM NaCl, 5 mM EDTA, 0.5% NP-40, 1% TX-100 and 1X protease inhibitors) during 10 min on ice.  Following centrifugation for 5 min at 650g (4 °C), nuclei were re-suspended in 0.5 ml of 1.2X restriction buffer with 0.3% SDS and incubated at 37 °C and 900 rpm for 1h. After that, Triton X-100 was added to a final concentration of 2% followed by 1h incubation at 37 °C and 900 rpm. Afterwards, chromatin was digested overnight at 37 °C and 900 rpm with 400 U of NlaIII (R0125L, NEB). NlaIII was inactivated by adding SDS to a final concentration of 1.6% and incubating the mixture for 20 min at 65 °C while shaking (900 rpm). The digested chromatin was transferred to 50-ml tubes and 6.125 ml of 1.15X ligation buffer (50 mM Tris-HCl pH 7.6, 10 mM MgCl2, 1 mM ATP, 1mM DTT) were added. Triton X-100 was also added to a final concentration of 1% and the resulting solution was incubated for 1 h at 37 °C while shaking gently. After that, digested chromatin was ligated with 100 U of T4 DNA ligase (15224-041, Life Technologies) for 8 h at 16 °C, followed by RNAse A treatment (300 μg, Peqlab) for 45 min at 37 °C. Subsequently, chromatin was de-crosslinked with 300 μg of Proteinase K (Peqlab) and overnight incubation at 65 °C. DNA was then purified by phenol/chloroform extraction followed by ethanol precipitation and re-suspension in 100 μl of water. At this step, the digestion and ligation efficiencies were evaluated by analysing a small fraction of the purified DNAs by agarose electrophoresis. The remaining DNA was digested with 50U of DpnII (R0543M, NEB) in 500 μl of 1x NEBuffer DpnII at 37 °C overnight. DNA samples were purified by phenol/chlorophorm extraction, followed by ethanol precipitation. Once purified, DNA samples were re-suspended in 500 μl of water and a second ligation was performed by adding 200 U of T4 DNA Ligase into a final volume of 14 ml 1X ligation buffer followed by overnight incubation at 16 °C. DNA samples were subjected to another round of phenol/chlorophorm extraction and ethanol precipitation, re-suspended in 100 μl of water and purified with a QIAgen PCR purification column (28104, QIAgen). The efficiencies of the second digestion and ligation were also evaluated by agarose electrophoresis.
4C samples were amplified by inverse PCR using primers located within different human (TFAP2A promoter, ENh480, Enh100, 6p24inv breakpoint) genomic regions and that included illumina adaptor sequences and short barcodes. The inverse PCRs were performed with the expand long template PCR system (11681842001, Roche) and 30 amplification cycles (94°C 2 min, 30x [94°C 10 sec, 60°C 1 min, 68°C 3 min], 68°C 5 min). The inverse PCR primers were designed as previously described (Stadhouders et al., 2013). Once amplified, 4C-seq libraries were sequenced on the HiSeq2500, generating reads of either 74 or 100 bp in length.

value: BOFS hiPSC cl1


title: WT_p2hNCC_TFAP2A_Enh100


title: cy79_p1_CD45_neg_PDL1_neg_AS_C4_R1_B04_S112_comb

value: Mal


title: BOFS_p2hNCC_TFAP2A_Enh480


title: WT_p2hNCC_TFAP2A_Enh480


title: CY88_5_F11_S743_comb


title: cy79_p1_CD45_neg_PDL1_pos_AS_C1_R1_G09_S81_comb


title: WT_p2hNCC_TFAP2A_prom


title: cy82_CD45_pos_1_H05_S569_comb

value: Undetermined


title: cy78_CD45_neg_3_C09_S705_comb


title: cy79_p4_CD45_neg_PDL1_pos_F11_S455_comb