title: METSIM5263

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM5571

status: Public on Apr 01 2013

type: SRA

city: Los Angeles

first: Mete

last: Civelek

state: CA

address: 675 Charles E. Young Dr. S. MRL 3220

department: Medicine

country: USA

institute: University of California Los Angeles

library_source: transcriptomic

data_processing:
Illumina Casava1.7 software used for basecalling.
Sequencing files were converted to FASTQ format using a custom Perl script. In order to assign the indexed reads to each METSIM subject, a Python script was used to partition the FASTQ file for each lane into multiple FASTQ files, each of which corresponded to one individual. To be included in the partitioned file, a read had to have an exact match to one of the 48 possible index sequences, unambiguously identifying the individual from whom the read originated. Reads which did not exactly match an index sequence were discarded.
The reads were then aligned to the hg19 version of the genome using the Novoalign tool with the following settings: -l16 -t30 -h90 -rA -R 1 -m -g 200 –k.  Novoalign software trims the adapter sequences while aligning.
We used the Bioconductor package GenomicRanges for R (v.2.14.0) to count the number of reads with alignment coordinates that overlap the coordinates of known mature miRNAs. Whenever a read mapped to 'x' genomic loci, the read would contribute a count of 1/x to those regions. The genomic coordinates for known mature miRNAs were downloaded from miRBase version 18.
To enable comparison of counts between samples, we normalized the expression values by dividing the counts for a given mature miRNA by the sum of all the miRNA counts for the corresponding individual. For subsequent analysis, we considered the expression levels of 356 miRNAs that had at least 5 reads in half of the study participants.
Genome_build: hg19
Supplementary_files_format_and_content: tab-delimited text files include unnormalized weighted counts for each miRNA

molecule: total RNA

organism: Homo sapiens

source_name: adipose tissue

extract_protocol:
Abdominal subcutaneous adipose tissue was obtained with needle biopsies. Total RNA was isolated from the adipose tissue using Qiagen miRNeasy kit according to manufacturer’s instructions. RNA Integrity Number (RIN) values were assessed with the Agilent Bioanalyzer 2100 instrument. Samples with RIN values greater than 7.0 were used for transcriptional profiling.
Small RNA libraries were prepared using  the Illumina  TruSeq Small RNA protocol utilizing up to 48 unique index sequences (Illumina Catalog Number FC-102-1009). For two samples (METSIM490 and METSIM6589) we also prepared small RNA libraries using Illumina Small RNA v1.5 sample preparation protocol (Catalog # FC-930-1501)

treatment_protocol: We analyzed samples from 200 male human subjects that are part of the METSIM (METabolic Syndrome In Men) study. The population-based cross-sectional METSIM study included 10,197 men, aged from 45 to 73 years, who were randomly selected from the population register of the Kuopio town in eastern Finland (population 95,000). Every participant had a 1-day outpatient visit to the Clinical Research Unit at the University of Kuopio, including an interview on the history of previous diseases and current drug treatment and an evaluation of glucose tolerance and cardiovascular risk factors. After 12 hours of fasting, a 2-h oral 75-g glucose tolerance test was performed and the blood samples were drawn at 0, 30 and 120 min. Plasma glucose was measured by enzymatic hexokinase photometric assay (Konelab Systems reagents; Thermo Fischer Scientific, Vantaa, Finland). Insulin was determined by immunoassay (ADVIA Centaur Insulin IRI no. 02230141; Siemens Medical Solutions Diagnostics, Tarrytown, NY). Height and weight were measured to the nearest 0.5 cm and 0.1 kg, respectively. Waist (at the midpoint between the lateral iliac crest and lowest rib) and hip circumference (at the level of the trochanter major) were measured to the nearest 0.5 cm. Body composition was determined by bioelectrical impedance (RJL Systems) in subjects in the supine position after a 12-hour fast.

tag: age

tag: tissue

value: adipose tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM5352

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM4644

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM5521

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM4542

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: Cavefish_eye

city: Beijing

first: Fanwei

last: Meng

address: 1 Beichen West Road,Chaoyang District

department: State Key Laboratory of Biomembrane and Membrane Biotechnology

country: China

institute: Institue of Zoology, Chinese Academy of Sciences

data_processing:
Illumina Casava1.7 software used for basecalling.
Sequenced reads were trimmed for adaptor sequence, and masked for low-complexity or low-quality sequence, then de novo assembled or mapped to de novo assembled transcriptome using bowtie v0.12.2 with parameters -v 3 -k 1 -e 100 -a  --best
Reads Per Kilobase of exon per Megabase of library size (RPKM (Reads Per Kilobase of exon per Million mapped sequence reads) were calculated using a protocol from Mortazavi et al., Nat Methods , 2008. In short, we merged the number of reads of surface fish and cavefish that mapped to the same unigene of either our Sinocyclocheilus transcriptome or the zebrafish unigene database, and converted mapped read numbers to RPKM values.
Genome_build: de novo assembled Sinocyclocheilus transcriptome
Supplementary_files_format_and_content: tab-delimited text files include RPKM values for each Sample.

organism: Sinocyclocheilus anophthalmus

source_name: eye

extract_protocol: Total RNA was isolated using a TRIzol reagent (Invitrogen) from whole eye and brain of adult surface and cave species respectively. Two individuals were used in each species. Oligo(dT) selection was performed by using MicroPoly(A) PuristTM (Ambion) according to the manufacturer's protocol. Superscript III First-Strand Synthesis System (Invitrogen) was used to create first-strand cDNA. The second-strand cDNA was synthesized using random primers and Klenow exo- polymerase (Epicentre). cDNA was sheared to short fragments with Biorupter® Sonicator, and then the fragments were connected with sequencing adapters. After size selection, suitable fragments were used as templates for PCR amplification. Finally, four libraries (200 – 400 bp insert) were sequenced using Illumina sequencer GA-II paired-end 80-nt or HiSeq 2000 paired-ed 100-nt (Illumina Inc., San Diego, CA, USA).

tag: tissue

value: eye

tag: age

value: adult

tag: sample type

value: cavefish


title: METSIM4403

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: Cavefish_brain

source_name: brain

tag: tissue

value: brain

tag: age

tag: sample type


title: METSIM4257

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM4336

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM4245

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM4572

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM4137

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM5441

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM3923

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: swollen stolon BR2

city: Dundee

first: Runxuan

last: Zhang

state: Angus

address: Errol Road, Invergowrie

department: Information and Computational Sciences

country: United Kingdom

institute: The James Hutton Institute

data_processing:
remove adaptor and trimming by applying quality score threshold of 20 using Cutadapt 1.1
Remove ribosomal, transfer RNAs, snRNAs and snoRNAs using Cross_match and retain sequences between 17-35nt
Novel miRNA identification using mirDeep-P v1.3

organism: Solanum tuberosum

source_name: swollen stolon

growth_protocol: in vitro propagated Solanum tubrosum group Andigena (clone ADG573), 4 weeks long day (LD) in glasshouse

extract_protocol:
total RNA was extracted by Norgen palnt and fungi total RNA purification kit (Cat# 25800)
Illumina TruSeq Small RNA sample prep kit was used for library construction

treatment_protocol: plants transfered into LD and short day (SD) cabinets at 20oC and sample them after 8 days

tag: day length

value: short day

tag: biological replicate


title: swollen stolon BR3


title: METSIM5203

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: swollen stolon BR1

tag: day length

tag: biological replicate


title: METSIM4990

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2950

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2869

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: stolon SD BR3

source_name: stolon

tag: day length

tag: biological replicate


title: stolon SD BR2


title: stolon SD BR1


title: LD leaf BR2

source_name: leaf

value: long day


title: LD leaf BR3


title: LD leaf BR1


title: SD leaf BR1


title: METSIM2704

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2760

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2735

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2687

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2656

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2570

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2495

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2655

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2620

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2488

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: SD leaf BR3

tag: day length

tag: biological replicate


title: METSIM2426

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2415

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2775

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2786

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: Short Stationary Rep2 (40)

city: Castanet Tolosan

first: Erika

last: Sallet

address: 24 Chemin de Borde Rouge, CS 52627

department: Plant Health and the Environment

country: France

institute: INRA/CNRS

data_processing:
Reads were mapped to the genome using glint (Faraut T. and Courcelle E.; http://lipm-ioinfo.toulouse.inra.fr/download/glint/, unpublished) and parameters were as follow: matches with less than or equal to 2 mismatches, no gap allowed and a minimum length of 18 nt required. We removed all ambiguous matches (reads or read-pairs mapping to two different positions with the same best score) as well as matches of paired-end reads that were separated by more than 1kb.
Genome_build: Sinorhizobium meliloti 2011 submitted to Genbank (pending; GDSub21246)
Supplementary_files_format_and_content: To annotate the Sinorhizobium meliloti genome, we computed the local library specific transcription depth at each position of the sequence (of the chromosome GMI11495-Rm2011G.c and of the megaplasmids GMI11495-Rm2011G.a and GMI11495-Rm2011G.b). The three tabulated files are composed of 20 columns: column 1=position, column2=strand, columns 3-20=local transcription depth for a specific library.

organism: Sinorhizobium meliloti

source_name: Cultured bacteria stationary phase

growth_protocol: RNAs were extracted from bacteria in liquid cultures in exponential and stationary growth phases and from 10-day-old nodules in which bacteria were differentiated in nitrogen fixing bacteroids

extract_protocol:
Harvested cultured bacteria were resuspended and incubated in pre-warmed lysis buffer (1.4% SDS, 4 mM EDTA and 0.4 mg/ml proteinase K) for 20 minutes at 65°C. Lysed cells were then incubated at 4°C for 10 minutes in the presence of 1.5 volumes of 5 M NaCl. Following centrifugation, the pellet containing proteins and cell debris was separated from nucleic acids in the supernatant fraction that were subsequently precipitated by the addition of one volume of isopropanol. Nucleic acid-containing pellets were washed with 70% cold ethanol, dried and resuspended in RNAse free water. Total nucleic acids were processed with mirVana isolation kit (Ambion, Invitrogen) using the total RNA isolation procedure which allowed the extraction of both short and long RNAs. For plant material, root nodules were collected and frozen in liquid nitrogen before ground with a mortar and pestle, and then with a Retsch MM300 mill for 1 min. Total RNA was then immediately extracted with the mirVana Isolation Kit using the total RNA isolation procedure. Bacterial or nodule total RNA preparations were then treated with TURBO DNase (Ambion, Life technologies) to remove residual contaminant DNA. Total RNA preparations were depleted of ribosomal RNAs (rRNAs) by an oligocapture strategy derived from the Plant Ribominus kit (Invitrogen), in which oligonucleotide sets specifically designed to target M. truncatula and S.meliloti rRNAs, as well as the highly abundant S. meliloti tRNA_Ala were used. RNAs were separated in two fractions, short (< 200 nt) and long (> 200 nt), using Zymo Research RNA Clean & Concentrator™-5 columns (Proteigene).
Oriented sequencing with a RNA ligation procedure was carried out by Fasteris SA (Geneva, Switzerland) using procedures recommended by Illumina, with adaptors and amplification primers designed by Fasteris, unless specified (see below). For short RNAs, the Small RNA Sequencing Alternative v1.5 Protocol (Illumina) was used, RNAs were first treated with Tobacco Acid Pyrophosphatase to remove triphosphate at 5’ transcript ends, and purified on acrylamide gel before and after the adaptor ligation step. The 3’ adaptor was the Universal miRNA cloning linker (NEB). For long RNAs, a fragmentation step by zinc during 8 min was included, following the Illumina procedure. The size of selected inserts was 20-120 nt for short RNA libraries and 50-120 nt for long RNA libraries from cultured bacteria and 150-250 nt for long RNA libraries from nodules. Libraries were sequenced either in paired-end or single-end.

tag: development stage

value: stationary phase

tag: strain

value: Sinorhizobium meliloti 2011

tag: rna fraction

value: short (< 200 nucleotides)

tag: treatment

value: Tobacco Acid Pyrophosphatase (TAP)

tag: fragmentation

tag: selected insert size

value: 20-120 nucleotides


title: Short Stationary Rep1 (39)


title: METSIM2392

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2692

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)


title: METSIM2261

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: SD leaf BR2

tag: day length

tag: biological replicate


title: Long Stationary Rep2 (34)

tag: development stage

tag: strain

tag: rna fraction

value: long (>200 nucleotides)

tag: treatment

tag: fragmentation

value: yes

tag: selected insert size

value: 50-120 nucleotides


title: Long Stationary Rep1 (33)


title: METSIM2176

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)


title: Short Exponential Rep3 (38)

source_name: Cultured bacteria mid-exponential phase

tag: development stage

value: mid-exponential phase

tag: strain

tag: rna fraction

tag: treatment

tag: fragmentation

tag: selected insert size


title: Short Exponential Rep2 (37)


title: METSIM2126

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2474

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)


title: METSIM2165

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: Short Exponential Rep1 (36)

tag: development stage

tag: strain

tag: rna fraction

tag: treatment

tag: fragmentation

tag: selected insert size


title: Short Stationary Rep3 (41)


title: Long Exponential Rep2 (31)


title: METSIM2100

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)


title: METSIM2057

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM2019

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)


title: METSIM1984

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: log10 creatinine (umol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: Long Exponential Rep3 (32)

tag: development stage

tag: strain

tag: rna fraction

tag: treatment

tag: fragmentation

tag: selected insert size


title: Input (control)

city: Chicago

first: Dali

last: Han

state: IL

address: 5801 South Ellis Avenue

department: Department of Chemisty

institute: University of Chicago

library_source: genomic

data_processing:
base-calling: Sequencing tags were obtained from the Solexa single-end pipeline.
alignment: Raw data were Procressed by Soap2 with default parameters. Duplicate reads were filtered.
peak calling: Summary islands were detected by SICER(w=200,g=400) using the combined sequence reads from all four samples.
Genome_build: Mmul 051212 (rheMac2)
Supplementary_files_format_and_content: bed file columns: Column 1: chromosome, Column 2: start, Column 3: end, Column 4: mismatch, Column 5: not use, Column 6: orientation.
Supplementary_files_format_and_content: peak file columns: Column 1: chromosome, Column 2: start position, Column 3: end position, Column 4: read count of input reads, Column 5: read count of control reads, Column 6: p-value as calculated by SICER, Column 7: fold change, Column 8: FDR.  Peak file is linked as supplementary file on Series record.

molecule: genomic DNA

organism: Macaca mulatta

source_name: prefrontal cortex

extract_protocol:
The Rhesus macaque tissue samples were obtained from the Suzhou Experimental Animal Center (Suzhou, China). The animals lived in a family setting in a spacious (H x L x W: 3x5x3m3) and clean environment with exercise equipment, and were adequately fed three times (rice, corn and vegetable and nutritional supplements) per day.
Around 200 mg of Rhesus macaque PFC tissues were used for each ChIP reaction using an antibody raised against H3K4me2 (Millipore, 07-030).
The genomic DNA was extracted using exactly the same buffers and procedures with ChIP except for the IP process. In detail, aliquot amount of tissue from seven individuals were pooled and grounded into powder in liquid nitrogen. Then tissue cells were suspended in PBS and chemically cross-linked by adding formaldehyde solution to a final concentration of 1% for 15 min at room temperature. Cells were rinsed twice with 1xPBS, resuspended, lysed (1% SDS, 50 mM Tris pH 8.0, 5 mM EDTA, proteinase inhibitors), and sonicated to gain DNA fragments of in 300-500bp length on average. Samples were then centrifuged at 14,000 rpm for 10 min. The supernatant was diluted (20 mM Tris pH 8.0, 2 mM EDTA, 1% Trion X-100, 150 mM NaCl, proteinase inhibitors) and de-cross-linked by incubation at 65°C water bath overnight. The input DNA were then purified by treatment with RNaseA, proteinase K and multiple phenol:chloroform:isoamyl and alcohol extraction.
Chromatin from the frozen rhesus macaque prefrontal cortex tissue was fragmented by sonication and immunoprecipitated by the incubation with antibody against H3K4me2 (Millipore, 07-030), then DNA was purified for the next library construction. Library construction was following Illumina's protocol. Genomic DNA extracted from a pool of 7 macaque individuals including the four used for ChIP-seq was also sequenced as a control "input" sample.

tag: tissue

value: prefrontal cortex

tag: age

value: a pool of 7 macaque individuals of different ages, including the four used for ChIP-seq, was sequenced as a control "input"

tag: antibody


title: METSIM2338

value: adipose tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)


title: METSIM1937

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: H3K4me2_22yr

extract_protocol:
The Rhesus macaque tissue samples were obtained from the Suzhou Experimental Animal Center (Suzhou, China). The animals lived in a family setting in a spacious (H x L x W: 3x5x3m3) and clean environment with exercise equipment, and were adequately fed three times (rice, corn and vegetable and nutritional supplements) per day.
Around 200 mg of Rhesus macaque PFC tissues were used for each ChIP reaction using an antibody raised against H3K4me2 (Millipore, 07-030).
The genomic DNA was extracted using exactly the same buffers and procedures with ChIP except for the IP process. In detail, aliquot amount of tissue from seven individuals were pooled and grounded into powder in liquid nitrogen. Then tissue cells were suspended in PBS and chemically cross-linked by adding formaldehyde solution to a final concentration of 1% for 15 min at room temperature. Cells were rinsed twice with 1xPBS, resuspended, lysed (1% SDS, 50 mM Tris pH 8.0, 5 mM EDTA, proteinase inhibitors), and sonicated to gain DNA fragments of in 300-500bp length on average. Samples were then centrifuged at 14,000 rpm for 10 min. The supernatant was diluted (20 mM Tris pH 8.0, 2 mM EDTA, 1% Trion X-100, 150 mM NaCl, proteinase inhibitors) and de-cross-linked by incubation at 65°C water bath overnight. The input DNA were then purified by treatment with RNaseA, proteinase K and multiple phenol:chloroform:isoamyl and alcohol extraction.
Chromatin from the frozen rhesus macaque prefrontal cortex tissue was fragmented by sonication and immunoprecipitated by the incubation with antibody against H3K4me2 (Millipore, 07-030), then DNA was purified for the next library construction. Library construction was following Illumina's protocol. Genomic DNA extracted from a pool of 7 macaque individuals including the four used for ChIP-seq was also sequenced as a control “input” sample.

tag: tissue

tag: age

value: 22 yr

tag: antibody

value: Anti-dimethyl-Histone H3 (Lys4) Antibody [Millipore, catalog# 07-030]


title: METSIM1942

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)


title: H3K4me2_9yr

tag: tissue

tag: age

value: 9 yr

tag: antibody


title: METSIM1932

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: H3K4me2_26yr

tag: tissue

tag: age

value: 26 yr

tag: antibody


title: METSIM1924

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)


title: H3K4me2_0.4yr

tag: tissue

tag: age

tag: antibody


title: METSIM1921

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM1896

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)


title: METSIM2044

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM1915

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)


title: Long Stationary Rep3 (35)

tag: development stage

tag: strain

tag: rna fraction

tag: treatment

tag: fragmentation

tag: selected insert size


title: Long Exponential Rep1 (30)


title: METSIM1891

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)


title: METSIM1892

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: log10 insulin area under the curve above basal (ogtt) (pmol/l * min)

tag: log10 matsuda insulin sensitivity index

tag: muscle mass (%)

tag: lg10 serum c-reactive protein (mg/l)

tag: lg10 plasma adiponectin (mg/l)

tag: ogtt fasting plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma insulin (mu/l)

tag: log10 ogtt fasting plasma proinsulin (pm/l)

tag: ogtt 30 min plasma proinsulin (pm/l)

tag: ogtt 120 min plasma proinsulin (pm/l)

tag: log10 bioimpedance

tag: log10 bioimpedance (reactance)

tag: waist to hip ratio

tag: log10 serum bilirubin (umol/l)

tag: log10 serum alanine aminotransfrase (u/l)

tag: log10 creatinine (umol/l)


title: METSIM1784

tag: age

tag: tissue

tag: log10 body mass index

tag: log10 basal metabolic rate (kcal)

tag: log2 estimated glomerular filtration rate using modification of diet in renal disease (egfr_mdrd)

tag: log10 estimated creatinine clearance rate using cockfcrot-gault formulaa (egcr)

tag: plasma free fatty acids under the curve ogtt (mmol/l * min)

tag: fat mass (%)

tag: log10 plasma glucose area under the curve (ogtt) (mmol/l * min)

tag: plasma glucose area under the curve above basal (ogtt) (mmol/l * min)

tag: log10 homair (insulin resistance index based on homa)

tag: log10 homais (insulin secretion index based on homa)

tag: log10 insulin area under the curve (ogtt) (pmol/l * min)

tag: insgenin (insulinogenic index)

tag: ogtt 30 min plasma free fatty acid (mmol/l)

tag: ogtt 120 min plasma free fatty acid (mmol/l)

tag: ogtt fasting plasma glucose (mmol/l)

tag: ogtt 30 min plasma glucose (mmol/l)

tag: ogtt 120 min plasma glucose (mmol/l)

tag: log10 il1 receptor antagonist (pg/ml)

tag: log10 il1 beta (pg/ml)

tag: log10 ogtt fasting plasma insulin (mu/l)

tag: ogtt 30 min plasma insulin (mu/l)

tag: log10 total cholesterol (mmol/l)

tag: log10 ldl cholesterol (mmol/l)

tag: log10 hdl cholesterol (mmol/l)

tag: log10 total triglycerides (mmol/l)

tag: log10 serum apoa1 (g/l)

tag: log10 serum apob (g/l)

tag: log10 urinary albumin excretion rate (ug/min)