title: SG11474142_252665248208_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_31Day 600


title: SG11474142_252665240351_S001_GE1_1105_Oct12_1_1

status: Public on Mar 30 2020

type: RNA

city: Borstel/Suelfeld

first: Maja

last: Reimann

state: Schleswig Holstein

address: Parkallee 35

department: Clinical infectious disease

country: Germany

institute: Research Center Borstel

description: Romanian MDR Cohort

hyb_protocol: Agilent Low Input Quick Amp Labelling Kit One Color according to manufacturers instructions

data_processing: Data has been log-transformed and normalized (percentile shift) within the Agilent GeneSpring V13 software

molecule: total RNA

organism: Homo sapiens

source_name: Pat_RVC_32Day 0

extract_protocol: Paxgene blood RNA isolation kit according to manufacturers instructions

treatment_protocol: Whole-blood samples were stored using PAX gene tubes

tag: disease state

value: MDR

tag: tissue

value: whole-blood


title: SG11474142_252665248193_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

scan_protocol: Agilent Low Input Quick Amp Labelling Kit One Color according to manufacturers instructions

source_name: Pat_RVC_31Day 450


title: SG11474142_252665248193_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_31Day 180

label_protocol: Agilent Low Input Quick Amp Labelling Kit One Color according to manufacturers instructions


title: SG11474142_252665240382_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_31Day 14


title: BC1621

city: Kanagawa

first: Satoko

last: Takizawa

address: kamakurashi

country: Japan

institute: Toray industries inc

description:
SH4YJ36_Cell4
miRNA

hyb_protocol: Hybridized for 16 h at 32 ºC with rotary shaker (250 rpm). Hybridization buffer and washing protocol was attached in the 3D-Gene® miRNA oligo chip kit.

scan_protocol: 3D-Gene® Scanner (Toray Industries, Inc.) was used for scanning. Images were quantified using Extraction version 2.0.0.6 (Toray Industries, Inc.).

data_processing: The presence of miRNA was determined based on a corresponding microarray signal of greater than [the mean + 2 × standard deviation] of the negative controls signal, of which the top and bottom ranked ones by signal intensity were removed. Once a miRNA was considered present, the mean signal of the negative controls of which the top and bottom 5% ranked by signal intensity were removed was subtracted from the miRNA signal. When the signal value was negative (or undetEsophageal Cancerted) after background subtraction, the value was replaced by 0.1 on a base 2 logarithm scale.

source_name: Serum

label_protocol: miRNA was labeled using 3D-Gene® miRNA Labeling kit in accordance with the manufacturer's instructions.

extract_protocol: Total RNA was extracted each from 300uL serum samples using 3D-Gene® RNA extraction reagent from liquid sample kit (Toray Industries, Inc.).

value: Non-cancer control

tag: Sex

value: Female

tag: age

value: serum


title: SG11474142_252665248212_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_32Day 300


title: BC1453

description:
SH4YM06_Cell4
miRNA


title: BC1509

description:
SH4YL60_Cell4
miRNA


title: SG11474142_252665240382_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_31Day 0


title: SG11474142_252665248212_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_32Day 180


title: BC1451

description:
SH4YM06_Cell2
miRNA


title: BC1448

description:
SH4YM05_Cell3
miRNA


title: SG11474142_252665240382_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_31Day 28


title: SG11474142_252665241155_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_30Day 14


title: BC1445

description:
SH4YM03_Cell4
miRNA


title: SG11474142_252665240762_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_30Day 180


title: SG11474142_252665248311_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_30Day 600


title: BC1433

description:
SH4YL60_Cell3
miRNA


title: BC1366

description:
SH4YH01_Cell1
miRNA


title: BC1348

description:
SH4YL58_Cell2
miRNA


title: SG11474142_252665248193_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_31Day 300


title: BC1305

description:
SH4YE30_Cell4
miRNA


title: BC1299

description:
SH4YE29_Cell2
miRNA


title: SG11474142_252665240761_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_30Day 300


title: BC1347

description:
SH4YE51_Cell2
miRNA


title: BC1587

description:
SH4YJ26_Cell2
miRNA


title: SG11474142_252665241153_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort


title: SG11474142_252665241154_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_30Day 0


title: SG11474142_252665248206_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 600


title: BC1284

description:
SH4YL52_Cell4
miRNA


title: BC1269

description:
SH4YD55_Cell4
miRNA


title: SG11474142_252665248205_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 180


title: SG11474142_252665241164_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 28


title: SG11474142_252665241155_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_30Day 28


title: SG11474142_252665248206_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 450


title: BC1123

description:
SH4YC30_Cell2
miRNA


title: BC1110

description:
SH4YC27_Cell1
miRNA


title: SG11474142_252665248211_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 450


title: BC1253

description:
SH4YD52_Cell4
miRNA

source_name: Serum


title: SG11474142_252665240654_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 0


title: BC1164

description:
SH4YD19_Cell3
miRNA


title: SG11474142_252665248211_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 600


title: BC1094

description:
SH4YC21_Cell1
miRNA


title: BC1111

description:
SH4YC27_Cell2
miRNA


title: BC1154

description:
SH4YD12_Cell1
miRNA


title: BC1089

description:
SH4YC15_Cell4
miRNA


title: SG11474142_252665248211_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 180


title: SG11474142_252665248211_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 300


title: SG11474142_252665240654_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 28


title: SG11474142_252665240653_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 14


title: SG11474142_252665240762_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 14


title: BC0977

description:
SH4Y451_Cell4
miRNA


title: SG11474142_252665248206_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_29Day 300


title: BC1053

description:
SH4YC02_Cell4
miRNA


title: BC0963

description:
SH4Y448_Cell2
miRNA


title: Patient479_Baseline

type: SRA

city: Cincinnati

first: Mario

last: Medvedovic

state: OH

address: 3223 Eden Av. ML 56

department: Department of Environmental Health

country: USA

institute: University of Cincinnati

description:
NL9
countsTable2.xls

library_source: transcriptomic

data_processing:
bcl files were demultiplexed and converted to fastq files using bcl2fastq
fastq seqences were aligned to hg19 using Tophat
number of reads was calculated for each Entrez gene
differential expression analysis was performed using edgeR
Genome_build: hg19
Supplementary_files_format_and_content: tab delimited raw counts with genes in rows and samples in columns

source_name: neuroblastoma patient without TMA

extract_protocol: RNA libraries were prepared for sequencing using standard Illumina protocols

value: PBMC


title: BC0962

description:
SH4Y448_Cell1
miRNA


title: BC0921

description:
SH4YL41_Cell4
miRNA


title: SG11474142_252665240350_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_27Day 180


title: Patient451_Recovery

description:
NL17
countsTable2.xls


title: SG11474142_252665248310_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_27Day 300


title: SG11474142_252665241168_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_28Day 0


title: BC0973

description:
SH4YL42_Cell3
miRNA


title: SG11474142_252665241154_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_27Day 28


title: SG11474142_252665248307_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_26Day 450


title: SG11474142_252665241154_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_27Day 0


title: Patient451_Baseline

description:
NL15
countsTable2.xls


title: Patient163_LowALC_TMA_timepoint

description:
NL13
countsTable2.xls


title: BC0983

description:
SH4Y453_Cell2
miRNA


title: Patient451_LowALC_TMA_timepoint

description:
NL16
countsTable2.xls


title: Patient163_Recovery

description:
NL14
countsTable2.xls


title: Patient163_Baseline

description:
NL12
countsTable2.xls


title: SG11474142_252665248312_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_25Day NA


title: SG11474142_252665248312_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_25Day 180


title: Patient479_Recovery

description:
NL11
countsTable2.xls


title: Patient479_LowALC_TMA_timepoint

description:
NL10
countsTable2.xls


title: SG11474142_252665240652_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_25Day 14


title: SG11474142_252665240384_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_25Day 0


title: UPN413_TMA

description:
SD8
countsTable1.xls

source_name: neuroblastoma patient with TMA


title: UPN413_Baseline

description:
SD7
countsTable1.xls


title: SG11474142_252665240652_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_25Day 28


title: SG11474142_252665248202_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_24Day 450


title: SG11474142_252665248202_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_24Day 600


title: UPN405_TMA

description:
SD5
countsTable1.xls


title: UPN405_TMAresolution

description:
SD6
countsTable1.xls


title: SG11474142_252665248202_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_24Day 300


title: SG11474142_252665241157_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_24Day 180


title: SG11474142_252665241154_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_27Day 14


title: UPN443_TMAresolution

description:
SD3
countsTable1.xls


title: SG11474142_252665248307_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_26Day 600


title: SG11474142_252665241157_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_24Day 28


title: UPN443_TMA

description:
SD2
countsTable1.xls


title: SG11474142_252665240687_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_24Day 14


title: UPN443_Baseline

description:
SD1
countsTable1.xls


title: SG11474142_252665248311_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_23Day 450


title: UPN405_Baseline

description:
SD14
countsTable1.xls


title: UPN140_TMA

description:
SD15
countsTable1.xls


title: UPN140_Baseline

description:
SD10
countsTable1.xls


title: SG11474142_252665240687_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort


title: SG11474142_252665240384_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_23Day 180


title: SG11474142_252665240384_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_23Day 28


title: UPN413_TMAresolution

description:
SD9
countsTable1.xls


title: SG11474142_252665240384_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_23Day 14


title: SG11474142_252665240383_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_23Day 0


title: SG11474142_252665240761_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_23Day 300


title: SG11474142_252665248199_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_22Day 450


title: SG11474142_252665240350_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_22Day 14


title: SG11474142_252665241156_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_21Day 28


title: SG11474142_252665241158_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_21Day 180


title: SG11474142_252665241156_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_21Day 14


title: SG11474142_252665241156_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_21Day 0


title: SUM159RJQ1

city: Boston

first: Kornelia

last: Polyak

state: MA

address: 450 Brookline Ave

department: Medical Oncology

institute: Dana-Farber Cancer Institute

data_processing:
Single-cell RNA-seq data generated by 10x genomics are preprocessed using the Cell Ranger (https://www.10xgenomics.com/) to obtain the UMI (unique molecular identifier) counts for each gene in each indexed cell type.
To get a reliable single cell transcriptome dataset, we exclude the cells with less than 200 genes expressed (UMI > 0) or the cells with more than 80% UMIs from mitochondrial genes. The filtered data is then normalized and scaled by using Seurat to remove unwanted source of variations {Lun, 2016 #8526}.
Read 1 (R1) has a length of 26 bases corresponding to the 10x cell barcode's 16 bases, followed by the UMI's 10 bases. Read 2 (R2) has a length of 98 bases corresponding to biological RNA. Index 1 (I1) contains the sample index sequence information that is incorporated into the i7 index read (8-bp).
Genome_build: GRCh38
Supplementary_files_format_and_content: Rdata contains the raw UMI counts in gene level

source_name: breast cancer cells

growth_protocol: SUM149, SUM159, SUM149R, SUM159R cells were grown in SUM Medium

extract_protocol:
Cells were collected by trypsinization and processed according to the 10xGenomics sample preparation protocol (Chromium Single Cell 3’ v2 Reagent Kit, 10xGenomics).
Libraries were constructed according to the 10xGenomics sample preparation protocol (Chromium Single Cell 3’ v2 Reagent Kit, 10xGenomics).

treatment_protocol: SUM149, SUM159, SUM149R, SUM159R cells were incubated for 12 hr with JQ1 or DMSO treatment.

tag: cell line

tag: treatment

tag: index


title: SG11474142_252665240381_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_20Day 28


title: UPN140_TMAresolution

description:
SD17
countsTable1.xls

source_name: neuroblastoma patient with TMA


title: SUM159RDMSO

value: DMSO


title: SUM159DMSO


title: SUM159JQ1


title: SG11474142_252665240381_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_20Day 14


title: SG11474142_252665241153_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_20Day 300


title: SG11474142_252665248307_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_19Day 600


title: SUM149JQ1


title: SUM149RJQ1


title: SUM149DMSO


title: SG11474142_252665248307_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_19Day 450


title: SG11474142_252665240687_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_19Day 28


title: SG11474142_252665240687_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_19Day 180


title: SG11474142_252665241163_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_18Day 14


title: SG11474142_252665241163_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_19Day 14


title: SG11474142_252665241163_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_18Day NA


title: SG11474142_252665248208_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_22Day 600


title: SG11474142_252665241163_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_18Day 28


title: SG11474142_252665240350_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_19Day 0


title: SG11474142_252665241168_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_22Day 0


title: SG11474142_252665241157_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_18Day 0


title: SG11474142_252665240640_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_17Day 14


title: SG11474142_252665241164_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_20Day 180


title: SG11474142_252665240640_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_17Day 0


title: SG11474142_252665240353_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_16Day 14


title: SG11474142_252665240640_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_16Day 28


title: SG11474142_252665240349_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_15Day 28


title: SG11474142_252665240350_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_15Day 180


title: SG11474142_252665241167_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_15Day 0


title: SG11474142_252665241157_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_15Day 14


title: SG11474142_252665241166_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_15Day 300


title: SG11474142_252665241160_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_14Day 0


title: SG11474142_252665241161_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_14Day 180


title: SUM149RDMSO

source_name: breast cancer cells


title: SG11474142_252665241153_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_14Day 300


title: SG11474142_252665248203_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 450


title: SG11474142_252665248203_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 600


title: SG11474142_252665240762_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 0


title: SG11474142_252665248209_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_12Day 300


title: SG11474142_252665248202_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 180


title: SG11474142_252665240381_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 28


title: SG11474142_252665248210_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_12Day 600


title: SG11474142_252665248209_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_12Day 450


title: SG11474142_252665248203_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 300


title: SG11474142_252665240381_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_13Day 14


title: SG11474142_252665240380_S001_GE1_1105_Oct12_1_3

description: Romanian MDR Cohort

source_name: Pat_RVC_12Day 28


title: SG11474142_252665241164_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_12Day 14


title: SG11474142_252665248216_S001_GE1_1105_Oct12_1_1

description: Romanian MDR Cohort

source_name: Pat_RVC_11Day 450


title: SG11474142_252665248215_S001_GE1_1105_Oct12_1_4

description: Romanian MDR Cohort

source_name: Pat_RVC_11Day 180


title: SG11474142_252665248216_S001_GE1_1105_Oct12_1_2

description: Romanian MDR Cohort

source_name: Pat_RVC_11Day 600


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description: Romanian MDR Cohort

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description: Romanian MDR Cohort

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description: Romanian MDR Cohort

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description: Romanian MDR Cohort

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description: Romanian MDR Cohort

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description: Romanian MDR Cohort

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description: Romanian MDR Cohort

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description: Identification cohort

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description: Identification cohort

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description: Identification cohort

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description: Identification cohort

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title: SG11474142_252665222390_S001_GE1_1105_Oct12_1_3

description: Identification cohort

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title: SG11474142_252665231920_S001_GE1_1105_Oct12_1_1

description: Identification cohort

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description: Identification cohort

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description: Identification cohort

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title: SG11474142_252665226307_S001_GE1_1105_Oct12_1_3

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description: Identification cohort

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description: Identification cohort

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description: Identification cohort

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title: SG11474142_252665228412_S001_GE1_1105_Oct12_1_3

description: Identification cohort

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title: SG11474142_252665228412_S001_GE1_1105_Oct12_1_1

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title: Raji/253R  [OT12]

city: La Jolla

first: Stephen

middle: B

last: Howell

state: CA

address: 3855 Health Sciences Drive, #0819, Room 3344

department: School of Medicine and Moores Cancer Center

institute: University of California, San Diego

description:
OT12_S6
Raji.resistant.c

data_processing:
The FASTQ files were downloaded from UCSD and the overall quality of the data was assessed first by quality score distribution, read base distribution and sequence overrepresentation using FastQC v0.11.4  was assessed first by quality score distribution, read base distribution and sequence overrepresentation using  FastQC v0.11.4
The reads were aligned to the human genome build 37 using SubRead v1.5.0-p1  were aligned to the human genome build 37 using SubRead v1.5.0-p1
The featureCounts v1.5.0-p1 program was used to counts reads relative  to Ensembl 75 gene models with respect to strandedness.
A multi dimensional scaling (MDS) plot using the edgeR package was generated.  package was generated.
Trimmed mean of M saling normalization factors were computed and used with the voom approach. Empirical Bayes approach implemented by limma was used to fit a linear model contrasting Raji and Raji/253R samples. The p-values were adjusted using the false discovery rate method of Benjamin and Hochberg. Genes were considered to be differentially expressed if their adjusted p-value was less than 0.05 level and their fold change was greater than 2 in either direction.
Genome_build: human genome build 37
Supplementary_files_format_and_content: bigWig files and an excel file (with mu.tiple spreadsheets) of expression summary values, fold change expression and p-values were generated.

growth_protocol: The APTO-253-resistant Raji (Raji/253R) cell line was generated by exposure to progressively higher concentrations of APTO-253 over a period of 6 months.

extract_protocol:
Total cellular RNA was isolated using the RNeasy mini kit (QIAGEN, Valencia, CA) from 3 independent samples for each experiment.
RNA libraries were prepared for sequencing using standard Illumina protocols

tag: cell line background

value: Raji

tag: cell type

value: Burkitt lymphoma cell line

tag: genotype/variation

value: APTO-253-resistant Raji (Raji/253R)


title: SG11474142_252665233835_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat55 Day 117


title: SG11474142_252665233835_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat55 Day 14


title: SG11474142_252665226474_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Control11 Day


title: SG11474142_252665226196_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat58 Day 184


title: SG11474142_252665233835_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat55 Day 0


title: Raji [OT08]

description:
OT08_S2
Raji.wildtype.b

source_name: Raji

value: wild type


title: SG11474142_252665233834_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat54 Day 264


title: Raji [OT07]

description:
OT07_S1
Raji.wildtype.a


title: Raji [OT09]

description:
OT09_S3
Raji.wildtype.c


title: SG11474142_252665233834_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat54 Day 453


title: SG11474142_252665226308_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat54 Day 740


title: SG11474142_252665226470_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat54 Day 194


title: SG11474142_252665227485_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat54 Day 25


title: SG11474142_252665226470_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat54 Day 76


title: SG11474142_252665233944_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat53 Day 634


title: SG11474142_252665233944_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat53 Day 306


title: SG11474142_252665233944_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat53 Day 453


title: SG11474142_252665226196_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat53 Day 185


title: SG11474142_252665233835_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat55 Day 20


title: SG11474142_252665226196_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat53 Day 241


title: SG11474142_252665231913_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat52 Day 2


title: SG11474142_252665231913_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat52 Day 246


title: Raji/253R [OT11]

description:
OT11_S5
Raji.resistant.b


title: SG11474142_252665231913_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat52 Day 14


title: SG11474142_252665227490_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat52 Day 93


title: SG11474142_252665227490_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat52 Day 188


title: Raji/253R [OT10]

description:
OT10_S4
Raji.resistant.a


title: SG11474142_252665234426_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat51 Day 12


title: SG11474142_252665234425_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat51 Day 216


title: SG11474142_252665234428_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat51 Day 0


title: SG11474142_252665228449_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat50 Day 14


title: SG11474142_252665226475_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Control10 Day


title: SG11474142_252665233834_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat54 Day 327


title: SG11474142_252665228449_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat50 Day 0


title: SG11474142_252665226424_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat49 Day 74


title: SG11474142_252665222392_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat49 Day 137


title: SG11474142_252665226477_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat49 Day 0


title: SG11474142_252665234425_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat48 Day 7


title: SG11474142_252665227485_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat53 Day 123


title: SG11474142_252665234425_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat48 Day 90


title: SG11474142_252665234429_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat48 Day 41


title: SG11474142_252665234436_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat46 Day 0


title: SG11474142_252665234425_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat48 Day 258


title: SG11474142_252665231913_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat43 Day 29


title: SG11474142_252665234428_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat46 Day 70


title: SG11474142_252665234436_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat47 Day 14


title: SG11474142_252665234428_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat46 Day 10


title: SG11474142_252665231926_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat42 Day 621


title: SG11474142_252665233945_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat43 Day 0


title: SG11474142_252665231998_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat42 Day 290


title: SG11474142_252665233822_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat45 Day 0


title: SG11474142_252665231998_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat42 Day 423


title: SG11474142_252665233945_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat43 Day 14


title: SG11474142_252665233834_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat41 Day 622


title: SG11474142_252665228420_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat44 Day 124


title: SG11474142_252665233822_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat42 Day 54


title: SG11474142_252665231921_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat42 Day 97


title: SG11474142_252665222392_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat49 Day 244


title: SG11474142_252665226197_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat41 Day 187


title: SG11474142_252665233833_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat41 Day 306


title: SG11474142_252665226477_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat49 Day 14


title: SG11474142_252665233833_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat41 Day 475


title: SG11474142_252665226197_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat41 Day 201


title: SG11474142_252665227486_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat41 Day 14


title: SG11474142_252665227486_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat41 Day 230


title: SG11474142_252665226195_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat40 Day


title: SG11474142_252665227487_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat41 Day 0


title: SG11474142_252665227484_S001_GE1_1105_Oct12_1_2

description: Identification cohort


title: SG11474142_252665231924_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat39 Day 312


title: SG11474142_252665226195_S001_GE1_1105_Oct12_1_1

description: Identification cohort


title: SG11474142_252665231924_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat39 Day 206


title: SG11474142_252665228446_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat38 Day


title: SG11474142_252665228446_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat38 Day 14


title: SG11474142_252665231924_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat39 Day 261


title: SG11474142_252665228446_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat38 Day 0


title: SG11474142_252665231914_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat37 Day 112


title: SG11474142_252665231915_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat37 Day 14


title: SG11474142_252665231915_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat37 Day 0


title: SG11474142_252665226476_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Control8 Day


title: SG11474142_252665231919_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat36 Day 29


title: SG11474142_252665231919_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat36 Day 0


title: SG11474142_252665231919_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat36 Day 14


title: SG11474142_252665222391_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat35 Day 108


title: SG11474142_252665226478_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat35 Day 40


title: SG11474142_252665227487_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat35 Day 14


title: SG11474142_252665222391_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat35 Day 206


title: SG11474142_252665227487_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat35 Day 0


title: SG11474142_252665234437_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat34 Day 381


title: SG11474142_252665226308_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Control9 Day


title: SG11474142_252665226476_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Control7 Day


title: SG11474142_252665228450_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat34 Day 49


title: SG11474142_252665228450_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat34 Day 14


title: SG11474142_252665227484_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat40 Day


title: SG11474142_252665228418_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat34 Day 0


title: SG11474142_252665228413_S001_GE1_1105_Oct12_1_4

description: Identification cohort


title: SG11474142_252665226198_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat33 Day


title: SG11474142_252665231914_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat37 Day 127


title: SG11474142_252665226305_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat33 Day 0


title: SG11474142_252665231921_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat32 Day 99


title: SG11474142_252665226306_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat32 Day 14


title: SG11474142_252665226306_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat32 Day 0


title: SG11474142_252665226304_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat31 Day 24


title: SG11474142_252665231921_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat32 Day 29


title: SG11474142_252665226305_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat31 Day 14


title: SG11474142_252665226304_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat31 Day 187


title: SG11474142_252665226305_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat31 Day 0


title: SG11474142_252665226476_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Control6 Day


title: SG11474142_252665234436_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat30 Day 64


title: SG11474142_252665228420_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat30 Day 268


title: SG11474142_252665226475_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Control5 Day


title: SG11474142_252665231904_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat29 Day 14


title: SG11474142_252665222391_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat28 Day 224


title: SG11474142_252665226424_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat28 Day 30


title: SG11474142_252665222391_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat28 Day 142


title: SG11474142_252665227485_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat28 Day 0


title: SG11474142_252665227484_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat28 Day 14


title: SG11474142_252665231925_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat27 Day 316


title: SG11474142_252665231925_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat27 Day 470


title: SG11474142_252665226198_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat33 Day


title: SG11474142_252665231925_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat27 Day 56


title: Plate2D_62

city: New York

first: Yu-Jui

last: Ho

state: New York

address: 417 E 68th St

department: Cancer Biology & Genetics Program

institute: Memorial Sloan Kettering Cancer Center

data_processing:
Adapter removal and removing reads shorter than 36bp using Bbduk
Align reads to reference genome mm9 using Kallisto and obtain read count tables
Genome_build: mm9
Supplementary_files_format_and_content: read count table

organism: Mus musculus

source_name: KPC1199EGFP Adherent cells at passage 9

growth_protocol: KPC1199-EGFP cells were thawed and passaged in DMEM supplemented with 10% Fetal Bovine Serum, 1% Pencillin/streptomycin

extract_protocol:
Trypsinzed to create suspension of adherent cells
Single cells were isolated and cDNA amplified on medium sized IFC from Fluidigm on the C1 system following the manufacturer's instructions. Library was constucted using nextera XT kit again following the guildlines from Fluidigm

treatment_protocol: No treatment

tag: strain background

value: Pancreatic cancer

value: EGFP expression


title: SG11474142_252665234438_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat26 Day 354


title: SG11474142_252665226477_S001_GE1_1105_Oct12_1_2

description: Identification cohort


title: Plate2D_61


title: SG11474142_252665234438_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat26 Day 82


title: SG11474142_252665234438_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat26 Day 10


title: SG11474142_252665234438_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat26 Day 192


title: Plate2D_60


title: Plate2D_59


title: Plate2D_58


title: SG11474142_252665233833_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat25 Day 176


title: Plate2D_57


title: SG11474142_252665233832_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat25 Day 0


title: SG11474142_252665231904_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat29 Day 259


title: SG11474142_252665233833_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat25 Day 7


title: SG11474142_252665232001_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat24 Day 182


title: Plate2D_55


title: SG11474142_252665231904_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat29 Day 0


title: Plate2D_56


title: SG11474142_252665232001_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat24 Day 9


title: Plate2D_54


title: SG11474142_252665232001_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat24 Day 14


title: SG11474142_252665231925_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat27 Day 588


title: SG11474142_252665231918_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat23 Day 339


title: SG11474142_252665232001_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat24 Day 0


title: Plate2D_51


title: Plate2D_53


title: Plate2D_52


title: Plate2D_50


title: SG11474142_252665231918_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat23 Day 704


title: SG11474142_252665231918_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat23 Day 593


title: Plate2D_49

source_name: KPC1199EGFP Adherent cells at passage 9


title: Plate2D_48


title: SG11474142_252665231919_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat23 Day 291


title: SG11474142_252665231918_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat23 Day 445


title: SG11474142_252665226473_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat23 Day 200


title: Plate2D_45


title: Plate2D_44


title: Plate2D_46


title: SG11474142_252665228448_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat22 Day 0


title: Plate2D_47


title: SG11474142_252665228447_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat22 Day 14


title: Plate2D_42


title: Plate2D_43


title: SG11474142_252665226473_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat23 Day 229


title: SG11474142_252665233806_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat21 Day 187


title: SG11474142_252665233806_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat21 Day 132


title: SG11474142_252665233806_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat21 Day 14


title: Plate2D_39


title: Plate2D_38


title: SG11474142_252665231926_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat20 Day 621


title: Plate2D_37


title: SG11474142_252665227481_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat20 Day 0


title: SG11474142_252665226470_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat20 Day 76


title: SG11474142_252665226470_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat20 Day 195


title: SG11474142_252665231926_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat20 Day 466


title: Plate2D_36


title: Plate2D_40


title: Plate2D_35


title: Plate2D_34


title: Plate2D_33


title: SG11474142_252665234428_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat22 Day 188


title: SG11474142_252665231926_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat20 Day


title: SG11474142_252665227481_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat20 Day 14


title: Plate2D_32

source_name: KPC1199EGFP Adherent cells at passage 9


title: Plate2D_41


title: SG11474142_252665233819_S002-2_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat19 Day 8


title: SG11474142_252665233819_S002-2_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat19 Day 120


title: Plate2D_28


title: Plate2D_29


title: SG11474142_252665234437_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat18 Day 711


title: SG11474142_252665233819_S002-2_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat19 Day 15


title: Plate2D_27


title: SG11474142_252665231915_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat18 Day 323


title: Plate2D_26


title: SG11474142_252665231915_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat18 Day 255


title: Plate2D_25


title: Plate2D_24


title: SG11474142_252665228421_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat18 Day 74


title: Plate2D_22


title: SG11474142_252665228422_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat18 Day 14


title: Plate2D_21


title: Plate2D_20


title: SG11474142_252665226473_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat17 Day 235


title: Plate2D_23


title: SG11474142_252665227491_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat16 Day 81


title: Plate2D_19


title: Plate2D_18


title: SG11474142_252665233806_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat19 Day 203


title: SG11474142_252665226304_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat16 Day 14


title: Plate2D_30


title: Plate2D_17


title: Plate2D_31


title: SG11474142_252665226304_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat16 Day 0


title: Plate2D_15


title: Plate2D_16


title: SG11474142_252665231999_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat15 Day 617


title: SG11474142_252665231999_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat15 Day 469


title: Plate2D_14


title: Plate2D_13


title: Plate2D_12


title: SG11474142_252665226473_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat17 Day 83


title: SG11474142_252665226195_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat15 Day 217


title: SG11474142_252665227491_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat16 Day 221


title: SG11474142_252665227483_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat15 Day 14


title: SG11474142_252665226195_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat15 Day 126


title: SG11474142_252665227483_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat15 Day 51


title: Plate2D_11

source_name: KPC1199EGFP Adherent cells at passage 9


title: Plate2D_10


title: Plate2D_9


title: Plate2D_8


title: Plate2D_7


title: SG11474142_252665231999_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat14 Day 599


title: SG11474142_252665227488_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat16 Day 18


title: SG11474142_252665227484_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat15 Day 0


title: SG11474142_252665227486_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat13 Day 12


title: Plate2D_5


title: SG11474142_252665233832_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat13 Day 493


title: SG11474142_252665226474_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Control4 Day


title: Plate2D_6


title: Plate2D_4


title: SG11474142_252665233832_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat13 Day 454


title: Plate2D_3


title: SG11474142_252665233832_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat13 Day 312


title: SG11474142_252665226424_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat13 Day 192


title: SG11474142_252665231999_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat15 Day 336


title: SG11474142_252665226424_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat13 Day 86


title: Plate2D_2


title: Mouse3_GFPSpleenMet_S47_clean

data_processing:
library strategy: GTO sequencing
Adapter removal and removing reads shorter than 36bp using Bbduk
Map reads to mm9 genome using STAR aligner
Separate aligned reads into exonic and allnonexonic
Realign exonic reads to reference genome mm9 using Kallisto and obtain read count tables
Realign allnonexonic reads to refenrence genome mm9 using Bowtie 1.0, remove PCR duplicate reads and process for CNV analysis
Genome_build: mm9
Supplementary_files_format_and_content: read count tables for RNAseq section of data, Varbin files with bincounts for DNAseq section

source_name: Mouse3_Spleen Metastasis

extract_protocol:
Primary tumors were dissociated using collagenase D and trypsin. They were treated with ACK lysis buffer to remove contaminating red blood cells. These dissociated cells were stained with EpCam, CD45 antibodies. Single cells were isolated by flow cytometry for GFP+, EpCAM+, GFP+EpCAM+ and CD45+ from primary tumors. GFP+ cells were isolated from various metastases
Single cells isolated into 10x Lysis Buffer with Rnase inhibitor. Next they were processed for mRNA transcription for first strand synthesis using Oligo-dT primer and cDNA generated is amplified for 15 cycles following SMART-Seq2 PCR primers. Samples were then treated ionically to fragment gDNA and cDNA to 400-700bp fragments. Later gDNA was amplified using SeqXE kit from Sigma Aldirch using manufacturer instructions. resulting cDNA and gDNA fragments are quantified.  Following this, libraries for sequencing were prepared by subjecting the 1ug of gDNA and cDNA fragments to end-repair, 3′ adenylation and ligation of TruSeq barcoded adapters. After ligation, DNA fragments were size selected using Ampure XP beads. A 0.75 ratio of beads to sample was used to select fragments larger than 200bp and avoid adapter dimers. These fragments were further amplified by PCR, cleaned using Qiaquick PCR Purification Kit and then once again size selected using Ampure XP beads with a 0.75 ratio of beads to sample. The final libraries were then quantified on Nanodrop and Bioanalyzer using Agilent's High Sensitivity DNA Analysis Kit. 10nM of each sample was then pooled together and the resulting pool was then sequenced single read 76bp length on the Illumina NextSeq

treatment_protocol: 50000 KPC1199-EGFP cells in matrigel were injected orthotopically into the pancreas of 6-8 week old C57BL/6 male mice. Tumors were allowed to grow for 6-8 weeks before tumors were extracted.

tag: strain

value: male

tag: tumor type

value: Metastasis

value: Spleen

value: Tumor

tag: marker

value: GFP, Calcien Violet for Live/Dead

tag: molecule type

value: genomic DNA and mRNA


title: Mouse3_GFPSpleenMet_S48_clean


title: SG11474142_252665231920_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat12 Day 21

value: MDR

value: whole-blood


title: SG11474142_252665226308_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Control3 Day


title: Mouse3_GFPSpleenMet_S46_clean


title: SG11474142_252665231905_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat11 Day 607


title: SG11474142_252665231923_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat11 Day 455


title: Mouse3_GFPSpleenMet_S45_clean


title: Mouse3_GFPSpleenMet_S44_clean


title: SG11474142_252665231923_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat11 Day 305


title: Mouse3_GFPSpleenMet_S43_clean


title: SG11474142_252665227490_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat11 Day 235


title: Mouse3_GFPSpleenMet_S42_clean


title: Mouse3_GFPSpleenMet_S41_clean


title: SG11474142_252665227490_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat11 Day 83


title: SG11474142_252665227482_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat11 Day 14


title: SG11474142_252665228421_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat11 Day 0


title: Mouse3_GFPSpleenMet_S40_clean


title: SG11474142_252665231905_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat10 Day 635


title: Plate2D_1

source_name: KPC1199EGFP Adherent cells at passage 9


title: Mouse3_GFPSpleenMet_S35_clean


title: Mouse3_GFPSpleenMet_S36_clean


title: Mouse3_GFPSpleenMet_S34_clean


title: SG11474142_252665231905_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat10 Day 320


title: SG11474142_252665231905_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat10 Day 484


title: SG11474142_252665228448_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat9 Day 201


title: Mouse3_GFPSpleenMet_S33_clean


title: SG11474142_252665228418_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat8 Day 102


title: SG11474142_252665228418_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat8 Day 14


title: SG11474142_252665228418_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat8 Day 0


title: Mouse3_GFPSpleenMet_S28_clean

source_name: Mouse3_Spleen Metastasis


title: SG11474142_252665233807_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat7 Day 4


title: Mouse3_GFPSpleenMet_S26_clean


title: Mouse3_GFPSpleenMet_S29_clean


title: SG11474142_252665234427_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat7 Day 33


title: SG11474142_252665233807_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat7 Day 14


title: Mouse3_GFPPrimary_S41_clean

source_name: Mouse3_Primary Pancreatic Tumor

value: Primary

value: Pancreas


title: SG11474142_252665228449_S001_GE1_1105_Oct12_1_1

description: Identification cohort

value: non MDR


title: Mouse3_GFPPrimary_S40_clean


title: SG11474142_252665228450_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat7 Day 0


title: Mouse3_GFPSpleenMet_S25_clean


title: SG11474142_252665226474_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Control2 Day

value: Healthy Controls


title: Mouse3_GFPPrimary_S39_clean


title: SG11474142_252665228447_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat6 Day 28


title: SG11474142_252665228447_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat6 Day 14


title: Mouse3_GFPPrimary_S38_clean


title: Mouse3_GFPPrimary_S37_clean


title: Mouse3_GFPPrimary_S36_clean


title: SG11474142_252665228447_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat6 Day 0


title: Mouse3_GFPPrimary_S35_clean


title: Mouse3_GFPPrimary_S31_clean


title: Mouse3_GFPSpleenMet_S31_clean


title: SG11474142_252665228419_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat5 Day 92


title: Mouse3_GFPSpleenMet_S30_clean


title: Mouse3_GFPPrimary_S32_clean


title: Mouse3_GFPPrimary_S30_clean


title: SG11474142_252665222390_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat4 Day 385


title: Mouse3_GFPPrimary_S29_clean


title: SG11474142_252665222390_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat4 Day 210


title: SG11474142_252665228446_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat7 Day 181


title: Mouse3_GFPPrimary_S28_clean


title: SG11474142_252665226478_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat4 Day 119


title: Mouse3_GFPPrimary_S27_clean


title: Mouse3_GFPSpleenMet_S32_clean


title: SG11474142_252665226307_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat4 Day 0


title: Mouse3_GFPPrimary_S26_clean


title: SG11474142_252665228450_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat3 Day 0


title: Mouse3_GFPPrimary_S25_clean


title: SG11474142_252665234423_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat2 Day 108


title: Mouse3_GFPPrimary_S21_clean


title: SG11474142_252665234423_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat2 Day 57


title: Mouse3_GFPPrimary_S20_clean


title: SG11474142_252665234424_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Pat2 Day 0


title: Mouse3_GFPPrimary_S18_clean


title: SG11474142_252665231920_S001_GE1_1105_Oct12_1_3

description: Identification cohort

source_name: Pat5 Day 77


title: Mouse3_GFPPrimary_S19_clean

source_name: Mouse3_Primary Pancreatic Tumor


title: SG11474142_252665234427_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat1 Day 1


title: Mouse3_GFPPrimary_S15_clean


title: Mouse3_GFPPrimary_S16_clean


title: SG11474142_252665233807_S001_GE1_1105_Oct12_1_1

description: Identification cohort

source_name: Pat1 Day 68


title: SG11474142_252665247083_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_60 Day 180


title: SG11474142_252665248005_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_60 Day 105


title: Mouse3_GFPPrimary_S10_clean


title: Mouse3_GFPPrimary_S09_clean


title: SG11474142_252665247083_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_60 Day 470


title: SG11474142_252665247082_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_60 Day 0


title: SG11474142_252665226307_S001_GE1_1105_Oct12_1_2

description: Identification cohort

source_name: Pat4 Day 14


title: Mouse3_GFPPrimary_S08_clean


title: SG11474142_252665248005_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_60 Day 614


title: Mouse3_GFPPrimary_S07_clean


title: SG11474142_252665247082_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_60 Day 14


title: SG11474142_252665248042_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_60 Day 301


title: Mouse3_GFPPrimary_S05_clean


title: SG11474142_252665226308_S001_GE1_1105_Oct12_1_4

description: Identification cohort

source_name: Control1 Day


title: Mouse3_GFPPrimary_S04_clean


title: Mouse3_GFPPeritoneumMet_S96_clean

source_name: Mouse3_Peritoneum Metastasis

value: Peritoneum


title: SG11474142_252665248019_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_59 Day 61


title: SG11474142_252665248020_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_59 Day 616


title: Mouse3_GFPPeritoneumMet_S94_clean


title: Mouse3_GFPPeritoneumMet_S95_clean


title: Mouse3_GFPPeritoneumMet_S93_clean


title: Mouse3_GFPPeritoneumMet_S92_clean


title: SG11474142_252665248019_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_59 Day 33


title: SG11474142_252665248018_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_59 Day 0


title: SG11474142_252665248019_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_59 Day 13


title: SG11474142_252665247083_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_60 Day 26


title: Mouse3_GFPPeritoneumMet_S90_clean


title: SG11474142_252665248044_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_58 Day 20


title: Mouse3_GFPPeritoneumMet_S88_clean


title: Mouse3_GFPPeritoneumMet_S89_clean


title: Mouse3_GFPPeritoneumMet_S91_clean


title: SG11474142_252665248044_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_58 Day 62


title: SG11474142_252665248043_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_58 Day 187


title: SG11474142_252665248044_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_58 Day 484


title: Mouse3_GFPPeritoneumMet_S86_clean


title: Mouse3_GFPPeritoneumMet_S87_clean


title: SG11474142_252665248019_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_59 Day 182


title: Mouse3_GFPPeritoneumMet_S85_clean


title: Mouse3_GFPPrimary_S17_clean

source_name: Mouse3_Primary Pancreatic Tumor


title: Mouse3_GFPPrimary_S06_clean


title: SG11474142_252665248044_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_58 Day 60


title: SG11474142_252665248355_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_57 Day 139

value: Non MDR


title: SG11474142_252665248355_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_57 Day 1


title: SG11474142_252665248355_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_57 Day 61


title: SG11474142_252665248147_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_56 Day 0


title: SG11474142_252665248152_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_56 Day 180


title: Mouse3_GFPPeritoneumMet_S81_clean

source_name: Mouse3_Peritoneum Metastasis


title: Mouse3_GFPPeritoneumMet_S79_clean


title: Mouse3_GFPPeritoneumMet_S77_clean


title: Mouse3_GFPPeritoneumMet_S78_clean


title: Mouse3_GFPPeritoneumMet_S84_clean


title: Mouse3_GFPPeritoneumMet_S76_clean


title: Mouse3_GFPPeritoneumMet_S83_clean


title: SG11474142_252665248147_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_56 Day 15


title: SG11474142_252665247079_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_55 Day 622


title: Mouse3_GFPPeritoneumMet_S74_clean


title: Mouse3_GFPPeritoneumMet_S75_clean


title: SG11474142_252665248041_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_58 Day 13


title: SG11474142_252665246644_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_55 Day 193


title: Mouse3_GFPPeritoneumMet_S73_clean


title: Mouse3_GFPLiverMet_S24_clean

source_name: Mouse3_Liver Metastasis

value: Liver


title: SG11474142_252665247078_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_55 Day 2


title: SG11474142_252665248355_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_57 Day 12


title: SG11474142_252665247078_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_55 Day 80


title: SG11474142_252665247079_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_55 Day 718


title: Mouse3_GFPLiverMet_S21_clean


title: Mouse3_GFPLiverMet_S20_clean


title: Mouse3_GFPLiverMet_S18_clean


title: Mouse3_GFPLiverMet_S12_clean


title: SG11474142_252665248147_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_56 Day 67


title: SG11474142_252665246644_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_55 Day 367


title: Mouse3_GFPLiverMet_S11_clean


title: SG11474142_252665248151_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_55 Day 1083


title: SG11474142_252665246641_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_54 Day 142


title: Mouse3_GFPLiverMet_S09_clean


title: SG11474142_252665248040_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_54 Day 184


title: SG11474142_252665246660_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_54 Day 0


title: SG11474142_252665246641_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_54 Day 156


title: Mouse3_GFPLiverMet_S06_clean


title: Mouse3_GFPLiverMet_S08_clean


title: SG11474142_252665247078_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_55 Day 13


title: SG11474142_252665246660_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_54 Day 13


title: SG11474142_252665246641_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_54 Day 458


title: Mouse3_GFPLiverMet_S02_clean


title: SG11474142_252665247078_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_55 Day 147


title: Mouse3_GFPKidneyMet_S72_clean

source_name: Mouse3_Kidney Metastasis

value: Kidney


title: Mouse3_GFPLiverMet_S01_clean

source_name: Mouse3_Liver Metastasis


title: SG11474142_252665246644_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_54 Day 315


title: SG11474142_252665246642_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_54 Day 603


title: Mouse3_GFPKidneyMet_S71_clean


title: Mouse3_GFPKidneyMet_S70_clean


title: SG11474142_252665248034_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_53 Day 384


title: Mouse3_GFPKidneyMet_S68_clean


title: Mouse3_GFPKidneyMet_S69_clean


title: SG11474142_252665248014_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_53 Day 537


title: Mouse3_GFPLiverMet_S10_clean


title: Mouse3_GFPKidneyMet_S67_clean


title: SG11474142_252665248034_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_53 Day 167


title: SG11474142_252665248034_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_53 Day 0


title: Mouse3_GFPKidneyMet_S65_clean


title: Mouse3_GFPKidneyMet_S66_clean


title: SG11474142_252665248034_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_53 Day 189


title: Mouse3_GFPKidneyMet_S64_clean


title: SG11474142_252665248020_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_52 Day 13


title: SG11474142_252665248020_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_52 Day 57


title: SG11474142_252665248190_S001_GE1_1105_Oct12_1_1


title: Mouse3_GFPKidneyMet_S60_clean


title: Mouse3_GFPKidneyMet_S63_clean


title: Mouse3_GFPPeritoneumMet_S82_clean

source_name: Mouse3_Peritoneum Metastasis


title: Mouse3_GFPKidneyMet_S58_clean


title: Mouse3_GFPKidneyMet_S62_clean


title: Mouse3_GFPKidneyMet_S56_clean


title: SG11474142_252665247080_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_51 Day 63


title: Mouse3_GFPKidneyMet_S54_clean


title: SG11474142_252665248014_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_53 Day 516


title: SG11474142_252665247079_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_51 Day 15


title: Mouse3_GFPKidneyMet_S52_clean


title: Mouse3_GFPKidneyMet_S53_clean


title: SG11474142_252665248005_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_51 Day 182


title: Mouse3_GFPKidneyMet_S51_clean


title: SG11474142_252665248005_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_51 Day 121


title: SG11474142_252665247079_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_51 Day 0


title: SG11474142_252665248026_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_50 Day 14


title: Mouse3_GFPKidneyMet_S50_clean

source_name: Mouse3_Kidney Metastasis


title: SG11474142_252665248020_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_52 Day 0


title: SG11474142_252665248025_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_50 Day 0


title: Mouse3_GFPKidneyMet_S49_clean


title: SG11474142_252665248026_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_50 Day 218


title: SG11474142_252665248021_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_52 Day 365


title: SG11474142_252665248027_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_50 Day 328


title: Mouse3_GFPEpCamPrimary_S61_clean

source_name: Mouse3_Primary Pancreatic Tumor

value: GFP, EpCam, Calcien Violet for Live/Dead


title: Mouse3_GFPEpCamPrimary_S62_clean

value: male


title: Mouse3_GFPEpCamPrimary_S60_clean


title: Mouse3_GFPKidneyMet_S55_clean

value: Metastasis


title: SG11474142_252665248021_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_52 Day 188


title: SG11474142_252665248027_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_50 Day 464


title: SG11474142_252665248026_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_50 Day 148


title: Mouse3_GFPEpCamPrimary_S58_clean


title: Mouse3_GFPEpCamPrimary_S59_clean


title: SG11474142_252665248026_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_50 Day 119


title: SG11474142_252665248010_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_49 Day 644


title: Mouse3_GFPEpCamPrimary_S57_clean


title: Mouse3_GFPEpCamPrimary_S56_clean


title: Mouse3_GFPEpCamPrimary_S55_clean


title: SG11474142_252665248009_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_49 Day 326


title: SG11474142_252665248009_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_49 Day 182


title: Mouse3_GFPEpCamPrimary_S53_clean


title: SG11474142_252665248010_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_49 Day 623


title: SG11474142_252665248038_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_49 Day 0


title: SG11474142_252665248009_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_49 Day 456


title: Mouse3_GFPEpCamPrimary_S54_clean


title: SG11474142_252665248190_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_49 Day 11


title: Mouse3_GFPEpCamPrimary_S52_clean


title: Mouse3_EpCamPrimary_S51_clean

value: EpCam, Calcien Violet for Live/Dead


title: Mouse3_EpCamPrimary_S50_clean

value: Tumor


title: Mouse3_EpCamPrimary_S49_clean


title: Mouse3_EpCamPrimary_S47_clean


title: Mouse3_EpCamPrimary_S48_clean


title: Mouse3_EpCamPrimary_S46_clean


title: Mouse3_EpCamPrimary_S45_clean


title: SG11474142_252665248004_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_48 Day 0


title: SG11474142_252665248006_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_48 Day 181


title: SG11474142_252665248004_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_48 Day 12


title: SG11474142_252665248006_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_48 Day 107


title: SG11474142_252665248009_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_49 Day 82


title: Mouse3_EpCamPrimary_S42_clean

source_name: Mouse3_Primary Pancreatic Tumor


title: SG11474142_252665247085_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_47 Day 308


title: Mouse3_CD45Primary_S82_clean

value: Stromal

value: CD45, Calcien Violet for Live/Dead


title: SG11474142_252665247084_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_47 Day 0

value: MDR


title: Mouse3_CD45Primary_S81_clean

value: genomic DNA and mRNA


title: SG11474142_252665247085_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_47 Day 90

value: whole-blood


title: Mouse3_CD45Primary_S79_clean

value: Primary

value: Pancreas


title: Mouse3_CD45Primary_S80_clean


title: SG11474142_252665247084_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_47 Day 13


title: SG11474142_252665247085_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_47 Day 603


title: Mouse3_CD45Primary_S77_clean


title: SG11474142_252665248014_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_46 Day 0


title: SG11474142_252665248190_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_46 Day 183


title: SG11474142_252665248189_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_46 Day 779


title: SG11474142_252665247085_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_47 Day 441


title: SG11474142_252665248015_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_46 Day 535


title: SG11474142_252665248015_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_46 Day 52


title: Mouse3_CD45Primary_S73_clean


title: Mouse3_CD45Primary_S72_clean


title: Mouse3_CD45Primary_S76_clean


title: Mouse3_CD45Primary_S69_clean


title: Mouse3_CD45Primary_S70_clean


title: Mouse3_CD45Primary_S71_clean


title: Mouse3_CD45Primary_S68_clean


title: SG11474142_252665248151_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_47 Day 960


title: SG11474142_252665248144_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_45 Day 83


title: SG11474142_252665248144_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_45 Day 0


title: SG11474142_252665248145_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_45 Day 209


title: Mouse3_CD45Primary_S63_clean


title: Mouse3_CD45Primary_S65_clean


title: SG11474142_252665248144_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_45 Day 14


title: Mouse2_GFPSpleenMet_S27_clean

source_name: Mouse2_Spleen Metastasis

value: Spleen

value: GFP, Calcien Violet for Live/Dead


title: Mouse2_GFPSpleenMet_S28_clean


title: SG11474142_252665248015_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_46 Day 395


title: SG11474142_252665248138_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_44 Day 49

value: Non MDR


title: Mouse2_GFPSpleenMet_S29_clean


title: SG11474142_252665248014_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_46 Day 14


title: Mouse2_GFPSpleenMet_S26_clean


title: SG11474142_252665248137_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_44 Day 14


title: SG11474142_252665248137_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_44 Day 2


title: Mouse3_CD45Primary_S67_clean

source_name: Mouse3_Primary Pancreatic Tumor


title: SG11474142_252665248149_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_43 Day 44


title: Mouse2_GFPSpleenMet_S23_clean


title: Mouse3_CD45Primary_S66_clean


title: SG11474142_252665248145_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_45 Day 111


title: SG11474142_252665248138_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_44 Day 93


title: Mouse2_GFPSpleenMet_S24_clean


title: SG11474142_252665248149_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_43 Day 18


title: Mouse2_GFPSpleenMet_S22_clean


title: SG11474142_252665248149_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_43 Day 184


title: SG11474142_252665248148_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_43 Day 1


title: SG11474142_252665248138_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_44 Day 206


title: Mouse2_GFPSpleenMet_S21_clean


title: SG11474142_252665248149_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_43 Day 16


title: Mouse2_GFPSpleenMet_S20_clean


title: SG11474142_252665248146_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_42 Day 182


title: Mouse2_GFPSpleenMet_S19_clean


title: SG11474142_252665248145_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_42 Day 89


title: Mouse2_GFPSpleenMet_S18_clean

source_name: Mouse2_Spleen Metastasis


title: Mouse2_GFPSpleenMet_S17_clean


title: SG11474142_252665248154_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_42 Day 328


title: SG11474142_252665248145_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_42 Day 0


title: Mouse2_GFPSpleenMet_S15_clean


title: Mouse2_GFPSpleenMet_S16_clean


title: Mouse2_GFPSpleenMet_S25_clean


title: Mouse2_GFPSpleenMet_S13_clean


title: Mouse2_GFPSpleenMet_S14_clean


title: Mouse2_GFPSpleenMet_S12_clean


title: Mouse2_GFPPrimary_S32_clean

source_name: Mouse2_Primary Pancreatic Tumor


title: Mouse2_GFPSpleenMet_S11_clean


title: Mouse2_GFPSpleenMet_S10_clean


title: Mouse2_GFPPrimary_S31_clean


title: SG11474142_252665248025_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_39 Day 309


title: SG11474142_252665248039_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_41 Day 62


title: SG11474142_252665248043_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_40 Day 54


title: SG11474142_252665248004_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_41 Day 13


title: Mouse2_GFPPrimary_S29_clean


title: SG11474142_252665248191_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_42 Day 64


title: SG11474142_252665248039_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_41 Day 0


title: SG11474142_252665248010_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_40 Day 210


title: SG11474142_252665248025_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_39 Day 441


title: Mouse2_GFPPrimary_S30_clean


title: Mouse2_GFPPrimary_S28_clean


title: SG11474142_252665248025_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_39 Day 188


title: SG11474142_252665248023_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_39 Day 0


title: Mouse2_GFPPrimary_S27_clean


title: SG11474142_252665248023_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_39 Day 58


title: Mouse2_GFPPrimary_S25_clean


title: Mouse2_GFPPrimary_S24_clean


title: SG11474142_252665248190_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_39 Day 617


title: SG11474142_252665248138_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_38 Day 1


title: Mouse2_GFPPrimary_S23_clean


title: Mouse2_GFPPrimary_S21_clean


title: Mouse2_GFPPrimary_S22_clean


title: SG11474142_252665248139_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_38 Day 236


title: SG11474142_252665248139_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_38 Day 175


title: Mouse2_GFPPrimary_S19_clean


title: Mouse2_GFPPrimary_S20_clean


title: SG11474142_252665248154_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_38 Day 370


title: SG11474142_252665248023_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_39 Day 93


title: Mouse2_GFPPrimary_S17_clean

source_name: Mouse2_Primary Pancreatic Tumor


title: SG11474142_252665247087_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_37 Day 319


title: SG11474142_252665247086_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_37 Day 13


title: SG11474142_252665247087_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_37 Day 426


title: SG11474142_252665248139_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_38 Day 40


title: SG11474142_252665248139_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_38 Day 90


title: Mouse2_GFPPrimary_S11_clean


title: SG11474142_252665247087_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_37 Day 578


title: Mouse2_GFPPrimary_S15_clean


title: Mouse2_GFPPrimary_S14_clean


title: Mouse2_GFPPrimary_S13_clean


title: Mouse2_GFPPrimary_S16_clean


title: Mouse2_GFPPrimary_S10_clean


title: Mouse2_GFPPrimary_S09_clean


title: Mouse2_GFPPrimary_S12_clean


title: SG11474142_252665248039_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_36 Day 446


title: Mouse2_GFPPrimary_S08_clean


title: SG11474142_252665247086_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_37 Day 0


title: Mouse2_GFPPrimary_S07_clean


title: SG11474142_252665248010_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_40 Day 69


title: Mouse2_GFPPrimary_S18_clean


title: SG11474142_252665248008_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_36 Day 601


title: SG11474142_252665248008_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_36 Day 301


title: Mouse2_GFPPrimary_S06_clean


title: SG11474142_252665248008_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_36 Day 181


title: Mouse2_GFPPrimary_S05_clean


title: SG11474142_252665247086_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_37 Day 60


title: SG11474142_252665247086_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_37 Day 209


title: SG11474142_252665248189_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_37 Day 1027


title: SG11474142_252665248007_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_36 Day 60


title: SG11474142_252665248028_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_35 Day 38


title: SG11474142_252665248007_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_36 Day 0


title: Mouse2_GFPPrimary_S02_clean

source_name: Mouse2_Primary Pancreatic Tumor


title: Mouse2_GFPPrimary_S04_clean


title: Mouse2_GFPPrimary_S01_clean


title: SG11474142_252665248007_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_36 Day 11


title: Mouse2_GFPPrimary_S03_clean


title: Mouse2_GFPPeritoneumMet_S60_clean

source_name: Mouse2_Peritoneum Metastasis

value: Peritoneum


title: SG11474142_252665248028_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_35 Day 13


title: Mouse2_GFPPrimaryBulk_S26_clean


title: Mouse2_GFPPeritoneumMet_S59_clean


title: SG11474142_252665248011_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_34 Day 188


title: Mouse2_GFPPeritoneumMet_S58_clean


title: SG11474142_252665248011_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_34 Day 40


title: SG11474142_252665248028_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_35 Day 0


title: SG11474142_252665247084_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_33 Day 13


title: Mouse2_GFPPeritoneumMet_S56_clean


title: Mouse2_GFPPeritoneumMet_S57_clean


title: Mouse2_GFPPeritoneumMet_S55_clean


title: SG11474142_252665248151_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_32 Day 610


title: SG11474142_252665247083_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_33 Day 6


title: SG11474142_252665248151_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_32 Day 512


title: Mouse2_GFPPeritoneumMet_S53_clean


title: Mouse2_GFPPeritoneumMet_S54_clean


title: Mouse2_GFPPeritoneumMet_S51_clean


title: SG11474142_252665248150_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_32 Day 177


title: SG11474142_252665248150_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_32 Day 59


title: SG11474142_252665248150_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_32 Day 16


title: Mouse2_GFPPeritoneumMet_S49_clean


title: Mouse2_GFPPeritoneumMet_S48_clean


title: Mouse2_GFPPeritoneumMet_S50_clean


title: SG11474142_252665248003_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_35 Day 208


title: SG11474142_252665248189_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_31 Day 747


title: Mouse2_GFPPeritoneumMet_S46_clean


title: Mouse2_GFPPeritoneumMet_S47_clean


title: Mouse2_GFPPeritoneumMet_S45_clean


title: SG11474142_252665248150_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_32 Day 1


title: SG11474142_252665248152_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_31 Day 468


title: Mouse2_GFPPeritoneumMet_S44_clean


title: SG11474142_252665247084_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_33 Day 1


title: SG11474142_252665248143_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_31 Day 74


title: Mouse2_GFPPeritoneumMet_S42_clean

source_name: Mouse2_Peritoneum Metastasis


title: SG11474142_252665248143_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_31 Day 186


title: Mouse2_GFPPeritoneumMet_S40_clean


title: Mouse2_GFPPeritoneumMet_S41_clean


title: SG11474142_252665248144_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_31 Day 343


title: SG11474142_252665248143_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_31 Day 28


title: SG11474142_252665248143_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_31 Day 11


title: Mouse2_GFPPeritoneumMet_S39_clean


title: SG11474142_252665246659_S001_GE1_1105_Oct12_1_1

source_name: Pat_Valid_30 Day 2


title: Mouse2_GFPPeritoneumMet_S38_clean


title: SG11474142_252665246660_S001_GE1_1105_Oct12_1_2

source_name: Pat_Valid_30 Day 608


title: SG11474142_252665248189_S001_GE1_1105_Oct12_1_3

source_name: Pat_Valid_31 Day 879


title: Mouse2_GFPPeritoneumMet_S36_clean


title: SG11474142_252665246659_S001_GE1_1105_Oct12_1_4

source_name: Pat_Valid_30 Day 179


title: Mouse2_GFPLiverMet_S11_clean

source_name: Mouse2_Liver Metastasis

value: Liver