title: TACE_Response_206


title: TACE_Response_207

status: Public on Oct 01 2020

type: RNA

city: Singapore

first: Kam

last: Hui

address: 11 Hospital Drive

country: Singapore

institute: National Cancer Centre Singapore

description: Gene expression data from HCC Tissue sample of TACE_Response patient

hyb_protocol: The final cRNA obtained was hybridized to the GeneChip Human Genome U133 Plus 2.0 Array (Affymetrix, USA).

scan_protocol: GeneChips were scanned using the Affymetrix GeneChip Scanner 3000.

data_processing:
The data was analysed using Partek Genomics Suite version 6.6.  CEL files were imported into Partek with GCRMA background correction, quantile normalisation, log2-transformation, and batch effects were removed based on scan date factor.
GCRMA processed log2 signal intensity after batch effect removal using Partek Genomics Suite version 6.6.

label: biotin

molecule: total RNA

organism: Homo sapiens

source_name: Tissue RNA sample from HCC TACE_Response patient

label_protocol: Five micrograms of total RNA were reversely-transcribed and labeled with biotin.

growth_protocol: Comprehensive gene expression profiling was conducted using biopsied tumor tissues obtained from patients with unresectable HCC prior to TACE treatment.  The present study was performed as a continuing study, according to the clinical trial registered at http://ClinicalTrials.gov (No. NCT00493402).

extract_protocol: Total RNA was extracted using TRIzol reagent (Invitrogen, USA) according to the manufacturer’s protocol.

treatment_protocol: All patients recruited in this study were treated with the same TACE regimen.

tag: subject status

value: hepatocellular carcinoma (HCC) patient

tag: subject subgroup

value: TACE responders

tag: sample source

value: Liver Tissue; tumor biopsy


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E7_ad002

type: SRA

city: La Jolla

first: Joseph

middle: R

last: Ecker

state: CA

address: 10010 North Torrey Pines Road

department: Genomic Analysis Laboratory

country: USA

institute: HHMI-Salk-Institute

library_source: genomic

data_processing:
Library strategy: snmC-seq2
Reads trimed with Cutadapt for adapters and low quality bases (Phred score >= 20)
The resulting files are mapped to in-silico bisulfite converted mm10 reference genome using Bismark.
The raw BAM file will be filtered using samtools to filter reads by MAPQ > 10 and use Picard to remove PCR duplicates
Tab-delimited files (ALLC files) describing the quantity of unmethylated and methylated cytosine base calls will be generated with in-house developing package using the filtered BAM files
Genome_build: mm10
Supplementary_files_format_and_content: tab-delimited files (ALLC files) describing the quantity of unmethylated and methylated cytosine base calls. Columns are: 1. Chromosome, 2. Position, 3. Strand, 4. Cytosin Context, 5. methylated base call, 6. total mapped base call, 7. not used, place holder column

molecule: genomic DNA

organism: Mus musculus

source_name: C57BL/6J Male P56 Mouse Brain

growth_protocol: All mice are C57BL/6J Male, brain dissected in P56

extract_protocol:
the brain of P56 male C57BL/6J mouse will be removed and cut into 600 microns thick coronal sections using a tissue matrix. Then each region will be microdissected from the coronal tissue sections based on identified landmarks and brain atlas coordinates, as defined in Allen brain atlas CCF3 (Avaliable at: http://atlas.brain-map.org). For each dissection region, the tissue from several littermate mice will be combined together into to separate replicate groups. The number of animals in a replicate depends on the size of the tissue. Nuclei preparation will be stained with the fluorescently labeled anti-NeuN body and nucleic acid stain Hoechst 33342.
Library prepared following protocol discribed in Luo, Chongyuan, Angeline Rivkin, Jingtian Zhou, Justin P. Sandoval, Laurie Kurihara, Jacinta Lucero, Rosa Castanon, et al. 2018. “Robust Single-Cell DNA Methylome Profiling with snmC-seq2.” Nature Communications 9 (1): 3824.

tag: brain region

value: ACA,PL,ILA

tag: Sex

value: male

tag: age

tag: strain


title: TACE_Response_200


title: TACE_Response_312


title: TACE_Response_203


title: Entrectinib_Dose2_Rep2

city: Chicago

first: Sonia

last: Brockway

state: IL

address: 303 E Superior St, SQBRC 7-500

department: Biochemistry and Molecular Genetics

institute: Northwestern University

data_processing:
Library strategy: QMAP-Seq
Individual samples were demultiplexed based on i5 and i7 index sequences by running bcl2fastq Conversion Software (Illumina).
Data was processed using QMAP-Seq bioinformatic analysis pipeline (https://github.com/mendillolab/QMAP-Seq). Briefly, sgRNA and cell line barcode sequences were extracted from Read 1 sequences as follows: [ACACCG][sgRNA:20][Interval:102][CellLineBarcode:8]. The number of reads for each cell line-sgRNA pair was counted, allowing up to one nucleotide mismatch per barcode. Cell number was interpolated from sequencing reads using sample-specific standard curves. The number of cells for a compound-treated sample was normalized to the median number of cells for the DMSO-treated samples.
Data was filtered using the following exclusion criteria. First, samples with low read counts were excluded. Second, cell line-sgRNA pairs with high variation (standard deviation of log2(cell number) > 0.7) were excluded. Third, compounds with an AUC > 550 for any cell line-sgRNA pair were excluded. Fourth, noncytotoxic cell line-compound pairs (relative cell number of sgNT with highest dose ≥ 90%) were excluded. Fifth, cell line-compound pairs without a dose-dependent reduction in cell viability (difference in relative cell number of sgNT between lowest and highest dose < 25%) were excluded.
Genome_build: N/A (sgRNA library sequencing)
Supplementary_files_format_and_content: Plain text document (.txt) files with read counts for each cell line-sgRNA pair. Individual files for each sample.
Supplementary_files_format_and_content: Comma-separated values (.csv) file with relative cell numbers (i.e., cell number (%DMSO)) for each cell line-sgRNA-compound-dose-replicate combination. Matrix table with data for all samples.

source_name: Pool of 5 breast cancer cell lines

growth_protocol: Cell line pools were cultured in RPMI-1640, 10% Tet System Approved FBS, 1% Penicillin/Streptomycin, 100 ng/mL doxycycline for 7 days prior to compound treatment.

extract_protocol:
Cell line pools were lysed with lysis buffer (10% 10x Taq DNA Polymerase Buffer, 0.45% IGEPAL CA-630, 0.45% TWEEN 20, 10% Proteinase K, 79.1% Nuclease-Free Water) containing cell spike-in standards. Cells were incubated at 60°C for 1 hour. Proteinase K from lysis buffer was inactivated at 95°C for 15 minutes.
Barcoded region was PCR amplified with a unique set of indexed primers for each sample. PCR products were pooled and purified twice. Sequencing library was diluted, combined with PhiX, denatured, and sequenced on a NovaSeq 6000 (Illumina).

treatment_protocol: Cell line pools were treated with compound or DMSO over a four-point concentration range (10-fold dilutions) in duplicate using either a standard dose range (10 nM to 10 μM) or a low dose range (1 nM to 1 μM). Dose1=lowest dose. Dose4=highest dose. Cells were treated for 72 hours.

tag: cell lines

tag: sgrnas

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2

tag: compound treatment


title: TACE_Response_191


title: TACE_Response_192


title: TACE_Response_194


title: TACE_Response_188


title: Phloretin_Dose2_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad012


title: AZD8186_Dose2_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E7_ad008


title: ABT199_Dose2_Rep2


title: RO4929097_Dose2_Rep2


title: TACE_Response_189


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad007


title: GSK2636771_Dose2_Rep2


title: PF573228_Dose2_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad010


title: Veliparib_Dose2_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad006


title: TACE_Response_180


title: Ganetespib_Dose2_Rep1


title: TACE_Response_175


title: TACE_Response_152


title: TACE_Response_159


title: TACE_Response_179


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad002


title: TACE_Response_151


title: TACE_Response_183


title: TACE_Response_185


title: TACE_Response_144


title: TACE_Response_158


title: TACE_Non-Response_10

description: Gene expression data from HCC Tissue sample of  TACE_Non-Response patient

source_name: Tissue RNA sample from HCC TACE_Non-Response patient

value: TACE non-responders


title: TACE_Response_145


title: TACE_Response_134


title: TACE_Response_143


title: TACE_Response_121


title: TACE_Response_177


title: GSK4112_Dose2_Rep1


title: TACE_Response_124


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad008


title: TACE_Response_116


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E6_ad004


title: TACE_Response_141


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad012


title: YM155_Dose2_Rep1


title: StemRegenin1_Dose2_Rep1


title: GSKJ4_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad007


title: TACE_Response_115


title: Triptolide_Dose2_Rep1


title: TACE_Response_112


title: TACE_Response_99


title: BIX01294_Dose2_Rep1


title: TACE_Response_96


title: TACE_Response_84


title: TACE_Response_82


title: TACE_Response_83


title: TACE_Response_98


title: TACE_Response_76


title: ZSTK474_Dose2_Rep1


title: Istradefylline_Dose2_Rep1


title: OSI027_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad010


title: CAL101_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E5_ad002


title: TACE_Response_48


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad012


title: TACE_Response_71


title: TACE_Response_44


title: Semagacestat_Dose2_Rep1


title: TACE_Response_39


title: TACE_Response_22


title: TACE_Response_38


title: Linifanib_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad010


title: TACE_Response_52


title: TACE_Response_28


title: TACE_Response_21


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad006


title: TACE_Response_15


title: PF3758309_Dose2_Rep1


title: TACE_Response_37


title: Afatinib_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad004


title: KU60019_Dose2_Rep1


title: TACE_Response_12


title: TACE_Response_40


title: TACE_Response_6


title: TACE_Response_7


title: Lomeguatrib_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad002


title: TACE_Response_5


title: TACE_Response_1


title: TACE_Response_2


title: TACE_Response_3


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E4_ad008


title: TACE_Response_13


title: TubastatinA_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E3_ad012


title: DMSOPlate11WellF10_Dose2_Rep1


title: DMSOPlate11WellC10_Dose2_Rep1


title: KW2449_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E3_ad006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E3_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E3_ad004


title: EX527_Dose2_Rep1


title: T341_Xenograft_Generation_3

type: genomic

city: Luxembourg

first: Ann-Christin

last: Hau

address: 1, Rue Louis Rech

department: National Center of Pathology

country: Luxembourg

institute: Laboratoire National de sante

hyb_protocol: Similarly treated amounts of reference; Female or Male gDNA pool (Promega) were processed as sample genomic DNAs and hybridized with the Agilent Oligo aCGH Hybridization Kit to the corresponding platform array at 65°C for 24h or 48h respectively.

scan_protocol: Microarray slides were scanned using an Agilent 2565C DNA scanner

data_processing:
The tif images were analyzed with Agilent Feature Extraction version 12.5, using default settings
normalised log ratio Cy5/Cy3 representing test/reference; transformed logratio matrix with 0 - unaltered, 1 - gain, -1 - loss, 2 - amplification, -2 - deletion

source_name: Xenotransplant

label_protocol: For Agilent-021529 platform 2µg, for Agilent-021850 and Agilent-028081 platform 1µg, for Agilent-030587 platform 500ng and for Agilent-021924 platform 250ng of genomic DNA  were digested with RSA1 and Alu1 (Agilent) to generate 200-500bp large fragments. The BioPrime aCGH Genomic labeling Kit (Life Technologies) and Cy3 and Cy5 dyes (GE Healthcare) were used following standard protocols for Agilent aCGH (CGH enzymatic protocol v6.2; Ref # G4410-90010).

growth_protocol: patient specimen were: 1) flash frozen on dry ice after surgical removal or 2) mechanically cut, seeded on agar coated flasks (0.85%) and allowed to form spheroids for up to 2 weeks at 37°C under 5% CO2 and atmospheric oxygen in DMEM medium, 10% FBS, 2mM L-Glutamine, 0.4mM NEAA and 100U/ml Pen-Strep (all from Lonza).  Spheroids (generation 0) with a diameter of 300-1000 µm were then implanted in the brain of immunodeficient mice (NOD/Scid, Nude or NSG; 6 spheroids per mice). Cell lines were derived from xenotransplanted mice by papain-based enzymatic digestion of PDOX tissue and cultured in serum-free medium based on  Neurobasal® base medium (Life Technologies) supplemented with 1 x B27 (Life Technologies) 2 mM L-Glutamine, 30 U/ml Pen-Step, 1 U/ml Heparin (Sigma), 20 ng/ml bFGF (Miltenyi, 130-093-841) and 20 ng/ml EGF (Provitro, 1325950500).

extract_protocol: Genomic DNA was isolated from patient tissue, spheroid cultures or cell lines using the AllPrep DNA/RNA Mini Kit® (Qiagen) following manufacturer’s instructions for “Simultaneous purification of genomic DNA and total RNA from animal tissues”.

tag: sample type

value: Xenotransplant

tag: gender

value: Female

source_name: Reference DNA

value: Reference DNA

tag: catalog no


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E3_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad001


title: T386_Xenograft_Generation_3

value: Male


title: T434_Xenograft_Generation_4


title: T251_Xenograft_Generation_3


title: P3_cell-line_passage_12

source_name: Cell Line

value: Cell Line


title: NSC74859_Dose2_Rep1


title: T476_Xenograft_Generation_3


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E3_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad006


title: AZD5363_Dose2_Rep1


title: Belinostat_Dose2_Rep1


title: T238_Xenograft_Generation_3


title: T331_Xenograft_Generation_2


title: T101_Xenograft_Generation_5_Sample_1


title: Olaparib_Dose2_Rep1


title: T407_Xenograft_Generation_3


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad007


title: GDC0941_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad002


title: GSK1059615_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E12_ad012


title: T185_Xenograft_Generation_4


title: Teniposide_Dose2_Rep1


title: PX12_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E2_ad004


title: P8_Xenograft_Generation_10


title: Bortezomib_Dose2_Rep1


title: BetulinicAcid_Dose2_Rep1


title: AZD4547_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E12_ad004


title: Navitoclax_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad010


title: MLN2238_Dose2_Rep1


title: GSK461364_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E12_ad008


title: BGJ398_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad012


title: FourHydroxytamoxifen_Dose2_Rep1


title: T186_Xenograft_Generation_3


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E12_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E12_ad006


title: Isoliquiritigenin_Dose2_Rep1


title: MK1775_Dose2_Rep1


title: Mdivi1_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E12_ad001


title: IBET151_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad012


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad001


title: Entinostat_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad007


title: Neratinib_Dose2_Rep1


title: Masitinib_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E11_ad004


title: Spautin1_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad010


title: BMS754807_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad007


title: 67800: AEHL151

city: Philadelphia

first: Jonathan

last: Schug

state: Pennsylvania

address: 12-156 Smilow Ctr Trans Research

department: School of Medicine

institute: University of Pennsylvania

library_source: transcriptomic

data_processing:
Illumina basecalling with bcl2fastq, various versions
Read alignment and expression calculation; using RUM (Grant et al. Bioinformatics  doi: 10.1093/bioinformatics/btr427)
Conversion from reads to trimmed normalized CPMs.  Briefly CPMs for genes between 25 to 75% quantiles were used to compute a normalization factor which was then applied to all CPMs.
Manual and semi-automated cell type calling. Marker genes and differentially expressed genes used to rate cell type and purity which was subsequently curated.
Genome_build: hg19
Supplementary_files_format_and_content: TSV files with raw rea counts or normalized CPMs.  Donor annotation and called cell types included as well.

molecule: polyA RNA

extract_protocol: Fluidigm C1 single-cell RNA-Seq using 96-well chip

tag: tissue

value: pancreas

tag: celltype

value: pancreatic islets

tag: agecategory

value: adult

tag: healthcategory

tag: combinedcategory

value: dropped


title: 67798: AEHL151

value: alpha


title: 67801: AEHL151

value: mesenchyme


title: 67797: AEHL151

value: duct


title: 67796: AEHL151

value: beta


title: SB743921_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad004

value: ACA,PL,ILA


title: 67795: AEHL151


title: AZD7545_Dose2_Rep1


title: DMSOPlate11WellF6_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad002

value: male


title: STF083010_Dose2_Rep1

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: SNS032_Dose2_Rep1


title: 67793: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad001


title: 67791: AEHL151


title: 67792: AEHL151


title: 67789: AEHL151


title: DMSOPlate11WellC6_Dose2_Rep1


title: 67788: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E10_ad006


title: MG132_Dose2_Rep1


title: 67799: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad012


title: 67785: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad007


title: 67784: AEHL151


title: 67782: AEHL151

value: pp


title: KU0063794_Dose2_Rep1


title: SN38_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad010


title: Erastin_Dose2_Rep1


title: 67778: AEHL151


title: 67777: AEHL151


title: 67775: AEHL151


title: 67776: AEHL151


title: 67787: AEHL151


title: PifithrinAlpha_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad002


title: 67772: AEHL151


title: BMS345541_Dose2_Rep1


title: WAY362450_Dose2_Rep1


title: 67771: AEHL151


title: 67764: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad006


title: 67765: AEHL151


title: 67781: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad001


title: 67783: AEHL151


title: 67780: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad012


title: 67762: AEHL151


title: 67767: AEHL151


title: Canertinib_Dose2_Rep1


title: 67760: AEHL151


title: Palbociclib_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad007


title: Purmorphamine_Dose2_Rep1


title: 67759: AEHL151


title: Methotrexate_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_E1_ad004


title: 67757: AEHL151


title: Etomoxir_Dose2_Rep1


title: 67756: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad004


title: 67755: AEHL151

value: masked


title: Necrostatin1_Dose2_Rep1


title: TG101348_Dose2_Rep1


title: 67751: AEHL151


title: 67761: AEHL151


title: SU11274_Dose2_Rep1


title: 67750: AEHL151


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad002


title: 67749: AEHL151


title: P3_Xenograft_Generation_11

value: Xenotransplant


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D9_ad008


title: 67747: AEGY230A


title: 67748: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad002


title: 67745: AEGY230A


title: 67743: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad010


title: SixMercaptopurine_Dose2_Rep1


title: 67746: AEGY230A


title: 67744: AEGY230A


title: 67753: AEHL151


title: BMS536924_Dose2_Rep1


title: SJ172550_Dose2_Rep1


title: 67739: AEGY230A


title: 67737: AEGY230A


title: 67736: AEGY230A


title: GSK2636771_Dose2_Rep1


title: 67735: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad004


title: JQ1_Dose2_Rep1


title: 67734: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad001


title: DMSOPlate11WellF3_Dose2_Rep1


title: 67733: AEGY230A


title: 67731: AEGY230A


title: 67728: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad012


title: ETP46464_Dose2_Rep1


title: 67729: AEGY230A


title: 67726: AEGY230A


title: 67727: AEGY230A


title: Curcumin_Dose2_Rep1


title: DMSOPlate11WellC3_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D8_ad006


title: PAC1_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad001


title: 67730: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad007


title: 67724: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad006


title: 67738: AEGY230A


title: 67723: AEGY230A


title: LRRK2IN1_Dose2_Rep1


title: 67720: AEGY230A


title: 67725: AEGY230A


title: TPCA1_Dose2_Rep1


title: 67721: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad004


title: 67719: AEGY230A


title: PI103_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad012


title: 67715: AEGY230A


title: 67717: AEGY230A


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad008


title: Ifosfamide_Dose2_Rep1


title: 63222: HPAP011

value: toddler

value: control

value: Toddler


title: 63219: HPAP011

value: pancreas


title: 63223: HPAP011

value: pancreatic islets


title: 63224: HPAP011


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad001


title: AT7867_Dose2_Rep1


title: 63220: HPAP011


title: 63217: HPAP011


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad007


title: 63215: HPAP011


title: ABT737_Dose2_Rep1


title: 63216: HPAP011


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad012


title: DBeQ_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad006


title: 63213: HPAP011


title: APY29_Dose2_Rep1


title: 63210: HPAP011


title: 67718: AEGY230A

value: adult


title: 63212: HPAP011

value: acinar


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D7_ad002


title: Gossypol_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad004


title: GDC0879_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad002


title: IC87114_Dose2_Rep1


title: 63209: HPAP011


title: 63214: HPAP011

value: dropped


title: 63200: HPAP011


title: Entrectinib_Dose2_Rep1


title: 63203: HPAP011


title: RO4929097_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad012


title: 63196: HPAP011


title: 63197: HPAP011

value: alpha


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D6_ad010


title: 63208: HPAP011


title: AZD8186_Dose2_Rep1


title: 63207: HPAP011


title: 63199: HPAP011


title: 63195: HPAP011


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad006


title: 55792: AEBK009


title: ABT199_Dose2_Rep1


title: 63193: HPAP011


title: 55791: AEBK009


title: Phloretin_Dose2_Rep1


title: PF573228_Dose2_Rep1


title: 55790: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad004


title: 55788: AEBK009


title: 55789: AEBK009


title: Veliparib_Dose2_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad002


title: 55786: AEBK009


title: Ganetespib_Dose1_Rep2


title: 55781: AEBK009

value: duct


title: YM155_Dose1_Rep2


title: 55776: AEBK009


title: 55777: AEBK009


title: 55779: AEBK009

value: beta


title: GSK4112_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D4_ad007

value: ACA,PL,ILA


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D5_ad008

value: male


title: 55775: AEBK009


title: CAL101_Dose1_Rep2

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D4_ad004


title: 55767: AEBK009


title: 55769: AEBK009


title: GSKJ4_Dose1_Rep2


title: 55771: AEBK009


title: StemRegenin1_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D4_ad002


title: 55768: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D4_ad008


title: 55765: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D4_ad001


title: ZSTK474_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D3_ad001


title: 55774: AEBK009


title: 55764: AEBK009


title: 55773: AEBK009


title: 55762: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D3_ad010


title: Istradefylline_Dose1_Rep2


title: 55763: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D3_ad006


title: OSI027_Dose1_Rep2


title: 55758: AEBK009


title: Triptolide_Dose1_Rep2


title: 55761: AEBK009


title: 55756: AEBK009


title: BIX01294_Dose1_Rep2


title: 55754: AEBK009


title: Linifanib_Dose1_Rep2


title: 55752: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D3_ad002


title: 55766: AEBK009


title: Palbociclib_Dose1_Rep2


title: 55750: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D3_ad008


title: 55755: AEBK009


title: 55747: AEBK009


title: 55748: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad012


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad007


title: Semagacestat_Dose1_Rep2


title: 55743: AEBK009


title: 55740: AEBK009

value: mesenchyme


title: 55744: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D3_ad004


title: PF3758309_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad010


title: Afatinib_Dose1_Rep2


title: 55739: AEBK009


title: 55734: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad004


title: 55733: AEBK009


title: 55737: AEBK009


title: 46046: ADFY260

value: adolescent

value: Adolescent


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad002


title: 55759: AEBK009


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad008


title: 46044: ADFY260


title: 46045: ADFY260


title: Lomeguatrib_Dose1_Rep2


title: 46043: ADFY260


title: DMSOPlate10WellF10_Dose1_Rep2


title: KW2449_Dose1_Rep2


title: 46040: ADFY260


title: TubastatinA_Dose1_Rep2


title: 46041: ADFY260


title: KU60019_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D2_ad006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D12_ad012


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D12_ad010


title: 55738: AEBK009


title: 46042: ADFY260


title: DMSOPlate10WellC10_Dose1_Rep2


title: 46039: ADFY260


title: 46037: ADFY260


title: EX527_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D12_ad007


title: 46036: ADFY260


title: 46035: ADFY260


title: NSC74859_Dose1_Rep2


title: 46034: ADFY260


title: 46038: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D12_ad004


title: 46031: ADFY260


title: 46032: ADFY260


title: 46033: ADFY260


title: AZD5363_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D12_ad001


title: 46030: ADFY260


title: Olaparib_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D12_ad006


title: 46028: ADFY260


title: 63206: HPAP011

value: toddler


title: 46029: ADFY260

value: control


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D11_ad008


title: 46026: ADFY260


title: 46027: ADFY260


title: 46025: ADFY260


title: Belinostat_Dose1_Rep2


title: GSK1059615_Dose1_Rep2


title: Teniposide_Dose1_Rep2


title: 46024: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D11_ad006


title: 46023: ADFY260

value: delta


title: 46022: ADFY260

value: pancreas


title: GDC0941_Dose1_Rep2


title: 46021: ADFY260

value: pancreatic islets


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D11_ad012


title: 46020: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D11_ad004


title: BetulinicAcid_Dose1_Rep2


title: 46018: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D11_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D11_ad002


title: 46017: ADFY260


title: AZD4547_Dose1_Rep2


title: 46019: ADFY260


title: 46016: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad010


title: 46015: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad008


title: Bortezomib_Dose1_Rep2


title: 46014: ADFY260


title: 46013: ADFY260


title: PX12_Dose1_Rep2


title: 46011: ADFY260


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad007


title: 46012: ADFY260


title: MK1775_Dose1_Rep2


title: 46010: ADEY348


title: Mdivi1_Dose1_Rep2


title: 46008: ADEY348


title: 46007: ADEY348


title: 46006: ADEY348


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad012


title: MLN2238_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad002


title: 46005: ADEY348


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad004


title: 46003: ADEY348


title: BGJ398_Dose1_Rep2


title: 46004: ADEY348


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad001


title: 46002: ADEY348


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C9_ad012


title: Entinostat_Dose1_Rep2


title: 46001: ADEY348

value: pp


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C9_ad010


title: 45999: ADEY348


title: CEMBA190205_5A_3_CEMBA190205_5A_4_D10_ad006


title: FourHydroxytamoxifen_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C9_ad006


title: 46009: ADEY348

value: masked


title: 45996: ADEY348


title: Masitinib_Dose1_Rep2


title: 45995: ADEY348


title: Isoliquiritigenin_Dose1_Rep2


title: GSK461364_Dose1_Rep2


title: IBET151_Dose1_Rep2


title: Spautin1_Dose1_Rep2


title: 46000: ADEY348


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C9_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C9_ad008


title: Navitoclax_Dose1_Rep2


title: 45992: ADEY348


title: 45993: ADEY348

value: dropped


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad012


title: 45998: ADEY348


title: 45991: ICRH97

value: Toddler

value: alpha


title: 45988: ICRH97


title: 45987: ICRH97


title: BMS754807_Dose1_Rep2


title: 45997: ADEY348

value: duct


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad001

value: ACA,PL,ILA


title: 45986: ICRH97


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad007

value: male


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C9_ad004


title: 45994: ADEY348


title: Neratinib_Dose1_Rep2

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: 45983: ICRH97


title: 45984: ICRH97


title: 45985: ICRH97

value: beta


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad006


title: SB743921_Dose1_Rep2


title: 45989: ICRH97


title: 45990: ICRH97


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad004


title: 45980: ICRH97


title: 45982: ICRH97


title: STF083010_Dose1_Rep2


title: 45979: ICRH97


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad002


title: 45981: ICRH97


title: DMSOPlate10WellF6_Dose1_Rep2


title: AZD7545_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C8_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C7_ad012


title: 45976: ICRH97


title: 45977: ICRH97


title: DMSOPlate10WellC6_Dose1_Rep2


title: SNS032_Dose1_Rep2


title: 45974: ICRH97


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C7_ad007


title: 45973: ICRH97


title: MG132_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C7_ad010


title: WAY362450_Dose1_Rep2


title: 45972: ICRH97


title: 45970: ADDU206

value: adult


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C7_ad006


title: 45969: ADDU206


title: 45968: ADDU206


title: KU0063794_Dose1_Rep2


title: 45967: ADDU206


title: 45978: ICRH97


title: SN38_Dose1_Rep2


title: 45966: ADDU206


title: 45964: ADDU206


title: 45963: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C7_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C7_ad008


title: Erastin_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad001


title: 45961: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad012


title: 45962: ADDU206


title: PifithrinAlpha_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad007


title: Purmorphamine_Dose1_Rep2


title: 45975: ICRH97


title: 45971: ADDU206


title: 45958: ADDU206


title: BMS345541_Dose1_Rep2


title: 45956: ADDU206


title: 45960: ADDU206


title: Canertinib_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad010


title: 45957: ADDU206


title: 45955: ADDU206


title: 45965: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad004


title: 45954: ADDU206


title: Methotrexate_Dose1_Rep2


title: 45953: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad002


title: Etomoxir_Dose1_Rep2


title: 45952: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C6_ad008


title: TG101348_Dose1_Rep2


title: 45949: ADDU206

value: acinar


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad012


title: 45948: ADDU206


title: Necrostatin1_Dose1_Rep2


title: 45947: ADDU206


title: 45959: ADDU206


title: 45946: ADDU206


title: 45945: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad007


title: 45944: ADDU206


title: SU11274_Dose1_Rep2


title: SJ172550_Dose1_Rep2


title: 45942: ADDU206


title: SixMercaptopurine_Dose1_Rep2


title: 45941: ADDU206


title: 45943: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad006


title: BMS536924_Dose1_Rep2


title: 45951: ADDU206


title: 45940: ADDU206


title: 45938: ADDU206


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad002


title: 45939: ADDU206


title: PAC1_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad008


title: 45936: ICRH85

value: newborn

value: Newbown


title: GSK2636771_Dose1_Rep2


title: 45934: ICRH85

value: control


title: 45937: ADDU206

value: pancreas


title: 45935: ICRH85

value: pancreatic islets


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad001


title: 45933: ICRH85


title: JQ1_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad012


title: 45932: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C5_ad010


title: DMSOPlate10WellF3_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad007


title: Curcumin_Dose1_Rep2


title: 45931: ICRH85


title: 45930: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad010


title: 45929: ICRH85


title: 45928: ICRH85


title: 45927: ICRH85


title: ETP46464_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad006


title: 45926: ICRH85


title: 45925: ICRH85


title: DMSOPlate10WellC3_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad004


title: 45924: ICRH85


title: 45923: ICRH85


title: TPCA1_Dose1_Rep2


title: 45922: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad002


title: 45921: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C4_ad008


title: LRRK2IN1_Dose1_Rep2


title: 45920: ICRH85


title: 45919: ICRH85


title: 45918: ICRH85


title: Gossypol_Dose1_Rep2


title: 45917: ICRH85


title: PI103_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad001


title: 45916: ICRH85


title: Ifosfamide_Dose1_Rep2


title: 45915: ICRH85


title: 45913: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad010


title: 45912: ICRH85

value: mesenchyme


title: ABT737_Dose1_Rep2


title: 45911: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad006


title: 45909: ICRH85


title: 45908: ICRH85


title: DBeQ_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad004


title: 45907: ICRH85


title: 45906: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad012


title: APY29_Dose1_Rep2


title: 45902: ICRH85


title: 45914: ICRH85


title: 45905: ICRH85


title: 45904: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C3_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad012


title: Entrectinib_Dose1_Rep2


title: AT7867_Dose1_Rep2


title: IC87114_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad001


title: Phloretin_Dose1_Rep2


title: 45900: ICRH85


title: RO4929097_Dose1_Rep2


title: 45903: ICRH85


title: 45897: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad004


title: 45901: ICRH85


title: AZD8186_Dose1_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad006


title: GDC0879_Dose1_Rep2


title: 45899: ICRH85


title: 45894: ICRH85


title: 45892: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad002


title: 45896: ICRH85


title: ABT199_Dose1_Rep2


title: 45895: ICRH85


title: 45891: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C2_ad008


title: 45889: ICRH85


title: PF573228_Dose1_Rep2


title: 45898: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad012


title: 45888: ICRH85


title: 45890: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad010


title: 45887: ICRH85


title: 45886: ICRH85


title: 45885: ICRH85


title: Ganetespib_Dose1_Rep1


title: 40148: ICRH85


title: YM155_Dose1_Rep1


title: 45884: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad008


title: GSK4112_Dose1_Rep1


title: 40147: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad007


title: 40144: ICRH85


title: 40145: ICRH85


title: 40146: ICRH85


title: StemRegenin1_Dose1_Rep1


title: CAL101_Dose1_Rep1


title: 40143: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad006


title: 40141: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C12_ad001


title: 40142: ICRH85


title: 40140: ICRH85


title: Veliparib_Dose1_Rep2


title: 40139: ICRH85


title: 40138: ICRH85


title: Istradefylline_Dose1_Rep1


title: 40137: ICRH85


title: ZSTK474_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad012


title: OSI027_Dose1_Rep1


title: 40135: ICRH85


title: Triptolide_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad007


title: 40136: ICRH85


title: 40133: ICRH85


title: 40131: ICRH85


title: 40134: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad004


title: 40128: ICRH85


title: 40130: ICRH85


title: Linifanib_Dose1_Rep1


title: GSKJ4_Dose1_Rep1


title: 40129: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad002


title: 40125: ICRH85


title: 40126: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C11_ad001


title: 40124: ICRH85


title: Semagacestat_Dose1_Rep1


title: Palbociclib_Dose1_Rep1


title: 40123: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad012


title: 40122: ICRH85


title: PF3758309_Dose1_Rep1


title: 40120: ICRH85


title: Afatinib_Dose1_Rep1


title: 40119: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad010


title: BIX01294_Dose1_Rep1


title: 40121: ICRH85


title: 40118: ICRH85

value: masked


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad007


title: 40116: ICRH85

value: dropped


title: 40117: ICRH85


title: KU60019_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad006


title: 40114: ICRH85


title: 40113: ICRH85


title: DMSOPlate9WellF10_Dose1_Rep1


title: 40127: ICRH85


title: 40112: ICRH85


title: 40115: ICRH85


title: KW2449_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad004


title: 40111: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad002


title: TubastatinA_Dose1_Rep1


title: 40108: ICRH85


title: 40110: ICRH85


title: 40109: ICRH85


title: DMSOPlate9WellC10_Dose1_Rep1


title: 40107: ICRH85


title: 40106: ICRH85


title: 40105: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad012


title: Lomeguatrib_Dose1_Rep1


title: NSC74859_Dose1_Rep1


title: EX527_Dose1_Rep1


title: AZD5363_Dose1_Rep1


title: Olaparib_Dose1_Rep1


title: 40101: ICRH85


title: 40098: ICRH95


title: 40097: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad006


title: 40100: ICRH95


title: GSK1059615_Dose1_Rep1


title: 40095: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C10_ad001


title: Belinostat_Dose1_Rep1


title: Teniposide_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad002


title: 40104: ICRH85


title: 40096: ICRH95


title: 40092: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad008


title: 40091: ICRH95


title: 40103: ICRH85


title: 40090: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad007


title: 40102: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B9_ad012


title: BetulinicAcid_Dose1_Rep1


title: AZD4547_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B9_ad001


title: 40087: ICRH95


title: 40085: ICRH95


title: GDC0941_Dose1_Rep1


title: 40094: ICRH95


title: 40093: ICRH95


title: PX12_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_C1_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B9_ad006


title: Bortezomib_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B9_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B9_ad008


title: 40089: ICRH95


title: Navitoclax_Dose1_Rep1


title: MK1775_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B8_ad012


title: Mdivi1_Dose1_Rep1


title: 40086: ICRH95


title: 40076: ICRH95


title: 40078: ICRH95


title: 40079: ICRH95


title: 40081: ICRH95


title: 40073: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B9_ad007


title: 40075: ICRH95


title: 40082: ICRH95


title: 40074: ICRH95


title: 40072: ICRH95


title: 40080: ICRH95


title: 40084: ICRH95


title: 40071: ICRH95


title: 40070: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B8_ad006


title: 40069: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B8_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B8_ad007


title: BGJ398_Dose1_Rep1


title: GSK461364_Dose1_Rep1


title: 40068: ICRH95


title: 40067: ICRH95


title: Entinostat_Dose1_Rep1


title: 40066: ICRH95


title: 40065: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B8_ad002


title: FourHydroxytamoxifen_Dose1_Rep1


title: 40064: ICRH95


title: 40061: ICRH95


title: 40062: ICRH95


title: 40059: ICRH95


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B7_ad002


title: MLN2238_Dose1_Rep1


title: Isoliquiritigenin_Dose1_Rep1


title: 40058: ICRH95


title: Masitinib_Dose1_Rep1


title: IBET151_Dose1_Rep1


title: 40055: ICRH95


title: 40051: ICRH85


title: 40052: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B7_ad004


title: Spautin1_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B7_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B7_ad010


title: 40050: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B8_ad004


title: STF083010_Dose1_Rep1


title: 40048: ICRH85


title: 40049: ICRH85


title: BMS754807_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad012


title: 40047: ICRH85


title: 40046: ICRH85


title: Neratinib_Dose1_Rep1


title: 40054: HP16012_1T2D


title: 40045: ICRH85


title: 40044: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad007


title: 40043: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B7_ad008


title: DMSOPlate9WellF6_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad001


title: 40041: ICRH85


title: 40040: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad002


title: AZD7545_Dose1_Rep1


title: 40039: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad004


title: SNS032_Dose1_Rep1


title: 40053: HP16012_1T2D


title: 40038: ICRH85


title: 40036: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B6_ad008


title: 40035: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B5_ad012


title: DMSOPlate9WellC6_Dose1_Rep1


title: 40037: ICRH85


title: MG132_Dose1_Rep1


title: 40034: ICRH85


title: SB743921_Dose1_Rep1


title: 40042: ICRH85


title: 40033: ICRH85


title: 40032: ICRH85


title: 40031: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B5_ad010


title: 40030: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B5_ad006


title: WAY362450_Dose1_Rep1


title: 40029: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B5_ad004


title: 40028: ICRH85


title: 40026: ICRH85


title: 40027: ICRH85


title: SN38_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B5_ad002


title: 40025: ICRH85


title: Erastin_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B4_ad006


title: 40024: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B4_ad008


title: 40023: ICRH85


title: 40022: ICRH85


title: 40020: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad001


title: BMS345541_Dose1_Rep1


title: PifithrinAlpha_Dose1_Rep1


title: 40019: ICRH85


title: KU0063794_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad007


title: Canertinib_Dose1_Rep1


title: 40017: ICRH85


title: 40018: ICRH85


title: 40015: ICRH85


title: 40014: ICRH85


title: 40013: ICRH85


title: Methotrexate_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad010


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad006


title: 40011: ICRH85


title: Etomoxir_Dose1_Rep1


title: Purmorphamine_Dose1_Rep1


title: 40012: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad004


title: 40010: ICRH85


title: 40009: ICRH85


title: Necrostatin1_Dose1_Rep1


title: 40007: ICRH85


title: 40006: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B3_ad002


title: 40005: ICRH85


title: SU11274_Dose1_Rep1


title: SJ172550_Dose1_Rep1


title: 40004: HP15269-01T2D


title: 40003: HP15269-01T2D


title: 40002: HP15269-01T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B2_ad001


title: 40001: HP15269-01T2D


title: 39998: HP15269-01T2D


title: 39997: HP15269-01T2D


title: TG101348_Dose1_Rep1


title: 39996: HP15269-01T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B2_ad010


title: 39994: HP15269-01T2D

value: delta


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B2_ad004


title: 39993: HP15269-01T2D


title: PAC1_Dose1_Rep1


title: BMS536924_Dose1_Rep1


title: GSK2636771_Dose1_Rep1


title: 40008: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B2_ad008


title: JQ1_Dose1_Rep1


title: 39990: HP15269-01T2D

value: alpha


title: SixMercaptopurine_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B2_ad012


title: 39989: HP15269-01T2D

value: duct


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B12_ad010

value: ACA,PL,ILA


title: 39988: HP15269-01T2D


title: Curcumin_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B2_ad007

value: male


title: 39986: HP15269-01T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B12_ad008


title: ETP46464_Dose1_Rep1

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B12_ad007


title: 39984: HP15269-01T2D


title: 39981: HP15269-01T2D

value: beta


title: 39978: HP15269-01T2D

value: adult


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B12_ad004


title: 39991: HP15269-01T2D


title: 39977: HP15269-01T2D


title: 39975: HP15269-01T2D


title: 39974: HP16012_1T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B12_ad002


title: 39976: HP15269-01T2D


title: TPCA1_Dose1_Rep1


title: DMSOPlate9WellC3_Dose1_Rep1


title: 39987: HP15269-01T2D


title: PI103_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B12_ad012


title: 39983: HP15269-01T2D


title: 39973: HP16012_1T2D


title: 39965: HP16012_1T2D


title: AT7867_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad006


title: ABT737_Dose1_Rep1


title: 39971: HP16012_1T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad004


title: DBeQ_Dose1_Rep1


title: DMSOPlate9WellF3_Dose1_Rep1


title: 39972: HP16012_1T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad012


title: LRRK2IN1_Dose1_Rep1


title: 39959: HP16012_1T2D


title: Ifosfamide_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad010


title: 39969: HP16012_1T2D


title: 39963: HP16012_1T2D


title: 39968: HP16012_1T2D


title: 39967: HP16012_1T2D


title: 39966: HP16012_1T2D

value: acinar


title: 39964: HP16012_1T2D


title: 39960: HP16012_1T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad001


title: 39962: HP16012_1T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B10_ad012


title: 39955: ICRH85

value: newborn


title: 39957: HP16012_1T2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B10_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B11_ad007


title: 39961: HP16012_1T2D


title: 39958: HP16012_1T2D


title: 39952: ICRH85

value: Newbown


title: GDC0879_Dose1_Rep1


title: 39951: ICRH85

value: control


title: RO4929097_Dose1_Rep1


title: Gossypol_Dose1_Rep1


title: IC87114_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B10_ad007


title: 39950: ICRH85

value: pancreas


title: APY29_Dose1_Rep1


title: 39956: ICRH85

value: pancreatic islets


title: 39949: ICRH85


title: Entrectinib_Dose1_Rep1


title: 39948: ICRH85


title: 39953: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B10_ad004


title: Phloretin_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B10_ad002


title: 39946: ICRH85


title: 39947: ICRH85


title: AZD8186_Dose1_Rep1


title: 39945: ICRH85


title: 39944: ICRH85


title: ABT199_Dose1_Rep1


title: 39941: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B10_ad001


title: 39942: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad012


title: PF573228_Dose1_Rep1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad007


title: 39940: ICRH85


title: 39938: ICRH85


title: BrefeldinA_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad001


title: 39943: ICRH85


title: 39936: ICRH85


title: Tivozanib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad010


title: 39937: ICRH85


title: 39934: ICRH85


title: 39935: ICRH85


title: 39939: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad006


title: 39932: ICRH85


title: 39931: ICRH85


title: Brivanib_Dose4_Rep2


title: 39933: ICRH85


title: Dasatinib_Dose4_Rep2


title: 39930: ICRH85


title: Sildenafil_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad008


title: Veliparib_Dose1_Rep1


title: 39929: ICRH85


title: 39926: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A9_ad012


title: 39927: ICRH85


title: Pazopanib_Dose4_Rep2


title: 39924: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A9_ad001


title: 39925: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A9_ad007


title: 39922: ICRH85


title: 39923: ICRH85


title: Saracatinib_Dose4_Rep2


title: PYR41_Dose4_Rep2


title: 39920: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A9_ad002


title: 39917: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad002


title: 39916: ICRH85


title: 39919: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A9_ad008


title: Rigosertib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_B1_ad004


title: Everolimus_Dose4_Rep2


title: 39915: ICRH85


title: 39914: ICRH85


title: 39913: ICRH85


title: 39912: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A8_ad012


title: 39928: ICRH85


title: Chlorambucil_Dose4_Rep2


title: 39911: ICRH85


title: 39910: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A8_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A9_ad006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A8_ad007


title: Topotecan_Dose4_Rep2


title: 39909: ICRH85


title: 39907: ICRH85


title: 39921: ICRH85


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A8_ad010


title: 39904: ACHL274

value: Adult


title: Ornidazole_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A8_ad006


title: Gemcitabine_Dose4_Rep2


title: RG108_Dose4_Rep2


title: Ciclopirox_Dose4_Rep2


title: Lovastatin_Dose4_Rep2


title: 39906: ACHL274


title: 39903: ACHL274


title: 39902: ACHL274


title: KU55933_Dose4_Rep2


title: DMSOPlate8WellF10_Dose4_Rep2


title: 39898: ACHL274


title: 39901: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad001


title: Paclitaxel_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad010


title: 39908: ICRH85


title: 39897: ACHL274


title: 39894: ACHL274


title: 39895: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad006


title: Nitroxoline_Dose4_Rep2


title: 39893: ACHL274


title: DMSOPlate8WellC10_Dose4_Rep2


title: 39890: ACHL274


title: 39891: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad004


title: Lapatinib_Dose4_Rep2


title: 39887: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad012


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A8_ad004


title: 39889: ACHL274


title: 39900: ACHL274


title: DimethylFumarate_Dose4_Rep2


title: Selumetinib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad008


title: 39899: ACHL274


title: 39888: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A7_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad012


title: Tivantinib_Dose4_Rep2


title: 39884: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad001


title: 39883: ACHL274


title: 39882: ACHL274

value: mesenchyme


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad007


title: 39892: ACHL274


title: 39880: ACHL274


title: 39881: ACHL274

value: dropped


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad010


title: RacRotigotine_Dose4_Rep2


title: 39879: ACHL274


title: 39878: ACHL274


title: Vincristine_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad006


title: 39877: ACHL274


title: 39874: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A6_ad004


title: Trifluoperazine_Dose4_Rep2


title: 39873: ACHL274


title: 39885: ACHL274


title: 39876: ACHL274


title: Crizotinib_Dose4_Rep2


title: 39871: ACHL274


title: 39872: ACHL274


title: Carfilzomib_Dose4_Rep2


title: 39875: ACHL274


title: 39886: ACHL274


title: 39868: ACHL274


title: 39866: ACHL274


title: 39869: ACHL274


title: 39870: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A5_ad010


title: 39865: ACHL274


title: STF31_Dose4_Rep2


title: Cyclophosphamide_Dose4_Rep2


title: WP1130_Dose4_Rep2


title: BardoxoloneMethyl_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A5_ad006


title: 39864: ACHL274


title: Simvastatin_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A5_ad001


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A5_ad002


title: 39862: ACHL274


title: 39860: ACJW006

value: toddler

value: Toddler


title: FiveFluorouracil_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad012


title: Etoposide_Dose4_Rep2


title: 39859: ACJW006


title: 39861: ACHL274


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A5_ad012


title: 39857: ACJW006


title: Letrozole_Dose4_Rep2


title: 39858: ACJW006


title: 39856: ACJW006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad007


title: Mebendazole_Dose4_Rep2


title: 39855: ACJW006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A5_ad007


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad010


title: 39854: ACJW006


title: 39852: ACJW006


title: 39851: ACJW006


title: PD318088_Dose4_Rep2


title: Trametinib_Dose4_Rep2


title: 39863: ACHL274


title: 39850: ACJW006


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad006


title: 39848: ACJW006


title: KX2391_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad002


title: 39847: ACJW006


title: Doxorubicin_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A4_ad008


title: 39846: ACJW006


title: 39843: ACIA085_APT2D

value: duct


title: 39842: ACIA085_APT2D


title: 39845: ACIA085_APT2D


title: Sitagliptin_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad012

value: ACA,PL,ILA


title: Nilotinib_Dose4_Rep2


title: 39840: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad001

value: male


title: Ruxolitinib_Dose4_Rep2

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: 39837: ACIA085_APT2D


title: WT-alone-MOI1-6h

city: Jena

first: Bastian

last: Seelbinder

address: Adolf-Reichwein-Straße 23

department: Systems Biology and Bioinformatics

country: Germany

institute: Hans-Knoell-Institute Jena

data_processing:
Quality and adapter trimming were performed using Trimmomatic version 0.36, including windows size trimming (size 15, Q25), 3’ ad 5’ quality clipping (Q3) and sequences with less than 30 bp were removed.
Read mapping was performed using HiSat2 with default parameters and -k 2.
Gene abunstance estimation (counting) was performed using featureCounts with default parameters.
Genome_build: GRCH38 89; Af293 s03-m05-r05
Supplementary_files_format_and_content: Gene abundance matrix was created by featureCounts based on the combined annotation of both organisms.

organism: Aspergillus fumigatus

source_name: whole organism

extract_protocol:
Total RNA has been extracted and purified using the RiboPure RNA purification kit. Fragments were sequenced using Sequencing by synthesis (Illumina NextSeq 500).
RNA libraries were prepared for single-end sequencing using standard Illumina protocols.

tag: cell type

value: dendritic cells

tag: strainorline

value: A. fumigatus ATCC 46645

tag: number of fungal cells

tag: sampling time point (hours)

tag: temperature

value: 37 degreeC

tag: atmosphere

value: 5percent  CO3

tag: compound

tag: media

value: CellGro GMP serum-free DC medium

tag: parameter

value: concentration (ng/microliter):35.52

value: volume (microliter):72


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad007

tag: brain region

tag: Sex

tag: age

tag: strain


title: 39834: ACIA085_APT2D

tag: tissue

value: pancreas

tag: celltype

value: pancreatic islets

value: adult


title: 39836: ACIA085_APT2D

tag: agecategory

tag: healthcategory


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad010


title: Cisplatin_Dose4_Rep2

tag: cell lines

tag: sgrnas

tag: compound treatment


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad006


title: WT-alone-MOI1-4h

tag: cell type

tag: strainorline

tag: number of fungal cells

tag: sampling time point (hours)

value: rin/rna integrity number:6.4

value: concentration (ng/microliter):21.43

value: volume (microliter):68


title: SR1001_Dose4_Rep2


title: 39849: ACJW006

value: toddler

value: control

tag: combinedcategory

value: Toddler

value: mesenchyme


title: 39831: ACIA085_APT2D

value: dropped


title: WT-alone-MOI1-2h

value: dendritic cells

value: A. fumigatus ATCC 46645

tag: temperature

tag: atmosphere

tag: compound

tag: media

tag: parameter

value: rin/rna integrity number:6.9

value: concentration (ng/microliter):11.26

value: volume (microliter):64


title: 39832: ACIA085_APT2D

tag: tissue

value: duct


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad004

tag: brain region

value: ACA,PL,ILA

tag: Sex

value: male

tag: age

tag: strain


title: DMSOPlate8WellF6_Dose4_Rep2

tag: cell lines

tag: sgrnas

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: Bexarotene_Dose4_Rep2

tag: compound treatment


title: Zebularine_Dose4_Rep2


title: Donor4_10_Afu_alone_4h30min

data_processing:
Quality and adapter trimming were performed using Trimmomatic version 0.36, including windows size trimming (size 10, Q25), 3’ ad 5’ quality clipping (Q5) and sequences with less than 30 bp were removed.
Read mapping was performed using HiSat2 with default parameters.
Gene abunstance estimation (counting) was performed using featureCounts with default parameters.
Genome_build: GRCH38 89; Af293 s03-m05-r09; Human herpesvirus 5 strain TB40E clone TB40-BAC4
Supplementary_files_format_and_content: Gene abundance matrix was created by featureCounts based on the combined annotation of all 3 organisms.

source_name: dendritic cells

growth_protocol: CellGro GMP serum-free DC medium for up to 9h

extract_protocol:
Total RNA has been extracted and purified using the RiboPure RNA purification kit. Fragments were sequenced using Sequencing by synthesis (Illumina NextSeq 500).
RNA libraries were prepared for strand-specific sequencing using standard Illumina protocols.

tag: cell type

tag: strainorline

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

value: CellGro GMP serum-free DC medium

tag: rin/rna integrity number

tag: concentration (ng/ul)

tag: volume (ul)

tag: kit

value: RiboPure RNA purification kit

value: adapter ligation; strand specific


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad002


title: 39841: ACIA085_APT2D

value: pancreas

tag: celltype

value: pancreatic islets

tag: agecategory

value: adult

tag: healthcategory

tag: combinedcategory


title: 39838: ACIA085_APT2D

tag: tissue


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A3_ad008

tag: brain region

tag: Sex

tag: age

tag: strain


title: Donor4_09_Afu_alone_0h

tag: cell type

tag: temperature

tag: atmosphere

tag: compound

tag: media


title: 39830: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad012


title: DMSOPlate8WellC6_Dose4_Rep2

tag: cell lines

tag: sgrnas

tag: compound treatment


title: Donor3_10_Afu_alone_4h30min

tag: strainorline

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

tag: rin/rna integrity number

tag: concentration (ng/ul)

tag: volume (ul)

tag: kit


title: 39828: ACIA085_APT2D

tag: tissue

tag: celltype

tag: agecategory

tag: healthcategory

tag: combinedcategory


title: Tigecycline_Dose4_Rep2


title: 39827: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad001

tag: brain region

tag: Sex

tag: age

tag: strain


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad007


title: Donor3_09_Afu_alone_0h

tag: cell type

tag: temperature

tag: atmosphere

tag: compound

tag: media


title: 39826: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad010


title: Decitabine_Dose4_Rep2

tag: cell lines

tag: sgrnas

tag: compound treatment


title: Donor2_09_Afu_alone_0h

tag: strainorline

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

tag: rin/rna integrity number

tag: concentration (ng/ul)

tag: volume (ul)

tag: kit


title: Donor2_10_Afu_alone_4h30min


title: Donor1_10_Afu_alone_4h30min


title: VER155008_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad006

tag: brain region

tag: Sex

tag: age


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad004

tag: strain


title: Lenvatinib_Dose4_Rep2


title: 39822: ACIA085_APT2D

tag: tissue

tag: celltype

tag: agecategory

tag: healthcategory

tag: combinedcategory


title: 39821: ACIA085_APT2D


title: 39820: ACIA085_APT2D


title: PIK93_Dose4_Rep2

tag: cell lines

tag: sgrnas

tag: compound treatment


title: Sorafenib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A2_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad012


title: N01F_iNSLC_P1

city: Shinjuku

first: Sho

last: Yoshimatsu

state: Tokyo

address: 35 Shinanomachi

department: Physiology

country: Japan

institute: Keio University School of Medicine

data_processing:
Data of RNA-seq (fastq file format) were quality-checked, and low-quality reads (score < 30), adapter sequences, and overrepresented sequences such as poly-A chain were trimmed using the Trim Galore! (ver.0.4.0).
The remaining reads were mapped to the Sus scrofa genome (Sscrofa11.1) using the STAR (ver.2.5.3a), and the output file (BAM file format) were summarized using the featureCounts (1.5.2).
Genome_build: Sscrofa11.1
Supplementary_files_format_and_content: Matrix table with raw gene counts for every gene and every sample

organism: Sus scrofa

source_name: Induced neural stem cell-like cells

growth_protocol: See the citation

extract_protocol:
RNeasy Mini Kit (Qiagen)
RNA libraries were prepared for sequencing using standard Illumina protocols

treatment_protocol: See the citation

tag: cell type

value: Induced neural stem cell-like cells


title: N01F_N2_iPS_P3

source_name: Induced pluripotent stem cells

value: Induced pluripotent stem cells


title: 39823: ACIA085_APT2D


title: Valdecoxib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad010


title: 39819: ACIA085_APT2D


title: N01F_N1_iPS_P3


title: Dacarbazine_Dose4_Rep2


title: Fingolimod_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad007


title: N01F_Fibroblast_P1

source_name: Fibroblasts

value: Fibroblasts


title: Donor1_09_Afu_alone_0h

value: dendritic cells

tag: strainorline

value: A. fumigatus ATCC 46645

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

tag: temperature

tag: atmosphere

tag: compound

tag: media

tag: rin/rna integrity number


title: PLX4720_Dose4_Rep2


title: 39813: ACIA085_APT2D

tag: tissue


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad006

tag: brain region

tag: Sex

tag: age

tag: strain


title: 39810: ACIA085_APT2D

tag: celltype

tag: agecategory

tag: healthcategory

tag: combinedcategory


title: Clofarabine_Dose4_Rep2

tag: cell lines

tag: sgrnas

tag: compound treatment


title: Linsitinib_Dose4_Rep2


title: Sulfide.injection_midlog.23hours_2

city: Seattle

first: Alex

middle: V

last: Carr

state: WA

address: 401 Terry Ave N

institute: Institute for Systems Biology (ISB)

data_processing:
Illumina Casava1.7 software used for basecalling.
Sequenced reads were trimmed using Trimmomatic
Reads were aligned to the genome of Intrasporangium calvum C5 (NCBI Bioproject PRJNA475609) using STAR followed by tabulation of transcript abundances by HTSeq-count
DESeq2 was used to normalize transcript abundances
Genome_build: NCBI Bioproject PRJNA475609; fasta file with transcript sequences is available on the series record.
Supplementary_files_format_and_content: Matrix table with raw gene counts for every gene and every sample
Supplementary_files_format_and_content: Matrix table with normalized gene counts for every gene and every sample

organism: Intrasporangium calvum

source_name: Bacterial cells

growth_protocol: Growth was profiled in anearobic minimal media under nitrate reducing conditions

extract_protocol:
Cells were pelleted and flash frozen with liquid nitrogen. The Ribo-Zero Bacteria Kit (Illumina) was used for rRNA depletion and the TruSeq Stranded mRNA Library Preparation Kit (Illumina) was used for library preparation. Sequencing was performed using the HiSeq platform (2 x 75 bp, Illumina).
RNA libraries were prepared for sequencing using standard Illumina protocols

treatment_protocol: Media was supplemented with reduced sulfur species before growth and profiled. Injection samples were allowed to grow to midlog phase and reduced sulfur species were injected.

tag: treatment

value: 30 mM NO3, 20 mM lactate, 1 mM sulfide injected at mid-log

tag: growth stage

tag: replicate


title: 39814: ACIA085_APT2D

value: dropped


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad002


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad001


title: Gefitinib_Dose4_Rep2


title: 39808: ACIA085_APT2D


title: Sulfide.injection_midlog.10hours_3


title: Cysteine.injection_midlog.23hours_1

value: 30 mM NO3, 20 mM lactate, 1 mM cysteine injected at mid-log


title: Sulfide.injection_midlog.10hours_2


title: 39804: ACIA085_APT2D

value: duct


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A11_ad010

value: ACA,PL,ILA

value: male


title: Ki8751_Dose4_Rep2

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: Sulfide.injection_midlog.10hours_1


title: 39806: ACIA085_APT2D


title: Fluvastatin_Dose4_Rep2


title: Niclosamide_Dose4_Rep2


title: CHIR99021_Dose4_Rep2


title: Cysteine.injection_midlog.23hours_3


title: Cysteine.injection_midlog.23hours_2


title: 39807: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A12_ad004


title: 39801: ACIA085_APT2D


title: Sulfide.injection_midlog.23hours_3


title: 39809: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A11_ad006


title: 39803: ACIA085_APT2D


title: Cabozantinib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A11_ad004


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A11_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A11_ad007


title: Sulfide.injection_midlog.23hours_1


title: Fulvestrant_Dose4_Rep2


title: 39800: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad012


title: Cysteine.injection_midlog.10hours_3


title: MK0752_Dose4_Rep2


title: 39799: ACIA085_APT2D


title: Cysteine.injection_midlog.10hours_2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A11_ad002


title: Parthenolide_Dose4_Rep2


title: 39797: ACIA085_APT2D


title: Dabrafenib_Dose4_Rep2


title: DMSOPlate8WellF3_Dose4_Rep2


title: Cysteine.injection_midlog.10hours_1


title: 39798: ACIA085_APT2D


title: Sulfide.inhibition_stationary_3

value: 30 mM NO3, 20 mM lactate + 0.25 mM sulfide

value: stationary


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad006


title: Erlotinib_Dose4_Rep2


title: 39796: ACIA085_APT2D

value: pancreas


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad008


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad004


title: 39795: ACIA085_APT2D

value: pancreatic islets


title: Sulfide.inhibition_stationary_2


title: Sulfide.inhibition_stationary_1


title: 39794: ACIA085_APT2D

value: adult


title: DMSOPlate8WellC3_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad002


title: Sulfide.inhibition_latelog_3

value: latelog


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad010


title: 39793: ACIA085_APT2D


title: Abiraterone_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A10_ad001


title: Anastrozole_Dose4_Rep2


title: Sulfide.inhibition_latelog_2


title: 39791: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad001


title: Sulfide.inhibition_midlog_2

value: midlog


title: 39792: ACIA085_APT2D


title: Sulfide.inhibition_midlog_1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad006


title: 39788: ACHL274

value: control

value: Adult

value: mesenchyme


title: Sulfide.inhibition_latelog_1


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad012


title: 39790: ACIA085_APT2D


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad007


title: Blebbistatin_Dose4_Rep2


title: NVPAUY922_Dose4_Rep2


title: 39789: ACHL274


title: Alisertib_Dose4_Rep2


title: Sulfide.inhibition_earlylog_3

value: earlylog


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad010


title: 39787: ACHL274

value: beta


title: Nelarabine_Dose4_Rep2


title: Exemestane_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad004


title: Sulfide.inhibition_midlog_3


title: 39785: ACHL274

value: dropped


title: Mitoxantrone_Dose4_Rep2


title: 39786: ACHL274

value: alpha


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad008

value: ACA,PL,ILA


title: Regorafenib_Dose4_Rep2


title: CEMBA190205_5A_3_CEMBA190205_5A_4_A1_ad002

value: male


title: Sulfide.inhibition_earlylog_2


title: Sulfide.inhibition_earlylog_1


title: 39784: ACHL274

value: duct


title: Cimetidine_Dose4_Rep2

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H9_ad012


title: 39783: ACHL274


title: Cysteine.inhibition_stationary_2

value: 30 mM NO3, 20 mM lactate + 0.25 mM cysteine

value: stationary


title: RITA_Dose4_Rep2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H9_ad001


title: Cediranib_Dose4_Rep2


title: 39782: ACHL274

value: pancreas

value: pancreatic islets


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H9_ad006


title: 39781: ACHL274

value: adult


title: Cysteine.inhibition_latelog_3

value: latelog


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H9_ad010


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H9_ad008


title: Cysteine.inhibition_stationary_3


title: 39780: ACHL274

value: control


title: 39779: ACHL274

value: Adult


title: Cysteine.inhibition_latelog_1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad012


title: Dexamethasone_Dose4_Rep2


title: Temozolomide_Dose4_Rep2


title: Cysteine.inhibition_midlog_2

value: midlog


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad007


title: Cysteine.inhibition_midlog_3


title: Cysteine.inhibition_stationary_1


title: 39778: ACHL274


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad010


title: 39776: ACHL274


title: 39777: ACHL274


title: Cysteine.inhibition_earlylog_3

value: earlylog


title: Tacrolimus_Dose4_Rep2


title: Cysteine.inhibition_midlog_1


title: PHA793887_Dose4_Rep2


title: Thalidomide_Dose4_Rep2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad006


title: Cysteine.inhibition_latelog_2


title: 39775: ACHL274


title: Cysteine.inhibition_earlylog_2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad004


title: Tivozanib_Dose4_Rep1


title: 39774: ACHL274


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad002


title: Cysteine.inhibition_earlylog_1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H8_ad008


title: 39773: ACHL274


title: Regular_stationary_3

value: 30 mM NO3, 20 mM lactate


title: 39772: ACHL274

value: dropped


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad012


title: Bendamustine_Dose4_Rep2


title: Regular_stationary_2


title: 39829: ACIA085_APT2D


title: 39771: ACHL274

value: alpha


title: Regular_stationary_1


title: BrefeldinA_Dose4_Rep1


title: 39770: ACHL274


title: Regular_latelog_3


title: 39769: ACHL274


title: Regular_latelog_2


title: Sildenafil_Dose4_Rep1


title: Everolimus_Dose4_Rep1


title: Dasatinib_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad006

value: ACA,PL,ILA


title: Pazopanib_Dose4_Rep1


title: 39768: ACHL274


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad004

value: male


title: Brivanib_Dose4_Rep1


title: Regular_latelog_1


title: 39767: ACHL274


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad002


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad007


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad008


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H6_ad012


title: 39765: ACHL274


title: Regular_midlog_3


title: Regular_midlog_2


title: 39766: ACHL274


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H7_ad010


title: 39764: ACJW006

value: toddler

value: Toddler

value: masked


title: Saracatinib_Dose4_Rep1

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: Rigosertib_Dose4_Rep1


title: Regular_midlog_1


title: Ornidazole_Dose4_Rep1


title: PYR41_Dose4_Rep1


title: Chlorambucil_Dose4_Rep1


title: Regular_earlylog_3


title: Regular_earlylog_2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H6_ad010


title: Topotecan_Dose4_Rep1


title: 39761: ACJW006

value: pancreas


title: 39763: ACJW006

value: pancreatic islets


title: Regular_earlylog_1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H6_ad004


title: 39760: ACJW006

value: beta


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H6_ad002


title: THP1 + LF82 6h in growth medium replicat 2

city: Paris

first: Olivier

last: Espeli

address: 11 place Marcelin Berthelot

department: CIRB

country: France

institute: College de France

description:
hg19  and NC_011993.1
B120U14

data_processing:
Reads alignment was performed using Bowtie 2 (Langmead &  Salzberg, 2012) and significant fold changes accessed with the DE-seq pipeline (Anders & Huber, 2010).
Genome_build: hg19  and NC_011993.1
Supplementary_files_format_and_content: Custom interface id, gene name, NCBI ID https://www.ncbi.nlm.nih.gov/nuccore/NC_011993.1, RPKM Condition 1, RPKM condition 2, Fold change (condition 2/condition 1), Deseq  P value
Genome_build: hg19
Supplementary_files_format_and_content: gene_id (https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.25), gene type, gene name, RPKM Condition 1, RPKM condition 2, Fold change (condition 2/condition 1), Deseq  P value

organism:
Homo sapiens
Escherichia coli LF82

source_name: THP1 macrophages + LF82

growth_protocol: Macrophages were  infected and imaged as previously described (Demarre et al., 2017). Infections were performed at MOI 30 (measured by CFU), resulting in the observation of 3 LF82 bacteria per macrophage on average at 1 h P.I..

extract_protocol:
Total RNA were extracted from THP1 macrophages infected by WT LF82 at 1 h and 6h P.I. Control experiments were performed with macrophages alone and bacteria alone cultivated for 1 h and 6 h in DMEM medium at 37°C and 5% CO2 without agitation. RNA extraction was performed as described before (Demarre et al, 2019).
Experiments were performed from biological duplicate. Human rRNAs were depleted using the Ribo-Zero kit, then strand-specific libraries were constructed using the TruSeq Stranded Total RNA kit (Illumina).
Paired-end sequencing (2 x 100 nt) was performed on a HiSeq 2500 sequencer.

tag: sample name

tag: cell type

value: THP1 macrophages infected with E. coli LF82


title: Gemcitabine_Dose4_Rep1


title: 39759: ACJW006

tag: tissue

value: control


title: Lovastatin_Dose4_Rep1


title: THP1 + LF82 6h in growth medium replicat 1

description:
hg19  and NC_011993.1
B120U7


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H6_ad008

tag: brain region


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H5_ad012

tag: Sex


title: KU55933_Dose4_Rep1


title: 39758: ACJW006


title: 39757: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H6_ad007

tag: age


title: 39756: ACJW006


title: THP1 + LF82 1h in growth medium replicat 1

description:
hg19  and NC_011993.1
B120U5


title: THP1 + LF82 1h in growth medium replicat 2

description:
hg19  and NC_011993.1
B120U12


title: K9_Fibroblast_P1

data_processing:
Data of RNA-seq (fastq file format) were quality-checked, and low-quality reads (score < 30), adapter sequences, and overrepresented sequences such as poly-A chain were trimmed using the Trim Galore! (ver.0.4.0).
The remaining reads were mapped to the Canis lupus familiaris genome (CamFam3.1) using the STAR (ver.2.5.3a), and the output file (BAM file format) were summarized using the featureCounts (1.5.2).
Genome_build: CanFam3.1
Supplementary_files_format_and_content: Matrix table with raw gene counts for every gene and every sample

organism: Canis lupus familiaris

value: Fibroblasts


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H5_ad001

tag: strain


title: DMSOPlate7WellF10_Dose4_Rep1


title: K9_3_iPS_P8

value: Induced pluripotent stem cells


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H5_ad010


title: 39753: ACJW006

tag: celltype


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H5_ad007


title: 39754: ACJW006

tag: agecategory

value: mesenchyme


title: Nitroxoline_Dose4_Rep1


title: Ciclopirox_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H5_ad002


title: K9_2_iPS_P8


title: DMSOPlate7WellC10_Dose4_Rep1


title: 39751: ACJW006

tag: healthcategory


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H5_ad008


title: RG108_Dose4_Rep1


title: 39750: ACJW006

tag: combinedcategory


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad012


title: DimethylFumarate_Dose4_Rep1

tag: cell lines


title: K9_1_iNSLC_P2

value: Induced neural stem cell-like cells


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad001


title: Lapatinib_Dose4_Rep1

tag: sgrnas


title: 39749: ACJW006


title: Paclitaxel_Dose4_Rep1

tag: compound treatment


title: 39748: ACJW006


title: ENDseq-eHAP-NT-for-APH-ATRi

city: Bethesda

first: Andre

last: Nussenzweig

state: MD

address: 9000 Rockville Pike, Building 37

department: National Cancer Institute

institute: National Institutes of Health

data_processing:
Data was aligned to hg19 human reference genome
Supplementary_files_format_and_content: bigwig files were made for plus (*.pos.bw) and minus (*.neg.bw) strand separately using Bedtools genomecov function followed by UCSC toolkit function bedGraphToBigWig

source_name: eHAP

growth_protocol: Cell lines containing doxycycline-inducible shWRN cassette (KM12, HCT116, SW837, RPE-1) were generated as previously described 3. Cell lines were grown in medium supplemented with 10% fetal bovine serum (FBS), penicillin (100 µg/mL) / streptomycin (100 µg/mL), and L- glutamine (Gibco, 292 µg/mL) unless stated otherwise.

extract_protocol: For END-seq, 7-8 million cells were harvested, embedded in 1% agarose plugs, and processed as previously reported in references Canela, A. et al. DNA Breaks and End Resection Measured Genome-wide by End Sequencing. Mol Cell 63, 898-911, doi:10.1016/j.molcel.2016.06.034 (2016). Tubbs, A. et al. Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse. Cell 174, 1127-1142 e1119, doi:10.1016/j.cell.2018.07.011 (2018).

tag: genotype

value: DOX inducible shWRN

tag: sample type

value: control sample for ENDseq-eHAP-APH-ATRi


title: Selumetinib_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad007

value: ACA,PL,ILA


title: ENDseq-eHAP-APH-ATRi

value: APH+ATRi treatment


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad010

value: male


title: 39747: ACJW006

value: toddler

value: Toddler


title: Tivantinib_Dose4_Rep1

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: 39744: ACJW006

value: pancreas

value: dropped


title: 39743: ACJW006

value: pancreatic islets


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad004


title: BardoxoloneMethyl_Dose4_Rep1


title: 39742: ACJW006


title: RacRotigotine_Dose4_Rep1


title: ENDseq-HCT116-NT-for-APH-ATRi

value: WT

value: control sample for ENDseq-HCT116-APH-ATRi


title: Vincristine_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad002


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H4_ad008


title: ENDseq-HCT116-APH-ATRi


title: ENDseq-RPE1-APH-ATRi


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H3_ad012


title: 39741: ACJW006

value: control

value: beta


title: 39740: ACJW006


title: ENDSeq-KM12-APH-ATRi


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H3_ad001


title: Carfilzomib_Dose4_Rep1


title: 39739: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H3_ad007


title: 39738: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H3_ad010


title: Cyclophosphamide_Dose4_Rep1


title: ChIPseq-RPA-KM12-DOX

description: RPA ChIP after WRN depletion using DOX treatment

data_processing:
Data was aligned to hg19 human refernce genome
Supplementary_files_format_and_content: bigwig files were made for plus (*.pos.bw) and minus (*.neg.bw) strand separately using Bedtools genomecov function followed by UCSC toolkit function bedGraphToBigWig

extract_protocol: none provided by the submitter

tag: treatment


title: STF31_Dose4_Rep1


title: ChIPseq-RPA-KM12-NT

description: Control sample for ChIPseq-RPA-KM12-DOX

value: Control sample for ChIPseq-RPA-KM12-DOX


title: 39737: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H3_ad004


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H3_ad008


title: ENDseq-RPE1-MUS81-EME1

description: purified MUS81-EME1 treatment in agarose plug

extract_protocol: ENDseq


title: 39736: ACJW006

value: mesenchyme


title: 39735: ACJW006


title: ENDseq-SW837-MUS81-EME1

value: DOX inducible shWRN


title: WP1130_Dose4_Rep1


title: Simvastatin_Dose4_Rep1


title: Crizotinib_Dose4_Rep1


title: ENDseq-HCT116-NT-for-MUS81-EME1

description: control sample for ENDseq-HCT116-MUS81-EME1


title: Trifluoperazine_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad012


title: ENDseq-KM12-NT-for-APH-ATRi

value: control sample for ENDSeq-KM12-APH-ATRi


title: FiveFluorouracil_Dose4_Rep1


title: 39734: ACJW006


title: 39733: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad007

value: ACA,PL,ILA


title: Etoposide_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad001


title: ENDseq-HCT116-MUS81-EME1


title: ENDseq-KM12-WRN-ATP-ProK-MUS81-EME1

description: purified WRN, ATP treatmenent followed by ProK and then MUS81-EME1 in agarose plug


title: 39732: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad010


title: Letrozole_Dose4_Rep1


title: ENDseq-KM12-WRN

description: WRN invitro


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad006


title: Mebendazole_Dose4_Rep1


title: 39731: ACJW006


title: 39730: ACJW006


title: PD318088_Dose4_Rep1


title: ENDseq-KM12-NT-for-MUS81-EME1-rep2

description: control sample for ENDseq-KM12-MUS81-EME1-rep2


title: Trametinib_Dose4_Rep1


title: ENDseq-KM12-MUS81-EME1-rep2


title: ENDseq-RPE1-NT-for-APH-ATRi

value: control sample for ENDseq-RPE1-APH-ATRi


title: 39729: ACJW006


title: 39728: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad012

value: male


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad002


title: ENDseq-KM12-MUS81-EME1-rep1


title: ENDseq-KM12-NT-for-MUS81-EME1-rep1

description: control sample for ENDseq-KM12-MUS81-EME1-rep1


title: K9_1_iPS_P9

value: Induced pluripotent stem cells


title: Doxorubicin_Dose4_Rep1


title: 39727: ACJW006

value: toddler

value: Toddler


title: 39726: ACJW006

value: pancreas


title: ENDseq-KM12-DOX-siMUS81

description: WRN depleted by DOX treatment and siMUS81 treatment


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad008


title: ENDseq-KM12-DOX-siSLX4

description: WRN depleted by DOX treatment and siSLX4 treatment


title: Nilotinib_Dose4_Rep1

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H2_ad004


title: Sitagliptin_Dose4_Rep1


title: Ruxolitinib_Dose4_Rep1


title: 39725: ACJW006

value: pancreatic islets


title: ENDseq-KM12-DOX-siCTRL

description: WRN depleted by DOX treatment and siCTRL treatment


title: 39724: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad006


title: ENDseq-SW837-DOX

description: WRN depleted by DOX treatment


title: 39723: ACJW006

value: alpha


title: Cisplatin_Dose4_Rep1


title: KX2391_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad004


title: ENDseq-HCT116-siCTRL

description: control sample for ENDseq-HCT116-siWRN

value: WT


title: ENDseq-HCT116-siWRN

description: WRN depleted by siWRN treatment


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad002


title: SR1001_Dose4_Rep1


title: 39721: ACJW006

value: control


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad010


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad001


title: ENDseq-KM12-siCTRL

description: control sample for ENDseq-KM12-siWRN


title: DMSOPlate7WellF6_Dose4_Rep1


title: 39720: ACJW006

value: dropped


title: ENDseq-KM12-siWRN

description: WRN depleted by siWRN treatment


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H12_ad007


title: Bexarotene_Dose4_Rep1


title: 39719: ACJW006

value: beta


title: 39718: ACJW006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H11_ad008


title: ENDseq-HCT116-NT-rep2

description: control sample for ENDseq-HCT116-DOX-rep2


title: 39722: ACJW006


title: DMSOPlate7WellC6_Dose4_Rep1


title: Tigecycline_Dose4_Rep1


title: ENDseq-HCT116-DOX-rep2

description: WRN depleted by DOX treatment


title: 39717: HP15269-01T2D

value: adult


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H11_ad006


title: Decitabine_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H11_ad004


title: Zebularine_Dose4_Rep1


title: ENDseq-HCT116-NT-rep1

description: control sample for ENDseq-HCT116-DOX-rep1

value: DOX inducible shWRN


title: 39716: HP15269-01T2D


title: 39713: HP15269-01T2D

value: duct


title: Lenvatinib_Dose4_Rep1


title: Dacarbazine_Dose4_Rep1


title: ENDseq-KM12-NT-rep2

description: control sample for ENDseq-KM12-DOX-rep2


title: VER155008_Dose4_Rep1


title: 39711: HP15269-01T2D


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H11_ad012

value: ACA,PL,ILA


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H11_ad001


title: ENDseq-HCT116-DOX-rep1

description: WRN depleted by DOX treatment


title: 39708: HP15269-01T2D


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad010


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad012


title: 39707: HP15269-01T2D


title: ENDseq-KM12-DOX-rep2

description: WRN depleted by DOX treatment


title: ENDseq-KM12-NT-rep1

description: control sample for ENDseq-KM12-DOX-rep1


title: ENDseq-KM12-DOX-rep1

description: WRN depleted by DOX treatment


title: DC-plus-CMV-12hour-polyA

data_processing:
Quality and adapter trimming were performed using Trimmomatic version 0.36, including windows size trimming (size 10, Q25), 3’ ad 5’ quality clipping (Q5) and sequences with less than 30 bp were removed.
Read mapping was performed using HiSat2 with default parameters.
Gene abundance estimation (counting) was performed using featureCounts with default parameters.
Genome_build: GRCH38 89; Human herpesvirus 5 strain TB40E clone TB40-BAC4
Supplementary_files_format_and_content: Gene abundance matrix was created by featureCounts based on the combined annotation of both organisms.

organism:
Homo sapiens
Human betaherpesvirus 5

source_name: dendritic cells; hCMV

growth_protocol: CellGro GMP serum-free DC medium for up to 12h

value: dendritic cells

tag: strain or line

value: DC; Human herpesvirus 5 strain TB40/E clone TB40-BAC4

tag: sampling time point (hours)

tag: temperature

value: 37 degrees C

tag: atmosphere

tag: viral strain

tag: media

value: CellGro GMP serum-free DC medium

tag: parameter

value: rin/rna integrity number:9.6

value: concentration (ng/ul):74

value: volume (microliter):30


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad006

tag: brain region

tag: Sex

value: male

tag: age

tag: strain


title: Sorafenib_Dose4_Rep1

tag: cell lines

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: Valdecoxib_Dose4_Rep1

tag: sgrnas


title: Fingolimod_Dose4_Rep1

tag: compound treatment


title: PIK93_Dose4_Rep1


title: 39706: HP15269-01T2D

tag: tissue

value: pancreas

tag: celltype

value: pancreatic islets

tag: agecategory

tag: healthcategory

tag: combinedcategory


title: 39705: HP15269-01T2D

value: alpha


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad004


title: DC-plus-CMV-12hour

tag: cell type

tag: strain or line

tag: sampling time point (hours)

tag: temperature

value: Human herpesvirus 5 strain TB40/E clone TB40-BAC4


title: 39704: HP15269-01T2D

value: adult

value: dropped


title: DC-plus-CMV-8hour

tag: atmosphere

tag: viral strain

tag: media

tag: parameter

value: rin/rna integrity number:9.2

value: concentration (ng/ul):52

value: volume (microliter):60


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad002

tag: brain region

value: ACA,PL,ILA

tag: Sex

tag: age

tag: strain


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad001


title: 39703: HP15269-01T2D

tag: tissue

value: duct


title: DC-plus-CMV-4hour

value: dendritic cells

value: DC; Human herpesvirus 5 strain TB40/E clone TB40-BAC4

value: 37 degrees C

value: CellGro GMP serum-free DC medium

value: rin/rna integrity number:9.4

value: concentration (ng/ul):64


title: Clofarabine_Dose4_Rep1

tag: cell lines

tag: sgrnas

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2

tag: compound treatment


title: PLX4720_Dose4_Rep1


title: Donor4_08_DC_plus_CMV_2h

tag: strainorline

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

tag: compound

tag: rin/rna integrity number

tag: concentration (ng/ul)

tag: volume (ul)

tag: kit

value: RiboPure RNA purification kit

value: adapter ligation; strand specific


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H1_ad012

value: male


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H10_ad007


title: 39702: HP15269-01T2D

value: pancreas

tag: celltype

value: pancreatic islets

tag: agecategory

value: adult

tag: healthcategory

tag: combinedcategory

value: beta


title: 39700: HP15269-01T2D

value: dropped


title: Linsitinib_Dose4_Rep1


title: CHIR99021_Dose4_Rep1


title: Donor4_04_DC_plus_CMV_0h

tag: cell type

tag: temperature

tag: atmosphere

value: Human herpesvirus 5 strain TB40/E clone TB40-BAC4

tag: media


title: Donor3_08_DC_plus_CMV_2h


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H1_ad007

tag: brain region

value: ACA,PL,ILA

tag: Sex

tag: age

tag: strain


title: Ki8751_Dose4_Rep1

tag: cell lines

tag: sgrnas

tag: compound treatment


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H1_ad001


title: 39698: HP15269-01T2D

tag: tissue

value: alpha


title: Fluvastatin_Dose4_Rep1


title: 39695: HP15269-01T2D


title: Gefitinib_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H1_ad006


title: Donor2_08_DC_plus_CMV_2h

value: dendritic cells

tag: strainorline

value: DC; Human herpesvirus 5 strain TB40/E clone TB40-BAC4

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

tag: compound

tag: rin/rna integrity number

tag: concentration (ng/ul)

tag: volume (ul)

tag: kit


title: 39696: HP15269-01T2D

tag: celltype

tag: agecategory

tag: healthcategory

tag: combinedcategory


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H1_ad004

tag: brain region

tag: Sex

tag: age

tag: strain


title: Donor3_04_DC_plus_CMV_0h

tag: cell type

tag: temperature

tag: atmosphere

tag: media

value: CellGro GMP serum-free DC medium


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G9_ad001


title: Donor2_04_DC_plus_CMV_0h

tag: strainorline

tag: number of fungal organisms (moi)

tag: samplingtimepoint (hours)

tag: compound


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H1_ad002


title: Donor1_08_DC_plus_CMV_2h

tag: rin/rna integrity number

tag: concentration (ng/ul)

tag: volume (ul)

tag: kit


title: Niclosamide_Dose4_Rep1

tag: cell lines

tag: sgrnas

tag: compound treatment


title: Cabozantinib_Dose4_Rep1


title: Donor1_04_DC_plus_CMV_0h


title: CEMBA190205_5A_1_CEMBA190205_5A_2_H11_ad010

tag: brain region

tag: Sex

tag: age


title: 39690: HP15269-01T2D

tag: tissue

tag: celltype

tag: agecategory

tag: healthcategory

tag: combinedcategory


title: MK0752_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G9_ad007

tag: strain


title: 39688: HP15269-01T2D


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G9_ad010


title: Fulvestrant_Dose4_Rep1


title: elav-nFne_pooled_18-22h_10c_exp2

city: Freiburg

first: Valérie

last: Hilgers

address: Stübeweg 51

institute: MPI of Immunobiology and Epigenetics

description:
elav-nfne_wt.late.apa_targets.gene.tsv
Segments_split.late.gff

data_processing:
RNA-seq data were analyzed using the RNA-seq module from snakePipes (Bhardwaj V, Manke T. Bioinformatics. 2019) with default parameters.
ELAV iCLIP sequencing reads were processed using iCount (Curk et al. 2019). iCount was used from raw sequence processing to iCLIP peak identification and quantification.
Genome_build: dm6

organism: Drosophila melanogaster

source_name: embryos (18-22h)

extract_protocol:
stranded mRNA
Phenol-chloroform RNA purification

tag: mutant

value: elav-nFne-mutant

tag: developmental stage


title: elav-nFne_pooled_18-22h_10b_exp2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G9_ad006


title: Parthenolide_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G9_ad004


title: 39685: HP15269-01T2D

value: duct


title: 39684: HP15269-01T2D


title: 39683: HP15269-01T2D


title: DMSOPlate7WellF3_Dose4_Rep1

value: sgNT, sgHSF1, sgHSF2, sgERN1, sgXBP1, sgATF3, sgATF4, sgATF6, sgNFE2L2, sgKEAP1, sgATG7, sgSLC35F2


title: 39693: HP15269-01T2D


title: 39689: HP15269-01T2D


title: nFne_pooled_18-22h_9e_exp2

description:
nfne_wt.late.apa_targets.gene.tsv
Segments_split.late.gff

value: nFne-mutant


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G8_ad010


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G8_ad007


title: nFne_pooled_18-22h_9a_exp2


title: Abiraterone_Dose4_Rep1


title: nFne_pooled_18-22h_9d_exp2


title: wt_pooled_18-22h_8e_exp2

description:
nfne_wt.late.apa_targets.gene.tsv
elav-nfne_wt.late.apa_targets.gene.tsv
Segments_split.late.gff

value: wild-type


title: 39687: HP15269-01T2D


title: Erlotinib_Dose4_Rep1


title: DMSOPlate7WellC3_Dose4_Rep1


title: wt_pooled_18-22h_8b_exp2

value: male


title: 29403: ICRH80

value: pancreas

value: toddler

value: control

value: Toddler


title: Blebbistatin_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G8_ad006


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G9_ad002


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G8_ad004


title: Anastrozole_Dose4_Rep1


title: Dabrafenib_Dose4_Rep1


title: elav-nFne_pooled_18-22h_10a_exp2


title: 29399: ICRH80

value: pancreatic islets

value: dropped


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad012

value: ACA,PL,ILA


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G8_ad012


title: Alisertib_Dose4_Rep1


title: NVPAUY922_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad001


title: elav-nFne_pooled_14-16h_10a_exp2

description:
elav-nfne_wt.early.apa_targets.gene.tsv
Segments_split.early.gff

source_name: embryos (14-16h)


title: Exemestane_Dose4_Rep1


title: Nelarabine_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad007

source_name: C57BL/6J Male P56 Mouse Brain


title: nFne_pooled_14-16h_9b_exp2

description:
nfne_wt.early.apa_targets.gene.tsv
Segments_split.early.gff


title: nFne_pooled_14-16h_9c_exp2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad010


title: nFne_pooled_14-16h_9a_exp2


title: elav-nFne_pooled_14-16h_10e_exp2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad006


title: Cimetidine_Dose4_Rep1

source_name: Pool of 5 breast cancer cell lines


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad002


title: elav-nFne_pooled_14-16h_10c_exp2


title: 29398: ICRH80


title: wt_pooled_14-16h_8b_exp2

description:
nfne_wt.early.apa_targets.gene.tsv
elav-nfne_wt.early.apa_targets.gene.tsv
Segments_split.early.gff


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G8_ad008


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G6_ad008


title: RITA_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G7_ad008


title: wt_pooled_18-22h_8c_exp2


title: 29387: ICRH80


title: Cediranib_Dose4_Rep1


title: PHA793887_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G6_ad006


title: Thalidomide_Dose4_Rep1


title: Mitoxantrone_Dose4_Rep1


title: wt_pooled_14-16h_8e_exp2


title: Temozolomide_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G5_ad012


title: Dexamethasone_Dose4_Rep1


title: wt_pooled_14-16h_8c_exp2


title: Regorafenib_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G5_ad007


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G6_ad007


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G5_ad006


title: Tacrolimus_Dose4_Rep1


title: Bendamustine_Dose4_Rep1


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G5_ad002


title: BrefeldinA_Dose3_Rep2


title: Brivanib_Dose3_Rep2


title: CEMBA190205_5A_1_CEMBA190205_5A_2_G5_ad008