title: RegJQ1_2

city: West Lafayette

first: Emily

last: Dykhuizen

state: IN

address: 201 S. University

department: medicinal chemistry and molecular pharmacology

institute: Purdue University

data_processing:
Data quality control and filtering was performed with Trim Galore.
Read-mapping against the human (hg19) genome was performed with STAR.
Raw read counts for each gene from each replicate were determined using HTSeq.
Differential expression analysis was performed with R-package edgeR .
Genome_build: hg19
Supplementary_files_format_and_content: xls files containing differentially expressed genes and counts

source_name: LNCaP cells

growth_protocol: LNCaP prostate cancer cell lines were grown under normal conditions: RPMI with 10% FBS

extract_protocol:
RNA was isolated from cells using Trizol® and following manufacturer's recommendations. RNA was further purified using Qiagen Rneasy kit.
Libraries were constructed using Ovation® Ultralow V2 DNA-Seq Library Preparation Kit from Tecan, according the manufacturer's instructions

treatment_protocol: knockdowns were generated using lentiviral mediated shRNA

tag: cell type

value: LNCaP

tag: treatment

value: CSS media for 24h and 500 nM JQ1 for 6h, then reg media and 500 nM JQ1 for 18h


title: RegJQ1_3

status: Public on Dec 28 2020

type: SRA

country: USA

library_source: transcriptomic

molecule: total RNA

organism: Homo sapiens


title: Subject ID: IN.ETU.035_IgA

type: protein

city: Irvine

first: Joseph

middle: John

last: Campo

state: CA

address: 1 Technology Dr., STE E309

institute: Antigen Discovery, Inc.

hyb_protocol: Milk samples were diluted 1:5 in a 1.5 mg/mL E. coli lysate solution (Antigen Discovery, Inc., Irvine, CA) in protein arraying buffer (GVS, Cat. 10485356, Sanford, ME) and incubated at room temperature for 30 min. For milk samples previously diluted in preservative solution, samples were diluted 1:2.5 in the lysate solution. Microarray slides were hydrated in arraying buffer and then probed with 250 µL of the preincubated milk samples using sealed, fitted slide chambers to avoid cross-contamination between arrays. Arrays were incubated overnight at 4°C with agitation, washed three times with Tris-buffered saline (TBS)-0.05% Tween 20 (Thermo Scientific, J77500K8, diluted 20x in molecular grade water), and incubated with Cy3-conjugated anti-human IgG diluted 1:200 in arraying buffer and biotin-conjugated anti-Human IgA diluted 1:1000 (Jackson ImmunoResearch, Cat. 709-165-098 and Cat. 109-065-011, West Grove, PA). Arrays were washed three times with TBS–0.05% Tween 20 and incubated with streptavidin-conjugated SureLight P-3 (Columbia Biosciences, Cat. D7-2212, Frederick, MD) at room temperature, protected from light. Arrays were washed 3x with TBS–0.05% Tween 20, 3x with TBS, and once with water and then air dried by being centrifuged at 1,000 x g for 4 min and left overnight in a desiccator before scanning.

scan_protocol: Probed microarrays were scanned using a GenePix 4300A high-resolution microarray scanner (Molecular Devices, Sunnyvale, CA), and an image file (.tiff) was saved for each array using GenePix pro 7 software. The signals in the scanned images were quantified using Mapix software (Innopsys).

data_processing: All further data processing was performed in R (http://www.R-project.org). Data were normalized by first transforming raw values using the base 2 logarithm. Next, the data set was normalized to remove systematic effects by subtracting the median signal intensity of the IVTT control spots from the IVTT antigen spots for each sample. Since the IVTT control spots carry not only the chip, sample, and batch-level systematic effects, but also antibody background reactivity to the E. coli cell-free IVTT system, this procedure normalizes the data and provides a relative measure of the specific antibody binding versus the nonspecific antibody binding to the IVTT controls. With the normalized data, a value of 0.0 means that the intensity is no different than that of the IVTT controls, a value of 1.0 indicates a doubling (2-fold) with respect to IVTT control spots, a value of 2.0 indicates 4-fold, 3.0 indicates 8-fold, etc. The normalized signal intensity of the purified protein spots is represented as the base 2 logarithm of the raw signal intensities.

label: biotin-conjugated anti-Human IgA/streptavidin-conjugated SureLight P-3

molecule: protein

source_name: human breast milk

label_protocol: biotin-conjugated anti-Human IgA (Jackson ImmunoResearch, Cat. 109-065-011, West Grove, PA) / streptavidin-conjugated SureLight P-3 (Columbia Biosciences, Cat. D7-2212, Frederick, MD)

extract_protocol: Sampling protocol: In PE, SW, USC, and USW, milk was collected using an electric breast pump. In all other cohorts, milk was manually expressed. Except for those collected in ETR, samples were immediately placed on ice, aliquoted within 30 min, and frozen at −20°C. Milk collected in ETR was preserved in a 1:1 ratio with Milk Preservation Solution (Norgen Biotek, Cat. 44800, Thorold, Ontario) and frozen within 6 d. We have shown previously that this method can maintain bacterial DNA integrity in human milk held at 37°C for at least 2 wk (34). All samples were shipped on dry ice to the University of Idaho, where they were immediately frozen at −20°C.

tag: region

value: Ethiopia, urban

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: Vaginal

tag: bmi

tag: bmi code

value: OVERWEIGHT

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density

tag: molecule type

value: IgA


title: Sample_75

city: Hangzhou

first: Zi

last: Yin

address: YuHangTang Road N0.866

country: China

institute: Zhejiang University

data_processing:
Single-cell RNA sequence reads were evaluated by AfterQC. Bad reads were detected automatically and removed. Bases at 3' end of the read were further timmed by NGSQCToolkit if their PHRED quality score were less than.
The reads were mapped to the mouse genome(mm10) using bowtie2.
The mapped reads for genes were counted via featureCounts. Gene expression was represented by CPM (tags per million).
Genome_build: mm10
Supplementary_files_format_and_content: tab-delimited text files include count values for each sample

organism: Mus musculus

source_name: SCX-GFP transgenic hind limb_E10.5

extract_protocol:
Single-cell capture, RNA extraction and cDNA synthesis were performed following the methods described in the Fluidigm protocol(PN 100-9886)
The cDNA reaction products were quantified using the Qubit and were then diluted to a final concentration of 0.2 ng/ μl using C1 Harvest Reagent. The diluted cDNA reaction products were then converted into mRNA-seq libraries using the Nextera XT DNA Sample Preparation Kit (Illumina, FC-131-1096, -2001 and -2002) following the manufacturer’s instructions.

treatment_protocol: Single-cell experiments were performed on the embryonic SCX-GFP C57BL/6 Transgenic Mouse  hindlimb at E10.5, E12.5 and E15.5. In general, embryonic experiments were performed on pooled sibling limbs of one litter (three to five limbs per pool). For each time point, embryos were dissected and limbs were isolated. We  finely chopped the tissue with small scissors in a drop of DMEM, and then digested the tissues in type I Collagenase 0.1% / Trypsin 0.05% (Life Technologies) diluted in low-glucose Dulbecco’s modified Eagle’s (L-DMEM) medium (Gibco) solution at 37°C for 10 min. Then, we let tissues to settle down and collected the supernatant in a fresh 50 ml tube, before adding 10-20% of fetal bovine serum to quench trypsin (on ice to stop collagenase). We repeated digestion steps for twice or more till all tissues are digested. The supernatants were then pooled. We filtered the pooled supernatants through 40µ cell filters (Falcon BD), and centrifuge for 10 min at 1600 rpm, before re-suspending the pellet in DMEM containing 2% serum, and kept cell suspension on ice until load on chip.

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: developmental stage

tag: tissue

value: hind limb


title: Subject ID: IN.ETU.034_IgA

tag: region

value: NORMAL


title: Sample_73


title: RegJQ1_1

tag: cell type

tag: treatment


title: RegIBRD3

value: CSS media for 24h and 3 uM IBRD9 for 6h, then reg media and 3 uM IBRD9 for 18h


title: Sample_72


title: Subject ID: IN.ETU.033_IgA

tag: mother's age

tag: infant's sex

tag: time post-partum

value: YES


title: RegIBRD2


title: genomic DNA from healthy adult distal femur trabecular bone Panu34_B (baboon_oa)

type: genomic

city: Chicago

first: Genevieve

last: Housman

state: IL

address: 920 East 58th Street, CLSC 317

department: Genetic Medicine

institute: University of Chicago

description: medial condyle healthy adult distal femur trabecular bone from baboon

hyb_protocol: Infinium MethylationEPIC array

scan_protocol: standard illumina scanner

data_processing:
Raw fluorescent data were normalized using the Noob background correction    method with dye-bias normalization followed with a between-array    normalization method (functional normalization) as implemented in the R    package minfi. After normalization, methylation values (beta values) for    each site were calculated as the ratio of methylated probe signal intensity    to the sum of both methylated and unmethylated probe signal intensities.
Those probes with failed detection levels (p-value > 0.05) in greater than    10% of samples were removed. Cross-reactive probes, probes containing SNPs    at the CpG site, probes detecting SNP information, probes detecting    methylation at non-CpG sites, and probes targeting sites within the sex    chromosomes were also removed using the minfi package in R.
Lastly, probes that were determined to be non-specific to each nonhuman    primate genome were also removed. Filtering for these files was based    on Hernando-Herraez  et al. (2013). Briefly, all 485,512 probes were mapped to the appropriate    nonhuman primate genome, and only those probes that successfully mapped to    the genome, had only 1 unique hit, and targeted CpG sites were retained.    Additionally, probes were kept for subsequent analyses only if they had 0    mismatches in 5bp closest to and including the CpG site, and had 0-2    mismatches in 45bp not including the CpG site.
- Hernando-Herraez I, Prado-Martinez J, Garg P, Fernandez-Callejo M,       Heyn H, Hvilsom C, et al. Dynamics of DNA methylation in recent human and       great ape evolution. PLOS Genet 2013;9:e1003763.
Nonhuman Primate Genome: Papio anubis

label: Cy5 and Cy3

molecule: genomic DNA

organism: Papio sp.

label_protocol: 400ng of DNA was bisulphite converted using the EZ DNA methylation kit (Zymo Research)

extract_protocol: genomic DNA was extracted from pulverized trabecular bone or homogenized cartilage using a phenol-cholorform protocol

tag: Sex

value: female

tag: age (years)

tag: steady state weight (kg)

value: bone

tag: age cohort

value: adult

tag: disease state

value: healthy


title: genomic DNA from healthy adult distal femur trabecular bone Panu13_B (baboon_oa)

source_name: healthy adult distal femur trabecular bone from baboon

value: male


title: Sample_78


title: RegIBRD1

value: LNCaP


title: genomic DNA from healthy adult distal femur trabecular bone Panu37_B (baboon_oa)


title: genomic DNA from healthy adult distal femur trabecular bone Panu47_B (baboon_oa)


title: Subject ID: IN.ETU.032_IgA

tag: parity

tag: delivery

tag: bmi

tag: bmi code

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density


title: genomic DNA from healthy adult distal femur trabecular bone Panu10_B (baboon_oa)

tag: tissue


title: genomic DNA from healthy adult distal femur trabecular bone Panu44_B (baboon_oa)


title: Sample_71

tag: strain background

tag: genotype/variation

tag: developmental stage


title: Sample_70


title: genomic DNA from healthy adult distal femur trabecular bone Panu48_B (baboon_oa)

tag: Sex


title: Subject ID: IN.ETU.031_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: molecule type


title: Sample_74


title: RegEnza3

tag: cell type

tag: treatment

value: CSS media for 24h and 10 uM ENZA for 6h, then reg media and 10 uM ENZA for 18h


title: Sample_69


title: Subject ID: IN.ETU.030_IgA

value: Ethiopia, urban

tag: parity

tag: delivery

tag: bmi

tag: bmi code


title: genomic DNA from healthy adult distal femur trabecular bone Panu03_B (baboon_oa)

tag: age (years)

tag: steady state weight (kg)

tag: age cohort

tag: disease state


title: Sample_68

tag: strain background

tag: genotype/variation

tag: developmental stage

tag: tissue


title: RegEnza2


title: genomic DNA from healthy adult distal femur trabecular bone Panu43_B (baboon_oa)

tag: Sex


title: Subject ID: IN.ETU.028_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

value: Vaginal

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density


title: Subject ID: IN.ETU.025_IgA

tag: parity

tag: delivery

tag: bmi

tag: bmi code

tag: molecule type


title: genomic DNA from healthy adult distal femur trabecular bone Panu56_B (baboon_oa)

tag: age (years)

tag: steady state weight (kg)

tag: age cohort

tag: disease state


title: Sample_67

tag: strain background

tag: genotype/variation

tag: developmental stage

tag: tissue


title: genomic DNA from healthy adult distal femur trabecular bone Panu46_B (baboon_oa)

tag: Sex


title: Sample_66


title: RegDMSO3

tag: cell type

tag: treatment

value: CSS media for 24h and DMSO for 6h, then reg media and DMSO for 18h


title: Sample_65


title: RegDMSO2


title: Subject ID: IN.ETU.023_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density


title: Sample_64


title: RegdBRD3

value: CSS media for 24h and 500 nM dBRD9 for 6h, then reg media and 500 nM dBRD9 for 18h


title: Subject ID: IN.ETU.022_IgA

tag: parity

tag: delivery

tag: bmi

tag: bmi code

value: OVERWEIGHT

tag: molecule type

value: IgA


title: Sample_63

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: developmental stage

tag: tissue

value: hind limb


title: RegdBRD2

tag: cell type

tag: treatment


title: RegEnza1


title: Subject ID: IN.ETU.021_IgA

tag: region

tag: mother's age

tag: infant's sex

value: UNDERWEIGHT


title: Sample_62


title: genomic DNA from healthy adult distal femur trabecular bone Panu42_B (baboon_oa)

tag: Sex

tag: age (years)

tag: steady state weight (kg)

tag: age cohort

tag: disease state


title: genomic DNA from healthy adult distal femur trabecular bone Panu21_B (baboon_oa)

value: female


title: RegDMSO1


title: Subject ID: IN.ETU.020_IgA

tag: time post-partum

tag: parity

tag: delivery

tag: bmi

value: NORMAL

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density


title: Subject ID: IN.ETU.019_IgA

tag: bmi code

value: YES

tag: molecule type


title: Subject ID: IN.ETU.024_IgA

tag: region

tag: mother's age


title: genomic DNA from healthy adult distal femur trabecular bone Panu45_B (baboon_oa)

tag: Sex

tag: tissue

value: bone

value: adult

value: healthy


title: Sample_61

tag: strain background

tag: genotype/variation

tag: developmental stage


title: IBRD9_3

tag: cell type

value: LNCaP

tag: treatment

value: 5 uM IBRD9 for 3d


title: Subject ID: IN.ETU.018_IgA

value: Ethiopia, urban

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: Vaginal


title: Sample_60


title: Input MEF DNA

city: Suwon

first: Hyun-Soo

last: Kim

address: 2066, SEOBU-RO, JANGAN-GU, SUWON-SI, GYEONGGI-DO

department: School of medicine

country: South Korea

institute: SUNGKYUNKWAN UNIVERSITY

library_source: genomic

data_processing:
MACS 1.4.2 used for basecalling.
Raw reads were mapped to UCSC mouse genome browser (GRCm38/mm10 assembly) using ELAND algorithm integrated within Illumina sequencing analysis software.
All duplicate tags with identical sequences and possible sequencing artifacts were filtered out with PICRAD 1.76 pipeline.
Genome ChIP-seq data were generated using MACS 1.4.2 with unique mapped reads. Read counts of all ChIP-Seq peaks were normalized through comparison between library-size-normalized input and ChIP samples.
Genome_build: mm10
Supplementary_files_format_and_content: Each sample was generated by bigwig files

source_name: Embryonic fibroblast

extract_protocol:
Lysates were clarified from sonicated nuclei and protein-chromatin complexes were isolated with antibody.
Libraries were prepared according to Illumina's instructions accompanying the DNA Sample Kit and sequenced on the Genome Analyzer following the manufacturer's protocols.

tag: strain

value: Embryonic fibroblast

value: Embryonic day 13.5

tag: virus infection

value: Luciferase adenovirus infection

tag: genotype

value: WT

tag: chip antibody

value: none (input)


title: RegdBRD1

value: CSS media for 24h and 500 nM dBRD9 for 6h, then reg media and 500 nM dBRD9 for 18h


title: Ssu72 KO MEF Pol II pThr4 ChIP

value: Cre recombinase adenovirus infection

value: Ssu72 KO

value: phospho CTD Thr4 (Active Motif, 6D7, 61307)


title: genomic DNA from healthy adult distal femur trabecular bone Panu19_B (baboon_oa)

value: female

tag: age (years)

tag: steady state weight (kg)

tag: age cohort

tag: disease state


title: Subject ID: IN.ETU.017_IgA

tag: region

tag: mother's age

tag: bmi

tag: bmi code

value: NORMAL

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density

tag: molecule type

value: IgA


title: genomic DNA from healthy adult distal femur trabecular bone Panu53_B (baboon_oa)

tag: Sex

tag: tissue

value: bone

value: adult

value: healthy


title: genomic DNA from healthy adult distal femur trabecular bone Panu33_B (baboon_oa)


title: Ssu72 KO MEF Pol II pSer7 ChIP

tag: strain

tag: cell type

tag: developmental stage

tag: virus infection

tag: genotype

value: phospho CTD Ser7 (Millipore, 4E12, 04-1570)


title: IBRD9_1

value: LNCaP

tag: treatment

value: 5 uM IBRD9 for 3d


title: genomic DNA from healthy adult distal femur trabecular bone Panu08_B (baboon_oa)

value: male

tag: age (years)

tag: steady state weight (kg)

tag: age cohort

tag: disease state


title: Sample_58

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

value: hind limb


title: Sample_57


title: DMSO2

value: DMSO for 3d


title: DMSO3


title: genomic DNA from healthy adult distal femur trabecular bone Panu41_B (baboon_oa)


title: Sample_56


title: Subject ID: IN.ETU.016_IgA

tag: region

value: Ethiopia, urban

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: Vaginal

tag: bmi

tag: bmi code

value: OVERWEIGHT

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals


title: Ssu72 KO MEF Pol II ChIP

tag: strain

tag: cell type

value: Embryonic fibroblast

tag: developmental stage

value: Embryonic day 13.5

tag: virus infection

value: Cre recombinase adenovirus infection

tag: genotype

value: Ssu72 KO

tag: chip antibody

value: Rpb1 (Santa Cruz Biotechnology, sc-899)


title: genomic DNA from healthy adult distal femur trabecular bone Panu39_B (baboon_oa)

tag: Sex

value: female

tag: age (years)

tag: steady state weight (kg)

tag: tissue

value: bone

tag: age cohort

value: adult

tag: disease state


title: DMSO1

value: LNCaP

tag: treatment


title: Subject ID: IN.ETU.015_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

tag: bmi

tag: bmi code

value: NORMAL

value: NO

value: YES

tag: adjusted household density

tag: molecule type

value: IgA


title: Sample_59

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: developmental stage

value: hind limb


title: Subject ID: IN.ETU.014_IgA

value: Ethiopia, urban

value: Vaginal

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals


title: Ssu72 KO MEF Pol II pSer2 ChIP

tag: strain

tag: cell type

value: Embryonic fibroblast

tag: virus infection

tag: genotype

tag: chip antibody

value: phospho CTD Ser2 (Millipore, 3E10, 04-1571)


title: Subject ID: IN.ETU.013_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity


title: IBRD9_2

tag: treatment

value: 5 uM IBRD9 for 3d


title: csJQ1_3

value: CSS media for 24h and JQ1 for an additional 24h


title: Ssu72 WT MEF Pol II pThr4 ChIP

value: Embryonic day 13.5

value: Luciferase adenovirus infection

value: WT

value: phospho CTD Thr4 (Active Motif, 6D7, 61307)


title: genomic DNA from healthy adult distal femur trabecular bone Panu55_B (baboon_oa)

tag: Sex

value: male

tag: age (years)

tag: steady state weight (kg)

tag: tissue

value: bone

tag: age cohort

value: adult

tag: disease state

value: healthy


title: Subject ID: IN.ETU.012_IgA

tag: delivery

tag: bmi

tag: bmi code

value: NORMAL

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density

tag: molecule type

value: IgA


title: Sample_53

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: developmental stage

value: hind limb


title: csJQ1_2

tag: cell type

value: LNCaP

tag: treatment


title: Sample_54


title: Ssu72 WT MEF Pol II pSer7 ChIP

tag: strain

value: Embryonic fibroblast

tag: virus infection

tag: genotype

tag: chip antibody

value: phospho CTD Ser7 (Millipore, 4E12, 04-1570)


title: Sample_52

tag: tissue


title: Ssu72 WT MEF Pol II pSer2 ChIP

value: phospho CTD Ser2 (Millipore, 3E10, 04-1571)


title: Subject ID: IN.ETU.011_IgA

tag: region

value: Ethiopia, urban

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: Vaginal

tag: bmi


title: Ssu72 WT MEF Pol II pSer5 ChIP

value: Embryonic day 13.5

value: Luciferase adenovirus infection

value: WT

value: phospho CTD Ser5 (Millipore, 3E8, 04-1572)


title: csJQ1_1

value: CSS media for 24h and JQ1 for an additional 24h


title: csIBRD3

value: CSS media for 24h and 3 uM IBRD9 for an additional 24h


title: Subject ID: IN.ETU.010_IgA

tag: bmi code

value: OVERWEIGHT

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

value: YES

tag: adjusted household density

tag: molecule type


title: Ssu72 WT MEF Pol II ChIP

tag: strain

tag: cell type

tag: developmental stage

tag: virus infection

value: Rpb1 (Santa Cruz Biotechnology, sc-899)


title: csIBRD2

tag: treatment


title: csIBRD1


title: Sample_55

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: tissue


title: Subject ID: IN.ETU.009_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

value: NORMAL

value: NO

value: IgA


title: Subject ID: IN.ETU.008_IgA

tag: delivery

tag: bmi

tag: bmi code

tag: mother's height (cm)

tag: companion animals


title: Ssu72 KO MEF Ssu72 ChIP

description: Two biological replicates were included. Each is represented by an independent SRR id.

tag: strain

tag: cell type

value: Embryonic fibroblast

value: Cre recombinase adenovirus infection

tag: genotype

value: Ssu72 KO

tag: chip antibody

value: Ssu72 (Cell Signaling, #12816)


title: csEnza3

value: LNCaP

tag: treatment

value: CSS media for 24h and 10 uM ENZA for an additional 24h


title: Subject ID: IN.ETU.007_IgA

value: Ethiopia, urban

value: Vaginal

tag: agricultural animals

tag: adjusted household density

tag: molecule type


title: Sample_50

tag: strain background

tag: genotype/variation

tag: developmental stage

tag: tissue

value: hind limb


title: Subject ID: IN.ETU.006_IgA

tag: region

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery


title: Ssu72 WT MEF Ssu72 ChIP

tag: strain

tag: cell type

value: Embryonic day 13.5

tag: virus infection

value: Luciferase adenovirus infection

value: WT


title: Sample_48


title: Sample_49


title: csEnza2

tag: treatment


title: Ssu72 WT ES cell  Ssu72 ChIP

source_name: Embryonic stem cells

value: Embryonic stem cells

value: inner cell mass

tag: genotype

tag: chip antibody


title: Sample_51

value: SCX-GFP transgenic


title: Sample_47


title: Subject ID: IN.ETU.002_IgA

tag: bmi

tag: bmi code

value: NORMAL

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density

tag: molecule type


title: Sample_46

tag: strain background

tag: genotype/variation

tag: developmental stage

tag: tissue


title: csEnza1


title: Ssu72 KO hepatocyte 3

data_processing:
Illumina Casava software used for basecalling.
RNA-Seq reads were then mapped to mouse mm10 reference genome using Tophat (v2.0.13), allowing a maximum of two mismatches per 75 bp sequencing end. Differential gene expression analysis was performed using packages DESeq and edgeR. Raw read counts were used and modeled based on negative binomial distribution.
Fragments Per Kilobase Million (FPKM) were calculated using cuffdiff v2.2.0
Genome_build: mm10
Supplementary_files_format_and_content: Text files include FPKM values for each sample.

source_name: hepatocyte

extract_protocol:
Each RNA was harvested using Trizol reagent. Each sample was prepared with 1 ug of total RNA for the construction of sequencing libraries.
RNA libraries were prepared for sequencing using standard Illumina protocols

tag: strain

value: hepatocyte

value: Purified hepatocytes of 6weeks mice

tag: condition


title: Ssu72 KO hepatocyte 2

tag: cell type

value: Cre recombinase adenovirus infection

value: Ssu72 KO


title: Sample_45


title: csDMSO3

value: LNCaP

tag: treatment

value: CSS media for 24h and DMSO for an additional 24h


title: Ssu72 WT hepatocyte 3

tag: genotype


title: Ssu72 KO hepatocyte 1


title: Sample_43


title: csdBRD3

value: CSS media for 24h and 500 nM dBRD9 for an additional 24h


title: csDMSO2


title: Sample_44


title: Subject ID: IN.ETR.142_IgA

tag: region

value: Ethiopia, rural

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: Vaginal

value: UNDERWEIGHT

value: YES

value: IgA


title: Sample_42

value: hind limb


title: Ssu72 WT hepatocyte 2

value: Luciferase adenovirus infection

value: WT


title: Subject ID: IN.ETR.141_IgA

tag: bmi

tag: bmi code

value: OVERWEIGHT

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density


title: Subject ID: IN.ETR.140_IgA

value: NO

tag: molecule type


title: csdBRD2


title: csDMSO1


title: Sample_41

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: developmental stage

tag: tissue


title: Subject ID: IN.ETR.139_IgA

tag: region


title: Subject ID: IN.ETU.004_IgA

value: Ethiopia, urban

tag: mother's age

value: NORMAL


title: Subject ID: IN.ETR.138_IgA

tag: infant's sex


title: Ssu72 KO MEF 3

tag: strain

tag: cell type

value: Embryonic fibroblast

value: Embryonic day 13.5

tag: condition

value: Cre recombinase adenovirus infection

tag: genotype

value: Ssu72 KO


title: Sample_40


title: Subject ID: IN.ETU.001_IgA

tag: time post-partum

tag: parity

tag: delivery

tag: bmi

tag: bmi code


title: Ssu72 KO MEF 2


title: shBRD93-3d

value: LNCaP

tag: genetic manipulation

value: lentivirus with inducible shBRD9

tag: treatment

value: 3d doxycycline


title: Sample_39

tag: strain background

tag: genotype/variation


title: Ssu72 KO MEF Pol II pSer5 ChIP

tag: developmental stage

tag: virus infection

tag: chip antibody

value: phospho CTD Ser5 (Millipore, 3E8, 04-1572)


title: Subject ID: IN.ETR.137_IgA

tag: region

value: Ethiopia, rural

tag: mother's age

tag: infant's sex

value: Vaginal

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

value: YES

tag: adjusted household density

tag: molecule type

value: IgA


title: shBRD92-3d

tag: cell type


title: Ssu72 WT hepatocyte 1

tag: strain

value: hepatocyte

value: Purified hepatocytes of 6weeks mice

tag: condition

value: Luciferase adenovirus infection

tag: genotype

value: WT


title: Ssu72 KO MEF 1


title: Ssu72 WT MEF 3


title: shBRD91-3d

tag: genetic manipulation

tag: treatment


title: shScr3-3d

value: lentivirus with inducible shScrambled


title: Sample_37

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

tag: developmental stage

tag: tissue

value: hind limb


title: Sample_38


title: Ssu72 WT MEF 2

value: Embryonic fibroblast

value: Embryonic day 13.5


title: Sample_36


title: Subject ID: IN.ETR.135_IgA

tag: region

tag: mother's age

tag: time post-partum

tag: parity

tag: delivery

tag: bmi

tag: bmi code

value: OVERWEIGHT

value: NO


title: Ssu72 WT MEF 1

tag: cell type


title: Subject ID: IN.ETR.134_IgA

tag: infant's sex

value: NORMAL

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density

tag: molecule type


title: csdBRD1

value: LNCaP

tag: treatment

value: CSS media for 24h and 500 nM dBRD9 for an additional 24h


title: Sample_35

tag: strain background

tag: genotype/variation

tag: developmental stage


title: Subject ID: IN.ETR.133_IgA

tag: region

value: Ethiopia, rural

tag: mother's age

value: Vaginal

value: UNDERWEIGHT


title: shScr2-3d

tag: genetic manipulation

value: 3d doxycycline


title: Ssu72 KO ES cell 2

tag: strain

value: Embryonic stem cells

value: inner cell mass

tag: condition

value: Cre recombinase adenovirus infection

tag: genotype

value: Ssu72 KO


title: shScr1-3d

tag: cell type

value: lentivirus with inducible shScrambled


title: Sample_34

value: SCX-GFP transgenic

tag: tissue

value: hind limb


title: Ssu72 KO ES cell 1


title: Subject ID: IN.ETR.132_IgA

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

tag: bmi

tag: bmi code

tag: mother's height (cm)

value: YES

value: IgA


title: Sample_33

tag: strain background

tag: genotype/variation


title: Subject ID: IN.ETR.131_IgA

tag: region

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density

tag: molecule type


title: Subject ID: IN.ETR.136_IgA

tag: mother's age

value: NORMAL


title: Ssu72 WT ES cell 2

tag: strain

tag: cell type

tag: developmental stage

tag: condition

value: Luciferase adenovirus infection

tag: genotype

value: WT


title: Ssu72 WT ES cell 1


title: Subject ID: IN.ETR.129_IgA

value: Ethiopia, rural

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: OVERWEIGHT


title: Sample_30

tag: strain background

tag: tissue


title: Subject ID: IN.ETR.127_IgA

tag: region

value: Vaginal

tag: bmi

tag: bmi code

tag: mother's height (cm)


title: Sample_28

tag: genotype/variation


title: Subject ID: IN.ETR.128_IgA

tag: mother's age

tag: companion animals

tag: agricultural animals

tag: adjusted household density

tag: molecule type


title: Subject ID: IN.ETR.125_IgA


title: Subject ID: IN.ETR.124_IgA


title: Subject ID: IN.ETR.123_IgA


title: Sample_25

tag: developmental stage


title: Subject ID: IN.ETR.121_IgA

tag: infant's sex


title: Subject ID: IN.ETR.119_IgA

tag: time post-partum


title: B. subtilis_GP2223_NH4_5mM K_rep1

type: RNA

city: Greifswald

first: Ulrike

last: Mäder

address: F.-L.-Jahn-Str. 15A

department: Functional Genomics

country: Germany

institute: University Medicine Greifswald

hyb_protocol: 200 ng of Cy3-labeled cDNA were hybridized to the tiling array following Agilent’s hybridization, washing and scanning protocol (One-Color Microarray-based Gene Expression Analysis, version 5.5).

scan_protocol: The microarray was scanned using an Agilent Microarray Scanner G2505C (Agilent Technologies).

data_processing:
Data were extracted using the Agilent Feature Extraction software (version 11.5.1.1, Agilent Technologies). Probe intensities were computed from the raw intensity data using a model of signal shift and drift and correcting for probe affinity variations as described before (Nicolas
et al., 2009; PMID 19561016). An aggregated expression value was computed for each annotated CDS and previously identified RNA feature (Nicolas et al., 2012; PMID 22383849) as the median log2 intensity of probes lying entirely within the corresponding region.
Gene-level intensities were scaled based on the intensity values of ten different in-vitro synthesized transcripts contained in the One Color RNA Spike-In kit (Agilent Technologies).

organism: Bacillus subtilis subsp. subtilis str. 168

source_name: B. subtilis GP2223_NH4_5mM K_OD0.4-0.6

label_protocol:
For cDNA synthesis, 5 µg of total RNA were mixed with random primers (FairPlay III Microarray Labeling Kit) and spike-ins (One-Color RNA Spike-In Kit, Agilent Technologies) and incubated at 70°C for 10 min followed by 5 min incubation on ice. Then, first-strand Master Mix,
Actinomycin D (final conc. 40 µg/ml) and AffinityScript HC Reverse Transcriptase were added. The reaction was incubated for 60 min at room temperature and for 60 min at 42°C. After hydrolyzing the RNA, cDNA was precipitated overnight at -20°C. NHS-ester dye coupling
(CyDye Mono-Reactive Dye, GE Healthcare) and purification of labeled cDNA were performed according to the FairPlay III instructions. cDNA and Cy-dye concentrations were quantified by means of a NanoDrop spectrophotometer.

growth_protocol: B. subtilis was grown aerobically at 37 °C in MSSM medium with ammonium or glutamate and low (0.1 mM) or high (5 mM) potassium concentrations. Cells were harvested at mid exponential phase (OD at 600 nm of 0.4-0.6).

extract_protocol: Cells were harvested and total RNA was isolated by the mechanical cell disruption/ acid phenol method (Eymann et al., 2002; PMID 11948165).

tag: growth

value: NH4 + 5mM K

tag: genotype/strain

value: B. subtilis GP2223 ({delta}disA, {delta}cdaA, {delta}cdaS, nhaKS187F)


title: Subject ID: IN.ETR.130_IgA

tag: parity

tag: delivery


title: Sample_31

tag: strain background

tag: tissue


title: Sample_26


title: B. subtilis_GP2222_NH4_0.1mM K_rep2

value: NH4 + 0.1mM K

value: B. subtilis GP2222 ({delta}disA, {delta}cdaA, {delta}cdaS)


title: Subject ID: IN.ETR.122_IgA

tag: region

tag: bmi

tag: bmi code


title: U937_prexasertib_LSN622666_3

city: Rochester

first: Hu

last: Li

state: MN

address: 200 First Street, Gonda Building G19-408

department: Molecular Pharmacology & Experimental Therapeutics

institute: Mayo Clinic

description: U937 treated with 10nM prexasertib plus 350nM LSN622666 for 24 hours,sample 3

data_processing:
Fastq files of pair-end RNA-Seq reads were aligned with Tophat 2.0.14  to the reference genome UCSC hg38 using Bowtie2 2.2.6 with default parameters.
Gene level counts were obtained using featureCounts 1.4.6 from the subRead package with gene models from corresponding UCSC annotation packages.
Genome_build: hg38
Supplementary_files_format_and_content: raw counts in tab-delimited text file

source_name: Tissue culture cell line U937

growth_protocol: ML1 and U937 cells were grown in RPMI with 10% FBS under 5% CO2 at 37°C

extract_protocol:
RNA was column-extracted using Rneasy Mini kit (qiagen)
RNA-seq libraries were prepared from 100-200 ng high-quality RNA using TruSeq RNA Library Prep Kit v2 (Illumina)

treatment_protocol: ML1 and U937 cells were treated for 24 hours with diluent or 10 nM prexasertib in the absence or presence of 350 nM LSN622666 in the presence of  in 5 μM Q-VD-OPh .

tag: cell line

value: Acute Myeloid Leukemia (blood)

tag: agent

value: 10nM prexasertib plus 350nM LSN622666


title: Sample_22

tag: genotype/variation

value: SCX-GFP transgenic


title: B. subtilis_GP2222_NH4_0.1mM K_rep1


title: B. subtilis_GP2223_NH4_5mM K_rep2


title: Sample_29

value: hind limb


title: Sample_23


title: Subject ID: IN.ETR.118_IgA

tag: mother's age

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

value: YES

tag: adjusted household density


title: Sample_27

tag: developmental stage


title: B. subtilis_168_Glu_5mM K_rep2

source_name: B. subtilis 168_Glu_5mM K_OD0.4-0.6

tag: growth

value: Glu + 5mM K

tag: genotype/strain

value: Bacillus subtilis 168 (trpC2)


title: U937_prexasertib_LSN622666_2

description: U937 treated with 10nM prexasertib plus 350nM LSN622666 for 24 hours,sample 2


title: B. subtilis_168_Glu_0.1mM K_rep2

source_name: B. subtilis 168_Glu_0.1mM K_OD0.4-0.6

value: Glu + 0.1mM K


title: B. subtilis_168_Glu_5mM K_rep1


title: B. subtilis_168_Glu_0.1mM K_rep1


title: Subject ID: IN.ETR.117_IgA

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: NORMAL

value: NO

tag: molecule type

value: IgA


title: B. subtilis_168_NH4_5mM K_rep2

source_name: B. subtilis 168_NH4_5mM K_OD0.4-0.6


title: Sample_21

tag: strain background

tag: tissue


title: U937_prexasertib_LSN622666_1

description: U937 treated with 10nM prexasertib plus 350nM LSN622666 for 24 hours,sample 1

tag: cell line

tag: agent


title: Subject ID: IN.ETR.115_IgA

tag: region

value: Ethiopia, rural

tag: mother's age

tag: bmi

tag: bmi code

value: UNDERWEIGHT


title: U937_prexasertib_3

description: U937 treated with 10nM prexasertib for 24 hours,sample 3

value: 10nM prexasertib


title: Sample_19

tag: genotype/variation


title: Subject ID: IN.ETR.114_IgA

value: Vaginal

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density


title: NOD_mouse_ileum_TP41

city: Piscataway

first: Xue-Song

last: Zhang

state: NJ

address: 679 Hoes Lane West, Room 113

department: CABM

institute: Rutgers University

description: cecal material transfer

hyb_protocol: Samples were hybridized for 18 h at 65C according to the instructions at nCounter® miRNA Expression Assay User Manual (NanoString tecnology)

scan_protocol: Scanned according to the manufacturer's protocol. Data Collection is carried out in the nCounterÎ Digital Analyzer. Digital images are processed on the nCounter Digital Analyzer and the barcode counts are tabulated in a comma separated value (CSV) format.

data_processing: Counts were normalized according to manufacturer’s instructions, Heat maps were generated using the pheatmap package in R

label: Nanostring

source_name: T1D project

label_protocol: total RNA was used for the miRNA Sample Preparation Protocol according to the instructions at nCounter® miRNA Expression Assay User Manual. Then prepared samples were labed with Reporter CodeSet and Capture ProbeSet from Mouse miRNA V 1.5 panel according to the instructions at nCounter® miRNA Expression Assay User Manual(NanoString tecnology)

extract_protocol: NOD mouse tissueThe total RNA was isolated from cells by using RNeasy Plus Mini Kit (Qiagen)

treatment_protocol: NOD/ShiLtJ mice dams and their litters were randomly assigned to control, antibiotic  and restoration (cecal microbiota transfer) groups.

tag: strain

value: NOD

tag: gender

value: male

tag: age

value: ileum

tag: batch


title: U937_prexasertib_2

description: U937 treated with 10nM prexasertib for 24 hours,sample 2

value: Acute Myeloid Leukemia (blood)


title: U937_prexasertib_1

description: U937 treated with 10nM prexasertib for 24 hours,sample 1


title: U937_diluent_3

description: U937 treated with diluent for 24 hours ,sample 3

value: diluent


title: B. subtilis_168_NH4_0.1mM K_rep2

tag: growth

value: NH4 + 0.1mM K

tag: genotype/strain


title: Subject ID: IN.ETR.113_IgA

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

value: YES

tag: molecule type


title: Sample_17

tag: strain background

value: SCX-GFP transgenic

tag: developmental stage

tag: tissue

value: hind limb


title: Sample_16

tag: genotype/variation


title: B. subtilis_168_NH4_0.1mM K_rep1

value: Bacillus subtilis 168 (trpC2)


title: U937_diluent_2

description: U937 treated with diluent for 24 hours ,sample 2

tag: cell line

tag: agent


title: Sample_20


title: NOD_mouse_ileum_TP39

description: cecal material transfer

tag: strain


title: U937_diluent_1

description: U937 treated with diluent for 24 hours ,sample 1


title: B. subtilis_168_NH4_5mM K_rep1

value: NH4 + 5mM K


title: Sample_15


title: NOD_mouse_ileum_TP38

description: cecal material transfer

tag: gender


title: NOD_mouse_ileum_TM51

description: 1PAT antibiotics

tag: age


title: Subject ID: IN.ETR.112_IgA

tag: region

tag: mother's age

tag: bmi

tag: bmi code

value: NORMAL

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

tag: adjusted household density


title: Subject ID: IN.ETR.111_IgA

value: Ethiopia, rural

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

tag: molecule type

value: IgA


title: Subject ID: IN.ETR.108_IgA


title: Subject ID: IN.ETR.107_IgA


title: Sample_14

tag: strain background

tag: genotype/variation

tag: developmental stage

tag: tissue


title: ML1_prexasertib_3

description: ML1 treated with 10nM prexasertib for 24 hours,sample 3

source_name: Tissue culture cell line ML1

tag: cell line

tag: agent

value: 10nM prexasertib


title: Sample_18


title: Sample_13


title: Subject ID: IN.ETR.106_IgA

tag: region

tag: mother's age

value: Vaginal

tag: bmi


title: NOD_mouse_ileum_TM49

description: 1PAT antibiotics

tag: strain

value: NOD

tag: gender

tag: age

tag: batch


title: Subject ID: IN.ETR.105_IgA

tag: infant's sex

tag: time post-partum

tag: bmi code

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals

tag: adjusted household density


title: ML1_prexasertib_2

description: ML1 treated with 10nM prexasertib for 24 hours,sample 2

tag: tissue


title: Sample_12

tag: strain background

tag: genotype/variation

tag: developmental stage


title: Subject ID: IN.ETR.104_IgA

tag: region

tag: mother's age

tag: parity

tag: delivery

tag: molecule type


title: ML1_prexasertib_1

description: ML1 treated with 10nM prexasertib for 24 hours,sample 1

tag: cell line

tag: agent


title: ML1_diluent_3

description: ML1 treated with diluent for 24 hours ,sample 3


title: Sample_10


title: NOD_mouse_ileum_TM47

description: 1PAT antibiotics

tag: strain

tag: gender

value: male

tag: age

tag: batch


title: ML1_diluent_2

description: ML1 treated with diluent for 24 hours ,sample 2


title: Sample_11


title: NOD_mouse_ileum_TP40

description: cecal material transfer

value: ileum


title: Sample_9


title: ML1_diluent_1

description: ML1 treated with diluent for 24 hours ,sample 1, 5uM QVD in all treatments below

value: Acute Myeloid Leukemia (blood)


title: NOD_mouse_ileum_CP39

description: control


title: NOD_mouse_ileum_CP37

description: control


title: Subject ID: IN.ETR.103_IgA

tag: infant's sex

tag: time post-partum

tag: bmi

tag: bmi code

tag: mother's height (cm)

tag: companion animals

tag: agricultural animals


title: NOD_mouse_ileum_CP38

description: control

tag: tissue


title: Subject ID: IN.ETR.101_IgA

tag: region

tag: mother's age

tag: parity

tag: adjusted household density


title: Sample_7

tag: strain background

tag: genotype/variation

tag: developmental stage


title: NOD_mouse_ileum_CP36

description: control

tag: strain

tag: gender

tag: age


title: RNA_Sac_sta

city: Kyoto

first: Naomichi

last: Takemata

address: Kyoto University, Katsura, Nishikyo-ku

department: Synthetic Chemistry and Biological Chemistry

country: Japan

institute: Kyoto University

data_processing:
3C-seq reads were mapped to the genome of S. acidocaldarius DSM639 (GenBank ID: CP000077.1) or S. islandicus REY15A (GenBank ID: CP002425.1) using HiC-Pro version 2.9.0 (Servant et al., 2015) with default parameters. The genomic coordinates of each Sulfolobus species were re-defined so that they started from the first base of the AluI site in the original definition. Valid read were used to generate raw contact matrices. The intra-bin ligations were discarded by setting the values on the corresponding diagonal to zero. The raw contact matrices were iteratively corrected with MAX_ITER = 500 (and FILTER_LOW_COUNT_PERC = 0.01 for S. islandicus) to generate normalized contact matrices.
To calculate Transcripts Per Million (TPM), RNA-seq reads from each biological replicate were mapped in a strand-specific manner using Salmon version 0.8.2 (Patro et al., 2017). When gene expression was quantified at the operon level, reads were mapped to operons predicted by Operon-mapper (Taboada et al., 2018).
Genome_build: CP000077.1, CP002425.1
Supplementary_files_format_and_content: 3C-seq: tab-delimited tables. The first and second columns show genomic bins. The third column shows interaction scores (raw number of reads or normalized value) between bins in the first and second columns. RNA-seq: tab-delimited tables showing Transcripts Per Million (TPM) values for each genes.

organism: Sulfolobus acidocaldarius

source_name: Microorganism

extract_protocol: To prepare the material for RNA-seq library construction, RNA was extracted as described previously (Takemata et al., 2019). After treatment with DNase, the RNA was ethanol-precipitated and dissolved in DEPC-treated water. Libraries were constructed using NEBNext Ultra II Directional RNA Library Prep Kit for Illumina.

tag: genotype

value: Wild type

value: Stationary-phase cells


title: 1 in 300,000 OPE mixture 24h rep3 [M3_24_3]

city: Montreal

first: Barbara

middle: F.

last: Hales

state: QC

address: 3655 Prom. Sir William Osler, room 110

department: Pharmacology and Therapeutics

country: Canada

institute: McGill University

data_processing:
Base calling was performed using Illumina CASAVA (v1.8)
Sequences were filtered for reads containing adapter or of low quality, then mapped to mm10 using STAR (v2.5, mismatch=2)
Quantification was performed using HTSeq (v0.6.1, -m union)
Differential analysis was performed using DESeq2 (v2_1.6.3, q-value < 0.05)
Genome_build: mm10
Supplementary_files_format_and_content: Matrix table containing raw count, FPKM value, and normalized abundance output (from DESeq2) of each gene for each sample and each treatment group

source_name: Embryonic forelimb

extract_protocol:
Cultured limb buds were preserved in RNAlater (Qiagen) and RNA was extracted using the Qiagen RNeasy Plus Mini Kit
mRNA was purified from 1ug of total RNA using poly-T oligo-attached magnetic beads and fragmented randomly in a fragmentation buffer. First-strand cDNA was synthesized using random hexamer primer and M-MuLV Reverse Transcriptase (RNase H-); second-strand cDNA was subsequently synthesized using DNA Polymerase I and RNase H. Double-stranded cDNA was purified using AMPure XP beads. Remaining overhangs were converted into blunt ends via exonuclease/polymerase activities. After adenylation of the 3' ends of DNA fragments, NEBNext Adaptor was ligated to prepare for hybridization. The library fragments were purified with AMPure XP system. The final library was obtained by PCR amplification and purification of PCR products using AMPure XP beads.

tag: gestation day

value: GD 13

value: limb bud

tag: treatment

value: 1 in 300,000 dilution of a house dust-based OPE mixture

tag: time point

value: 24 hours


title: RNA_Sac_log

value: Log-phase cells


title: Sample_8

value: SCX-GFP transgenic

value: hind limb


title: Sample_6


title: NOD_mouse_ileum_TM48

description: 1PAT antibiotics

tag: batch


title: RqcH-IP/total tRNA 3-1

city: Hamburg

first: Zoya

last: Ignatova

address: Martin -Luther-King-Platz 6

institute: Universitaet Hamburg

description: Biological replicate 3 of 3 Cy3 vs 1 of 1 Atto

hyb_protocol: 1. Fluorescently labeled tRNAs were hybridized on the microarrays for 16 h at 60°C in a Hyb4 microarray hybridization system (Digilab) supplemented with polyA (0.17 mg/ml) and salmon sperm DNA (0.17 mg/ml). 2. Microarrays were washed once in 2× SSC/0.1% SDS (50°C), once in 1× SSC/0.1% SDS (42°C) and then three times in 0.1× SSC (42°C). 3. Arrays were dried and stored in the dark at 4°C.

scan_protocol: Arrays were scanned with a GenPIX 4200A (Molecular Devices) instrument.

data_processing:
1. TIF-files of scanned arrays were analyzed using the GenePix Pro 7 (Molecular Devices) software.
2. Ratios of  Cy3/Atto635 fluorescence signals were calculated for individual spots based on median fluorescence signal (background fluorescence subtraction).
3. Cy3 532/Atto635 ratios were normalized to Cy3 532/Atto635 values of tRNA standards (e.g. median Cy3 532/Atto635 ratios of the four tRNA standards human tRNAGln1, human tRNAHis1, human tRNASer3) for individual blocks.
4. Normalized Cy3 532/Atto635 ratios for individual blocks were averaged, representing final Cy3 532/Atto635 ratios; detailed protocol for  narmalization using the dye control slide is published in: https://www.protocols.io/view/microarray-based-quantification-of-cellular-trnas-hfcb3iw or in : Dittmar KA, Mobley EM, Radek AJ, Pan T. (2004) Exploring the regulation of tRNA distribution on the genomic scale. J Mol Biol 12, 31-47

source_name: cultivated cells

label_protocol:
1. Equal amounts of in vitro synthesized tRNA standards (4 pmol each; human tRNAGln1, human tRNAHis1, human tRNASer3) were added to 2 µg extracted total RNA.
2. Cy3 or Atto653 containing oligonucleotides (Microsynth) were ligated to tRNA 3'-CCA ends using 20 U/μl T4 DNA ligase (New England Biolabs) for 1h at RT in the presence of 15% DMSO (Sigma-Aldrich).

growth_protocol:
Cells were pre-grown on LB plates overnight at 30 °C. Fresh individual colonies were used to inoculate 200 mL LB cultures. The cultures were grown until OD600 of 0.8 at 37 °C.
Cell were grown independently for each biological experiment.

extract_protocol: Total RNA for total tRNA arrays was extracted using TriReagent (Sigma-Aldrich)  according to manufacturer's protocol

tag: sample type

value: total lysate

tag: patient identifier

tag: cell line

value: RqcH IP


title: 3C_Sac_sta_rep2

extract_protocol: To prepare the material for 3C-seq library construction, cells were crosslinked, permeabilized, and treated with AluI. The DNA was then subjected to proximity ligation, crosslink reversal, and phenol extraction followed by isopropanol precipitation. Libraries were constructed using NEBNext Ultra DNA Library Prep Kit for Illumina.


title: Sample_5

tag: tissue


title: Subject ID: IN.ETR.102_IgA

tag: region

value: Ethiopia, rural

tag: mother's age

tag: infant's sex

tag: time post-partum

tag: parity

tag: delivery

tag: bmi

tag: bmi code

value: NORMAL

tag: mother's height (cm)

tag: companion animals

value: NO

tag: agricultural animals

value: YES

tag: molecule type

value: IgA


title: 3C_Sac_ActD_rep2

tag: genotype

tag: developmental stage

value: 30 min after the treatment with actinomycin D

tag: strain


title: RqcH-IP/total tRNA 2-1

description: Biological replicate 2 of 3 Cy3 vs 1 of 1 Atto

tag: sample type

tag: patient identifier

tag: cell line


title: 1 in 300,000 OPE mixture 24h rep1 [M3_24_1]

tag: gestation day

tag: tissue

tag: treatment

tag: time point


title: Control 24h rep3 [MC_24_3]

value: DMSO


title: Sample_24

tag: strain background

tag: genotype/variation


title: Control 24h rep4 [MC_24_4]


title: Sample_4


title: Patient 23

city: Southampton

first: JAYA

last: THOMAS

address: MP824 Somers Building, Southampton General Hospital, Tremona Road,

department: Cancer Science

country: United Kingdom

institute: University of Southampton

data_processing:
Sequenced reads were trimmed for adaptor sequence, and masked for low-complexity or low-quality sequence, then mapped to hg38 whole genome using the RSEM [Li and Dewey, 2011 BMC Bioinformat. 12:323. doi: 10.1186/1471-2105-12-323]
Un-aligned sequences were taken and aligned to the viral reference file using popular alignment tools BWA (v0.7.15-r1140) and Bowtie2 (v1.2.2).
Calculated quantitate read counts at the individual viral-gene level using Bowtie2 output and the HPV16 gtf file
Genome_build: NC_001526.2
Supplementary_files_format_and_content: raw counts

organism:
Homo sapiens
Human papillomavirus 16

source_name: whole tumour

extract_protocol:
RNA was extracted from snap-frozen tissue of 4 patients (Maxwell® RSC simplyRNA Tissue Kit(AS1340), Promega, Southampton, UK). RNA concentration and quality were analyzed using the RNA Nano Kit for the 2100 Bioanalyzer System (Agilent Technologies, Santa Clara, CA, USA).
RNA-sequencing was undertaken by Edinburgh Genomics (University of Edinburgh, Edinburgh, UK). An automated TruSeq stranded mRNA-seq library preparation from total RNA and the 137 UK). An automated TruSeq stranded mRNA-seq library preparation from total RNA and the NovaSeq sequencing-system was used (100bp paired-end; 1,750M+1,750M reads, Illumina, San Diego, CA, USA).

value: head and neck squamous cell carcinoma

tag: diagnosis

value: Oropharyngeal squamous cell carcinoma

tag: tumour site

value: Tonsil

tag: hpv16 status

value: positive

tag: tnm

value: T2 N2b M0

tag: primary treatment

value: Surgery


title: 3C_Sac_log_rep2

tag: genotype

value: Wild type

value: Log-phase cells


title: 3C_Sac_sta_rep1

tag: developmental stage

value: Stationary-phase cells


title: Control 24h rep2 [MC_24_2]

tag: strain

value: GD 13

value: limb bud

value: 24 hours


title: Sample_2

value: SCX-GFP transgenic

value: hind limb


title: Sample_1


title: Control 24h rep1 [MC_24_1]


title: Patient 16

value: T2 N1 M0


title: 1 in 300,000 OPE mixture 24h rep2 [M3_24_2]

value: 1 in 300,000 dilution of a house dust-based OPE mixture


title: Sample_3


title: 3C_Sac_ActD_rep1

value: 30 min after the treatment with actinomycin D


title: Adult Testis, Male #1

status: Public on Dec 27 2020

city: Ulsan

first: Taejoon

last: Kwon

address: 50 Unist-gil

department: Department of Biomedical Engineering

institute: Ulsan National Institute of Science and Technology

data_processing:
Clena up the adpater sequences with trimmomatic (0.39)
Map the reads to the cDNA references using kallisto (0.44.0)
Genome_build: Bombina_orientalis.a2020_08.cdna.fa.gz
Supplementary_files_format_and_content: Default output of kallisto (0.44.0)

molecule: polyA RNA

organism: Bombina orientalis

source_name: Adult Testis

extract_protocol:
Total RNA was extracted using Trizol reagent (Thermo Fisher, 15596018) according to manufacturer’s protocol. To eliminate DNA, samples were purified using PCI/Ethanol purification and lithium chloride methods.
Library preparation were performed using a TruSeq stranded mRNA sample prep kit (Illumina, 20020595).

value: Testis


title: Adult Ventral Skin, Male #1

source_name: Adult Ventral Skin

value: Ventral Skin


title: Adult Stomach, Male #1

source_name: Adult Stomach

value: Stomach


title: Adult Lung, Male #1

source_name: Adult Lung

value: Lung


title: Adult Liver, Male #1

source_name: Adult Liver

value: Liver


title: Adult Colon, Male #1

source_name: Adult Colon

value: Colon


title: Adult Dorsal Skin, Male #1

source_name: Adult Dorsal Skin

value: Dorsal Skin


title: Adult Ventral Skin, Male #3


title: Adult Dorsal Skin, Male #3


title: Patient 15

value: head and neck squamous cell carcinoma

value: Oropharyngeal squamous cell carcinoma

value: Base of Tongue

value: positive

value: T2 N2b M0

value: RT/CRT


title: Adult Ventral Skin, Male #2


title: Adult Heart, Male #1

source_name: Adult Heart

value: Heart


title: Adult Stomach, Male #2


title: 3C_Sac_log_rep1

value: Wild type

value: Log-phase cells


title: Adult Heart, Female #2


title: Adult Intestine, Male #1

source_name: Adult Intestine

value: Intestine


title: Adult Lung, Female #2


title: Patient 27

value: Tonsil

value: negative

value: T1 N2b M0

value: Surgery


title: Adult Ventral Skin, Female #1

value: Ventral Skin


title: Adult Liver, Female #2

value: Liver


title: Adult Stomach, Female #1

value: Stomach


title: Adult Intestine, Female #2


title: Adult Colon, Female #2

value: Colon


title: Adult Dorsal Skin, Female #2

value: Dorsal Skin


title: Adult Ovary, Female #1

source_name: Adult Ovary

value: Ovary


title: RqcH-IP/total tRNA 1-1

description: Biological replicate 1 of 3 Cy3 vs 1 of 1 Atto

tag: sample type

value: total lysate

value: RqcH IP


title: 1 in 300,000 OPE mixture 24h rep4 [M3_24_4]

value: GD 13

value: limb bud

value: 1 in 300,000 dilution of a house dust-based OPE mixture

value: 24 hours


title: Adult Heart, Female #1

value: Heart


title: Adult Dorsal Skin, Female #1


title: Adult Intestine, Female #1

value: Intestine


title: Adult Liver, Female #1


title: Adult Lung, Female #1

value: Lung


title: Murine utricle cells [Cell_999]

city: Nashville

first: Taha

last: Jan

state: TN

address: 2220 Pierce Ave, PRB 752

department: Otolaryngology

institute: VUMC

data_processing:
Illumina NextGen Sequencing
demultiplexing
STAR alignment v2.5.3a
read quantification: RSEM v1.3.0
Genome_build: mm10
Supplementary_files_format_and_content: csv file with raw read counts

source_name: utricle cells

extract_protocol:
RNA lysis buffer
Smart-seq2

value: Mix of C57BL/6 and FVB

tag: age

value: Wildtype

tag: well volume

tag: plate position

tag: sequencing pool

tag: enzyme

value: maxima

tag: qc outcome

value: passed


title: Murine utricle cells [Cell_996]


title: Murine utricle cells [Cell_1001]


title: Murine utricle cells [Cell_995]


title: Murine utricle cells [Cell_998]


title: Murine utricle cells [Cell_997]


title: Murine utricle cells [Cell_1000]


title: Murine utricle cells [Cell_993]


title: Murine utricle cells [Cell_994]

value: failed


title: Murine utricle cells [Cell_990]


title: Murine utricle cells [Cell_985]


title: Murine utricle cells [Cell_988]


title: Murine utricle cells [Cell_989]


title: Murine utricle cells [Cell_987]


title: Murine utricle cells [Cell_986]


title: Murine utricle cells [Cell_982]


title: Murine utricle cells [Cell_991]


title: Murine utricle cells [Cell_984]


title: Murine utricle cells [Cell_983]


title: Murine utricle cells [Cell_981]


title: Adult Colon, Female #1

tag: tissue

value: Colon


title: Murine utricle cells [Cell_980]


title: Murine utricle cells [Cell_1002]


title: Murine utricle cells [Cell_976]


title: Murine utricle cells [Cell_975]


title: Murine utricle cells [Cell_977]


title: Murine utricle cells [Cell_979]


title: Murine utricle cells [Cell_978]


title: Murine utricle cells [Cell_992]


title: Murine utricle cells [Cell_969]


title: Murine utricle cells [Cell_973]


title: Murine utricle cells [Cell_968]


title: Murine utricle cells [Cell_970]


title: Murine utricle cells [Cell_971]


title: Murine utricle cells [Cell_966]


title: Murine utricle cells [Cell_965]


title: Murine utricle cells [Cell_967]


title: Murine utricle cells [Cell_961]


title: Murine utricle cells [Cell_963]


title: Murine utricle cells [Cell_962]


title: Murine utricle cells [Cell_964]


title: Murine utricle cells [Cell_960]


title: Murine utricle cells [Cell_959]


title: Murine utricle cells [Cell_957]


title: Murine utricle cells [Cell_958]


title: Murine utricle cells [Cell_956]


title: Murine utricle cells [Cell_954]


title: Murine utricle cells [Cell_955]


title: Murine utricle cells [Cell_953]


title: Murine utricle cells [Cell_952]


title: Murine utricle cells [Cell_951]


title: Murine utricle cells [Cell_949]


title: Murine utricle cells [Cell_950]


title: Murine utricle cells [Cell_947]


title: Murine utricle cells [Cell_972]


title: Murine utricle cells [Cell_974]


title: Sample_32

source_name: SCX-GFP transgenic hind limb_E10.5

tag: strain background

tag: genotype/variation

value: SCX-GFP transgenic

value: hind limb


title: Murine utricle cells [Cell_946]


title: Murine utricle cells [Cell_944]


title: Murine utricle cells [Cell_941]


title: Murine utricle cells [Cell_942]


title: Murine utricle cells [Cell_939]


title: Murine utricle cells [Cell_938]


title: Murine utricle cells [Cell_945]


title: Murine utricle cells [Cell_940]


title: Murine utricle cells [Cell_936]


title: Murine utricle cells [Cell_937]


title: Murine utricle cells [Cell_934]


title: Murine utricle cells [Cell_932]


title: Murine utricle cells [Cell_931]


title: Murine utricle cells [Cell_935]


title: Murine utricle cells [Cell_927]


title: Murine utricle cells [Cell_933]


title: Murine utricle cells [Cell_948]


title: Murine utricle cells [Cell_930]


title: Murine utricle cells [Cell_928]


title: Murine utricle cells [Cell_923]


title: Murine utricle cells [Cell_925]


title: Murine utricle cells [Cell_922]


title: Murine utricle cells [Cell_921]


title: Murine utricle cells [Cell_920]


title: Murine utricle cells [Cell_929]


title: Murine utricle cells [Cell_943]


title: Murine utricle cells [Cell_919]


title: Murine utricle cells [Cell_917]


title: Murine utricle cells [Cell_918]


title: Murine utricle cells [Cell_915]


title: Murine utricle cells [Cell_910]


title: Murine utricle cells [Cell_912]


title: Murine utricle cells [Cell_911]


title: Murine utricle cells [Cell_914]


title: Murine utricle cells [Cell_926]


title: Murine utricle cells [Cell_908]


title: Murine utricle cells [Cell_913]


title: Murine utricle cells [Cell_901]


title: Murine utricle cells [Cell_902]


title: Murine utricle cells [Cell_924]


title: Murine utricle cells [Cell_907]


title: Murine utricle cells [Cell_894]


title: Murine utricle cells [Cell_895]


title: Murine utricle cells [Cell_905]


title: Murine utricle cells [Cell_903]


title: Murine utricle cells [Cell_904]


title: Murine utricle cells [Cell_898]


title: Murine utricle cells [Cell_899]


title: Murine utricle cells [Cell_906]


title: Murine utricle cells [Cell_897]


title: Murine utricle cells [Cell_900]


title: Murine utricle cells [Cell_896]


title: Murine utricle cells [Cell_889]


title: Murine utricle cells [Cell_891]


title: Murine utricle cells [Cell_890]


title: Murine utricle cells [Cell_892]


title: Murine utricle cells [Cell_888]


title: Murine utricle cells [Cell_886]


title: Murine utricle cells [Cell_883]


title: Murine utricle cells [Cell_885]


title: Murine utricle cells [Cell_882]


title: Murine utricle cells [Cell_916]


title: Murine utricle cells [Cell_887]


title: Murine utricle cells [Cell_909]


title: Murine utricle cells [Cell_893]


title: Murine utricle cells [Cell_880]


title: Murine utricle cells [Cell_879]


title: Murine utricle cells [Cell_873]


title: Murine utricle cells [Cell_869]


title: Murine utricle cells [Cell_875]


title: Murine utricle cells [Cell_877]


title: Murine utricle cells [Cell_872]


title: Murine utricle cells [Cell_868]


title: Murine utricle cells [Cell_878]


title: Murine utricle cells [Cell_870]


title: Murine utricle cells [Cell_865]


title: Murine utricle cells [Cell_866]


title: Murine utricle cells [Cell_859]


title: Murine utricle cells [Cell_857]


title: Murine utricle cells [Cell_858]


title: Murine utricle cells [Cell_876]


title: Murine utricle cells [Cell_884]


title: Murine utricle cells [Cell_871]


title: Murine utricle cells [Cell_862]


title: Murine utricle cells [Cell_864]


title: Murine utricle cells [Cell_861]


title: Murine utricle cells [Cell_863]


title: Murine utricle cells [Cell_881]


title: Murine utricle cells [Cell_860]


title: Murine utricle cells [Cell_856]


title: Murine utricle cells [Cell_854]


title: Murine utricle cells [Cell_853]


title: Murine utricle cells [Cell_874]


title: Murine utricle cells [Cell_867]


title: Murine utricle cells [Cell_855]


title: Murine utricle cells [Cell_850]


title: Murine utricle cells [Cell_849]


title: Murine utricle cells [Cell_852]


title: Murine utricle cells [Cell_851]


title: Murine utricle cells [Cell_843]


title: Murine utricle cells [Cell_847]


title: Murine utricle cells [Cell_844]


title: Murine utricle cells [Cell_845]


title: Murine utricle cells [Cell_840]


title: Murine utricle cells [Cell_842]


title: Murine utricle cells [Cell_838]


title: Murine utricle cells [Cell_846]


title: Murine utricle cells [Cell_837]


title: Murine utricle cells [Cell_836]


title: Murine utricle cells [Cell_841]


title: Murine utricle cells [Cell_832]


title: Murine utricle cells [Cell_839]


title: Murine utricle cells [Cell_835]


title: Murine utricle cells [Cell_833]


title: Murine utricle cells [Cell_830]


title: Murine utricle cells [Cell_829]


title: Murine utricle cells [Cell_828]


title: Murine utricle cells [Cell_831]


title: Murine utricle cells [Cell_827]


title: Murine utricle cells [Cell_834]


title: Murine utricle cells [Cell_826]


title: Murine utricle cells [Cell_825]


title: Murine utricle cells [Cell_824]


title: Murine utricle cells [Cell_848]


title: Murine utricle cells [Cell_823]


title: Murine utricle cells [Cell_821]


title: Murine utricle cells [Cell_820]


title: Murine utricle cells [Cell_822]


title: Murine utricle cells [Cell_818]


title: Murine utricle cells [Cell_816]


title: Murine utricle cells [Cell_811]


title: Murine utricle cells [Cell_810]


title: Murine utricle cells [Cell_815]


title: Murine utricle cells [Cell_809]


title: Murine utricle cells [Cell_812]


title: Murine utricle cells [Cell_804]


title: Murine utricle cells [Cell_808]


title: Murine utricle cells [Cell_801]


title: Murine utricle cells [Cell_802]


title: Murine utricle cells [Cell_800]


title: Murine utricle cells [Cell_799]


title: Murine utricle cells [Cell_798]


title: Murine utricle cells [Cell_797]


title: Murine utricle cells [Cell_803]


title: Murine utricle cells [Cell_796]


title: Murine utricle cells [Cell_795]


title: Murine utricle cells [Cell_814]


title: Murine utricle cells [Cell_817]


title: Murine utricle cells [Cell_793]


title: Murine utricle cells [Cell_792]


title: Murine utricle cells [Cell_794]


title: Murine utricle cells [Cell_789]


title: Murine utricle cells [Cell_819]


title: Murine utricle cells [Cell_791]


title: Murine utricle cells [Cell_813]


title: Murine utricle cells [Cell_807]


title: Murine utricle cells [Cell_788]


title: Murine utricle cells [Cell_806]


title: Murine utricle cells [Cell_787]


title: Murine utricle cells [Cell_785]


title: Murine utricle cells [Cell_784]


title: Murine utricle cells [Cell_786]


title: Murine utricle cells [Cell_782]


title: Murine utricle cells [Cell_781]


title: Murine utricle cells [Cell_783]


title: Murine utricle cells [Cell_805]


title: Murine utricle cells [Cell_780]


title: Murine utricle cells [Cell_776]


title: Murine utricle cells [Cell_779]


title: Murine utricle cells [Cell_774]


title: Murine utricle cells [Cell_777]


title: Murine utricle cells [Cell_775]


title: Murine utricle cells [Cell_773]


title: Murine utricle cells [Cell_772]


title: Murine utricle cells [Cell_769]


title: Murine utricle cells [Cell_771]


title: Murine utricle cells [Cell_768]


title: Murine utricle cells [Cell_767]


title: Murine utricle cells [Cell_766]


title: Murine utricle cells [Cell_764]


title: Murine utricle cells [Cell_762]


title: Murine utricle cells [Cell_761]


title: Murine utricle cells [Cell_765]


title: Murine utricle cells [Cell_759]


title: Murine utricle cells [Cell_763]


title: Murine utricle cells [Cell_758]


title: Murine utricle cells [Cell_757]


title: Murine utricle cells [Cell_760]


title: Murine utricle cells [Cell_754]


title: Murine utricle cells [Cell_753]


title: Murine utricle cells [Cell_755]


title: Murine utricle cells [Cell_756]


title: Murine utricle cells [Cell_751]


title: Murine utricle cells [Cell_748]


title: Murine utricle cells [Cell_747]


title: Murine utricle cells [Cell_752]


title: Murine utricle cells [Cell_746]


title: Murine utricle cells [Cell_750]


title: Murine utricle cells [Cell_770]


title: Murine utricle cells [Cell_749]


title: Murine utricle cells [Cell_744]


title: Murine utricle cells [Cell_742]


title: Murine utricle cells [Cell_745]


title: Murine utricle cells [Cell_743]


title: Murine utricle cells [Cell_740]


title: Murine utricle cells [Cell_739]


title: Murine utricle cells [Cell_738]


title: Murine utricle cells [Cell_736]


title: Murine utricle cells [Cell_735]


title: Murine utricle cells [Cell_737]


title: Murine utricle cells [Cell_733]


title: Murine utricle cells [Cell_732]


title: Murine utricle cells [Cell_730]


title: Murine utricle cells [Cell_727]


title: Murine utricle cells [Cell_726]


title: Murine utricle cells [Cell_724]


title: Murine utricle cells [Cell_723]


title: Murine utricle cells [Cell_725]


title: Murine utricle cells [Cell_719]


title: Murine utricle cells [Cell_720]


title: Murine utricle cells [Cell_721]


title: Murine utricle cells [Cell_731]


title: Murine utricle cells [Cell_741]


title: Murine utricle cells [Cell_716]


title: Murine utricle cells [Cell_717]


title: Murine utricle cells [Cell_714]


title: Murine utricle cells [Cell_713]


title: Murine utricle cells [Cell_715]


title: Murine utricle cells [Cell_711]


title: Murine utricle cells [Cell_710]


title: Murine utricle cells [Cell_712]


title: Murine utricle cells [Cell_709]


title: Murine utricle cells [Cell_734]


title: Murine utricle cells [Cell_728]


title: Murine utricle cells [Cell_729]


title: Murine utricle cells [Cell_707]


title: Murine utricle cells [Cell_706]


title: Murine utricle cells [Cell_708]


title: Murine utricle cells [Cell_705]


title: Murine utricle cells [Cell_722]


title: Murine utricle cells [Cell_701]


title: Murine utricle cells [Cell_702]


title: Murine utricle cells [Cell_704]


title: Murine utricle cells [Cell_703]


title: Murine utricle cells [Cell_718]


title: Murine utricle cells [Cell_698]


title: Murine utricle cells [Cell_699]


title: Murine utricle cells [Cell_697]


title: Murine utricle cells [Cell_696]


title: Murine utricle cells [Cell_695]


title: Murine utricle cells [Cell_694]


title: Murine utricle cells [Cell_693]


title: Murine utricle cells [Cell_692]


title: Murine utricle cells [Cell_700]


title: Murine utricle cells [Cell_690]


title: Murine utricle cells [Cell_689]


title: Murine utricle cells [Cell_691]


title: Murine utricle cells [Cell_688]


title: Murine utricle cells [Cell_686]


title: Murine utricle cells [Cell_685]


title: Murine utricle cells [Cell_684]


title: Murine utricle cells [Cell_682]


title: Murine utricle cells [Cell_680]


title: Murine utricle cells [Cell_679]


title: Murine utricle cells [Cell_683]


title: Murine utricle cells [Cell_678]


title: Murine utricle cells [Cell_676]


title: Murine utricle cells [Cell_674]


title: Murine utricle cells [Cell_677]


title: Murine utricle cells [Cell_673]


title: Murine utricle cells [Cell_672]


title: Murine utricle cells [Cell_675]


title: Murine utricle cells [Cell_671]


title: Murine utricle cells [Cell_670]


title: Murine utricle cells [Cell_669]


title: Murine utricle cells [Cell_666]


title: Murine utricle cells [Cell_667]


title: Murine utricle cells [Cell_665]


title: Murine utricle cells [Cell_668]


title: Murine utricle cells [Cell_687]


title: Murine utricle cells [Cell_663]


title: Murine utricle cells [Cell_664]


title: Murine utricle cells [Cell_662]


title: Murine utricle cells [Cell_681]


title: Murine utricle cells [Cell_659]


title: Murine utricle cells [Cell_660]


title: Murine utricle cells [Cell_661]


title: Murine utricle cells [Cell_658]


title: Murine utricle cells [Cell_656]


title: Murine utricle cells [Cell_657]


title: Murine utricle cells [Cell_654]


title: Murine utricle cells [Cell_652]


title: Murine utricle cells [Cell_653]


title: Murine utricle cells [Cell_651]


title: Murine utricle cells [Cell_647]


title: Murine utricle cells [Cell_649]


title: Murine utricle cells [Cell_655]


title: Murine utricle cells [Cell_645]


title: Murine utricle cells [Cell_648]


title: Murine utricle cells [Cell_644]


title: Murine utricle cells [Cell_642]


title: Murine utricle cells [Cell_643]


title: Murine utricle cells [Cell_640]


title: Murine utricle cells [Cell_641]


title: Murine utricle cells [Cell_639]


title: Murine utricle cells [Cell_637]


title: Murine utricle cells [Cell_634]


title: Murine utricle cells [Cell_638]


title: Murine utricle cells [Cell_636]


title: Murine utricle cells [Cell_630]


title: Murine utricle cells [Cell_628]


title: Murine utricle cells [Cell_627]


title: Murine utricle cells [Cell_633]


title: Murine utricle cells [Cell_629]


title: Murine utricle cells [Cell_632]


title: Murine utricle cells [Cell_650]


title: Murine utricle cells [Cell_631]


title: Murine utricle cells [Cell_625]


title: Murine utricle cells [Cell_626]


title: Murine utricle cells [Cell_646]


title: Murine utricle cells [Cell_624]


title: Murine utricle cells [Cell_621]


title: Murine utricle cells [Cell_620]


title: Murine utricle cells [Cell_619]


title: Murine utricle cells [Cell_622]


title: Murine utricle cells [Cell_618]


title: Murine utricle cells [Cell_615]


title: Murine utricle cells [Cell_635]


title: Murine utricle cells [Cell_617]


title: Murine utricle cells [Cell_616]


title: Murine utricle cells [Cell_613]


title: Murine utricle cells [Cell_610]


title: Murine utricle cells [Cell_612]


title: Murine utricle cells [Cell_609]


title: Murine utricle cells [Cell_790]


title: Murine utricle cells [Cell_608]


title: Murine utricle cells [Cell_611]


title: Murine utricle cells [Cell_605]


title: Murine utricle cells [Cell_599]


title: Murine utricle cells [Cell_604]


title: Murine utricle cells [Cell_606]


title: Murine utricle cells [Cell_598]


title: Murine utricle cells [Cell_601]


title: Murine utricle cells [Cell_623]


title: Murine utricle cells [Cell_607]


title: Murine utricle cells [Cell_597]


title: Murine utricle cells [Cell_602]


title: Murine utricle cells [Cell_600]


title: Murine utricle cells [Cell_596]


title: Murine utricle cells [Cell_595]


title: Murine utricle cells [Cell_594]


title: Murine utricle cells [Cell_614]


title: Murine utricle cells [Cell_591]


title: Murine utricle cells [Cell_590]


title: Murine utricle cells [Cell_588]


title: Murine utricle cells [Cell_587]


title: Murine utricle cells [Cell_589]


title: Murine utricle cells [Cell_586]


title: Murine utricle cells [Cell_603]


title: Murine utricle cells [Cell_576]


title: Murine utricle cells [Cell_582]


title: Murine utricle cells [Cell_578]


title: Murine utricle cells [Cell_577]


title: Murine utricle cells [Cell_585]


title: Murine utricle cells [Cell_570]


title: Murine utricle cells [Cell_573]

value: smartscribe


title: Murine utricle cells [Cell_575]


title: Murine utricle cells [Cell_592]


title: Murine utricle cells [Cell_569]


title: Murine utricle cells [Cell_579]


title: Murine utricle cells [Cell_593]


title: Murine utricle cells [Cell_580]


title: Murine utricle cells [Cell_581]


title: Murine utricle cells [Cell_571]


title: Murine utricle cells [Cell_583]


title: Murine utricle cells [Cell_568]


title: Murine utricle cells [Cell_564]


title: Murine utricle cells [Cell_574]


title: Murine utricle cells [Cell_566]


title: Murine utricle cells [Cell_562]


title: Murine utricle cells [Cell_567]


title: Murine utricle cells [Cell_584]


title: Murine utricle cells [Cell_559]


title: Murine utricle cells [Cell_560]


title: Murine utricle cells [Cell_572]


title: Murine utricle cells [Cell_558]


title: Murine utricle cells [Cell_556]


title: Murine utricle cells [Cell_555]


title: Murine utricle cells [Cell_552]


title: Murine utricle cells [Cell_551]


title: Murine utricle cells [Cell_557]


title: Murine utricle cells [Cell_550]


title: Murine utricle cells [Cell_545]


title: Murine utricle cells [Cell_561]


title: Murine utricle cells [Cell_547]


title: Murine utricle cells [Cell_542]


title: Murine utricle cells [Cell_553]


title: Murine utricle cells [Cell_565]


title: Murine utricle cells [Cell_549]


title: Murine utricle cells [Cell_544]


title: Murine utricle cells [Cell_546]


title: Murine utricle cells [Cell_543]


title: Murine utricle cells [Cell_539]


title: Murine utricle cells [Cell_538]


title: Murine utricle cells [Cell_537]


title: Murine utricle cells [Cell_535]


title: Murine utricle cells [Cell_548]


title: Murine utricle cells [Cell_563]


title: Murine utricle cells [Cell_534]


title: Murine utricle cells [Cell_540]


title: Murine utricle cells [Cell_541]


title: Murine utricle cells [Cell_536]


title: Murine utricle cells [Cell_554]


title: Murine utricle cells [Cell_533]


title: Murine utricle cells [Cell_531]


title: Murine utricle cells [Cell_532]


title: Murine utricle cells [Cell_530]


title: Murine utricle cells [Cell_529]


title: Murine utricle cells [Cell_527]


title: Murine utricle cells [Cell_524]


title: Murine utricle cells [Cell_525]


title: Murine utricle cells [Cell_523]


title: Murine utricle cells [Cell_522]


title: Murine utricle cells [Cell_526]


title: Murine utricle cells [Cell_519]


title: Murine utricle cells [Cell_520]


title: Murine utricle cells [Cell_521]


title: Murine utricle cells [Cell_512]


title: Murine utricle cells [Cell_516]


title: Murine utricle cells [Cell_513]


title: Murine utricle cells [Cell_511]


title: Murine utricle cells [Cell_515]


title: Murine utricle cells [Cell_514]


title: Murine utricle cells [Cell_507]


title: Murine utricle cells [Cell_517]


title: Murine utricle cells [Cell_508]


title: Murine utricle cells [Cell_518]


title: Murine utricle cells [Cell_510]


title: Murine utricle cells [Cell_506]


title: Murine utricle cells [Cell_505]


title: Murine utricle cells [Cell_504]


title: Murine utricle cells [Cell_528]


title: Murine utricle cells [Cell_502]


title: Murine utricle cells [Cell_500]


title: Murine utricle cells [Cell_509]


title: Murine utricle cells [Cell_499]


title: Murine utricle cells [Cell_498]


title: Murine utricle cells [Cell_496]


title: Murine utricle cells [Cell_494]


title: Murine utricle cells [Cell_495]


title: Murine utricle cells [Cell_492]


title: Murine utricle cells [Cell_490]


title: Murine utricle cells [Cell_491]


title: Murine utricle cells [Cell_489]


title: Murine utricle cells [Cell_485]


title: Murine utricle cells [Cell_484]


title: Murine utricle cells [Cell_481]


title: Murine utricle cells [Cell_486]


title: Murine utricle cells [Cell_482]


title: Murine utricle cells [Cell_488]


title: Murine utricle cells [Cell_480]


title: Murine utricle cells [Cell_497]


title: Murine utricle cells [Cell_479]


title: Murine utricle cells [Cell_478]


title: Murine utricle cells [Cell_501]


title: Murine utricle cells [Cell_477]


title: Murine utricle cells [Cell_487]


title: Murine utricle cells [Cell_503]


title: Murine utricle cells [Cell_476]


title: Murine utricle cells [Cell_475]


title: Murine utricle cells [Cell_493]


title: Murine utricle cells [Cell_473]


title: Murine utricle cells [Cell_470]


title: Murine utricle cells [Cell_471]


title: Murine utricle cells [Cell_472]


title: Murine utricle cells [Cell_469]


title: Murine utricle cells [Cell_467]


title: Murine utricle cells [Cell_474]


title: Murine utricle cells [Cell_483]


title: Murine utricle cells [Cell_466]


title: Murine utricle cells [Cell_464]


title: Murine utricle cells [Cell_459]


title: Murine utricle cells [Cell_460]


title: Murine utricle cells [Cell_457]


title: Murine utricle cells [Cell_465]


title: Murine utricle cells [Cell_463]


title: Murine utricle cells [Cell_456]


title: Murine utricle cells [Cell_453]


title: Murine utricle cells [Cell_458]


title: Murine utricle cells [Cell_454]


title: Murine utricle cells [Cell_449]


title: Murine utricle cells [Cell_462]


title: Murine utricle cells [Cell_451]


title: Murine utricle cells [Cell_461]


title: Murine utricle cells [Cell_448]


title: Murine utricle cells [Cell_452]


title: Murine utricle cells [Cell_447]


title: Murine utricle cells [Cell_446]


title: Murine utricle cells [Cell_450]


title: Murine utricle cells [Cell_443]


title: Murine utricle cells [Cell_445]


title: Murine utricle cells [Cell_444]


title: Murine utricle cells [Cell_442]


title: Murine utricle cells [Cell_441]


title: Murine utricle cells [Cell_439]


title: Murine utricle cells [Cell_438]


title: Murine utricle cells [Cell_437]


title: Murine utricle cells [Cell_455]


title: Murine utricle cells [Cell_435]


title: Murine utricle cells [Cell_433]


title: Murine utricle cells [Cell_429]


title: Murine utricle cells [Cell_468]


title: Murine utricle cells [Cell_430]


title: Murine utricle cells [Cell_431]


title: Murine utricle cells [Cell_440]


title: Murine utricle cells [Cell_428]


title: Murine utricle cells [Cell_426]


title: Murine utricle cells [Cell_436]


title: Murine utricle cells [Cell_423]


title: Murine utricle cells [Cell_422]


title: Murine utricle cells [Cell_421]


title: Murine utricle cells [Cell_434]


title: Murine utricle cells [Cell_425]


title: Murine utricle cells [Cell_420]


title: Murine utricle cells [Cell_427]


title: Murine utricle cells [Cell_419]


title: Murine utricle cells [Cell_416]


title: Murine utricle cells [Cell_417]


title: Murine utricle cells [Cell_414]


title: Murine utricle cells [Cell_413]


title: Murine utricle cells [Cell_415]


title: Murine utricle cells [Cell_424]


title: Murine utricle cells [Cell_432]


title: Murine utricle cells [Cell_411]


title: Murine utricle cells [Cell_409]


title: Murine utricle cells [Cell_410]


title: Murine utricle cells [Cell_400]


title: Murine utricle cells [Cell_405]


title: Murine utricle cells [Cell_402]


title: Murine utricle cells [Cell_404]


title: Murine utricle cells [Cell_412]


title: Murine utricle cells [Cell_406]


title: Murine utricle cells [Cell_401]


title: Murine utricle cells [Cell_418]


title: Murine utricle cells [Cell_398]


title: Murine utricle cells [Cell_399]


title: Murine utricle cells [Cell_397]


title: Murine utricle cells [Cell_392]


title: Murine utricle cells [Cell_393]


title: Murine utricle cells [Cell_396]


title: Murine utricle cells [Cell_391]


title: Murine utricle cells [Cell_390]


title: Murine utricle cells [Cell_388]


title: Murine utricle cells [Cell_386]


title: Murine utricle cells [Cell_387]


title: Murine utricle cells [Cell_389]


title: Murine utricle cells [Cell_385]


title: Murine utricle cells [Cell_394]


title: Murine utricle cells [Cell_384]


title: Murine utricle cells [Cell_383]


title: Murine utricle cells [Cell_403]


title: Murine utricle cells [Cell_382]


title: Murine utricle cells [Cell_407]


title: Murine utricle cells [Cell_408]


title: Murine utricle cells [Cell_376]


title: Murine utricle cells [Cell_379]


title: Murine utricle cells [Cell_377]


title: Murine utricle cells [Cell_381]


title: Murine utricle cells [Cell_375]


title: Murine utricle cells [Cell_395]


title: Murine utricle cells [Cell_378]


title: Murine utricle cells [Cell_370]


title: Murine utricle cells [Cell_373]


title: Murine utricle cells [Cell_372]


title: Murine utricle cells [Cell_369]


title: Murine utricle cells [Cell_374]


title: Murine utricle cells [Cell_368]


title: Murine utricle cells [Cell_365]


title: Murine utricle cells [Cell_366]


title: Murine utricle cells [Cell_364]


title: Murine utricle cells [Cell_362]


title: Murine utricle cells [Cell_367]


title: Murine utricle cells [Cell_363]


title: Murine utricle cells [Cell_361]


title: Murine utricle cells [Cell_359]


title: Murine utricle cells [Cell_354]


title: Murine utricle cells [Cell_356]


title: Murine utricle cells [Cell_351]


title: Murine utricle cells [Cell_353]


title: Murine utricle cells [Cell_355]


title: Murine utricle cells [Cell_357]


title: Murine utricle cells [Cell_350]


title: Murine utricle cells [Cell_349]


title: Murine utricle cells [Cell_348]


title: Murine utricle cells [Cell_358]


title: Murine utricle cells [Cell_380]


title: Murine utricle cells [Cell_346]


title: Murine utricle cells [Cell_345]


title: Murine utricle cells [Cell_360]


title: Murine utricle cells [Cell_352]


title: Murine utricle cells [Cell_341]


title: Murine utricle cells [Cell_335]


title: Murine utricle cells [Cell_339]


title: Murine utricle cells [Cell_343]


title: Murine utricle cells [Cell_340]


title: Murine utricle cells [Cell_337]


title: Murine utricle cells [Cell_338]


title: Murine utricle cells [Cell_336]


title: Murine utricle cells [Cell_342]


title: Murine utricle cells [Cell_334]


title: Murine utricle cells [Cell_371]


title: Murine utricle cells [Cell_332]


title: Murine utricle cells [Cell_333]


title: Murine utricle cells [Cell_331]


title: Murine utricle cells [Cell_329]


title: Murine utricle cells [Cell_330]


title: Murine utricle cells [Cell_328]


title: Murine utricle cells [Cell_344]


title: Murine utricle cells [Cell_326]


title: Murine utricle cells [Cell_324]


title: Murine utricle cells [Cell_347]


title: Murine utricle cells [Cell_327]


title: Murine utricle cells [Cell_322]


title: Murine utricle cells [Cell_321]


title: Murine utricle cells [Cell_323]


title: Murine utricle cells [Cell_319]


title: Murine utricle cells [Cell_318]


title: Murine utricle cells [Cell_325]


title: Murine utricle cells [Cell_778]


title: Murine utricle cells [Cell_296]


title: Murine utricle cells [Cell_309]


title: Murine utricle cells [Cell_301]


title: Murine utricle cells [Cell_297]


title: Murine utricle cells [Cell_303]


title: Murine utricle cells [Cell_304]


title: Murine utricle cells [Cell_308]


title: Murine utricle cells [Cell_317]


title: Murine utricle cells [Cell_313]


title: Murine utricle cells [Cell_298]


title: Murine utricle cells [Cell_300]


title: Murine utricle cells [Cell_310]


title: Murine utricle cells [Cell_312]


title: Murine utricle cells [Cell_314]


title: Murine utricle cells [Cell_306]


title: Murine utricle cells [Cell_316]


title: Murine utricle cells [Cell_307]


title: Murine utricle cells [Cell_315]


title: Murine utricle cells [Cell_295]


title: Murine utricle cells [Cell_320]


title: Murine utricle cells [Cell_311]


title: Murine utricle cells [Cell_305]


title: Murine utricle cells [Cell_292]


title: Murine utricle cells [Cell_302]


title: Murine utricle cells [Cell_291]


title: Murine utricle cells [Cell_290]


title: Murine utricle cells [Cell_294]


title: Murine utricle cells [Cell_299]


title: Murine utricle cells [Cell_293]


title: Murine utricle cells [Cell_287]


title: Murine utricle cells [Cell_286]


title: Murine utricle cells [Cell_288]


title: Murine utricle cells [Cell_280]


title: Murine utricle cells [Cell_289]


title: Murine utricle cells [Cell_283]


title: Murine utricle cells [Cell_284]


title: Murine utricle cells [Cell_276]


title: Murine utricle cells [Cell_281]


title: Murine utricle cells [Cell_285]


title: Murine utricle cells [Cell_274]


title: Murine utricle cells [Cell_278]


title: Murine utricle cells [Cell_270]


title: Murine utricle cells [Cell_279]


title: Murine utricle cells [Cell_277]


title: Murine utricle cells [Cell_272]


title: Murine utricle cells [Cell_269]


title: Murine utricle cells [Cell_275]


title: Murine utricle cells [Cell_282]


title: Murine utricle cells [Cell_268]


title: Murine utricle cells [Cell_267]


title: Murine utricle cells [Cell_266]


title: Murine utricle cells [Cell_263]


title: Murine utricle cells [Cell_264]


title: Murine utricle cells [Cell_265]


title: Murine utricle cells [Cell_262]


title: Murine utricle cells [Cell_261]


title: Murine utricle cells [Cell_273]


title: Murine utricle cells [Cell_271]


title: Murine utricle cells [Cell_256]


title: Murine utricle cells [Cell_258]


title: Murine utricle cells [Cell_260]


title: Murine utricle cells [Cell_257]


title: Murine utricle cells [Cell_255]


title: Murine utricle cells [Cell_259]


title: Murine utricle cells [Cell_244]


title: Murine utricle cells [Cell_241]


title: Murine utricle cells [Cell_250]


title: Murine utricle cells [Cell_248]


title: Murine utricle cells [Cell_253]


title: Murine utricle cells [Cell_247]


title: Murine utricle cells [Cell_240]


title: Murine utricle cells [Cell_251]


title: Murine utricle cells [Cell_249]


title: Murine utricle cells [Cell_246]


title: Murine utricle cells [Cell_242]


title: Murine utricle cells [Cell_239]


title: Murine utricle cells [Cell_238]


title: Murine utricle cells [Cell_237]


title: Murine utricle cells [Cell_235]


title: Murine utricle cells [Cell_234]


title: Murine utricle cells [Cell_233]


title: Murine utricle cells [Cell_252]


title: Murine utricle cells [Cell_232]


title: Murine utricle cells [Cell_231]


title: Murine utricle cells [Cell_254]


title: Murine utricle cells [Cell_243]


title: Murine utricle cells [Cell_245]


title: Murine utricle cells [Cell_230]


title: Murine utricle cells [Cell_226]


title: Murine utricle cells [Cell_228]


title: Murine utricle cells [Cell_225]


title: Murine utricle cells [Cell_227]


title: Murine utricle cells [Cell_221]


title: Murine utricle cells [Cell_229]


title: Murine utricle cells [Cell_222]


title: Murine utricle cells [Cell_219]


title: Murine utricle cells [Cell_218]


title: Murine utricle cells [Cell_216]


title: Murine utricle cells [Cell_223]


title: Murine utricle cells [Cell_220]


title: Murine utricle cells [Cell_224]


title: Murine utricle cells [Cell_236]


title: Murine utricle cells [Cell_214]


title: Murine utricle cells [Cell_215]


title: Murine utricle cells [Cell_213]


title: Murine utricle cells [Cell_211]


title: Murine utricle cells [Cell_210]


title: Murine utricle cells [Cell_212]


title: Murine utricle cells [Cell_209]


title: Murine utricle cells [Cell_208]


title: Murine utricle cells [Cell_206]


title: Murine utricle cells [Cell_204]


title: Murine utricle cells [Cell_207]


title: Murine utricle cells [Cell_205]


title: Murine utricle cells [Cell_203]


title: Murine utricle cells [Cell_202]


title: Murine utricle cells [Cell_199]


title: Murine utricle cells [Cell_200]


title: Murine utricle cells [Cell_201]


title: Murine utricle cells [Cell_196]


title: Murine utricle cells [Cell_194]


title: Murine utricle cells [Cell_217]


title: Murine utricle cells [Cell_195]


title: Murine utricle cells [Cell_197]


title: Murine utricle cells [Cell_188]


title: Murine utricle cells [Cell_191]


title: Murine utricle cells [Cell_198]


title: Murine utricle cells [Cell_189]


title: Murine utricle cells [Cell_190]


title: Murine utricle cells [Cell_187]


title: Murine utricle cells [Cell_193]


title: Murine utricle cells [Cell_183]


title: Murine utricle cells [Cell_184]


title: Murine utricle cells [Cell_182]


title: Murine utricle cells [Cell_185]


title: Murine utricle cells [Cell_192]


title: Murine utricle cells [Cell_181]


title: Murine utricle cells [Cell_179]


title: Murine utricle cells [Cell_178]


title: Murine utricle cells [Cell_177]


title: Murine utricle cells [Cell_176]


title: Murine utricle cells [Cell_175]


title: Murine utricle cells [Cell_174]


title: Murine utricle cells [Cell_173]


title: Murine utricle cells [Cell_171]


title: Murine utricle cells [Cell_186]


title: Murine utricle cells [Cell_172]


title: Murine utricle cells [Cell_166]


title: Murine utricle cells [Cell_169]


title: Murine utricle cells [Cell_167]


title: Murine utricle cells [Cell_168]


title: Murine utricle cells [Cell_162]


title: Murine utricle cells [Cell_165]


title: Murine utricle cells [Cell_157]


title: Murine utricle cells [Cell_159]


title: Murine utricle cells [Cell_180]


title: Murine utricle cells [Cell_164]


title: Murine utricle cells [Cell_161]


title: Murine utricle cells [Cell_163]


title: Murine utricle cells [Cell_160]


title: Murine utricle cells [Cell_154]


title: Murine utricle cells [Cell_156]


title: Murine utricle cells [Cell_153]


title: Murine utricle cells [Cell_155]


title: Murine utricle cells [Cell_152]


title: Murine utricle cells [Cell_151]


title: Murine utricle cells [Cell_149]


title: Murine utricle cells [Cell_147]


title: Murine utricle cells [Cell_145]


title: Murine utricle cells [Cell_170]


title: Murine utricle cells [Cell_150]


title: Murine utricle cells [Cell_144]


title: Murine utricle cells [Cell_143]


title: Murine utricle cells [Cell_142]


title: Murine utricle cells [Cell_148]


title: Murine utricle cells [Cell_158]


title: Murine utricle cells [Cell_141]


title: Murine utricle cells [Cell_138]


title: Murine utricle cells [Cell_146]


title: Murine utricle cells [Cell_140]


title: Murine utricle cells [Cell_139]


title: Murine utricle cells [Cell_135]


title: Murine utricle cells [Cell_136]


title: Murine utricle cells [Cell_134]


title: Murine utricle cells [Cell_137]


title: Murine utricle cells [Cell_127]


title: Murine utricle cells [Cell_125]


title: Murine utricle cells [Cell_133]


title: Murine utricle cells [Cell_128]


title: Murine utricle cells [Cell_129]


title: Murine utricle cells [Cell_124]


title: Murine utricle cells [Cell_122]


title: Murine utricle cells [Cell_123]


title: Murine utricle cells [Cell_126]


title: Murine utricle cells [Cell_121]


title: Murine utricle cells [Cell_130]


title: Murine utricle cells [Cell_120]


title: Murine utricle cells [Cell_119]


title: Murine utricle cells [Cell_115]


title: Murine utricle cells [Cell_118]


title: Murine utricle cells [Cell_116]


title: Murine utricle cells [Cell_117]


title: Murine utricle cells [Cell_113]


title: Murine utricle cells [Cell_114]


title: Murine utricle cells [Cell_132]


title: Murine utricle cells [Cell_131]


title: Murine utricle cells [Cell_111]


title: Murine utricle cells [Cell_112]


title: Murine utricle cells [Cell_109]


title: Murine utricle cells [Cell_110]


title: Murine utricle cells [Cell_106]


title: Murine utricle cells [Cell_108]


title: Murine utricle cells [Cell_105]


title: Murine utricle cells [Cell_107]


title: Murine utricle cells [Cell_104]


title: Murine utricle cells [Cell_103]


title: Murine utricle cells [Cell_100]


title: Murine utricle cells [Cell_101]


title: Murine utricle cells [Cell_98]


title: Murine utricle cells [Cell_96]


title: Murine utricle cells [Cell_102]


title: Murine utricle cells [Cell_97]


title: Murine utricle cells [Cell_95]


title: Murine utricle cells [Cell_93]


title: Murine utricle cells [Cell_92]


title: Murine utricle cells [Cell_94]


title: Murine utricle cells [Cell_91]


title: Murine utricle cells [Cell_88]


title: Murine utricle cells [Cell_89]


title: Murine utricle cells [Cell_90]


title: Murine utricle cells [Cell_87]


title: Murine utricle cells [Cell_76]


title: Murine utricle cells [Cell_83]


title: Murine utricle cells [Cell_84]


title: Murine utricle cells [Cell_79]


title: Murine utricle cells [Cell_86]


title: Murine utricle cells [Cell_80]


title: Murine utricle cells [Cell_75]


title: Murine utricle cells [Cell_77]


title: Murine utricle cells [Cell_85]


title: Murine utricle cells [Cell_82]


title: Murine utricle cells [Cell_99]


title: Murine utricle cells [Cell_69]


title: Murine utricle cells [Cell_68]


title: Murine utricle cells [Cell_73]


title: Murine utricle cells [Cell_70]


title: Murine utricle cells [Cell_67]


title: Murine utricle cells [Cell_71]


title: Murine utricle cells [Cell_66]


title: Murine utricle cells [Cell_64]


title: Murine utricle cells [Cell_62]


title: Murine utricle cells [Cell_63]


title: Murine utricle cells [Cell_61]


title: Murine utricle cells [Cell_60]


title: Murine utricle cells [Cell_59]


title: Murine utricle cells [Cell_58]


title: Murine utricle cells [Cell_81]


title: Murine utricle cells [Cell_78]


title: Murine utricle cells [Cell_56]


title: Murine utricle cells [Cell_49]


title: Murine utricle cells [Cell_47]


title: Murine utricle cells [Cell_55]


title: Murine utricle cells [Cell_54]


title: Murine utricle cells [Cell_72]


title: Murine utricle cells [Cell_42]


title: Murine utricle cells [Cell_74]


title: Murine utricle cells [Cell_57]


title: Murine utricle cells [Cell_44]


title: Murine utricle cells [Cell_45]


title: Murine utricle cells [Cell_41]


title: Murine utricle cells [Cell_53]


title: Murine utricle cells [Cell_50]


title: Murine utricle cells [Cell_65]


title: Murine utricle cells [Cell_51]


title: Murine utricle cells [Cell_37]


title: Murine utricle cells [Cell_52]


title: Murine utricle cells [Cell_38]


title: Murine utricle cells [Cell_39]


title: Murine utricle cells [Cell_36]


title: Murine utricle cells [Cell_35]


title: Murine utricle cells [Cell_40]


title: Murine utricle cells [Cell_33]


title: Murine utricle cells [Cell_46]


title: Murine utricle cells [Cell_34]


title: Murine utricle cells [Cell_48]


title: Murine utricle cells [Cell_32]


title: Murine utricle cells [Cell_31]


title: Murine utricle cells [Cell_30]


title: Murine utricle cells [Cell_27]


title: Murine utricle cells [Cell_28]


title: Murine utricle cells [Cell_29]


title: Murine utricle cells [Cell_43]


title: Murine utricle cells [Cell_26]


title: Murine utricle cells [Cell_25]


title: Murine utricle cells [Cell_24]


title: Murine utricle cells [Cell_23]


title: Murine utricle cells [Cell_21]


title: Murine utricle cells [Cell_22]


title: Murine utricle cells [Cell_16]


title: Murine utricle cells [Cell_20]


title: Murine utricle cells [Cell_18]


title: Murine utricle cells [Cell_17]


title: Murine utricle cells [Cell_14]


title: Murine utricle cells [Cell_11]


title: Murine utricle cells [Cell_19]


title: Murine utricle cells [Cell_8]


title: Murine utricle cells [Cell_10]


title: Murine utricle cells [Cell_9]


title: Murine utricle cells [Cell_6]


title: Murine utricle cells [Cell_5]


title: Murine utricle cells [Cell_3]


title: Murine utricle cells [Cell_12]


title: Murine utricle cells [Cell_2]


title: Murine utricle cells [Cell_1]


title: Murine utricle cells [Cell_15]