title: TP0001651F04_4_1.000000uM_DMEM_6h_TC00283171_B13

description:
TP0001651F04_4_1.000000uM_DMEM_6h
TC00283171_B13

value: 6h exposure of 1 uM of Fulvestrant

value: Fulvestrant

value: 1 uM


title: TP0001651G01_5_3.000000uM_DMEM_6h_TC00283171_B10

status: Public on Jan 25 2021

type: SRA

city: RTP

first: Logan

middle: J

last: Everett

state: North Carolina

address: 109 T.W. Alexander Dr

department: Office of Research and Development

country: USA

institute: U.S. Environmental Protection Agency

description:
TP0001651G01_5_3.000000uM_DMEM_6h
TC00283171_B10

library_source: transcriptomic

data_processing:
[Read alignment]  Each FASTQ file was aligned to the probe sequences in the hWTv1 assay using HISAT2 v2.1.0 with spliced alignment disabled.
[Probe counts]  Aligned reads in SAM format were processed with SAMtools v1.9 to compute the number of uniquely aligned reads for each probe. Probe counts and associated meta-data for each well were stored for analysis using MongoDB v3.6.14.
Genome_build: hWTv1
Supplementary_files_format_and_content: httr_mcf7_pilot_count_data.csv - processed data provided as a single table of counts for all probes x all samples
hWTv1_mcf7_probes.csv - contains the targeted probes for the TempO-seq assay

molecule: total RNA

organism: Homo sapiens

source_name: MCF7 Cells

growth_protocol: Five vials of cryopreserved MCF7 (HTB-22TM) cells were purchased from American Tissue Culture Collection, designated as passage 0 (P0) and stored in vapor phase liquid nitrogen prior to initial thawing and expansion. A passage 3 (P3) MCF7 cryostock was generated by thawing and pooling all five original source vials and culturing through three consecutive passages in complete growth medium (DMEM + 10% FBS + 1% PSG). At each passage, cells from different culture vessels were pooled prior to re-seeding for subsequent expansion. At P3, cells were cryopreserved at 4 million cells per mL in complete growth medium + 5% DMSO according to manufacturer’s protocol. MCF7 cultures used in all phases of this study were maintained in humidified incubators with 5% CO2 atmosphere and internal temperature of 37°C. For chemical screening, MCF7 cells were thawed and subjected to a uniform expansion protocol from P3 to P6 through increasingly larger sizes of tissue culture vessels (T25 to T75 to T225) prior to plating in 384-well format. The three cultures were initiated on consecutive days and subject to uniform handling procedures to ensure that dosing and sample collection also occurred on consecutive days. All chemical screening experiments were performed on P7 cells.

extract_protocol:
Six hours after chemical treatment, HTTr assay plates were removed from the incubator and media in each assay well was drained to a residual volume of 10 µL using MultiFlo FX microdispenser equipped with a vacuum-driven aspiration manifold. To create cell lysates, 10 µL volumes of 2X BioSpyder lysis buffer were dispensed into each assay well using the same MultiFlo FX instrument equipped with 1 µL peristaltic pump dispensing cassette. Then, 20 µL volumes of UHRR, HBRR, BLDSMO, BLTSA and Lysis Buffer reference material were manually dispensed into duplicate wells of column 1 of each assay plate. The plates were sealed with an adhesive aluminum plate cover and incubated at room temperature, protected from light, for 30 minutes. The plates were then stored at -80°C prior to shipment to BioSpyder, Inc.
Samples were analyzed by BioSpyder using a custom-attenuated version of the TempO-Seq human whole transcriptome version 1 (hWTv1) assay, which includes 21,111 probes covering 19,287 genes. Lysates were processed as described in (House et al. 2017). In brief, 2 µL of each lysate was hybridized with 2 µL of detector oligos from the hWTv1 assay using the following thermal cycler protocol: 10 min at 70°C, followed by gradual decrease to 45°C over 49 min, terminating with 45°C incubation for 16-24 hours. Excess oligos were then removed via nuclease digestion (90 min at 37°C) and hybridized detector oligos were ligated (60 min at 37°) following respective additions of 24 µL TempO-Seq nuclease and ligation mixes. RNA/DNA duplexes were then heat-denatured and 10 µL of each ligation product was transferred to an amplification microplate containing 10 µL of PCR master mix per well. Ligation products were then uniquely labeled during product amplification (10 min at 37°C, 2 min at 95°C, 6 cycles of 95°C for 30 s, 54°C for 30 s, 72°C for 120 s, 16 cycles of 95°C for 30s and 72°C for 120s, followed by 72°C for 60 s) with well coordinate-specific “barcoded” primer pairs containing universal adaptors for sequencing. Samples were then pooled into a series of three sequencing libraries (1 for each plate). Pooled sequencing libraries were then distributed across multiple lanes of a HiSeq dual flow cell and analyzed on a HiSeq 2500 Ultra-High-Throughput Sequencing System (Illumina, San Diego, CA).

treatment_protocol: DMSO-solubilized chemical stock solutions were received frozen from the US EPA ToxCast chemical inventory management contractor (EvoTec, Princeton, NJ) and stored at -80°C prior to dose plate preparation. An eight-point dilution series (1/2 log10 spacing) of test chemicals was prepared in a LabCyte Echo-qualified 384-well polypropylene (384PP) plate at 200x the desired nominal test concentration for screening (0.03 – 100 µM). Singleton wells of dosing solutions for each test chemical concentration were arrayed in columns 2 through 23 of the dose plate (Figure 1A). Transcriptomics reference chemicals (genistein, trichostatin A, sirolimus) were solubilized as 200x dosing solutions corresponding to nominal test concentrations of 10, 1 and 0.1 µM, respectively. Triplicate wells of dosing solutions for each of the transcriptomic reference chemicals were added to the dose plate (column 24) along with quadruplicate wells of pure DMSO as a vehicle control. At 24 h post-plating, 200 nL of 200x dosing solutions were transferred to the assay plates using a LabCyte Echo 550 acoustic dispenser. The final concentration of DMSO in all treatment, reference treatment and vehicle control wells was 0.5%.  Well coordinates on each assay plate were uniquely randomized with respect to treatment so that any potential edge-well effects were distributed in an unbiased manner across all possible treatment conditions.

tag: cell line

tag: media

value: DMEM + 10% HI-FBS

tag: treatment

value: 6h exposure of 3 uM of Vinclozolin

tag: chemical name

value: Vinclozolin

tag: chemical sample id

tag: chemical concentration

value: 3 uM

tag: dose level

tag: exposure time

tag: assay plate

tag: assay plate well


title: TP0001651C02_2_0.100000uM_DMEM_6h_TC00283171_B05

description:
TP0001651C02_2_0.100000uM_DMEM_6h
TC00283171_B05

value: 6h exposure of 0.1 uM of 4-Hydroxytamoxifen


title: TP0001651G02_6_10.000000uM_DMEM_6h_TC00283171_B12

description:
TP0001651G02_6_10.000000uM_DMEM_6h
TC00283171_B12

value: 6h exposure of 10 uM of Lovastatin

value: Lovastatin

value: 10 uM


title: TP0001651D04_8_100.000000uM_DMEM_6h_TC00283171_B11

description:
TP0001651D04_8_100.000000uM_DMEM_6h
TC00283171_B11

value: 6h exposure of 100 uM of Clofibrate

value: Clofibrate


title: TP0001651C06_5_3.000000uM_DMEM_6h_TC00283171_B06

description:
TP0001651C06_5_3.000000uM_DMEM_6h
TC00283171_B06

value: 6h exposure of 3 uM of Cycloheximide

value: Cycloheximide


title: TP0001651G02_8_100.000000uM_DMEM_6h_TC00283171_B07

description:
TP0001651G02_8_100.000000uM_DMEM_6h
TC00283171_B07

value: 6h exposure of 100 uM of Lovastatin


title: UHRR_TC00283171_B01

description:
UHRR
TC00283171_B01

source_name: Universal Human Reference RNA

tag: sample type

value: UHRR

value: untreated


title: TP0001651B05_3_0.300000uM_DMEM_6h_TC00283171_B09

description:
TP0001651B05_3_0.300000uM_DMEM_6h
TC00283171_B09

value: 6h exposure of 0.3 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651F04_7_30.000000uM_DMEM_6h_TC00283171_B02

description:
TP0001651F04_7_30.000000uM_DMEM_6h
TC00283171_B02

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Fulvestrant

value: Fulvestrant

value: 30 uM


title: TP0001651G03_6_10.000000uM_DMEM_6h_TC00283171_B08

description:
TP0001651G03_6_10.000000uM_DMEM_6h
TC00283171_B08

value: 6h exposure of 10 uM of Nilutamide

value: Nilutamide


title: TP0001651E03_2_0.100000uM_DMEM_6h_TC00283171_B04

description:
TP0001651E03_2_0.100000uM_DMEM_6h
TC00283171_B04

value: 6h exposure of 0.1 uM of Prochloraz

value: Prochloraz


title: TP0001651D01_1_0.030000uM_DMEM_6h_TC00283171_C02

description:
TP0001651D01_1_0.030000uM_DMEM_6h
TC00283171_C02

value: 6h exposure of 0.03 uM of Lactofen

value: Lactofen


title: TP0001651E05_7_30.000000uM_DMEM_6h_TC00283171_A23

description:
TP0001651E05_7_30.000000uM_DMEM_6h
TC00283171_A23

value: 6h exposure of 30 uM of Atrazine

value: Atrazine


title: TP0001651D01_7_30.000000uM_DMEM_6h_TC00283171_A22

description:
TP0001651D01_7_30.000000uM_DMEM_6h
TC00283171_A22

value: 6h exposure of 30 uM of Lactofen


title: TSA_DMEM_6h_TC00283171_A19

description:
TSA_DMEM_6h
TC00283171_A19

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A

value: 1 uM


title: TP0001651D05_2_0.100000uM_DMEM_6h_TC00283171_B03

description:
TP0001651D05_2_0.100000uM_DMEM_6h
TC00283171_B03

value: 6h exposure of 0.1 uM of Thiram

value: Thiram


title: Untrtd_DMEM_6h_TC00283171_A14

description:
Untrtd_DMEM_6h
TC00283171_A14

value: DMEM + 10% HI-FBS

value: untreated


title: TP0001651C04_7_30.000000uM_DMEM_6h_TC00283171_A24

description:
TP0001651C04_7_30.000000uM_DMEM_6h
TC00283171_A24

value: 6h exposure of 30 uM of Simvastatin

value: Simvastatin

value: 30 uM


title: DMSO_DMEM_6h_TC00283171_A16

description:
DMSO_DMEM_6h
TC00283171_A16

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651D02_5_3.000000uM_DMEM_6h_TC00283171_A10

description:
TP0001651D02_5_3.000000uM_DMEM_6h
TC00283171_A10

value: 6h exposure of 3 uM of PFOA

value: PFOA

value: 3 uM


title: TP0001651G03_8_100.000000uM_DMEM_6h_TC00283171_A21

description:
TP0001651G03_8_100.000000uM_DMEM_6h
TC00283171_A21

value: 6h exposure of 100 uM of Nilutamide

value: Nilutamide


title: TP0001651C01_8_100.000000uM_DMEM_6h_TC00283171_A11

description:
TP0001651C01_8_100.000000uM_DMEM_6h
TC00283171_A11

value: 6h exposure of 100 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651B06_5_3.000000uM_DMEM_6h_TC00283171_A20

description:
TP0001651B06_5_3.000000uM_DMEM_6h
TC00283171_A20

value: 6h exposure of 3 uM of Troglitazone

value: Troglitazone


title: TP0001651E03_7_30.000000uM_DMEM_6h_TC00283171_A18

description:
TP0001651E03_7_30.000000uM_DMEM_6h
TC00283171_A18

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Prochloraz

value: Prochloraz


title: TP0001651C04_6_10.000000uM_DMEM_6h_TC00283171_A17

description:
TP0001651C04_6_10.000000uM_DMEM_6h
TC00283171_A17

value: 6h exposure of 10 uM of Simvastatin

value: Simvastatin

value: 10 uM


title: TP0001651G03_2_0.100000uM_DMEM_6h_TC00283171_A08

description:
TP0001651G03_2_0.100000uM_DMEM_6h
TC00283171_A08

value: 6h exposure of 0.1 uM of Nilutamide


title: TP0001651E05_2_0.100000uM_DMEM_6h_TC00283171_A15

description:
TP0001651E05_2_0.100000uM_DMEM_6h
TC00283171_A15

value: 6h exposure of 0.1 uM of Atrazine

value: Atrazine


title: TP0001651H01_5_3.000000uM_DMEM_6h_TC00283171_A13

description:
TP0001651H01_5_3.000000uM_DMEM_6h
TC00283171_A13

value: 6h exposure of 3 uM of Flutamide

value: Flutamide


title: UHRR_TC00283171_A01

description:
UHRR
TC00283171_A01

value: UHRR

value: untreated


title: TP0001651E04_4_1.000000uM_DMEM_6h_TC00283151_P23

description:
TP0001651E04_4_1.000000uM_DMEM_6h
TC00283151_P23

value: 6h exposure of 1 uM of Farglitazar

value: Farglitazar

value: 1 uM


title: SIRO_DMEM_6h_TC00283151_P21

description:
SIRO_DMEM_6h
TC00283151_P21

value: 6h exposure of 0.1 uM of Sirolimus

value: Sirolimus


title: TP0001651B02_2_0.100000uM_DMEM_6h_TC00283171_A12

description:
TP0001651B02_2_0.100000uM_DMEM_6h
TC00283171_A12

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of 3,5,3'-Triiodothyronine


title: TP0001651C01_6_10.000000uM_DMEM_6h_TC00283151_P17

description:
TP0001651C01_6_10.000000uM_DMEM_6h
TC00283151_P17

value: 6h exposure of 10 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651D03_2_0.100000uM_DMEM_6h_TC00283171_A09

description:
TP0001651D03_2_0.100000uM_DMEM_6h
TC00283171_A09

value: 6h exposure of 0.1 uM of Cypermethrin

value: Cypermethrin


title: TP0001651E03_5_3.000000uM_DMEM_6h_TC00283171_A05

description:
TP0001651E03_5_3.000000uM_DMEM_6h
TC00283171_A05

value: 6h exposure of 3 uM of Prochloraz

value: Prochloraz

value: 3 uM


title: TP0001651B01_1_0.030000uM_DMEM_6h_TC00283171_A07

description:
TP0001651B01_1_0.030000uM_DMEM_6h
TC00283171_A07

value: 6h exposure of 0.03 uM of Cyanazine

value: Cyanazine


title: TP0001651A02_2_0.100000uM_DMEM_6h_TC00283171_A04

description:
TP0001651A02_2_0.100000uM_DMEM_6h
TC00283171_A04

value: 6h exposure of 0.1 uM of Imazalil

value: Imazalil


title: TP0001651G04_2_0.100000uM_DMEM_6h_TC00283151_P24

description:
TP0001651G04_2_0.100000uM_DMEM_6h
TC00283151_P24

value: 6h exposure of 0.1 uM of Cladribine

value: Cladribine


title: TP0001651F01_4_1.000000uM_DMEM_6h_TC00283171_A03

description:
TP0001651F01_4_1.000000uM_DMEM_6h
TC00283171_A03

value: 6h exposure of 1 uM of Tetrac

value: Tetrac

value: 1 uM


title: TP0001651F04_8_100.000000uM_DMEM_6h_TC00283151_P22

description:
TP0001651F04_8_100.000000uM_DMEM_6h
TC00283151_P22

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Fulvestrant

value: Fulvestrant


title: TP0001651A03_3_0.300000uM_DMEM_6h_TC00283151_P20

description:
TP0001651A03_3_0.300000uM_DMEM_6h
TC00283151_P20

value: 6h exposure of 0.3 uM of Butafenacil

value: Butafenacil


title: TP0001651F05_5_3.000000uM_DMEM_6h_TC00283151_P13

description:
TP0001651F05_5_3.000000uM_DMEM_6h
TC00283151_P13

value: 6h exposure of 3 uM of Fenofibrate

value: Fenofibrate


title: TP0001651A02_6_10.000000uM_DMEM_6h_TC00283151_P18

description:
TP0001651A02_6_10.000000uM_DMEM_6h
TC00283151_P18

value: 6h exposure of 10 uM of Imazalil

value: 10 uM


title: TP0001651G05_6_10.000000uM_DMEM_6h_TC00283151_P10

description:
TP0001651G05_6_10.000000uM_DMEM_6h
TC00283151_P10

value: 6h exposure of 10 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651E04_6_10.000000uM_DMEM_6h_TC00283151_P08

description:
TP0001651E04_6_10.000000uM_DMEM_6h
TC00283151_P08

value: 6h exposure of 10 uM of Farglitazar

value: Farglitazar


title: TP0001651D04_1_0.030000uM_DMEM_6h_TC00283151_P14

description:
TP0001651D04_1_0.030000uM_DMEM_6h
TC00283151_P14

value: 6h exposure of 0.03 uM of Clofibrate

value: Clofibrate


title: TP0001651E02_1_0.030000uM_DMEM_6h_TC00283171_A06

description:
TP0001651E02_1_0.030000uM_DMEM_6h
TC00283171_A06

value: 6h exposure of 0.03 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651E01_6_10.000000uM_DMEM_6h_TC00283151_P07

description:
TP0001651E01_6_10.000000uM_DMEM_6h
TC00283151_P07

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Bifenthrin

value: Bifenthrin


title: TP0001651E02_4_1.000000uM_DMEM_6h_TC00283151_P15

description:
TP0001651E02_4_1.000000uM_DMEM_6h
TC00283151_P15

value: 6h exposure of 1 uM of 4-Nonylphenol, branched

value: 1 uM


title: TP0001651G04_7_30.000000uM_DMEM_6h_TC00283151_P16

description:
TP0001651G04_7_30.000000uM_DMEM_6h
TC00283151_P16

value: 6h exposure of 30 uM of Cladribine

value: Cladribine

value: 30 uM


title: TP0001651F01_2_0.100000uM_DMEM_6h_TC00283151_P06

description:
TP0001651F01_2_0.100000uM_DMEM_6h
TC00283151_P06

value: 6h exposure of 0.1 uM of Tetrac

value: Tetrac


title: TP0001651A05_5_3.000000uM_DMEM_6h_TC00283151_P11

description:
TP0001651A05_5_3.000000uM_DMEM_6h
TC00283151_P11

value: 6h exposure of 3 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)

value: 3 uM


title: TP0001651G05_8_100.000000uM_DMEM_6h_TC00283151_P09

description:
TP0001651G05_8_100.000000uM_DMEM_6h
TC00283151_P09

value: 6h exposure of 100 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651A01_8_100.000000uM_DMEM_6h_TC00283171_A02

description:
TP0001651A01_8_100.000000uM_DMEM_6h
TC00283171_A02

value: 6h exposure of 100 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651H01_4_1.000000uM_DMEM_6h_TC00283151_P12

description:
TP0001651H01_4_1.000000uM_DMEM_6h
TC00283151_P12

value: DMEM + 10% HI-FBS

value: 6h exposure of 1 uM of Flutamide

value: Flutamide


title: TP0001651B04_1_0.030000uM_DMEM_6h_TC00283151_P05

description:
TP0001651B04_1_0.030000uM_DMEM_6h
TC00283151_P05

value: 6h exposure of 0.03 uM of Propiconazole

value: Propiconazole


title: TP0001651E04_8_100.000000uM_DMEM_6h_TC00283151_P03

description:
TP0001651E04_8_100.000000uM_DMEM_6h
TC00283151_P03

value: 6h exposure of 100 uM of Farglitazar

value: Farglitazar


title: TP0001651E04_3_0.300000uM_DMEM_6h_TC00283151_P04

description:
TP0001651E04_3_0.300000uM_DMEM_6h
TC00283151_P04

value: 6h exposure of 0.3 uM of Farglitazar


title: TP0001651A01_4_1.000000uM_DMEM_6h_TC00283151_P02

description:
TP0001651A01_4_1.000000uM_DMEM_6h
TC00283151_P02

value: 6h exposure of 1 uM of Pyraclostrobin

value: 1 uM


title: TP0001651A01_8_100.000000uM_DMEM_6h_TC00283151_O24

description:
TP0001651A01_8_100.000000uM_DMEM_6h
TC00283151_O24


title: TP0001651G02_7_30.000000uM_DMEM_6h_TC00283151_O22

description:
TP0001651G02_7_30.000000uM_DMEM_6h
TC00283151_O22

value: 6h exposure of 30 uM of Lovastatin

value: Lovastatin

value: 30 uM


title: TP0001651E05_8_100.000000uM_DMEM_6h_TC00283151_O21

description:
TP0001651E05_8_100.000000uM_DMEM_6h
TC00283151_O21

value: 6h exposure of 100 uM of Atrazine

value: Atrazine


title: TP0001651H01_6_10.000000uM_DMEM_6h_TC00283151_O20

description:
TP0001651H01_6_10.000000uM_DMEM_6h
TC00283151_O20

value: 6h exposure of 10 uM of Flutamide

value: 10 uM


title: TP0001651H04_3_0.300000uM_DMEM_6h_TC00283151_O23

description:
TP0001651H04_3_0.300000uM_DMEM_6h
TC00283151_O23

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.3 uM of Bisphenol A

value: Bisphenol A


title: TP0001651A04_6_10.000000uM_DMEM_6h_TC00283151_O19

description:
TP0001651A04_6_10.000000uM_DMEM_6h
TC00283151_O19

value: 6h exposure of 10 uM of Rotenone

value: Rotenone


title: TP0001651C06_3_0.300000uM_DMEM_6h_TC00283151_O16

description:
TP0001651C06_3_0.300000uM_DMEM_6h
TC00283151_O16

value: 6h exposure of 0.3 uM of Cycloheximide

value: Cycloheximide


title: TP0001651C01_4_1.000000uM_DMEM_6h_TC00283151_O17

description:
TP0001651C01_4_1.000000uM_DMEM_6h
TC00283151_O17

value: 6h exposure of 1 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651C06_1_0.030000uM_DMEM_6h_TC00283151_O15

description:
TP0001651C06_1_0.030000uM_DMEM_6h
TC00283151_O15

value: 6h exposure of 0.03 uM of Cycloheximide


title: TP0001651E01_3_0.300000uM_DMEM_6h_TC00283151_O13

description:
TP0001651E01_3_0.300000uM_DMEM_6h
TC00283151_O13

value: 6h exposure of 0.3 uM of Bifenthrin

value: Bifenthrin


title: TP0001651F04_5_3.000000uM_DMEM_6h_TC00283151_O12

description:
TP0001651F04_5_3.000000uM_DMEM_6h
TC00283151_O12

value: 6h exposure of 3 uM of Fulvestrant

value: Fulvestrant

value: 3 uM


title: TP0001651F03_1_0.030000uM_DMEM_6h_TC00283151_O10

description:
TP0001651F03_1_0.030000uM_DMEM_6h
TC00283151_O10

value: 6h exposure of 0.03 uM of 4-Cumylphenol


title: TP0001651H04_4_1.000000uM_DMEM_6h_TC00283151_O09

description:
TP0001651H04_4_1.000000uM_DMEM_6h
TC00283151_O09

value: 6h exposure of 1 uM of Bisphenol A

value: 1 uM


title: TP0001651E04_7_30.000000uM_DMEM_6h_TC00283151_O14

description:
TP0001651E04_7_30.000000uM_DMEM_6h
TC00283151_O14

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Farglitazar

value: Farglitazar

value: 30 uM


title: TP0001651B04_6_10.000000uM_DMEM_6h_TC00283151_O08

description:
TP0001651B04_6_10.000000uM_DMEM_6h
TC00283151_O08

value: 6h exposure of 10 uM of Propiconazole

value: Propiconazole

value: 10 uM


title: TP0001651A05_2_0.100000uM_DMEM_6h_TC00283151_O11

description:
TP0001651A05_2_0.100000uM_DMEM_6h
TC00283151_O11

value: 6h exposure of 0.1 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651H02_7_30.000000uM_DMEM_6h_TC00283151_O07

description:
TP0001651H02_7_30.000000uM_DMEM_6h
TC00283151_O07

value: 6h exposure of 30 uM of Maneb

value: Maneb


title: TP0001651H02_5_3.000000uM_DMEM_6h_TC00283151_O04

description:
TP0001651H02_5_3.000000uM_DMEM_6h
TC00283151_O04

value: 6h exposure of 3 uM of Maneb


title: TP0001651A05_7_30.000000uM_DMEM_6h_TC00283151_O05

description:
TP0001651A05_7_30.000000uM_DMEM_6h
TC00283151_O05

value: 6h exposure of 30 uM of Clomiphene citrate (1:1)


title: TP0001651G03_3_0.300000uM_DMEM_6h_TC00283151_N24

description:
TP0001651G03_3_0.300000uM_DMEM_6h
TC00283151_N24

value: 6h exposure of 0.3 uM of Nilutamide

value: Nilutamide


title: TP0001651G02_1_0.030000uM_DMEM_6h_TC00283151_O06

description:
TP0001651G02_1_0.030000uM_DMEM_6h
TC00283151_O06

value: 6h exposure of 0.03 uM of Lovastatin

value: Lovastatin


title: TP0001651G01_5_3.000000uM_DMEM_6h_TC00283151_N23

description:
TP0001651G01_5_3.000000uM_DMEM_6h
TC00283151_N23

value: DMEM + 10% HI-FBS

value: 6h exposure of 3 uM of Vinclozolin

value: Vinclozolin

value: 3 uM


title: TP0001651C01_3_0.300000uM_DMEM_6h_TC00283151_O03

description:
TP0001651C01_3_0.300000uM_DMEM_6h
TC00283151_O03

value: 6h exposure of 0.3 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651G03_2_0.100000uM_DMEM_6h_TC00283151_O02

description:
TP0001651G03_2_0.100000uM_DMEM_6h
TC00283151_O02

value: 6h exposure of 0.1 uM of Nilutamide


title: TP0001651D04_8_100.000000uM_DMEM_6h_TC00283151_N20

description:
TP0001651D04_8_100.000000uM_DMEM_6h
TC00283151_N20

value: 6h exposure of 100 uM of Clofibrate

value: Clofibrate


title: TP0001651C01_5_3.000000uM_DMEM_6h_TC00283151_N21

description:
TP0001651C01_5_3.000000uM_DMEM_6h
TC00283151_N21

value: 6h exposure of 3 uM of Fenpyroximate (Z,E)


title: TP0001651E01_1_0.030000uM_DMEM_6h_TC00283151_N22

description:
TP0001651E01_1_0.030000uM_DMEM_6h
TC00283151_N22

value: 6h exposure of 0.03 uM of Bifenthrin

value: Bifenthrin


title: TP0001651A02_3_0.300000uM_DMEM_6h_TC00283151_N19

description:
TP0001651A02_3_0.300000uM_DMEM_6h
TC00283151_N19

value: 6h exposure of 0.3 uM of Imazalil

value: Imazalil


title: TP0001651B03_3_0.300000uM_DMEM_6h_TC00283151_P19

description:
TP0001651B03_3_0.300000uM_DMEM_6h
TC00283151_P19

value: 6h exposure of 0.3 uM of Reserpine

value: Reserpine


title: TP0001651B06_5_3.000000uM_DMEM_6h_TC00283151_O18

description:
TP0001651B06_5_3.000000uM_DMEM_6h
TC00283151_O18

value: 6h exposure of 3 uM of Troglitazone

value: Troglitazone


title: TP0001651B02_5_3.000000uM_DMEM_6h_TC00283151_N17

description:
TP0001651B02_5_3.000000uM_DMEM_6h
TC00283151_N17

value: DMEM + 10% HI-FBS

value: 6h exposure of 3 uM of 3,5,3'-Triiodothyronine


title: TP0001651B03_1_0.030000uM_DMEM_6h_TC00283151_N15

description:
TP0001651B03_1_0.030000uM_DMEM_6h
TC00283151_N15

value: 6h exposure of 0.03 uM of Reserpine


title: TP0001651F04_4_1.000000uM_DMEM_6h_TC00283151_N18

description:
TP0001651F04_4_1.000000uM_DMEM_6h
TC00283151_N18

value: 6h exposure of 1 uM of Fulvestrant

value: Fulvestrant

value: 1 uM


title: Untrtd_DMEM_6h_TC00283151_N14

description:
Untrtd_DMEM_6h
TC00283151_N14

value: untreated


title: TP0001651A02_7_30.000000uM_DMEM_6h_TC00283151_N16

description:
TP0001651A02_7_30.000000uM_DMEM_6h
TC00283151_N16

value: 6h exposure of 30 uM of Imazalil

value: 30 uM


title: TSA_DMEM_6h_TC00283151_N13

description:
TSA_DMEM_6h
TC00283151_N13

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A


title: TP0001651H05_7_30.000000uM_DMEM_6h_TC00283151_N11

description:
TP0001651H05_7_30.000000uM_DMEM_6h
TC00283151_N11

value: 6h exposure of 30 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651D03_3_0.300000uM_DMEM_6h_TC00283151_N10

description:
TP0001651D03_3_0.300000uM_DMEM_6h
TC00283151_N10

value: 6h exposure of 0.3 uM of Cypermethrin

value: Cypermethrin


title: TP0001651H02_3_0.300000uM_DMEM_6h_TC00283151_N09

description:
TP0001651H02_3_0.300000uM_DMEM_6h
TC00283151_N09

value: 6h exposure of 0.3 uM of Maneb

value: Maneb


title: TP0001651A04_7_30.000000uM_DMEM_6h_TC00283151_N08

description:
TP0001651A04_7_30.000000uM_DMEM_6h
TC00283151_N08

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Rotenone

value: Rotenone


title: TP0001651F03_7_30.000000uM_DMEM_6h_TC00283151_N06

description:
TP0001651F03_7_30.000000uM_DMEM_6h
TC00283151_N06

value: 6h exposure of 30 uM of 4-Cumylphenol


title: TP0001651A03_4_1.000000uM_DMEM_6h_TC00283151_N05

description:
TP0001651A03_4_1.000000uM_DMEM_6h
TC00283151_N05

value: 6h exposure of 1 uM of Butafenacil

value: Butafenacil


title: TP0001651F05_2_0.100000uM_DMEM_6h_TC00283151_N03

description:
TP0001651F05_2_0.100000uM_DMEM_6h
TC00283151_N03

value: 6h exposure of 0.1 uM of Fenofibrate

value: Fenofibrate


title: TP0001651D02_8_100.000000uM_DMEM_6h_TC00283151_N04

description:
TP0001651D02_8_100.000000uM_DMEM_6h
TC00283151_N04

value: 6h exposure of 100 uM of PFOA

value: PFOA


title: SIRO_DMEM_6h_TC00283151_N02

description:
SIRO_DMEM_6h
TC00283151_N02

value: 6h exposure of 0.1 uM of Sirolimus

value: Sirolimus


title: TP0001651A01_5_3.000000uM_DMEM_6h_TC00283151_N07

description:
TP0001651A01_5_3.000000uM_DMEM_6h
TC00283151_N07

value: 6h exposure of 3 uM of Pyraclostrobin

value: Pyraclostrobin

value: 3 uM


title: TP0001651A03_6_10.000000uM_DMEM_6h_TC00283151_M23

description:
TP0001651A03_6_10.000000uM_DMEM_6h
TC00283151_M23

value: 6h exposure of 10 uM of Butafenacil

value: 10 uM


title: TP0001651A02_1_0.030000uM_DMEM_6h_TC00283151_M22

description:
TP0001651A02_1_0.030000uM_DMEM_6h
TC00283151_M22

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.03 uM of Imazalil

value: Imazalil


title: TP0001651F01_6_10.000000uM_DMEM_6h_TC00283151_M19

description:
TP0001651F01_6_10.000000uM_DMEM_6h
TC00283151_M19

value: 6h exposure of 10 uM of Tetrac

value: Tetrac


title: TP0001651D01_5_3.000000uM_DMEM_6h_TC00283151_M17

description:
TP0001651D01_5_3.000000uM_DMEM_6h
TC00283151_M17

value: 6h exposure of 3 uM of Lactofen

value: Lactofen


title: TP0001651C02_6_10.000000uM_DMEM_6h_TC00283151_M15

description:
TP0001651C02_6_10.000000uM_DMEM_6h
TC00283151_M15

value: 6h exposure of 10 uM of 4-Hydroxytamoxifen


title: TP0001651H04_8_100.000000uM_DMEM_6h_TC00283151_M16

description:
TP0001651H04_8_100.000000uM_DMEM_6h
TC00283151_M16

value: 6h exposure of 100 uM of Bisphenol A

value: Bisphenol A


title: TP0001651H02_4_1.000000uM_DMEM_6h_TC00283151_M20

description:
TP0001651H02_4_1.000000uM_DMEM_6h
TC00283151_M20

value: 6h exposure of 1 uM of Maneb

value: Maneb

value: 1 uM


title: TP0001651H03_6_10.000000uM_DMEM_6h_TC00283151_M13

description:
TP0001651H03_6_10.000000uM_DMEM_6h
TC00283151_M13

value: 6h exposure of 10 uM of Fomesafen

value: Fomesafen


title: TP0001651B04_2_0.100000uM_DMEM_6h_TC00283151_M12

description:
TP0001651B04_2_0.100000uM_DMEM_6h
TC00283151_M12

value: 6h exposure of 0.1 uM of Propiconazole

value: Propiconazole


title: TP0001651E03_3_0.300000uM_DMEM_6h_TC00283151_M11

description:
TP0001651E03_3_0.300000uM_DMEM_6h
TC00283151_M11

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.3 uM of Prochloraz

value: Prochloraz


title: TP0001651C02_3_0.300000uM_DMEM_6h_TC00283151_M21

description:
TP0001651C02_3_0.300000uM_DMEM_6h
TC00283151_M21

value: 6h exposure of 0.3 uM of 4-Hydroxytamoxifen


title: TP0001651B03_5_3.000000uM_DMEM_6h_TC00283151_M10

description:
TP0001651B03_5_3.000000uM_DMEM_6h
TC00283151_M10

value: 6h exposure of 3 uM of Reserpine

value: Reserpine

value: 3 uM


title: TP0001651B04_4_1.000000uM_DMEM_6h_TC00283151_M09

description:
TP0001651B04_4_1.000000uM_DMEM_6h
TC00283151_M09

value: 6h exposure of 1 uM of Propiconazole


title: TP0001651F02_4_1.000000uM_DMEM_6h_TC00283151_M08

description:
TP0001651F02_4_1.000000uM_DMEM_6h
TC00283151_M08

value: 6h exposure of 1 uM of Ziram

value: Ziram


title: TP0001651H01_3_0.300000uM_DMEM_6h_TC00283151_M06

description:
TP0001651H01_3_0.300000uM_DMEM_6h
TC00283151_M06

value: 6h exposure of 0.3 uM of Flutamide

value: Flutamide


title: TSA_DMEM_6h_TC00283151_M07

description:
TSA_DMEM_6h
TC00283151_M07

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A

value: 1 uM


title: TP0001651A03_5_3.000000uM_DMEM_6h_TC00283151_N12

description:
TP0001651A03_5_3.000000uM_DMEM_6h
TC00283151_N12

value: 6h exposure of 3 uM of Butafenacil

value: Butafenacil


title: TP0001651E01_2_0.100000uM_DMEM_6h_TC00283151_M03

description:
TP0001651E01_2_0.100000uM_DMEM_6h
TC00283151_M03

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of Bifenthrin

value: Bifenthrin


title: TP0001651B03_2_0.100000uM_DMEM_6h_TC00283151_M14

description:
TP0001651B03_2_0.100000uM_DMEM_6h
TC00283151_M14

value: 6h exposure of 0.1 uM of Reserpine


title: TP0001651A03_1_0.030000uM_DMEM_6h_TC00283151_M05

description:
TP0001651A03_1_0.030000uM_DMEM_6h
TC00283151_M05

value: 6h exposure of 0.03 uM of Butafenacil


title: TP0001651C05_3_0.300000uM_DMEM_6h_TC00283151_M24

description:
TP0001651C05_3_0.300000uM_DMEM_6h
TC00283151_M24

value: 6h exposure of 0.3 uM of Bisphenol B

value: Bisphenol B


title: TP0001651D04_6_10.000000uM_DMEM_6h_TC00283151_L22

description:
TP0001651D04_6_10.000000uM_DMEM_6h
TC00283151_L22

value: 6h exposure of 10 uM of Clofibrate

value: Clofibrate

value: 10 uM


title: TP0001651C05_7_30.000000uM_DMEM_6h_TC00283151_L24

description:
TP0001651C05_7_30.000000uM_DMEM_6h
TC00283151_L24

value: 6h exposure of 30 uM of Bisphenol B

value: 30 uM


title: TP0001651A05_6_10.000000uM_DMEM_6h_TC00283151_L23

description:
TP0001651A05_6_10.000000uM_DMEM_6h
TC00283151_L23

value: 6h exposure of 10 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651A04_5_3.000000uM_DMEM_6h_TC00283151_L21

description:
TP0001651A04_5_3.000000uM_DMEM_6h
TC00283151_L21

value: 6h exposure of 3 uM of Rotenone

value: Rotenone

value: 3 uM


title: TP0001651A06_7_30.000000uM_DMEM_6h_TC00283151_L20

description:
TP0001651A06_7_30.000000uM_DMEM_6h
TC00283151_L20

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Cyproconazole

value: Cyproconazole


title: TP0001651D05_5_3.000000uM_DMEM_6h_TC00283151_L19

description:
TP0001651D05_5_3.000000uM_DMEM_6h
TC00283151_L19

value: 6h exposure of 3 uM of Thiram

value: Thiram


title: TP0001651C03_4_1.000000uM_DMEM_6h_TC00283151_L18

description:
TP0001651C03_4_1.000000uM_DMEM_6h
TC00283151_L18

value: 6h exposure of 1 uM of Simazine

value: Simazine

value: 1 uM


title: TP0001651F04_2_0.100000uM_DMEM_6h_TC00283151_L17

description:
TP0001651F04_2_0.100000uM_DMEM_6h
TC00283151_L17

value: 6h exposure of 0.1 uM of Fulvestrant

value: Fulvestrant


title: TP0001651A01_7_30.000000uM_DMEM_6h_TC00283151_M18

description:
TP0001651A01_7_30.000000uM_DMEM_6h
TC00283151_M18

value: 6h exposure of 30 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651F02_7_30.000000uM_DMEM_6h_TC00283151_L16

description:
TP0001651F02_7_30.000000uM_DMEM_6h
TC00283151_L16

value: 6h exposure of 30 uM of Ziram

value: Ziram

value: 30 uM


title: TP0001651F02_8_100.000000uM_DMEM_6h_TC00283151_L14

description:
TP0001651F02_8_100.000000uM_DMEM_6h
TC00283151_L14

value: 6h exposure of 100 uM of Ziram


title: TP0001651A04_4_1.000000uM_DMEM_6h_TC00283151_L13

description:
TP0001651A04_4_1.000000uM_DMEM_6h
TC00283151_L13

value: 6h exposure of 1 uM of Rotenone

value: Rotenone


title: TP0001651E01_7_30.000000uM_DMEM_6h_TC00283151_L12

description:
TP0001651E01_7_30.000000uM_DMEM_6h
TC00283151_L12

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Bifenthrin

value: Bifenthrin


title: TP0001651C04_6_10.000000uM_DMEM_6h_TC00283151_L05

description:
TP0001651C04_6_10.000000uM_DMEM_6h
TC00283151_L05

value: 6h exposure of 10 uM of Simvastatin

value: Simvastatin

value: 10 uM


title: TP0001651H01_5_3.000000uM_DMEM_6h_TC00283151_K24

description:
TP0001651H01_5_3.000000uM_DMEM_6h
TC00283151_K24

value: 6h exposure of 3 uM of Flutamide

value: Flutamide

value: 3 uM


title: TP0001651G04_6_10.000000uM_DMEM_6h_TC00283151_L03

description:
TP0001651G04_6_10.000000uM_DMEM_6h
TC00283151_L03

value: 6h exposure of 10 uM of Cladribine

value: Cladribine


title: TP0001651F03_3_0.300000uM_DMEM_6h_TC00283151_L09

description:
TP0001651F03_3_0.300000uM_DMEM_6h
TC00283151_L09

value: 6h exposure of 0.3 uM of 4-Cumylphenol


title: TP0001651D04_5_3.000000uM_DMEM_6h_TC00283151_M02

description:
TP0001651D04_5_3.000000uM_DMEM_6h
TC00283151_M02

value: 6h exposure of 3 uM of Clofibrate

value: Clofibrate


title: TP0001651C01_1_0.030000uM_DMEM_6h_TC00283151_L11

description:
TP0001651C01_1_0.030000uM_DMEM_6h
TC00283151_L11

value: 6h exposure of 0.03 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651F03_8_100.000000uM_DMEM_6h_TC00283151_K18

description:
TP0001651F03_8_100.000000uM_DMEM_6h
TC00283151_K18

value: 6h exposure of 100 uM of 4-Cumylphenol


title: TP0001651A04_3_0.300000uM_DMEM_6h_TC00283151_L10

description:
TP0001651A04_3_0.300000uM_DMEM_6h
TC00283151_L10

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.3 uM of Rotenone

value: Rotenone


title: TP0001651C05_5_3.000000uM_DMEM_6h_TC00283151_K21

description:
TP0001651C05_5_3.000000uM_DMEM_6h
TC00283151_K21

value: 6h exposure of 3 uM of Bisphenol B

value: Bisphenol B


title: TP0001651A06_5_3.000000uM_DMEM_6h_TC00283151_K15

description:
TP0001651A06_5_3.000000uM_DMEM_6h
TC00283151_K15

value: 6h exposure of 3 uM of Cyproconazole

value: Cyproconazole


title: TP0001651D01_4_1.000000uM_DMEM_6h_TC00283151_M04

description:
TP0001651D01_4_1.000000uM_DMEM_6h
TC00283151_M04

value: 6h exposure of 1 uM of Lactofen

value: Lactofen

value: 1 uM


title: TP0001651B06_7_30.000000uM_DMEM_6h_TC00283151_L07

description:
TP0001651B06_7_30.000000uM_DMEM_6h
TC00283151_L07

value: 6h exposure of 30 uM of Troglitazone

value: Troglitazone

value: 30 uM


title: TP0001651E03_2_0.100000uM_DMEM_6h_TC00283151_L02

description:
TP0001651E03_2_0.100000uM_DMEM_6h
TC00283151_L02

value: 6h exposure of 0.1 uM of Prochloraz

value: Prochloraz


title: TP0001651F02_1_0.030000uM_DMEM_6h_TC00283151_K14

description:
TP0001651F02_1_0.030000uM_DMEM_6h
TC00283151_K14

value: 6h exposure of 0.03 uM of Ziram

value: Ziram


title: TP0001651E02_5_3.000000uM_DMEM_6h_TC00283151_L04

description:
TP0001651E02_5_3.000000uM_DMEM_6h
TC00283151_L04

value: DMEM + 10% HI-FBS

value: 6h exposure of 3 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched

value: 3 uM


title: TP0001651B01_4_1.000000uM_DMEM_6h_TC00283151_K23

description:
TP0001651B01_4_1.000000uM_DMEM_6h
TC00283151_K23

value: 6h exposure of 1 uM of Cyanazine

value: Cyanazine


title: TP0001651C05_6_10.000000uM_DMEM_6h_TC00283151_L06

description:
TP0001651C05_6_10.000000uM_DMEM_6h
TC00283151_L06

value: 6h exposure of 10 uM of Bisphenol B

value: Bisphenol B

value: 10 uM


title: TP0001651D02_4_1.000000uM_DMEM_6h_TC00283151_K17

description:
TP0001651D02_4_1.000000uM_DMEM_6h
TC00283151_K17

value: 6h exposure of 1 uM of PFOA

value: PFOA

value: 1 uM


title: TP0001651B02_4_1.000000uM_DMEM_6h_TC00283151_K16

description:
TP0001651B02_4_1.000000uM_DMEM_6h
TC00283151_K16

value: 6h exposure of 1 uM of 3,5,3'-Triiodothyronine


title: TP0001651G04_8_100.000000uM_DMEM_6h_TC00283151_K09

description:
TP0001651G04_8_100.000000uM_DMEM_6h
TC00283151_K09

value: 6h exposure of 100 uM of Cladribine

value: Cladribine


title: TP0001651F03_6_10.000000uM_DMEM_6h_TC00283151_K12

description:
TP0001651F03_6_10.000000uM_DMEM_6h
TC00283151_K12

value: 6h exposure of 10 uM of 4-Cumylphenol


title: TP0001651G05_7_30.000000uM_DMEM_6h_TC00283151_K11

description:
TP0001651G05_7_30.000000uM_DMEM_6h
TC00283151_K11

value: 6h exposure of 30 uM of Cyproterone acetate

value: Cyproterone acetate

value: 30 uM


title: TP0001651D06_1_0.030000uM_DMEM_6h_TC00283151_L08

description:
TP0001651D06_1_0.030000uM_DMEM_6h
TC00283151_L08

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.03 uM of PFOS

value: PFOS


title: TP0001651C03_7_30.000000uM_DMEM_6h_TC00283151_K13

description:
TP0001651C03_7_30.000000uM_DMEM_6h
TC00283151_K13

value: 6h exposure of 30 uM of Simazine

value: Simazine


title: TP0001651C04_8_100.000000uM_DMEM_6h_TC00283151_K10

description:
TP0001651C04_8_100.000000uM_DMEM_6h
TC00283151_K10

value: 6h exposure of 100 uM of Simvastatin

value: Simvastatin


title: TP0001651E04_5_3.000000uM_DMEM_6h_TC00283151_L15

description:
TP0001651E04_5_3.000000uM_DMEM_6h
TC00283151_L15

value: 6h exposure of 3 uM of Farglitazar

value: Farglitazar

value: 3 uM


title: TP0001651G01_2_0.100000uM_DMEM_6h_TC00283151_K19

description:
TP0001651G01_2_0.100000uM_DMEM_6h
TC00283151_K19

value: 6h exposure of 0.1 uM of Vinclozolin

value: Vinclozolin


title: TP0001651E05_4_1.000000uM_DMEM_6h_TC00283151_K20

description:
TP0001651E05_4_1.000000uM_DMEM_6h
TC00283151_K20

value: 6h exposure of 1 uM of Atrazine

value: Atrazine

value: 1 uM


title: TP0001651B04_3_0.300000uM_DMEM_6h_TC00283151_K22

description:
TP0001651B04_3_0.300000uM_DMEM_6h
TC00283151_K22

value: 6h exposure of 0.3 uM of Propiconazole

value: Propiconazole


title: TP0001651C02_5_3.000000uM_DMEM_6h_TC00283151_K08

description:
TP0001651C02_5_3.000000uM_DMEM_6h
TC00283151_K08

value: DMEM + 10% HI-FBS

value: 6h exposure of 3 uM of 4-Hydroxytamoxifen


title: TP0001651H02_8_100.000000uM_DMEM_6h_TC00283151_K05

description:
TP0001651H02_8_100.000000uM_DMEM_6h
TC00283151_K05

value: 6h exposure of 100 uM of Maneb

value: Maneb


title: TP0001651G02_5_3.000000uM_DMEM_6h_TC00283151_K06

description:
TP0001651G02_5_3.000000uM_DMEM_6h
TC00283151_K06

value: 6h exposure of 3 uM of Lovastatin

value: Lovastatin


title: TP0001651E02_8_100.000000uM_DMEM_6h_TC00283151_J22

description:
TP0001651E02_8_100.000000uM_DMEM_6h
TC00283151_J22

value: 6h exposure of 100 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651H01_7_30.000000uM_DMEM_6h_TC00283151_K07

description:
TP0001651H01_7_30.000000uM_DMEM_6h
TC00283151_K07

value: 6h exposure of 30 uM of Flutamide

value: Flutamide

value: 30 uM


title: TP0001651D03_1_0.030000uM_DMEM_6h_TC00283151_K04

description:
TP0001651D03_1_0.030000uM_DMEM_6h
TC00283151_K04

value: 6h exposure of 0.03 uM of Cypermethrin

value: Cypermethrin


title: TP0001651B05_2_0.100000uM_DMEM_6h_TC00283151_J24

description:
TP0001651B05_2_0.100000uM_DMEM_6h
TC00283151_J24

value: 6h exposure of 0.1 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651D01_7_30.000000uM_DMEM_6h_TC00283151_J18

description:
TP0001651D01_7_30.000000uM_DMEM_6h
TC00283151_J18

value: 6h exposure of 30 uM of Lactofen

value: Lactofen


title: TP0001651B01_6_10.000000uM_DMEM_6h_TC00283151_J19

description:
TP0001651B01_6_10.000000uM_DMEM_6h
TC00283151_J19

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Cyanazine

value: Cyanazine

value: 10 uM


title: TP0001651A06_6_10.000000uM_DMEM_6h_TC00283151_J23

description:
TP0001651A06_6_10.000000uM_DMEM_6h
TC00283151_J23

value: 6h exposure of 10 uM of Cyproconazole

value: Cyproconazole


title: TP0001651H05_4_1.000000uM_DMEM_6h_TC00283151_K02

description:
TP0001651H05_4_1.000000uM_DMEM_6h
TC00283151_K02

value: 6h exposure of 1 uM of Trifloxystrobin

value: Trifloxystrobin

value: 1 uM


title: TP0001651C04_7_30.000000uM_DMEM_6h_TC00283151_J16

description:
TP0001651C04_7_30.000000uM_DMEM_6h
TC00283151_J16

value: 6h exposure of 30 uM of Simvastatin

value: Simvastatin


title: TP0001651H03_7_30.000000uM_DMEM_6h_TC00283151_J20

description:
TP0001651H03_7_30.000000uM_DMEM_6h
TC00283151_J20

value: 6h exposure of 30 uM of Fomesafen

value: Fomesafen

value: 30 uM


title: TP0001651E03_1_0.030000uM_DMEM_6h_TC00283151_J13

description:
TP0001651E03_1_0.030000uM_DMEM_6h
TC00283151_J13

value: 6h exposure of 0.03 uM of Prochloraz

value: Prochloraz


title: TP0001651B06_3_0.300000uM_DMEM_6h_TC00283151_J15

description:
TP0001651B06_3_0.300000uM_DMEM_6h
TC00283151_J15

value: 6h exposure of 0.3 uM of Troglitazone

value: Troglitazone


title: TP0001651C03_2_0.100000uM_DMEM_6h_TC00283151_J11

description:
TP0001651C03_2_0.100000uM_DMEM_6h
TC00283151_J11

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of Simazine

value: Simazine


title: TP0001651F04_3_0.300000uM_DMEM_6h_TC00283151_K03

description:
TP0001651F04_3_0.300000uM_DMEM_6h
TC00283151_K03

value: 6h exposure of 0.3 uM of Fulvestrant

value: Fulvestrant


title: TP0001651C03_5_3.000000uM_DMEM_6h_TC00283151_J12

description:
TP0001651C03_5_3.000000uM_DMEM_6h
TC00283151_J12

value: 6h exposure of 3 uM of Simazine

value: 3 uM


title: TP0001651H04_5_3.000000uM_DMEM_6h_TC00283151_J07

description:
TP0001651H04_5_3.000000uM_DMEM_6h
TC00283151_J07

value: 6h exposure of 3 uM of Bisphenol A

value: Bisphenol A


title: TP0001651G01_4_1.000000uM_DMEM_6h_TC00283151_J10

description:
TP0001651G01_4_1.000000uM_DMEM_6h
TC00283151_J10

value: 6h exposure of 1 uM of Vinclozolin

value: Vinclozolin

value: 1 uM


title: TSA_DMEM_6h_TC00283151_J06

description:
TSA_DMEM_6h
TC00283151_J06

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A


title: TP0001651H04_6_10.000000uM_DMEM_6h_TC00283151_J08

description:
TP0001651H04_6_10.000000uM_DMEM_6h
TC00283151_J08

value: 6h exposure of 10 uM of Bisphenol A

value: 10 uM


title: TP0001651B04_7_30.000000uM_DMEM_6h_TC00283151_J05

description:
TP0001651B04_7_30.000000uM_DMEM_6h
TC00283151_J05

value: 6h exposure of 30 uM of Propiconazole

value: Propiconazole

value: 30 uM


title: TP0001651G03_6_10.000000uM_DMEM_6h_TC00283151_J02

description:
TP0001651G03_6_10.000000uM_DMEM_6h
TC00283151_J02

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Nilutamide

value: Nilutamide


title: TP0001651C02_2_0.100000uM_DMEM_6h_TC00283151_J04

description:
TP0001651C02_2_0.100000uM_DMEM_6h
TC00283151_J04

value: 6h exposure of 0.1 uM of 4-Hydroxytamoxifen


title: TP0001651B05_7_30.000000uM_DMEM_6h_TC00283151_J03

description:
TP0001651B05_7_30.000000uM_DMEM_6h
TC00283151_J03

value: 6h exposure of 30 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651F05_7_30.000000uM_DMEM_6h_TC00283151_J21

description:
TP0001651F05_7_30.000000uM_DMEM_6h
TC00283151_J21

value: 6h exposure of 30 uM of Fenofibrate

value: Fenofibrate


title: TP0001651G01_3_0.300000uM_DMEM_6h_TC00283151_I24

description:
TP0001651G01_3_0.300000uM_DMEM_6h
TC00283151_I24

value: 6h exposure of 0.3 uM of Vinclozolin

value: Vinclozolin


title: TP0001651B01_3_0.300000uM_DMEM_6h_TC00283151_J17

description:
TP0001651B01_3_0.300000uM_DMEM_6h
TC00283151_J17

value: 6h exposure of 0.3 uM of Cyanazine

value: Cyanazine


title: TP0001651C01_8_100.000000uM_DMEM_6h_TC00283151_I22

description:
TP0001651C01_8_100.000000uM_DMEM_6h
TC00283151_I22

value: 6h exposure of 100 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651A06_2_0.100000uM_DMEM_6h_TC00283151_I23

description:
TP0001651A06_2_0.100000uM_DMEM_6h
TC00283151_I23

value: 6h exposure of 0.1 uM of Cyproconazole

value: Cyproconazole


title: Lysis Buffer_TC00283151_J01

description:
Lysis Buffer
TC00283151_J01

source_name: Lysis Buffer

value: Lysis Buffer

value: untreated


title: TP0001651F02_3_0.300000uM_DMEM_6h_TC00283151_J14

description:
TP0001651F02_3_0.300000uM_DMEM_6h
TC00283151_J14

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.3 uM of Ziram

value: Ziram


title: TP0001651F05_3_0.300000uM_DMEM_6h_TC00283151_I19

description:
TP0001651F05_3_0.300000uM_DMEM_6h
TC00283151_I19

value: 6h exposure of 0.3 uM of Fenofibrate


title: TP0001651E05_5_3.000000uM_DMEM_6h_TC00283151_I21

description:
TP0001651E05_5_3.000000uM_DMEM_6h
TC00283151_I21

value: 6h exposure of 3 uM of Atrazine

value: Atrazine

value: 3 uM


title: TP0001651D04_4_1.000000uM_DMEM_6h_TC00283151_I16

description:
TP0001651D04_4_1.000000uM_DMEM_6h
TC00283151_I16

value: 6h exposure of 1 uM of Clofibrate

value: Clofibrate

value: 1 uM


title: TP0001651G03_4_1.000000uM_DMEM_6h_TC00283151_I13

description:
TP0001651G03_4_1.000000uM_DMEM_6h
TC00283151_I13

value: 6h exposure of 1 uM of Nilutamide

value: Nilutamide


title: TP0001651E01_8_100.000000uM_DMEM_6h_TC00283151_I15

description:
TP0001651E01_8_100.000000uM_DMEM_6h
TC00283151_I15

value: 6h exposure of 100 uM of Bifenthrin

value: Bifenthrin


title: TP0001651B02_6_10.000000uM_DMEM_6h_TC00283151_J09

description:
TP0001651B02_6_10.000000uM_DMEM_6h
TC00283151_J09

value: 6h exposure of 10 uM of 3,5,3'-Triiodothyronine

value: 10 uM


title: TP0001651A03_7_30.000000uM_DMEM_6h_TC00283151_I18

description:
TP0001651A03_7_30.000000uM_DMEM_6h
TC00283151_I18

value: 6h exposure of 30 uM of Butafenacil

value: Butafenacil

value: 30 uM


title: TP0001651C06_8_100.000000uM_DMEM_6h_TC00283151_I17

description:
TP0001651C06_8_100.000000uM_DMEM_6h
TC00283151_I17

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Cycloheximide

value: Cycloheximide


title: DMSO_DMEM_6h_TC00283151_I12

description:
DMSO_DMEM_6h
TC00283151_I12

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651A06_8_100.000000uM_DMEM_6h_TC00283151_I10

description:
TP0001651A06_8_100.000000uM_DMEM_6h
TC00283151_I10

value: 6h exposure of 100 uM of Cyproconazole

value: Cyproconazole


title: TP0001651D05_1_0.030000uM_DMEM_6h_TC00283151_I08

description:
TP0001651D05_1_0.030000uM_DMEM_6h
TC00283151_I08

value: 6h exposure of 0.03 uM of Thiram

value: Thiram


title: TP0001651D04_3_0.300000uM_DMEM_6h_TC00283151_I05

description:
TP0001651D04_3_0.300000uM_DMEM_6h
TC00283151_I05

value: 6h exposure of 0.3 uM of Clofibrate

value: Clofibrate


title: TP0001651B06_1_0.030000uM_DMEM_6h_TC00283151_I11

description:
TP0001651B06_1_0.030000uM_DMEM_6h
TC00283151_I11

value: 6h exposure of 0.03 uM of Troglitazone

value: Troglitazone


title: TP0001651B06_8_100.000000uM_DMEM_6h_TC00283151_I07

description:
TP0001651B06_8_100.000000uM_DMEM_6h
TC00283151_I07

value: 6h exposure of 100 uM of Troglitazone


title: TP0001651E02_1_0.030000uM_DMEM_6h_TC00283151_I04

description:
TP0001651E02_1_0.030000uM_DMEM_6h
TC00283151_I04

value: 6h exposure of 0.03 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651D03_8_100.000000uM_DMEM_6h_TC00283151_I06

description:
TP0001651D03_8_100.000000uM_DMEM_6h
TC00283151_I06

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Cypermethrin

value: Cypermethrin


title: TP0001651H05_3_0.300000uM_DMEM_6h_TC00283151_I03

description:
TP0001651H05_3_0.300000uM_DMEM_6h
TC00283151_I03

value: 6h exposure of 0.3 uM of Trifloxystrobin

value: Trifloxystrobin


title: Lysis Buffer_TC00283151_I01

description:
Lysis Buffer
TC00283151_I01

value: Lysis Buffer

value: untreated


title: TP0001651C01_2_0.100000uM_DMEM_6h_TC00283151_I20

description:
TP0001651C01_2_0.100000uM_DMEM_6h
TC00283151_I20

value: 6h exposure of 0.1 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651E04_1_0.030000uM_DMEM_6h_TC00283151_H23

description:
TP0001651E04_1_0.030000uM_DMEM_6h
TC00283151_H23

value: 6h exposure of 0.03 uM of Farglitazar

value: Farglitazar


title: TP0001651C02_7_30.000000uM_DMEM_6h_TC00283151_H24

description:
TP0001651C02_7_30.000000uM_DMEM_6h
TC00283151_H24

value: 6h exposure of 30 uM of 4-Hydroxytamoxifen

value: 30 uM


title: TP0001651G02_8_100.000000uM_DMEM_6h_TC00283151_I14

description:
TP0001651G02_8_100.000000uM_DMEM_6h
TC00283151_I14

value: 6h exposure of 100 uM of Lovastatin

value: Lovastatin


title: GEN_DMEM_6h_TC00283151_H22

description:
GEN_DMEM_6h
TC00283151_H22

value: 6h exposure of 10 uM of Genistein

value: Genistein

value: 10 uM


title: TP0001651D03_7_30.000000uM_DMEM_6h_TC00283151_H21

description:
TP0001651D03_7_30.000000uM_DMEM_6h
TC00283151_H21

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Cypermethrin


title: TP0001651D03_5_3.000000uM_DMEM_6h_TC00283151_H20

description:
TP0001651D03_5_3.000000uM_DMEM_6h
TC00283151_H20

value: 6h exposure of 3 uM of Cypermethrin

value: Cypermethrin

value: 3 uM


title: Untrtd_DMEM_6h_TC00283151_H19

description:
Untrtd_DMEM_6h
TC00283151_H19

value: untreated


title: TP0001651D06_2_0.100000uM_DMEM_6h_TC00283151_H17

description:
TP0001651D06_2_0.100000uM_DMEM_6h
TC00283151_H17

value: 6h exposure of 0.1 uM of PFOS

value: PFOS


title: TP0001651A01_3_0.300000uM_DMEM_6h_TC00283151_H16

description:
TP0001651A01_3_0.300000uM_DMEM_6h
TC00283151_H16

value: 6h exposure of 0.3 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651G01_1_0.030000uM_DMEM_6h_TC00283151_H14

description:
TP0001651G01_1_0.030000uM_DMEM_6h
TC00283151_H14

value: 6h exposure of 0.03 uM of Vinclozolin

value: Vinclozolin


title: TP0001651G04_1_0.030000uM_DMEM_6h_TC00283151_H13

description:
TP0001651G04_1_0.030000uM_DMEM_6h
TC00283151_H13

value: 6h exposure of 0.03 uM of Cladribine

value: Cladribine


title: TP0001651E05_2_0.100000uM_DMEM_6h_TC00283151_H12

description:
TP0001651E05_2_0.100000uM_DMEM_6h
TC00283151_H12

value: 6h exposure of 0.1 uM of Atrazine

value: Atrazine


title: TP0001651G05_2_0.100000uM_DMEM_6h_TC00283151_H18

description:
TP0001651G05_2_0.100000uM_DMEM_6h
TC00283151_H18

value: 6h exposure of 0.1 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651H05_8_100.000000uM_DMEM_6h_TC00283151_H10

description:
TP0001651H05_8_100.000000uM_DMEM_6h
TC00283151_H10

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651F05_1_0.030000uM_DMEM_6h_TC00283151_H09

description:
TP0001651F05_1_0.030000uM_DMEM_6h
TC00283151_H09

value: 6h exposure of 0.03 uM of Fenofibrate

value: Fenofibrate


title: TP0001651C03_6_10.000000uM_DMEM_6h_TC00283151_H08

description:
TP0001651C03_6_10.000000uM_DMEM_6h
TC00283151_H08

value: 6h exposure of 10 uM of Simazine

value: Simazine

value: 10 uM


title: TP0001651G03_8_100.000000uM_DMEM_6h_TC00283151_H07

description:
TP0001651G03_8_100.000000uM_DMEM_6h
TC00283151_H07

value: 6h exposure of 100 uM of Nilutamide

value: Nilutamide


title: TP0001651F03_2_0.100000uM_DMEM_6h_TC00283151_H11

description:
TP0001651F03_2_0.100000uM_DMEM_6h
TC00283151_H11

value: 6h exposure of 0.1 uM of 4-Cumylphenol


title: TP0001651C02_1_0.030000uM_DMEM_6h_TC00283151_H05

description:
TP0001651C02_1_0.030000uM_DMEM_6h
TC00283151_H05

value: 6h exposure of 0.03 uM of 4-Hydroxytamoxifen


title: TP0001651C04_2_0.100000uM_DMEM_6h_TC00283151_H04

description:
TP0001651C04_2_0.100000uM_DMEM_6h
TC00283151_H04

value: 6h exposure of 0.1 uM of Simvastatin

value: Simvastatin


title: TP0001651A06_4_1.000000uM_DMEM_6h_TC00283151_H06

description:
TP0001651A06_4_1.000000uM_DMEM_6h
TC00283151_H06

value: 6h exposure of 1 uM of Cyproconazole

value: Cyproconazole

value: 1 uM


title: BL_TSA_TC00283151_H01

description:
BL_TSA
TC00283151_H01

value: DMEM + 10% HI-FBS

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A


title: GEN_DMEM_6h_TC00283151_G24

description:
GEN_DMEM_6h
TC00283151_G24

value: 6h exposure of 10 uM of Genistein

value: Genistein


title: TP0001651D05_3_0.300000uM_DMEM_6h_TC00283151_G23

description:
TP0001651D05_3_0.300000uM_DMEM_6h
TC00283151_G23

value: 6h exposure of 0.3 uM of Thiram

value: Thiram


title: TP0001651G01_7_30.000000uM_DMEM_6h_TC00283151_I02

description:
TP0001651G01_7_30.000000uM_DMEM_6h
TC00283151_I02

value: 6h exposure of 30 uM of Vinclozolin

value: Vinclozolin

value: 30 uM


title: TP0001651B01_8_100.000000uM_DMEM_6h_TC00283151_H03

description:
TP0001651B01_8_100.000000uM_DMEM_6h
TC00283151_H03

value: 6h exposure of 100 uM of Cyanazine

value: Cyanazine


title: TP0001651C02_4_1.000000uM_DMEM_6h_TC00283151_H15

description:
TP0001651C02_4_1.000000uM_DMEM_6h
TC00283151_H15

value: 6h exposure of 1 uM of 4-Hydroxytamoxifen


title: TP0001651C05_4_1.000000uM_DMEM_6h_TC00283151_G21

description:
TP0001651C05_4_1.000000uM_DMEM_6h
TC00283151_G21

value: 6h exposure of 1 uM of Bisphenol B

value: Bisphenol B


title: TP0001651A05_8_100.000000uM_DMEM_6h_TC00283151_G20

description:
TP0001651A05_8_100.000000uM_DMEM_6h
TC00283151_G20

value: 6h exposure of 100 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651E03_6_10.000000uM_DMEM_6h_TC00283151_G18

description:
TP0001651E03_6_10.000000uM_DMEM_6h
TC00283151_G18

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Prochloraz

value: Prochloraz

value: 10 uM


title: TP0001651C05_8_100.000000uM_DMEM_6h_TC00283151_G19

description:
TP0001651C05_8_100.000000uM_DMEM_6h
TC00283151_G19

value: 6h exposure of 100 uM of Bisphenol B


title: TP0001651G01_8_100.000000uM_DMEM_6h_TC00283151_G17

description:
TP0001651G01_8_100.000000uM_DMEM_6h
TC00283151_G17

value: 6h exposure of 100 uM of Vinclozolin


title: TP0001651A02_4_1.000000uM_DMEM_6h_TC00283151_G22

description:
TP0001651A02_4_1.000000uM_DMEM_6h
TC00283151_G22

value: 6h exposure of 1 uM of Imazalil

value: Imazalil

value: 1 uM


title: TP0001651H05_6_10.000000uM_DMEM_6h_TC00283151_G16

description:
TP0001651H05_6_10.000000uM_DMEM_6h
TC00283151_G16

value: 6h exposure of 10 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651E02_6_10.000000uM_DMEM_6h_TC00283151_G13

description:
TP0001651E02_6_10.000000uM_DMEM_6h
TC00283151_G13

value: 6h exposure of 10 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651C02_8_100.000000uM_DMEM_6h_TC00283151_G14

description:
TP0001651C02_8_100.000000uM_DMEM_6h
TC00283151_G14

value: 6h exposure of 100 uM of 4-Hydroxytamoxifen


title: TP0001651A01_1_0.030000uM_DMEM_6h_TC00283151_G12

description:
TP0001651A01_1_0.030000uM_DMEM_6h
TC00283151_G12

value: 6h exposure of 0.03 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651B05_4_1.000000uM_DMEM_6h_TC00283151_G11

description:
TP0001651B05_4_1.000000uM_DMEM_6h
TC00283151_G11

value: 6h exposure of 1 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651G05_4_1.000000uM_DMEM_6h_TC00283151_G08

description:
TP0001651G05_4_1.000000uM_DMEM_6h
TC00283151_G08

value: DMEM + 10% HI-FBS

value: 6h exposure of 1 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651G01_6_10.000000uM_DMEM_6h_TC00283151_G09

description:
TP0001651G01_6_10.000000uM_DMEM_6h
TC00283151_G09

value: 6h exposure of 10 uM of Vinclozolin

value: Vinclozolin

value: 10 uM


title: TP0001651B02_8_100.000000uM_DMEM_6h_TC00283151_H02

description:
TP0001651B02_8_100.000000uM_DMEM_6h
TC00283151_H02

value: 6h exposure of 100 uM of 3,5,3'-Triiodothyronine


title: TP0001651A05_1_0.030000uM_DMEM_6h_TC00283151_G07

description:
TP0001651A05_1_0.030000uM_DMEM_6h
TC00283151_G07

value: 6h exposure of 0.03 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651B05_8_100.000000uM_DMEM_6h_TC00283151_G04

description:
TP0001651B05_8_100.000000uM_DMEM_6h
TC00283151_G04

value: 6h exposure of 100 uM of Amiodarone hydrochloride


title: TP0001651H04_1_0.030000uM_DMEM_6h_TC00283151_G06

description:
TP0001651H04_1_0.030000uM_DMEM_6h
TC00283151_G06

value: 6h exposure of 0.03 uM of Bisphenol A

value: Bisphenol A


title: TP0001651C01_7_30.000000uM_DMEM_6h_TC00283151_G03

description:
TP0001651C01_7_30.000000uM_DMEM_6h
TC00283151_G03

value: 6h exposure of 30 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)

value: 30 uM


title: TP0001651A04_8_100.000000uM_DMEM_6h_TC00283151_G02

description:
TP0001651A04_8_100.000000uM_DMEM_6h
TC00283151_G02

value: 6h exposure of 100 uM of Rotenone

value: Rotenone


title: BL_TSA_TC00283151_G01

description:
BL_TSA
TC00283151_G01

value: DMEM + 10% HI-FBS

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A

value: 1 uM


title: TP0001651B01_5_3.000000uM_DMEM_6h_TC00283151_F22

description:
TP0001651B01_5_3.000000uM_DMEM_6h
TC00283151_F22

value: 6h exposure of 3 uM of Cyanazine

value: Cyanazine

value: 3 uM


title: TP0001651A03_2_0.100000uM_DMEM_6h_TC00283151_F23

description:
TP0001651A03_2_0.100000uM_DMEM_6h
TC00283151_F23

value: 6h exposure of 0.1 uM of Butafenacil

value: Butafenacil


title: TP0001651B02_1_0.030000uM_DMEM_6h_TC00283151_F24

description:
TP0001651B02_1_0.030000uM_DMEM_6h
TC00283151_F24

value: 6h exposure of 0.03 uM of 3,5,3'-Triiodothyronine


title: TP0001651E02_2_0.100000uM_DMEM_6h_TC00283151_F20

description:
TP0001651E02_2_0.100000uM_DMEM_6h
TC00283151_F20

value: 6h exposure of 0.1 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651E05_3_0.300000uM_DMEM_6h_TC00283151_F21

description:
TP0001651E05_3_0.300000uM_DMEM_6h
TC00283151_F21

value: 6h exposure of 0.3 uM of Atrazine

value: Atrazine


title: DMSO_DMEM_6h_TC00283151_F19

description:
DMSO_DMEM_6h
TC00283151_F19

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651B06_6_10.000000uM_DMEM_6h_TC00283151_G15

description:
TP0001651B06_6_10.000000uM_DMEM_6h
TC00283151_G15

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Troglitazone

value: Troglitazone

value: 10 uM


title: TP0001651H03_2_0.100000uM_DMEM_6h_TC00283151_F17

description:
TP0001651H03_2_0.100000uM_DMEM_6h
TC00283151_F17

value: 6h exposure of 0.1 uM of Fomesafen

value: Fomesafen


title: SIRO_DMEM_6h_TC00283151_F14

description:
SIRO_DMEM_6h
TC00283151_F14

value: 6h exposure of 0.1 uM of Sirolimus

value: Sirolimus


title: TP0001651F03_4_1.000000uM_DMEM_6h_TC00283151_F13

description:
TP0001651F03_4_1.000000uM_DMEM_6h
TC00283151_F13

value: 6h exposure of 1 uM of 4-Cumylphenol

value: 1 uM


title: TP0001651E04_2_0.100000uM_DMEM_6h_TC00283151_F15

description:
TP0001651E04_2_0.100000uM_DMEM_6h
TC00283151_F15

value: 6h exposure of 0.1 uM of Farglitazar

value: Farglitazar


title: TP0001651D01_1_0.030000uM_DMEM_6h_TC00283151_F18

description:
TP0001651D01_1_0.030000uM_DMEM_6h
TC00283151_F18

value: 6h exposure of 0.03 uM of Lactofen

value: Lactofen


title: TP0001651H05_5_3.000000uM_DMEM_6h_TC00283151_F12

description:
TP0001651H05_5_3.000000uM_DMEM_6h
TC00283151_F12

value: 6h exposure of 3 uM of Trifloxystrobin

value: Trifloxystrobin

value: 3 uM


title: TP0001651B01_2_0.100000uM_DMEM_6h_TC00283151_G10

description:
TP0001651B01_2_0.100000uM_DMEM_6h
TC00283151_G10

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of Cyanazine

value: Cyanazine


title: TP0001651G04_5_3.000000uM_DMEM_6h_TC00283151_F10

description:
TP0001651G04_5_3.000000uM_DMEM_6h
TC00283151_F10

value: 6h exposure of 3 uM of Cladribine

value: Cladribine


title: TP0001651F02_5_3.000000uM_DMEM_6h_TC00283151_F09

description:
TP0001651F02_5_3.000000uM_DMEM_6h
TC00283151_F09

value: 6h exposure of 3 uM of Ziram

value: Ziram


title: TP0001651G02_3_0.300000uM_DMEM_6h_TC00283151_F11

description:
TP0001651G02_3_0.300000uM_DMEM_6h
TC00283151_F11

value: 6h exposure of 0.3 uM of Lovastatin

value: Lovastatin


title: TP0001651A05_3_0.300000uM_DMEM_6h_TC00283151_F06

description:
TP0001651A05_3_0.300000uM_DMEM_6h
TC00283151_F06

value: 6h exposure of 0.3 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651F01_4_1.000000uM_DMEM_6h_TC00283151_G05

description:
TP0001651F01_4_1.000000uM_DMEM_6h
TC00283151_G05

value: 6h exposure of 1 uM of Tetrac

value: Tetrac

value: 1 uM


title: TP0001651G02_4_1.000000uM_DMEM_6h_TC00283151_F08

description:
TP0001651G02_4_1.000000uM_DMEM_6h
TC00283151_F08

value: 6h exposure of 1 uM of Lovastatin


title: TP0001651B05_3_0.300000uM_DMEM_6h_TC00283151_F05

description:
TP0001651B05_3_0.300000uM_DMEM_6h
TC00283151_F05

value: 6h exposure of 0.3 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651F01_7_30.000000uM_DMEM_6h_TC00283151_F07

description:
TP0001651F01_7_30.000000uM_DMEM_6h
TC00283151_F07

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Tetrac

value: 30 uM


title: TP0001651H04_7_30.000000uM_DMEM_6h_TC00283151_F03

description:
TP0001651H04_7_30.000000uM_DMEM_6h
TC00283151_F03

value: 6h exposure of 30 uM of Bisphenol A

value: Bisphenol A


title: TP0001651B03_7_30.000000uM_DMEM_6h_TC00283151_F02

description:
TP0001651B03_7_30.000000uM_DMEM_6h
TC00283151_F02

value: 6h exposure of 30 uM of Reserpine

value: Reserpine


title: TP0001651B05_1_0.030000uM_DMEM_6h_TC00283151_F16

description:
TP0001651B05_1_0.030000uM_DMEM_6h
TC00283151_F16

value: 6h exposure of 0.03 uM of Amiodarone hydrochloride


title: TP0001651E03_5_3.000000uM_DMEM_6h_TC00283151_E22

description:
TP0001651E03_5_3.000000uM_DMEM_6h
TC00283151_E22

value: 6h exposure of 3 uM of Prochloraz

value: Prochloraz

value: 3 uM


title: TP0001651B01_7_30.000000uM_DMEM_6h_TC00283151_E21

description:
TP0001651B01_7_30.000000uM_DMEM_6h
TC00283151_E21

value: 6h exposure of 30 uM of Cyanazine

value: Cyanazine


title: TP0001651D05_7_30.000000uM_DMEM_6h_TC00283151_E20

description:
TP0001651D05_7_30.000000uM_DMEM_6h
TC00283151_E20

value: 6h exposure of 30 uM of Thiram

value: Thiram


title: TP0001651A01_2_0.100000uM_DMEM_6h_TC00283151_E19

description:
TP0001651A01_2_0.100000uM_DMEM_6h
TC00283151_E19

value: 6h exposure of 0.1 uM of Pyraclostrobin

value: Pyraclostrobin


title: PAM-miRNA-PRRSV24h-2

city: harbin

first: gao

last: junxin

state: hei longjiang

address: haping street

country: China

institute: junxingao

description: endogenous miRNAs in PAMs

data_processing:
The miRNA library construction and sequencing were conducted with Illumina sequencing technology.
The sequence data were analyzed by GBI.
The miRNAs represented by > 20 reads were selected for differential expression testing.
The differential expression comparisons were made between time-matched mock and PRRSV infected PAMs.
Genome_build: sus scrofa miRNA (miRBase v21)
Supplementary_files_format_and_content: text files

organism: Sus scrofa

source_name: lung

growth_protocol: Primary PAMs were freshly isolated into 3 five-week-old SPF Landrace pigs.

extract_protocol:
Total RNA was extracted from cells with TRIzol
The miRNA library construction and sequencing were conducted with Illumina sequencing technology (BGI-Wuhan, China), and qualified sequence data were analyzed by GBI (Wuhan, China).
The eligible libraries were sequenced using Illumina HiSeqTM X TEN.

treatment_protocol: Primary PAMs were inoculated with PRRSV (MOI=5) or mock with the same volume.

tag: cell type

value: porcine alveolar macrophages (PAMs)

value: prrsv-infected

tag: age

value: 5 weeks

tag: breed

value: Landrace


title: PAM-miRNA-PRRSV24h-3

description: endogenous miRNAs in PAMs


title: GEN_DMEM_6h_TC00283151_E18

description:
GEN_DMEM_6h
TC00283151_E18

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Genistein

value: Genistein

value: 10 uM


title: PAM-miRNA-PRRSV24h-1

description: endogenous miRNAs in PAMs


title: TP0001651E05_1_0.030000uM_DMEM_6h_TC00283151_E17

description:
TP0001651E05_1_0.030000uM_DMEM_6h
TC00283151_E17

value: 6h exposure of 0.03 uM of Atrazine

value: Atrazine


title: PAM-miRNA-mock24h-2

description: endogenous miRNAs in PAMs

value: mock-incubated


title: PAM-miRNA-mock24h-1

description: endogenous miRNAs in PAMs


title: PAM-miRNA-mock24h-3

description: endogenous miRNAs in PAMs


title: PAM-miRNA-3

description: endogenous miRNAs in PAMs

value: untreated


title: PAM-miRNA-1

description: endogenous miRNAs in PAMs


title: TP0001651F01_8_100.000000uM_DMEM_6h_TC00283151_E16

description:
TP0001651F01_8_100.000000uM_DMEM_6h
TC00283151_E16

value: 6h exposure of 100 uM of Tetrac

value: Tetrac


title: DMSO_DMEM_6h_TC00283151_E14

description:
DMSO_DMEM_6h
TC00283151_E14

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: BL_DMSO_TC00283151_F01

description:
BL_DMSO
TC00283151_F01


title: TP0001651B06_4_1.000000uM_DMEM_6h_TC00283151_E15

description:
TP0001651B06_4_1.000000uM_DMEM_6h
TC00283151_E15

value: 6h exposure of 1 uM of Troglitazone

value: Troglitazone

value: 1 uM


title: TP0001651H03_1_0.030000uM_DMEM_6h_TC00283151_E10

description:
TP0001651H03_1_0.030000uM_DMEM_6h
TC00283151_E10

value: 6h exposure of 0.03 uM of Fomesafen

value: Fomesafen


title: LH17.3554

city: Valbonne - Sophia-Antipolis

first: Kevin

last: Lebrigand

address: 660 route des lucioles

country: France

institute: IPMC/CNRS

library_source: genomic

data_processing:
Library strategy: Exome-Seq
Raw reads were first filtered for quality control
Cleaned reads were aligned to the human genome release hg19 using Burrows-Wheeler Aligner (BWA) software.
Aligned reads were realigned to the genome. Duplicates were marked using MarkDuplicates from Picard tools. We utilized the Indelrealigner and RealignerTargetCreator from Genome Analysis Toolkit (GATK) to do realignment around the indels according to GATK best practice. We then performed base quality score recalibration with GATK to avoid system bias.
After realignment to genome, we identified and filtered variants (SNPs) using GATK HaplotypeCaller and variantFiltration.
Variants obtained from previous steps were annotated with ANNOVAR
Genome_build: hg19
Supplementary_files_format_and_content: vcf files: tab-delimited files include snp calling results

molecule: genomic DNA

source_name: Human uveal melanoma

extract_protocol:
Genomic DNA was prepared from patient’s blood sample using the DNeasy Blood and Tissue Kit (Qiagen ref #69504).
A total amount of 1.0μg genomic DNA per sample was used as input material for the DNA library preparation. Libraries were generated using Agilent SureSelect Human All Exon V6 kit (Agilent Technologies, CA, USA) following manufacturer's recommendations and whole exomes were sequenced on the Illumina HiSeq platform.

tag: gender

value: Male

tag: donor

tag: disease

value: Uveal Melanoma

tag: tissue

value: Eye


title: TP0001651D04_2_0.100000uM_DMEM_6h_TC00283151_E12

description:
TP0001651D04_2_0.100000uM_DMEM_6h
TC00283151_E12

tag: cell line

tag: media

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of Clofibrate

value: Clofibrate


title: TP0001651G03_1_0.030000uM_DMEM_6h_TC00283151_F04

description:
TP0001651G03_1_0.030000uM_DMEM_6h
TC00283151_F04

tag: treatment

value: 6h exposure of 0.03 uM of Nilutamide

tag: chemical name

value: Nilutamide


title: LH18.277


title: TP0001651E02_3_0.300000uM_DMEM_6h_TC00283151_E11

description:
TP0001651E02_3_0.300000uM_DMEM_6h
TC00283151_E11

value: 6h exposure of 0.3 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched

tag: chemical sample id

tag: chemical concentration


title: LH17.364


title: TP0001651A02_2_0.100000uM_DMEM_6h_TC00283151_E24

description:
TP0001651A02_2_0.100000uM_DMEM_6h
TC00283151_E24

value: 6h exposure of 0.1 uM of Imazalil

value: Imazalil

tag: dose level

tag: exposure time


title: TP0001651D06_8_100.000000uM_DMEM_6h_TC00283151_E06

description:
TP0001651D06_8_100.000000uM_DMEM_6h
TC00283151_E06

value: 6h exposure of 100 uM of PFOS

value: PFOS

tag: assay plate

tag: assay plate well


title: Dioxane 5000mg/mL rep3

city: New Haven

first: Rolando

last: Garcia-Milian

state: CT

address: 333 Cedar St

department: CWML

institute: Yale University

description:
female mouse
DX_VV9_CGCTCATT

data_processing:
RNA libraries were prepared according to the Illumina kit protocol after poly-A selection and sequenced on the HiSeq 2500 platform in a stranded paired-end manner.
Statistical analyses were performed using Partek Flow software (version 7.0, build 7.18.0130.2018 Partek Inc., St. Louis, MO, USA). Paired-end reads were trimmed using a base quality score threshold of >20 and aligned to the Genome Reference Consortium Mouse Build 38 (mm10) with the STAR 2.5.3a aligner. Quantification was carried out using the transcript model Ensembl Transcripts release 91. Differential expression analysis was performed using the R package DESeq2
Genome_build: mm10
Supplementary_files_format_and_content: tab-delimited text file include raw counts for each sample and each gene

organism: Mus musculus

source_name: Liver

extract_protocol:
mRNA (≈500 ng total) was purified with oligo-dT beads and sheared by incubation at 94°C (first-strand synthesis with random primers). Second strand synthesis was performed using dUTP to generate strand-specific sequencing libraries. The cDNA library was then end-repaired, A-tailed adapters were ligated, and second-strand digestion was performed using uracil-DNA-glycosylase. Indexed libraries (that met appropriate cut-offs for both) were quantified by qRT-PCR using a commercially-available kit (KAPA Biosystems), and insert size distribution was determined using a LabChip GX or Agilent Bioanalyzer. Samples with a yield ≥0.5 ng/µL were used for sequencing.
RNA libraries were prepared for sequencing using standard Illumina protocols

treatment_protocol: Three week old female BDF1 mice treated with 1,4-Dioxane (50, 500 or 5,000 mg/L) in drinking water for 4 weeks

tag: strain

value: liver

value: 3-weeks old

tag: genotype

value: wild type

tag: Sex

value: female

value: Dioxane 5000mg/mL


title: TP0001651C03_1_0.030000uM_DMEM_6h_TC00283151_E05

description:
TP0001651C03_1_0.030000uM_DMEM_6h
TC00283151_E05

value: 6h exposure of 0.03 uM of Simazine

value: Simazine


title: PAM-miRNA-2

description: endogenous miRNAs in PAMs

tag: cell type

value: porcine alveolar macrophages (PAMs)

value: untreated

tag: age

value: 5 weeks

tag: breed

value: Landrace


title: TP0001651D04_7_30.000000uM_DMEM_6h_TC00283151_E23

description:
TP0001651D04_7_30.000000uM_DMEM_6h
TC00283151_E23

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of Clofibrate

value: Clofibrate

value: 30 uM


title: Untrtd_DMEM_6h_TC00283151_E03

description:
Untrtd_DMEM_6h
TC00283151_E03


title: Dioxane 50mg/mL rep3

description:
female mouse
DX_VV6_AGCGATAG

tag: tissue

value: Dioxane 50mg/mL


title: Dioxane 50mg/mL rep2

description:
female mouse
DX_VV5_TCTCGCGC


title: TP0001651H05_2_0.100000uM_DMEM_6h_TC00283151_E02

description:
TP0001651H05_2_0.100000uM_DMEM_6h
TC00283151_E02

tag: cell line

value: 6h exposure of 0.1 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651B02_3_0.300000uM_DMEM_6h_TC00283151_E09

description:
TP0001651B02_3_0.300000uM_DMEM_6h
TC00283151_E09

tag: media

value: 6h exposure of 0.3 uM of 3,5,3'-Triiodothyronine


title: LH17.530

tag: gender

value: Male

tag: donor

tag: disease

value: Uveal Melanoma

value: Eye


title: LH17.3222


title: BL_DMSO_TC00283151_E01

description:
BL_DMSO
TC00283151_E01

tag: treatment

value: 0.5% DMSO vehicle control

tag: chemical name

value: DMSO

tag: chemical sample id

tag: chemical concentration

value: 0 uM


title: TP0001651F05_6_10.000000uM_DMEM_6h_TC00283151_E08

description:
TP0001651F05_6_10.000000uM_DMEM_6h
TC00283151_E08

value: 6h exposure of 10 uM of Fenofibrate

value: Fenofibrate

value: 10 uM

tag: dose level

tag: exposure time

tag: assay plate

tag: assay plate well


title: Dioxane 0mg/mL rep3

description:
female mouse
DX_VV3_CGGCTATG

tag: strain

value: liver

value: 3-weeks old

tag: genotype

value: wild type

tag: Sex

value: female

value: Dioxane 0mg/mL


title: TP0001651H02_6_10.000000uM_DMEM_6h_TC00283151_E07

description:
TP0001651H02_6_10.000000uM_DMEM_6h
TC00283151_E07

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Maneb

value: Maneb


title: Dioxane 50mg/mL rep1

description:
female mouse
DX_VV4_TCCGCGAA

tag: tissue

tag: age

value: Dioxane 50mg/mL


title: Dioxane 5000mg/mL rep2

description:
female mouse
DX_VV8_TCCGGAGA

value: Dioxane 5000mg/mL


title: LH16.3814

value: Female

value: Uveal Melanoma

value: Eye


title: Dioxane 0mg/mL rep2

description:
female mouse
DX_VV2_TAATGCGC


title: Dioxane 0mg/mL rep1

description:
female mouse
DX_VV1_CTGAAGCT


title: TP0001651F03_5_3.000000uM_DMEM_6h_TC00283151_D22

description:
TP0001651F03_5_3.000000uM_DMEM_6h
TC00283151_D22

tag: cell line

tag: media

value: 6h exposure of 3 uM of 4-Cumylphenol

value: 3 uM


title: TP0001651C05_2_0.100000uM_DMEM_6h_TC00283151_E13

description:
TP0001651C05_2_0.100000uM_DMEM_6h
TC00283151_E13

value: 6h exposure of 0.1 uM of Bisphenol B

value: Bisphenol B


title: TP0001651E03_4_1.000000uM_DMEM_6h_TC00283151_E04

description:
TP0001651E03_4_1.000000uM_DMEM_6h
TC00283151_E04

value: 6h exposure of 1 uM of Prochloraz

value: Prochloraz

value: 1 uM


title: TP0001651A04_2_0.100000uM_DMEM_6h_TC00283151_D21

description:
TP0001651A04_2_0.100000uM_DMEM_6h
TC00283151_D21

value: 6h exposure of 0.1 uM of Rotenone

value: Rotenone


title: TP0001651D01_8_100.000000uM_DMEM_6h_TC00283151_D19

description:
TP0001651D01_8_100.000000uM_DMEM_6h
TC00283151_D19

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Lactofen

value: Lactofen


title: Dioxane 5000mg/mL rep1

description:
female mouse
DX_VV7_ATTACTCG

value: liver

value: 3-weeks old

value: wild type

value: female


title: TP0001651H02_2_0.100000uM_DMEM_6h_TC00283151_D23

description:
TP0001651H02_2_0.100000uM_DMEM_6h
TC00283151_D23

value: 6h exposure of 0.1 uM of Maneb

value: Maneb


title: TP0001651F02_6_10.000000uM_DMEM_6h_TC00283151_D20

description:
TP0001651F02_6_10.000000uM_DMEM_6h
TC00283151_D20

value: 6h exposure of 10 uM of Ziram

value: Ziram

value: 10 uM


title: Frontal cortex cells in WT background

city: Bethesda

first: Vivek

last: Mahadevan

state: Maryland

address: 35, Convent Drive

department: aSection on Cellular and Synaptic Physiology

institute: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

data_processing:
Basecalling was performed using Illumina HiSeq2500 Control software.
BAM files were generated using 10X Genomics Cellranger version 2.1.1 with default paramaters
Gene-barcode matrices were determined using 10X Genomics Cellranger version 2.1.1 with default parameters
Genome_build: mm10
Supplementary_files_format_and_content: Gene-barcode matrices,  gene features files and barcode files were generated by 10X Genomics CellRanger and are described at https://support.10xgenomics.com/single-cell-gene-expression/software/pipelines/latest/output/overview.

source_name: Acute frontal cortex slices

extract_protocol:
Cell dissociations were performed using the Worthington Papain Dissociation System. Ai14-TdTomato expressing cells, indicating Nkx2.1-cell-type specificity, were sorted by FACS.
The cells were inspected for viability, counted, and loaded on the 10X Genomics Chromium system, aiming to recover ~5000 cells per condition. 12 PCR cycles were conducted for cDNA amplification, and the subsequent library preparation and sequencing were carried out in accordance with the manufacturer recommendation (Chromium™ Single Cell 3' Library & Gel Bead Kit v2 and v3, 16 rxns). Sequencing of the libraries were performed on the Illumina HiSeq2500.

value: Brain

tag: cell type

value: Nkx2.1-cell-type specific Frontal cortex cells

tag: developmental stage

value: Juvenile (postnatal day 18-20)


title: Hippocampus cells in MGE-derived interneuron-specific GRIN1-KO background

source_name: Acute hippocampus slices

value: Nkx2.1-cell-type specific Hippocampus  cells


title: TP0001651H01_1_0.030000uM_DMEM_6h_TC00283151_D17

description:
TP0001651H01_1_0.030000uM_DMEM_6h
TC00283151_D17

tag: treatment

value: 6h exposure of 0.03 uM of Flutamide

value: Flutamide


title: Hippocampus cells in WT background

value: Nkx2.1-cell-type specific Hippocampus cells


title: TP0001651B03_6_10.000000uM_DMEM_6h_TC00283151_D18

description:
TP0001651B03_6_10.000000uM_DMEM_6h
TC00283151_D18

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Reserpine

tag: chemical name

value: Reserpine


title: TP0001651F01_1_0.030000uM_DMEM_6h_TC00283151_D16

description:
TP0001651F01_1_0.030000uM_DMEM_6h
TC00283151_D16

value: 6h exposure of 0.03 uM of Tetrac

value: Tetrac

tag: chemical sample id


title: P56_5_Striatum

city: Basel

first: Roland

last: Schmucki

address: Grenzacherstrase

country: Switzerland

institute: F. Hoffmann - La Roche AG

data_processing:
Basecalling and sample de-multiplexing was performed with CASAVA-1.8.4 and default parameters
Reads were quality check with fastqc v0.11.5 default parameters
Reads for each sample/replicate were mapped against the mouse genome assembly and counted using STAR read aligner v2.7.3a
Antisense contigs were assembled using the Trinity platform v2.8.4
Genome_build: Ensembl GRCm38 with assembled antisense contigs
Supplementary_files_format_and_content: Read counts per gene/contig

extract_protocol:
Total RNA including miRNA fractions were isolated using Qiagen miRNeasy mini kit according to the manufacturer’s protocol. RNA integrity was assessed with an Agilent 2100 Bioanalyzer using an Agilent Bioanalyzer 6000 Nano kit.
Input of 400ng of total RNA was used as starting material for each sample and libraries were prepared using 99 TruSeq Stranded Total RNA LT with Ribo-Zero Gold Depletion Kit from Illumina. Quantification was performed using KAPA Library Quantification Kit and the average size of 300 bp was determined by using a High Sensitivity DNA Kit. The libraries were pooled and diluted to 13 pM to load on an Illumina HiSeq 2500 Instrument.

value: post natal day 56

value: striatum

tag: replicate


title: Frontal cortex cells in MGE-derived interneuron-specific GRIN1-KO background


title: TP0001651D06_4_1.000000uM_DMEM_6h_TC00283151_D15

description:
TP0001651D06_4_1.000000uM_DMEM_6h
TC00283151_D15

value: 6h exposure of 1 uM of PFOS

value: PFOS

tag: chemical concentration

value: 1 uM

tag: dose level


title: P56_4_Striatum


title: TP0001651E03_7_30.000000uM_DMEM_6h_TC00283151_D24

description:
TP0001651E03_7_30.000000uM_DMEM_6h
TC00283151_D24

value: 6h exposure of 30 uM of Prochloraz

value: Prochloraz

value: 30 uM

tag: exposure time

tag: assay plate


title: P56_3_Striatum

tag: strain


title: TP0001651F02_2_0.100000uM_DMEM_6h_TC00283151_D13

description:
TP0001651F02_2_0.100000uM_DMEM_6h
TC00283151_D13

value: 6h exposure of 0.1 uM of Ziram

value: Ziram

tag: assay plate well


title: TP0001651H03_5_3.000000uM_DMEM_6h_TC00283151_D11

description:
TP0001651H03_5_3.000000uM_DMEM_6h
TC00283151_D11

value: 6h exposure of 3 uM of Fomesafen

value: Fomesafen

value: 3 uM


title: TP0001651D02_7_30.000000uM_DMEM_6h_TC00283151_D14

description:
TP0001651D02_7_30.000000uM_DMEM_6h
TC00283151_D14

value: DMEM + 10% HI-FBS

value: 6h exposure of 30 uM of PFOA

value: PFOA


title: TP0001651F01_3_0.300000uM_DMEM_6h_TC00283151_D10

description:
TP0001651F01_3_0.300000uM_DMEM_6h
TC00283151_D10

value: 6h exposure of 0.3 uM of Tetrac

value: Tetrac


title: TP0001651B05_5_3.000000uM_DMEM_6h_TC00283151_D09

description:
TP0001651B05_5_3.000000uM_DMEM_6h
TC00283151_D09

value: 6h exposure of 3 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: P14_3_Striatum

value: post natal day 14

value: striatum


title: P56_1_Striatum

value: post natal day 56


title: P14_5_Striatum


title: TP0001651B02_7_30.000000uM_DMEM_6h_TC00283151_D12

description:
TP0001651B02_7_30.000000uM_DMEM_6h
TC00283151_D12

value: 6h exposure of 30 uM of 3,5,3'-Triiodothyronine


title: P14_4_Striatum


title: P14_2_Striatum


title: TP0001651F01_5_3.000000uM_DMEM_6h_TC00283151_D08

description:
TP0001651F01_5_3.000000uM_DMEM_6h
TC00283151_D08

value: 6h exposure of 3 uM of Tetrac


title: TP0001651A06_1_0.030000uM_DMEM_6h_TC00283151_D07

description:
TP0001651A06_1_0.030000uM_DMEM_6h
TC00283151_D07

value: 6h exposure of 0.03 uM of Cyproconazole

value: Cyproconazole


title: P14_1_Striatum


title: P7_2_Striatum

value: post natal day 7


title: TP0001651D06_6_10.000000uM_DMEM_6h_TC00283151_D06

description:
TP0001651D06_6_10.000000uM_DMEM_6h
TC00283151_D06

value: 6h exposure of 10 uM of PFOS

value: PFOS

value: 10 uM


title: TP0001651B03_8_100.000000uM_DMEM_6h_TC00283151_D05

description:
TP0001651B03_8_100.000000uM_DMEM_6h
TC00283151_D05

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Reserpine

value: Reserpine


title: P56_2_Striatum


title: P56_4_mPFC

value: medial prefrontal cortex (mPFC)


title: P7_1_Striatum


title: TP0001651D05_4_1.000000uM_DMEM_6h_TC00283151_D04

description:
TP0001651D05_4_1.000000uM_DMEM_6h
TC00283151_D04

value: 6h exposure of 1 uM of Thiram

value: Thiram

value: 1 uM


title: P56_2_mPFC


title: HBRR_TC00283151_D01

description:
HBRR
TC00283151_D01

source_name: Human Brain Reference RNA

tag: sample type

value: HBRR

value: untreated


title: P14_5_mPFC

value: post natal day 14

tag: tissue


title: TP0001651E02_7_30.000000uM_DMEM_6h_TC00283151_D02

description:
TP0001651E02_7_30.000000uM_DMEM_6h
TC00283151_D02

value: 6h exposure of 30 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched

value: 30 uM


title: P56_5_mPFC

tag: age

value: post natal day 56


title: TP0001651H02_1_0.030000uM_DMEM_6h_TC00283151_D03

description:
TP0001651H02_1_0.030000uM_DMEM_6h
TC00283151_D03

tag: cell line

value: 6h exposure of 0.03 uM of Maneb

value: Maneb


title: P14_4_mPFC


title: P56_1_mPFC


title: TP0001651D03_2_0.100000uM_DMEM_6h_TC00283151_C22

description:
TP0001651D03_2_0.100000uM_DMEM_6h
TC00283151_C22

tag: media

value: 6h exposure of 0.1 uM of Cypermethrin

value: Cypermethrin


title: TP0001651H01_2_0.100000uM_DMEM_6h_TC00283151_C21

description:
TP0001651H01_2_0.100000uM_DMEM_6h
TC00283151_C21

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of Flutamide

value: Flutamide


title: TP0001651B06_2_0.100000uM_DMEM_6h_TC00283151_C23

description:
TP0001651B06_2_0.100000uM_DMEM_6h
TC00283151_C23

value: 6h exposure of 0.1 uM of Troglitazone

value: Troglitazone


title: TP0001651C06_6_10.000000uM_DMEM_6h_TC00283151_C24

description:
TP0001651C06_6_10.000000uM_DMEM_6h
TC00283151_C24

value: 6h exposure of 10 uM of Cycloheximide

value: Cycloheximide

value: 10 uM


title: P14_3_mPFC

value: post natal day 14

value: medial prefrontal cortex (mPFC)


title: TP0001651C05_1_0.030000uM_DMEM_6h_TC00283151_C20

description:
TP0001651C05_1_0.030000uM_DMEM_6h
TC00283151_C20

value: 6h exposure of 0.03 uM of Bisphenol B

value: Bisphenol B


title: P14_1_mPFC


title: TP0001651F04_7_30.000000uM_DMEM_6h_TC00283151_C19

description:
TP0001651F04_7_30.000000uM_DMEM_6h
TC00283151_C19

value: 6h exposure of 30 uM of Fulvestrant

value: Fulvestrant

value: 30 uM


title: P14_2_mPFC


title: P7_2_mPFC

value: post natal day 7


title: TP0001651E01_4_1.000000uM_DMEM_6h_TC00283151_C18

description:
TP0001651E01_4_1.000000uM_DMEM_6h
TC00283151_C18

value: 6h exposure of 1 uM of Bifenthrin

value: Bifenthrin

value: 1 uM


title: P7_1_mPFC


title: TP0001651C06_2_0.100000uM_DMEM_6h_TC00283151_C17

description:
TP0001651C06_2_0.100000uM_DMEM_6h
TC00283151_C17

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.1 uM of Cycloheximide


title: TP0001651H01_8_100.000000uM_DMEM_6h_TC00283151_C15

description:
TP0001651H01_8_100.000000uM_DMEM_6h
TC00283151_C15

value: 6h exposure of 100 uM of Flutamide

value: Flutamide


title: P56_3_mPFC

value: post natal day 56


title: TP0001651D01_2_0.100000uM_DMEM_6h_TC00283151_C16

description:
TP0001651D01_2_0.100000uM_DMEM_6h
TC00283151_C16

value: 6h exposure of 0.1 uM of Lactofen

value: Lactofen


title: TP0001651F04_6_10.000000uM_DMEM_6h_TC00283151_C14

description:
TP0001651F04_6_10.000000uM_DMEM_6h
TC00283151_C14

value: 6h exposure of 10 uM of Fulvestrant

value: 10 uM


title: cmt2cmt3_HiC

city: Los Angeles

first: Zhenhui

last: Zhong

address: 610 Charles E Young Dr East

department: Department of Molecular, Cell and Developmental Biology

institute: University of California, Los Angeles

data_processing:
ATAC-seq read adaptors were removed with trim_galore and then mapped to the Arabidopsis thaliana reference genome TAIR10 using Bowtie (-X 2000 -m 1).
Reads aligned to chloroplast and mitochondrial DNA were filtered out and duplicated reads were removed using SAMtools.
ATAC-seq peaks were called by HMMRATAC with minlength 50 bp.
Paired-end Hi-C reads were aligned to tair10 with HiC-Pro (v2.11.1). Whole genome Hi-C heatmap was converted with juicer_tools (v1.13.02) and visualized with Juicebox (v1.11.08). Hi-C loops were called with analyzeHiC in Homer2 with 200 bp resolution and pvalue < 1e-10. The WashU EpiGenome Browser v46.2 (https://epgg-test.wustl.edu/browser/) was used to visualize Hi-C loops and ATAC-seq data. PC1 value of Hi-C data was calculated with Homer2. Regional Hi-C visualization was performed by hicexplorer (v3.4.3).
Genome_build: tair10
Supplementary_files_format_and_content: bigWig: ATAC-seq mapping file hic: Hi-C interaction file

organism: Arabidopsis thaliana

growth_protocol: Arabidopsis plants of the Columbia-0 (Col-0) ecotype were used in this study. All plants were grown at 22 °C in a long day (16 hour light, 8 hour dark) growth room. Flowers and leaves were collected from 4-5 week-old plants. For Hi-C, plants grown on agar plates at 21◦C under constant light for 14 days before seedling tissues (without roots) were harvested. Then, nuclei were isolated and flow–sorted from seedlings after formaldehyde fixation using a FACS Aria (BD Biosciences) according to their 2C and 4C ploidy level.

extract_protocol:
Inflorescence tissues were collected for nuclei extraction as follows. About 5 g of inflorescence tissue was collected and immediately transferred into ice-cold grinding buffer (300 mM sucrose, 20 mM Tris pH 8, 5 mM MgCl2, 5 mM KCl, 0.2% Triton X-100, 5 mM β-mercaptoethanol, 35% glycerol). The samples were ground with Omni International General Laboratory Homogenizer at 4 °C and then filtered through a two-layer Miracloth and a 40-µm nylon mesh Cell Strainer (Fisher). Samples were spin filtered for 10 min at 3,000 g, the supernatant was discarded, and the pellet was resuspended with 25 ml of grinding buffer using a Dounce homogenizer. The wash step was repeated once and the nuclei were resuspended in 0.5 ml of freezing buffer (50 mM Tris pH 8, 5 mM MgCl2, 20% glycerol, 5 mM β-mercaptoethanol).  Hi-C libraries for Illumina sequencing were generated53. The libraries were sequenced on HiSeq 2000 DNA sequencers obtaining paired-end 50- or 51-nucleotide reads following manufacturer instructions (Illumina).
Nuclei were subjected to transposition reaction with Tn5 (Illumina, cat. no. FC-121-1030). For transposition reaction, 25 µl of 2x DMF (66mM Tris-acetate (pH=7.8), 132 mM K-Acetate, 20mM Mg-Acetate, 32 % DMF) was mixed with 2.5 µl Tn5 and 22.5 µl nuclei suspension at 37 °C for 30 min. Transposed DNA fragments were purified with ChIP DNA Clean & Concentrator Kit (Zymo, cat. no. D5205). Libraries were preparated with Phusion High-Fidelity DNA Polymerase (NEB, cat. no. M0530S) (12.5µl 2x Phusion, 1.25µl 10 mM Ad1 primer, 1.25µl 10 mM Ad2 primer, 4 µl ddH2O and 6µl purified transposed DNA fragments).

tag: ecotype background

tag: genotype/variation

value: 4 weeks

value: flowers


title: cmt2_HiC

tag: developmental stage


title: ddcc_HiC

value: ddcc


title: TP0001651G05_3_0.300000uM_DMEM_6h_TC00283151_C13

description:
TP0001651G05_3_0.300000uM_DMEM_6h
TC00283151_C13

tag: treatment

value: 6h exposure of 0.3 uM of Cyproterone acetate

tag: chemical name

value: Cyproterone acetate


title: suvr2_r2_ATACseq


title: TP0001651A02_5_3.000000uM_DMEM_6h_TC00283151_C12

description:
TP0001651A02_5_3.000000uM_DMEM_6h
TC00283151_C12

value: 6h exposure of 3 uM of Imazalil

value: Imazalil

tag: chemical sample id

value: 3 uM


title: TP0001651B05_6_10.000000uM_DMEM_6h_TC00283151_C11

description:
TP0001651B05_6_10.000000uM_DMEM_6h
TC00283151_C11

value: DMEM + 10% HI-FBS

value: 6h exposure of 10 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride

tag: chemical concentration


title: suvr2_r1_ATACseq


title: nrpe1_r4_ATACseq


title: TP0001651G04_4_1.000000uM_DMEM_6h_TC00283151_C10

description:
TP0001651G04_4_1.000000uM_DMEM_6h
TC00283151_C10

value: 6h exposure of 1 uM of Cladribine

value: Cladribine

value: 1 uM

tag: dose level


title: nrpe1_r3_ATACseq


title: nrpe1_r2_ATACseq


title: nrpe1_r1_ATACseq


title: nrpd1e1_r3_ATACseq


title: TP0001651D02_1_0.030000uM_DMEM_6h_TC00283151_C08

description:
TP0001651D02_1_0.030000uM_DMEM_6h
TC00283151_C08

value: 6h exposure of 0.03 uM of PFOA

value: PFOA

tag: exposure time


title: TP0001651B04_5_3.000000uM_DMEM_6h_TC00283151_C07

description:
TP0001651B04_5_3.000000uM_DMEM_6h
TC00283151_C07

value: 6h exposure of 3 uM of Propiconazole

value: Propiconazole

tag: assay plate


title: TP0001651B01_1_0.030000uM_DMEM_6h_TC00283151_C06

description:
TP0001651B01_1_0.030000uM_DMEM_6h
TC00283151_C06

value: 6h exposure of 0.03 uM of Cyanazine

value: Cyanazine


title: TP0001651D02_2_0.100000uM_DMEM_6h_TC00283151_C04

description:
TP0001651D02_2_0.100000uM_DMEM_6h
TC00283151_C04

value: 6h exposure of 0.1 uM of PFOA


title: TP0001651D02_3_0.300000uM_DMEM_6h_TC00283151_C05

description:
TP0001651D02_3_0.300000uM_DMEM_6h
TC00283151_C05

value: 6h exposure of 0.3 uM of PFOA


title: nrpd1e1_r1_ATACseq

value: 4 weeks

value: flowers


title: nrpd1e1_r2_ATACseq


title: nrpd1_r3_ATACseq


title: TP0001651G05_1_0.030000uM_DMEM_6h_TC00283151_C03

description:
TP0001651G05_1_0.030000uM_DMEM_6h
TC00283151_C03

value: 6h exposure of 0.03 uM of Cyproterone acetate

value: Cyproterone acetate


title: HBRR_TC00283151_C01

description:
HBRR
TC00283151_C01

value: HBRR

value: untreated


title: TP0001651C04_4_1.000000uM_DMEM_6h_TC00283151_C02

description:
TP0001651C04_4_1.000000uM_DMEM_6h
TC00283151_C02

value: DMEM + 10% HI-FBS

value: 6h exposure of 1 uM of Simvastatin

value: Simvastatin


title: nrpd1_r1_ATACseq


title: nrpd1_r2_ATACseq


title: TP0001651G03_7_30.000000uM_DMEM_6h_TC00283151_B23

description:
TP0001651G03_7_30.000000uM_DMEM_6h
TC00283151_B23

value: 6h exposure of 30 uM of Nilutamide

value: Nilutamide

value: 30 uM


title: TP0001651G02_6_10.000000uM_DMEM_6h_TC00283151_B20

description:
TP0001651G02_6_10.000000uM_DMEM_6h
TC00283151_B20

value: 6h exposure of 10 uM of Lovastatin

value: Lovastatin

value: 10 uM


title: idn2idl12_r1_ATACseq


title: met1_r2_ATACseq


title: idn2_r2_ATACseq


title: TP0001651G02_2_0.100000uM_DMEM_6h_TC00283151_B24

description:
TP0001651G02_2_0.100000uM_DMEM_6h
TC00283151_B24

value: 6h exposure of 0.1 uM of Lovastatin


title: TP0001651D01_3_0.300000uM_DMEM_6h_TC00283151_B18

description:
TP0001651D01_3_0.300000uM_DMEM_6h
TC00283151_B18

value: 6h exposure of 0.3 uM of Lactofen

value: Lactofen


title: TP0001651C03_8_100.000000uM_DMEM_6h_TC00283151_B17

description:
TP0001651C03_8_100.000000uM_DMEM_6h
TC00283151_B17

value: 6h exposure of 100 uM of Simazine

value: Simazine


title: idn2idl12_r2_ATACseq

value: 4 weeks

value: flowers


title: TP0001651F05_8_100.000000uM_DMEM_6h_TC00283151_B19

description:
TP0001651F05_8_100.000000uM_DMEM_6h
TC00283151_B19

value: 6h exposure of 100 uM of Fenofibrate

value: Fenofibrate


title: met1_r1_ATACseq


title: 142_039

city: Uppsala

first: Anders

middle: Roger

last: Hedin

state: Uppland

address: Dag Hammarskjölds väg 20.

department: Clinical immunology

country: Sweden

institute: Uppsala University

description: NOTE: Raw data is not included because the files were deleted by the sequencing center.

data_processing:
The raw counts were generated at a separate facility using the Ion AmpliSeq™ Transcriptome Human Gene Expression Kit, the Ion 550™ Kit, and the S5 XL (IonS5XL, Thermo Fisher®) instrument with a 550 chip in 3 separate runs. The primer pool hg19_AmpliSeq_Transcriptome_21K_v1, containing primers for 20,813 amplicons, was used.  The produced reads were aligned to hg19 AmpliSeq Transcriptome ERCC v1. All further analysis was done using the raw counts estimated after mapping.
Two samples(142_021, 142_037, ) produced low quality reads and were excluded from further analysis
The counts from the arterial samples were excluded from further analysis, as they were produced with a different protocol
The transcripts were filtered using the edgeR function "filterbyexpr" with default options and the remaining counts
TMM normalization factors were calculated using "calcnormfactors" in edgeR
TMM- CPM- log2 normalized reads were producted using "cpm(method="TMM, log=TRUE)" in edgeR
Genome_build: Tab- delimited text file with raw counts for each sample that were sequenced
Supplementary_files_format_and_content: comma separated value(CSV) text file with TMM- CPM- log2 normalized counts for each included sample and each transcript that passed

source_name: Normo8 Pancreatic arterial luminal cells

extract_protocol:
Pancreatic islet tissue and pancreatic exocrine tissue was was digested to single cells and endothelial cells were then isolated using FACS. Luminal arterial cells were digested to single cells but not sorted. RNA was extracted.
Libraries were constructed using the Ion AmpliSeq™ Transcriptome Human Gene Expression Kit. RNA seq was then done using the Ion 550™ Kit, and the S5 XL (IonS5XL, Thermo Fisher®) instrument with a 550 chip in 3 separate runs. The primer pool hg19_AmpliSeq_Transcriptome_21K_v1, containing primers for 20,813 amplicons, was used.

value: Cells from luminal arteries in the pancreas

tag: condition

value: Normoglycemic


title: TP0001651F04_1_0.030000uM_DMEM_6h_TC00283151_C09

description:
TP0001651F04_1_0.030000uM_DMEM_6h
TC00283151_C09

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.03 uM of Fulvestrant

value: Fulvestrant

tag: assay plate well


title: TP0001651C04_5_3.000000uM_DMEM_6h_TC00283151_B21

description:
TP0001651C04_5_3.000000uM_DMEM_6h
TC00283151_B21

value: 6h exposure of 3 uM of Simvastatin

value: Simvastatin

value: 3 uM


title: TP0001651F05_4_1.000000uM_DMEM_6h_TC00283151_B22

description:
TP0001651F05_4_1.000000uM_DMEM_6h
TC00283151_B22

value: 6h exposure of 1 uM of Fenofibrate

value: 1 uM


title: idn2_r1_ATACseq


title: 142_037

source_name: Normo8 Pancreatic islet MVEC(Microvascular Endothelial Cells)

value: FACS sorted endothelial cells from pancreatic Islet


title: nrpd1_r4_ATACseq


title: TP0001651D02_5_3.000000uM_DMEM_6h_TC00283151_B16

description:
TP0001651D02_5_3.000000uM_DMEM_6h
TC00283151_B16

value: 6h exposure of 3 uM of PFOA

value: PFOA


title: 142_035

source_name: IGM5 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)

value: FACS sorted endothelial cells from exocrine pancretic tissue

value: IGM(Impaired glucose metabolism)


title: drm3_r1_ATACseq

value: 4 weeks

value: flowers


title: frg12_r1_ATACseq


title: 142_038

source_name: Normo8 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)


title: 142_036

source_name: IGM5 Pancreatic arterial luminal cells

value: Cells from luminal arteries in the pancreas


title: TP0001651A05_4_1.000000uM_DMEM_6h_TC00283151_B14

description:
TP0001651A05_4_1.000000uM_DMEM_6h
TC00283151_B14

value: 6h exposure of 1 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651C04_3_0.300000uM_DMEM_6h_TC00283151_B15

description:
TP0001651C04_3_0.300000uM_DMEM_6h
TC00283151_B15

value: DMEM + 10% HI-FBS

value: 6h exposure of 0.3 uM of Simvastatin


title: drm3_r2_ATACseq


title: TP0001651E05_6_10.000000uM_DMEM_6h_TC00283151_B12

description:
TP0001651E05_6_10.000000uM_DMEM_6h
TC00283151_B12

value: 6h exposure of 10 uM of Atrazine

value: Atrazine

value: 10 uM


title: frg12_r2_ATACseq


title: 142_033

source_name: IGM4 Pancreatic arterial luminal cells


title: 142_032

source_name: IGM4 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)


title: 142_029

source_name: Normo7 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)

value: Normoglycemic


title: TP0001651D01_6_10.000000uM_DMEM_6h_TC00283151_B11

description:
TP0001651D01_6_10.000000uM_DMEM_6h
TC00283151_B11

source_name: MCF7 Cells

value: 6h exposure of 10 uM of Lactofen

value: Lactofen


title: 142_034

source_name: IGM5 Pancreatic islet MVEC(Microvascular Endothelial Cells)

value: FACS sorted endothelial cells from pancreatic Islet


title: 142_031

source_name: IGM4 Pancreatic islet MVEC(Microvascular Endothelial Cells)


title: dms3_r2_ATACseq


title: 142_030

source_name: Normo7  Pancreatic arterial luminal cells


title: TP0001651G03_5_3.000000uM_DMEM_6h_TC00283151_B09

description:
TP0001651G03_5_3.000000uM_DMEM_6h
TC00283151_B09

value: 6h exposure of 3 uM of Nilutamide

value: Nilutamide

value: 3 uM


title: ddm1_r2_ATACseq

value: 4 weeks


title: drm12_r1_ATACseq

value: flowers


title: 142_027

source_name: IGM3 Pancreatic arterial luminal cells

value: Cells from luminal arteries in the pancreas

value: IGM(Impaired glucose metabolism)


title: dms3_r1_ATACseq


title: TP0001651H03_8_100.000000uM_DMEM_6h_TC00283151_B13

description:
TP0001651H03_8_100.000000uM_DMEM_6h
TC00283151_B13

value: 6h exposure of 100 uM of Fomesafen

value: Fomesafen


title: 142_026

source_name: IGM3 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)

value: FACS sorted endothelial cells from exocrine pancretic tissue


title: ddm1_r1_ATACseq


title: TP0001651H03_4_1.000000uM_DMEM_6h_TC00283151_B06

description:
TP0001651H03_4_1.000000uM_DMEM_6h
TC00283151_B06

value: DMEM + 10% HI-FBS

value: 6h exposure of 1 uM of Fomesafen

value: 1 uM


title: TP0001651D03_6_10.000000uM_DMEM_6h_TC00283151_B10

description:
TP0001651D03_6_10.000000uM_DMEM_6h
TC00283151_B10

value: 6h exposure of 10 uM of Cypermethrin

value: Cypermethrin

value: 10 uM


title: TP0001651H04_2_0.100000uM_DMEM_6h_TC00283151_B08

description:
TP0001651H04_2_0.100000uM_DMEM_6h
TC00283151_B08

value: 6h exposure of 0.1 uM of Bisphenol A

value: Bisphenol A


title: 142_025

source_name: IGM3 Pancreatic islet MVEC(Microvascular Endothelial Cells)

value: FACS sorted endothelial cells from pancreatic Islet


title: drm12_r2_ATACseq


title: 142_028

source_name: Normo7 Pancreatic islet MVEC(Microvascular Endothelial Cells)

value: Normoglycemic


title: 142_024

source_name: Normo6 Pancreatic arterial luminal cells


title: 142_020

source_name: Normo5 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)


title: TP0001651D05_6_10.000000uM_DMEM_6h_TC00283151_B07

description:
TP0001651D05_6_10.000000uM_DMEM_6h
TC00283151_B07

value: 6h exposure of 10 uM of Thiram

value: Thiram


title: 142_021

source_name: Normo5 Pancreatic arterial luminal cells

value: Cells from luminal arteries in the pancreas


title: 142_022

source_name: Normo6 Pancreatic islet MVEC(Microvascular Endothelial Cells)


title: 142_023

source_name: Normo6 Pancreatic exocrine MVEC(Microvascular Endothelial Cells)


title: ddcc_r1_ATACseq

value: ddcc

value: 4 weeks

value: flowers


title: 142_019

source_name: Normo5 Pancreatic islet MVEC(Microvascular Endothelial Cells)


title: ddcc_r2_ATACseq


title: TP0001651A04_1_0.030000uM_DMEM_6h_TC00283151_B05

description:
TP0001651A04_1_0.030000uM_DMEM_6h
TC00283151_B05

value: 6h exposure of 0.03 uM of Rotenone

value: Rotenone


title: col_r4_ATACseq

value: wild type


title: TP0001651A02_8_100.000000uM_DMEM_6h_TC00283151_B04

description:
TP0001651A02_8_100.000000uM_DMEM_6h
TC00283151_B04

value: DMEM + 10% HI-FBS

value: 6h exposure of 100 uM of Imazalil

value: Imazalil


title: 142_018

description: NOTE: Raw data is not included because the files were deleted by the sequencing center.

source_name: Normo4 Pancreatic arterial luminal cells


title: col_r3_ATACseq