title: E_cho_4_09

data_processing:
Sequencing reads were aligned to the Homo sapiens reference genome (hg38) with TopHat (v2.1.0).
HTSeq (v0.6.0) was used to quantify the reads that mapped to each gene.
Gene expression levels were evaluated as transcripts per million (TPM).
Genome_build: hg38 (GRCh38)
Supplementary_files_format_and_content: SmartSeq2.ReadCount.txt: Tab-delimited text file includes read count values for each sample.
Supplementary_files_format_and_content: SmartSeq2.TPM.txt: Tab-delimited text file includes TPM values for each sample.

source_name: EnSC

growth_protocol: Human endoderm stem cells were generated from hPSCs and maintained in serum-free conditions as described previously (Cheng et al., 2012). For the hepatocyte differentiation, the EnSCs were dissociated into a single-cell suspension with 0.25% trypsin-EDTA, and then the cells were suspended in a 500 mL spinner flask at a density of 1×10e6 cells per milliliter in 300 mL hepatic specification medium, mixed with Matrigel at the final concentration of 4%, that contained ascorbic acid (Wako), MTG (Sigma), bFGF (10 ng/ml), TGF-α (20 ng/ml), EGF (10 ng/ml), VEGF (10 ng/ml), BMP4 (50 ng/ml), HGF (25 ng/ml), dexamethasone (Dex) (40 ng/ml, Sigma), and 1% DMSO (Sigma) (from day 0 to day 6, Stage I). From day 6 to day 12 (Stage II), the medium was replaced with hepatoblast formation medium containing ascorbic acid, MTG, bFGF (10 ng/ml), HGF (25 ng/ml), EGF (20 ng/ml), VEGF (10 ng/ml), oncostatin M (OSM) (20 ng/ml), Dex (40 ng/ml), 1% DMSO, Compound E (0.1 μM, Millipore), A83-01 (0.5 μM, Selleck), and Vitamin K1 (6 g/ml, Sangon). Then, the medium was changed to maturation medium, which contained ascorbic acid, MTG, HGF (25 ng/ml), OSM (20 ng/ml, PeproTech), Dex (40 ng/ml), Compound E (0.1 μM), A83-01 (0.5 μM), Vitamin K1 (6 g/ml), and erlotinib HCl (EGFi) (2 μM, Stemgent) (from day 12 to day 24, Stage 3H). The above differentiation medium was SFD-based (Cheng et al., 2012). From day 24, the hepatic spheres were cultured in hepatocyte culture medium (HCM, Lonza) that consisted of ascorbic acid, MTG, 8 bromo-cAMP (1 mM, Biolog), Compound E (0.1 μM), A83-01 (0.5 μM), Vitamin K1 (6 g/ml), and EGFi (2 μM) (from day 24 to day 30, Stage 4H). The medium was changed every 2 days. The cells were maintained in a 5% CO2, 5% O2, 90% N2 environment (from day 0 to day 18), and then in a 5% CO2/ambient air environment (from day 18 to day 30). The hepatic spheres were stirred at the optimal speed of 60 rpm. All cytokines were human and purchased from R&D Systems, unless stated otherwise. For the cholangiocyte differentiation, the hepatoblasts were generated from EnSCs using the method as aforementioned. After hepatoblast formation, the hepatic spheres were cultured in SFD-based cholangiocyte specification medium containing ascorbic acid, MTG, FGF10 (50 ng/ml), Activin A (50 ng/ml), and retinoic acid (3 μM, Sigma) (from day 12 to day 15, Stage 3C). Then, the medium was changed to maturation medium, which contained HGF (25 ng/ml), EGF (50 ng/ml), TGF-β (5 ng/ml, PeproTech), Dex (40 ng/ml), and TPPB (0.5 μM, Calbiochem) (from day 16 to day 21, Stage 4C). The basic medium used for this final stage was biliary differentiation medium (BDM) (Sampaziotis et al., 2015). The cells were cultured in a 5% CO2, 5% O2, 90% N2 environment. The hepatic spheres were stirred at the optimal speed of 60 rpm. All cytokines were human and purchased from R&D Systems, unless stated otherwise.

value: EnSC-derived cholangiocyte


title: E_cho_4_08

status: Public on Apr 20 2021

type: SRA

city: Beijing

first: Cheng-ran

last: Xu

address: NO.5 YIHEYUAN ROAD HAIDIAN DISTRICT, BEIJING, P.R.CHINA

department: School of Basic Medical Sciences

country: China

institute: Peking University

library_source: transcriptomic

molecule: total RNA

organism: Homo sapiens

extract_protocol:
Single-cell RNA-seq was performed according to the Smart-seq2 protocol as reported previously (Picelli et al., 2014). After the cells were digested into a single-cell suspension, each single-cell sample was manually selected under a microscope with a mouth pipette and transferred into lysis buffer containing 1.9 µl of 0.2% Triton X-100 (Sigma), 1 µl of 10 µM oligo (dT) primer, 1 µl of 10 mM dNTP mix (New England Biolabs), 0.1 µl of 40 U/µl RNase inhibitor (New England Biolabs) and 0.05 µl of ERCC spike-in RNA (a dilution of 1:300,000, Life Technologies). After single-cell lysis, the sample was mixed with 0.29 µl H2O, 2 µl of 5× Superscript II first-strand buffer, 2 µl of 5 M Betaine (Sigma), 0.5 µl of 100 mM DTT, 0.06 µl of 1 M MgCl2, 0.1 µl of 100 µM TSO primer, 0.25 µl of 40 U/µl RNase inhibitor and 0.5 µl of 200 U/µl SuperScript II reverse transcriptase (Invitrogen). After reverse transcription was performed, 2.25 µl H2O, 12.5 µl KAPA HiFi HotStart ReadyMix (KAPA Biosystems) and 0.25 µl of 10 µM IS PCR primer were added to the sample. Then, PCR preamplification was conducted for 18 cycles. Next, cDNA samples were purified with VAHTS DNA Clean Beads XP beads (Vazyme).
Purified cDNA (2 ng) was prepared for library construction using a TruePrep DNA Library Prep Kit (Vazyme) with a 0.4× standard reaction system, and PCR amplification was conducted for 8 cycles. Finally, the library was purified and size-selected, and fragments with a peak size of ~350 bp were analyzed with an Advanced Analytical Fragment Analyzer.

tag: cell type


title: E_cho_4_10


title: Day 90 Organoids colonic Mock 4DPI Rep 2

city: Boston

first: Carlos

last: Villacorta-Martin

state: MA

address: 670 Albany St

country: USA

institute: Center for Regenerative Medicine at Boston University

data_processing:
Sequencing of pooled libraries were done using NextSeq 500 (Illumina). The quality of the raw data was assessed using FastQC v.0.11.7. Sequence reads were aligned to a combination of the human genome reference (GRCh38) and SARS-CoV-2 sequence, using STAR v.2.6.0c. Counts per gene were summarized using the featureCounts function from the subread package v.1.6.2.
Ensembl v67 gene annotations were used for gene counts, gene counts were obtain using STAR v2.6
Raw gene counts were normalized using limma/voom method
Genome_build: GRCh38 with SARS_CoV2 genome and tdtomato
Supplementary_files_format_and_content: Matrix of counts per million reads per sample

molecule: polyA RNA

source_name: BU1CG human iPSC

growth_protocol: To derive proximal and colonic intestinal epithelial cells/organoids, PSCs were first dissociated into single cells suspension and 1.8-2X106 cells were plated per well (triplicate wells, n=3) of a 6-well tissue culture plate coated with Matrigel for 24 hours in mTeSR media containing ROCK inhibitor (RI) prior to differentiation into definitive endoderm differentiation using the Definitive Endoderm Kit (Stem Cell Technologies, 05110) for 3 days (day 0-3). To drive further maturation of definitive endoderm, day 3 cells were then passed 1:3-1:6 to a new plate in complete serum free differentiation medium (cSFDM) described in Gouon-Evans et al. (2006) supplemented with 2mM of dorsomorphin (DS, Stemgent, 040024) and 10mM SB431543 (SB, Biotechne, 1614) (together constituting DS/SB media) for 3 days (day 3-6) plus 10mM RI for the first 24 hrs. On day 6, cells were re-fed with cSFDM media supplemented with 3mM CHIR (Biotechne, 4423) 100nM retinoic acid (Sigma-Aldrich, R2625), and 10ng/mL rhBMP4 (BioTechne, 314BP) for specification of intestinal lineages. On day 15, cells were single-cell dissociated by trypsin for fluorescence activated cell sorting a CDX2-eGFP reporter (BU1CG, Mithal et al 2020). Cells were then cultured in three dimensional matrigel droplets, either CK+DCI (colon) or IM+CK (intestinal) to regionally pattern HIOs.

extract_protocol:
Following cell sorting for desired cell population, biological triplicate (n=3) samples of purified RNA was harvested using Qiazol and RNA Sample Preparation Kit v2 (QIAGEN).
Total mRNA was isolated using magnetic beads-based poly(A) selection, fragmented, and randomly fragmented for reverse transcription, followed by synthesis of cDNA fragments. cDNA fragments were then end-paired, and ligated to Illumina Paired-End sequencing adapters. The products were end-paired and PCR-amplified to create the final cDNA library.

treatment_protocol: After maturation of HIOs, HIOs were infected with purified SARS-CoV-2 stock at MOI 0.4. 100 μl inoculum was prepared in CK+DCI or IM+CK media for colonic or proximal HIOs, respectively (or mock-infected with medium-only). To facilitate infection, HIOs were isolated from matrigel.  Briefly, media was removed from wells containing HIOs, 0.5 mL Cell Recovery Solution (Corning) was added to the cells in matrigel, and plates were incubated at 4oC for 30 minutes.  The dissolved matrigel and cells in the Cell Recovery Solution were then transferred to 2 mL Sarstedt tubes .  Cells were pelleted by low speed centrifugation (300xg, 5 minutes).  Supernatant was removed and virus-free or virus-containing media were added to the corresponding tubes.  Cell pellets were mechanically disrupted to facilitate viral access.  HIOs were then incubated for 1 hour at 37oC and 5% CO2.  After the adsorption period, cells were pelleted by low speed centrifugation (300xg, 5 minutes) and the inoculum was removed.  Cells were subsequently re-plated in matrigel droplets with media and incubated at 37oC for the indicated times of infection. After 1 and 4 dpi, cells were lysed in Trizol and removed from the BSL4 lab, where RNA extraction was performed as per manufacterers recommended protocols

tag: developmental stage

value: Day 90 colonic organoid directed differentiation

tag: culture media

value: CK+DCI

tag: treatment

value: Mock

tag: days post treatment

tag: isolation method

value: whole organoids


title: E_cho_4_06


title: E_cho_4_11


title: Day 90 organoids Colonic SARS 1DPI Rep 1

value: SARS-CoV-2 infected


title: Day 90 organoids Colonic SARS 1DPI Rep 2


title: E_cho_4_07


title: E_cho_4_05


title: E15_FJW161014001_D08

city: Chuo-ku, Kobe

first: Hironobu

last: Fujiwara

address: 2-2-3 Minatojima-minamimachi

department: Center for Biosystems Dynamics Research

country: Japan

institute: RIKEN

description: EWF-E15_FJW161014001_D08_ACTGAGC-ACTGCAT_L006

data_processing:
FASTQ files were generated using bcl2fastq (v1.0) for NextSeq.
fastq-mcf (version 1.04.807) was used for adapter trimming with the parameters '-L 42 -l 36 -k 4.0 -q 30' for HiSeq 1500, '-L 50 -l 36 -k 4.0 -q 30' for HiSeq 2500 and '-L 75 -l 36 -k 4.0 -q 30' for NextSeq. The reads were mapped to the mouse genome (mm10) using HISAT2 (version 2.0.4) with the parameters '-p 4 --end-to-end'. Transcript levels were quantified as Transcripts Per Kilobase Million (TPM) with Sailfish (version 0.10.0) using GENCODE vM14 annotation file.
outside of the mean minus three standard deviations of the number of mapped reads to a sailfish index (Sailfish) or the number of assigned reads to gene regions (featureCounts, function of Subread version 1.5.0); over 10% reads assigning to mitochondrial RNA (featureCounts); abnormal gene body coverage of sequencing reads by human curation (RseQC, version 2.6.4).
for count table, after convert Ensemble transcript_id to Gene_id, each isoform expression were summarized on gene level.
Genome_build: mm10
Supplementary_files_format_and_content: txt

organism: Mus musculus

source_name: E15.0_whisker follicles cells

extract_protocol:
Single cells were directly sorted into the cell lysis buffer containing RNasein plus (Promega), Cell Lysis Buffer (Roche), NP40 (Thermo), and RNase free water (TaKaRa).
RamDA-seq sequencing libraries were prepared by using the advanced method of RamDA-seq (refer to the Methods section in "Single-cell full-length total RNA sequencing uncovers dynamics of non-polyadenylated RNAs, recursive splicing and enhancer RNAs" DOI: https://doi.org/10.1038/s41467-018-02866-0).

tag: Stage

value: whisker follicles cells

tag: data quality

value: ok


title: E15_FJW161014001_E01

description: EWF-E15_FJW161014001_E01_ACTCGCT-AAGGAGT_L006


title: E_cho_4_04


title: Day 90 organoids Colonic Mock 1DPI Rep 3


title: E15_FJW161014001_D06

description: EWF-E15_FJW161014001_D06_ATGCGCA-ACTGCAT_L006


title: E15_FJW161014001_D07

description: EWF-E15_FJW161014001_D07_TAGCGCT-ACTGCAT_L006


title: Day 90 Organoids colonic Mock 1DPI Rep 2


title: E15_FJW161014001_D05

description: EWF-E15_FJW161014001_D05_TACGCTG-ACTGCAT_L006


title: E15_FJW161014001_D04

description: EWF-E15_FJW161014001_D04_CGGAGCC-ACTGCAT_L006


title: E_cho_4_03


title: E_cho_4_02


title: Day 90 organoids Colonic Mock 1DPI Rep 1


title: E15_FJW161014001_D02

description: EWF-E15_FJW161014001_D02_GGAGCTA-ACTGCAT_L006


title: E15_FJW161014001_D03

description: EWF-E15_FJW161014001_D03_GCGTAGT-ACTGCAT_L006


title: E_cho_4_01


title: CSB-KO_UV_20J8h

city: Leiden

first: Martijn

middle: S.

last: Luijsterburg

state: zuid-holland

address: Einthovenweg 20

department: Human Genetics

country: Netherlands

institute: LUMC

description:
genomic DNA (ChIP)
genome used for mapping:
Hg38

library_source: genomic

data_processing:
ChIP-seq, BrU-seq and ATAC-seq data analyses: For RNAPII-Ser2 ChIP-seq, low-quality sequence reads and adapters were filtered out by Trimmomatic (v3.36) (A. M. Bolger et al, 2014). The trimmed reads were aligned to the human reference genome (GRC h37/hg19) with the Burrows-Wheeler Aligner (BWA-v0.7.12-r1039) (H. Li et al, 2013). Biobambam2 (v2.0.72) (G. Tischler et al, 2014) was used to remove duplicate reads from the aligned reads. Sequence reads were locally realigned and base-quality scores were recalibrated with the IndelRealigner and BaseRecalibrator programs in Genome Analysis Toolkit (GATK-v3.5) (McKenna et al, 2010).
For pan-RNAPII ChIP-seq, BrU-seq and ATAC-seq, reads were aligned to the Human Genome 38 (Hg38) using bwa-mem tools (BWA (Version 0.7.16a) or STAR (Version 2.5.3a)) (H. Li et al, 2013; Dobin et al, 2013). Only high-quality reads (> q30) were included in the analyses and duplicates were removed using Samtools (Version 1.6) with fixmate -m and markdup -r settings (Table S7). Bam files were converted into stranded TagDirectories and UCSC genome tracks using HOMER tools (Version 4.8.2) (S. Heinz et al, 2010). A list of 49,948 genes was obtained from the UCSC genome database (https://genome.ucsc.edu/cgi-bin/hgTables) selecting the knownCanonical table containing the canonical transcription start sites per gene. To prevent contamination of binding profiles, genes should be non-overlapping with at least 2 kb between genes. Subsequent selection of sets of genes is described per analysis.
For ChIP-seq, binding profiles within selected areas of individual genes (e.g. around TSS or TTS), were defined using the AnnotatePeaks.pl tool of HOMER using the default normalization to 10mln reads. Metagene profiles were defined using the makeMetaGeneProfile.pl tool of HOMER, using default settings. Read densities in input samples were subtracted from individual ChIP-seq datasets to background-correct our data in which negative values were converted to 0, to prevent the use of impossible negative read densities in further calculations. Individual datasets were subsequently processed into heatmaps or binding profiles using R (Version 3.5.3) (R. Core Team, R, 2019). ChIP-seq binding and metagene profiles were averaged per set of genes and profiles were normalized to area under the curve to allow proper comparison of the profiles without effects of overall differences in read density.
ATAC-seq and BrU-seq heatmaps were generated as described for ChIP-seq analyses, except for the input subtraction and removal of negative values. BrU-seq aggregated profiles, were defined using the AnnotatePeaks.pl tool or makeMetaGeneProfile.pl tool of HOMER using the default normalization to 10mln reads, as for ChIP-sequencing. Genes were selected on size and strongest binding of RNAPII at the TSS in undamaged condition, as for ChIP-sequencing. Averaged binding profiles were subsequently normalized to nascent transcript levels, as quantified by 5-EU labelling, relative to the control in their specific cell type. For example, WT cells 3 h after UV irradiation showed 35% RNA relative to WT control cells, so we multiplied the expression of the bins by 0.35.  RNA-seq analyses: Obtained sequencing reads were cleaned by 5'-end quality trimming and Illumina-adapter clipping by Trimmomatic (A. M. Bolger et al, 2014). Pre-alignment quality control of the cleaned sequencing reads was done with FastQC. The alignment to reference genome hg19 of trimmed sequencing reads was done with Hisat2, guided by gene annotation in the refGene UCSC table (D. Kim et al, 2015). The generated SAM files were converted to the binary counterpart BAM, followed by BAM sorting and indexing with SAMtools (H. Li et al, 2009).  Counting reads to the UCSC's genomic features hg19 was performed by Subread/featureCounts (Y. Liao et al, 2014). Differential expression analysis was carried out, using edgeR (M. D. Robinson et al, 2010). Only genes indicating at least 2 counts per million in at least 20% of samples were included in the analysis. Data were normalized for sample specific effects by the trimmed mean of M-values. This was followed by estimating the dispersion and determining the differentially expressed genes using the general linear model (GLM). FDR-adjusted p-values < 0.05 were considered significant.
Genome_build: hg19 or hg38 as indicated per sample
Supplementary_files_format_and_content: excel tables providing stranded metagene profiles for the top 3000 genes for each individual sample, and the BrU-seq counts versus distance from the TSS for genes of 25-50Kb, 50-100Kb and >100Kb

molecule: genomic DNA

source_name: U2OS CSB-KO

growth_protocol: DMEM GlutaMAX +10% Fetal Calf Serum + antibiotics

extract_protocol:
ATAC-seq: For each experimental condition 50.000 cells were harvested and washed with cold PBS containing protease inhibitors (Roche). The cells were resuspended in 50  l Transposase mixture, containing 1x Tagment DNA buffer Illumina Kit, #20034197), 0.5  l Tagment DNA enzyme (Illumina Kit, #20034197) and 0,2  g/ l Digitonin (Promega, #G9441), and incubated at 37  C for 30 min. Fragmented DNA was purified using a Qiagen MinElute kit (#28204).  BrU-seq: For BrU(DRB)-seq, cells were pre-treated with 100  M DRB for 1-3hrs (as indicated per sample) after which cells were washed with PBS and immdeidately, or 30 min later, incubated with 2 mM bromouridine (Bru) at 37 C for 15 or 30 min. For regular BrU-seq, cells were either mock-treated or irradiated with UV-C light (9 J/m2). Cells were then incubated in conditioned media for different periods of time before being incubated with 2 mM bromouridine (Bru) at 37 C for a 30 min. The cells were then lysed in TRIzol reagent (Invitrogen) and Bru-containing RNA isolated as previously described (Andrade-Lima et al., 2015). ChIP-seq: Cells were mock treated or UV-irradiated with 9 J/m2 and incubated in conditioned media for different periods of time (1, 4, 8, 16 h). Cells were crosslinked with 0.5 mg/mL disuccinimidyl glutarate (DSG; Thermo Fisher) in PBS for 45 min at room temperature. Cells were washed with PBS and crosslinked with 1% PFA for 20 min at room temperature. Fixation was stopped by adding 1.25 M Glycin in PBS to a final concentration of 0.1 M for 3 minutes at room temperature. Cells were washed with cold PBS and lysed and collected in a buffer containing 0.25% Triton X-100, 10 mM EDTA (pH 8.0), 0.5 mM EGTA (pH 8.0) and 20 mM Hepes (pH 7.6). Chromatin was pelleted in 5 min at 400 g and incubated in a buffer containing 150 mM NaCl, 1 mM EDTA (pH 8.0), 0.5 mM EGTA (pH 8.0) and 50 mM Hepes (pH 7.6) for 10 minutes at 4 C. Chromatin was again pelleted for 5 min at 400 g and resuspended in ChIP-buffer (0.15 % SDS, 1 % Triton X-100, 150 mM NaCl, 1 mM EDTA (pH 8.0), 0.5 mM EGTA (pH 8.0) and 20 mM Hepes (pH 7.6)) to a final concentration of 15x106 cells/ml. Chromatin was sonicated to approximately 1 nucleosome using a Bioruptor waterbath sonicator (Diagenode). Chromatin of ~5x106 cells was incubated with 3  g antibody (Antibodies are listed in Table S3) overnight at 4 C, followed by a 1.5 h protein-chromatin pull-down with a 1:1 mix of protein A and protein G Dynabeads (Thermo Fisher; 10001D and 10003D). ChIP samples were washed extensively, followed by decrosslinking for 4 h at 65 C in the presence of proteinase K. DNA was purified using a Qiagen MinElute kit.  RNA-seq: Cells were UV-irradiated (254 nm, 9 J/m2) or mock-treated and harvested 24 h later. Total RNA was isolated using the RNeasy mini kit (Qiagen) according to the manufacturer's protocol. Up to 5   106 cells per sample were lysed in RLT buffer. For quantification purposes, 24 ng of the eight ArrayControl(tm) RNA Spikes (Thermo Fisher Scientific) were added to each sample (3 ng/spike).
ATAC-seq: Libraries were prepared by PCR using NEBNext High-Fidelity 2x PCR Master Mix (New England Labs, #M0541) and Nextera XT index Kit v2 (Illumina). Samples were sequenced on an Illumina HiSeq X system (Macrogen), resulting in 150 bp paired-end reads. BrU-seq: cDNA libraries were made from the Bru-labeled RNA using the Illumina TruSeq library kit and paired-end 151 bp sequenced using the Illumina NovaSeq platform at the University of Michigan Advanced Genomics Core. Indicated is whether single-end or paired-end sequencing data was used for downstream analyses ChIP-seq: For RNAPII-Ser2 ChIP-seq sample libraries were prepared from 1 ng ChIPed DNA using NEBNext Ultra II DNA Library Prep Kit for Illumina (NEB, E7645S) and index primer sets (NEB, E7335S). Strand-biased library amplification was performed using high-fidelity KAPA HiFi Enzyme (Roche, KK2102). The prepared libraries were sequenced on an Illumina HiSeq 2500 system (Illumina), resulting in 150 bp paired-end reads. For the remaining ChIP-seq samples, libraries were prepared using kapa hyper prep kit (Roche) and A-T mediated ligation of full Y-shaped IDT adapters. Samples were sequenced on an Illumina HiSeq X system (Macrogen), resulting in 150 bp paired-end reads. RNA-seq: Samples were purified using the KAPA mRNA Hyperprep kit (Roche) and prepared for sequencing using the TruSeq RNA Library Prep Kit v2 (Illumina) according to the manufacturer's instructions, and sequenced in a single lane on an Illumina HiSeq4000.

treatment_protocol: DNA damage was induced by irradiating cells with varying doses of UV-C as indicated per sample; samples were assayed at different time-periods after UV treatment as indicated per sample.

tag: cell line

tag: genotype

value: CSB-KO

tag: uv-c dose

tag: time after uv-c

value: 8 hours

tag: chip-antibody

value: Pan-RNAPII (Bethyl; A304-405A)


title: E15_FJW161014001_C12

description: EWF-E15_FJW161014001_C12_TCGACGT-GTAAGGA_L006


title: E15_FJW161014001_C10

description: EWF-E15_FJW161014001_C10_CGATCAG-GTAAGGA_L006


title: E_cho_3_26


title: CSB-KO_UV_6J8h_2


title: E_cho_3_25


title: E15_FJW161014001_C09

description: EWF-E15_FJW161014001_C09_CCTAAGA-GTAAGGA_L006


title: CSB-KO_mock_2

value: mock

value: not applicable


title: E15_FJW161014001_C07

description: EWF-E15_FJW161014001_C07_TAGCGCT-GTAAGGA_L006


title: E15_FJW161014001_C08

description: EWF-E15_FJW161014001_C08_ACTGAGC-GTAAGGA_L006


title: CSB-KO_mock_1


title: SUMO-KO 3 [431_12]

city: Jupiter, FL 33458

first: Gogce

middle: Ceren

last: Crynen

state: Florida

address: 130 Scripps Way

department: Bioinformatics and Statistics Core

institute: UF Scripps Biomedical Research

data_processing:
We used an Illumina NextSeq 500 system and a HIGH output 75 Kit with 2x40 bp read length. Base-calling was performed online during the sequencing procedure with the Real-Time Analysis (RTA) software version 2.4.11 and System Suite Version 2.2.0.
RNAseq reads were trimmed using cutadapt version 2.10 with the following parameters : -a AGATCGGAAGAGCACACGTCTGAACTCCAGTCA -A AGATCGGAAGAGCGTCGTGTAGGGAAAGAGTGT --minimum-length=15 –pair-filter=any.
Reads were mapped to the mouse genome using STAR version 2.5.2a. Bowtie v1.1.2 was used to identify any reads mapping to rRNA and tRNA were filtered out ( M.musculus-UCSC-mm10).
Reads were aligned to the mouse transcriptome with STAR version 2.5.2a using the mouse-ENSEMBL-grcm38.r91 genome annotation.
Differential gene expression analysis was performed using Deseq2.
Genome_build: mm10
Supplementary_files_format_and_content: comma-separated file includes the gene count data for all samples

source_name: SUMO-KO_Striatal cells

extract_protocol:
Total RNAs of these samples were isolated using miRNeasy Mini Kit (Qiagen)
NEBNext Ultra II directional library prep with rRNA-depletion module

tag: strain background

tag: genotype/variation

value: SUMO-1 KO mouse

value: Striatal cells


title: E15_FJW161014001_C06

description: EWF-E15_FJW161014001_C06_ATGCGCA-GTAAGGA_L006


title: SUMO-KO 2 [431_11]


title: E15_FJW161014001_C04

description: EWF-E15_FJW161014001_C04_CGGAGCC-GTAAGGA_L006


title: E15_FJW161014001_C05

description: EWF-E15_FJW161014001_C05_TACGCTG-GTAAGGA_L006


title: E15_FJW161014001_H07

description: EWF-E15_FJW161014001_H07_TAGCGCT-TCTCTCC_L006


title: E15_FJW161014001_D01

description: EWF-E15_FJW161014001_D01_ACTCGCT-ACTGCAT_L006


title: E15_FJW161014001_C02

description: EWF-E15_FJW161014001_C02_GGAGCTA-GTAAGGA_L006


title: E15_FJW161014001_B12

description: EWF-E15_FJW161014001_B12_TCGACGT-TATCCTC_L006


title: E15_FJW161014001_C01

description: EWF-E15_FJW161014001_C01_ACTCGCT-GTAAGGA_L006


title: E15_FJW161014001_C03

description: EWF-E15_FJW161014001_C03_GCGTAGT-GTAAGGA_L006


title: SUMO-KO 1 [431_10]


title: Q175HD/SUMO-KO 3 [431_13]

source_name: Q175HD/SUMO-KO_Striatal cells

value: SUMO-1 KO in the Q175 neo-deleted knockin mouse


title: HeLa cells, siCtrl rep_2

city: Aveiro

first: Ana

last: Soares

address: Campus de Santiago

country: Portugal

institute: University of Aveiro

data_processing:
Image analysis and base calling were performed using Solexa pipeline v1.8 (Off-Line Base Caller software, v1.8).
Sequencing quality was examined by FastQC and trimmed reads (pass Illumina quality  filter, trimmed 5’,3’-adaptor bases by cutadapt) were aligned allowing for 1 mismatch only to the  mature tRNA sequences, then reads that did not map were aligned allowing for 1 mismatch only to precursor  tRNA sequences with bowtie software.
The abundance of tRF & tiRNA was evaluated using their sequencing counts and was normalized as counts per million of total aligned reads  (CPM). The tRFs & tiRNAs differentially expressed were screened based on the count value  with R package edgeR.
Principal Component Analysis (PCA), Correlation Analysis, Pie plots, Venn  plots, Hierarchical clustering, Scatter plots and Volcano plots were performed in R or perl environment for  statistical computing and graphics of the expressed tRF & tiRNA.
Genome_build: GtRNAdb
Supplementary_files_format_and_content: Excel files containing tRF and tiRNA ID, sequence, type, length of sequence, alignment information, read count and CPM, the counts of per million mapped reads:
[Expression]  contains all the expressed tRFs and tiRNAs sequenced in all samples
[Up_siTRMT2A vs siCtrl]  contains tRFs and tiRNAs upregulated in the siTRMT2A condition
[Down_siTRMT2A vs siCtrl]  contains tRFs and tiRNAs downregulated in the siTRMT2A condition

source_name: HeLa cells

growth_protocol: HeLa cells were cultured in Dulbecco’s Modified Eagle Medium (DMEM) (Gibco, Cat.11965084), supplemented with 10% of Fetal Bovine Serum (FBS) (Sigma, Cat.F1051) and 1% of Pen-Strep-Glut (Gibco, Cat.15070063). Cells were maintained in culture in an incubator at 37°C with 5% of CO2 and 95% of humidity.

extract_protocol:
The total RNA was extracted using the mirVanaTM miRNA Isolation kit (Ambion) or TRIsure™ (Bioline) according to manufacturer´s instructions. The integrity and quantity of each RNA sample were assessed using a Bioanalyzer.
Total RNA samples were first pretreated as following to remove some  RNA modifications that interfere with small RNA-seq library construction: 3’-aminoacyl (charged)  deacylation to 3’-OH for 3’-adaptor ligation, 3’-cP (2’,3’-cyclic phosphate) removal to 3’-OH for 3’  -adaptor ligation, 5’-OH (hydroxyl group) phosphorylation to 5’-P for 5’-adaptor ligation, m1A and  m3C demethylation for efficient reverse transcription. Then pretreated total RNA was used to prepare  the sequencing library in the following steps: 1) 3’-adapter ligation; 2) 5’-adapter ligation; 3) cDNA  synthesis; 4) PCR amplification; 5) size selection of 134_x0018_160bp PCR amplified fragments (corresponding  to 14_x0018_40nt small RNA size range). The libraries were denatured as single-stranded DNA molecules,  captured on Illumina flow cells, amplified in situ as sequencing clusters and sequenced for 50 cycles on  Illumina NextSeq 500 system per the manufacturer’s instructions.
Small-RNA Seq

treatment_protocol: A siGenome SMARTpool human siRNA targeting the tRNA-modifying enzyme TRMT2A (siTRMT2A) and a negative control siGenome SMARTpoll human siRNA (siCtrl) were obtained from Dharmacon (ThermoScientific) and reversely transfected into HeLa cells in 24 well plates. SMARTpools are a mixture of 4 siRNAs against the gene of interest provided as a single reagent, increasing potency and specificity. Briefly, 12 µL of 500 nM siRNA duplex in 88 µL of Opti-MEM (Alfagene, Cat.31985062) was added to each well, followed by the addition of 1 µL/well of lipofectamine RNAimax (Invitrogen, Cat.13778075) mix. After an incubation for 30 minutes, 4x10e4 cells/mL were added to each well in complete growth medium without antibiotics. Finally, cells were incubated for 72 hours at 37°C in a CO2 incubator.

value: HeLa

value: cervical cancer cell

value: Cells transfected with a siCtrl


title: E15_FJW161014001_B11

description: EWF-E15_FJW161014001_B11_TGCAGCT-TATCCTC_L006


title: E15_FJW161014001_B09

description: EWF-E15_FJW161014001_B09_CCTAAGA-TATCCTC_L006

value: low


title: E15_FJW161014001_C11

description: EWF-E15_FJW161014001_C11_TGCAGCT-GTAAGGA_L006


title: E15_FJW161014001_B08

description: EWF-E15_FJW161014001_B08_ACTGAGC-TATCCTC_L006


title: E15_FJW161014001_B07

description: EWF-E15_FJW161014001_B07_TAGCGCT-TATCCTC_L006


title: Q175HD/SUMO-KO 2 [431_8]


title: E_cho_3_23

value: EnSC-derived cholangiocyte


title: E_cho_3_22


title: E_cho_3_24


title: Q175HD 3 [431_6]

source_name: Q175HD_Striatal cells

value: Q175 neo-deleted knockin mouse (B6J.129S1-Htttm1.1Mfc/190ChdiJ, stock no. 029928)


title: Q175HD/SUMO-KO 1 [431_7]


title: E15_FJW161014001_B06

description: EWF-E15_FJW161014001_B06_ATGCGCA-TATCCTC_L006


title: E15_FJW161014001_B10

description: EWF-E15_FJW161014001_B10_CGATCAG-TATCCTC_L006


title: E15_FJW161014001_B03

description: EWF-E15_FJW161014001_B03_GCGTAGT-TATCCTC_L006


title: E_cho_3_19


title: E_cho_3_17


title: E_cho_3_20


title: E_cho_3_21


title: E15_FJW161014001_B04

description: EWF-E15_FJW161014001_B04_CGGAGCC-TATCCTC_L006


title: E_cho_3_18


title: E15_FJW161014001_B05

description: EWF-E15_FJW161014001_B05_TACGCTG-TATCCTC_L006


title: E_cho_3_15


title: E15_FJW161014001_B01

description: EWF-E15_FJW161014001_B01_ACTCGCT-TATCCTC_L006


title: E_cho_3_14


title: E15_FJW161014001_A09

description: EWF-E15_FJW161014001_A09_CCTAAGA-CTCTCTA_L006


title: E15_FJW161014001_A10

description: EWF-E15_FJW161014001_A10_CGATCAG-CTCTCTA_L006


title: E_cho_3_13


title: E15_FJW161014001_A11

description: EWF-E15_FJW161014001_A11_TGCAGCT-CTCTCTA_L006


title: E15_FJW161014001_B02

description: EWF-E15_FJW161014001_B02_GGAGCTA-TATCCTC_L006


title: E15_FJW161014001_A08

description: EWF-E15_FJW161014001_A08_ACTGAGC-CTCTCTA_L006


title: E15_FJW161014001_A06

description: EWF-E15_FJW161014001_A06_ATGCGCA-CTCTCTA_L006


title: E15_FJW161014001_A05

description: EWF-E15_FJW161014001_A05_TACGCTG-CTCTCTA_L006


title: E_cho_3_16


title: E_cho_3_12


title: E15_FJW161014001_A03

description: EWF-E15_FJW161014001_A03_GCGTAGT-CTCTCTA_L006


title: E_cho_3_11


title: E15_FJW161014001_A02

description: EWF-E15_FJW161014001_A02_GGAGCTA-CTCTCTA_L006


title: ATAC TET2KO_D3 2

city: Houston

first: Jianfang

last: Li

address: 2121 W. Holcombe Boulevard

institute: Texas A&M University

data_processing:
Remove the low-quality reads of RNA-seq and ATAC-seq by TrimGalore v0.5.0.
Raw scRNA-seq data were demultiplexed, debarcoded, mapped to mm10 reference genome; Clean reads of RNA-seq data were aligned to mm10 using Hisat2 with default parameters; Clean reads of ATAC-seq data were aligned to mm10 using Bowtie2 with ‘--very-sensitive’ option.
The resulting alignment of each sample (with two biological replicates) of ATAC were analyzed by Genrich v.0.5 (https://github.com/jsh58/Genrich) with ATAC-seq mode (option: -j, -q 0.05, -d 150) and the options to remove PCR duplicates and to discard alignments to chrM (-r, -e chrM) to call ATAC peaks.
Count matrix for each gene were generated using htseq-count (HTSeq package); Bedtools merge was used to count the reads fall into non-overlapped ATAC peak regions.
DESeq2 was used to identify significantly differentially expressed genes (DEGs) and Differential Accessible Regions (DARs)
Genome_build: mm10
Supplementary_files_format_and_content: bigwig files for RNA-seq and ATAC-seq samples; text files for scRNA-seq samples.

source_name: CD8+ TILs

growth_protocol: We crossed Tet2-/- mice with OT-1 mice to generate Tet2-/-OT-I mouse model which can recognize chicken ovalbumin (OVA) antigen that expressed on the surface of B16 murine melanoma cells (B16-OVA). In this model, engineered B16-OVA melanoma cells can be recognized and controlled by adoptive transferred OT-I OVA specific CD8+ T cells at early stages of the growth. We collected WT and Tet2KO CD8+ T cells after adoptive transfer at different timepoint for further high-throughput sequencing analysis.

extract_protocol:
RNA was purified using Qiagen RNeasy mini kit. Single-cell RNA-seq libraries were generated using the Chromium Single-Cell 3′ Reagent V2 Kit (10× Genomics). Nuclei were isolated from 50,000 cells in lysis buffer (10 mM Tris-HCl, pH 7.4, 10 mM NaCl, 3 mM MgCl2, 0.1% IGEPAL CA-630).
Single-cell RNA-seq libraries were generated using the Chromium Single-Cell 3′ Reagent V2 Kit (10× Genomics). PolyA tailed mRNA were enriched using NEBNext Poly(A) mRNA Magnetic Isolation Module (NEB). NEBNext Ultra™ II Directional RNA Library Prep Kit for Illumina (NEB) was used to generate RNA-seq libraries. Nuclei were isolated from 50,000 cells in lysis buffer (10 mM Tris-HCl, pH 7.4, 10 mM NaCl, 3 mM MgCl2, 0.1% IGEPAL CA-630), then transposition reaction was performed using Illumina Nextera DNA library preparation kit at 37 °C for 30 min. Tagmented DNA fragments were purified using MinElute PCR purification kit (Qiagen) and purified DNA were amplified with KAPA real-time library amplification kit (Roche). Amplified ATAC-seq libraries were than purified with AmpureXP beads.
scRNA, RNA, ATAC

treatment_protocol: We collected WT and Tet2KO TILs (with and without anti-PD-L1 treatment) 8 days after adoptive T cell transfer for scRNA-seq analysis. We collected WT and Tet2KO TILs before and 3 days after adoptive T cell transfer for RNA-seq and ATAC-seq analysis.

value: TET2 knockout


title: E15_FJW150126001_H12

description: mEWF-E15_FJW150126001_H12_TCGACGT-TTATGCG_L008

value: whisker follicles cells


title: E15_FJW150126001_H10

description: mEWF-E15_FJW150126001_H10_CGATCAG-TTATGCG_L008

value: ok


title: E_cho_3_09


title: E15_FJW161014001_A01

description: EWF-E15_FJW161014001_A01_ACTCGCT-CTCTCTA_L006


title: E_cho_3_10


title: WT 3 [431_3]

source_name: WT_Striatal cells

value: Wild-type


title: WT 1 [431_1]


title: Q175HD 1 [431_4]


title: WT 2 [431_2]


title: E15_FJW150126001_H09

description: mEWF-E15_FJW150126001_H09_CCTAAGA-TTATGCG_L008


title: E15_FJW150126001_H11

description: mEWF-E15_FJW150126001_H11_TGCAGCT-TTATGCG_L008


title: E15_FJW150126001_H07

description: mEWF-E15_FJW150126001_H07_TAGCGCT-TTATGCG_L008


title: E15_FJW150126001_H06

description: mEWF-E15_FJW150126001_H06_ATGCGCA-TTATGCG_L008


title: ATAC TET2KO_D0 1


title: E_cho_3_07


title: E15_FJW150126001_H08

description: mEWF-E15_FJW150126001_H08_ACTGAGC-TTATGCG_L008


title: Q175HD 2 [431_5]


title: ATAC TET2KO_D3 1


title: ATAC TET2KO_D0 2


title: E15_FJW150126001_H05

description: mEWF-E15_FJW150126001_H05_TACGCTG-TTATGCG_L008


title: ATAC WT_D3 2

value: wild-type


title: E_cho_3_06


title: E15_FJW150126001_H04

description: mEWF-E15_FJW150126001_H04_CGGAGCC-TTATGCG_L008


title: E15_FJW150126001_H03

description: mEWF-E15_FJW150126001_H03_GCGTAGT-TTATGCG_L008


title: E_cho_3_08


title: ATAC WT_D3 1


title: E15_FJW150126001_H02

description: mEWF-E15_FJW150126001_H02_GGAGCTA-TTATGCG_L008


title: ATAC WT_D0 2


title: E_cho_3_04


title: E15_FJW150126001_H01

description: mEWF-E15_FJW150126001_H01_ACTCGCT-TTATGCG_L008


title: E15_FJW150126001_G11

description: mEWF-E15_FJW150126001_G11_TGCAGCT-GAGCCTT_L008


title: E15_FJW150126001_G10

description: mEWF-E15_FJW150126001_G10_CGATCAG-GAGCCTT_L008


title: E15_FJW150126001_G12

description: mEWF-E15_FJW150126001_G12_TCGACGT-GAGCCTT_L008


title: E_cho_3_03


title: RNA TET2KO_D3 2


title: E15_FJW150126001_G08

description: mEWF-E15_FJW150126001_G08_ACTGAGC-GAGCCTT_L008


title: E_cho_3_02


title: E15_FJW150126001_G07

description: mEWF-E15_FJW150126001_G07_TAGCGCT-GAGCCTT_L008


title: E15_FJW150126001_G06

description: mEWF-E15_FJW150126001_G06_ATGCGCA-GAGCCTT_L008


title: E_cho_3_05


title: RNA TET2KO_D0 2


title: E_cho_2_08


title: E_cho_2_07


title: E_cho_3_01


title: E15_FJW150126001_G05

description: mEWF-E15_FJW150126001_G05_TACGCTG-GAGCCTT_L008


title: RNA TET2KO_D0 1


title: RNA TET2KO_D3 1


title: E15_FJW150126001_G02

description: mEWF-E15_FJW150126001_G02_GGAGCTA-GAGCCTT_L008


title: E15_FJW150126001_G03

description: mEWF-E15_FJW150126001_G03_GCGTAGT-GAGCCTT_L008


title: E_cho_2_06


title: E15_FJW150126001_F12

description: mEWF-E15_FJW150126001_F12_TCGACGT-AAGGCTA_L008


title: ATAC WT_D0 1


title: RNA WT_D3 2


title: E15_FJW150126001_G09

description: mEWF-E15_FJW150126001_G09_CCTAAGA-GAGCCTT_L008


title: E15_FJW150126001_G01

description: mEWF-E15_FJW150126001_G01_ACTCGCT-GAGCCTT_L008


title: RNA WT_D3 1


title: E_cho_2_05


title: E15_FJW150126001_F09

description: mEWF-E15_FJW150126001_F09_CCTAAGA-AAGGCTA_L008


title: E15_FJW150126001_F11

description: mEWF-E15_FJW150126001_F11_TGCAGCT-AAGGCTA_L008


title: RNA WT_D0 2


title: E15_FJW150126001_F10

description: mEWF-E15_FJW150126001_F10_CGATCAG-AAGGCTA_L008


title: E15_FJW150126001_G04

description: mEWF-E15_FJW150126001_G04_CGGAGCC-GAGCCTT_L008


title: E15_FJW150126001_F08

description: mEWF-E15_FJW150126001_F08_ACTGAGC-AAGGCTA_L008


title: E15_FJW150126001_F07

description: mEWF-E15_FJW150126001_F07_TAGCGCT-AAGGCTA_L008


title: E_cho_2_03


title: RNA WT_D0 1


title: E_cho_2_04


title: E15_FJW150126001_F06

description: mEWF-E15_FJW150126001_F06_ATGCGCA-AAGGCTA_L008


title: scRNA TET2KO_PDL1


title: E_cho_2_02


title: E15_FJW150126001_F01

description: mEWF-E15_FJW150126001_F01_ACTCGCT-AAGGCTA_L008


title: E15_FJW150126001_F04

description: mEWF-E15_FJW150126001_F04_CGGAGCC-AAGGCTA_L008


title: E_cho_2_01


title: E15_FJW150126001_F03

description: mEWF-E15_FJW150126001_F03_GCGTAGT-AAGGCTA_L008


title: scRNA TET2KO_CTL


title: E15_FJW150126001_E12

description: mEWF-E15_FJW150126001_E12_TCGACGT-CTATTAA_L008


title: scRNA WT_PDL1


title: E15_FJW150126001_E11

description: mEWF-E15_FJW150126001_E11_TGCAGCT-CTATTAA_L008


title: E_cho_1_23


title: E15_FJW150126001_E10

description: mEWF-E15_FJW150126001_E10_CGATCAG-CTATTAA_L008


title: E15_FJW150126001_E09

description: mEWF-E15_FJW150126001_E09_CCTAAGA-CTATTAA_L008


title: E_cho_1_22


title: scRNA WT_CTL


title: E15_FJW150126001_E08

description: mEWF-E15_FJW150126001_E08_ACTGAGC-CTATTAA_L008


title: E15_FJW150126001_E07

description: mEWF-E15_FJW150126001_E07_TAGCGCT-CTATTAA_L008


title: E_cho_1_21


title: E15_FJW150126001_E06

description: mEWF-E15_FJW150126001_E06_ATGCGCA-CTATTAA_L008


title: E15_FJW150126001_E04

description: mEWF-E15_FJW150126001_E04_CGGAGCC-CTATTAA_L008


title: E15_FJW150126001_E05

description: mEWF-E15_FJW150126001_E05_TACGCTG-CTATTAA_L008


title: E15_FJW150126001_E02

description: mEWF-E15_FJW150126001_E02_GGAGCTA-CTATTAA_L008


title: E_cho_1_20


title: E13_FJW160126004_DH10

source_name: E13.0_whisker follicles cells


title: E13_FJW160126004_DH11


title: E15_FJW150126001_E01

description: mEWF-E15_FJW150126001_E01_ACTCGCT-CTATTAA_L008


title: E15_FJW150126001_D11

description: mEWF-E15_FJW150126001_D11_TGCAGCT-GCGTAAG_L008


title: E_cho_1_16


title: E13_FJW160126004_DH07


title: E15_FJW150126001_D12

description: mEWF-E15_FJW150126001_D12_TCGACGT-GCGTAAG_L008


title: E15_FJW150126001_D10

description: mEWF-E15_FJW150126001_D10_CGATCAG-GCGTAAG_L008


title: E13_FJW160126004_DH06


title: E13_FJW160126004_DH08


title: E15_FJW150126001_D07

description: mEWF-E15_FJW150126001_D07_TAGCGCT-GCGTAAG_L008


title: E15_FJW150126001_D09

description: mEWF-E15_FJW150126001_D09_CCTAAGA-GCGTAAG_L008


title: E13_FJW160126004_DH05


title: E_cho_1_15


title: E15_FJW150126001_D05

description: mEWF-E15_FJW150126001_D05_TACGCTG-GCGTAAG_L008


title: E15_FJW150126001_D06

description: mEWF-E15_FJW150126001_D06_ATGCGCA-GCGTAAG_L008


title: CSB-KO_UV_6J8h_1

description:
genomic DNA (ChIP)
genome used for mapping:
Hg38

value: CSB-KO

value: 8 hours

value: Pan-RNAPII (Bethyl; A304-405A)


title: E_cho_1_14


title: E13_FJW160126004_DH09


title: E15_FJW150126001_D03

description: mEWF-E15_FJW150126001_D03_GCGTAGT-GCGTAAG_L008


title: E15_FJW150126001_E03

description: mEWF-E15_FJW150126001_E03_GCGTAGT-CTATTAA_L008


title: E_cho_1_19


title: E_cho_1_18


title: E15_FJW150126001_D04

description: mEWF-E15_FJW150126001_D04_CGGAGCC-GCGTAAG_L008


title: E13_FJW160126004_DH04


title: E_cho_1_17


title: E15_FJW150126001_D02

description: mEWF-E15_FJW150126001_D02_GGAGCTA-GCGTAAG_L008


title: E_cho_1_13


title: E15_FJW150126001_D01

description: mEWF-E15_FJW150126001_D01_ACTCGCT-GCGTAAG_L008


title: E_cho_1_12


title: E15_FJW150126001_C12

description: mEWF-E15_FJW150126001_C12_TCGACGT-CCTAGAG_L008


title: E15_FJW150126001_C11

description: mEWF-E15_FJW150126001_C11_TGCAGCT-CCTAGAG_L008


title: E13_FJW160126004_DH03


title: E13_FJW160126004_DH01


title: E_cho_1_11


title: E15_FJW150126001_C10

description: mEWF-E15_FJW150126001_C10_CGATCAG-CCTAGAG_L008


title: E15_FJW150126001_C09

description: mEWF-E15_FJW150126001_C09_CCTAAGA-CCTAGAG_L008


title: E_cho_1_10


title: E15_FJW150126001_C08

description: mEWF-E15_FJW150126001_C08_ACTGAGC-CCTAGAG_L008


title: E13_FJW160126004_DG12


title: E15_FJW150126001_C07

description: mEWF-E15_FJW150126001_C07_TAGCGCT-CCTAGAG_L008


title: E_cho_1_09


title: E15_FJW150126001_C06

description: mEWF-E15_FJW150126001_C06_ATGCGCA-CCTAGAG_L008


title: E13_FJW160126004_DG11


title: E_cho_1_08


title: E15_FJW150126001_C05

description: mEWF-E15_FJW150126001_C05_TACGCTG-CCTAGAG_L008


title: E15_FJW150126001_C04

description: mEWF-E15_FJW150126001_C04_CGGAGCC-CCTAGAG_L008


title: E15_FJW150126001_C02

description: mEWF-E15_FJW150126001_C02_GGAGCTA-CCTAGAG_L008


title: E15_FJW150126001_C03

description: mEWF-E15_FJW150126001_C03_GCGTAGT-CCTAGAG_L008


title: E13_FJW160126004_DG09


title: E_cho_1_06


title: E_cho_1_07


title: E13_FJW160126004_DH02


title: E13_FJW160126004_DG10


title: E13_FJW160126004_DG08


title: E15_FJW150126001_B12

description: mEWF-E15_FJW150126001_B12_TCGACGT-TTCTAGC_L008


title: E_cho_1_05


title: E15_FJW150126001_B09

description: mEWF-E15_FJW150126001_B09_CCTAAGA-TTCTAGC_L008


title: E15_FJW150126001_B10

description: mEWF-E15_FJW150126001_B10_CGATCAG-TTCTAGC_L008


title: E15_FJW150126001_B07

description: mEWF-E15_FJW150126001_B07_TAGCGCT-TTCTAGC_L008


title: E_cho_1_04


title: E15_FJW150126001_B08

description: mEWF-E15_FJW150126001_B08_ACTGAGC-TTCTAGC_L008


title: E13_FJW160126004_DG06


title: E_cho_1_03


title: E15_FJW150126001_B05

description: mEWF-E15_FJW150126001_B05_TACGCTG-TTCTAGC_L008


title: E13_FJW160126004_DG04


title: E_cho_1_02


title: E15_FJW150126001_B04

description: mEWF-E15_FJW150126001_B04_CGGAGCC-TTCTAGC_L008


title: E15_FJW150126001_C01

description: mEWF-E15_FJW150126001_C01_ACTCGCT-CCTAGAG_L008


title: E13_FJW160126004_DG03


title: E_cho_1_01


title: E15_FJW150126001_B06

description: mEWF-E15_FJW150126001_B06_ATGCGCA-TTCTAGC_L008


title: E13_FJW160126004_DG05


title: E15_FJW150126001_A11

description: mEWF-E15_FJW150126001_A11_TGCAGCT-TCGACTA_L008


title: E15_FJW150126001_B03

description: mEWF-E15_FJW150126001_B03_GCGTAGT-TTCTAGC_L008


title: HIB_4_04

source_name: Liver

value: Cultured human primary intrahepatic biliary epithelial cell


title: E13_FJW160126004_DG01


title: E15_FJW150126001_A08

description: mEWF-E15_FJW150126001_A08_ACTGAGC-TCGACTA_L008


title: E15_FJW150126001_A06

description: mEWF-E15_FJW150126001_A06_ATGCGCA-TCGACTA_L008


title: E15_FJW150126001_A07

description: mEWF-E15_FJW150126001_A07_TAGCGCT-TCGACTA_L008


title: E13_FJW160126004_DF12


title: E15_FJW150126001_A05

description: mEWF-E15_FJW150126001_A05_TACGCTG-TCGACTA_L008


title: E13_FJW160126004_DF11


title: HIB_4_02


title: HIB_4_01


title: E15_FJW150126001_B01

description: mEWF-E15_FJW150126001_B01_ACTCGCT-TTCTAGC_L008


title: E15_FJW150126001_A02

description: mEWF-E15_FJW150126001_A02_GGAGCTA-TCGACTA_L008


title: E15_FJW150126001_A04

description: mEWF-E15_FJW150126001_A04_CGGAGCC-TCGACTA_L008


title: E13_FJW160126004_DG02


title: E15_FJW150126001_A09

description: mEWF-E15_FJW150126001_A09_CCTAAGA-TCGACTA_L008


title: HIB_4_05


title: E15_FJW150126001_A03

description: mEWF-E15_FJW150126001_A03_GCGTAGT-TCGACTA_L008


title: HIB_3_10


title: E15_FJW150126001_A01

description: mEWF-E15_FJW150126001_A01_ACTCGCT-TCGACTA_L008


title: E13_FJW160126004_DF09


title: E15_FJW150126001_B02

description: mEWF-E15_FJW150126001_B02_GGAGCTA-TTCTAGC_L008


title: E14_FJW161019003_H12

description: EWF-E14_FJW161019003_H12_TCGACGT-TTATGCG_L005

source_name: E14.0_whisker follicles cells


title: E13_FJW160126004_DG07


title: HIB_4_03


title: HIB_3_09


title: E13_FJW160126004_DF08


title: E14_FJW161019003_H09

description: EWF-E14_FJW161019003_H09_CCTAAGA-TTATGCG_L005


title: HIB_3_07


title: HIB_3_08


title: E13_FJW160126004_DF10


title: E13_FJW160126004_DF07


title: E14_FJW161019003_H10

description: EWF-E14_FJW161019003_H10_CGATCAG-TTATGCG_L005


title: HIB_3_06


title: E14_FJW161019003_H04

description: EWF-E14_FJW161019003_H04_CGGAGCC-TTATGCG_L005


title: HIB_3_05


title: E13_FJW160126004_DF05


title: E14_FJW161019003_H06

description: EWF-E14_FJW161019003_H06_ATGCGCA-TTATGCG_L005


title: E13_FJW160126004_DF04


title: E14_FJW161019003_G12

description: EWF-E14_FJW161019003_G12_TCGACGT-GAGCCTT_L005


title: E14_FJW161019003_H01

description: EWF-E14_FJW161019003_H01_ACTCGCT-TTATGCG_L005


title: HIB_3_04


title: E13_FJW160126004_DF03


title: E14_FJW161019003_G11

description: EWF-E14_FJW161019003_G11_TGCAGCT-GAGCCTT_L005


title: E14_FJW161019003_H02

description: EWF-E14_FJW161019003_H02_GGAGCTA-TTATGCG_L005


title: E14_FJW161019003_G10

description: EWF-E14_FJW161019003_G10_CGATCAG-GAGCCTT_L005


title: E14_FJW161019003_H11

description: EWF-E14_FJW161019003_H11_TGCAGCT-TTATGCG_L005


title: E14_FJW161019003_G09

description: EWF-E14_FJW161019003_G09_CCTAAGA-GAGCCTT_L005


title: E13_FJW160126004_DF02


title: E14_FJW161019003_H08

description: EWF-E14_FJW161019003_H08_ACTGAGC-TTATGCG_L005


title: HIB_3_02


title: E14_FJW161019003_H05

description: EWF-E14_FJW161019003_H05_TACGCTG-TTATGCG_L005


title: E14_FJW161019003_G08

description: EWF-E14_FJW161019003_G08_ACTGAGC-GAGCCTT_L005


title: E13_FJW160126004_DF06


title: E14_FJW161019003_G07

description: EWF-E14_FJW161019003_G07_TAGCGCT-GAGCCTT_L005


title: E14_FJW161019003_H03

description: EWF-E14_FJW161019003_H03_GCGTAGT-TTATGCG_L005


title: HIB_3_01


title: E13_FJW160126004_DE12


title: E13_FJW160126004_DF01


title: E14_FJW161019003_G05

description: EWF-E14_FJW161019003_G05_TACGCTG-GAGCCTT_L005


title: HIB_2_09


title: E13_FJW160126004_DE10


title: HIB_3_03


title: E14_FJW161019003_G03

description: EWF-E14_FJW161019003_G03_GCGTAGT-GAGCCTT_L005


title: HIB_2_08


title: E14_FJW161019003_F12

description: EWF-E14_FJW161019003_F12_TCGACGT-AAGGCTA_L005


title: E14_FJW161019003_G02

description: EWF-E14_FJW161019003_G02_GGAGCTA-GAGCCTT_L005


title: HIB_2_07


title: E14_FJW161019003_G01

description: EWF-E14_FJW161019003_G01_ACTCGCT-GAGCCTT_L005


title: HIB_2_06


title: E13_FJW160126004_DE09


title: E14_FJW161019003_F11

description: EWF-E14_FJW161019003_F11_TGCAGCT-AAGGCTA_L005


title: E13_FJW160126004_DE08


title: E14_FJW161019003_F10

description: EWF-E14_FJW161019003_F10_CGATCAG-AAGGCTA_L005


title: E13_FJW160126004_DE07


title: E14_FJW161019003_F09

description: EWF-E14_FJW161019003_F09_CCTAAGA-AAGGCTA_L005


title: E13_FJW160126004_DE06


title: E14_FJW161019003_G06

description: EWF-E14_FJW161019003_G06_ATGCGCA-GAGCCTT_L005


title: E14_FJW161019003_F08

description: EWF-E14_FJW161019003_F08_ACTGAGC-AAGGCTA_L005


title: E14_FJW161019003_F07

description: EWF-E14_FJW161019003_F07_TAGCGCT-AAGGCTA_L005


title: HIB_2_05


title: E14_FJW161019003_F06

description: EWF-E14_FJW161019003_F06_ATGCGCA-AAGGCTA_L005


title: E14_FJW161019003_G04

description: EWF-E14_FJW161019003_G04_CGGAGCC-GAGCCTT_L005


title: E14_FJW161019003_F05

description: EWF-E14_FJW161019003_F05_TACGCTG-AAGGCTA_L005


title: E13_FJW160126004_DE05


title: E14_FJW161019003_F04

description: EWF-E14_FJW161019003_F04_CGGAGCC-AAGGCTA_L005


title: E13_FJW160126004_DE04


title: E14_FJW161019003_F03

description: EWF-E14_FJW161019003_F03_GCGTAGT-AAGGCTA_L005


title: HIB_2_03


title: E14_FJW161019003_F02

description: EWF-E14_FJW161019003_F02_GGAGCTA-AAGGCTA_L005


title: E13_FJW160126004_DE03


title: E14_FJW161019003_F01

description: EWF-E14_FJW161019003_F01_ACTCGCT-AAGGCTA_L005


title: E13_FJW160126004_DE02


title: E14_FJW161019003_E12

description: EWF-E14_FJW161019003_E12_TCGACGT-CTATTAA_L005


title: E14_FJW161019003_E11

description: EWF-E14_FJW161019003_E11_TGCAGCT-CTATTAA_L005


title: HIB_2_01


title: HIB_2_02


title: E13_FJW160126004_DE01


title: E14_FJW161019003_E10

description: EWF-E14_FJW161019003_E10_CGATCAG-CTATTAA_L005


title: E14_FJW161019003_E09

description: EWF-E14_FJW161019003_E09_CCTAAGA-CTATTAA_L005


title: HIB_1_09


title: E14_FJW161019003_E08

description: EWF-E14_FJW161019003_E08_ACTGAGC-CTATTAA_L005


title: HIB_2_04


title: E14_FJW161019003_E06

description: EWF-E14_FJW161019003_E06_ATGCGCA-CTATTAA_L005


title: E13_FJW160126004_DD11


title: E13_FJW160126004_DD12


title: E14_FJW161019003_E07

description: EWF-E14_FJW161019003_E07_TAGCGCT-CTATTAA_L005


title: HIB_1_08


title: HIB_1_07


title: E14_FJW161019003_E04

description: EWF-E14_FJW161019003_E04_CGGAGCC-CTATTAA_L005


title: E13_FJW160126004_DD10


title: E14_FJW161019003_E05

description: EWF-E14_FJW161019003_E05_TACGCTG-CTATTAA_L005


title: E14_FJW161019003_E02

description: EWF-E14_FJW161019003_E02_GGAGCTA-CTATTAA_L005


title: HIB_1_06


title: HIB_1_10


title: E13_FJW160126004_DD09


title: HIB_1_05


title: E14_FJW161019003_D11

description: EWF-E14_FJW161019003_D11_TGCAGCT-GCGTAAG_L005


title: E14_FJW161019003_D12

description: EWF-E14_FJW161019003_D12_TCGACGT-GCGTAAG_L005


title: E13_FJW160126004_DD08


title: HIB_1_04


title: E14_FJW161019003_E01

description: EWF-E14_FJW161019003_E01_ACTCGCT-CTATTAA_L005


title: E14_FJW161019003_D09

description: EWF-E14_FJW161019003_D09_CCTAAGA-GCGTAAG_L005


title: E13_FJW160126004_DD07


title: E13_FJW160126004_DD06


title: E14_FJW161019003_D10

description: EWF-E14_FJW161019003_D10_CGATCAG-GCGTAAG_L005


title: E14_FJW161019003_D08

description: EWF-E14_FJW161019003_D08_ACTGAGC-GCGTAAG_L005


title: HIB_1_03


title: E14_FJW161019003_D07

description: EWF-E14_FJW161019003_D07_TAGCGCT-GCGTAAG_L005


title: E14_FJW161019003_E03

description: EWF-E14_FJW161019003_E03_GCGTAGT-CTATTAA_L005


title: HIB_1_02


title: E14_FJW161019003_D06

description: EWF-E14_FJW161019003_D06_ATGCGCA-GCGTAAG_L005


title: HIB_1_01


title: E14_FJW161019003_D05

description: EWF-E14_FJW161019003_D05_TACGCTG-GCGTAAG_L005


title: E13_FJW160126004_DD05


title: E14_FJW161019003_D04

description: EWF-E14_FJW161019003_D04_CGGAGCC-GCGTAAG_L005


title: E13_FJW160126004_DD04


title: E14_FJW161019003_D02

description: EWF-E14_FJW161019003_D02_GGAGCTA-GCGTAAG_L005


title: Hepatoblast_4_08

value: EnSC-derived hepatoblast


title: E13_FJW160126004_DD03


title: E14_FJW161019003_D01

description: EWF-E14_FJW161019003_D01_ACTCGCT-GCGTAAG_L005


title: E14_FJW161019003_D03

description: EWF-E14_FJW161019003_D03_GCGTAGT-GCGTAAG_L005


title: Hepatoblast_4_07


title: Hepatoblast_4_06


title: E14_FJW161019003_C12

description: EWF-E14_FJW161019003_C12_TCGACGT-CCTAGAG_L005


title: E13_FJW160126004_DD02


title: E14_FJW161019003_C10

description: EWF-E14_FJW161019003_C10_CGATCAG-CCTAGAG_L005


title: E13_FJW160126004_DD01


title: E14_FJW161019003_C11

description: EWF-E14_FJW161019003_C11_TGCAGCT-CCTAGAG_L005


title: E15_FJW150126001_A10

description: mEWF-E15_FJW150126001_A10_CGATCAG-TCGACTA_L008


title: Hepatoblast_4_04


title: Hepatoblast_4_05


title: E14_FJW161019003_C08

description: EWF-E14_FJW161019003_C08_ACTGAGC-CCTAGAG_L005


title: E13_FJW160126004_DC11


title: E14_FJW161019003_C06

description: EWF-E14_FJW161019003_C06_ATGCGCA-CCTAGAG_L005


title: E13_FJW160126004_DC10


title: E13_FJW160126004_DC09


title: E14_FJW161019003_C03

description: EWF-E14_FJW161019003_C03_GCGTAGT-CCTAGAG_L005


title: E14_FJW161019003_C04

description: EWF-E14_FJW161019003_C04_CGGAGCC-CCTAGAG_L005


title: E13_FJW160126004_DC12


title: E14_FJW161019003_C01

description: EWF-E14_FJW161019003_C01_ACTCGCT-CCTAGAG_L005


title: E14_FJW161019003_C05

description: EWF-E14_FJW161019003_C05_TACGCTG-CCTAGAG_L005


title: E13_FJW160126004_DC08


title: Hepatoblast_4_01


title: E14_FJW161019003_C09

description: EWF-E14_FJW161019003_C09_CCTAAGA-CCTAGAG_L005


title: E14_FJW161019003_B11

description: EWF-E14_FJW161019003_B11_TGCAGCT-TTCTAGC_L005


title: Hepatoblast_3_22


title: E14_FJW161019003_B08

description: EWF-E14_FJW161019003_B08_ACTGAGC-TTCTAGC_L005


title: E14_FJW161019003_B09

description: EWF-E14_FJW161019003_B09_CCTAAGA-TTCTAGC_L005


title: E14_FJW161019003_C07

description: EWF-E14_FJW161019003_C07_TAGCGCT-CCTAGAG_L005


title: Hepatoblast_4_02


title: E14_FJW161019003_B07

description: EWF-E14_FJW161019003_B07_TAGCGCT-TTCTAGC_L005


title: Hepatoblast_3_21


title: E14_FJW161019003_C02

description: EWF-E14_FJW161019003_C02_GGAGCTA-CCTAGAG_L005


title: E13_FJW160126004_DC06


title: E13_FJW160126004_DC07


title: E14_FJW161019003_B06

description: EWF-E14_FJW161019003_B06_ATGCGCA-TTCTAGC_L005


title: E14_FJW161019003_B05

description: EWF-E14_FJW161019003_B05_TACGCTG-TTCTAGC_L005


title: E15_FJW150126001_B11

description: mEWF-E15_FJW150126001_B11_TGCAGCT-TTCTAGC_L008


title: E14_FJW161019003_B04

description: EWF-E14_FJW161019003_B04_CGGAGCC-TTCTAGC_L005


title: E13_FJW160126004_DC05


title: Hepatoblast_4_03


title: E14_FJW161019003_B12

description: EWF-E14_FJW161019003_B12_TCGACGT-TTCTAGC_L005


title: Hepatoblast_3_19


title: E14_FJW161019003_B03

description: EWF-E14_FJW161019003_B03_GCGTAGT-TTCTAGC_L005


title: E14_FJW161019003_B01

description: EWF-E14_FJW161019003_B01_ACTCGCT-TTCTAGC_L005


title: E14_FJW161019003_A11

description: EWF-E14_FJW161019003_A11_TGCAGCT-TCGACTA_L005


title: Hepatoblast_3_18


title: E13_FJW160126004_DC04


title: E13_FJW160126004_DC03


title: E14_FJW161019003_A10

description: EWF-E14_FJW161019003_A10_CGATCAG-TCGACTA_L005


title: E14_FJW161019003_A09

description: EWF-E14_FJW161019003_A09_CCTAAGA-TCGACTA_L005


title: E13_FJW160126004_DC02


title: Hepatoblast_3_17


title: E14_FJW161019003_A08

description: EWF-E14_FJW161019003_A08_ACTGAGC-TCGACTA_L005


title: E14_FJW161019003_A05

description: EWF-E14_FJW161019003_A05_TACGCTG-TCGACTA_L005


title: Hepatoblast_3_16


title: E14_FJW161019003_A04

description: EWF-E14_FJW161019003_A04_CGGAGCC-TCGACTA_L005


title: E14_FJW161019003_A06

description: EWF-E14_FJW161019003_A06_ATGCGCA-TCGACTA_L005


title: E14_FJW161019003_A03

description: EWF-E14_FJW161019003_A03_GCGTAGT-TCGACTA_L005


title: E13_FJW160126004_DB12


title: Hepatoblast_3_20


title: E13_FJW160126004_DC01


title: E13_FJW160126004_DB11


title: Hepatoblast_3_14


title: E14_FJW161019003_A01

description: EWF-E14_FJW161019003_A01_ACTCGCT-TCGACTA_L005


title: E14_FJW161019002_H12

description: EWF-E14_FJW161019002_H12_ATCTCAG-TCTCTCC_L004


title: Hepatoblast_3_13


title: E14_FJW161019002_H11

description: EWF-E14_FJW161019002_H11_GCTCATG-TCTCTCC_L004


title: E13_FJW160126004_DB10


title: Hepatoblast_3_12


title: E14_FJW161019002_H10

description: EWF-E14_FJW161019002_H10_GTAGAGG-TCTCTCC_L004


title: E13_FJW160126004_DB09


title: E13_FJW160126004_DB08


title: E14_FJW161019002_H09

description: EWF-E14_FJW161019002_H09_AAGAGGC-TCTCTCC_L004


title: Hepatoblast_3_11


title: E14_FJW161019002_H07

description: EWF-E14_FJW161019002_H07_CTCTCTA-TCTCTCC_L004


title: Hepatoblast_3_10


title: E14_FJW161019002_H08

description: EWF-E14_FJW161019002_H08_CGAGGCT-TCTCTCC_L004


title: E14_FJW161019002_H06

description: EWF-E14_FJW161019002_H06_TAGGCAT-TCTCTCC_L004


title: Hepatoblast_3_09


title: E13_FJW160126004_DB07


title: E14_FJW161019002_H04

description: EWF-E14_FJW161019002_H04_TCCTGAG-TCTCTCC_L004


title: Hepatoblast_3_15


title: E14_FJW161019002_H05

description: EWF-E14_FJW161019002_H05_GGACTCC-TCTCTCC_L004


title: E13_FJW160126004_DB06


title: E14_FJW161019003_A02

description: EWF-E14_FJW161019003_A02_GGAGCTA-TCGACTA_L005


title: E14_FJW161019002_H03

description: EWF-E14_FJW161019002_H03_AGGCAGA-TCTCTCC_L004


title: Hepatoblast_3_08


title: E13_FJW160126004_DB05


title: E14_FJW161019002_H01

description: EWF-E14_FJW161019002_H01_TAAGGCG-TCTCTCC_L004


title: Hepatoblast_3_07


title: E14_FJW161019002_G11

description: EWF-E14_FJW161019002_G11_GCTCATG-CGTCTAA_L004


title: E14_FJW161019002_G10

description: EWF-E14_FJW161019002_G10_GTAGAGG-CGTCTAA_L004


title: Hepatoblast_3_06


title: E14_FJW161019002_G08

description: EWF-E14_FJW161019002_G08_CGAGGCT-CGTCTAA_L004


title: E14_FJW161019002_G09

description: EWF-E14_FJW161019002_G09_AAGAGGC-CGTCTAA_L004


title: Hepatoblast_3_05


title: E14_FJW161019002_G07

description: EWF-E14_FJW161019002_G07_CTCTCTA-CGTCTAA_L004


title: E13_FJW160126004_DB02


title: E14_FJW161019002_G06

description: EWF-E14_FJW161019002_G06_TAGGCAT-CGTCTAA_L004


title: E14_FJW161019002_G05

description: EWF-E14_FJW161019002_G05_GGACTCC-CGTCTAA_L004


title: E14_FJW161019002_G04

description: EWF-E14_FJW161019002_G04_TCCTGAG-CGTCTAA_L004


title: E14_FJW161019002_G03

description: EWF-E14_FJW161019002_G03_AGGCAGA-CGTCTAA_L004


title: Hepatoblast_3_03


title: E13_FJW160126004_DA11


title: E14_FJW161019002_G02

description: EWF-E14_FJW161019002_G02_CGTACTA-CGTCTAA_L004


title: E13_FJW160126004_DB01


title: E14_FJW161019002_G01

description: EWF-E14_FJW161019002_G01_TAAGGCG-CGTCTAA_L004


title: Hepatoblast_3_02


title: Hepatoblast_3_01


title: E14_FJW161019002_F12

description: EWF-E14_FJW161019002_F12_ATCTCAG-CTAAGCC_L004


title: E13_FJW160126004_DA08


title: E13_FJW160126004_DB04


title: E14_FJW161019002_F09

description: EWF-E14_FJW161019002_F09_AAGAGGC-CTAAGCC_L004


title: E14_FJW161019002_F08

description: EWF-E14_FJW161019002_F08_CGAGGCT-CTAAGCC_L004


title: E13_FJW160126004_DA05


title: Hepatoblast_2_23


title: E14_FJW161019002_F05

description: EWF-E14_FJW161019002_F05_GGACTCC-CTAAGCC_L004


title: E13_FJW160126004_DA04


title: E14_FJW161019002_F06

description: EWF-E14_FJW161019002_F06_TAGGCAT-CTAAGCC_L004


title: Hepatoblast_3_04


title: E14_FJW161019002_F04

description: EWF-E14_FJW161019002_F04_TCCTGAG-CTAAGCC_L004


title: Hepatoblast_2_21


title: E13_FJW160126004_DA03


title: E14_FJW161019002_F03

description: EWF-E14_FJW161019002_F03_AGGCAGA-CTAAGCC_L004


title: E14_FJW161019002_F02

description: EWF-E14_FJW161019002_F02_CGTACTA-CTAAGCC_L004


title: E13_FJW160126004_DA10


title: E13_FJW160126004_DA02


title: Hepatoblast_2_22


title: Hepatoblast_2_19


title: E14_FJW161019002_E12

description: EWF-E14_FJW161019002_E12_ATCTCAG-AAGGAGT_L004


title: Hepatoblast_2_20


title: E14_FJW161019002_F07

description: EWF-E14_FJW161019002_F07_CTCTCTA-CTAAGCC_L004


title: E13_FJW160126002_AH12


title: E14_FJW161019002_E11

description: EWF-E14_FJW161019002_E11_GCTCATG-AAGGAGT_L004


title: E13_FJW160126002_AH11


title: E14_FJW161019002_E10

description: EWF-E14_FJW161019002_E10_GTAGAGG-AAGGAGT_L004


title: E14_FJW161019002_F10

description: EWF-E14_FJW161019002_F10_GTAGAGG-CTAAGCC_L004


title: Hepatoblast_2_18


title: E13_FJW160126004_DA01


title: E14_FJW161019002_E07

description: EWF-E14_FJW161019002_E07_CTCTCTA-AAGGAGT_L004


title: E14_FJW161019002_E09

description: EWF-E14_FJW161019002_E09_AAGAGGC-AAGGAGT_L004


title: E14_FJW161019002_E08

description: EWF-E14_FJW161019002_E08_CGAGGCT-AAGGAGT_L004


title: E13_FJW160126002_AH10


title: Hepatoblast_2_16


title: E14_FJW161019002_E06

description: EWF-E14_FJW161019002_E06_TAGGCAT-AAGGAGT_L004


title: E14_FJW161019002_E05

description: EWF-E14_FJW161019002_E05_GGACTCC-AAGGAGT_L004


title: Hepatoblast_2_15


title: E14_FJW161019002_E04

description: EWF-E14_FJW161019002_E04_TCCTGAG-AAGGAGT_L004


title: E14_FJW161019002_E03

description: EWF-E14_FJW161019002_E03_AGGCAGA-AAGGAGT_L004


title: E14_FJW161019002_F01

description: EWF-E14_FJW161019002_F01_TAAGGCG-CTAAGCC_L004


title: E13_FJW160126002_AH09


title: E14_FJW161019002_E02

description: EWF-E14_FJW161019002_E02_CGTACTA-AAGGAGT_L004


title: Hepatoblast_2_14


title: E13_FJW160126002_AH07


title: E14_FJW161019002_E01

description: EWF-E14_FJW161019002_E01_TAAGGCG-AAGGAGT_L004


title: E13_FJW160126002_AH06


title: E14_FJW161019002_D12

description: EWF-E14_FJW161019002_D12_ATCTCAG-ACTGCAT_L004


title: E14_FJW161019002_D11

description: EWF-E14_FJW161019002_D11_GCTCATG-ACTGCAT_L004


title: E14_FJW161019002_D10

description: EWF-E14_FJW161019002_D10_GTAGAGG-ACTGCAT_L004


title: Hepatoblast_2_13


title: E14_FJW161019002_D08

description: EWF-E14_FJW161019002_D08_CGAGGCT-ACTGCAT_L004


title: E14_FJW161019002_D09

description: EWF-E14_FJW161019002_D09_AAGAGGC-ACTGCAT_L004


title: Hepatoblast_2_11


title: E14_FJW161019002_D07

description: EWF-E14_FJW161019002_D07_CTCTCTA-ACTGCAT_L004


title: E13_FJW160126002_AH04


title: Hepatoblast_2_10


title: E13_FJW160126002_AH03


title: E13_FJW160126002_AH05


title: E14_FJW161019002_D05

description: EWF-E14_FJW161019002_D05_GGACTCC-ACTGCAT_L004


title: Hepatoblast_2_09


title: E14_FJW161019002_D04

description: EWF-E14_FJW161019002_D04_TCCTGAG-ACTGCAT_L004


title: E13_FJW160126002_AH02


title: Hepatoblast_2_17


title: E13_FJW160126002_AH01


title: E14_FJW161019002_D02

description: EWF-E14_FJW161019002_D02_CGTACTA-ACTGCAT_L004


title: E14_FJW161019002_D01

description: EWF-E14_FJW161019002_D01_TAAGGCG-ACTGCAT_L004


title: Hepatoblast_2_12


title: E14_FJW161019002_C12

description: EWF-E14_FJW161019002_C12_ATCTCAG-GTAAGGA_L004


title: Hepatoblast_2_06


title: E14_FJW161019002_C11

description: EWF-E14_FJW161019002_C11_GCTCATG-GTAAGGA_L004


title: E13_FJW160126002_AG12


title: E14_FJW161019002_C10

description: EWF-E14_FJW161019002_C10_GTAGAGG-GTAAGGA_L004


title: E14_FJW161019002_C09

description: EWF-E14_FJW161019002_C09_AAGAGGC-GTAAGGA_L004


title: E14_FJW161019002_D06

description: EWF-E14_FJW161019002_D06_TAGGCAT-ACTGCAT_L004


title: E13_FJW160126002_AG10


title: Hepatoblast_2_05


title: E14_FJW161019002_C06

description: EWF-E14_FJW161019002_C06_TAGGCAT-GTAAGGA_L004


title: E13_FJW160126002_AG11


title: E14_FJW161019002_C07

description: EWF-E14_FJW161019002_C07_CTCTCTA-GTAAGGA_L004


title: E14_FJW161019002_C05

description: EWF-E14_FJW161019002_C05_GGACTCC-GTAAGGA_L004


title: E13_FJW160126002_AG09


title: Hepatoblast_2_04


title: Hepatoblast_2_03


title: E14_FJW161019002_D03

description: EWF-E14_FJW161019002_D03_AGGCAGA-ACTGCAT_L004


title: E14_FJW161019002_C04

description: EWF-E14_FJW161019002_C04_TCCTGAG-GTAAGGA_L004


title: E14_FJW161019002_C03

description: EWF-E14_FJW161019002_C03_AGGCAGA-GTAAGGA_L004


title: E14_FJW161019002_C02

description: EWF-E14_FJW161019002_C02_CGTACTA-GTAAGGA_L004


title: Hepatoblast_2_08


title: E13_FJW160126002_AG08


title: Hepatoblast_2_02


title: E13_FJW160126002_AG07


title: E14_FJW161019002_B12

description: EWF-E14_FJW161019002_B12_ATCTCAG-TATCCTC_L004


title: E14_FJW161019002_C01

description: EWF-E14_FJW161019002_C01_TAAGGCG-GTAAGGA_L004


title: Hepatoblast_2_07


title: Hepatoblast_2_01


title: E14_FJW161019002_B10

description: EWF-E14_FJW161019002_B10_GTAGAGG-TATCCTC_L004


title: E14_FJW161019002_B09

description: EWF-E14_FJW161019002_B09_AAGAGGC-TATCCTC_L004


title: E14_FJW161019002_B08

description: EWF-E14_FJW161019002_B08_CGAGGCT-TATCCTC_L004


title: E13_FJW160126002_AG04


title: Hepatoblast_1_30


title: E14_FJW161019002_B07

description: EWF-E14_FJW161019002_B07_CTCTCTA-TATCCTC_L004


title: E13_FJW160126002_AG05


title: E14_FJW161019002_B06

description: EWF-E14_FJW161019002_B06_TAGGCAT-TATCCTC_L004


title: Hepatoblast_1_29


title: E14_FJW161019002_B04

description: EWF-E14_FJW161019002_B04_TCCTGAG-TATCCTC_L004


title: Hepatoblast_1_28


title: E14_FJW161019002_B03

description: EWF-E14_FJW161019002_B03_AGGCAGA-TATCCTC_L004


title: E14_FJW161019002_B05

description: EWF-E14_FJW161019002_B05_GGACTCC-TATCCTC_L004


title: E13_FJW160126002_AG02


title: E14_FJW161019002_B02

description: EWF-E14_FJW161019002_B02_CGTACTA-TATCCTC_L004


title: E13_FJW160126002_AG01


title: E14_FJW161019002_B01

description: EWF-E14_FJW161019002_B01_TAAGGCG-TATCCTC_L004


title: E14_FJW161019002_A11

description: EWF-E14_FJW161019002_A11_GCTCATG-CTCTCTA_L004


title: E14_FJW161019002_A10

description: EWF-E14_FJW161019002_A10_GTAGAGG-CTCTCTA_L004


title: Hepatoblast_1_26


title: Hepatoblast_1_31


title: E14_FJW161019002_B11

description: EWF-E14_FJW161019002_B11_GCTCATG-TATCCTC_L004


title: E13_FJW160126002_AG06


title: E14_FJW161019002_A08

description: EWF-E14_FJW161019002_A08_CGAGGCT-CTCTCTA_L004


title: E14_FJW161019002_A09

description: EWF-E14_FJW161019002_A09_AAGAGGC-CTCTCTA_L004


title: E13_FJW160126002_AF11


title: E13_FJW160126002_AG03


title: Hepatoblast_1_25


title: E14_FJW161019002_A06

description: EWF-E14_FJW161019002_A06_TAGGCAT-CTCTCTA_L004


title: E13_FJW160126002_AF10


title: E14_FJW161019002_A05

description: EWF-E14_FJW161019002_A05_GGACTCC-CTCTCTA_L004


title: Hepatoblast_1_24


title: Hepatoblast_1_23


title: E14_FJW161019002_A07

description: EWF-E14_FJW161019002_A07_CTCTCTA-CTCTCTA_L004


title: E14_FJW161019002_A04

description: EWF-E14_FJW161019002_A04_TCCTGAG-CTCTCTA_L004


title: Hepatoblast_1_27


title: E13_FJW160126002_AF09


title: Hepatoblast_1_22


title: E13_FJW160126002_AF12


title: E14_FJW161019002_A01

description: EWF-E14_FJW161019002_A01_TAAGGCG-CTCTCTA_L004


title: E13_FJW160126002_AF07


title: E13_FJW161012003_H10

description: EWF-E13_FJW161012003_H10_GTAGAGG-TCTCTCC_L003

source_name: E13.5_whisker follicles cells


title: E13_FJW161012003_H11

description: EWF-E13_FJW161012003_H11_GCTCATG-TCTCTCC_L003


title: Hepatoblast_1_20


title: E14_FJW161019002_A03

description: EWF-E14_FJW161019002_A03_AGGCAGA-CTCTCTA_L004


title: E13_FJW161012003_H12

description: EWF-E13_FJW161012003_H12_ATCTCAG-TCTCTCC_L003


title: E14_FJW161019002_A02

description: EWF-E14_FJW161019002_A02_CGTACTA-CTCTCTA_L004


title: E13_FJW160126002_AF06


title: Hepatoblast_1_21


title: E13_FJW161012003_H09

description: EWF-E13_FJW161012003_H09_AAGAGGC-TCTCTCC_L003


title: E14_FJW161019002_H02

description: EWF-E14_FJW161019002_H02_CGTACTA-TCTCTCC_L004


title: E13_FJW161012003_H08

description: EWF-E13_FJW161012003_H08_CGAGGCT-TCTCTCC_L003


title: E13_FJW160126002_AF05


title: Hepatoblast_1_19


title: E13_FJW161012003_H07

description: EWF-E13_FJW161012003_H07_CTCTCTA-TCTCTCC_L003


title: E13_FJW160126002_AF04


title: Hepatoblast_1_18


title: E13_FJW161012003_H06

description: EWF-E13_FJW161012003_H06_TAGGCAT-TCTCTCC_L003


title: Hepatoblast_1_17


title: E13_FJW160126002_AF08


title: E13_FJW161012003_H05

description: EWF-E13_FJW161012003_H05_GGACTCC-TCTCTCC_L003


title: E13_FJW161012003_H04

description: EWF-E13_FJW161012003_H04_TCCTGAG-TCTCTCC_L003


title: E13_FJW160126004_DB03


title: E13_FJW160126002_AF03


title: E13_FJW161012003_H02

description: EWF-E13_FJW161012003_H02_CGTACTA-TCTCTCC_L003


title: E13_FJW161012003_H01

description: EWF-E13_FJW161012003_H01_TAAGGCG-TCTCTCC_L003


title: E13_FJW160126002_AF02


title: Hepatoblast_1_15


title: Hepatoblast_1_16


title: E13_FJW161012003_G12

description: EWF-E13_FJW161012003_G12_ATCTCAG-CGTCTAA_L003


title: E13_FJW160126002_AF01


title: Hepatoblast_1_14


title: E13_FJW161012003_G09

description: EWF-E13_FJW161012003_G09_AAGAGGC-CGTCTAA_L003


title: E13_FJW161012003_G10

description: EWF-E13_FJW161012003_G10_GTAGAGG-CGTCTAA_L003


title: E13_FJW161012003_G11

description: EWF-E13_FJW161012003_G11_GCTCATG-CGTCTAA_L003


title: E13_FJW161012003_G08

description: EWF-E13_FJW161012003_G08_CGAGGCT-CGTCTAA_L003


title: Hepatoblast_1_13


title: E13_FJW160126002_AE11


title: E13_FJW160126002_AE12


title: E13_FJW161012003_G07

description: EWF-E13_FJW161012003_G07_CTCTCTA-CGTCTAA_L003


title: Hepatoblast_1_12


title: E13_FJW161012003_G06

description: EWF-E13_FJW161012003_G06_TAGGCAT-CGTCTAA_L003


title: E13_FJW161012003_H03

description: EWF-E13_FJW161012003_H03_AGGCAGA-TCTCTCC_L003


title: E13_FJW160126002_AE09


title: Hepatoblast_1_11


title: E13_FJW161012003_G04

description: EWF-E13_FJW161012003_G04_TCCTGAG-CGTCTAA_L003


title: Hepatoblast_1_10


title: E13_FJW160126002_AE08


title: E13_FJW161012003_G02

description: EWF-E13_FJW161012003_G02_CGTACTA-CGTCTAA_L003


title: E13_FJW161012003_G03

description: EWF-E13_FJW161012003_G03_AGGCAGA-CGTCTAA_L003


title: E13_FJW161012003_G05

description: EWF-E13_FJW161012003_G05_GGACTCC-CGTCTAA_L003


title: E13_FJW161012003_G01

description: EWF-E13_FJW161012003_G01_TAAGGCG-CGTCTAA_L003


title: E13_FJW161012003_F12

description: EWF-E13_FJW161012003_F12_ATCTCAG-CTAAGCC_L003


title: E13_FJW160126002_AE07


title: Hepatoblast_1_09


title: E13_FJW161012003_F11

description: EWF-E13_FJW161012003_F11_GCTCATG-CTAAGCC_L003


title: Hepatoblast_1_08


title: E13_FJW161012003_F10

description: EWF-E13_FJW161012003_F10_GTAGAGG-CTAAGCC_L003


title: E13_FJW160126002_AE06


title: E13_FJW161012003_F09

description: EWF-E13_FJW161012003_F09_AAGAGGC-CTAAGCC_L003


title: E13_FJW161012003_F07

description: EWF-E13_FJW161012003_F07_CTCTCTA-CTAAGCC_L003


title: E13_FJW161012003_F06

description: EWF-E13_FJW161012003_F06_TAGGCAT-CTAAGCC_L003


title: E13_FJW161012003_F08

description: EWF-E13_FJW161012003_F08_CGAGGCT-CTAAGCC_L003


title: E13_FJW161012003_F05

description: EWF-E13_FJW161012003_F05_GGACTCC-CTAAGCC_L003


title: Hepatoblast_1_07


title: E13_FJW160126002_AE10


title: E13_FJW160126002_AE04


title: E13_FJW161012003_F04

description: EWF-E13_FJW161012003_F04_TCCTGAG-CTAAGCC_L003


title: E13_FJW161012003_F03

description: EWF-E13_FJW161012003_F03_AGGCAGA-CTAAGCC_L003


title: Hepatoblast_1_04


title: E13_FJW160126002_AE03


title: E13_FJW161012003_F02

description: EWF-E13_FJW161012003_F02_CGTACTA-CTAAGCC_L003


title: E13_FJW161012003_F01

description: EWF-E13_FJW161012003_F01_TAAGGCG-CTAAGCC_L003


title: E13_FJW160126002_AE02


title: E13_FJW160126002_AE05


title: E13_FJW161012003_E11

description: EWF-E13_FJW161012003_E11_GCTCATG-AAGGAGT_L003


title: E13_FJW160126002_AE01


title: Hepatoblast_1_02


title: E13_FJW161012003_E10

description: EWF-E13_FJW161012003_E10_GTAGAGG-AAGGAGT_L003


title: E13_FJW160126002_AD12


title: E13_FJW161012003_E09

description: EWF-E13_FJW161012003_E09_AAGAGGC-AAGGAGT_L003


title: Hepatoblast_1_01


title: E13_FJW160126002_AD11


title: E13_FJW161012003_E07

description: EWF-E13_FJW161012003_E07_CTCTCTA-AAGGAGT_L003


title: Hepatic_Endoderm_3_08

value: EnSC-derived hepatic endoderm


title: Hepatic_Endoderm_3_07


title: E13_FJW161012003_E06

description: EWF-E13_FJW161012003_E06_TAGGCAT-AAGGAGT_L003


title: E13_FJW160126002_AD10


title: E13_FJW161012003_E05

description: EWF-E13_FJW161012003_E05_GGACTCC-AAGGAGT_L003


title: E13_FJW161012003_E12

description: EWF-E13_FJW161012003_E12_ATCTCAG-AAGGAGT_L003


title: Hepatoblast_1_03


title: E13_FJW161012003_E04

description: EWF-E13_FJW161012003_E04_TCCTGAG-AAGGAGT_L003


title: Hepatic_Endoderm_3_05


title: Hepatic_Endoderm_3_06


title: E13_FJW160126002_AD07


title: E13_FJW161012003_E03

description: EWF-E13_FJW161012003_E03_AGGCAGA-AAGGAGT_L003


title: E13_FJW161012003_E02

description: EWF-E13_FJW161012003_E02_CGTACTA-AAGGAGT_L003


title: Hepatic_Endoderm_3_04


title: E13_FJW161012003_E01

description: EWF-E13_FJW161012003_E01_TAAGGCG-AAGGAGT_L003


title: E13_FJW161012003_D12

description: EWF-E13_FJW161012003_D12_ATCTCAG-ACTGCAT_L003


title: E13_FJW160126002_AD08


title: Hepatic_Endoderm_3_03


title: E13_FJW160126002_AD09


title: E13_FJW160126002_AD06


title: E13_FJW160126002_AD05


title: E13_FJW161012003_D09

description: EWF-E13_FJW161012003_D09_AAGAGGC-ACTGCAT_L003


title: E13_FJW161012003_D06

description: EWF-E13_FJW161012003_D06_TAGGCAT-ACTGCAT_L003


title: E13_FJW161012003_E08

description: EWF-E13_FJW161012003_E08_CGAGGCT-AAGGAGT_L003


title: E13_FJW161012003_D08

description: EWF-E13_FJW161012003_D08_CGAGGCT-ACTGCAT_L003


title: E13_FJW160126002_AD04


title: Hepatic_Endoderm_3_02


title: E13_FJW161012003_D05

description: EWF-E13_FJW161012003_D05_GGACTCC-ACTGCAT_L003


title: E13_FJW161012003_D07

description: EWF-E13_FJW161012003_D07_CTCTCTA-ACTGCAT_L003


title: E13_FJW161012003_D04

description: EWF-E13_FJW161012003_D04_TCCTGAG-ACTGCAT_L003


title: Hepatic_Endoderm_3_01


title: E13_FJW161012003_D11

description: EWF-E13_FJW161012003_D11_GCTCATG-ACTGCAT_L003


title: E13_FJW161012003_D10

description: EWF-E13_FJW161012003_D10_GTAGAGG-ACTGCAT_L003


title: E13_FJW161012003_D03

description: EWF-E13_FJW161012003_D03_AGGCAGA-ACTGCAT_L003


title: E13_FJW161012003_C12

description: EWF-E13_FJW161012003_C12_ATCTCAG-GTAAGGA_L003


title: E13_FJW161012003_D01

description: EWF-E13_FJW161012003_D01_TAAGGCG-ACTGCAT_L003


title: E13_FJW160126002_AD03


title: E13_FJW161012003_C11

description: EWF-E13_FJW161012003_C11_GCTCATG-GTAAGGA_L003


title: E13_FJW160126002_AD02


title: E13_FJW161012003_C09

description: EWF-E13_FJW161012003_C09_AAGAGGC-GTAAGGA_L003


title: Hepatic_Endoderm_2_21


title: E13_FJW160126002_AD01


title: E13_FJW160126002_AC12


title: E13_FJW161012003_C08

description: EWF-E13_FJW161012003_C08_CGAGGCT-GTAAGGA_L003


title: E13_FJW161012003_C10

description: EWF-E13_FJW161012003_C10_GTAGAGG-GTAAGGA_L003


title: E13_FJW161012003_C07

description: EWF-E13_FJW161012003_C07_CTCTCTA-GTAAGGA_L003


title: Hepatic_Endoderm_2_22


title: Hepatic_Endoderm_2_18


title: Hepatic_Endoderm_2_20


title: E13_FJW160126002_AC10


title: Hepatic_Endoderm_2_19


title: E13_FJW161012003_C05

description: EWF-E13_FJW161012003_C05_GGACTCC-GTAAGGA_L003


title: E13_FJW161012003_C06

description: EWF-E13_FJW161012003_C06_TAGGCAT-GTAAGGA_L003


title: E13_FJW160126002_AC09


title: E13_FJW161012003_C04

description: EWF-E13_FJW161012003_C04_TCCTGAG-GTAAGGA_L003


title: E13_FJW161012003_C03

description: EWF-E13_FJW161012003_C03_AGGCAGA-GTAAGGA_L003


title: E13_FJW161012003_C02

description: EWF-E13_FJW161012003_C02_CGTACTA-GTAAGGA_L003


title: E13_FJW161012003_D02

description: EWF-E13_FJW161012003_D02_CGTACTA-ACTGCAT_L003


title: Hepatic_Endoderm_2_17


title: Hepatic_Endoderm_2_16


title: E13_FJW160126002_AC08


title: E13_FJW160126002_AC11


title: E13_FJW161012003_C01

description: EWF-E13_FJW161012003_C01_TAAGGCG-GTAAGGA_L003


title: E13_FJW161012003_B12

description: EWF-E13_FJW161012003_B12_ATCTCAG-TATCCTC_L003


title: E13_FJW160126002_AC07


title: Hepatic_Endoderm_2_14


title: E13_FJW161012003_B11

description: EWF-E13_FJW161012003_B11_GCTCATG-TATCCTC_L003


title: E13_FJW161012003_B10

description: EWF-E13_FJW161012003_B10_GTAGAGG-TATCCTC_L003


title: Hepatic_Endoderm_2_13


title: E13_FJW160126002_AC05


title: Hepatic_Endoderm_2_15


title: Hepatic_Endoderm_2_12


title: E13_FJW161012003_B07

description: EWF-E13_FJW161012003_B07_CTCTCTA-TATCCTC_L003


title: E13_FJW161012003_B05

description: EWF-E13_FJW161012003_B05_GGACTCC-TATCCTC_L003


title: Hepatic_Endoderm_2_11


title: E13_FJW161012003_B09

description: EWF-E13_FJW161012003_B09_AAGAGGC-TATCCTC_L003


title: E13_FJW161012003_B04

description: EWF-E13_FJW161012003_B04_TCCTGAG-TATCCTC_L003


title: E13_FJW160126002_AC06


title: E13_FJW160126002_AC04


title: E13_FJW161012003_B08

description: EWF-E13_FJW161012003_B08_CGAGGCT-TATCCTC_L003


title: E13_FJW161012003_B03

description: EWF-E13_FJW161012003_B03_AGGCAGA-TATCCTC_L003


title: E13_FJW161012003_B02

description: EWF-E13_FJW161012003_B02_CGTACTA-TATCCTC_L003


title: Hepatic_Endoderm_2_10


title: Hepatoblast_1_05


title: E13_FJW160126002_AC02


title: Hepatic_Endoderm_2_09


title: E13_FJW160126002_AC01


title: E13_FJW161012003_A11

description: EWF-E13_FJW161012003_A11_GCTCATG-CTCTCTA_L003


title: Hepatic_Endoderm_2_08


title: E13_FJW161012003_A10

description: EWF-E13_FJW161012003_A10_GTAGAGG-CTCTCTA_L003


title: E13_FJW160126002_AB12


title: Hepatic_Endoderm_2_07


title: E13_FJW161012003_A08

description: EWF-E13_FJW161012003_A08_CGAGGCT-CTCTCTA_L003


title: Hepatic_Endoderm_2_06


title: E13_FJW161012003_A05

description: EWF-E13_FJW161012003_A05_GGACTCC-CTCTCTA_L003


title: E13_FJW160126002_AB11


title: Hepatic_Endoderm_2_05


title: E13_FJW160126002_AB09


title: E13_FJW161012003_A04

description: EWF-E13_FJW161012003_A04_TCCTGAG-CTCTCTA_L003


title: E13_FJW160126002_AC03


title: E13_FJW161012003_B01

description: EWF-E13_FJW161012003_B01_TAAGGCG-TATCCTC_L003


title: E13_FJW160126002_AB10


title: E13_FJW160126002_AB08


title: E13_FJW161012003_A01

description: EWF-E13_FJW161012003_A01_TAAGGCG-CTCTCTA_L003


title: E13_FJW161012003_A06

description: EWF-E13_FJW161012003_A06_TAGGCAT-CTCTCTA_L003


title: E13_FJW161012003_A07

description: EWF-E13_FJW161012003_A07_CTCTCTA-CTCTCTA_L003


title: E13_FJW161012003_A03

description: EWF-E13_FJW161012003_A03_AGGCAGA-CTCTCTA_L003


title: E13_FJW161012003_A02

description: EWF-E13_FJW161012003_A02_CGTACTA-CTCTCTA_L003


title: E13_FJW161012002_H12

description: EWF-E13_FJW161012002_H12_TCGACGT-TTATGCG_L002


title: E13_FJW161012002_H11

description: EWF-E13_FJW161012002_H11_TGCAGCT-TTATGCG_L002


title: Hepatic_Endoderm_2_03


title: E13_FJW160126002_AB07


title: E13_FJW161012002_H10

description: EWF-E13_FJW161012002_H10_CGATCAG-TTATGCG_L002


title: E13_FJW161012003_A09

description: EWF-E13_FJW161012003_A09_AAGAGGC-CTCTCTA_L003


title: Hepatic_Endoderm_2_02


title: E13_FJW161012002_H09

description: EWF-E13_FJW161012002_H09_CCTAAGA-TTATGCG_L002


title: E13_FJW160126002_AB06


title: Hepatic_Endoderm_2_04


title: E13_FJW161012002_H08

description: EWF-E13_FJW161012002_H08_ACTGAGC-TTATGCG_L002


title: Hepatic_Endoderm_2_01


title: E13_FJW161012002_H07

description: EWF-E13_FJW161012002_H07_TAGCGCT-TTATGCG_L002


title: Hepatic_Endoderm_1_29


title: E13_FJW160126002_AB04


title: E13_FJW161012002_H03

description: EWF-E13_FJW161012002_H03_GCGTAGT-TTATGCG_L002


title: Hepatoblast_1_06


title: E13_FJW161012002_H01

description: EWF-E13_FJW161012002_H01_ACTCGCT-TTATGCG_L002


title: E13_FJW161012002_H05

description: EWF-E13_FJW161012002_H05_TACGCTG-TTATGCG_L002


title: E13_FJW160126002_AB05


title: E13_FJW161012002_G12

description: EWF-E13_FJW161012002_G12_TCGACGT-GAGCCTT_L002


title: E13_FJW161012002_H02

description: EWF-E13_FJW161012002_H02_GGAGCTA-TTATGCG_L002


title: E13_FJW160126002_AB02


title: Hepatic_Endoderm_1_28


title: Hepatic_Endoderm_1_27


title: Hepatic_Endoderm_1_26


title: E13_FJW161012002_G10

description: EWF-E13_FJW161012002_G10_CGATCAG-GAGCCTT_L002


title: E13_FJW161012002_G11

description: EWF-E13_FJW161012002_G11_TGCAGCT-GAGCCTT_L002


title: E13_FJW160126002_AB01


title: Hepatic_Endoderm_1_25


title: RNA sequencing Rabbit3-Spleen biological replicate 3

city: Chengdu

first: jin

last: long

address: Hui ming

institute: Sichuan Agricultural University

description:
Rabbit3-Spleen
rabbit_exp.txt

data_processing:
Gene-level expression was estimated as transcripts per million (TPM) using the high-speed transcript quantification tool Kallisto (version 0.43.0).
Genome_build: Felis_catus_6.2, Gallus_gallus-5.0, CanFam3.1, Cavpor3.0, Mmul_8.0.1, GRCm38.p5, OryCun2.0, Rnor_6.0, Oar_v3.1
Supplementary_files_format_and_content: genes expression level (TPM) text file

organism: Oryctolagus cuniculus

source_name: Spleen

extract_protocol:
Total RNA was extracted using the RNeasy Mini Kit (Qiagen).
We used an rRNA depletion protocol (Ribo-Zero kit, Epicentre) coupled with the Illumina TruSeq stranded RNA-Seq library protocol to construct the RNA-Seq libraries. All libraries were quantified using the Qubit dsDNA High Sensitivity Assay Kit (Invitrogen) and sequenced on HiSeq X Ten (Illumina) platform to produce average ~ 49 million 150-bp paired-end raw reads and ~ 48 million high-quality reads for each library.

tag: breed

value: Japanese big-ear white rabbit

tag: tissue

value: Spleen

tag: age

value: Adult

tag: Sex

value: female


title: E13_FJW160126002_AA11

tag: cell type


title: E13_FJW161012002_G09

description: EWF-E13_FJW161012002_G09_CCTAAGA-GAGCCTT_L002


title: RNA sequencing Rabbit3-Skeletal-muscle biological replicate 3

description:
Rabbit3-Skeletal-muscle
rabbit_exp.txt

source_name: Skeletal muscle

value: Skeletal muscle


title: Hepatic_Endoderm_1_24


title: E13_FJW160126002_AA10


title: E13_FJW161012002_G08

description: EWF-E13_FJW161012002_G08_ACTGAGC-GAGCCTT_L002


title: E13_FJW161012002_H04

description: EWF-E13_FJW161012002_H04_CGGAGCC-TTATGCG_L002


title: E13_FJW161012002_H06

description: EWF-E13_FJW161012002_H06_ATGCGCA-TTATGCG_L002


title: E13_FJW160126002_AB03


title: Hepatic_Endoderm_1_23


title: RNA sequencing Rabbit3-Lung biological replicate 3

description:
Rabbit3-Lung
rabbit_exp.txt

source_name: Lung

value: Lung


title: E13_FJW161012002_G07

description: EWF-E13_FJW161012002_G07_TAGCGCT-GAGCCTT_L002


title: E13_FJW161012002_G06

description: EWF-E13_FJW161012002_G06_ATGCGCA-GAGCCTT_L002


title: Hepatic_Endoderm_1_22

source_name: EnSC


title: RNA sequencing Rabbit3-Liver biological replicate 3

description:
Rabbit3-Liver
rabbit_exp.txt

value: Liver


title: E13_FJW160126002_AA09

value: whisker follicles cells


title: E13_FJW160126002_AA07

value: ok


title: Hepatic_Endoderm_1_21


title: Hepatic_Endoderm_1_20


title: Hepatic_Endoderm_1_19


title: RNA sequencing Rabbit3-Adipose biological replicate 3

description:
Rabbit3-Adipose
rabbit_exp.txt

source_name: Adipose

value: Adipose


title: RNA sequencing Rabbit2-Spleen biological replicate 2

description:
Rabbit2-Spleen
rabbit_exp.txt


title: RNA sequencing Rabbit2-Skeletal-muscle biological replicate 2

description:
Rabbit2-Skeletal-muscle
rabbit_exp.txt


title: E13_FJW161012002_G03

description: EWF-E13_FJW161012002_G03_GCGTAGT-GAGCCTT_L002


title: Hepatic_Endoderm_1_18


title: E13_FJW160126002_AA05


title: E13_FJW160126002_AA04


title: E13_FJW161012002_G02

description: EWF-E13_FJW161012002_G02_GGAGCTA-GAGCCTT_L002


title: Hepatic_Endoderm_1_17


title: E13_FJW160126002_AA03


title: E13_FJW161012003_B06

description: EWF-E13_FJW161012003_B06_TAGGCAT-TATCCTC_L003


title: Hepatic_Endoderm_1_16


title: RNA sequencing Rabbit2-Lung biological replicate 2

description:
Rabbit2-Lung
rabbit_exp.txt


title: E13_FJW160126002_AA08


title: E13_FJW161012002_G01

description: EWF-E13_FJW161012002_G01_ACTCGCT-GAGCCTT_L002


title: E13_FJW161012002_F12

description: EWF-E13_FJW161012002_F12_TCGACGT-AAGGCTA_L002


title: E13_FJW161012002_G05

description: EWF-E13_FJW161012002_G05_TACGCTG-GAGCCTT_L002


title: Hepatic_Endoderm_1_15


title: RNA sequencing Rabbit2-Liver biological replicate 2

description:
Rabbit2-Liver
rabbit_exp.txt


title: E13_FJW160126002_AA01


title: Hepatic_Endoderm_1_14


title: RNA sequencing Rabbit3-Kidney biological replicate 3

description:
Rabbit3-Kidney
rabbit_exp.txt

source_name: Kidney

value: Kidney


title: E13_FJW161012002_G04

description: EWF-E13_FJW161012002_G04_CGGAGCC-GAGCCTT_L002


title: RNA sequencing Rabbit2-Kidney biological replicate 2

description:
Rabbit2-Kidney
rabbit_exp.txt


title: E13_FJW160126002_AA06

value: low


title: RNA sequencing Rabbit2-Heart biological replicate 2

description:
Rabbit2-Heart
rabbit_exp.txt

source_name: Heart

value: Heart


title: Hepatic_Endoderm_1_13


title: E12_FJW160809004_BH12

source_name: E12.0_whisker follicles cells


title: RNA sequencing Rabbit2-Adipose biological replicate 2

description:
Rabbit2-Adipose
rabbit_exp.txt


title: E13_FJW161012002_F09

description: EWF-E13_FJW161012002_F09_CCTAAGA-AAGGCTA_L002


title: E12_FJW160809004_BH11


title: Hepatic_Endoderm_1_12


title: RNA sequencing Rabbit1-Spleen biological replicate 1

description:
Rabbit1-Spleen
rabbit_exp.txt


title: E12_FJW160809004_BH09


title: Hepatic_Endoderm_1_11


title: E13_FJW161012002_F08

description: EWF-E13_FJW161012002_F08_ACTGAGC-AAGGCTA_L002


title: E13_FJW161012002_F07

description: EWF-E13_FJW161012002_F07_TAGCGCT-AAGGCTA_L002


title: E13_FJW160126002_AA02


title: E12_FJW160809004_BH07


title: RNA sequencing Rabbit1-Skeletal-muscle biological replicate 1

description:
Rabbit1-Skeletal-muscle
rabbit_exp.txt


title: Hepatic_Endoderm_1_10


title: E13_FJW161012002_F11

description: EWF-E13_FJW161012002_F11_TGCAGCT-AAGGCTA_L002


title: RNA sequencing Rabbit1-Lung biological replicate 1

description:
Rabbit1-Lung
rabbit_exp.txt


title: RNA sequencing Rabbit1-Kidney biological replicate 1

description:
Rabbit1-Kidney
rabbit_exp.txt


title: Hepatic_Endoderm_1_08


title: E13_FJW161012002_F05

description: EWF-E13_FJW161012002_F05_TACGCTG-AAGGCTA_L002


title: Hepatic_Endoderm_1_09


title: Hepatic_Endoderm_1_07


title: E13_FJW161012002_F10

description: EWF-E13_FJW161012002_F10_CGATCAG-AAGGCTA_L002


title: RNA sequencing Rabbit1-Heart biological replicate 1

description:
Rabbit1-Heart
rabbit_exp.txt


title: Hepatic_Endoderm_1_06


title: E12_FJW160809004_BH02


title: E13_FJW161012002_F03

description: EWF-E13_FJW161012002_F03_GCGTAGT-AAGGCTA_L002


title: E13_FJW161012002_F02

description: EWF-E13_FJW161012002_F02_GGAGCTA-AAGGCTA_L002


title: Hepatic_Endoderm_1_05


title: RNA sequencing Rabbit1-Adipose biological replicate 1

description:
Rabbit1-Adipose
rabbit_exp.txt


title: E13_FJW161012002_F01

description: EWF-E13_FJW161012002_F01_ACTCGCT-AAGGCTA_L002


title: E12_FJW160809004_BH01


title: E12_FJW160809004_BH05


title: Hepatic_Endoderm_1_04


title: RNA sequencing Rabbit1-Liver biological replicate 1

description:
Rabbit1-Liver
rabbit_exp.txt


title: Hepatic_Endoderm_1_03


title: E13_FJW161012002_E12

description: EWF-E13_FJW161012002_E12_TCGACGT-CTATTAA_L002


title: E12_FJW160809004_BH06


title: E12_FJW160809004_BG12


title: E12_FJW160809004_BG11


title: Hepatic_Endoderm_1_02


title: E13_FJW161012002_E11

description: EWF-E13_FJW161012002_E11_TGCAGCT-CTATTAA_L002


title: E13_FJW161012002_F06

description: EWF-E13_FJW161012002_F06_ATGCGCA-AAGGCTA_L002


title: E12_FJW160809004_BH03


title: E13_FJW161012002_E10

description: EWF-E13_FJW161012002_E10_CGATCAG-CTATTAA_L002


title: E12_FJW160809004_BG10


title: Hepatic_Endoderm_1_01


title: Endoderm_Stem_Cell_1_24

value: Endoderm stem cell (EnSC)


title: E13_FJW161012002_F04

description: EWF-E13_FJW161012002_F04_CGGAGCC-AAGGCTA_L002


title: CAR KO rat, 1000 ppm PB for 7 days, biological rep3

type: RNA

city: Osaka

first: Ayako

last: Ohara

address: 1-98, Kasugade-naka 3-chome, Konohana-ku

institute: Sumitomo Chemical Co., Ltd.

description: gene expression data from liver of CAR KO rat fed diets containing 1000 ppm PB for 7 days

hyb_protocol: 600 ng of Cy3-labelled cRNA (specific activity >10.0 pmol Cy3/ug cRNA) was fragmented at 60°C for 30 minutes using the Gene Expression Hybridization Kit (Agilent) following the manufacturers instructions. On completion of the fragmentation reaction, mixtures were hybridized to SurePrint G3 Rat Gene Expression 8x60K Microarrays, SurePrint G3 Mouse GE 8x60K Microarrays or SurePrint G3 Human GE v2 8x60K Microarrays for 17 hours at 65°C in a rotating hybridization oven.  After hybridization, microarrays were washed 1 minute at room temperature with GE Wash Buffer 1 (Agilent) and 1 minute with 37°C GE Wash buffer 2 (Agilent), then dried immediately by brief centrifugation.

scan_protocol: Slides were scanned immediately after washing on the Agilent DNA Microarray Scanner (Agilent) using one color scan setting for 8x60K array slides. The scanned images were analyzed with Feature Extraction Software 10.7.3.1 (Agilent) to obtain background subtracted and spatially detrended Processed Signal intensities. Features flagged in Feature Extraction as Feature Non-uniform outliers were excluded.

data_processing: The processed signal intensities were log2-transformed and normalized to the 75th percentile using GeneSpring software (version 14.9.1) (Agilent).

organism: Rattus norvegicus

label_protocol: Cyanine-3 (Cy3) labeled cRNA was prepared from 100 ng RNA using the Low Input Quick Amp Labeling Kit, one-color (Agilent) according to the manufacturer's instructions. Dye incorporation and cRNA yield were checked with the NanoDrop 2000/2000c Spectrophotometer.

growth_protocol: The animals were housed in a barrier maintained animal room. The environmental conditions in the animal room were set to maintain a temperature range of 22 - 26°C and a relative humidity range of 40 - 70%, and a 12 hour light (8:00 - 20:00)/ 12 hour dark (20:00 - 8:00) illumination cycle. A commercially available pulverized diet and filtered tap water were provided ad libitum.

extract_protocol: The livers were stored in RNAlater RNA Stabilization Reagent (Life Technologies Corporation, Carlsbad, CA) at -20°C. Total RNA was prepared using Isogen solution (Nippon Gene) and RNeasy Mini Kits (Qiagen) following the manufacturer's instructions. Total RNA was quantified using a NanoDrop 2000/2000c Spectrophotometer (Thermo Fisher Scientific, Waltham, MA) and quality was monitored with the Agilent 2100 Bioanalyzer (Agilent Technologies, Santa Clara, CA).

treatment_protocol: Male chimeric mice with rat hepatocytes, Crl:CD(SD) rats and CAR KO rats (4-7 animals/dose) were fed diets containing 0 (control) or 1000 ppm PB for 7 days.

tag: gender

value: male

value: liver


title: E12_FJW160809004_BG09


title: E13_FJW161012002_E09

description: EWF-E13_FJW161012002_E09_CCTAAGA-CTATTAA_L002


title: CAR KO rat, 1000 ppm PB for 7 days, biological rep4

source_name: liver of CAR KO rat fed diets containing 1000 ppm PB for 7 days


title: E12_FJW160809004_BG08


title: E13_FJW161012002_E08

description: EWF-E13_FJW161012002_E08_ACTGAGC-CTATTAA_L002


title: CAR KO rat, 1000 ppm PB for 7 days, biological rep2


title: Endoderm_Stem_Cell_1_23


title: Endoderm_Stem_Cell_1_22


title: CAR KO rat, 0 ppm (control) for 7 days, biological rep4

description: gene expression data from liver of CAR KO rat fed diets containing 0 ppm (control) for 7 days


title: E13_FJW161012002_E07

description: EWF-E13_FJW161012002_E07_TAGCGCT-CTATTAA_L002


title: E12_FJW160809004_BG06


title: E13_FJW161012002_E06

description: EWF-E13_FJW161012002_E06_ATGCGCA-CTATTAA_L002


title: Endoderm_Stem_Cell_1_21


title: E12_FJW160809004_BG05


title: E13_FJW161012002_E05

description: EWF-E13_FJW161012002_E05_TACGCTG-CTATTAA_L002


title: Endoderm_Stem_Cell_1_20


title: E12_FJW160809004_BH04


title: E12_FJW160809004_BG03


title: E13_FJW161012002_E04

description: EWF-E13_FJW161012002_E04_CGGAGCC-CTATTAA_L002


title: E12_FJW160809004_BG04


title: Endoderm_Stem_Cell_1_19


title: CAR KO rat, 0 ppm (control) for 7 days, biological rep3

source_name: liver of CAR KO rat fed diets containing 0 ppm (control) for 7 days


title: E12_FJW160809004_BG02


title: E13_FJW161012002_E03

description: EWF-E13_FJW161012002_E03_GCGTAGT-CTATTAA_L002


title: CAR KO rat, 0 ppm (control) for 7 days, biological rep2


title: Endoderm_Stem_Cell_1_18


title: E13_FJW161012002_E02

description: EWF-E13_FJW161012002_E02_GGAGCTA-CTATTAA_L002


title: SD rat, 1000 ppm PB for 7 days, biological rep3

description: gene expression data from liver of SD rat fed diets containing 1000 ppm PB for 7 days


title: CAR KO rat, 0 ppm (control) for 7 days, biological rep1


title: Endoderm_Stem_Cell_1_17


title: E12_FJW160809004_BF12


title: Endoderm_Stem_Cell_1_16


title: E13_FJW161012002_E01

description: EWF-E13_FJW161012002_E01_ACTCGCT-CTATTAA_L002


title: E12_FJW160809004_BF11


title: E13_FJW161012002_D12

description: EWF-E13_FJW161012002_D12_TCGACGT-GCGTAAG_L002


title: SD rat, 1000 ppm PB for 7 days, biological rep2

source_name: liver of SD rat fed diets containing 1000 ppm PB for 7 days


title: E13_FJW161012002_D11

description: EWF-E13_FJW161012002_D11_TGCAGCT-GCGTAAG_L002


title: CAR KO rat, 1000 ppm PB for 7 days, biological rep1


title: SD rat, 1000 ppm PB for 7 days, biological rep4


title: SD rat, 1000 ppm PB for 7 days, biological rep1


title: Endoderm_Stem_Cell_1_15


title: E12_FJW160809004_BF10


title: E13_FJW161012002_D10

description: EWF-E13_FJW161012002_D10_CGATCAG-GCGTAAG_L002


title: Endoderm_Stem_Cell_1_14


title: E12_FJW160809004_BF09


title: SD rat, 0 ppm (control) for 7 days, biological rep4

description: gene expression data from liver of SD rat fed diets containing 0 ppm (control) for 7 days


title: E12_FJW160809004_BG01


title: Endoderm_Stem_Cell_1_13


title: SD rat, 0 ppm (control) for 7 days, biological rep3

source_name: liver of SD rat fed diets containing 0 ppm (control) for 7 days


title: E13_FJW161012002_D09

description: EWF-E13_FJW161012002_D09_CCTAAGA-GCGTAAG_L002


title: SD rat, 0 ppm (control) for 7 days, biological rep2


title: E13_FJW161012002_D08

description: EWF-E13_FJW161012002_D08_ACTGAGC-GCGTAAG_L002


title: E12_FJW160809004_BF07


title: E12_FJW160809004_BF08


title: E13_FJW161012002_D07

description: EWF-E13_FJW161012002_D07_TAGCGCT-GCGTAAG_L002


title: Endoderm_Stem_Cell_1_10


title: SD rat, 0 ppm (control) for 7 days, biological rep1


title: E12_FJW160809004_BF05


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep7

description: gene expression data from liver of chimeric mouse with rat hepatocytes fed diets containing 1000 ppm PB for 7 days


title: Endoderm_Stem_Cell_1_12


title: Endoderm_Stem_Cell_1_09


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep6

source_name: liver of chimeric mouse with rat hepatocytes fed diets containing 1000 ppm PB for 7 days


title: Endoderm_Stem_Cell_1_08


title: Endoderm_Stem_Cell_1_07


title: E13_FJW161012002_D04

description: EWF-E13_FJW161012002_D04_CGGAGCC-GCGTAAG_L002


title: E12_FJW160809004_BF04


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep4


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep5


title: E13_FJW161012002_D03

description: EWF-E13_FJW161012002_D03_GCGTAGT-GCGTAAG_L002


title: E12_FJW160809004_BF02


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep3


title: Endoderm_Stem_Cell_1_06


title: Endoderm_Stem_Cell_1_11


title: E12_FJW160809004_BF06


title: E12_FJW160809004_BF01


title: E13_FJW161012002_D02

description: EWF-E13_FJW161012002_D02_GGAGCTA-GCGTAAG_L002


title: E13_FJW161012002_D01

description: EWF-E13_FJW161012002_D01_ACTCGCT-GCGTAAG_L002


title: E13_FJW161012002_D05

description: EWF-E13_FJW161012002_D05_TACGCTG-GCGTAAG_L002


title: chimeric mouse with rat hepatocytes, 0 ppm (control) for 7 days, biological rep7

description: gene expression data from liver of chimeric mouse with rat hepatocytes fed diets containing 0 ppm (control) for 7 days


title: E12_FJW160809004_BE11


title: E12_FJW160809004_BF03


title: Endoderm_Stem_Cell_1_03


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep1


title: chimeric mouse with rat hepatocytes, 0 ppm (control) for 7 days, biological rep6

source_name: liver of chimeric mouse with rat hepatocytes fed diets containing 0 ppm (control) for 7 days


title: E13_FJW161012002_C12

description: EWF-E13_FJW161012002_C12_TCGACGT-CCTAGAG_L002


title: chimeric mouse with rat hepatocytes, 1000 ppm PB for 7 days, biological rep2


title: E13_FJW161012002_C11

description: EWF-E13_FJW161012002_C11_TGCAGCT-CCTAGAG_L002


title: Endoderm_Stem_Cell_1_04


title: E12_FJW160809004_BE09


title: E13_FJW161012002_C10

description: EWF-E13_FJW161012002_C10_CGATCAG-CCTAGAG_L002


title: E12_FJW160809004_BE08


title: Endoderm_Stem_Cell_1_05


title: E13_FJW161012002_C09

description: EWF-E13_FJW161012002_C09_CCTAAGA-CCTAGAG_L002


title: E12_FJW160809004_BE07


title: E12_FJW160809004_BE12


title: chimeric mouse with rat hepatocytes, 0 ppm (control) for 7 days, biological rep5


title: E_hep_9_24

value: EnSC-derived hepatocyte


title: chimeric mouse with rat hepatocytes, 0 ppm (control) for 7 days, biological rep4


title: chimeric mouse with rat hepatocytes, 0 ppm (control) for 7 days, biological rep2


title: E13_FJW161012002_C08

description: EWF-E13_FJW161012002_C08_ACTGAGC-CCTAGAG_L002


title: E12_FJW160809004_BE10


title: E_hep_9_23


title: E13_FJW161012002_C07

description: EWF-E13_FJW161012002_C07_TAGCGCT-CCTAGAG_L002


title: E12_FJW160809004_BE06


title: chimeric mouse with rat hepatocytes, 0 ppm (control) for 7 days, biological rep1


title: E_hep_9_22


title: E12_FJW160809004_BE05


title: E_hep_9_21


title: E12_FJW160809004_BE04


title: E13_FJW161012002_C05

description: EWF-E13_FJW161012002_C05_TACGCTG-CCTAGAG_L002