title: LAIV_003_Curettage_Visit1


title: LAIV_007_Curettage_1

status: Public on Oct 19 2023

type: SRA

city: London

first: Ryan

last: Thwaites

state: London

address: St Mary's Hospital

country: United Kingdom

institute: Imperial College London

library_source: transcriptomic

data_processing:
Fastp (v 0.20.1) was used to trim the adapters and reads were mapped against human GRCh38 Ensembl 99
Quantification was performed using the Salmon tool
DeSEQ2 (v 1.34.0) was used to normalize the counts
Assembly: GRCh38
Supplementary files format and content: tab-delimited text files include  counts values for each Sample

molecule: total RNA

organism: Homo sapiens

source_name: nasal epithelium

extract_protocol:
Lexogen SPLIT RNA extraction kit per manufacturers protocol
Lexogen QuantSeq FWD kit per manufacturers protocol

tag: tissue

value: nasal epithelium

tag: cell type

value: Primary nasal epithelial

tag: time point

value: Baseline


title: LAIV_003_Curettage_4


title: LAIV_023_Curettage_4


title: LAIV_002_Curettage_1


title: LAIV_017_Curettage_1


title: LAIV_012_Curettage_1


title: LAIV_011_Curettage_4


title: LAIV_001_Curettage_4


title: IMR32_siG9a_MYCN

city: Bethesda

first: Zhihui

last: Liu

state: Maryland

address: 9000 rockville pike

country: USA

institute: National Cancer Institute

library_source: genomic

data_processing:
Basecalls performed using CASAVA version 1.4
ChIP-seq reads were aligned to the hg19 genome using bwa and then use the MACS2 for peak calling
Assembly: hg19
Supplementary files format and content: bigWig files were generated using deeptools. The coverage is calculated as the number of reads per bin.

molecule: genomic DNA

growth_protocol: IMR32 cells are maintained in growth medium. Growth medium: RPMI-1640, 10% fetal calf serum, 100µg/mL streptomycin, 100U/mL penicillin, and L-glutamine.

extract_protocol:
Lysates were clarified from sonicated nuclei and protein-DNA complexes were isolated with antibody following the Active Motif's instructions of the ChIP-IT High Sensitivity Kit.
Libraries were prepared according to Illumina's TruSeq ChIP Sample Preparation Guide.

treatment_protocol: siCtrl or siG9a was transiently transfected into IMR32 cells using Nucleofector electroporation (Lonza) and cultured in growth medium for 72 h, then ChIP experiment was performed.

tag: cell line

value: Neuroblastoma

tag: treatment

tag: chip antibody

value: MYCN (Active motif, 61185)


title: IMR32_siControl_input_14

source_name: Input DNA

treatment_protocol: siCtrl or siWDR5 was transiently transfected into IMR32 cells using Nucleofector electroporation (Lonza) and cultured in growth medium for 72 h, then ChIP experiment was performed.

value: siCtrl

value: No


title: IMR32_siMYCN_H3K4me1

treatment_protocol: siCtrl or siMYCN was transiently transfected into IMR32 cells using Nucleofector electroporation (Lonza) and cultured in growth medium for 72 h, then ChIP experiment was performed.

value: IMR32 cells

value: siMYCN

value: H3K4me1 (Active motif, 39297)


title: IMR32_siWDR5_input_17


title: IMR32_siControl_WDR5_10

value: WDR5 (Bethyl, A302-429A)


title: IMR32_siWDR5_MYCN_4


title: IMR32_siG9a_input


title: IMR32_siWDR5_WDR5_11


title: IMR32_siMYCN_WDR5


title: IMR32_siControl_MYCN_1


title: IMR32_siCtrl_H3K4me1


title: IMR32_siMYCN_H3K27ac

value: H3K27ac (Active motif, 39133)


title: IMR32_siControl_input


title: IMR32_siControl_MYCN


title: IMR32_siCtrl_WDR5


title: IMR32_siCtrl_H3K27ac


title: IMR32_siMYCN_H3K4me3


title: IMR32_siMYCN_H3K27me3

value: H3K27me3 (Millipore, 07-449)


title: IMR32_siCtrl_H3K27me3


title: IMR32_siMYCN_G9a_pooled


title: IMR32_siCtrl_G9a_pooled


title: IMR32_siMYCN_MYCN


title: IMR32_siCtrl_H3K4me3


title: IMR32_siCtrl_MYCN


title: IMR32_siCtrl_input


title: IMR32_siMYCN_input


title: CD8+ T cell, Spleen, Naïve, replicate 1

city: New York

first: Vivek

last: Mittal

state: NY

address: 525 East 68th Street, W412

department: Cardiothoracic Surgery

institute: Weill Cornell Medicine

data_processing:
Tophat v2.0.11 was used to align raw sequencing reads to the mm9 mouse reference genome.
Cufflinks v2.1.1 was used to measure transcript abundances in Fragments Per Kilobase of exon model per Million mapped reads (FPKM) with upper-quartile normalization and sequence-specific bias correction.
Raw read counts per gene were extracted using HTSeq-count v0.6.1
Assembly: mm9
Supplementary files format and content: expression.genes.no_NR.xls (FPKM using Cufflinks)
Supplementary files format and content: raw_counts_genes.txt (raw read counts using HTSeq-count)

organism: Mus musculus

source_name: Spleen

growth_protocol: HKP1 cells for tumor generation were cultured in DMEM supplemented with 10% FBS, 100 U/mL penicillin with 100μg/mL streptomycin, and 2mM L-glutamine and stored in a humidified incubator at 37℃, 5% CO2.

extract_protocol:
RNA in RLT lysis buffer supplemented with β-mercaptoethanol was thawed from -80℃ and subsequently isolated using RNeasy Mini Kits (Qiagen) with on-column DNA digestion as per the manufacturer’s protocols.
PolyA+ Selection, Illumina TruSeq Stranded Total RNA Sample Preparation as per the manufacturer's protocols.

treatment_protocol: Mice received orthotopic implantation of HKP1 tumor cells via tail vein injections. At specified time points, mice were euthanized and perfused with PBS. Lungs were then dissected, diced, and ground through a 140μm wire mesh into Complete T Cell Media (Advanced RPMI (RPMI-1640 with non-essential amino acids and 110mg/L sodium pyruvate) supplemented with 10% FBS, 100 U/mL penicillin with 100μg/mL streptomycin, 2mM GlutaMAX, 10mM HEPES, and 50μM β-mercaptoethanol) . Single-cell suspensions were subsequently filtered through 70μm filters and centrifuged for 5 minutes at 1500 rpm. Cell pellets were resuspended in 1mL ACK Lysing Buffer for one minute for red blood cell lysis, neutralized with 9mL Complete T Cell Media, and centrifuged for 5 minutes at 1500 rpm. Cell pellets were washed once with FACS Buffer, centrifuged for 5 minutes at 1500 rpm, and resuspended in FACS Buffer. Samples were subsequently blocked with anti-mouse CD16/32 for 15 minutes at room temperature, incubated with primary antibodies for CD11c, MHC-II, CD45, TCRβ, CD4, and CD8β for 30 minutes on ice in the dark, washed with FACS Buffer, stained with DAPI for 10 minutes at 0.2μg/mL, washed with FACS Buffer, and resuspended in FACS Buffer. Samples were sorted on a Becton-Dickinson FACS Aria II sorter. DAPI- TCRβ+ CD4- CD8β+ were sorted into RLT lysis buffer supplemented with β-mercaptoethanol, and frozen at -80℃ until RNA extraction.

value: Spleen

tag: timepoint

value: Naïve

value: CD8+ T cell

tag: genotype

value: WT from C57BL/6

tag: group

value: Naive


title: CD8+ T cell, Spleen, Naïve, replicate 2


title: CD8+ T cell, Spleen, Naïve, replicate 3


title: CD8+ T cell, Spleen, Low, Day 24, replicate 3

value: Day 24

value: Low


title: CD8+ T cell, Spleen, Low, Day 24, replicate 2


title: CD8+ T cell, Spleen, High, Day 24, replicate 1

value: High


title: CD8+ T cell, Spleen, Low, Day 24, replicate 1


title: CD8+ T cell, Spleen, High, Day 17, replicate 3

value: Day 17


title: CD8+ T cell, Spleen, High, Day 17, replicate 2


title: CD8+ T cell, Spleen, Day 7, replicate 6

value: Day 7


title: CD8+ T cell, Spleen, Day 7, replicate 5


title: CD8+ T cell, Spleen, Low, Day 17, replicate 3


title: CD8+ T cell, Spleen, Low, Day 17, replicate 2


title: CD8+ T cell, Spleen, Day 7, replicate 4


title: CD8+ T cell, Spleen, Day 7, replicate 3


title: CD8+ T cell, Spleen, Day 7, replicate 1


title: CD8+ T cell, Spleen, Day 7, replicate 2


title: CD8+ T cell, Spleen, Low, Day 17, replicate 1


title: CD8+ T cell, Lung, Naïve, replicate 1

source_name: Lung

value: Lung


title: CD8+ T cell, Tumor-bearing lung, Low, Day 24, replicate 3

source_name: Tumor-bearing lung

value: Tumor-bearing lung


title: CD8+ T cell, Tumor-bearing lung, High, Day 17, replicate 3


title: CD8+ T cell, Tumor-bearing lung, Low, Day 24, replicate 1


title: CD8+ T cell, Tumor-bearing lung, Low, Day 24, replicate 2


title: CD8+ T cell, Lung, Naïve, replicate 2


title: CD8+ T cell, Tumor-bearing lung, High, Day 24, replicate 1


title: CD8+ T cell, Spleen, High, Day 17, replicate 1


title: CD8+ T cell, Tumor-bearing lung, High, Day 17, replicate 2


title: CD8+ T cell, Lung, Naïve, replicate 3


title: CD8+ T cell, Spleen, High, Day 24, replicate 2


title: CD8+ T cell, Tumor-bearing lung, Low, Day 17, replicate 3


title: CD8+ T cell, Tumor-bearing lung, Low, Day 17, replicate 1


title: CD8+ T cell, Tumor-bearing lung, Low, Day 17, replicate 2


title: CD8+ T cell, Tumor-bearing lung, Day 7, replicate 5


title: CD8+ T cell, Tumor-bearing lung, High, Day 17, replicate 1


title: CD8+ T cell, Tumor-bearing lung, Day 7, replicate 6


title: CD8+ T cell, Tumor-bearing lung, Day 7, replicate 2


title: CD8+ T cell, Tumor-bearing lung, Day 7, replicate 4


title: CD8+ T cell, Tumor-bearing lung, Day 7, replicate 1


title: Amplicon seq, control, rep2

city: Stanford

first: Shuai

last: Wang

state: CA

address: 265 Campus Drive

institute: Stanford University

description:
sampleID: 2
amplicon of PBM region of Lphn3 mRNA
amplicon_paired_seq_PBMKOed.csv

library_source: other

data_processing:
STAR (2.7.10b) for alignment
Custom python (3.11.4) scripts for analysing PBM KO efficiency
Assembly: GRCm38/mm10
Supplementary files format and content: amplicon_paired_seq_PBMKOed.csv: PBM KO efficiency analysis for each paired-read
Library strategy: Amplicon Sequencing

source_name: neuron

growth_protocol: Neonatal P0 mice pups of CAG-cas9 mice (JAX #024858) were dissected in ice cold HBS to obtain hippocampi, which were digested in 1% v/v papain suspension (Worthington) and 0.1 U/µl DNaseI (Worthington) DNaseI for 15min at 37˚C. Hippocampi from 2 pups were washing with calcium-free 1xHBS  (pH7.3) and dissociated using gentle pipetting in plating medium (MEM containing 5% FBS, 0.6% glucose, 2% Gem21 NeuroPlex™ Supplement, 2 mM GlutaMAX™), filtered through 70 µm cell strainer, and seeded onto Corning® Matrigel®-coated 12 mm cover glasses in one 24-well plate, and maintained at 37˚C 5% CO2. 16 hr post seeding (DIV1), 90% media were replaced by maintenance medium (Neurobasal A with 2% Gem21 NeuroPlex™ Supplement, 2 mM GlutaMAX™). At DIV 3, 50% of medium were replaced with fresh maintenance medium supplemented 4 µM Ara-C (Cytosine β-D-arabinofuranoside hydrochloride), and lentivirus expressing gRNA. At DIV7, 10, and 13, 30% media were replaced with fresh maintenance medium, before analyzing at DIV14.

extract_protocol:
Total RNA from cultured neurons were extracted by TRIzol®, converted to cDNA using Takara PrimeScript  Reverse Transcriptase
cDNAs were converted to amplicons using primers flanking PBM region of Lphn3, using Illumina Nextera XT adaptors and NEB Q5 polymerase.

treatment_protocol: Neurons were infected with lentiviruese expressing indicated gRNA at DIV3

value: neuron

value: lentivirus expressing control gRNA


title: CD8+ T cell, Tumor-bearing lung, High, Day 24, replicate 2


title: Amplicon seq, control, rep1

description:
sampleID: 1
amplicon of PBM region of Lphn3 mRNA
amplicon_paired_seq_PBMKOed.csv


title: 13_WT_Wake

city: Jerusalem

first: Miriam

last: Adam

state: Israel

address: Givat Ram

country: Israel

institute: The Hebrew University of Jerusalem

description: 10x Genomics

library_source: transcriptomic single cell

data_processing:
Demultiplexing, cell calling and gene counting were done using the Cell Ranger software v 5.0.0.
Assembly: mm10
Supplementary files format and content: tab separated files with barodes and features. Matrix files

molecule: polyA RNA

source_name: Hippocampus

extract_protocol:
Nuclei were isolated from frozen hippocampus tissues. Samples were homogenized in lysis buffer (10 mM Tris HCL pH 7.5, 10 mM NaCl, 3 mM MgCl2, 0.1% NP-40, 40 U/mL of RNAse inhibitor ) followed by spin down at 500xf for 5min at 4°C. The supernatant was removed, and the pellets were resuspended in 5ml wash buffer (PBS, 1% BSA, 40U/mL of RNAse inhibitors) and centrifuged again at 500g for 5 mins at 4°C. The supernatant was removed and the pellet was gently resuspended in 250 μL of wash buffer. Nuclei were filtered through a 30 μm filter and counted.
GEM generation and libarary construction were done according to manufacturer instructions of 10x Genomics Chromium Single Cell 3' Reagent Kit (v3.1 Chemistry)

treatment_protocol: 4.5-5.5 month-old male APP/PS1 (APPSwe/PS1ΔE9) and their wild-type littermates were anesthetized  with Isoflurane (5% reduced to 1.5% over time) or with Ketamine  xylazine (150 mg/kg ketamine and 12 mg/kg. Mice were  sacrificed immediately after 3 hours of anesthesia. Tissue was collected after transcardial  perfusion with cold PBS. Hippocampus was dissected, snap-frozen in liquid nitrogen, and  stored at 80C until further processing xylazine)

value: Hippocampus

value: WT

value: Wake


title: 17_APP/PS1_Wake

description: 10x Genomics


title: 25_APP/PS1_Ketamine

description: 10x Genomics

value: Ketamine


title: 29_WT_Wake

description: 10x Genomics


title: 26_APP/PS1_Ketamine

description: 10x Genomics


title: 19_WT_Wake

description: 10x Genomics


title: 20_APP/PS1_Isofluran

description: 10x Genomics

value: Isofluran


title: 16_WT_Isofluran

description: 10x Genomics


title: 28_WT_Ketamine

description: 10x Genomics


title: 18_WT_Isofluran

description: 10x Genomics


title: 12_WT_Wake

description: 10x Genomics


title: Amplicon seq, PBM KO, rep2

description:
sampleID: 6
amplicon of PBM region of Lphn3 mRNA
amplicon_paired_seq_PBMKOed.csv

value: lentivirus expressing PBM KO gRNA


title: 11_APP/PS1_Isofluran

description: 10x Genomics


title: CD8+ T cell, Tumor-bearing lung, Day 7, replicate 3

value: CD8+ T cell

value: WT from C57BL/6


title: 27_WT_Ketamine

description: 10x Genomics


title: Amplicon seq, PBM KO, rep1

description:
sampleID: 5
amplicon of PBM region of Lphn3 mRNA
amplicon_paired_seq_PBMKOed.csv


title: 10_APP/PS1_Wake

description: 10x Genomics


title: 4_APP/PS1_Isofluran

description: 10x Genomics


title: 3_WT_Isofluran

description: 10x Genomics


title: FloxedFull 4

city: Boston

first: Peter

last: Sage

address: 221 Longwood Ave

department: Medicine/Renal

institute: Brigham and Women's Hospital

data_processing:
Basecalling was performed using Illumina Software
Reads were aligned to the mouse genome mm10 using CLC Genomics software suite
Reads per million were generated for each sample
Assembly: mm10
Supplementary files format and content: Tab-deliminated file

source_name: LN

extract_protocol:
Lymph nodes were mashed through 70micron filters and cells were sorted
RNA libraries were constructed using previously published protocols using Illumina adaptors (Sage Nature Immunology 2016)

treatment_protocol: Ex vivo sorting

value: LN

value: FloxedFull

value: Floxed

value: NP-OVA Immunized


title: HA_Neural_H4K91R_Input

first: Douglas

last: Barrows

address: 1230 York Ave

institute: Rockefeller University

data_processing:
ChIP-seq reads were aligned using Rsubread’s align method and predicted fragment lengths were calculated by the ChIPQC R Bioconductor package. Normalized, fragment extended signal bigWigs were created using the rtracklayer R Bioconductor package. Peak calls were made using the MACS2 software.
Assembly: mm10
Supplementary files format and content: bigwig files normalized to read depth
Supplementary files format and content: narrowPeak files generated by MACS2

source_name: Neural cells

extract_protocol:
Cells were fixed with 1% paraformaldehyde for 5 minutes with gentle rotation and then quenched with 125 mM glycine for 5 minutes. After cell lysis, chromatin was sonicated using a Covaris E220. Genomic DNA was isolated after the immunoprecipitation of sonicated chromatin.
Libraries were generated using NEBNext Ultra II kits.

value: neural cells differentiated from mESCs

value: Stably expressing PiggyBAC_H4K91R_3HA


title: HA_Neural_H4K91R_ChIP

value: HA (biolegend 901501)


title: HA_Neural_H4WT_ChIP

value: Stably expressing PiggyBAC_H4WT_3HA


title: FloxedProg 3

value: FloxedProg


title: HA_Neural_EV_ChIP

value: Stably expressing PiggyBAC_Empty vector


title: ConProg 1

value: ConProg

value: WT


title: FloxedFull 3


title: FloxedFull 1


title: FloxedFull 2


title: ConFull 2

value: ConFull


title: HA_Neural_EV_Input


title: HA_NPCs_H4K91Q_ChIP

source_name: NPCs

value: mESC derived neural progenitor cells

value: Stably expressing PiggyBAC_H4K91Q_3HA


title: FloxedProg 4


title: HA_Neural_H4K91Q_Input


title: HA_NPCs_H4K91Q_Input


title: ConFull 4


title: FloxedProg 2


title: HA_Neural_H4K91Q_ChIP


title: ConFull 3


title: HA_NPCs_H4K91R_ChIP


title: ConFull 1


title: HA_NPCs_H4K91R_Input


title: HA_NPCs_EV_ChIP


title: HA_NPCs_H4WT_Input


title: HA_NPCs_EV_Input


title: HA_Neural_H4WT_Input


title: HA_DAXXKO_H4K91R_ChIP

value: mouse embryonic stem cells

tag: ablation

value: DAXXKO

value: Pierce Anti-HA magnetic beads (Thermo Fisher Scientific 88836)


title: HA_H33DKO_H4K91R_ChIP


title: HA_H33DKO_H4K91Q_ChIP


title: HA_H33DKO_H4K91Q_Input


title: HA_DAXXKO_H4K91Q_Input


title: HA_DAXXKO_H4K91Q_ChIP


title: 2_APP/PS1_Wake

description: 10x Genomics

value: Hippocampus

value: Wake


title: HA_HiraKO_H4K91R_Input

value: HiraKO


title: 1_WT_Wake

description: 10x Genomics


title: HA_parental_H4K91Q_Input

source_name: mESCs


title: HA_parental_H4K91Q_ChIP


title: HA_HiraKO_H4K91Q_Input


title: HA_NPCs_H4WT_ChIP


title: FloxedProg 1

value: LN

value: Floxed

value: NP-OVA Immunized


title: HA_HiraKO_H4K91R_ChIP

value: Stably expressing PiggyBAC_H4K91R_3HA


title: HA_H33DKO_H4K91R_Input


title: ConProg 4


title: ConProg 3


title: 14_WT_Wake

description: 10x Genomics


title: HA_parental_H4K91R_ChIP


title: HA_parental_H4K91R_Input


title: ConProg 2


title: HA_DAXXKO_H4K91R_Input


title: HA_HiraKO_H4K91Q_ChIP


title: HA_parental_EV_ChIP


title: HA_parental_H4WT_Input

value: Stably expressing PiggyBAC_H4WT_3HA


title: HA_parental_H4WT_ChIP


title: HA_parental_EV_Input

value: Stably expressing PiggyBAC_Empty vector


title: Neural_K91Q3

data_processing:
Transcript abundance was computed from FASTQ files using Salmon (v0.8.2) and the GENCODE reference transcript sequences, transcript counts were imported into R with the tximport R Bioconductor package, and differential gene expression was determined with the DESeq2 R Bioconductor package
Assembly: mm10
Supplementary files format and content: Counts tables contain the raw counts quantified by Salmon and DESeq2.

extract_protocol:
Cells were harvested, washed with PBS, and flash frozen in liquid nitrogen. RNA was isolated using QIAGEN RNeasy kit.
Libraries were generated using NEBNext Ultra II kits.

value: neural cells differentiated from mESCs


title: Neural_K91R2


title: Neural_K91Q1


title: Neural_WT3


title: Neural_K91R3


title: Neural_WT2


title: Neural_WT1


title: TFH_full_1

data_processing:
Basecalls were performed using bcl2fastq v2.17 for Novaseq output.
Quality trimming and primer removal from the raw fastq files were performed using Trimmomatic (v3.9) using the following parameters: LEADING:15 TRAILING:15 SLIDINGWINDOW:4:15 and MINLEN:36
Trimmed reads were aligned to Mm10 genome using Bowtie2 (v2.4.5) using a maximum insert size of 1,000.
PCR duplicates were marked using Picard (2.18.7).
Peak-calling was performed for each biological condition using MACS (v2.2.7.1) on merged bam files with a q-value threshold of 0.001. Consensus peaks from all biological conditions were then merged to create a single peak universe of 56,060 regions.
Cut sites were extracted from each biological replicate and the number of cuts within each peak region was quantified (BEDtools v2.30.0) to generate a raw counts matrix.
DESeq2 (v3.15) was used to normalize the counts matrix and perform differential accessibility analysis between all of the relevant comparisons.
Gene-to-peak associations were determined using the GREAT software package (v3.0.0).
ATAC-seq tracks were visualized using Integrative Genomics Viewer (v2.13.2)
Motif enrichment analysis was performed using HOMER (v3.0) with default settings.
Assembly: mm10
Supplementary files format and content: narrowPeak

source_name: VFP+ tdTom+

extract_protocol:
Sorted T cells were washed and lysed utilizing the ATAC Lysis Buffer (ATAC-Seq Kit, Active Motif).
Tagmentation and library preparation were performed according to the manufacturer’s instructions (ATAC-Seq Kit, Active Motif). Samples were pooled after indexing and sequenced on a llumina NextSeq sequencer.

treatment_protocol: Live CD4+CD19-CXCR5+GITR- cells were sorted based on VFP and TdTomato expression into Tfh-Prog (VFP-TdTomato-), Tfh-Trans (VFP+TdTomato-), Tfh-Full (VFP+TdTomato+) and Tfh-Ex (VFP-TdTomato+). Conventional T cells (CD4+CD19-CXCR5-GITR-) were also sorted as a control.

value: VFP+ tdTom+

value: Mouse CD4 T Follicular helper cell

value: ATAC-Seq Kit, Active Motif


title: Neural_K91Q2

value: Stably expressing PiggyBAC_H4K91Q_3HA


title: TFH_full_2


title: TFH_prog_2

source_name: VFP- tdTom-

value: VFP- tdTom-


title: TFH_trans_1

source_name: VFP+ tdTom-

value: VFP+ tdTom-


title: TFH_ex_1

source_name: VFP- tdTom+

value: VFP- tdTom+


title: T con_2

source_name: Mouse CD4 T  cell

value: Mouse CD4 T  cell


title: TFH_prog


title: T con_1


title: T con


title: TfhFull rep 3

value: TfhFull

value: WT


title: TFH_ex


title: TFH_trans


title: TFH_full


title: TFH_prog_1


title: TfhFull rep 2

value: LN


title: TfhProg rep 3

value: TfhProg


title: TfhFull rep 1

value: NP-OVA Immunized


title: TfhProg rep 1


title: Neural_K91R1

value: Stably expressing PiggyBAC_H4K91R_3HA


title: Tcon 21 rep 3


title: Tcon 21 rep 2


title: 15_APP/PS1_Isofluran

description: 10x Genomics

value: Hippocampus

value: Isofluran


title: Tcon 21 rep 1


title: Tcon rep 3

value: Tcon


title: Tcon rep 2


title: Tcon rep 1


title: Pdgfra-GFP PBS

city: Research Triangle Park

first: Stavros

last: Garantziotis

state: NC

address: 111 TW Alexander Drive, Room 109

department: DIR

institute: NIH/NIEHS

data_processing:
Base calling and generation of FASTQ files performed using RTA and cell ranger v3.0.1
scRNA-Seq processing completed using cell ranger v3.0.1 with Gencode M17 mm10 transcriptome filtered according to 10X recommendations.
Downstream processing completed with Seurat v3.
Genome_build: mm10
Supplementary_files_format_and_content: counts

source_name: Dissociated lung cells, day 14

extract_protocol:
Lungs were harvested on day 14 post-exposure (3 mice per group) and enzymatically digested with a cocktail including collagenase Type 1, elastase, DNase1, and Dispase. After red blood cell lysis and filtering, Pdgfra=GFP+ cells were sorted using FACS (BD Aria II).
The mRNA reverse transcription and cDNA generation and amplification were carried out followed by the construction of single cell gene expression libraries according to the protocols provided by manufacturers.

treatment_protocol: Mice were dosed once with either PBS (50 ul, OP) or Bleomycin (2 U/Kg, OP)

tag: strain

value: Pdgfra-GFP JAX# 007669

value: 50 ul PBS OP

value: Pdgfra+ lung fibroblasts


title: Pdgfra-GFP Bleomycin

value: 4 U/Kg bleomycin OP


title: PB_PaLin-_08

city: Suita

first: Takashi

last: Shimbo

state: Osaka

address: 2-2 Yamadaoka

country: Japan

institute: Osaka university

data_processing:
Sequencing outputs were demultiplexed using bcl2fastq2 (https://jp.support.illumina.com/sequencing/sequencing_software/bcl2fastq-conversion-software.html)
Fastq files were aligned to Mus musculus GRCm38 reference using STAR aligner (2.7.1a; https://github.com/alexdobin/STAR)
Genome_build: GRCm38
Supplementary_files_format_and_content: Processed data files are zipped STAR output directory (Solo.out).

source_name: Mouse PB cells

extract_protocol:
Bone marrow derived Cells were filtered through 40 µM cell strainers (Falcon). Peripheral blood was collected by using 22G needle (TERUMO) with Heparin Sodium 10000 units/10mL (MOCHIDA). Red blood cells were removed using  RBC lysis buffer (BioLegend). Target cell populations were stained with antibodies and isolated by FACS AriaTMⅢ(BD Bioscience).
RNA-seq library was constructed using a modified smart-seq2 protocol. Cells were sorted into 384-well plates with barcoded oligo dT primer for each well (1 cell / well). After reverse transcription in each well, cDNA was pre-amplified using the Accel-NGS 1S Plus DNA Library Kit (Swift Biosciences, Ann Arbor, MI, USA). Purified cDNAs were tagmentationed with Amplicon Tagment enzyme (Illumina) and PCR for library construction was done by using NEBNext High-Fidelity 2× PCR Master Mix (NEB).

value: peripheral blood

value: PDGFRalpha-Cre;ROSAtdTomato


title: Femur_HSC_PaLin+_01

source_name: Mouse Femur BM cells

value: femur


title: PB_PaLin-_05


title: PB_PaLin-_06


title: Femur_HSC_PaLin+_02


title: PB_PaLin+_04


title: PB_PaLin+_02


title: PB_PaLin-_07


title: Femur_PaLin-_04


title: Femur_HSC_PaLin-_01


title: Femur_PaLin-_03


title: TfhProg rep 2


title: Femur_PaLin-_01


title: PB_PaLin+_01


title: Femur_PaLin-_02


title: Femur_PaLin+_01


title: Femur_PaLin+_02


title: Femur_PaLin+_04


title: Femur_PaLin+_03


title: OLD_1uM

first: Zhiyun

last: Wei

state: Massachusetts

address: 60 Fenwood Road

department: Neurology

data_processing:
The reads were quality controlled with FastQC, trimmed with Trimmomatic, aligned with HiSat2 to hg38, and quantified with HTSeq-count using the Galaxy platform.
Assembly: hg38
Supplementary files format and content: tab-delimited Excel files include read count for each Sample

source_name: iPSC-Neurons

extract_protocol:
Total RNA from cells was extracted using the Norgen Total RNA Purification Kit (Norgen Biotek) following the manufacturer's protocol. DNase1 was applied during RNA extraction to remove genomic DNA. RNA was eluted in nuclease-free water, and the concentration was measured using Nanodrop (Thermo Fisher Scientific).
After quality control by Agilent 2100 Bioanalyzer, the total RNA was used as input for library preparation by Novogene Co., Ltd, followed by high-throughput sequencing on Illumina HiSeq X with PE150 mode to produce approximately 20 M reads per sample.

value: iPSC-Neurons

value: Human fibroblasts were reprogrammed into iPSCs, converted into cortical-enriched NPCs, and differentiated into neuronal cells

value: 1uM oleandrin


title: OLD_5uM

value: 5uM oleandrin


title: OLD_0.1uM

value: 0.1uM oleandrin


title: PA_1uM

value: 1uM proscillaridin A


title: Femur_HSC_PaLin-_02


title: PA_0.01uM

value: 0.01uM proscillaridin A


title: PA_0.1uM

value: 0.1uM proscillaridin A


title: DGX_5uM

value: 5uM digoxin


title: DGX_1uM

value: 1uM digoxin


title: DGX_0.1uM

value: 0.1uM digoxin


title: PB_PaLin+_03


title: Veh_1

value: 0.1percent DMSO


title: Veh_3


title: Veh_2


title: RSB217-95 [Nateglinide]

data_processing:
FastQ files were trimmed of adapter sequences using Cutadapt with the following parameters: cutadapt -u 1 -a TGGAATTCTCGGGTGCCAAGG -m 15.
Trimmed reads were aligned to miRBase 21 (hg38) by using Bowtie.
Assembly: hg38
Supplementary files format and content: tab-delimited Excel files include read count for each Sample

growth_protocol: Induced pluripotent stem cell (iPSC) lines were retrieved and differentiated into neurons with NGN2 expression, as previously reported. Briefly, iPSCs were plated in mTeSR1 media at a density of 9.5x104 cells/cm2 on Matrigel (Corning #354234)-coated plates. Cells were then transduced with the following virus: pTet-O-NGN2-puro (Addgene #52047): 0.1 μL per 5x104 cells; Tet-O-FUW-eGFP (Addgene #30130): 0.05μL per 5x104 cells; Fudelta GW-rtTA (Addgene #19780): 0.11 μL per 5x104 cells. Transduced cells were dissociated with Accutase (StemCell Technologies) and plated onto Matrigel-coated plates in mTeSR1 (StemCell Technologies) at 5x104/cm2 (Day 0). On day 1, media was changed to KSR media (Knockout DMEM, 15% KOSR, 1x MEM-NEAA, 55 μM beta-mercaptoethanol, 1x GlutaMAX; Gibco) with doxycycline (2 μg/ml, Sigma-Aldrich). Doxycyline was maintained in the media for the remainder of the differentiation. On day 2, the media was changed to 1:1 KSR: N2B media with puromycin (5 μg/ml, Gibco), where N2B was composed of DMEM/F12, 1x GlutaMAX, 1x N2 supplement B (StemCell Technologies) and 0.3% dextrose (Sigma-Aldrich). Puromycin was maintained in the media throughout the differentiation. On day 3, the media was changed to N2B media + 1:100 B-27 supplement (GIBCO) and puromycin (10 μg/ml). From day 4 on, cells were cultured in NBM media (Neurobasal medium, 0.5x MEM-NEAA, 1x GlutaMAX, 0.3% dextrose) + 1:50 B-27 + BDNF, GDNF, CNTF (10 ng/ml each, Peprotech). After day 4, half of the media was replaced by fresh media twice per week. Cells were stocked on day 4 at 1~2x106 cells in 200 μL freezing media (50% day 4 media + 40% FBS + 10% DMSO) per cryovial in -80oC overnight, followed by liquid nitrogen storage. Twenty-five 96-well plates (Corning) were coated with Matrigel solution (0.2 mg/mL in DMEM/F12) at 60 μL per well for 1.5 hours at 37oC. Then, the Matrigel solution was completely removed, and 100 μL PBS (Gibco) was added per well using electronic 12-channel pipettes in speed 3 (e12c-pip; Eppendorf). The plates were temporality incubated at 37oC. Frozen day 4 iPSC-iNs were thawed in 500 μL pre-warmed resuspension media per vial, which was composed of NBM, 1:100 B27, and 1:1000 ROCKi (StemCell Technologies), and were kept in a warm metal bath to facilitate the thawing. Multiple vials were pooled into one 50 mL conical tube, then pre-warmed resuspension media were added drop-wisely to reach the volume of 40 mL. After gently mixing by reverting the tube, viable cell concentration was counted with trypan blue (Bio-Rad). The cells were spun down (220 g, 5 min, room temperature) and resuspended in day 4 media at 1x105 cells/mL. Then, PBS was completely removed from the plates, and 100 μL cell suspension was added per well, using e12c-pip at speed 3. The cells were incubated at 37oC after shaking the plates for even distribution (day 4). To reduce evaporation during incubation, plates were kept in plastic containers lined with sterile wet paper towels. On day 5, an additional 100 μL pre-warmed day 4 medium was added per well using e12c-pip in speed 1. On days 7/10/14/18, 95 μL conditioned medium was removed, and 100 μL pre-warmed day 4 medium was added per well, both using e12c-pip.

extract_protocol:
On day 20, four 10x photos were taken per well automatically using the ImageXpress Micro Confocal microscope (Molecular Devices). Then, the media in the plates was removed with approximately 20 μL media left, using a 24-channel stainless steel manifold (Drummond #3-000-101) linked with a vacuum at a low speed. With the help of Multidrop™ Combi Reagent Dispenser (Thermo Scientific) and the standard cassette (speed: low), 250 μL ice-cold DPBS (Wisent) was added per well. The DPBS was removed with approximately 20 μL liquid left, using another 24-channel stainless steel manifold linked with the vacuum at a low speed. The residual DPBS was completely removed using a mechanic 12-channel pipette. Next, 45 μL lysing solution was added per well using another Multidrop™ Combi Reagent Dispenser with the small cassette (speed: low), where the lysing solution is composed of single-cell lysis buffer (Takara #635013): 1x RNase Inhibitor Murine (NEB): nuclease-free water (Exiqon) = 19:1:190. Thorough lysis was achieved by shaking the plates on a shaker for 5 min at room temperature. The lysis samples were transferred from four 96-well plates to each 384-square-well plate using the 96-well module-coupled VPrep liquid handler (Agilent) with 30 μL tips (twice without changing tips). After sealing, the 384-square-well plates were spun down at 4000 rpm for 5 min, and 10 μL supernatant was aliquoted to a 384-well plate (Eppendorf) using the 384-well module-coupled VPrep liquid handler. The plates were finally sealed with the PlateLoc Heat Sealer (Agilent) and stored at -20oC.
To avoid RNA purification, we used RealSeq-T technology (RealSeq Biosciences) following manufacturer recommendations. In summary, cell lysates were incubated at 70C for 5 minutes on RealSeq hybridization buffer (100 mM NaCl, 50 mM Tris-HCl, 10 mM MgCl2, 1mM DTT, pH 7.9) with 1x RealSeq biotinylated DNA probes to target all miRNAs in miRbase 21. After 2 hours of incubation at 37C, 10 μL of RealSeq Beads were added, and miRNAs were captured using a 384-well Magnet Plate (Alpaqua, MA). Following three washes with RealSeq Wash buffer, miRNA was eluted from beads in 10uL of RNase-free water. All the miRNA elusion was input to prepare sequencing libraries with RealSeq-Biofluids following manufacturer instructions (RealSeq Biosciences). In summary, a single adapter and circularization approach was used. Libraries were barcoded with dual indexes and sequenced with a NextSeq 550 (Illumina, CA).

treatment_protocol: On day 19, half (three 384-well plates) of the Selleck bioactive compound library (N=1902 compounds) were pin transferred (V&P Scientific) to twelve NGN2-iN plates using the Seiko Compound Transfer Robot at 200 nL per well (final concentration at 10 μM). Positive control (Forskolin) and negative control (DMSO) were also pin transferred to the wells without library compound. The other half (three and a quarter 384-well plates) of the compound library were added to the remaining thirteen 96-well plates after one day delay (on day 20), using the identical protocol due to the time consumption.

value: Human NGN2-driven iPSC-derived neurons

value: Nateglinide


title: RSB217-96 [GW842166X]


title: RSB217-97 [Osthole]

value: Osthole


title: RSB217-93 [Mycophenolic acid]

value: Mycophenolic acid


title: RSB217-86 [Dalcetrapib (JTT-705, RO4607381)]

value: Dalcetrapib (JTT-705, RO4607381)


title: RSB217-92 [CPI-613]


title: RSB217-87 [Milrinone]

value: Milrinone


title: RSB217-91 [Moroxydine HCl]

value: Moroxydine HCl


title: RSB217-98 [URB597]


title: RSB217-88 [SB705498]


title: RSB217-84 [MK-5108 (VX-689)]


title: RSB217-85 [Manidipine 2HCl]

value: Manidipine 2HCl


title: RSB217-77 [Oleanolic Acid]

value: Oleanolic Acid


title: RSB217-80 [GW3965 HCl]

value: GW3965 HCl


title: RSB217-73 [Myricetin]

value: Myricetin


title: RSB217-76 [Tubastatin A HCl]

value: Tubastatin A HCl


title: RSB217-68 [PP121]


title: RSB217-72 [OSI-027]


title: RSB217-99 [Oxymatrine]

value: Oxymatrine


title: RSB217-70 [Omecamtiv mecarbil (CK-1827452)]

value: Omecamtiv mecarbil (CK-1827452)


title: RSB217-82 [Dinaciclib (SCH727965)]

value: Dinaciclib (SCH727965)


title: RSB217-75 [Nalidixic acid]

value: Nalidixic acid


title: RSB217-94 [PF-5274857]


title: RSB217-66 [AZD5438]


title: RSB217-65 [Luteolin]

value: Luteolin


title: RSB217-64 [3-Methyladenine]

value: Human NGN2-driven iPSC-derived neurons


title: RSB217-60 [NVP-BVU972]


title: RSB217-78 [PNU-120596]


title: RSB217-59 [Imatinib (STI571)]

value: Imatinib (STI571)


title: RSB217-69 [Methyl-Hesperidin]

value: Methyl-Hesperidin


title: RSB217-56 [CUDC-907]


title: RSB217-67 [(+)-Matrine]

value: (+)-Matrine


title: RSB217-53 [Fluocinolone Acetonide]

value: Fluocinolone Acetonide


title: RSB217-52 [Varlitinib]

value: Varlitinib


title: RSB217-55 [Gallamine Triethiodide]

value: Gallamine Triethiodide


title: RSB217-51 [Fenbendazole]

value: Fenbendazole


title: RSB217-50 [HER2-Inhibitor-1]


title: RSB217-63 [Lincomycin HCl]

value: Lincomycin HCl


title: RSB217-48 [GSK256066]


title: RSB217-44 [TAK-733]


title: RSB217-43 [Icariin]

value: Icariin


title: RSB217-49 [Famciclovir]

value: Famciclovir


title: RSB217-45 [Kaempferol]

value: Kaempferol


title: RSB217-46 [MG-132]


title: RSB217-47 [Limonin]

value: Limonin


title: RSB217-38 [Clorsulon]

value: Clorsulon


title: RSB217-62 [MK-2048]


title: RSB217-42 [Noradrenaline bitartrate monohydrate]

value: Noradrenaline bitartrate monohydrate


title: RSB217-37 [Hesperidin]

value: Hesperidin


title: RSB217-41 [Hyodeoxycholic acid (HDCA)]

value: Hyodeoxycholic acid (HDCA)


title: RSB217-351 [Buflomedil HCl]

value: Human NGN2-driven iPSC-derived neurons

value: Buflomedil HCl


title: RSB217-61 [Itraconazole]

value: Itraconazole


title: RSB217-40 [Arecoline]

value: Arecoline


title: RSB217-54 [Wortmannin]

value: Wortmannin


title: RSB217-349 [Mifepristone]

value: Mifepristone


title: RSB217-347 [Idebenone]

value: Idebenone


title: RSB217-345 [Dehydroepiandrosterone (DHEA)]

value: Dehydroepiandrosterone (DHEA)


title: RSB217-343 [Tioxolone]

value: Tioxolone


title: RSB217-336 [Milciclib (PHA-848125)]

value: Milciclib (PHA-848125)


title: RSB217-333 [Domperidone]

value: Domperidone


title: RSB217-334 [GW788388]


title: RSB217-339 [Gliclazide]

value: Gliclazide


title: RSB217-330 [Anacetrapib (MK-0859)]

value: Anacetrapib (MK-0859)


title: RSB217-331 [Clonidine HCl]

value: Clonidine HCl


title: RSB217-36 [Ribitol]

value: Ribitol


title: RSB217-35 [Hesperetin]

value: Hesperetin


title: RSB217-329 [Clindamycin HCl]

value: Clindamycin HCl


title: RSB217-33 [Glycyrrhizic Acid]

value: Human NGN2-driven iPSC-derived neurons

value: Glycyrrhizic Acid


title: RSB217-328 [AMG-458]


title: RSB217-326 [AZ 628]


title: RSB217-323 [Amantadine HCl]

value: Amantadine HCl


title: RSB217-325 [Benserazide HCl]

value: Benserazide HCl


title: RSB217-322 [PF-04691502]


title: RSB217-319 [Clindamycin palmitate HCl]

value: Clindamycin palmitate HCl


title: RSB217-313 [Miglitol]

value: Miglitol


title: RSB217-317 [Pramiracetam]

value: Pramiracetam


title: RSB217-318 [Sorafenib]

value: Sorafenib


title: RSB217-315 [Tolvaptan]

value: Tolvaptan


title: RSB217-312 [Ataluren (PTC124)]

value: Ataluren (PTC124)


title: RSB217-314 [VX-702]


title: RSB217-341 [Acemetacin]

value: Acemetacin


title: RSB217-311 [Dimethyl Fumarate]

value: Dimethyl Fumarate


title: RSB217-310 [NXY-059]


title: RSB217-309 [Clobetasol propionate]

value: Clobetasol propionate


title: RSB217-308 [Tacrolimus (FK506)]

value: Tacrolimus (FK506)


title: RSB217-306 [Fingolimod (FTY720) HCl]

value: Fingolimod (FTY720) HCl


title: RSB217-303 [Synephrine HCl]

value: Synephrine HCl


title: RSB217-307 [Thiamphenicol]

value: Thiamphenicol


title: RSB217-301 [Rotundine]

value: Human NGN2-driven iPSC-derived neurons

value: Rotundine


title: RSB217-299 [Ipriflavone (Osteofix)]

value: Ipriflavone (Osteofix)


title: RSB217-300 [TG101348 (SAR302503)]


title: RSB217-327 [Bethanechol chloride]

value: Bethanechol chloride


title: RSB217-316 [Brefeldin A]

value: Brefeldin A


title: RSB217-320 [Tubastatin A]

value: Tubastatin A


title: RSB217-298 [MK-8776 (SCH 900776)]


title: RSB217-296 [AZ 3146]


title: RSB217-297 [Aloperine]

value: Aloperine


title: RSB217-295 [20-Hydroxyecdysone]


title: RSB217-294 [Crenolanib (CP-868596)]

value: Crenolanib (CP-868596)


title: RSB217-292 [SB415286]


title: RSB217-293 [Astragaloside A]

value: Astragaloside A


title: RSB217-291 [Geniposidic acid]

value: Geniposidic acid


title: RSB217-283 [Phenylephrine HCl]

value: Phenylephrine HCl


title: RSB217-290 [AG-1478 (Tyrphostin AG-1478)]

value: AG-1478 (Tyrphostin AG-1478)


title: RSB217-286 [Pefloxacin Mesylate Dihydrate]

value: Pefloxacin Mesylate Dihydrate


title: RSB217-285 [Tetracycline HCl]

value: Tetracycline HCl


title: RSB217-287 [Xylometazoline HCl]

value: Xylometazoline HCl


title: RSB217-282 [Sitagliptin phosphate monohydrate]

value: Sitagliptin phosphate monohydrate


title: RSB217-288 [3-Aminobenzamide]


title: RSB217-304 [PHA-767491]


title: RSB217-280 [Cabozantinib malate (XL184)]

value: Cabozantinib malate (XL184)


title: RSB217-281 [Medroxyprogesterone acetate]

value: Human NGN2-driven iPSC-derived neurons

value: Medroxyprogesterone acetate


title: RSB217-279 [Isoprenaline HCl]

value: Isoprenaline HCl


title: RSB217-277 [Amoxicillin Sodium]

value: Amoxicillin Sodium


title: RSB217-276 [Diclofenac Potassium]

value: Diclofenac Potassium


title: RSB217-274 [Epinephrine HCl]

value: Epinephrine HCl


title: RSB217-271 [Paeoniflorin]

value: Paeoniflorin


title: RSB217-267 [Cephalomannine]

value: Cephalomannine


title: RSB217-266 [ZM 336372]


title: RSB217-269 [10-Deacetylbaccatin-III]


title: RSB217-264 [AMG-900]


title: RSB217-268 [JTC-801]


title: RSB217-263 [Chrysophanic Acid]

value: Chrysophanic Acid


title: RSB217-262 [TAK-901]


title: RSB217-261 [Sophocarpine]

value: Sophocarpine


title: RSB217-258 [LY411575]


title: RSB217-260 [CP-91149]


title: RSB217-256 [Bindarit]

value: Bindarit


title: RSB217-257 [Tetrandrine]

value: Tetrandrine


title: RSB217-275 [Cloxacillin Sodium]

value: Cloxacillin Sodium


title: RSB217-255 [Cortisone acetate]

value: Cortisone acetate


title: RSB217-254 [Linagliptin]

value: Linagliptin


title: RSB217-246 [Cabazitaxel]

value: Cabazitaxel


title: RSB217-238 [YO-01027]


title: RSB217-249 [Clarithromycin]

value: Clarithromycin


title: RSB217-248 [Bufexamac]

value: Human NGN2-driven iPSC-derived neurons

value: Bufexamac


title: RSB217-252 [Piceatannol]

value: Piceatannol


title: RSB217-245 [Azelastine HCl]

value: Azelastine HCl


title: RSB217-251 [Rosiglitazone]

value: Rosiglitazone


title: RSB217-239 [Sodium Danshensu]

value: Sodium Danshensu


title: RSB217-270 [PH-797804]


title: RSB217-242 [Ciclopirox ethanolamine]

value: Ciclopirox ethanolamine


title: RSB217-250 [PMSF]

value: PMSF


title: RSB217-243 [Trospium chloride]

value: Trospium chloride


title: RSB217-247 [Daphnetin]

value: Daphnetin


title: RSB217-235 [Salidroside]

value: Salidroside


title: RSB217-237 [Dihydromyricetin]

value: Dihydromyricetin


title: RSB217-233 [Rheochrysidin]

value: Rheochrysidin


title: RSB217-232 [CH5132799]


title: RSB217-229 [Sesamin]

value: Sesamin


title: RSB217-230 [A-769662]


title: RSB217-231 [Naringenin]

value: Naringenin


title: RSB217-228 [GDC-0980 (RG7422)]


title: RSB217-227 [Quercetin]

value: Quercetin


title: RSB217-225 [Polydatin]

value: Polydatin


title: RSB217-224 [Niflumic acid]

value: Human NGN2-driven iPSC-derived neurons

value: Niflumic acid


title: RSB217-223 [Tiotropium Bromide hydrate]

value: Tiotropium Bromide hydrate


title: RSB217-221 [Scopine]

value: Scopine


title: RSB217-220 [Pazopanib]

value: Pazopanib


title: RSB217-219 [Ceftiofur HCl]

value: Ceftiofur HCl


title: RSB217-218 [Zaltoprofen]

value: Zaltoprofen


title: RSB217-216 [Zanamivir]

value: Zanamivir


title: RSB217-214 [Clevudine]

value: Clevudine


title: RSB217-215 [Secnidazole]

value: Secnidazole


title: RSB217-210 [CHIR-99021 (CT99021) HCl]


title: RSB217-212 [Carbazochrome sodium sulfonate (AC-17)]

value: Carbazochrome sodium sulfonate (AC-17)


title: RSB217-208 [ADX-47273]


title: RSB217-207 [Indirubin]

value: Indirubin


title: RSB217-201 [D-Mannitol]

value: D-Mannitol


title: RSB217-196 [CAY10505]


title: RSB217-205 [Hordenine]

value: Hordenine


title: RSB217-204 [R547]


title: RSB217-200 [KW-2478]


title: RSB217-226 [TG101209]


title: RSB217-195 [Butylscopolamine Bromide]

value: Butylscopolamine Bromide


title: RSB217-206 [WAY-600]


title: RSB217-194 [AS-604850]


title: RSB217-192 [Carfilzomib (PR-171)]

value: Carfilzomib (PR-171)


title: RSB217-191 [Ritodrine HCl]

value: Ritodrine HCl


title: RSB217-190 [ARN-509]

value: Human NGN2-driven iPSC-derived neurons


title: RSB217-188 [TAE226 (NVP-TAE226)]

value: TAE226 (NVP-TAE226)


title: RSB217-186 [BYL719]


title: RSB217-185 [Ciclopirox]

value: Ciclopirox


title: RSB217-203 [Hematoxylin]

value: Hematoxylin


title: RSB217-183 [Methacycline HCl]

value: Methacycline HCl


title: RSB217-184 [INK 128 (MLN0128)]


title: RSB217-182 [GDC-0068]


title: RSB217-217 [Phenformin HCl]

value: Phenformin HCl


title: RSB217-180 [Dabrafenib (GSK2118436)]

value: Dabrafenib (GSK2118436)


title: RSB217-177 [Vardenafil HCl Trihydrate]

value: Vardenafil HCl Trihydrate


title: RSB217-175 [Aloin]

value: Aloin


title: RSB217-172 [A922500]


title: RSB217-174 [BRL-15572]


title: RSB217-187 [Dopamine HCl]

value: Dopamine HCl


title: RSB217-173 [5-hydroxytryptophan (5-HTP)]

value: 5-hydroxytryptophan (5-HTP)


title: RSB217-170 [Trametinib (GSK1120212)]

value: Trametinib (GSK1120212)


title: RSB217-167 [Tetrahydropapaverine HCl]

value: Tetrahydropapaverine HCl


title: RSB217-168 [AS-252424]


title: RSB217-171 [Yohimbine HCl]

value: Yohimbine HCl


title: RSB217-162 [PF-3845]


title: RSB217-164 [Dolutegravir (GSK1349572)]

value: Dolutegravir (GSK1349572)


title: RSB217-163 [Tanshinone IIA]

value: Tanshinone IIA


title: RSB217-165 [Taxifolin (Dihydroquercetin)]

value: Taxifolin (Dihydroquercetin)


title: RSB217-159 [Tenoxicam]

value: Human NGN2-driven iPSC-derived neurons

value: Tenoxicam


title: RSB217-161 [Tanshinone I]

value: Tanshinone I


title: RSB217-166 [A-674563]


title: RSB217-157 [Spectinomycin HCl]

value: Spectinomycin HCl


title: RSB217-154 [VU 0357121]


title: RSB217-153 [Scopolamine HBr]

value: Scopolamine HBr


title: RSB217-152 [Sofosbuvir (PSI-7977, GS-7977)]

value: Sofosbuvir (PSI-7977, GS-7977)


title: RSB217-176 [Ibrutinib (PCI-32765)]

value: Ibrutinib (PCI-32765)


title: RSB217-151 [Roxithromycin]

value: Roxithromycin


title: RSB217-150 [Torcetrapib]

value: Torcetrapib


title: RSB217-149 [Ribavirin]

value: Ribavirin


title: RSB217-148 [Sotrastaurin]

value: Sotrastaurin


title: RSB217-146 [Istradefylline]

value: Istradefylline


title: RSB217-145 [Quinine HCl Dihydrate]

value: Quinine HCl Dihydrate


title: RSB217-142 [Clinofibrate]

value: Clinofibrate


title: RSB217-144 [Ciprofibrate]

value: Ciprofibrate


title: RSB217-139 [Silibinin]

value: Silibinin


title: RSB217-140 [WAY-100635 Maleate]

value: WAY-100635 Maleate


title: RSB217-143 [Synephrine]

value: Human NGN2-driven iPSC-derived neurons

value: Synephrine


title: RSB217-133 [Salicin]

value: Salicin


title: RSB217-132 [GSK2126458 (GSK458)]


title: RSB217-134 [5-hydroxymethyl Tolterodine (PNU 200577, 5-HMT, 5-HM)]


title: RSB217-155 [Sotalol]

value: Sotalol


title: RSB217-129 [Quercetin Dihydrate]

value: Quercetin Dihydrate


title: RSB217-137 [Shikimic Acid]

value: Shikimic Acid


title: RSB217-128 [Tofacitinib (CP-690550,Tasocitinib)]

value: Tofacitinib (CP-690550,Tasocitinib)


title: RSB217-124 [A-803467]


title: RSB217-126 [Laquinimod]

value: Laquinimod


title: RSB217-127 [Propafenone HCl]

value: Propafenone HCl


title: RSB217-121 [Pancuronium dibromide]

value: Pancuronium dibromide


title: RSB217-147 [Racecadotril]

value: Racecadotril


title: RSB217-120 [AZD2014]


title: RSB217-117 [Oxymetazoline HCl]

value: Oxymetazoline HCl


title: RSB217-118 [RITA (NSC 652287)]


title: RSB217-138 [WYE-125132 (WYE-132)]


title: RSB217-136 [MK-0752]


title: RSB217-119 [Ozagrel]

value: Ozagrel


title: RSB217-222 [Aspirin]

value: Aspirin


title: RSB217-116 [I-BET151 (GSK1210151A)]


title: RSB217-115 [Olopatadine HCl]

value: Olopatadine HCl


title: RSB217-111 [Puerarin]

value: Puerarin


title: RSB217-109 [Piperine]

value: Piperine


title: RSB217-114 [M344]

value: Human NGN2-driven iPSC-derived neurons


title: RSB217-108 [A66]


title: RSB217-110 [NU7441 (KU-57788)]


title: RSB217-107 [Phlorizin]

value: Phlorizin


title: RSB217-104 [DCC-2036 (Rebastinib)]

value: DCC-2036 (Rebastinib)


title: RSB217-105 [Phloretin]

value: Phloretin


title: RSB217-123 [D-Pantothenic acid]

value: D-Pantothenic acid


title: RSB217-101 [Paeonol]

value: Paeonol


title: RSB217-9 [nc-DMSO rep6-8]

value: DMSO


title: RSB217-8 [nc-DMSO rep6-7]


title: RSB217-100 [BMS-378806]


title: RSB217-7 [nc-DMSO rep6-6]


title: RSB217-25 [nc-DMSO rep6-4]


title: RSB217-26 [nc-DMSO rep6-5]


title: RSB217-24 [nc-DMSO rep6-3]


title: RSB217-23 [nc-DMSO rep6-2]


title: RSB217-10 [nc-DMSO rep6-1]


title: RSB217-376 [pc-Forskolin rep6-4]

value: Forskolin


title: RSB211-136 [PCI-34051]


title: RSB217-359 [pc-Forskolin rep6-1]


title: RSB217-375 [pc-Forskolin rep6-3]


title: RSB217-106 [CCT128930]


title: RSB211-206 [Lornoxicam]

value: Lornoxicam


title: RSB211-302 [Ibutilide Fumarate]

value: Ibutilide Fumarate


title: RSB217-360 [pc-Forskolin rep6-2]


title: RSB211-80 [Nicorandil]

value: Nicorandil


title: RSB211-238 [Balofloxacin]

value: Balofloxacin


title: RSB211-310 [Berberine HCl]

value: Berberine HCl


title: RSB211-202 [Cyproheptadine HCl]

value: Cyproheptadine HCl


title: RSB211-285 [Ganciclovir]

value: Ganciclovir


title: RSB211-230 [Terazosin HCl]

value: Terazosin HCl


title: RSB211-294 [Gabexate Mesylate]

value: Gabexate Mesylate


title: RSB211-110 [Elvitegravir (GS-9137, JTK-303)]

value: Human NGN2-driven iPSC-derived neurons

value: Elvitegravir (GS-9137, JTK-303)


title: RSB211-350 [Formononetin]

value: Formononetin


title: RSB211-328 [Naftopidil]

value: Naftopidil


title: RSB211-216 [Ketanserin]

value: Ketanserin


title: RSB211-219 [Proparacaine HCl]

value: Proparacaine HCl


title: RSB211-218 [Volasertib (BI 6727)]

value: Volasertib (BI 6727)


title: RSB211-236 [Tiopronin]

value: Tiopronin


title: RSB211-141 [Metolazone]

value: Metolazone


title: RSB211-220 [Palomid 529 (P529)]

value: Palomid 529 (P529)


title: RSB211-286 [Azomycin]

value: Azomycin


title: RSB211-300 [Conivaptan HCl]

value: Conivaptan HCl


title: RSB211-283 [Valaciclovir HCl]

value: Valaciclovir HCl


title: RSB211-235 [Monobenzone]

value: Monobenzone


title: RSB211-334 [Atropine]

value: Atropine


title: RSB211-77 [KU-60019]


title: RSB211-200 [Memantine HCl]

value: Memantine HCl


title: RSB211-351 [Sulfamethoxazole]

value: Sulfamethoxazole


title: RSB211-222 [Tubacin]

value: Human NGN2-driven iPSC-derived neurons

value: Tubacin


title: RSB211-264 [Atorvastatin Calcium]

value: Atorvastatin Calcium


title: RSB211-44 [Isoniazid]

value: Isoniazid


title: RSB211-70 [Sulfamethizole]

value: Sulfamethizole


title: RSB211-282 [Artesunate]

value: Artesunate


title: RSB211-317 [Nicotinamide (Vitamin B3)]

value: Nicotinamide (Vitamin B3)


title: RSB211-344 [Emodin]

value: Emodin


title: RSB211-287 [Protionamide]

value: Protionamide


title: RSB211-204 [Doxifluridine]

value: Doxifluridine


title: RSB211-330 [S- (+)-Rolipram]

value: S- (+)-Rolipram


title: RSB211-345 [Fluvastatin Sodium]

value: Fluvastatin Sodium


title: RSB211-311 [Carbidopa]

value: Carbidopa


title: RSB211-105 [Tie2 kinase inhibitor]

value: Tie2 kinase inhibitor


title: RSB211-318 [Cinchonidine]

value: Cinchonidine


title: RSB211-139 [Rizatriptan Benzoate]

value: Rizatriptan Benzoate


title: RSB211-47 [KRN 633]

value: KRN 633


title: RSB211-89 [Methylprednisolone]

value: Human NGN2-driven iPSC-derived neurons

value: Methylprednisolone


title: RSB211-301 [Meprednisone]

value: Meprednisone


title: RSB211-153 [Sulfadiazine]

value: Sulfadiazine


title: RSB211-303 [Praziquantel]

value: Praziquantel


title: RSB211-46 [Levofloxacin]

value: Levofloxacin


title: RSB211-349 [Pregnenolone]

value: Pregnenolone


title: RSB211-174 [Epalrestat]

value: Epalrestat


title: RSB211-221 [Oxfendazole]

value: Oxfendazole


title: RSB211-159 [Trifluridine]

value: Trifluridine


title: RSB211-315 [Hydroxyurea]

value: Hydroxyurea


title: RSB211-134 [Sulindac]

value: Sulindac


title: RSB211-217 [Erdosteine]

value: Erdosteine


title: RSB211-270 [Rivastigmine Tartrate]

value: Rivastigmine Tartrate


title: RSB211-175 [Triamcinolone Acetonide]

value: Triamcinolone Acetonide


title: RSB217-189 [Asaraldehyde]

value: Asaraldehyde


title: RSB211-255 [Curcumin]

value: Curcumin


title: RSB211-123 [Nicotinic Acid]

value: Human NGN2-driven iPSC-derived neurons

value: Nicotinic Acid


title: RSB211-313 [Dipyridamole]

value: Dipyridamole


title: RSB211-348 [Fisetin]

value: Fisetin


title: RSB211-143 [Silodosin]

value: Silodosin


title: RSB211-207 [Ursodiol]

value: Ursodiol


title: RSB211-158 [DAPT (GSI-IX)]

value: DAPT (GSI-IX)


title: RSB217-181 [L-Adrenaline]

value: L-Adrenaline


title: RSB211-314 [Caffeic Acid]

value: Caffeic Acid


title: RSB211-155 [Oxytetracycline (Terramycin)]

value: Oxytetracycline (Terramycin)


title: RSB211-254 [Aloe-emodin]

value: Aloe-emodin


title: RSB211-86 [Givinostat (ITF2357)]

value: Givinostat (ITF2357)


title: RSB211-250 [3-Indolebutyric acid (IBA)]

value: 3-Indolebutyric acid (IBA)


title: RSB211-64 [Tebipenem Pivoxil]

value: Tebipenem Pivoxil


title: RSB211-278 [Arbutin]

value: Arbutin


title: RSB211-223 [Carvedilol]

value: Carvedilol


title: RSB211-74 [Rimantadine]

value: Rimantadine


title: RSB211-71 [Pomalidomide]

value: Human NGN2-driven iPSC-derived neurons

value: Pomalidomide


title: RSB211-211 [Aciclovir]

value: Aciclovir


title: RSB211-95 [Methocarbamol]

value: Methocarbamol


title: RSB211-43 [AZD8055]


title: RSB211-38 [Alibendol]

value: Alibendol


title: RSB211-213 [Amiloride HCl]

value: Amiloride HCl


title: RSB211-57 [Adefovir Dipivoxil]

value: Adefovir Dipivoxil


title: RSB211-152 [PIK-293]


title: RSB211-290 [Ambrisentan]

value: Ambrisentan


title: RSB217-179 [Maprotiline HCl]

value: Maprotiline HCl


title: RSB211-189 [Ranolazine]

value: Ranolazine


title: RSB211-72 [Sulphadimethoxine]

value: Sulphadimethoxine


title: RSB211-157 [Ethionamide]

value: Ethionamide


title: RSB211-296 [Cisatracurium Besylate]

value: Cisatracurium Besylate


title: RSB211-151 [Cefditoren Pivoxil]

value: Cefditoren Pivoxil


title: RSB211-163 [Darunavir Ethanolate]

value: Darunavir Ethanolate


title: RSB211-210 [Eltrombopag]

value: Eltrombopag


title: RSB211-312 [Bilobalide]

value: Bilobalide


title: RSB211-269 [?6-??-?Aminocaproic acid]

value: Human NGN2-driven iPSC-derived neurons

value: ?6-??-?Aminocaproic acid


title: RSB211-127 [Rifapentine]

value: Rifapentine


title: RSB211-42 [Nystatin (Fungicidin)]

value: Nystatin (Fungicidin)


title: RSB211-90 [AG-14361]


title: RSB211-60 [LY2886721]


title: RSB211-187 [Fenofibrate]

value: Fenofibrate


title: RSB211-150 [OSI-420]


title: RSB211-106 [Propylthiouracil]

value: Propylthiouracil


title: RSB211-307 [Sparfloxacin]

value: Sparfloxacin


title: RSB211-342 [Diosmin]

value: Diosmin


title: RSB211-343 [Flutamide]

value: Flutamide


title: RSB211-147 [Rifampin]

value: Rifampin


title: RSB211-85 [Indapamide]

value: Indapamide


title: RSB211-94 [MLN2238]


title: RSB211-308 [Bergenin]

value: Bergenin


title: RSB211-203 [Amprenavir]

value: Amprenavir


title: RSB211-277 [Diethylstilbestrol]

value: Diethylstilbestrol


title: RSB211-93 [Mesna]

value: Mesna


title: RSB211-154 [Formestane]

value: Formestane


title: RSB211-198 [Cyproterone Acetate]

value: Cyproterone Acetate


title: RSB211-125 [Enoxacin]

value: Human NGN2-driven iPSC-derived neurons

value: Enoxacin


title: RSB211-319 [Vitamin B12]

value: Vitamin B12


title: RSB211-327 [Emtricitabine]

value: Emtricitabine


title: RSB211-167 [Acetylcysteine]

value: Acetylcysteine


title: RSB211-194 [Phentolamine Mesylate]

value: Phentolamine Mesylate


title: RSB211-88 [Dichlorphenamide]

value: Dichlorphenamide


title: RSB211-55 [Glipizide]

value: Glipizide


title: RSB211-340 [Dihydroartemisinin (DHA)]

value: Dihydroartemisinin (DHA)


title: RSB211-191 [Acadesine]

value: Acadesine


title: RSB211-246 [CX-4945 (Silmitasertib)]

value: CX-4945 (Silmitasertib)


title: RSB211-229 [Ketorolac]

value: Ketorolac


title: RSB211-82 [RAF265 (CHIR-265)]


title: RSB211-341 [Metronidazole]

value: Metronidazole


title: RSB211-188 [TAME]

value: TAME


title: RSB211-293 [Chloramphenicol]

value: Chloramphenicol


title: RSB211-322 [Arbidol HCl]

value: Arbidol HCl


title: RSB211-138 [BMS-265246]


title: RSB211-248 [(+)-Usniacin]

value: (+)-Usniacin


title: RSB211-228 [Tolnaftate]

value: Human NGN2-driven iPSC-derived neurons

value: Tolnaftate


title: RSB211-201 [Amphotericin B]

value: Amphotericin B


title: RSB211-339 [Avobenzone]

value: Avobenzone


title: RSB211-54 [LDE225 (NVP-LDE225,Erismodegib)]

value: LDE225 (NVP-LDE225,Erismodegib)


title: RSB211-324 [Licofelone]

value: Licofelone


title: RSB211-40 [Irsogladine]

value: Irsogladine


title: RSB211-196 [Nimesulide]

value: Nimesulide


title: RSB211-59 [Zalcitabine]

value: Zalcitabine


title: RSB211-242 [AR-42]


title: RSB211-171 [Naproxen]

value: Naproxen


title: RSB211-66 [Methoxsalen]

value: Methoxsalen


title: RSB211-265 [Trichlormethiazide]

value: Trichlormethiazide


title: RSB211-233 [Telbivudine]

value: Telbivudine


title: RSB211-249 [Lomustine]

value: Lomustine


title: RSB211-185 [Ramipril]

value: Ramipril


title: RSB211-306 [Baicalin]

value: Baicalin


title: RSB211-61 [Azathioprine]

value: Azathioprine


title: RSB211-56 [Dabigatran Etexilate]

value: Human NGN2-driven iPSC-derived neurons

value: Dabigatran Etexilate


title: RSB211-162 [Ginkgolide A]

value: Ginkgolide A


title: RSB211-145 [Pyrazinamide]

value: Pyrazinamide


title: RSB211-274 [Andrographolide]

value: Andrographolide


title: RSB211-115 [Telmisartan]

value: Telmisartan


title: RSB211-199 [Erythromycin]

value: Erythromycin


title: RSB211-205 [Chlorothiazide]

value: Chlorothiazide


title: RSB211-212 [LY2157299]


title: RSB211-178 [PP242]


title: RSB211-262 [Mecarbinate]

value: Mecarbinate


title: RSB211-166 [Uridine]

value: Uridine


title: RSB211-263 [Flucytosine]

value: Flucytosine


title: RSB211-100 [Methscopolamine]

value: Methscopolamine


title: RSB211-276 [Apigenin]

value: Apigenin


title: RSB211-299 [Sulfanilamide]

value: Sulfanilamide


title: RSB211-52 [GSK1292263]


title: RSB211-50 [AZD8330]


title: RSB211-305 [Idoxuridine]

value: Idoxuridine


title: RSB211-271 [Aminoglutethimide]

value: Aminoglutethimide


title: RSB211-53 [Gemcitabine]

value: Gemcitabine


title: RSB211-181 [Rifaximin]

value: Human NGN2-driven iPSC-derived neurons

value: Rifaximin


title: RSB211-338 [Cytisine]

value: Cytisine


title: RSB211-260 [Ozagrel HCl]

value: Ozagrel HCl


title: RSB211-75 [Tazarotene]

value: Tazarotene


title: RSB211-335 [Estradiol]

value: Estradiol


title: RSB211-227 [Ketoprofen]

value: Ketoprofen


title: RSB211-275 [Pefloxacin Mesylate]

value: Pefloxacin Mesylate


title: RSB211-148 [NVP-BHG712]


title: RSB211-34 [Sulfisoxazole]

value: Sulfisoxazole


title: RSB211-190 [CAL-101 (Idelalisib, GS-1101)]

value: CAL-101 (Idelalisib, GS-1101)


title: RSB211-37 [Dapagliflozin]

value: Dapagliflozin


title: RSB211-131 [Reserpine]

value: Reserpine


title: RSB211-273 [Daidzein]

value: Daidzein


title: RSB211-239 [Ezetimibe]

value: Ezetimibe


title: RSB211-209 [Acipimox]

value: Acipimox


title: RSB211-258 [Moxonidine]

value: Moxonidine


title: RSB211-295 [Flurbiprofen]

value: Flurbiprofen


title: RSB211-124 [GSK461364]

value: Human NGN2-driven iPSC-derived neurons


title: RSB211-118 [SB505124]


title: RSB211-244 [BKM120 (NVP-BKM120, Buparlisib)]

value: BKM120 (NVP-BKM120, Buparlisib)


title: RSB211-108 [Fluticasone propionate]

value: Fluticasone propionate


title: RSB211-113 [Prednisolone]

value: Prednisolone


title: RSB211-111 [Apixaban]

value: Apixaban


title: RSB211-132 [Pyrimethamine]

value: Pyrimethamine


title: RSB211-119 [Rifabutin]

value: Rifabutin


title: RSB211-297 [Disulfiram]

value: Disulfiram


title: RSB211-51 [Piroxicam]

value: Piroxicam


title: RSB211-116 [AST-1306]


title: RSB211-261 [Estrone]

value: Estrone


title: RSB211-109 [TWS119]


title: RSB211-133 [Furosemide]

value: Furosemide


title: RSB211-245 [Albendazole Oxide]

value: Albendazole Oxide


title: RSB211-266 [Famotidine]

value: Famotidine


title: RSB211-186 [UK 383367]


title: RSB211-165 [Prednisone]

value: Prednisone


title: RSB211-99 [BIRB 796 (Doramapimod)]

value: BIRB 796 (Doramapimod)


title: RSB211-333 [Hydrochlorothiazide]

value: Hydrochlorothiazide


title: RSB211-323 [Desonide]

value: Desonide


title: RSB211-257 [Dofetilide]

value: Human NGN2-driven iPSC-derived neurons

value: Dofetilide


title: RSB211-103 [Sulfasalazine]

value: Sulfasalazine


title: RSB211-135 [Cefdinir]

value: Cefdinir


title: RSB211-83 [Gemfibrozil]

value: Gemfibrozil


title: RSB211-97 [Fasudil (HA-1077) HCl]

value: Fasudil (HA-1077) HCl


title: RSB211-146 [BMS-794833]


title: RSB211-329 [Progesterone]

value: Progesterone


title: RSB211-121 [Nevirapine]

value: Nevirapine


title: RSB211-96 [MLN9708]


title: RSB211-243 [Azithromycin]

value: Azithromycin


title: RSB211-129 [Semagacestat (LY450139)]

value: Semagacestat (LY450139)


title: RSB211-226 [Gimeracil]

value: Gimeracil


title: RSB211-231 [Adenosine]

value: Adenosine


title: RSB211-49 [Deferasirox]

value: Deferasirox


title: RSB211-279 [Diphenhydramine HCl]

value: Diphenhydramine HCl


title: RSB211-195 [Allopurinol Sodium]

value: Allopurinol Sodium


title: RSB211-149 [Beta Carotene]

value: Beta Carotene


title: RSB211-35 [Febuxostat]

value: Febuxostat


title: RSB211-289 [Aminophylline]

value: Human NGN2-driven iPSC-derived neurons

value: Aminophylline


title: RSB211-104 [Mometasone furoate]

value: Mometasone furoate


title: RSB211-259 [Isradipine]

value: Isradipine


title: RSB211-41 [Pimobendan]

value: Pimobendan


title: RSB211-101 [RO4929097]


title: RSB211-214 [Telatinib]

value: Telatinib


title: RSB211-173 [Nitazoxanide]

value: Nitazoxanide


title: RSB211-180 [CYT387]


title: RSB211-161 [Sulfameter]

value: Sulfameter


title: RSB211-225 [Nitrofural]

value: Nitrofural


title: RSB211-352 [Ferulic Acid]

value: Ferulic Acid


title: RSB211-172 [Rebamipide]

value: Rebamipide


title: RSB211-98 [Meglumine]

value: Meglumine


title: RSB211-122 [AZD8931 (Sapitinib)]

value: AZD8931 (Sapitinib)


title: RSB211-160 [Mubritinib (TAK 165)]

value: Mubritinib (TAK 165)


title: RSB211-193 [Orlistat]

value: Orlistat


title: RSB211-336 [Roflumilast]

value: Roflumilast


title: RSB211-197 [Zafirlukast]

value: Zafirlukast


title: RSB211-65 [AT7867]

value: Human NGN2-driven iPSC-derived neurons


title: RSB211-176 [Aspartame]

value: Aspartame


title: RSB211-33 [SB408124]


title: RSB211-337 [Diclofenac Sodium]

value: Diclofenac Sodium


title: RSB211-325 [Didanosine]

value: Didanosine


title: RSB211-7 [nc-DMSO rep5-7]

value: DMSO


title: RSB211-321 [Busulfan]

value: Busulfan


title: RSB211-144 [Ketotifen Fumarate]

value: Ketotifen Fumarate


title: RSB211-288 [Baicalein]

value: Baicalein


title: RSB211-26 [nc-DMSO rep5-4]


title: RSB211-10 [nc-DMSO rep5-3]


title: RSB211-375 [pc-Forskolin rep5-3]

value: Forskolin


title: RSB211-69 [VX-809 (Lumacaftor)]

value: VX-809 (Lumacaftor)


title: RSB211-23 [nc-DMSO rep5-2]


title: RSB211-376 [pc-Forskolin rep5-2]


title: RSB211-84 [AZD1480]


title: RSB211-24 [nc-DMSO rep5-1]


title: RSB211-359 [pc-Forskolin rep5-1]


title: RSB211-67 [BMS-777607]


title: RSB211-192 [PIK-294]


title: RSB211-304 [Probucol]

value: Probucol


title: RSB196-287 [Raltitrexed]

value: Raltitrexed


title: RSB211-272 [Betaxolol]

value: Betaxolol


title: RSB196-213 [Cisplatin]

value: Cisplatin


title: RSB211-320 [Cryptotanshinone]

value: Cryptotanshinone


title: RSB211-8 [nc-DMSO rep5-8]


title: RSB211-177 [Vidarabine]

value: Vidarabine


title: RSB211-9 [nc-DMSO rep5-6]


title: RSB196-87 [Cabozantinib (XL184, BMS-907351)]

value: Cabozantinib (XL184, BMS-907351)


title: RSB196-181 [Capecitabine]

value: Human NGN2-driven iPSC-derived neurons

value: Capecitabine


title: RSB196-323 [MLN8054]


title: RSB211-360 [pc-Forskolin rep5-4]


title: RSB211-25 [nc-DMSO rep5-5]


title: RSB196-327 [U0126-EtOH]


title: RSB196-228 [Megestrol Acetate]

value: Megestrol Acetate


title: RSB196-326 [Meropenem]

value: Meropenem


title: RSB196-70 [Fludarabine Phosphate]

value: Fludarabine Phosphate


title: RSB196-143 [Tandutinib (MLN518)]

value: Tandutinib (MLN518)


title: RSB196-232 [Ki16425]


title: RSB196-50 [Pirarubicin]

value: Pirarubicin


title: RSB196-139 [STF-62247]


title: RSB196-341 [Bisoprolol fumarate]

value: Bisoprolol fumarate


title: RSB196-293 [KU-55933 (ATM Kinase Inhibitor)]

value: KU-55933 (ATM Kinase Inhibitor)


title: RSB196-101 [Lapatinib (GW-572016) Ditosylate]

value: Lapatinib (GW-572016) Ditosylate


title: RSB196-67 [BMS-536924]


title: RSB196-317 [Dimesna]

value: Dimesna


title: RSB196-207 [SB431542]


title: RSB196-89 [Everolimus (RAD001)]

value: Everolimus (RAD001)


title: RSB196-160 [SP600125]


title: RSB196-322 [Isotretinoin]

value: Isotretinoin


title: RSB196-210 [SB525334]


title: RSB196-307 [CUDC-101]


title: RSB196-283 [Bicalutamide]

value: Bicalutamide


title: RSB196-215 [CP-724714]


title: RSB196-84 [Linezolid]

value: Linezolid


title: RSB196-262 [Glimepiride]

value: Glimepiride


title: RSB196-247 [BIIB021]


title: RSB196-85 [XL147]


title: RSB196-334 [Ondansetron HCl]

value: Ondansetron HCl


title: RSB196-159 [Roscovitine (Seliciclib,CYC202)]

value: Human NGN2-driven iPSC-derived neurons

value: Roscovitine (Seliciclib,CYC202)


title: RSB196-325 [Vatalanib (PTK787) 2HCl]

value: Vatalanib (PTK787) 2HCl


title: RSB196-297 [PF-04217903]


title: RSB196-51 [BI 2536]


title: RSB196-245 [MK-2866 (GTx-024)]


title: RSB196-196 [Camptothecin]

value: Camptothecin


title: RSB196-311 [Finasteride]

value: Finasteride


title: RSB196-127 [17-AAG (Tanespimycin)]

value: 17-AAG (Tanespimycin)


title: RSB196-347 [Fluorouracil (5-Fluoracil, 5-FU)]

value: Fluorouracil (5-Fluoracil, 5-FU)


title: RSB196-36 [Clofarabine]

value: Clofarabine


title: RSB196-135 [Rapamycin (Sirolimus)]

value: Rapamycin (Sirolimus)


title: RSB196-279 [BIBR 1532]

value: BIBR 1532


title: RSB196-191 [AT13387]


title: RSB196-79 [Erlotinib HCl (OSI-744)]

value: Erlotinib HCl (OSI-744)


title: RSB196-285 [Fulvestrant]

value: Fulvestrant


title: RSB196-284 [Cyclosporine]

value: Cyclosporine


title: RSB196-45 [FG-4592]


title: RSB196-252 [Pralatrexate]

value: Pralatrexate


title: RSB196-239 [SB202190 (FHPI)]


title: RSB196-303 [BTZ043 Racemate]

value: BTZ043 Racemate


title: RSB196-217 [Valproic acid sodium salt (Sodium valproate)]


title: RSB196-119 [AT9283]


title: RSB196-108 [Enzalutamide (MDV3100)]

value: Enzalutamide (MDV3100)


title: RSB196-153 [Barasertib (AZD1152-HQPA)]

value: Barasertib (AZD1152-HQPA)


title: RSB196-147 [AG-490 (Tyrphostin B42)]

value: Human NGN2-driven iPSC-derived neurons

value: AG-490 (Tyrphostin B42)


title: RSB196-174 [Biperiden HCl]

value: Biperiden HCl


title: RSB196-69 [Bortezomib (PS-341)]

value: Bortezomib (PS-341)


title: RSB196-111 [NVP-AEW541]


title: RSB196-343 [Tivozanib (AV-951)]

value: Tivozanib (AV-951)


title: RSB196-148 [PHA-680632]


title: RSB196-198 [Carmofur]

value: Carmofur


title: RSB196-189 [PA-824]


title: RSB196-281 [Anastrozole]

value: Anastrozole


title: RSB196-151 [SNS-032 (BMS-387032)]


title: RSB196-38 [YM201636]


title: RSB196-158 [Thiazovivin]

value: Thiazovivin


title: RSB196-288 [Natamycin]

value: Natamycin


title: RSB196-59 [GSK690693]


title: RSB196-37 [Linifanib (ABT-869)]

value: Linifanib (ABT-869)


title: RSB196-179 [S3I-201]


title: RSB196-315 [Decitabine]

value: Decitabine


title: RSB196-264 [TG100-115]


title: RSB196-251 [Regorafenib (BAY 73-4506)]

value: Regorafenib (BAY 73-4506)


title: RSB196-76 [AG-1024]


title: RSB196-125 [Andarine]

value: Andarine


title: RSB196-260 [Genistein]

value: Genistein


title: RSB196-63 [Odanacatib (MK-0822)]

value: Odanacatib (MK-0822)


title: RSB196-309 [Exemestane]

value: Exemestane


title: RSB196-331 [GDC-0879]


title: RSB196-295 [GSK1904529A]


title: RSB196-163 [Trichostatin A (TSA)]

value: Trichostatin A (TSA)


title: RSB196-40 [OSI-930]

value: Human NGN2-driven iPSC-derived neurons


title: RSB196-268 [Loratadine]

value: Loratadine


title: RSB196-75 [Dasatinib]

value: Dasatinib


title: RSB196-131 [PD0325901]


title: RSB196-338 [BIX 02189]


title: RSB196-332 [Naftopidil DiHCl]

value: Naftopidil DiHCl


title: RSB196-114 [Sildenafil Citrate]

value: Sildenafil Citrate


title: RSB196-267 [Iniparib (BSI-201)]

value: Iniparib (BSI-201)


title: RSB196-344 [CP-673451]


title: RSB196-220 [MC1568]


title: RSB196-82 [Bimatoprost]

value: Bimatoprost


title: RSB196-110 [Dienogest]

value: Dienogest


title: RSB196-290 [Ki8751]


title: RSB196-299 [LAQ824 (Dacinostat)]

value: LAQ824 (Dacinostat)


title: RSB196-206 [Floxuridine]

value: Floxuridine


title: RSB196-278 [Aztreonam]

value: Aztreonam


title: RSB196-214 [Zosuquidar (LY335979) 3HCl]

value: Zosuquidar (LY335979) 3HCl


title: RSB196-165 [Vandetanib (ZD6474)]

value: Vandetanib (ZD6474)


title: RSB196-107 [Motesanib Diphosphate (AMG-706)]

value: Motesanib Diphosphate (AMG-706)


title: RSB196-243 [WZ4002]


title: RSB196-292 [Epothilone B (EPO906, Patupilone)]

value: Epothilone B (EPO906, Patupilone)


title: RSB196-123 [ADL5859 HCl]

value: ADL5859 HCl


title: RSB196-138 [Avagacestat (BMS-708163)]

value: Avagacestat (BMS-708163)


title: RSB196-77 [Ridaforolimus (Deforolimus, MK-8669)]

value: Human NGN2-driven iPSC-derived neurons

value: Ridaforolimus (Deforolimus, MK-8669)


title: RSB196-130 [Posaconazole]

value: Posaconazole


title: RSB196-48 [Etoposide]

value: Etoposide


title: RSB196-78 [Temozolomide]

value: Temozolomide


title: RSB196-54 [Rocuronium Bromide]

value: Rocuronium Bromide


title: RSB196-142 [WYE-354]


title: RSB196-44 [Dexrazoxane HCl (ICRF-187, ADR-529)]

value: Dexrazoxane HCl (ICRF-187, ADR-529)


title: RSB196-112 [Nepafenac]

value: Nepafenac


title: RSB196-96 [Rolipram]

value: Rolipram


title: RSB196-313 [Cladribine]

value: Cladribine


title: RSB196-155 [Paclitaxel]

value: Paclitaxel


title: RSB196-99 [Imatinib Mesylate (STI571)]

value: Imatinib Mesylate (STI571)


title: RSB196-72 [Topotecan HCl]

value: Topotecan HCl


title: RSB196-329 [ZM 447439]


title: RSB196-61 [JNJ-38877605]


title: RSB196-104 [Vinblastine]

value: Vinblastine


title: RSB196-141 [Sunitinib Malate]

value: Sunitinib Malate


title: RSB196-204 [Epothilone A]

value: Epothilone A


title: RSB196-46 [Oxaliplatin]

value: Oxaliplatin


title: RSB196-235 [SB216763]

value: Human NGN2-driven iPSC-derived neurons


title: RSB196-187 [Ganetespib (STA-9090)]

value: Ganetespib (STA-9090)


title: RSB196-167 [Vorinostat (SAHA, MK0683)]

value: Vorinostat (SAHA, MK0683)


title: RSB196-137 [Sorafenib Tosylate]

value: Sorafenib Tosylate


title: RSB196-265 [Belinostat (PXD101)]

value: Belinostat (PXD101)


title: RSB196-202 [Cilostazol]

value: Cilostazol


title: RSB196-173 [Elesclomol (STA-4783)]

value: Elesclomol (STA-4783)


title: RSB196-185 [MK-8245]


title: RSB196-226 [Ifosfamide]

value: Ifosfamide


title: RSB196-154 [Atazanavir Sulfate]

value: Atazanavir Sulfate


title: RSB196-176 [Budesonide]

value: Budesonide


title: RSB196-94 [Repaglinide]

value: Repaglinide


title: RSB196-164 [BX-912]


title: RSB196-120 [Voriconazole]

value: Voriconazole


title: RSB196-86 [Alfuzosin HCl]

value: Alfuzosin HCl


title: RSB196-246 [PIK-93]


title: RSB196-203 [GDC-0941]


title: RSB196-249 [PD98059]


title: RSB196-216 [Daclatasvir (BMS-790052)]

value: Daclatasvir (BMS-790052)


title: RSB196-300 [Gestodene]

value: Gestodene


title: RSB196-218 [Iloperidone]

value: Iloperidone


title: RSB196-168 [Altretamine]

value: Altretamine


title: RSB196-92 [Ranolazine 2HCl]

value: Human NGN2-driven iPSC-derived neurons

value: Ranolazine 2HCl


title: RSB196-47 [Selumetinib (AZD6244)]

value: Selumetinib (AZD6244)


title: RSB196-312 [MK-1775]


title: RSB196-106 [JNJ-7706621]


title: RSB196-83 [Triciribine]

value: Triciribine


title: RSB196-212 [Oligomycin A]

value: Oligomycin A


title: RSB196-150 [Cilomilast]

value: Cilomilast


title: RSB196-178 [AZD6482]


title: RSB196-116 [Tizanidine HCl]

value: Tizanidine HCl


title: RSB196-88 [Clopidogrel]

value: Clopidogrel


title: RSB196-199 [Olaparib (AZD2281, Ku-0059436)]


title: RSB196-233 [ZSTK474]


title: RSB196-118 [Tranilast]

value: Tranilast


title: RSB196-266 [Lansoprazole]

value: Lansoprazole


title: RSB196-183 [CEP-18770 (Delanzomib)]

value: CEP-18770 (Delanzomib)


title: RSB196-162 [Acarbose]

value: Acarbose


title: RSB196-224 [AEE788 (NVP-AEE788)]

value: AEE788 (NVP-AEE788)


title: RSB196-222 [HMN-214]


title: RSB196-80 [Vincristine]

value: Vincristine


title: RSB196-282 [Tadalafil]

value: Tadalafil


title: RSB196-330 [Nafamostat Mesylate]

value: Nafamostat Mesylate


title: RSB196-52 [Resveratrol]

value: Resveratrol


title: RSB196-62 [Trilostane]

value: Human NGN2-driven iPSC-derived neurons

value: Trilostane


title: RSB196-255 [XAV-939]


title: RSB196-109 [Nilotinib (AMN-107)]

value: Nilotinib (AMN-107)


title: RSB196-208 [FT-207 (NSC 148958)]


title: RSB196-238 [Etomidate]

value: Etomidate


title: RSB196-91 [Mocetinostat (MGCD0103)]

value: Mocetinostat (MGCD0103)


title: RSB196-237 [SB203580]


title: RSB196-156 [VX-745]


title: RSB196-144 [Vemurafenib (PLX4032, RG7204)]

value: Vemurafenib (PLX4032, RG7204)


title: RSB196-103 [Lenalidomide (CC-5013)]

value: Lenalidomide (CC-5013)


title: RSB196-140 [PD173074]


title: RSB196-261 [Vismodegib (GDC-0449)]

value: Vismodegib (GDC-0449)


title: RSB196-242 [PHA-793887]


title: RSB196-42 [Dacarbazine]

value: Dacarbazine


title: RSB196-171 [Y-27632 2HCl]


title: RSB196-349 [Methotrexate]

value: Methotrexate


title: RSB196-93 [BMS-754807]


title: RSB196-254 [Betamethasone]

value: Betamethasone


title: RSB196-60 [Tigecycline]

value: Tigecycline


title: RSB196-244 [Naratriptan]

value: Naratriptan


title: RSB196-302 [Drospirenone]

value: Drospirenone


title: RSB196-333 [LY294002]


title: RSB196-182 [Calcitriol]

value: Calcitriol


title: RSB196-190 [GSK429286A]


title: RSB196-350 [Saxagliptin]

value: Saxagliptin


title: RSB196-348 [Telaprevir (VX-950)]

value: Telaprevir (VX-950)


title: RSB196-186 [TSU-68 (SU6668, Orantinib)]

value: Human NGN2-driven iPSC-derived neurons

value: TSU-68 (SU6668, Orantinib)


title: RSB196-339 [PIK-75]


title: RSB196-192 [Pimasertib (AS-703026)]

value: Pimasertib (AS-703026)


title: RSB196-310 [AT7519]


title: RSB196-346 [DMXAA (Vadimezan)]

value: DMXAA (Vadimezan)


title: RSB196-316 [LY2811376]


title: RSB196-280 [Alprostadil]

value: Alprostadil


title: RSB196-336 [Pelitinib (EKB-569)]

value: Pelitinib (EKB-569)


title: RSB196-194 [Bumetanide]

value: Bumetanide


title: RSB196-240 [Fluconazole]

value: Fluconazole


title: RSB196-304 [Ruxolitinib (INCB018424)]

value: Ruxolitinib (INCB018424)


title: RSB196-320 [BIX 02188]


title: RSB196-166 [Adapalene]

value: Adapalene


title: RSB196-270 [GSK1059615]


title: RSB196-296 [Amonafide]

value: Amonafide


title: RSB196-256 [Mycophenolate Mofetil]

value: Mycophenolate Mofetil


title: RSB196-200 [Cetirizine DiHCl]

value: Cetirizine DiHCl


title: RSB196-351 [Bendamustine HCl]

value: Bendamustine HCl


title: RSB196-258 [Fluvoxamine maleate]

value: Fluvoxamine maleate


title: RSB196-43 [Saracatinib (AZD0530)]

value: Saracatinib (AZD0530)


title: RSB196-314 [Quizartinib (AC220)]

value: Quizartinib (AC220)


title: RSB196-340 [AZD7762]

value: Human NGN2-driven iPSC-derived neurons


title: RSB196-291 [OSI-906 (Linsitinib)]

value: OSI-906 (Linsitinib)


title: RSB196-263 [Brivanib (BMS-540215)]

value: Brivanib (BMS-540215)


title: RSB196-277 [Ritonavir]

value: Ritonavir


title: RSB196-324 [Lopinavir]

value: Lopinavir


title: RSB196-90 [Droxinostat]

value: Droxinostat


title: RSB196-274 [Cephalexin]

value: Cephalexin


title: RSB196-219 [TGX-221]


title: RSB196-352 [EX 527 (Selisistat)]

value: EX 527 (Selisistat)


title: RSB196-41 [Axitinib]

value: Axitinib


title: RSB196-9 [nc-DMSO rep4-7]

value: DMSO


title: RSB196-25 [nc-DMSO rep4-8]


title: RSB196-230 [Streptozotocin (STZ)]

value: Streptozotocin (STZ)


title: RSB196-298 [Acitretin]

value: Acitretin


title: RSB196-294 [BMS-707035]


title: RSB196-10 [nc-DMSO rep4-4]


title: RSB196-272 [MGCD-265 analog]

value: MGCD-265 analog


title: RSB196-23 [nc-DMSO rep4-3]


title: RSB196-24 [nc-DMSO rep4-1]


title: RSB196-7 [nc-DMSO rep4-6]


title: RSB196-8 [nc-DMSO rep4-2]


title: RSB196-26 [nc-DMSO rep4-5]


title: RSB196-375 [pc-Forskolin rep4-2]

value: Forskolin


title: RSB196-359 [pc-Forskolin rep4-3]


title: RSB196-376 [pc-Forskolin rep4-1]


title: RSB181-208 [PTC-209 HBr]

value: PTC-209 HBr


title: RSB181-298 [CEP-32496]


title: RSB196-360 [pc-Forskolin rep4-4]


title: RSB181-80 [BTB06584]


title: RSB181-330 [GSK3787]


title: RSB181-159 [GSK2606414]


title: RSB181-272 [BIX 01294]


title: RSB181-109 [TIC10]


title: RSB181-176 [Voreloxin (SNS-595)]

value: Voreloxin (SNS-595)


title: RSB196-211 [ABT-751 (E7010)]


title: RSB181-240 [Filgotinib (GLPG0634)]

value: Filgotinib (GLPG0634)


title: RSB181-234 [N6022]

value: Human NGN2-driven iPSC-derived neurons


title: RSB181-93 [SC75741]


title: RSB181-58 [Necrostatin-1]


title: RSB181-112 [MPI-0479605]


title: RSB181-42 [Sal003]


title: RSB181-172 [Y-320]


title: RSB181-204 [ML323]


title: RSB181-334 [WY-14643 (Pirinixic Acid)]

value: WY-14643 (Pirinixic Acid)


title: RSB181-47 [PD123319]


title: RSB181-44 [ME0328]


title: RSB181-169 [AZD1080]


title: RSB181-239 [PF-04620110]


title: RSB181-302 [AZD5363]


title: RSB181-125 [TAK-632]


title: RSB181-301 [RepSox]

value: RepSox


title: RSB181-89 [SRPIN340]


title: RSB181-237 [I-BET-762]


title: RSB181-170 [VGX-1027]


title: RSB181-155 [Rilpivirine]

value: Rilpivirine


title: RSB181-235 [AGI-5198]


title: RSB181-157 [CPI-203]


title: RSB181-171 [DMH1]


title: RSB181-74 [FPH2 (BRD-9424)]


title: RSB181-60 [UPF 1069]


title: RSB181-64 [GDC-0349]


title: RSB181-199 [Batimastat (BB-94)]

value: Batimastat (BB-94)


title: RSB181-266 [PQ 401]


title: RSB181-223 [AZ191]


title: RSB181-111 [EPZ-6438]


title: RSB181-48 [ZLN005]


title: RSB181-144 [HO-3867]


title: RSB181-270 [SMI-4a]


title: RSB181-317 [Loxistatin Acid (E-64C)]

value: Loxistatin Acid (E-64C)


title: RSB181-347 [KN-93 Phosphate]

value: KN-93 Phosphate


title: RSB181-332 [Tariquidar]

value: Tariquidar


title: RSB181-91 [4?8C]


title: RSB181-59 [CNX-774]


title: RSB181-219 [CW069]


title: RSB181-142 [HJC0350]


title: RSB181-77 [NLG919]


title: RSB181-331 [Erastin]

value: Erastin


title: RSB181-137 [IU1]


title: RSB181-174 [AZD7545]


title: RSB181-128 [PluriSIn #1 (NSC 14613)]

value: PluriSIn #1 (NSC 14613)


title: RSB181-107 [KPT-185]


title: RSB181-285 [PTC-209]


title: RSB181-78 [VER-50589]


title: RSB181-185 [TG003]


title: RSB181-300 [TAK-438]


title: RSB181-191 [Tasisulam]

value: Tasisulam


title: RSB181-79 [Zebularine]

value: Zebularine


title: RSB181-167 [LGK-974]


title: RSB181-45 [HSP990 (NVP-HSP990)]

value: HSP990 (NVP-HSP990)


title: RSB181-153 [IWP-L6]


title: RSB181-151 [PJ34 HCl]

value: PJ34 HCl


title: RSB181-329 [AGI-6780]


title: RSB181-73 [LGX818]


title: RSB181-61 [SKLB1002]


title: RSB181-349 [PD 151746]


title: RSB181-217 [K-Ras(G12C) inhibitor 6]

value: K-Ras(G12C) inhibitor 6


title: RSB181-46 [LEE011]


title: RSB181-57 [SGC-CBP30]


title: RSB181-255 [OTX015]


title: RSB181-87 [PD173955]


title: RSB181-76 [VER-49009]


title: RSB181-106 [Nexturastat A]

value: Nexturastat A


title: RSB181-119 [CO-1686 (AVL-301)]


title: RSB181-232 [INCB024360]


title: RSB181-336 [NSC 23766]


title: RSB181-283 [4E1RCat]


title: RSB181-168 [Trelagliptin]

value: Trelagliptin


title: RSB181-196 [GS-9973]

value: Human NGN2-driven iPSC-derived neurons


title: RSB181-43 [KY02111]


title: RSB181-141 [CGK 733]

value: CGK 733


title: RSB181-263 [BIO]

value: BIO


title: RSB181-251 [PF-562271 HCl]


title: RSB181-104 [Triapine]

value: Triapine


title: RSB181-41 [PF-3758309]


title: RSB181-75 [(+)-JQ1]


title: RSB181-187 [TMP269]


title: RSB181-205 [Mdivi-1]


title: RSB181-189 [UNC2881]


title: RSB181-203 [LY2835219]


title: RSB181-319 [Aloxistatin]

value: Aloxistatin


title: RSB181-295 [Losmapimod (GW856553X)]

value: Losmapimod (GW856553X)


title: RSB181-90 [ABT-199 (GDC-0199)]


title: RSB181-72 [FPH1 (BRD-6125)]


title: RSB181-127 [RG2833 (RGFP109)]


title: RSB181-70 [FH1(BRD-K4477)]


title: RSB181-230 [IM-12]


title: RSB181-264 [GSK2636771]


title: RSB181-86 [BMS-345541]


title: RSB181-108 [EHT 1864]


title: RSB181-115 [Edoxaban]

value: Edoxaban


title: RSB181-136 [INH6]


title: RSB181-313 [(-)-p-Bromotetramisole Oxalate]

value: (-)-p-Bromotetramisole Oxalate


title: RSB181-215 [K-Ras(G12C) inhibitor 9]

value: K-Ras(G12C) inhibitor 9


title: RSB181-287 [UNC669]


title: RSB181-139 [LDN-57444]


title: RSB181-88 [Dynasore]

value: Dynasore


title: RSB181-124 [NSC 405020]


title: RSB181-201 [Ilomastat (GM6001, Galardin)]

value: Ilomastat (GM6001, Galardin)


title: RSB181-297 [OAC1]


title: RSB181-56 [Butein]

value: Butein


title: RSB181-121 [NMS-873]


title: RSB181-126 [Optovin]

value: Optovin


title: RSB181-94 [Macitentan]

value: Macitentan


title: RSB181-134 [INH1]


title: RSB181-299 [Alvelestat (AZD9668)]

value: Alvelestat (AZD9668)


title: RSB181-311 [Phosphoramidon Disodium Salt]

value: Phosphoramidon Disodium Salt


title: RSB181-103 [XL888]


title: RSB181-328 [Tyrphostin AG 1296]

value: Tyrphostin AG 1296


title: RSB181-213 [6H05]

value: Human NGN2-driven iPSC-derived neurons


title: RSB181-296 [GW9508]


title: RSB181-294 [PRX-08066 Maleic acid]

value: PRX-08066 Maleic acid


title: RSB181-135 [P22077]


title: RSB181-55 [NMS-P937 (NMS1286937)]


title: RSB181-100 [PI-1840]


title: RSB181-85 [Golgicide A]

value: Golgicide A


title: RSB181-227 [ONX-0914 (PR-957)]


title: RSB181-198 [XMD8-92]


title: RSB181-163 [TCID]

value: TCID


title: RSB181-53 [AZD2858]


title: RSB181-166 [ML167]


title: RSB181-292 [AG-18]


title: RSB181-195 [C646]


title: RSB181-96 [Lomeguatrib]

value: Lomeguatrib


title: RSB181-345 [KN-62]


title: RSB181-315 [Z-FA-FMK]

value: Z-FA-FMK


title: RSB181-281 [4EGI-1]


title: RSB181-236 [Santacruzamate A (CAY10683)]

value: Santacruzamate A (CAY10683)


title: RSB181-327 [OG-L002]


title: RSB181-279 [GNE-9605]


title: RSB181-277 [GNE-0877]


title: RSB181-62 [PU-H71]


title: RSB181-262 [Rocilinostat (ACY-1215)]

value: Rocilinostat (ACY-1215)


title: RSB181-179 [STF-118804]


title: RSB181-83 [MM-102]


title: RSB181-325 [IOX1]


title: RSB181-343 [CGP 57380]


title: RSB181-326 [TCS 359]

value: TCS 359


title: RSB181-291 [Thiamet G]

value: Thiamet G


title: RSB181-228 [WH-4-023]


title: RSB181-120 [Sabutoclax]

value: Sabutoclax


title: RSB181-260 [Tenovin-1]


title: RSB181-323 [Bromosporine]

value: Bromosporine


title: RSB181-26 [nc-DMSO rep3-8]

value: DMSO


title: RSB181-101 [3-Deazaneplanocin A (DZNeP)]

value: 3-Deazaneplanocin A (DZNeP)


title: RSB181-307 [E-64]


title: RSB181-51 [KPT-330]


title: RSB181-147 [RVX-208]


title: RSB181-25 [nc-DMSO rep3-5]


title: RSB181-7 [nc-DMSO rep3-3]


title: RSB181-35 [Zotarolimus(ABT-578)]


title: RSB181-68 [CRT0044876]


title: RSB181-359 [pc-Forskolin rep3-4]

value: Forskolin


title: RSB181-23 [nc-DMSO rep3-2]


title: RSB181-84 [Scriptaid]

value: Scriptaid


title: RSB181-10 [nc-DMSO rep3-6]


title: RSB181-24 [nc-DMSO rep3-1]


title: RSB181-8 [nc-DMSO rep3-4]


title: RSB181-9 [nc-DMSO rep3-7]


title: RSB181-360 [pc-Forskolin rep3-3]


title: RSB181-376 [pc-Forskolin rep3-2]


title: RSB181-375 [pc-Forskolin rep3-1]


title: RSB163-353 [XL019]


title: RSB163-354 [Wnt-C59 (C59)]


title: RSB163-70 [Vitamin D3]

value: Vitamin D3


title: RSB163-224 [Vitamin D2]

value: Human NGN2-driven iPSC-derived neurons

value: Vitamin D2


title: RSB163-155 [Vilazodone HCl]

value: Vilazodone HCl


title: RSB163-263 [Troxipide]

value: Troxipide


title: RSB163-29 [Tylosin tartrate]

value: Tylosin tartrate


title: RSB163-62 [Valganciclovir HCl]

value: Valganciclovir HCl


title: RSB163-345 [VS-5584 (SB2343)]


title: RSB163-119 [Uracil]

value: Uracil


title: RSB163-118 [Trometamol]

value: Trometamol


title: RSB163-83 [Triamterene]

value: Triamterene


title: RSB163-255 [Triclabendazole]

value: Triclabendazole


title: RSB163-215 [Tolcapone]

value: Tolcapone


title: RSB163-186 [TTNPB (Arotinoid Acid)]

value: TTNPB (Arotinoid Acid)


title: RSB163-139 [Tolperisone HCl]

value: Tolperisone HCl


title: RSB163-199 [Triptolide (PG490)]

value: Triptolide (PG490)


title: RSB163-11 [Trimethoprim]

value: Trimethoprim


title: RSB163-73 [Tinidazole]

value: Tinidazole


title: RSB163-47 [Triflusal]

value: Triflusal


title: RSB163-260 [Timolol Maleate]

value: Human NGN2-driven iPSC-derived neurons

value: Timolol Maleate


title: RSB163-44 [Ticarcillin sodium]

value: Ticarcillin sodium


title: RSB163-259 [Tilmicosin]

value: Tilmicosin


title: RSB163-231 [Tetrahydrozoline HCl]

value: Tetrahydrozoline HCl


title: RSB181-324 [Empagliflozin (BI 10773)]

value: Empagliflozin (BI 10773)


title: RSB163-14 [Sulfamethazine]

value: Sulfamethazine


title: RSB163-324 [Sulfamethoxypyridazine]

value: Sulfamethoxypyridazine


title: RSB181-341 [Puromycin 2HCl]

value: Puromycin 2HCl


title: RSB163-13 [Sulfamerazine]

value: Sulfamerazine


title: RSB163-20 [Tripelennamine HCl]

value: Tripelennamine HCl


title: RSB163-117 [Sulfaguanidine]

value: Sulfaguanidine


title: RSB163-84 [Sulfacetamide Sodium]

value: Sulfacetamide Sodium


title: RSB163-261 [Tolazoline HCl]

value: Tolazoline HCl


title: RSB163-85 [Spiramycin]

value: Spiramycin


title: RSB163-262 [Sodium Phenylbutyrate]

value: Sodium Phenylbutyrate


title: RSB163-15 [Sodium salicylate]

value: Sodium salicylate


title: RSB163-214 [Sodium Picosulfate]

value: Human NGN2-driven iPSC-derived neurons

value: Sodium Picosulfate


title: RSB163-78 [Sodium Nitrite]

value: Sodium Nitrite


title: RSB163-68 [Sodium Nitroprusside]

value: Sodium Nitroprusside


title: RSB163-77 [Sodium 4-Aminosalicylate]

value: Sodium 4-Aminosalicylate


title: RSB163-79 [Propranolol HCl]

value: Propranolol HCl


title: RSB163-319 [Sodium ascorbate]

value: Sodium ascorbate


title: RSB163-197 [Schisandrin B (Sch B)]

value: Schisandrin B (Sch B)


title: RSB163-216 [Probenecid]

value: Probenecid


title: RSB163-181 [Procainamide HCl]

value: Procainamide HCl


title: RSB163-69 [Ronidazole]

value: Ronidazole


title: RSB163-217 [Procaine HCl]

value: Procaine HCl


title: RSB163-321 [Prucalopride Succinat]

value: Prucalopride Succinat


title: RSB163-189 [QNZ (EVP4593)]

value: QNZ (EVP4593)


title: RSB163-180 [Promethazine HCl]

value: Promethazine HCl


title: RSB163-318 [Serotonin HCl]

value: Serotonin HCl


title: RSB163-93 [Pramoxine HCl]

value: Pramoxine HCl


title: RSB163-313 [Primaquine Diphosphate]

value: Human NGN2-driven iPSC-derived neurons

value: Primaquine Diphosphate


title: RSB163-57 [Pheniramine Maleate]

value: Pheniramine Maleate


title: RSB163-125 [Tiratricol]

value: Tiratricol


title: RSB163-191 [SC-514]


title: RSB163-271 [Pentoxyverine Citrate]

value: Pentoxyverine Citrate


title: RSB163-204 [Pentamidine]

value: Pentamidine


title: RSB163-229 [Olsalazine Sodium]

value: Olsalazine Sodium


title: RSB163-165 [Oxiracetam]

value: Oxiracetam


title: RSB163-307 [Oxybuprocaine HCl]

value: Oxybuprocaine HCl


title: RSB163-284 [pc-Forskolin rep2-4]

value: Forskolin


title: RSB163-359 [Oprozomib (ONX 0912)]

value: Oprozomib (ONX 0912)


title: RSB163-380 [pc-Forskolin rep2-2]


title: RSB163-332 [pc-Forskolin rep2-1]


title: RSB163-148 [nc-DMSO rep2-3]

value: DMSO


title: RSB163-100 [nc-DMSO rep2-4]


title: RSB163-53 [nc-DMSO rep2-5]


title: RSB163-172 [Nelfinavir Mesylate]

value: Nelfinavir Mesylate


title: RSB163-228 [Norethindrone]

value: Norethindrone


title: RSB163-337 [MNS (3,4-Methylenedioxy-?-nitrostyrene, MDBN)]


title: RSB163-365 [MK-8745]


title: RSB163-63 [Nabumetone]

value: Nabumetone


title: RSB163-52 [nc-DMSO rep2-2]


title: RSB163-4 [nc-DMSO rep2-1]


title: RSB163-5 [nc-DMSO rep2-6]


title: RSB163-205 [Mirabegron]

value: Mirabegron


title: RSB163-355 [PD168393]


title: RSB163-121 [Mezlocillin Sodium]

value: Mezlocillin Sodium


title: RSB163-236 [pc-Forskolin rep2-3]

value: Human NGN2-driven iPSC-derived neurons


title: RSB163-308 [Oxaprozin]

value: Oxaprozin


title: RSB163-211 [Ouabain]

value: Ouabain


title: RSB163-16 [Methylthiouracil]

value: Methylthiouracil


title: RSB163-67 [Methyclothiazide]

value: Methyclothiazide


title: RSB163-123 [Nifuroxazide]

value: Nifuroxazide


title: RSB163-293 [Montelukast Sodium]

value: Montelukast Sodium


title: RSB163-230 [Nafcillin Sodium]

value: Nafcillin Sodium


title: RSB163-227 [Methazolamide]

value: Methazolamide


title: RSB163-80 [Mequinol]

value: Mequinol


title: RSB163-194 [Meptazinol HCl]

value: Meptazinol HCl


title: RSB163-182 [Meclofenamate Sodium]

value: Meclofenamate Sodium


title: RSB163-374 [IWR-1-endo]


title: RSB163-373 [IWP-2]


title: RSB163-178 [Labetalol HCl]

value: Labetalol HCl


title: RSB163-26 [Mepivacaine HCl]

value: Mepivacaine HCl


title: RSB163-154 [Luliconazole]

value: Luliconazole


title: RSB163-81 [Mefenamic Acid]

value: Mefenamic Acid


title: RSB163-209 [Hyoscyamine]

value: Hyoscyamine


title: RSB163-190 [JZL184]

value: Human NGN2-driven iPSC-derived neurons


title: RSB163-220 [Hydroxyzine 2HCl]

value: Hydroxyzine 2HCl


title: RSB163-92 [Ifenprodil Tartrate]

value: Ifenprodil Tartrate


title: RSB163-188 [JNK-IN-8]


title: RSB163-257 [Histamine 2HCl]

value: Histamine 2HCl


title: RSB163-218 [Homatropine Methylbromide]

value: Homatropine Methylbromide


title: RSB163-72 [Guanabenz Acetate]

value: Guanabenz Acetate


title: RSB163-241 [Halcinonide]

value: Halcinonide


title: RSB163-90 [Halobetasol Propionate]

value: Halobetasol Propionate


title: RSB163-219 [Homatropine Bromide]

value: Homatropine Bromide


title: RSB163-375 [GSK2334470]


title: RSB163-366 [GSK J4 HCl]

value: GSK J4 HCl


title: RSB163-87 [Levobetaxolol HCl]

value: Levobetaxolol HCl


title: RSB163-86 [Lomerizine HCl]

value: Lomerizine HCl


title: RSB163-141 [Furaltadone HCl]

value: Furaltadone HCl


title: RSB163-24 [Gliquidone]

value: Gliquidone


title: RSB163-264 [Levodropropizine]

value: Levodropropizine


title: RSB163-75 [Griseofulvin]

value: Griseofulvin


title: RSB163-306 [Fluorometholone Acetate]

value: Fluorometholone Acetate


title: RSB163-201 [Lithocholic acid]

value: Human NGN2-driven iPSC-derived neurons

value: Lithocholic acid


title: RSB163-142 [Isosorbide]

value: Isosorbide


title: RSB163-38 [Flumequine]

value: Flumequine


title: RSB163-163 [Flufenamic acid]

value: Flufenamic acid


title: RSB163-323 [Flopropione]

value: Flopropione


title: RSB163-305 [Fidaxomicin]

value: Fidaxomicin


title: RSB163-195 [Fexofenadine HCl]

value: Fexofenadine HCl


title: RSB163-91 [Fenspiride HCl]

value: Fenspiride HCl


title: RSB163-157 [EUK 134]

value: EUK 134


title: RSB163-159 [Etofibrate]

value: Etofibrate


title: RSB163-202 [Ethambutol HCl]

value: Ethambutol HCl


title: RSB163-277 [Ethamsylate]

value: Ethamsylate


title: RSB163-167 [Etizolam]

value: Etizolam


title: RSB163-27 [Ethynodiol diacetate]

value: Ethynodiol diacetate


title: RSB163-251 [Estradiol Benzoate]

value: Estradiol Benzoate


title: RSB163-21 [Entacapone]

value: Entacapone


title: RSB163-303 [Erythritol]

value: Human NGN2-driven iPSC-derived neurons

value: Erythritol


title: RSB163-327 [Epinastine HCl]

value: Epinastine HCl


title: RSB163-364 [EPZ5676]


title: RSB163-158 [Efaproxiral Sodium]

value: Efaproxiral Sodium


title: RSB163-268 [Dropropizine]

value: Dropropizine


title: RSB163-95 [Droperidol]

value: Droperidol


title: RSB163-71 [Escitalopram Oxalate]

value: Escitalopram Oxalate


title: RSB163-177 [Digoxin]

value: Digoxin


title: RSB163-225 [Doxapram HCl]

value: Doxapram HCl


title: RSB163-270 [Dinitolmide]

value: Dinitolmide


title: RSB163-203 [Doxycycline HCl]

value: Doxycycline HCl


title: RSB163-184 [Dicoumarol]

value: Dicoumarol


title: RSB163-226 [Dibucaine HCl]

value: Dibucaine HCl


title: RSB163-316 [Doxylamine Succinate]

value: Doxylamine Succinate


title: RSB163-221 [Flavoxate HCl]

value: Flavoxate HCl


title: RSB163-242 [Dexlansoprazole]

value: Dexlansoprazole


title: RSB163-162 [Diacerein]

value: Diacerein


title: RSB163-254 [Desvenlafaxine]

value: Human NGN2-driven iPSC-derived neurons

value: Desvenlafaxine


title: RSB163-208 [Desloratadine]

value: Desloratadine


title: RSB163-253 [Desvenlafaxine Succinate]

value: Desvenlafaxine Succinate


title: scRNAseq_IgG_day28_rep1

city: Nagasaki

first: Katsuyuki

last: Yui

state: Nagasaki

address: 長崎市坂本１丁目12番4号

institute: Nagasaki University

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
scRNAseq_IgG_day28_barcodes.tsv.gz
scRNAseq_IgG_day28_features.tsv.gz
scRNAseq_IgG_day28_matrix.mtx.gz

data_processing:
Data was analyzed using Seurat v4.2.0. Cells with greater than 3% mitochondrial RNA were excluded. Cells with < 1,500, <1,500, <1,000 and <1,000, or > 5,000, >5,000, >4,000 and >3,000 detected genes were also excluded for each dataset (IgG-treated Day 7, and anti-IL-27-treated Days 7, 14, and 28), respectively.
Assembly: mm10-2020-A
Supplementary files format and content: 10x Genomics output files: barcodes.tsv.gz, features.tsv.gz, matrix.mtx.gz

source_name: spleen

extract_protocol:
CD4+ T cells were prepared from spleen using mouse CD4+ T cell Isolation Kit (Miltenyi Biotech) and AutoMACS cell separator (Miltenyi Biotech) according to manufacturer’s instructions. Enriched CD4+ T cells, which included PbT-II cells, were incubated with a panel of TotalSeqTM -C antibodies (BioLegend) and surface antibody markers in PBS + 1% BSA: TotalSeq™-C0238 Rat IgG2a for isotype control (clone RTK2758), TotalSeq™-C0078 anti-CD49d (clone R1-2), TotalSeq™-C0198 anti-CD127 (clone A7R34), and TotalSeq™-C0250 anti-KLRG1, as well as anti-CD4 (clone GK1.5), anti- TCR β chain (clone H57-597), anti-TCR anti-CD45.1 (clone A20), and 7AAD. Stained CD4+ T cells were washed using the recommended Cell Wash Protocol 1 in preparation for 10X Single Cell RNA sequencing (Chromium Next GEM Single Cell 5' v2 protocol). PbT-II cells (CD4+CD45.1+TCR+) were sorted using FACSAria II cell sorter (BD Biosciences). FACS-sorted cells were collected in PBS + 1%BSA after washing, and resulted in >99% purity and >98% viability in all samples.
Single-cell RNA-seq libraries were prepared using the Chromium Next GEM Single Cell 5’ Reagent Kits v2 (Dual Index; 10X Genomics) according to the manufacturer’s instructions. Libraries were quantified using Bioanalyzer High Sensitivity Chip (Agilent). Gene expression libraries and cell surface protein libraries were pooled for library construction and sequencing was performed using MGISeq-2000RS.

value: spleen

value: CD4+ T cells

value: IgG

tag: library type

value: gene expression library

tag: antibodies/tags

value: Anti-IgG2a/TotalSeq-C0238 ; Anti-CD127/TotalSeq-C0198 ; Anti KLRG1/TotalSeq-C0250 ; Anti CD49d/TotalSeq-C0078


title: scRNAseq_anti-IL-27_day14_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
scRNAseq_sample3
scRNAseq_anti-IL-27_day14_barcodes.tsv.gz
scRNAseq_anti-IL-27_day14_features.tsv.gz
scRNAseq_anti-IL-27_day14_matrix.mtx.gz

data_processing:
Data was analyzed using Seurat v4.2.0. Cells with greater than 3% mitochondrial RNA were excluded. Cells with < 1,500, <1,500, <1,000 and <1,000, or > 5,000, >5,000, >4,000 and >3,000 detected genes were also excluded for each dataset (IgG-treated Day 7, and anti-IL-27-treated Days 7, 14, and 28), respectively.
Assembly: mm10-2020-A
Supplementary files format and content: 10x Genomics output files: barcodes.tsv.gz, features.tsv.gz, matrix.mtx.gz
Library strategy: CITE-seq (Cellular Indexing of Transcriptomes and Epitopes by sequencing)

value: anti-IL-27 mAb

tag: infection

value: Pcc

tag: time


title: RSB163-19 [Darifenacin HBr]

value: Darifenacin HBr


title: RSB163-94 [Difluprednate]

value: Difluprednate


title: RSB163-265 [Deoxyarbutin]

value: Deoxyarbutin


title: RSB163-269 [Cyclizine 2HCl]

value: Cyclizine 2HCl


title: scRNAseq_IgG_day07_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
scRNAseq_sample1
scRNAseq_IgG_day07_barcodes.tsv.gz
scRNAseq_IgG_day07_features.tsv.gz
scRNAseq_IgG_day07_matrix.mtx.gz


title: RSB163-111 [Cyromazine]

value: Cyromazine


title: RSB163-266 [Clorprenaline HCl]

value: Clorprenaline HCl


title: RSB163-210 [Cyclamic  acid]

value: Human NGN2-driven iPSC-derived neurons

value: Cyclamic  acid


title: scRNAseq_anti-IL-27_day07_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
scRNAseq_sample2
scRNAseq_anti-IL-27_day07_barcodes.tsv.gz
scRNAseq_anti-IL-27_day07_features.tsv.gz
scRNAseq_anti-IL-27_day07_matrix.mtx.gz


title: RSB163-289 [Clofibric Acid]

value: Clofibric Acid


title: CITEseq (Antibody Capture)_IgG_day07_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
CITEseq_sample1
scRNAseq_IgG_day07_barcodes.tsv.gz
scRNAseq_IgG_day07_features.tsv.gz
scRNAseq_IgG_day07_matrix.mtx.gz

molecule: protein

value: cell surface protein library


title: CITEseq (Antibody Capture)_anti-IL-27_day14_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
CITEseq_sample3
scRNAseq_anti-IL-27_day14_barcodes.tsv.gz
scRNAseq_anti-IL-27_day14_features.tsv.gz
scRNAseq_anti-IL-27_day14_matrix.mtx.gz

value: spleen

value: Anti-IgG2a/TotalSeq-C0238 ; Anti-CD127/TotalSeq-C0198 ; Anti KLRG1/TotalSeq-C0250 ; Anti CD49d/TotalSeq-C0080


title: RSB163-130 [Cinchophen]

value: Cinchophen


title: scRNAseq_anti-IL-27_day28_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
scRNAseq_sample4
scRNAseq_anti-IL-27_day28_barcodes.tsv.gz
scRNAseq_anti-IL-27_day28_features.tsv.gz
scRNAseq_anti-IL-27_day28_matrix.mtx.gz

value: CD4+ T cells

value: gene expression library


title: RSB163-249 [Clofazimine]

value: Clofazimine


title: CITEseq (Antibody Capture)_anti-IL-27_day28_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
CITEseq_sample4
scRNAseq_anti-IL-27_day28_barcodes.tsv.gz
scRNAseq_anti-IL-27_day28_features.tsv.gz
scRNAseq_anti-IL-27_day28_matrix.mtx.gz

value: anti-IL-27 mAb

value: Pcc

value: Anti-IgG2a/TotalSeq-C0238 ; Anti-CD127/TotalSeq-C0198 ; Anti KLRG1/TotalSeq-C0250 ; Anti CD49d/TotalSeq-C0081


title: CITEseq (Antibody Capture)_anti-IL-27_day07_rep1

address: 長崎市坂本１丁目12番4号

description:
10x Genomics - Chromium Single Cell 5' v2 workflow with Feature Barcode technology
CITEseq_sample2
scRNAseq_anti-IL-27_day07_barcodes.tsv.gz
scRNAseq_anti-IL-27_day07_features.tsv.gz
scRNAseq_anti-IL-27_day07_matrix.mtx.gz

value: Anti-IgG2a/TotalSeq-C0238 ; Anti-CD127/TotalSeq-C0198 ; Anti KLRG1/TotalSeq-C0250 ; Anti CD49d/TotalSeq-C0079