title: High Calorie, Day 5, 25C, JRK mutant, Rep 2, ZT14


title: High Calorie, Day 5, 25C, JRK mutant, Rep 2, ZT10

status: Public on Dec 05 2023

type: SRA

city: Evanston

first: William

last: Kath

state: IL

address: 2145 Sheridan Rd

department: Engineering Sciences and Applied Mathematics

country: USA

institute: Northwestern University

library_source: transcriptomic

data_processing:
Single-end reads were quality-assessed with FastQC and then trimmed with Atropos version 1.1.31 using the options atropos -a AGATCGGAAGAGCACACGTCTGAACTCCAGTCAC --minimum-length 16
Reads were then aligned and quantified using STAR (version 2.7.10a_alpha_220818) using the options  --outFilterType BySJout --alignIntronMax 1000000  --quantMode GeneCounts TranscriptomeSAM
RSEM (version 1.3.1) was then used with options --strandedness none to produce tags-per-million (TPM) counts for each gene from transcriptome alignments.
Assembly: Ensembl Drosophila melanogaster BDGP6.32 reference (release 107)
Supplementary files format and content: tab-delimited text file includes TPM values for each sample

molecule: total RNA

organism: Drosophila melanogaster

source_name: fat body (FB)

growth_protocol: All the flies used for experiments were first raised on a standard yeast-cornmeal-molasses based diet under a light-dark (LD) 12:12h cycle. Young mated female (~3 days old) flies (w^{1118}: Bloomington stock number 5905, Clk-Jrk: backcrossed 7 times to w^{1118}) of ~24 hours cohorts were entrained at either 25C or 18C for 5 days in 12L:12D cycles on a standard or diluted diet (Control: 15% [w/v] Sucrose and Yeast, 15SY; Dietary Restriction: 5% [w/v] Sucrose and Yeast, 5SY).

extract_protocol:
To collect dissected fat body samples at 2-hour and 4-hour intervals from ZT0 (set to 8AM) to ZT22 set (set to 10PM) during the daytime only, flies were entrained in two separate incubators with inverse light:dark schedule (LD and DL). On the day of sampling, flies were directly dissected without dry ice to harvest fat tissues in the abdomen. Pinned flies were cut to remove organs in the abdomen (intestine, ovaries, malpighian tubules, etc). Fat tissues attached to epidermis was collected. Dissected fat body tissues from 10 flies were homogenized in pH 7.4 PBS for 2 min using a Kontes motor and pestle, and were incubated TRIzol LS Reagent (Thermo Fisher, Waltham, MA) for 15 min. RNA was extracted according to the manufacturer's instructions and residual DNA in the homogenized samples was removed by RNAse free DNase I (Thermo Fisher Scientific). Quality of RNA samples were checked with Agilent 2100 Bioanalyzer.
cDNA library was constructed with poly(A) selected mRNA using Truseq RNA library preparation kit and then sequenced at the Genomics Core Facility at the University of Chicago on Illumina HiSeq 2000 System.

tag: tissue

value: fat body (FB)


title: High Calorie, Day 5, 25C, JRK mutant, Rep 2, ZT06


title: High Calorie, Day 5, 25C, JRK mutant, Rep 2, ZT02


title: High Calorie, Day 5, 25C, JRK mutant, Rep 1, ZT22


title: High Calorie, Day 5, 25C, JRK mutant, Rep 1, ZT18


title: Low Calorie, Day 5, 25C, WT, Rep 2, ZT06


title: High Calorie, Day 5, 25C, JRK mutant, Rep 1, ZT14


title: High Calorie, Day 5, 25C, JRK mutant, Rep 1, ZT06


title: High Calorie, Day 5, 25C, JRK mutant, Rep 1, ZT10


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT22


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT20


title: High Calorie, Day 5, 25C, JRK mutant, Rep 1, ZT02


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT18


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT12


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT06


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT10


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT08


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT14


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT02


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT04


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT24


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT22


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT18


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT20


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT14


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT16


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT12


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT24


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT02


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT04


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT24


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT08


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT06


title: High Calorie, Day 5, 25C, WT, Rep 2, ZT16


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT18


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT22


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT16


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT10


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT14


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT12


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT08


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT22


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT06


title: High Calorie, Day 5, 25C, WT, Rep 1, ZT10


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT24


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT02


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT12


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT18


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT16


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT20


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT04


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT14


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT08


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT06


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT04


title: High Calorie, Day 5, 18C, WT, Rep 2, ZT20


title: High Calorie, Day 5,18C, WT, Rep 1, ZT02


title: COHAG

city: Stockholm

first: Cheng

last: Zhao

state: Stockholm

address: H9 Klinisk vetenskap,171 77 Stockholm

department: Clinical Science

country: Sweden

institute: Karolinska institute

description: 10x Genomics

library_source: transcriptomic single cell

data_processing:
Reads mapping and gene expression quantification:Sequencing data were aligned and quantified by using the Cell Ranger Pipeline v7.0.0 (10x Genomics) with default settings against the Rattus norvegicus reference genome (v.6.0, release 104, downloaded from the Ensemblwebsite)
Quality control and normalization: Low-quality cells were removed based on the number of expressed genes (nGene) and the expression level of mitochondrial genes (percent.mito). Specifically, cells with percent.mito less than 0.15 and 750 < nGene < 6000 were retained. Doublet discrimination was implemented using the doubletFinder_v3 function in the DoubletFinder package (v.2.0.3) for each sample individually. Following the selection of high-quality cells, we further filtered based on genes. Genes that excluded mitochondrial genes were considered truly expressed if they contained one or more counts in at least five cells (assessed for each sample separately). Log-normalized counts were calculated using the deconvolution strategy implemented by the computeSumFactors function in the scran package (v.1.14.6). Rescaled normalization was performed using the multiBatchNorm function in the batchelor package (v.1.2.4) to ensure that the size factors were comparable across samples. The log-normalized expression after rescaling was used in marker gene detection and differential gene expression analysis.
Data integration, dimensionality reduction and clustering: We integrated the filtered count matrices from 3 samples using the sctransform approach implemented in the Seurat package (v.4.2.0) on the 3000 anchor features. After integration, principal component analysis (PCA) was performed on the integrated data followed by embedding into low-dimensional space with Uniform Manifold Approximation and Projection (UMAP) based on the top 40 dimensions. Clusters were generated by graph-based method using the FindClusters function from the Seurat package and assigned to cell types by consulting the expression of known marker genes and automatic annotation from the SingleR package (v.1.4.1). Proliferating cells were identified by the high-level expression of Top2a, and Stmn1 and excluded from further analysis. To identify detailed types of fibroblast cells, cells from the 2 fibroblast clusters were further extracted and integrated based on 2000 anchor features and top 30 dimensions. Sub-fibroblast clusters were further identified using the FindClusters function based on fibroblast-only PCA dimensions and by requiring at least one highly expressed marker (power > 0.4 using ‘roc’ test)  (Figure 7 and Figure S5). Raw counts for cells belonging to the same fibroblast subclusters were aggregated into a pseudo-bulk sample. Normalization of expression for pseudo-bulk samples was calculated using the estimateSizeFactors function, followed by the estimateDispersions function from the R package DESeq(v.1.38.0). The log-transformed and normalized gene expression values of expressed genes were used to calculate the Spearman correlation among different subclusters, followed by hierarchical clustering by the hclust function in R.
Assembly: rn6
Supplementary files format and content: results from cellranger

molecule: polyA RNA

organism: Rattus norvegicus

source_name: skin tissue

growth_protocol: SD male rats at 6-8 weeks were housed on a 12-h light/dark cycle with free access to water and standard diet (15% fat by energy).

extract_protocol:
Rat skin specimens（7 days of hydrogel treated wound）were cleaned with PBS and digested using the Epidermis Dissociation Kit (Miltenyi biotec, 130-095-928) for ~1 hours at 37℃ to obtain cell suspension. Then the filler was used to purify the above cell suspension, and ACK buffer (Lonza, 10-548E) was used to remove red blood cell. The resulting cells were necessary to reach >90% of cell viabilities and resuspended in PBS containning 0.04 wt% Bovine Serum Albumin (BSA).
Single-cell RNA-seq libraries were made with the single cell 3 'Library and Gel Bead Kit V3.1(10x Genomics, 1000121)  and sequenced using an Illumina NovaSeq6000 (150bp x2, 25～40k reads/cell). It is estimated that approximately 8000 cells will be recovered per sample.

treatment_protocol: SD male rats at 7-9 weeks were intraperitoneal injection of streptozotocin (STZ) (65 mg/kg), and the rats with blood glucose over 16.7 mM were used for fabraiction of skin full-thickness defect model.The skin full-thickness defects with 15 mm of diameter were fabricated after anesthesia.

value: skin tissue

tag: genotype

value: wild type

tag: treatment

value: CO-releasing hyaluronic acid hydrogel

tag: Sex

value: male

tag: strain

value: SD


title: RNA-seq of Arabidopsis leaves's ZT21at 35DAS_batch2

city: daegu

first: myeonghoon

last: kang

state: Daegu

country: South Korea

institute: Daegu Gyeongbuk Institute of Science and Technology (DGIST)

data_processing:
Filtered reads were aligned to the Arabidopsis thaliana  genome (TAIR10) using the aligner STAR v.2.3.0e with the default option.
The tool htseq-count of Python package Htseq was used to count the mapped fragments for annotated genes.
Trimmed mean of M-values (TMM) algorithm was used to normalize raw read counts using edgeR v3.12.1
Assembly: Arabidopsis thaliana  genome (TAIR10)
Supplementary files format and content: xls file include FPKM of each conditions

organism: Arabidopsis thaliana

source_name: 3rd-4th rosette leaves

growth_protocol: Plants were grown in a growth chamber at 22 °C under a 16 h light/8 h dark cycle (long day; LD 16:8) with a light intensity of 100 μmol m−2 s−1 white light.

extract_protocol:
Total RNA isolated from third and fourth rosette leaves at ZT 1,5,9,13,17 and 21 from 21 DAS or 35 DAS aged Col-0 plants was used.
TruSeq™ RNA Library Preparation Kit (Illumina, CA, USA) . Library construction and sequencing were carried out by THERAGEN BIO (Korea) with Illumina NovaSeq6000 (Illumina ,CA, USA).

value: 3rd-4th rosette leaves


title: Untreated

description: 10x Genomics

value: untreated


title: RNA-seq of Arabidopsis leaves's ZT21at 35DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT21at 35DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT17at 35DAS_batch3


title: HAG

description: 10x Genomics

value: hyaluronic acid hydrogel


title: RNA-seq of Arabidopsis leaves's ZT17at 35DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT13 at 35DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT13 at 35DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT13 at 35DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT17at 35DAS_batch2


title: High Calorie, Day 5, 18C, WT, Rep 1, ZT10


title: RNA-seq of Arabidopsis leaves's ZT9 at 35DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT9 at 35DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT1 at 35DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT1 at 35DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT5 at 35DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT5 at 35DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT21at 21DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT21at 21DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT17at 21DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT1 at 35DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT9 at 35DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT17at 21DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT13 at 21DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT17at 21DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT13 at 21DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT21at 21DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT13 at 21DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT9 at 21DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT9 at 21DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT9 at 21DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT5 at 21DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT5 at 21DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT5 at 21DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT1 at 21DAS_batch3


title: RNA-seq of Arabidopsis leaves's ZT1 at 21DAS_batch1


title: RNA-seq of Arabidopsis leaves's ZT1 at 21DAS_batch2


title: RNA-seq of Arabidopsis leaves's ZT5 at 35DAS_batch1


title: fhm_els_cpf_MCP1

city: Sainte-Anne-de-Bellevue

first: Niladri

last: Basu

state: Quebec

address: 21,1111 Lakeshore Blvd, Apt #2

country: Canada

institute: McGill University

data_processing:
Reads were aligned using the Seq2Fun algorithm which translates raw reads to protein orthologs and maps them to a high-resolution protein-ortholog database - EcoOmicsDB available at www.expressanalyst.ca. The filtering parameters are provided below
Filtering: N. of amino acid mismatches was set at 2
Filtering: Minimum matching length was set at 19
Filtering: Minimum matching score was set at 80
Assembly: Mapping was species agnostic. Translated reads were mapped to the Vertebrate database
Raw fastq files were filtered as mentioned above and provided count matrices. These were analyzed for gene expression and pathway enrichment analysis.
Raw files and count files are provided as fastq files and .txt files, respectively.
Supplementary files format and content: Files here are from 49 datasets (datasets column below). Each dataset has a processed file which contains the counts for all samples within that dataset. Hence all samples (with unique title) from a dataset is present in the corresponding processed file. The title of the raw file for each sample is provided below as well. Some exposures were conducted together and hence had a common control exposure. Hence while 776 libraries are listed, they will correspond to fewer fastq files. But all fastq files are present.

organism: Pimephales promelas

source_name: embryo

extract_protocol:
RNA was extracted from Japanese quail and Double-crested cormorant samples using the Qiagen RNeasy mini kits; RNA was extracted from the fathead minnow, rainbow trout, African-clawed frog and the northern leopard frog using the Qiagen RNeasy Universal Mini kit.
Library was prepared according to Illumina instructions for NovaSeq 6000 S4 PE100 or HiSeq 4000 PE100 101-bp paired-end reads.

tag: lifestage

value: els

value: embryo

tag: chemical

value: cpf

tag: concentration

value: MED


title: fhm_els_cpf_MBP1


title: fhm_els_cpf_MDP1


title: fhm_els_cpf_HBP1

value: HIGH


title: fhm_els_cpf_SAP1

value: dmso

value: CTRL


title: fhm_els_cpf_SDP1


title: fhm_els_cpf_SCP1


title: fhm_els_cpf_MAP1


title: fhm_els_cpf_SEP1


title: fhm_els_cpf_HAP1


title: fhm_els_cpf_SBP1


title: fhm_els_cpf_HCP1


title: fhm_els_cpf_HEP1


title: fhm_els_cpf_HDP1


title: fhm_els_cpf_MEP1


title: fhm_els_flx_CE


title: fhm_els_flx_MA

value: flx


title: fhm_els_flx_CA


title: fhm_els_flx_HA


title: fhm_els_flx_CC


title: fhm_els_flx_MD


title: fhm_els_flx_HC


title: fhm_els_flx_MB


title: fhm_els_flx_CD


title: fhm_els_flx_ME


title: fhm_els_flx_MC


title: fhm_els_flx_HE


title: fhm_els_ee2_SEP1


title: fhm_els_flx_CB


title: fhm_els_flx_HD


title: fhm_els_ee2_SBP1


title: fhm_els_ee2_SAP1


title: fhm_els_ee2_MCP1


title: fhm_els_ee2_MDP1


title: fhm_els_ee2_MBP1


title: fhm_els_ee2_MAP1


title: fhm_els_ee2_MEP1


title: fhm_els_ee2_HCP1


title: fhm_els_ee2_HDP1


title: fhm_els_ee2_HEP1


title: fhm_els_ee2_SDP1


title: fhm_els_ee2_HBP1


title: fhm_els_ee2_HAP1


title: TP0001651D04_7_30.000000uM_PRF.DMEM_24h_TC00283227_H06

city: RTP

first: Logan

middle: J

last: Everett

state: North Carolina

address: 109 T.W. Alexander Dr

department: Office of Research and Development

institute: U.S. Environmental Protection Agency

description:
TP0001651D04_7_30.000000uM_PRF.DMEM_24h
TC00283227_H06

data_processing:
Each FASTQ file was aligned to the probe sequences in the hWTv1 assay using HISAT2 v2.1.0 with spliced alignment disabled.
Aligned reads in SAM format were processed with SAMtools v1.9 to compute the number of uniquely aligned reads for each probe. Probe counts and associated meta-data for each well were stored for analysis using MongoDB v3.6.14.
Assembly: hWTv1
Supplementary files format and content: Processed data provided as a single table of counts for all probes x all samples

organism: Homo sapiens

source_name: MCF7 Cells

growth_protocol: Five vials of cryopreserved MCF7 (HTB-22TM) cells were purchased from American Tissue Culture Collection, designated as passage 0 (P0) and stored in vapor phase liquid nitrogen prior to initial thawing and expansion. A passage 3 (P3) MCF7 cryostock was generated by thawing and pooling all five original source vials and culturing through three consecutive passages in complete growth medium (DMEM + 10% FBS + 1% PSG). At each passage, cells from different culture vessels were pooled prior to re-seeding for subsequent expansion. At P3, cells were cryopreserved at 4 million cells per mL in complete growth medium + 5% DMSO according to manufacturer’s protocol. MCF7 cultures used in all phases of this study were maintained in humidified incubators with 5% CO2 atmosphere and internal temperature of 37°C. For chemical screening, MCF7 cells were thawed and subjected to a uniform expansion protocol from P3 to P6 through increasingly larger sizes of tissue culture vessels (T25 to T75 to T225) prior to plating in 384-well format. The three cultures were initiated on consecutive days and subject to uniform handling procedures to ensure that dosing and sample collection also occurred on consecutive days. All chemical screening experiments were performed on P7 cells.

extract_protocol:
Six hours after chemical treatment, HTTr assay plates were removed from the incubator and media in each assay well was drained to a residual volume of 10 µL using MultiFlo FX microdispenser equipped with a vacuum-driven aspiration manifold. To create cell lysates, 10 µL volumes of 2X BioSpyder lysis buffer were dispensed into each assay well using the same MultiFlo FX instrument equipped with 1 µL peristaltic pump dispensing cassette. Then, 20 µL volumes of UHRR, HBRR, BLDSMO, BLTSA and Lysis Buffer reference material were manually dispensed into duplicate wells of column 1 of each assay plate. The plates were sealed with an adhesive aluminum plate cover and incubated at room temperature, protected from light, for 30 minutes. The plates were then stored at -80°C prior to shipment to BioSpyder, Inc.
Samples were analyzed by BioSpyder using a custom-attenuated version of the TempO-Seq human whole transcriptome version 1 (hWTv1) assay, which includes 21,111 probes covering 19,287 genes. Lysates were processed as described in (House et al. 2017). In brief, 2 µL of each lysate was hybridized with 2 µL of detector oligos from the hWTv1 assay using the following thermal cycler protocol: 10 min at 70°C, followed by gradual decrease to 45°C over 49 min, terminating with 45°C incubation for 16-24 hours. Excess oligos were then removed via nuclease digestion (90 min at 37°C) and hybridized detector oligos were ligated (60 min at 37°) following respective additions of 24 µL TempO-Seq nuclease and ligation mixes. RNA/DNA duplexes were then heat-denatured and 10 µL of each ligation product was transferred to an amplification microplate containing 10 µL of PCR master mix per well. Ligation products were then uniquely labeled during product amplification (10 min at 37°C, 2 min at 95°C, 6 cycles of 95°C for 30 s, 54°C for 30 s, 72°C for 120 s, 16 cycles of 95°C for 30s and 72°C for 120s, followed by 72°C for 60 s) with well coordinate-specific “barcoded” primer pairs containing universal adaptors for sequencing. Samples were then pooled into a series of three sequencing libraries (1 for each plate). Pooled sequencing libraries were then distributed across multiple lanes of a HiSeq dual flow cell and analyzed on a HiSeq 2500 Ultra-High-Throughput Sequencing System (Illumina, San Diego, CA).

treatment_protocol: DMSO-solubilized chemical stock solutions were received frozen from the US EPA ToxCast chemical inventory management contractor (EvoTec, Princeton, NJ) and stored at -80°C prior to dose plate preparation. An eight-point dilution series (1/2 log10 spacing) of test chemicals was prepared in a LabCyte Echo-qualified 384-well polypropylene (384PP) plate at 200x the desired nominal test concentration for screening (0.03 – 100 µM). Singleton wells of dosing solutions for each test chemical concentration were arrayed in columns 2 through 23 of the dose plate (Figure 1A). Transcriptomics reference chemicals (genistein, trichostatin A, sirolimus) were solubilized as 200x dosing solutions corresponding to nominal test concentrations of 10, 1 and 0.1 µM, respectively. Triplicate wells of dosing solutions for each of the transcriptomic reference chemicals were added to the dose plate (column 24) along with quadruplicate wells of pure DMSO as a vehicle control. At 24 h post-plating, 200 nL of 200x dosing solutions were transferred to the assay plates using a LabCyte Echo 550 acoustic dispenser. The final concentration of DMSO in all treatment, reference treatment and vehicle control wells was 0.5%.  Well coordinates on each assay plate were uniquely randomized with respect to treatment so that any potential edge-well effects were distributed in an unbiased manner across all possible treatment conditions.

tag: cell line

tag: media

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 30 uM of Clofibrate

tag: chemical name

value: Clofibrate

tag: chemical sample id

tag: chemical concentration

value: 30 uM

tag: dose level

tag: exposure time

tag: assay plate

tag: assay plate well


title: TP0001651A05_5_3.000000uM_PRF.DMEM_24h_TC00283227_H04

description:
TP0001651A05_5_3.000000uM_PRF.DMEM_24h
TC00283227_H04

value: 24h exposure of 3 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)

value: 3 uM


title: TP0001651D01_2_0.100000uM_PRF.DMEM_24h_TC00283227_H03

description:
TP0001651D01_2_0.100000uM_PRF.DMEM_24h
TC00283227_H03

value: 24h exposure of 0.1 uM of Lactofen

value: Lactofen


title: TP0001651E03_3_0.300000uM_PRF.DMEM_24h_TC00283227_H07

description:
TP0001651E03_3_0.300000uM_PRF.DMEM_24h
TC00283227_H07

value: 24h exposure of 0.3 uM of Prochloraz

value: Prochloraz


title: TP0001651H03_6_10.000000uM_PRF.DMEM_24h_TC00283227_G23

description:
TP0001651H03_6_10.000000uM_PRF.DMEM_24h
TC00283227_G23

value: 24h exposure of 10 uM of Fomesafen

value: Fomesafen

value: 10 uM


title: fhm_els_ee2_SCP1

value: els

tag: tissue

value: embryo

value: dmso


title: TP0001651A04_8_100.000000uM_PRF.DMEM_24h_TC00283227_H05

description:
TP0001651A04_8_100.000000uM_PRF.DMEM_24h
TC00283227_H05

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 100 uM of Rotenone

value: Rotenone


title: TP0001651C04_6_10.000000uM_PRF.DMEM_24h_TC00283227_G24

description:
TP0001651C04_6_10.000000uM_PRF.DMEM_24h
TC00283227_G24

value: 24h exposure of 10 uM of Simvastatin

value: Simvastatin


title: TP0001651F01_2_0.100000uM_PRF.DMEM_24h_TC00283227_H02

description:
TP0001651F01_2_0.100000uM_PRF.DMEM_24h
TC00283227_H02

value: 24h exposure of 0.1 uM of Tetrac

value: Tetrac


title: BL_TSA_TC00283227_H01

description:
BL_TSA
TC00283227_H01

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A

value: 1 uM


title: TP0001651F03_2_0.100000uM_PRF.DMEM_24h_TC00283227_G22

description:
TP0001651F03_2_0.100000uM_PRF.DMEM_24h
TC00283227_G22

value: 24h exposure of 0.1 uM of 4-Cumylphenol


title: TP0001651H04_1_0.030000uM_PRF.DMEM_24h_TC00283227_G16

description:
TP0001651H04_1_0.030000uM_PRF.DMEM_24h
TC00283227_G16

value: 24h exposure of 0.03 uM of Bisphenol A

value: Bisphenol A


title: TP0001651H02_7_30.000000uM_PRF.DMEM_24h_TC00283227_G17

description:
TP0001651H02_7_30.000000uM_PRF.DMEM_24h
TC00283227_G17

value: 24h exposure of 30 uM of Maneb

value: Maneb

value: 30 uM


title: TP0001651B01_8_100.000000uM_PRF.DMEM_24h_TC00283227_G18

description:
TP0001651B01_8_100.000000uM_PRF.DMEM_24h
TC00283227_G18

value: 24h exposure of 100 uM of Cyanazine

value: Cyanazine


title: TP0001651B03_7_30.000000uM_PRF.DMEM_24h_TC00283227_G13

description:
TP0001651B03_7_30.000000uM_PRF.DMEM_24h
TC00283227_G13

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 30 uM of Reserpine

value: Reserpine


title: TP0001651B02_3_0.300000uM_PRF.DMEM_24h_TC00283227_G21

description:
TP0001651B02_3_0.300000uM_PRF.DMEM_24h
TC00283227_G21

value: 24h exposure of 0.3 uM of 3,5,3'-Triiodothyronine


title: TP0001651A02_2_0.100000uM_PRF.DMEM_24h_TC00283227_G15

description:
TP0001651A02_2_0.100000uM_PRF.DMEM_24h
TC00283227_G15

value: 24h exposure of 0.1 uM of Imazalil

value: Imazalil


title: TP0001651A01_7_30.000000uM_PRF.DMEM_24h_TC00283227_G14

description:
TP0001651A01_7_30.000000uM_PRF.DMEM_24h
TC00283227_G14

value: 24h exposure of 30 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651D05_3_0.300000uM_PRF.DMEM_24h_TC00283227_G19

description:
TP0001651D05_3_0.300000uM_PRF.DMEM_24h
TC00283227_G19

value: 24h exposure of 0.3 uM of Thiram

value: Thiram


title: fhm_els_flx_HB

value: els

value: embryo

value: flx

value: HIGH


title: TP0001651E01_7_30.000000uM_PRF.DMEM_24h_TC00283227_G09

description:
TP0001651E01_7_30.000000uM_PRF.DMEM_24h
TC00283227_G09

value: 24h exposure of 30 uM of Bifenthrin

value: Bifenthrin

value: 30 uM


title: TP0001651A05_1_0.030000uM_PRF.DMEM_24h_TC00283227_G10

description:
TP0001651A05_1_0.030000uM_PRF.DMEM_24h
TC00283227_G10

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.03 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651B04_7_30.000000uM_PRF.DMEM_24h_TC00283227_G20

description:
TP0001651B04_7_30.000000uM_PRF.DMEM_24h
TC00283227_G20

value: 24h exposure of 30 uM of Propiconazole

value: Propiconazole


title: TP0001651G01_2_0.100000uM_PRF.DMEM_24h_TC00283227_G08

description:
TP0001651G01_2_0.100000uM_PRF.DMEM_24h
TC00283227_G08

value: 24h exposure of 0.1 uM of Vinclozolin

value: Vinclozolin


title: TP0001651H05_1_0.030000uM_PRF.DMEM_24h_TC00283227_G11

description:
TP0001651H05_1_0.030000uM_PRF.DMEM_24h
TC00283227_G11

value: 24h exposure of 0.03 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651G02_7_30.000000uM_PRF.DMEM_24h_TC00283227_G06

description:
TP0001651G02_7_30.000000uM_PRF.DMEM_24h
TC00283227_G06

value: 24h exposure of 30 uM of Lovastatin

value: Lovastatin


title: TP0001651B01_4_1.000000uM_PRF.DMEM_24h_TC00283227_G07

description:
TP0001651B01_4_1.000000uM_PRF.DMEM_24h
TC00283227_G07

value: 24h exposure of 1 uM of Cyanazine

value: Cyanazine

value: 1 uM


title: TP0001651A02_4_1.000000uM_PRF.DMEM_24h_TC00283227_G03

description:
TP0001651A02_4_1.000000uM_PRF.DMEM_24h
TC00283227_G03

value: 24h exposure of 1 uM of Imazalil

value: Imazalil


title: TP0001651E04_4_1.000000uM_PRF.DMEM_24h_TC00283227_G04

description:
TP0001651E04_4_1.000000uM_PRF.DMEM_24h
TC00283227_G04

value: 24h exposure of 1 uM of Farglitazar

value: Farglitazar


title: TP0001651C02_4_1.000000uM_PRF.DMEM_24h_TC00283227_G02

description:
TP0001651C02_4_1.000000uM_PRF.DMEM_24h
TC00283227_G02

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 1 uM of 4-Hydroxytamoxifen


title: TP0001651H01_3_0.300000uM_PRF.DMEM_24h_TC00283227_F22

description:
TP0001651H01_3_0.300000uM_PRF.DMEM_24h
TC00283227_F22

value: 24h exposure of 0.3 uM of Flutamide

value: Flutamide


title: TP0001651F04_5_3.000000uM_PRF.DMEM_24h_TC00283227_F23

description:
TP0001651F04_5_3.000000uM_PRF.DMEM_24h
TC00283227_F23

value: 24h exposure of 3 uM of Fulvestrant

value: Fulvestrant

value: 3 uM


title: TP0001651F01_5_3.000000uM_PRF.DMEM_24h_TC00283227_F20

description:
TP0001651F01_5_3.000000uM_PRF.DMEM_24h
TC00283227_F20

value: 24h exposure of 3 uM of Tetrac

value: Tetrac


title: TP0001651B04_6_10.000000uM_PRF.DMEM_24h_TC00283227_F18

description:
TP0001651B04_6_10.000000uM_PRF.DMEM_24h
TC00283227_F18

value: 24h exposure of 10 uM of Propiconazole

value: Propiconazole

value: 10 uM


title: TP0001651A04_2_0.100000uM_PRF.DMEM_24h_TC00283227_F17

description:
TP0001651A04_2_0.100000uM_PRF.DMEM_24h
TC00283227_F17

value: 24h exposure of 0.1 uM of Rotenone

value: Rotenone


title: TP0001651H02_2_0.100000uM_PRF.DMEM_24h_TC00283227_F16

description:
TP0001651H02_2_0.100000uM_PRF.DMEM_24h
TC00283227_F16

value: 24h exposure of 0.1 uM of Maneb

value: Maneb


title: TP0001651E05_5_3.000000uM_PRF.DMEM_24h_TC00283227_G05

description:
TP0001651E05_5_3.000000uM_PRF.DMEM_24h
TC00283227_G05

value: 24h exposure of 3 uM of Atrazine

value: Atrazine


title: TP0001651D03_8_100.000000uM_PRF.DMEM_24h_TC00283227_F12

description:
TP0001651D03_8_100.000000uM_PRF.DMEM_24h
TC00283227_F12

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 100 uM of Cypermethrin

value: Cypermethrin


title: TP0001651B05_5_3.000000uM_PRF.DMEM_24h_TC00283227_F15

description:
TP0001651B05_5_3.000000uM_PRF.DMEM_24h
TC00283227_F15

value: 24h exposure of 3 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651D04_6_10.000000uM_PRF.DMEM_24h_TC00283227_F14

description:
TP0001651D04_6_10.000000uM_PRF.DMEM_24h
TC00283227_F14

value: 24h exposure of 10 uM of Clofibrate

value: Clofibrate


title: TP0001651H03_5_3.000000uM_PRF.DMEM_24h_TC00283227_F13

description:
TP0001651H03_5_3.000000uM_PRF.DMEM_24h
TC00283227_F13

value: 24h exposure of 3 uM of Fomesafen

value: Fomesafen

value: 3 uM


title: TP0001651C03_5_3.000000uM_PRF.DMEM_24h_TC00283227_F09

description:
TP0001651C03_5_3.000000uM_PRF.DMEM_24h
TC00283227_F09

value: 24h exposure of 3 uM of Simazine

value: Simazine


title: TP0001651A04_3_0.300000uM_PRF.DMEM_24h_TC00283227_F24

description:
TP0001651A04_3_0.300000uM_PRF.DMEM_24h
TC00283227_F24

value: 24h exposure of 0.3 uM of Rotenone

value: Rotenone


title: TP0001651F03_5_3.000000uM_PRF.DMEM_24h_TC00283227_F11

description:
TP0001651F03_5_3.000000uM_PRF.DMEM_24h
TC00283227_F11

value: 24h exposure of 3 uM of 4-Cumylphenol


title: TP0001651E02_4_1.000000uM_PRF.DMEM_24h_TC00283227_F08

description:
TP0001651E02_4_1.000000uM_PRF.DMEM_24h
TC00283227_F08

value: 24h exposure of 1 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched

value: 1 uM


title: TP0001651E02_7_30.000000uM_PRF.DMEM_24h_TC00283227_F21

description:
TP0001651E02_7_30.000000uM_PRF.DMEM_24h
TC00283227_F21

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 30 uM of 4-Nonylphenol, branched

value: 30 uM


title: BL_DMSO_TC00283227_F01

description:
BL_DMSO
TC00283227_F01

value: untreated

value: 0 uM


title: TP0001651H05_6_10.000000uM_PRF.DMEM_24h_TC00283227_F05

description:
TP0001651H05_6_10.000000uM_PRF.DMEM_24h
TC00283227_F05

value: 24h exposure of 10 uM of Trifloxystrobin

value: Trifloxystrobin

value: 10 uM


title: TP0001651B01_3_0.300000uM_PRF.DMEM_24h_TC00283227_F03

description:
TP0001651B01_3_0.300000uM_PRF.DMEM_24h
TC00283227_F03

value: 24h exposure of 0.3 uM of Cyanazine

value: Cyanazine


title: SIRO_PRF.DMEM_24h_TC00283227_F07

description:
SIRO_PRF.DMEM_24h
TC00283227_F07

value: 6h exposure of 0.1 uM of Sirolimus

value: Sirolimus


title: TP0001651D04_4_1.000000uM_PRF.DMEM_24h_TC00283227_F02

description:
TP0001651D04_4_1.000000uM_PRF.DMEM_24h
TC00283227_F02

value: 24h exposure of 1 uM of Clofibrate

value: Clofibrate


title: TP0001651F03_8_100.000000uM_PRF.DMEM_24h_TC00283227_F06

description:
TP0001651F03_8_100.000000uM_PRF.DMEM_24h
TC00283227_F06

value: 24h exposure of 100 uM of 4-Cumylphenol


title: BL_TSA_TC00283227_G01

description:
BL_TSA
TC00283227_G01

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A


title: TP0001651H05_3_0.300000uM_PRF.DMEM_24h_TC00283227_F19

description:
TP0001651H05_3_0.300000uM_PRF.DMEM_24h
TC00283227_F19

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.3 uM of Trifloxystrobin


title: TP0001651H02_1_0.030000uM_PRF.DMEM_24h_TC00283227_E23

description:
TP0001651H02_1_0.030000uM_PRF.DMEM_24h
TC00283227_E23

value: 24h exposure of 0.03 uM of Maneb

value: Maneb


title: TP0001651B03_1_0.030000uM_PRF.DMEM_24h_TC00283227_E24

description:
TP0001651B03_1_0.030000uM_PRF.DMEM_24h
TC00283227_E24

value: 24h exposure of 0.03 uM of Reserpine

value: Reserpine


title: TP0001651C04_2_0.100000uM_PRF.DMEM_24h_TC00283227_E21

description:
TP0001651C04_2_0.100000uM_PRF.DMEM_24h
TC00283227_E21

value: 24h exposure of 0.1 uM of Simvastatin

value: Simvastatin


title: TP0001651D02_1_0.030000uM_PRF.DMEM_24h_TC00283227_E19

description:
TP0001651D02_1_0.030000uM_PRF.DMEM_24h
TC00283227_E19

value: 24h exposure of 0.03 uM of PFOA

value: PFOA


title: TP0001651C02_8_100.000000uM_PRF.DMEM_24h_TC00283227_E20

description:
TP0001651C02_8_100.000000uM_PRF.DMEM_24h
TC00283227_E20

value: 24h exposure of 100 uM of 4-Hydroxytamoxifen


title: TP0001651D06_6_10.000000uM_PRF.DMEM_24h_TC00283227_E22

description:
TP0001651D06_6_10.000000uM_PRF.DMEM_24h
TC00283227_E22

value: 24h exposure of 10 uM of PFOS

value: PFOS

value: 10 uM


title: TP0001651F04_1_0.030000uM_PRF.DMEM_24h_TC00283227_E17

description:
TP0001651F04_1_0.030000uM_PRF.DMEM_24h
TC00283227_E17

value: 24h exposure of 0.03 uM of Fulvestrant

value: Fulvestrant


title: TP0001651E03_7_30.000000uM_PRF.DMEM_24h_TC00283227_E18

description:
TP0001651E03_7_30.000000uM_PRF.DMEM_24h
TC00283227_E18

value: 24h exposure of 30 uM of Prochloraz

value: Prochloraz

value: 30 uM


title: TP0001651G03_7_30.000000uM_PRF.DMEM_24h_TC00283227_F10

description:
TP0001651G03_7_30.000000uM_PRF.DMEM_24h
TC00283227_F10

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 30 uM of Nilutamide

value: Nilutamide


title: TP0001651E02_8_100.000000uM_PRF.DMEM_24h_TC00283227_E16

description:
TP0001651E02_8_100.000000uM_PRF.DMEM_24h
TC00283227_E16

value: 24h exposure of 100 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651C02_7_30.000000uM_PRF.DMEM_24h_TC00283227_E14

description:
TP0001651C02_7_30.000000uM_PRF.DMEM_24h
TC00283227_E14

value: 24h exposure of 30 uM of 4-Hydroxytamoxifen


title: DMSO_PRF.DMEM_24h_TC00283227_E12

description:
DMSO_PRF.DMEM_24h
TC00283227_E12

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651A01_2_0.100000uM_PRF.DMEM_24h_TC00283227_F04

description:
TP0001651A01_2_0.100000uM_PRF.DMEM_24h
TC00283227_F04

value: 24h exposure of 0.1 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651E04_8_100.000000uM_PRF.DMEM_24h_TC00283227_E15

description:
TP0001651E04_8_100.000000uM_PRF.DMEM_24h
TC00283227_E15

value: 24h exposure of 100 uM of Farglitazar

value: Farglitazar


title: Control_WT_2_PB-TRE-3XFLAG-DUXBL_NoDOX_FLAG_rep1

city: Bethesda

first: Desiree

last: Tillo

state: MD

address: 41 Center Dr, Room D310

institute: NIH/NCI

library_source: genomic

data_processing:
Basecalling was performed using bcl2fastq version 2.20.0
Data were processed using a modified version of Cut&RunTools (Zhu et al., 2019).  Reads were adapter trimmed using fastp v.0.20.0 (Chen et al., 2018).  An additional trimming step was performed to remove up to 6bp adapter from each read.
Trimmed reads were aligned to a hybrid mm10 and E. coli (MG1655) genome using bowtie2 (Langmead et al., 2012) with the ‘dovetail’ and ‘sensitive’ settings enabled.  Aligned fragments were segregated into mouse and carry-over (E. coli) subsets.
Normalized reads per genomic signal (RPGC) signal tracks were generated from the mouse alignments using the ‘bamCoverage’ utility from deepTools (Ramirez et al., 2016) with parameters  bin-size=25, smooth length=75, and with ‘center_reads’ and ‘extend_reads’ options enabled.
Assembly: mm10
Supplementary files format and content: bigwig files containing reads per genomic content (RGPC) normalized read density.
Library strategy: CUT&RUN

molecule: genomic DNA

organism: Mus musculus

source_name: Embryonic Stem Cells

growth_protocol: ESC were grown on 0.1% gelatin-coated plates or alternatively on a feeder layer of growth-arrested MEFs in high-glucose DMEM (Gibco) supplemented with 15% FBS, 1:500 LIF (made in house), 0.1 mM non-essential amino acids, 1% glutamax, 1mM Sodium Pyruvate, 55 mM β-mercaptoethanol, and 1% penicillin/streptomycin (all from ThermoFisher Scientific) at 37°C and 5% CO2.

extract_protocol:
The CUT&RUN protocol was slightly modified from (Skene et al., 2018; Meers et al., 2019). In brief, cells were washed thrice with Wash Buffer (20 mM HEPES-KOH pH 7.5, 150 mM NaCl, 0.5 mM spermidine, Roche complete Protease Inhibitor tablet EDTA free) and bound to activated Concanavalin A beads (Polysciences) for 10 minutes at room temperature. Cells were then permeabilized in Digitonin Buffer (0.05 % Digitonin and 0.1% BSA in Wash Buffer) and incubated with corresponding antibodies at 4°C for 2 hours. For negative controls, Guinea Pig anti-Rabbit IgG (Antibodies-online) was used. Following antibody incubation, cells were washed with Digitonin Buffer and incubated with a hybrid protein A-protein G-Micrococcal nuclease (pAG-MNase) at 4°C for 1 hour. Samples were washed in Digitonin Buffer, resuspended in 150 μl Digitonin Buffer and equilibrated to 0°C on ice water for 5 minutes. To initiate MNase cleavage, 3 μl 100 mM CaCl2 was added to cells and after 1 hour of digestion, reactions were stopped with the addition of 150 μl 2x Stop Buffer (340 mM NaCl, 20 mM EDTA, 4 mM EGTA, 0.02 % Digitonin, 50 μg/ml RNase A, 50 μg/ml Glycogen). Samples were incubated at 37°C for 10 minutes to release DNA fragments and centrifuged at 16,000 g for 5 minutes. Supernatants were collected and a mix of 1.5 μl 20% SDS / 2.25 μl 20 mg/ml Proteinase K was added to each sample and incubated at 65°C for 35 minutes. DNA was precipitated with ethanol and sodium acetate and pelleted by high-speed centrifugation at 4°C, washed, air-dried and resuspended in 10 μ 0.1x TE.
The entire precipitated DNA obtained from CUT&RUN was used to prepare Illumina compatible sequencing libraries. In brief, end-repair was performed in 50 μl of T4 ligase reaction buffer, 0.4 mM dNTPs, 3 U of T4 DNA polymerase (NEB), 9 U of T4 Polynucleotide Kinase (NEB) and 1 U of Klenow fragment (NEB) at 20°C for 30 minutes. End-repair reaction was cleaned using AMPure XP beads (Beckman Coulter) and eluted in 16.5 μl of Elution Buffer (10 mM Tris-HCl pH 8.5) followed by A-tailing reaction in 20 μl of dA-Tailing reaction buffer (NEB) with 2.5 U of Klenow fragment exo- (NEB) at 37°C for 30 minutes. The 20 μl of the A-tailing reaction were mixed with Quick Ligase buffer 2X (NEB), 3000 U of Quick Ligase (NEB) and 10 nM of annealed adaptor (Illumina truncated adaptor) in a volume of 50 μl and incubated at room temperature for 20 min. The adaptor was prepared by annealing the following HPLC-purified oligos: 5′-Phos/GATCGGAAGAGCACACGTCT-3′ and 5′-ACACTCTTTCCCTACACGACGCTCTTCCGATC∗T-3′ (∗phosphorothioate bond). Ligation was stopped by adding 50 mM of EDTA, cleaned with AMPure XP beads and eluted in 14 μl of Elution Buffer. All volume was used for PCR amplification in a 50 μl reaction with 1 μM primers TruSeq barcoded primer p7, 5′-CAAGCAGAAGACGGCATACGAGATXXXXXXXXGTGACTGGAGTTCAGACGTGTGCTCTTCCGATC∗T-3′ and TruSeq barcoded primer p5 5′-AATGATACGGCGACCACCGAGATCTACACXXXXXXXXACACTCTTTCCCTACACGACGCTCTTCCGATC*T-3′ (∗ represents a phosphothiorate bond and XXXXXXXX a barcode index sequence), and 2X Kapa HiFi HotStart Ready mix (Kapa Biosciences). The temperature settings during the PCR amplification were 45 s at 98°C followed by 15 cycles of 15 s at 98°C, 30 s at 63°C, 30 s at 72°C and a final 5 min extension at 72°C. PCR reactions were cleaned with AMPure XP beads (Beckman Coulter), run on a 2% agarose gel and a band of 300bp approximately was cut and gel purified using QIAquick Gel Extraction Kit (QIAGEN). Library concentration was determined with KAPA Library Quantification Kit for Illumina Platforms (Kapa Biosystems). Sequencing was performed on the Illumina NextSeq500 (75bp pair-end reads) or NextSeq2000 (60bp pair-end reads).

treatment_protocol: DOX for 16 hours, Pladienolide B for 24 hours

value: Embryonic Stem Cells

tag: cell type

tag: genotype

value: WT

tag: antibody

value: anti-FLAG (Sigma-Aldrich Cat# F1804, RRID:AB_262044)


title: TP0001651F02_3_0.300000uM_PRF.DMEM_24h_TC00283227_E11

description:
TP0001651F02_3_0.300000uM_PRF.DMEM_24h
TC00283227_E11

tag: treatment

value: 24h exposure of 0.3 uM of Ziram

value: Ziram


title: TP0001651H01_2_0.100000uM_PRF.DMEM_24h_TC00283227_G12

description:
TP0001651H01_2_0.100000uM_PRF.DMEM_24h
TC00283227_G12

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.1 uM of Flutamide

value: Flutamide


title: TP0001651D02_3_0.300000uM_PRF.DMEM_24h_TC00283227_E10

description:
TP0001651D02_3_0.300000uM_PRF.DMEM_24h
TC00283227_E10

value: 24h exposure of 0.3 uM of PFOA

value: PFOA


title: TP0001651C06_4_1.000000uM_PRF.DMEM_24h_TC00283227_E08

description:
TP0001651C06_4_1.000000uM_PRF.DMEM_24h
TC00283227_E08

value: 24h exposure of 1 uM of Cycloheximide

value: Cycloheximide

value: 1 uM


title: TP0001651G05_6_10.000000uM_PRF.DMEM_24h_TC00283227_E09

description:
TP0001651G05_6_10.000000uM_PRF.DMEM_24h
TC00283227_E09

value: 24h exposure of 10 uM of Cyproterone acetate

value: Cyproterone acetate

value: 10 uM


title: TP0001651H01_4_1.000000uM_PRF.DMEM_24h_TC00283227_E07

description:
TP0001651H01_4_1.000000uM_PRF.DMEM_24h
TC00283227_E07

value: 24h exposure of 1 uM of Flutamide


title: TP0001651H02_5_3.000000uM_PRF.DMEM_24h_TC00283227_E05

description:
TP0001651H02_5_3.000000uM_PRF.DMEM_24h
TC00283227_E05

value: 24h exposure of 3 uM of Maneb

value: Maneb

value: 3 uM


title: TP0001651F01_1_0.030000uM_PRF.DMEM_24h_TC00283227_E06

description:
TP0001651F01_1_0.030000uM_PRF.DMEM_24h
TC00283227_E06

value: 24h exposure of 0.03 uM of Tetrac

value: Tetrac


title: TSA_PRF.DMEM_24h_TC00283227_E04

description:
TSA_PRF.DMEM_24h
TC00283227_E04

value: DMEM + 10% charcoal-stripped FBS

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A


title: TP0001651B03_6_10.000000uM_PRF.DMEM_24h_TC00283227_E02

description:
TP0001651B03_6_10.000000uM_PRF.DMEM_24h
TC00283227_E02

value: 24h exposure of 10 uM of Reserpine

value: Reserpine


title: TP0001651D03_6_10.000000uM_PRF.DMEM_24h_TC00283227_D21

description:
TP0001651D03_6_10.000000uM_PRF.DMEM_24h
TC00283227_D21

value: 24h exposure of 10 uM of Cypermethrin

value: Cypermethrin


title: TP0001651A03_4_1.000000uM_PRF.DMEM_24h_TC00283227_D23

description:
TP0001651A03_4_1.000000uM_PRF.DMEM_24h
TC00283227_D23

value: 24h exposure of 1 uM of Butafenacil

value: Butafenacil

value: 1 uM


title: TP0001651F02_8_100.000000uM_PRF.DMEM_24h_TC00283227_D22

description:
TP0001651F02_8_100.000000uM_PRF.DMEM_24h
TC00283227_D22

value: 24h exposure of 100 uM of Ziram

value: Ziram


title: TP0001651B03_4_1.000000uM_PRF.DMEM_24h_TC00283227_D24

description:
TP0001651B03_4_1.000000uM_PRF.DMEM_24h
TC00283227_D24

value: 24h exposure of 1 uM of Reserpine


title: TP0001651C06_1_0.030000uM_PRF.DMEM_24h_TC00283227_D20

description:
TP0001651C06_1_0.030000uM_PRF.DMEM_24h
TC00283227_D20

value: 24h exposure of 0.03 uM of Cycloheximide

value: Cycloheximide


title: TP0001651D04_3_0.300000uM_PRF.DMEM_24h_TC00283227_D17

description:
TP0001651D04_3_0.300000uM_PRF.DMEM_24h
TC00283227_D17

value: 24h exposure of 0.3 uM of Clofibrate

value: Clofibrate


title: TP0001651E05_3_0.300000uM_PRF.DMEM_24h_TC00283227_D18

description:
TP0001651E05_3_0.300000uM_PRF.DMEM_24h
TC00283227_D18

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.3 uM of Atrazine

value: Atrazine


title: TP0001651E02_3_0.300000uM_PRF.DMEM_24h_TC00283227_D16

description:
TP0001651E02_3_0.300000uM_PRF.DMEM_24h
TC00283227_D16

value: 24h exposure of 0.3 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: GEN_PRF.DMEM_24h_TC00283227_D15

description:
GEN_PRF.DMEM_24h
TC00283227_D15

value: 6h exposure of 10 uM of Genistein

value: Genistein

value: 10 uM


title: TP0001651D04_5_3.000000uM_PRF.DMEM_24h_TC00283227_E13

description:
TP0001651D04_5_3.000000uM_PRF.DMEM_24h
TC00283227_E13

value: 24h exposure of 3 uM of Clofibrate

value: 3 uM


title: TP0001651G04_5_3.000000uM_PRF.DMEM_24h_TC00283227_D13

description:
TP0001651G04_5_3.000000uM_PRF.DMEM_24h
TC00283227_D13

value: 24h exposure of 3 uM of Cladribine

value: Cladribine


title: TP0001651A01_6_10.000000uM_PRF.DMEM_24h_TC00283227_D14

description:
TP0001651A01_6_10.000000uM_PRF.DMEM_24h
TC00283227_D14

value: 24h exposure of 10 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651B04_4_1.000000uM_PRF.DMEM_24h_TC00283227_D12

description:
TP0001651B04_4_1.000000uM_PRF.DMEM_24h
TC00283227_D12

value: 24h exposure of 1 uM of Propiconazole

value: Propiconazole

value: 1 uM


title: TP0001651E02_5_3.000000uM_PRF.DMEM_24h_TC00283227_D11

description:
TP0001651E02_5_3.000000uM_PRF.DMEM_24h
TC00283227_D11

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 3 uM of 4-Nonylphenol, branched


title: TP0001651C03_3_0.300000uM_PRF.DMEM_24h_TC00283227_E03

description:
TP0001651C03_3_0.300000uM_PRF.DMEM_24h
TC00283227_E03

value: 24h exposure of 0.3 uM of Simazine

value: Simazine


title: TP0001651C06_5_3.000000uM_PRF.DMEM_24h_TC00283227_D08

description:
TP0001651C06_5_3.000000uM_PRF.DMEM_24h
TC00283227_D08

value: 24h exposure of 3 uM of Cycloheximide

value: Cycloheximide


title: BL_DMSO_TC00283227_E01

description:
BL_DMSO
TC00283227_E01

value: untreated

value: 0 uM


title: TP0001651A04_5_3.000000uM_PRF.DMEM_24h_TC00283227_D10

description:
TP0001651A04_5_3.000000uM_PRF.DMEM_24h
TC00283227_D10

value: 24h exposure of 3 uM of Rotenone

value: Rotenone


title: TP0001651B04_2_0.100000uM_PRF.DMEM_24h_TC00283227_C24

description:
TP0001651B04_2_0.100000uM_PRF.DMEM_24h
TC00283227_C24

value: 24h exposure of 0.1 uM of Propiconazole


title: TP0001651E01_3_0.300000uM_PRF.DMEM_24h_TC00283227_D06

description:
TP0001651E01_3_0.300000uM_PRF.DMEM_24h
TC00283227_D06

value: 24h exposure of 0.3 uM of Bifenthrin

value: Bifenthrin


title: TP0001651E05_1_0.030000uM_PRF.DMEM_24h_TC00283227_D05

description:
TP0001651E05_1_0.030000uM_PRF.DMEM_24h
TC00283227_D05

value: 24h exposure of 0.03 uM of Atrazine

value: Atrazine


title: TP0001651A03_5_3.000000uM_PRF.DMEM_24h_TC00283227_D19

description:
TP0001651A03_5_3.000000uM_PRF.DMEM_24h
TC00283227_D19

value: 24h exposure of 3 uM of Butafenacil

value: Butafenacil

value: 3 uM


title: TP0001651E02_2_0.100000uM_PRF.DMEM_24h_TC00283227_D02

description:
TP0001651E02_2_0.100000uM_PRF.DMEM_24h
TC00283227_D02

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.1 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: HBRR_TC00283227_D01

description:
HBRR
TC00283227_D01

source_name: Human Brain Reference RNA


title: TP0001651C04_8_100.000000uM_PRF.DMEM_24h_TC00283227_C22

description:
TP0001651C04_8_100.000000uM_PRF.DMEM_24h
TC00283227_C22

value: 24h exposure of 100 uM of Simvastatin

value: Simvastatin


title: TP0001651C06_7_30.000000uM_PRF.DMEM_24h_TC00283227_C19

description:
TP0001651C06_7_30.000000uM_PRF.DMEM_24h
TC00283227_C19

value: 24h exposure of 30 uM of Cycloheximide

value: Cycloheximide

value: 30 uM


title: TP0001651G05_5_3.000000uM_PRF.DMEM_24h_TC00283227_C20

description:
TP0001651G05_5_3.000000uM_PRF.DMEM_24h
TC00283227_C20

value: 24h exposure of 3 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651A04_6_10.000000uM_PRF.DMEM_24h_TC00283227_C21

description:
TP0001651A04_6_10.000000uM_PRF.DMEM_24h
TC00283227_C21

value: 24h exposure of 10 uM of Rotenone

value: Rotenone

value: 10 uM


title: TP0001651G02_5_3.000000uM_PRF.DMEM_24h_TC00283227_C17

description:
TP0001651G02_5_3.000000uM_PRF.DMEM_24h
TC00283227_C17

value: 24h exposure of 3 uM of Lovastatin

value: Lovastatin


title: TP0001651G03_5_3.000000uM_PRF.DMEM_24h_TC00283227_C18

description:
TP0001651G03_5_3.000000uM_PRF.DMEM_24h
TC00283227_C18

value: 24h exposure of 3 uM of Nilutamide

value: Nilutamide


title: TP0001651G03_1_0.030000uM_PRF.DMEM_24h_TC00283227_C14

description:
TP0001651G03_1_0.030000uM_PRF.DMEM_24h
TC00283227_C14

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.03 uM of Nilutamide


title: TP0001651G05_1_0.030000uM_PRF.DMEM_24h_TC00283227_C13

description:
TP0001651G05_1_0.030000uM_PRF.DMEM_24h
TC00283227_C13

value: 24h exposure of 0.03 uM of Cyproterone acetate


title: TP0001651B01_5_3.000000uM_PRF.DMEM_24h_TC00283227_C12

description:
TP0001651B01_5_3.000000uM_PRF.DMEM_24h
TC00283227_C12

value: 24h exposure of 3 uM of Cyanazine

value: Cyanazine

value: 3 uM


title: TP0001651D01_6_10.000000uM_PRF.DMEM_24h_TC00283227_D09

description:
TP0001651D01_6_10.000000uM_PRF.DMEM_24h
TC00283227_D09

value: 24h exposure of 10 uM of Lactofen

value: Lactofen


title: DMSO_PRF.DMEM_24h_TC00283227_C11

description:
DMSO_PRF.DMEM_24h
TC00283227_C11

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651F05_5_3.000000uM_PRF.DMEM_24h_TC00283227_C10

description:
TP0001651F05_5_3.000000uM_PRF.DMEM_24h
TC00283227_C10

value: 24h exposure of 3 uM of Fenofibrate

value: Fenofibrate


title: TP0001651C02_6_10.000000uM_PRF.DMEM_24h_TC00283227_D07

description:
TP0001651C02_6_10.000000uM_PRF.DMEM_24h
TC00283227_D07

value: 24h exposure of 10 uM of 4-Hydroxytamoxifen

value: 10 uM


title: TP0001651B05_1_0.030000uM_PRF.DMEM_24h_TC00283227_C08

description:
TP0001651B05_1_0.030000uM_PRF.DMEM_24h
TC00283227_C08

value: 24h exposure of 0.03 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651H05_4_1.000000uM_PRF.DMEM_24h_TC00283227_D03

description:
TP0001651H05_4_1.000000uM_PRF.DMEM_24h
TC00283227_D03

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 1 uM of Trifloxystrobin

value: Trifloxystrobin

value: 1 uM


title: TP0001651H02_4_1.000000uM_PRF.DMEM_24h_TC00283227_D04

description:
TP0001651H02_4_1.000000uM_PRF.DMEM_24h
TC00283227_D04

value: 24h exposure of 1 uM of Maneb

value: Maneb


title: TP0001651D06_1_0.030000uM_PRF.DMEM_24h_TC00283227_C06

description:
TP0001651D06_1_0.030000uM_PRF.DMEM_24h
TC00283227_C06

value: 24h exposure of 0.03 uM of PFOS

value: PFOS


title: TP0001651C05_4_1.000000uM_PRF.DMEM_24h_TC00283227_C04

description:
TP0001651C05_4_1.000000uM_PRF.DMEM_24h
TC00283227_C04

value: 24h exposure of 1 uM of Bisphenol B

value: Bisphenol B


title: TP0001651F04_8_100.000000uM_PRF.DMEM_24h_TC00283227_C07

description:
TP0001651F04_8_100.000000uM_PRF.DMEM_24h
TC00283227_C07

value: 24h exposure of 100 uM of Fulvestrant

value: Fulvestrant


title: TP0001651C06_8_100.000000uM_PRF.DMEM_24h_TC00283227_C05

description:
TP0001651C06_8_100.000000uM_PRF.DMEM_24h
TC00283227_C05

value: 24h exposure of 100 uM of Cycloheximide

value: Cycloheximide


title: TP0001651A01_4_1.000000uM_PRF.DMEM_24h_TC00283227_C23

description:
TP0001651A01_4_1.000000uM_PRF.DMEM_24h
TC00283227_C23

value: 24h exposure of 1 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651G04_7_30.000000uM_PRF.DMEM_24h_TC00283227_C02

description:
TP0001651G04_7_30.000000uM_PRF.DMEM_24h
TC00283227_C02

value: 24h exposure of 30 uM of Cladribine

value: Cladribine

value: 30 uM


title: TP0001651G01_4_1.000000uM_PRF.DMEM_24h_TC00283227_C16

description:
TP0001651G01_4_1.000000uM_PRF.DMEM_24h
TC00283227_C16

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 1 uM of Vinclozolin

value: Vinclozolin


title: TP0001651H04_3_0.300000uM_PRF.DMEM_24h_TC00283227_C15

description:
TP0001651H04_3_0.300000uM_PRF.DMEM_24h
TC00283227_C15

value: 24h exposure of 0.3 uM of Bisphenol A

value: Bisphenol A


title: TP0001651B04_3_0.300000uM_PRF.DMEM_24h_TC00283227_C03

description:
TP0001651B04_3_0.300000uM_PRF.DMEM_24h
TC00283227_C03

value: 24h exposure of 0.3 uM of Propiconazole

value: Propiconazole


title: HBRR_TC00283227_C01

description:
HBRR
TC00283227_C01

value: untreated


title: TP0001651C03_7_30.000000uM_PRF.DMEM_24h_TC00283227_B21

description:
TP0001651C03_7_30.000000uM_PRF.DMEM_24h
TC00283227_B21

value: 24h exposure of 30 uM of Simazine

value: Simazine


title: TP0001651F05_2_0.100000uM_PRF.DMEM_24h_TC00283227_B24

description:
TP0001651F05_2_0.100000uM_PRF.DMEM_24h
TC00283227_B24

value: 24h exposure of 0.1 uM of Fenofibrate

value: Fenofibrate


title: TP0001651C06_3_0.300000uM_PRF.DMEM_24h_TC00283227_B23

description:
TP0001651C06_3_0.300000uM_PRF.DMEM_24h
TC00283227_B23

value: 24h exposure of 0.3 uM of Cycloheximide

value: Cycloheximide


title: TP0001651F02_7_30.000000uM_PRF.DMEM_24h_TC00283227_C09

description:
TP0001651F02_7_30.000000uM_PRF.DMEM_24h
TC00283227_C09

value: 24h exposure of 30 uM of Ziram

value: Ziram


title: TP0001651A06_1_0.030000uM_PRF.DMEM_24h_TC00283227_B22

description:
TP0001651A06_1_0.030000uM_PRF.DMEM_24h
TC00283227_B22

value: 24h exposure of 0.03 uM of Cyproconazole

value: Cyproconazole


title: TP0001651E04_3_0.300000uM_PRF.DMEM_24h_TC00283227_B19

description:
TP0001651E04_3_0.300000uM_PRF.DMEM_24h
TC00283227_B19

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.3 uM of Farglitazar

value: Farglitazar


title: TP0001651C04_1_0.030000uM_PRF.DMEM_24h_TC00283227_B13

description:
TP0001651C04_1_0.030000uM_PRF.DMEM_24h
TC00283227_B13

value: 24h exposure of 0.03 uM of Simvastatin

value: Simvastatin


title: TP0001651F04_2_0.100000uM_PRF.DMEM_24h_TC00283227_B16

description:
TP0001651F04_2_0.100000uM_PRF.DMEM_24h
TC00283227_B16

value: 24h exposure of 0.1 uM of Fulvestrant

value: Fulvestrant


title: TP0001651F02_4_1.000000uM_PRF.DMEM_24h_TC00283227_B15

description:
TP0001651F02_4_1.000000uM_PRF.DMEM_24h
TC00283227_B15

value: 24h exposure of 1 uM of Ziram

value: 1 uM


title: TP0001651G02_6_10.000000uM_PRF.DMEM_24h_TC00283227_B12

description:
TP0001651G02_6_10.000000uM_PRF.DMEM_24h
TC00283227_B12

value: 24h exposure of 10 uM of Lovastatin

value: Lovastatin

value: 10 uM


title: TP0001651A05_7_30.000000uM_PRF.DMEM_24h_TC00283227_B18

description:
TP0001651A05_7_30.000000uM_PRF.DMEM_24h
TC00283227_B18

value: 24h exposure of 30 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)

value: 30 uM


title: TP0001651H02_8_100.000000uM_PRF.DMEM_24h_TC00283227_B17

description:
TP0001651H02_8_100.000000uM_PRF.DMEM_24h
TC00283227_B17

value: 24h exposure of 100 uM of Maneb

value: Maneb


title: TP0001651D03_5_3.000000uM_PRF.DMEM_24h_TC00283227_B10

description:
TP0001651D03_5_3.000000uM_PRF.DMEM_24h
TC00283227_B10

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 3 uM of Cypermethrin

value: Cypermethrin

value: 3 uM


title: TP0001651H03_3_0.300000uM_PRF.DMEM_24h_TC00283227_B11

description:
TP0001651H03_3_0.300000uM_PRF.DMEM_24h
TC00283227_B11

value: 24h exposure of 0.3 uM of Fomesafen

value: Fomesafen


title: TP0001651A01_3_0.300000uM_PRF.DMEM_24h_TC00283227_B08

description:
TP0001651A01_3_0.300000uM_PRF.DMEM_24h
TC00283227_B08

value: 24h exposure of 0.3 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651D02_5_3.000000uM_PRF.DMEM_24h_TC00283227_B06

description:
TP0001651D02_5_3.000000uM_PRF.DMEM_24h
TC00283227_B06

value: 24h exposure of 3 uM of PFOA

value: PFOA


title: TP0001651H05_8_100.000000uM_PRF.DMEM_24h_TC00283227_B02

description:
TP0001651H05_8_100.000000uM_PRF.DMEM_24h
TC00283227_B02

value: 24h exposure of 100 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651E02_1_0.030000uM_PRF.DMEM_24h_TC00283227_B09

description:
TP0001651E02_1_0.030000uM_PRF.DMEM_24h
TC00283227_B09

value: 24h exposure of 0.03 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651F02_1_0.030000uM_PRF.DMEM_24h_TC00283227_B05

description:
TP0001651F02_1_0.030000uM_PRF.DMEM_24h
TC00283227_B05

value: 24h exposure of 0.03 uM of Ziram

value: Ziram


title: TP0001651D05_1_0.030000uM_PRF.DMEM_24h_TC00283227_B07

description:
TP0001651D05_1_0.030000uM_PRF.DMEM_24h
TC00283227_B07

value: 24h exposure of 0.03 uM of Thiram

value: Thiram


title: TP0001651B06_3_0.300000uM_PRF.DMEM_24h_TC00283227_B14

description:
TP0001651B06_3_0.300000uM_PRF.DMEM_24h
TC00283227_B14

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 0.3 uM of Troglitazone

value: Troglitazone


title: TP0001651G04_4_1.000000uM_PRF.DMEM_24h_TC00283227_B04

description:
TP0001651G04_4_1.000000uM_PRF.DMEM_24h
TC00283227_B04

value: 24h exposure of 1 uM of Cladribine

value: Cladribine

value: 1 uM


title: TP0001651G02_4_1.000000uM_PRF.DMEM_24h_TC00283227_B20

description:
TP0001651G02_4_1.000000uM_PRF.DMEM_24h
TC00283227_B20

value: 24h exposure of 1 uM of Lovastatin

value: Lovastatin


title: UHRR_TC00283227_B01

description:
UHRR
TC00283227_B01

source_name: Universal Human Reference RNA

value: untreated


title: TP0001651D05_8_100.000000uM_PRF.DMEM_24h_TC00283227_A24

description:
TP0001651D05_8_100.000000uM_PRF.DMEM_24h
TC00283227_A24

value: 24h exposure of 100 uM of Thiram


title: TP0001651D02_7_30.000000uM_PRF.DMEM_24h_TC00283227_B03

description:
TP0001651D02_7_30.000000uM_PRF.DMEM_24h
TC00283227_B03

value: 24h exposure of 30 uM of PFOA

value: PFOA

value: 30 uM


title: TP0001651G03_8_100.000000uM_PRF.DMEM_24h_TC00283227_A22

description:
TP0001651G03_8_100.000000uM_PRF.DMEM_24h
TC00283227_A22

value: 24h exposure of 100 uM of Nilutamide

value: Nilutamide


title: TP0001651H02_6_10.000000uM_PRF.DMEM_24h_TC00283227_A21

description:
TP0001651H02_6_10.000000uM_PRF.DMEM_24h
TC00283227_A21

value: 24h exposure of 10 uM of Maneb

value: Maneb

value: 10 uM


title: TP0001651E03_4_1.000000uM_PRF.DMEM_24h_TC00283227_A23

description:
TP0001651E03_4_1.000000uM_PRF.DMEM_24h
TC00283227_A23

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 1 uM of Prochloraz

value: Prochloraz


title: TP0001651B03_2_0.100000uM_PRF.DMEM_24h_TC00283227_A18

description:
TP0001651B03_2_0.100000uM_PRF.DMEM_24h
TC00283227_A18

value: 24h exposure of 0.1 uM of Reserpine

value: Reserpine


title: TP0001651D06_2_0.100000uM_PRF.DMEM_24h_TC00283227_A17

description:
TP0001651D06_2_0.100000uM_PRF.DMEM_24h
TC00283227_A17

value: 24h exposure of 0.1 uM of PFOS

value: PFOS


title: TP0001651A03_1_0.030000uM_PRF.DMEM_24h_TC00283227_A20

description:
TP0001651A03_1_0.030000uM_PRF.DMEM_24h
TC00283227_A20

value: 24h exposure of 0.03 uM of Butafenacil

value: Butafenacil


title: TP0001651G05_2_0.100000uM_PRF.DMEM_24h_TC00283227_A15

description:
TP0001651G05_2_0.100000uM_PRF.DMEM_24h
TC00283227_A15

value: 24h exposure of 0.1 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651D02_2_0.100000uM_PRF.DMEM_24h_TC00283227_A14

description:
TP0001651D02_2_0.100000uM_PRF.DMEM_24h
TC00283227_A14

value: 24h exposure of 0.1 uM of PFOA

value: PFOA


title: TP0001651D04_1_0.030000uM_PRF.DMEM_24h_TC00283227_A16

description:
TP0001651D04_1_0.030000uM_PRF.DMEM_24h
TC00283227_A16

value: 24h exposure of 0.03 uM of Clofibrate

value: Clofibrate


title: TP0001651G01_5_3.000000uM_PRF.DMEM_24h_TC00283227_A12

description:
TP0001651G01_5_3.000000uM_PRF.DMEM_24h
TC00283227_A12

value: 24h exposure of 3 uM of Vinclozolin

value: Vinclozolin

value: 3 uM


title: TP0001651H04_8_100.000000uM_PRF.DMEM_24h_TC00283227_A11

description:
TP0001651H04_8_100.000000uM_PRF.DMEM_24h
TC00283227_A11

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 100 uM of Bisphenol A

value: Bisphenol A


title: TP0001651B02_6_10.000000uM_PRF.DMEM_24h_TC00283227_A13

description:
TP0001651B02_6_10.000000uM_PRF.DMEM_24h
TC00283227_A13

value: 24h exposure of 10 uM of 3,5,3'-Triiodothyronine

value: 10 uM


title: TP0001651A04_1_0.030000uM_PRF.DMEM_24h_TC00283227_A10

description:
TP0001651A04_1_0.030000uM_PRF.DMEM_24h
TC00283227_A10

value: 24h exposure of 0.03 uM of Rotenone

value: Rotenone


title: TP0001651B03_8_100.000000uM_PRF.DMEM_24h_TC00283227_A08

description:
TP0001651B03_8_100.000000uM_PRF.DMEM_24h
TC00283227_A08

value: 24h exposure of 100 uM of Reserpine

value: Reserpine


title: TP0001651B06_8_100.000000uM_PRF.DMEM_24h_TC00283227_A07

description:
TP0001651B06_8_100.000000uM_PRF.DMEM_24h
TC00283227_A07

value: 24h exposure of 100 uM of Troglitazone

value: Troglitazone


title: TP0001651C03_4_1.000000uM_PRF.DMEM_24h_TC00283227_A04

description:
TP0001651C03_4_1.000000uM_PRF.DMEM_24h
TC00283227_A04

value: 24h exposure of 1 uM of Simazine

value: Simazine

value: 1 uM


title: UHRR_TC00283227_A01

description:
UHRR
TC00283227_A01

value: untreated


title: TP0001651A03_7_30.000000uM_PRF.DMEM_24h_TC00283227_A05

description:
TP0001651A03_7_30.000000uM_PRF.DMEM_24h
TC00283227_A05

value: 24h exposure of 30 uM of Butafenacil

value: Butafenacil

value: 30 uM


title: TP0001651E04_7_30.000000uM_PRF.DMEM_24h_TC00283227_A06

description:
TP0001651E04_7_30.000000uM_PRF.DMEM_24h
TC00283227_A06

value: DMEM + 10% charcoal-stripped FBS

value: 24h exposure of 30 uM of Farglitazar

value: Farglitazar


title: TP0001651G03_7_30.000000uM_PRF.DMEM_12h_TC00283224_P23

description:
TP0001651G03_7_30.000000uM_PRF.DMEM_12h
TC00283224_P23

value: 12h exposure of 30 uM of Nilutamide

value: Nilutamide


title: TP0001651B02_7_30.000000uM_PRF.DMEM_24h_TC00283227_A02

description:
TP0001651B02_7_30.000000uM_PRF.DMEM_24h
TC00283227_A02

value: 24h exposure of 30 uM of 3,5,3'-Triiodothyronine


title: TP0001651A02_4_1.000000uM_PRF.DMEM_12h_TC00283224_P24

description:
TP0001651A02_4_1.000000uM_PRF.DMEM_12h
TC00283224_P24

value: 12h exposure of 1 uM of Imazalil

value: Imazalil


title: TP0001651B06_5_3.000000uM_PRF.DMEM_24h_TC00283227_A03

description:
TP0001651B06_5_3.000000uM_PRF.DMEM_24h
TC00283227_A03

value: 24h exposure of 3 uM of Troglitazone

value: 3 uM


title: TP0001651B06_6_10.000000uM_PRF.DMEM_24h_TC00283227_A19

description:
TP0001651B06_6_10.000000uM_PRF.DMEM_24h
TC00283227_A19

value: 24h exposure of 10 uM of Troglitazone

value: Troglitazone

value: 10 uM


title: TP0001651D04_6_10.000000uM_PRF.DMEM_12h_TC00283224_P22

description:
TP0001651D04_6_10.000000uM_PRF.DMEM_12h
TC00283224_P22

value: 12h exposure of 10 uM of Clofibrate

value: Clofibrate


title: TP0001651G05_4_1.000000uM_PRF.DMEM_12h_TC00283224_P21

description:
TP0001651G05_4_1.000000uM_PRF.DMEM_12h
TC00283224_P21

value: 12h exposure of 1 uM of Cyproterone acetate

value: Cyproterone acetate

value: 1 uM


title: TP0001651G01_1_0.030000uM_PRF.DMEM_12h_TC00283224_P20

description:
TP0001651G01_1_0.030000uM_PRF.DMEM_12h
TC00283224_P20

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.03 uM of Vinclozolin

value: Vinclozolin


title: TP0001651B05_4_1.000000uM_PRF.DMEM_12h_TC00283224_P19

description:
TP0001651B05_4_1.000000uM_PRF.DMEM_12h
TC00283224_P19

value: 12h exposure of 1 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651C04_1_0.030000uM_PRF.DMEM_12h_TC00283224_P15

description:
TP0001651C04_1_0.030000uM_PRF.DMEM_12h
TC00283224_P15

value: 12h exposure of 0.03 uM of Simvastatin

value: Simvastatin


title: TP0001651A05_1_0.030000uM_PRF.DMEM_12h_TC00283224_P17

description:
TP0001651A05_1_0.030000uM_PRF.DMEM_12h
TC00283224_P17

value: 12h exposure of 0.03 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651B02_8_100.000000uM_PRF.DMEM_12h_TC00283224_P13

description:
TP0001651B02_8_100.000000uM_PRF.DMEM_12h
TC00283224_P13

value: 12h exposure of 100 uM of 3,5,3'-Triiodothyronine


title: TP0001651B01_4_1.000000uM_PRF.DMEM_12h_TC00283224_P18

description:
TP0001651B01_4_1.000000uM_PRF.DMEM_12h
TC00283224_P18

value: 12h exposure of 1 uM of Cyanazine

value: Cyanazine


title: TP0001651C06_6_10.000000uM_PRF.DMEM_12h_TC00283224_P14

description:
TP0001651C06_6_10.000000uM_PRF.DMEM_12h
TC00283224_P14

value: 12h exposure of 10 uM of Cycloheximide

value: Cycloheximide

value: 10 uM


title: TP0001651E02_6_10.000000uM_PRF.DMEM_12h_TC00283224_P12

description:
TP0001651E02_6_10.000000uM_PRF.DMEM_12h
TC00283224_P12

value: 12h exposure of 10 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: TP0001651B04_4_1.000000uM_PRF.DMEM_12h_TC00283224_P10

description:
TP0001651B04_4_1.000000uM_PRF.DMEM_12h
TC00283224_P10

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 1 uM of Propiconazole

value: Propiconazole

value: 1 uM


title: TP0001651F04_3_0.300000uM_PRF.DMEM_12h_TC00283224_P11

description:
TP0001651F04_3_0.300000uM_PRF.DMEM_12h
TC00283224_P11

value: 12h exposure of 0.3 uM of Fulvestrant

value: Fulvestrant


title: TP0001651C05_5_3.000000uM_PRF.DMEM_12h_TC00283224_P09

description:
TP0001651C05_5_3.000000uM_PRF.DMEM_12h
TC00283224_P09

value: 12h exposure of 3 uM of Bisphenol B

value: Bisphenol B

value: 3 uM


title: TSA_PRF.DMEM_24h_TC00283227_A09

description:
TSA_PRF.DMEM_24h
TC00283227_A09

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A


title: TP0001651H05_1_0.030000uM_PRF.DMEM_12h_TC00283224_P08

description:
TP0001651H05_1_0.030000uM_PRF.DMEM_12h
TC00283224_P08

value: 12h exposure of 0.03 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651F02_4_1.000000uM_PRF.DMEM_12h_TC00283224_P06

description:
TP0001651F02_4_1.000000uM_PRF.DMEM_12h
TC00283224_P06

value: 12h exposure of 1 uM of Ziram

value: Ziram


title: TP0001651F04_2_0.100000uM_PRF.DMEM_12h_TC00283224_P04

description:
TP0001651F04_2_0.100000uM_PRF.DMEM_12h
TC00283224_P04

value: 12h exposure of 0.1 uM of Fulvestrant


title: TP0001651C03_7_30.000000uM_PRF.DMEM_12h_TC00283224_P03

description:
TP0001651C03_7_30.000000uM_PRF.DMEM_12h
TC00283224_P03

value: 12h exposure of 30 uM of Simazine

value: Simazine

value: 30 uM


title: TP0001651C03_6_10.000000uM_PRF.DMEM_12h_TC00283224_P07

description:
TP0001651C03_6_10.000000uM_PRF.DMEM_12h
TC00283224_P07

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 10 uM of Simazine

value: 10 uM


title: TP0001651G01_4_1.000000uM_PRF.DMEM_12h_TC00283224_P05

description:
TP0001651G01_4_1.000000uM_PRF.DMEM_12h
TC00283224_P05

value: 12h exposure of 1 uM of Vinclozolin

value: Vinclozolin

value: 1 uM


title: TP0001651A03_2_0.100000uM_PRF.DMEM_12h_TC00283224_P02

description:
TP0001651A03_2_0.100000uM_PRF.DMEM_12h
TC00283224_P02

value: 12h exposure of 0.1 uM of Butafenacil

value: Butafenacil


title: TP0001651F03_1_0.030000uM_PRF.DMEM_12h_TC00283224_O24

description:
TP0001651F03_1_0.030000uM_PRF.DMEM_12h
TC00283224_O24

value: 12h exposure of 0.03 uM of 4-Cumylphenol


title: TP0001651B05_5_3.000000uM_PRF.DMEM_12h_TC00283224_O23

description:
TP0001651B05_5_3.000000uM_PRF.DMEM_12h
TC00283224_O23

value: 12h exposure of 3 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride

value: 3 uM


title: TP0001651E01_8_100.000000uM_PRF.DMEM_12h_TC00283224_P16

description:
TP0001651E01_8_100.000000uM_PRF.DMEM_12h
TC00283224_P16

value: 12h exposure of 100 uM of Bifenthrin

value: Bifenthrin


title: TP0001651D02_3_0.300000uM_PRF.DMEM_12h_TC00283224_O22

description:
TP0001651D02_3_0.300000uM_PRF.DMEM_12h
TC00283224_O22

value: 12h exposure of 0.3 uM of PFOA

value: PFOA


title: TP0001651E04_4_1.000000uM_PRF.DMEM_12h_TC00283224_O19

description:
TP0001651E04_4_1.000000uM_PRF.DMEM_12h
TC00283224_O19

value: 12h exposure of 1 uM of Farglitazar

value: Farglitazar


title: TP0001651B05_7_30.000000uM_PRF.DMEM_12h_TC00283224_O18

description:
TP0001651B05_7_30.000000uM_PRF.DMEM_12h
TC00283224_O18

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 30 uM of Amiodarone hydrochloride

value: 30 uM


title: TP0001651B04_8_100.000000uM_PRF.DMEM_12h_TC00283224_O20

description:
TP0001651B04_8_100.000000uM_PRF.DMEM_12h
TC00283224_O20

value: 12h exposure of 100 uM of Propiconazole

value: Propiconazole


title: TP0001651C03_3_0.300000uM_PRF.DMEM_12h_TC00283224_O17

description:
TP0001651C03_3_0.300000uM_PRF.DMEM_12h
TC00283224_O17

value: 12h exposure of 0.3 uM of Simazine

value: Simazine


title: TP0001651G04_8_100.000000uM_PRF.DMEM_12h_TC00283224_O16

description:
TP0001651G04_8_100.000000uM_PRF.DMEM_12h
TC00283224_O16

value: 12h exposure of 100 uM of Cladribine

value: Cladribine


title: TP0001651C05_7_30.000000uM_PRF.DMEM_12h_TC00283224_O15

description:
TP0001651C05_7_30.000000uM_PRF.DMEM_12h
TC00283224_O15

value: 12h exposure of 30 uM of Bisphenol B

value: Bisphenol B


title: TP0001651D04_8_100.000000uM_PRF.DMEM_12h_TC00283224_O11

description:
TP0001651D04_8_100.000000uM_PRF.DMEM_12h
TC00283224_O11

value: 12h exposure of 100 uM of Clofibrate

value: Clofibrate


title: TP0001651D05_6_10.000000uM_PRF.DMEM_12h_TC00283224_O08

description:
TP0001651D05_6_10.000000uM_PRF.DMEM_12h
TC00283224_O08

value: 12h exposure of 10 uM of Thiram

value: Thiram

value: 10 uM


title: GEN_PRF.DMEM_12h_TC00283224_O12

description:
GEN_PRF.DMEM_12h
TC00283224_O12

value: 6h exposure of 10 uM of Genistein

value: Genistein


title: TP0001651F03_7_30.000000uM_PRF.DMEM_12h_TC00283224_O13

description:
TP0001651F03_7_30.000000uM_PRF.DMEM_12h
TC00283224_O13

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 30 uM of 4-Cumylphenol


title: TP0001651F05_3_0.300000uM_PRF.DMEM_12h_TC00283224_O09

description:
TP0001651F05_3_0.300000uM_PRF.DMEM_12h
TC00283224_O09

value: 12h exposure of 0.3 uM of Fenofibrate

value: Fenofibrate


title: SIRO_PRF.DMEM_12h_TC00283224_O10

description:
SIRO_PRF.DMEM_12h
TC00283224_O10

value: 6h exposure of 0.1 uM of Sirolimus

value: Sirolimus


title: TP0001651B05_8_100.000000uM_PRF.DMEM_12h_TC00283224_O06

description:
TP0001651B05_8_100.000000uM_PRF.DMEM_12h
TC00283224_O06

value: 12h exposure of 100 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651D06_1_0.030000uM_PRF.DMEM_12h_TC00283224_O14

description:
TP0001651D06_1_0.030000uM_PRF.DMEM_12h
TC00283224_O14

value: 12h exposure of 0.03 uM of PFOS

value: PFOS


title: TP0001651A02_8_100.000000uM_PRF.DMEM_12h_TC00283224_O04

description:
TP0001651A02_8_100.000000uM_PRF.DMEM_12h
TC00283224_O04

value: 12h exposure of 100 uM of Imazalil

value: Imazalil


title: TP0001651E02_7_30.000000uM_PRF.DMEM_12h_TC00283224_O07

description:
TP0001651E02_7_30.000000uM_PRF.DMEM_12h
TC00283224_O07

value: 12h exposure of 30 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched

value: 30 uM


title: TP0001651E03_4_1.000000uM_PRF.DMEM_12h_TC00283224_O03

description:
TP0001651E03_4_1.000000uM_PRF.DMEM_12h
TC00283224_O03

value: 12h exposure of 1 uM of Prochloraz

value: Prochloraz

value: 1 uM


title: TP0001651D03_6_10.000000uM_PRF.DMEM_12h_TC00283224_N22

description:
TP0001651D03_6_10.000000uM_PRF.DMEM_12h
TC00283224_N22

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 10 uM of Cypermethrin

value: Cypermethrin

value: 10 uM


title: TP0001651A01_5_3.000000uM_PRF.DMEM_12h_TC00283224_O21

description:
TP0001651A01_5_3.000000uM_PRF.DMEM_12h
TC00283224_O21

value: 12h exposure of 3 uM of Pyraclostrobin

value: Pyraclostrobin

value: 3 uM


title: TP0001651E04_1_0.030000uM_PRF.DMEM_12h_TC00283224_N24

description:
TP0001651E04_1_0.030000uM_PRF.DMEM_12h
TC00283224_N24

value: 12h exposure of 0.03 uM of Farglitazar

value: Farglitazar


title: TP0001651A03_6_10.000000uM_PRF.DMEM_12h_TC00283224_N23

description:
TP0001651A03_6_10.000000uM_PRF.DMEM_12h
TC00283224_N23

value: 12h exposure of 10 uM of Butafenacil

value: Butafenacil


title: TP0001651F03_2_0.100000uM_PRF.DMEM_12h_TC00283224_N20

description:
TP0001651F03_2_0.100000uM_PRF.DMEM_12h
TC00283224_N20

value: 12h exposure of 0.1 uM of 4-Cumylphenol


title: TP0001651D02_4_1.000000uM_PRF.DMEM_12h_TC00283224_O02

description:
TP0001651D02_4_1.000000uM_PRF.DMEM_12h
TC00283224_O02

value: 12h exposure of 1 uM of PFOA

value: PFOA


title: TP0001651H02_4_1.000000uM_PRF.DMEM_12h_TC00283224_N19

description:
TP0001651H02_4_1.000000uM_PRF.DMEM_12h
TC00283224_N19

value: 12h exposure of 1 uM of Maneb

value: Maneb


title: TP0001651B01_5_3.000000uM_PRF.DMEM_12h_TC00283224_N18

description:
TP0001651B01_5_3.000000uM_PRF.DMEM_12h
TC00283224_N18

value: 12h exposure of 3 uM of Cyanazine

value: Cyanazine


title: TP0001651C04_3_0.300000uM_PRF.DMEM_12h_TC00283224_N17

description:
TP0001651C04_3_0.300000uM_PRF.DMEM_12h
TC00283224_N17

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.3 uM of Simvastatin

value: Simvastatin


title: TP0001651E02_3_0.300000uM_PRF.DMEM_12h_TC00283224_N16

description:
TP0001651E02_3_0.300000uM_PRF.DMEM_12h
TC00283224_N16

value: 12h exposure of 0.3 uM of 4-Nonylphenol, branched

value: 4-Nonylphenol, branched


title: SIRO_PRF.DMEM_12h_TC00283224_N14

description:
SIRO_PRF.DMEM_12h
TC00283224_N14

value: 6h exposure of 0.1 uM of Sirolimus

value: Sirolimus


title: TP0001651G03_5_3.000000uM_PRF.DMEM_12h_TC00283224_N15

description:
TP0001651G03_5_3.000000uM_PRF.DMEM_12h
TC00283224_N15

value: 12h exposure of 3 uM of Nilutamide

value: Nilutamide

value: 3 uM


title: TP0001651G05_5_3.000000uM_PRF.DMEM_12h_TC00283224_N10

description:
TP0001651G05_5_3.000000uM_PRF.DMEM_12h
TC00283224_N10

value: 12h exposure of 3 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651C05_4_1.000000uM_PRF.DMEM_12h_TC00283224_N12

description:
TP0001651C05_4_1.000000uM_PRF.DMEM_12h
TC00283224_N12

value: 12h exposure of 1 uM of Bisphenol B

value: Bisphenol B

value: 1 uM


title: TP0001651C01_4_1.000000uM_PRF.DMEM_12h_TC00283224_N11

description:
TP0001651C01_4_1.000000uM_PRF.DMEM_12h
TC00283224_N11

value: 12h exposure of 1 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651H04_4_1.000000uM_PRF.DMEM_12h_TC00283224_O05

description:
TP0001651H04_4_1.000000uM_PRF.DMEM_12h
TC00283224_O05

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 1 uM of Bisphenol A

value: Bisphenol A


title: TP0001651E04_2_0.100000uM_PRF.DMEM_12h_TC00283224_N13

description:
TP0001651E04_2_0.100000uM_PRF.DMEM_12h
TC00283224_N13

value: 12h exposure of 0.1 uM of Farglitazar

value: Farglitazar


title: TP0001651H02_6_10.000000uM_PRF.DMEM_12h_TC00283224_N09

description:
TP0001651H02_6_10.000000uM_PRF.DMEM_12h
TC00283224_N09

value: 12h exposure of 10 uM of Maneb

value: Maneb

value: 10 uM


title: TP0001651D03_4_1.000000uM_PRF.DMEM_12h_TC00283224_N21

description:
TP0001651D03_4_1.000000uM_PRF.DMEM_12h
TC00283224_N21

value: 12h exposure of 1 uM of Cypermethrin

value: Cypermethrin


title: TP0001651C01_8_100.000000uM_PRF.DMEM_12h_TC00283224_N04

description:
TP0001651C01_8_100.000000uM_PRF.DMEM_12h
TC00283224_N04

value: 12h exposure of 100 uM of Fenpyroximate (Z,E)


title: TP0001651H04_6_10.000000uM_PRF.DMEM_12h_TC00283224_N05

description:
TP0001651H04_6_10.000000uM_PRF.DMEM_12h
TC00283224_N05

value: 12h exposure of 10 uM of Bisphenol A


title: TP0001651E03_5_3.000000uM_PRF.DMEM_12h_TC00283224_N06

description:
TP0001651E03_5_3.000000uM_PRF.DMEM_12h
TC00283224_N06

value: 12h exposure of 3 uM of Prochloraz

value: Prochloraz

value: 3 uM


title: TP0001651E04_6_10.000000uM_PRF.DMEM_12h_TC00283224_N08

description:
TP0001651E04_6_10.000000uM_PRF.DMEM_12h
TC00283224_N08

value: 12h exposure of 10 uM of Farglitazar


title: TP0001651A05_5_3.000000uM_PRF.DMEM_12h_TC00283224_M24

description:
TP0001651A05_5_3.000000uM_PRF.DMEM_12h
TC00283224_M24

value: 12h exposure of 3 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651B03_7_30.000000uM_PRF.DMEM_12h_TC00283224_N07

description:
TP0001651B03_7_30.000000uM_PRF.DMEM_12h
TC00283224_N07

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 30 uM of Reserpine

value: Reserpine

value: 30 uM


title: TP0001651E01_7_30.000000uM_PRF.DMEM_12h_TC00283224_N02

description:
TP0001651E01_7_30.000000uM_PRF.DMEM_12h
TC00283224_N02

value: 12h exposure of 30 uM of Bifenthrin

value: Bifenthrin


title: TP0001651A02_2_0.100000uM_PRF.DMEM_12h_TC00283224_N03

description:
TP0001651A02_2_0.100000uM_PRF.DMEM_12h
TC00283224_N03

value: 12h exposure of 0.1 uM of Imazalil

value: Imazalil


title: TP0001651G02_2_0.100000uM_PRF.DMEM_12h_TC00283224_M19

description:
TP0001651G02_2_0.100000uM_PRF.DMEM_12h
TC00283224_M19

value: 12h exposure of 0.1 uM of Lovastatin

value: Lovastatin


title: TP0001651G01_8_100.000000uM_PRF.DMEM_12h_TC00283224_M23

description:
TP0001651G01_8_100.000000uM_PRF.DMEM_12h
TC00283224_M23

value: 12h exposure of 100 uM of Vinclozolin

value: Vinclozolin


title: TP0001651D01_7_30.000000uM_PRF.DMEM_12h_TC00283224_M21

description:
TP0001651D01_7_30.000000uM_PRF.DMEM_12h
TC00283224_M21

value: 12h exposure of 30 uM of Lactofen

value: Lactofen


title: TP0001651D04_1_0.030000uM_PRF.DMEM_12h_TC00283224_M22

description:
TP0001651D04_1_0.030000uM_PRF.DMEM_12h
TC00283224_M22

value: 12h exposure of 0.03 uM of Clofibrate

value: Clofibrate


title: TP0001651C05_2_0.100000uM_PRF.DMEM_12h_TC00283224_M16

description:
TP0001651C05_2_0.100000uM_PRF.DMEM_12h
TC00283224_M16

value: 12h exposure of 0.1 uM of Bisphenol B

value: Bisphenol B


title: TP0001651B04_1_0.030000uM_PRF.DMEM_12h_TC00283224_M18

description:
TP0001651B04_1_0.030000uM_PRF.DMEM_12h
TC00283224_M18

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.03 uM of Propiconazole

value: Propiconazole


title: TP0001651G02_3_0.300000uM_PRF.DMEM_12h_TC00283224_M20

description:
TP0001651G02_3_0.300000uM_PRF.DMEM_12h
TC00283224_M20

value: 12h exposure of 0.3 uM of Lovastatin


title: TP0001651F02_7_30.000000uM_PRF.DMEM_12h_TC00283224_M14

description:
TP0001651F02_7_30.000000uM_PRF.DMEM_12h
TC00283224_M14

value: 12h exposure of 30 uM of Ziram

value: Ziram

value: 30 uM


title: TP0001651A03_3_0.300000uM_PRF.DMEM_12h_TC00283224_M17

description:
TP0001651A03_3_0.300000uM_PRF.DMEM_12h
TC00283224_M17

value: 12h exposure of 0.3 uM of Butafenacil

value: Butafenacil


title: TP0001651H02_3_0.300000uM_PRF.DMEM_12h_TC00283224_M15

description:
TP0001651H02_3_0.300000uM_PRF.DMEM_12h
TC00283224_M15

value: 12h exposure of 0.3 uM of Maneb

value: Maneb


title: TP0001651H03_6_10.000000uM_PRF.DMEM_12h_TC00283224_M13

description:
TP0001651H03_6_10.000000uM_PRF.DMEM_12h
TC00283224_M13

value: 12h exposure of 10 uM of Fomesafen

value: Fomesafen

value: 10 uM


title: TP0001651G02_6_10.000000uM_PRF.DMEM_12h_TC00283224_M11

description:
TP0001651G02_6_10.000000uM_PRF.DMEM_12h
TC00283224_M11

value: 12h exposure of 10 uM of Lovastatin

value: Lovastatin


title: TP0001651A04_1_0.030000uM_PRF.DMEM_12h_TC00283224_M10

description:
TP0001651A04_1_0.030000uM_PRF.DMEM_12h
TC00283224_M10

value: 12h exposure of 0.03 uM of Rotenone

value: Rotenone


title: TP0001651H05_2_0.100000uM_PRF.DMEM_12h_TC00283224_M09

description:
TP0001651H05_2_0.100000uM_PRF.DMEM_12h
TC00283224_M09

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.1 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651D01_6_10.000000uM_PRF.DMEM_12h_TC00283224_M07

description:
TP0001651D01_6_10.000000uM_PRF.DMEM_12h
TC00283224_M07

value: 12h exposure of 10 uM of Lactofen

value: Lactofen


title: TP0001651H03_5_3.000000uM_PRF.DMEM_12h_TC00283224_M04

description:
TP0001651H03_5_3.000000uM_PRF.DMEM_12h
TC00283224_M04

value: 12h exposure of 3 uM of Fomesafen

value: 3 uM


title: TP0001651D02_8_100.000000uM_PRF.DMEM_12h_TC00283224_M08

description:
TP0001651D02_8_100.000000uM_PRF.DMEM_12h
TC00283224_M08

value: 12h exposure of 100 uM of PFOA

value: PFOA


title: TP0001651C04_8_100.000000uM_PRF.DMEM_12h_TC00283224_M05

description:
TP0001651C04_8_100.000000uM_PRF.DMEM_12h
TC00283224_M05

value: 12h exposure of 100 uM of Simvastatin

value: Simvastatin


title: TP0001651G01_2_0.100000uM_PRF.DMEM_12h_TC00283224_M06

description:
TP0001651G01_2_0.100000uM_PRF.DMEM_12h
TC00283224_M06

value: 12h exposure of 0.1 uM of Vinclozolin

value: Vinclozolin


title: TP0001651D06_2_0.100000uM_PRF.DMEM_12h_TC00283224_M03

description:
TP0001651D06_2_0.100000uM_PRF.DMEM_12h
TC00283224_M03

value: 12h exposure of 0.1 uM of PFOS

value: PFOS


title: TP0001651G05_1_0.030000uM_PRF.DMEM_12h_TC00283224_M02

description:
TP0001651G05_1_0.030000uM_PRF.DMEM_12h
TC00283224_M02

value: 12h exposure of 0.03 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651F01_1_0.030000uM_PRF.DMEM_12h_TC00283224_L24

description:
TP0001651F01_1_0.030000uM_PRF.DMEM_12h
TC00283224_L24

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.03 uM of Tetrac

value: Tetrac


title: TP0001651A04_3_0.300000uM_PRF.DMEM_12h_TC00283224_M12

description:
TP0001651A04_3_0.300000uM_PRF.DMEM_12h
TC00283224_M12

value: 12h exposure of 0.3 uM of Rotenone

value: Rotenone


title: TP0001651G03_6_10.000000uM_PRF.DMEM_12h_TC00283224_L23

description:
TP0001651G03_6_10.000000uM_PRF.DMEM_12h
TC00283224_L23

value: 12h exposure of 10 uM of Nilutamide

value: Nilutamide

value: 10 uM


title: TP0001651C06_1_0.030000uM_PRF.DMEM_12h_TC00283224_L19

description:
TP0001651C06_1_0.030000uM_PRF.DMEM_12h
TC00283224_L19

value: 12h exposure of 0.03 uM of Cycloheximide

value: Cycloheximide


title: TP0001651B01_3_0.300000uM_PRF.DMEM_12h_TC00283224_L18

description:
TP0001651B01_3_0.300000uM_PRF.DMEM_12h
TC00283224_L18

value: 12h exposure of 0.3 uM of Cyanazine

value: Cyanazine


title: GEN_PRF.DMEM_12h_TC00283224_L21

description:
GEN_PRF.DMEM_12h
TC00283224_L21

value: 6h exposure of 10 uM of Genistein

value: Genistein


title: TP0001651B02_6_10.000000uM_PRF.DMEM_12h_TC00283224_L17

description:
TP0001651B02_6_10.000000uM_PRF.DMEM_12h
TC00283224_L17

value: 12h exposure of 10 uM of 3,5,3'-Triiodothyronine


title: TP0001651A05_7_30.000000uM_PRF.DMEM_12h_TC00283224_L22

description:
TP0001651A05_7_30.000000uM_PRF.DMEM_12h
TC00283224_L22

value: 12h exposure of 30 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)

value: 30 uM


title: TP0001651A04_7_30.000000uM_PRF.DMEM_12h_TC00283224_L14

description:
TP0001651A04_7_30.000000uM_PRF.DMEM_12h
TC00283224_L14

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 30 uM of Rotenone


title: TP0001651E05_8_100.000000uM_PRF.DMEM_12h_TC00283224_L16

description:
TP0001651E05_8_100.000000uM_PRF.DMEM_12h
TC00283224_L16

value: 12h exposure of 100 uM of Atrazine

value: Atrazine


title: TP0001651A05_3_0.300000uM_PRF.DMEM_12h_TC00283224_L10

description:
TP0001651A05_3_0.300000uM_PRF.DMEM_12h
TC00283224_L10

value: 12h exposure of 0.3 uM of Clomiphene citrate (1:1)


title: TP0001651A01_7_30.000000uM_PRF.DMEM_12h_TC00283224_L11

description:
TP0001651A01_7_30.000000uM_PRF.DMEM_12h
TC00283224_L11

value: 12h exposure of 30 uM of Pyraclostrobin

value: Pyraclostrobin


title: TP0001651A03_1_0.030000uM_PRF.DMEM_12h_TC00283224_L13

description:
TP0001651A03_1_0.030000uM_PRF.DMEM_12h
TC00283224_L13

value: 12h exposure of 0.03 uM of Butafenacil

value: Butafenacil


title: DMSO_PRF.DMEM_12h_TC00283224_L15

description:
DMSO_PRF.DMEM_12h
TC00283224_L15

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651D05_1_0.030000uM_PRF.DMEM_12h_TC00283224_L07

description:
TP0001651D05_1_0.030000uM_PRF.DMEM_12h
TC00283224_L07

value: 12h exposure of 0.03 uM of Thiram

value: Thiram


title: TP0001651D05_7_30.000000uM_PRF.DMEM_12h_TC00283224_L05

description:
TP0001651D05_7_30.000000uM_PRF.DMEM_12h
TC00283224_L05

value: 12h exposure of 30 uM of Thiram


title: TP0001651A01_3_0.300000uM_PRF.DMEM_12h_TC00283224_L20

description:
TP0001651A01_3_0.300000uM_PRF.DMEM_12h
TC00283224_L20

value: 12h exposure of 0.3 uM of Pyraclostrobin


title: TP0001651A03_4_1.000000uM_PRF.DMEM_12h_TC00283224_L08

description:
TP0001651A03_4_1.000000uM_PRF.DMEM_12h
TC00283224_L08

value: 12h exposure of 1 uM of Butafenacil

value: 1 uM


title: TP0001651C06_2_0.100000uM_PRF.DMEM_12h_TC00283224_L06

description:
TP0001651C06_2_0.100000uM_PRF.DMEM_12h
TC00283224_L06

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.1 uM of Cycloheximide

value: Cycloheximide


title: TP0001651E03_2_0.100000uM_PRF.DMEM_12h_TC00283224_L09

description:
TP0001651E03_2_0.100000uM_PRF.DMEM_12h
TC00283224_L09

value: 12h exposure of 0.1 uM of Prochloraz

value: Prochloraz


title: TP0001651F01_5_3.000000uM_PRF.DMEM_12h_TC00283224_L04

description:
TP0001651F01_5_3.000000uM_PRF.DMEM_12h
TC00283224_L04

value: 12h exposure of 3 uM of Tetrac

value: Tetrac

value: 3 uM


title: TP0001651C02_3_0.300000uM_PRF.DMEM_12h_TC00283224_K22

description:
TP0001651C02_3_0.300000uM_PRF.DMEM_12h
TC00283224_K22

value: 12h exposure of 0.3 uM of 4-Hydroxytamoxifen


title: TP0001651G05_8_100.000000uM_PRF.DMEM_12h_TC00283224_K24

description:
TP0001651G05_8_100.000000uM_PRF.DMEM_12h
TC00283224_K24

value: 12h exposure of 100 uM of Cyproterone acetate

value: Cyproterone acetate


title: TP0001651D04_4_1.000000uM_PRF.DMEM_12h_TC00283224_K23

description:
TP0001651D04_4_1.000000uM_PRF.DMEM_12h
TC00283224_K23

value: 12h exposure of 1 uM of Clofibrate

value: Clofibrate


title: TP0001651D05_5_3.000000uM_PRF.DMEM_12h_TC00283224_L03

description:
TP0001651D05_5_3.000000uM_PRF.DMEM_12h
TC00283224_L03

value: 12h exposure of 3 uM of Thiram

value: Thiram


title: TP0001651B06_4_1.000000uM_PRF.DMEM_12h_TC00283224_K21

description:
TP0001651B06_4_1.000000uM_PRF.DMEM_12h
TC00283224_K21

value: 12h exposure of 1 uM of Troglitazone

value: Troglitazone


title: TP0001651C01_3_0.300000uM_PRF.DMEM_12h_TC00283224_K20

description:
TP0001651C01_3_0.300000uM_PRF.DMEM_12h
TC00283224_K20

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.3 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651A01_6_10.000000uM_PRF.DMEM_12h_TC00283224_L02

description:
TP0001651A01_6_10.000000uM_PRF.DMEM_12h
TC00283224_L02

value: 12h exposure of 10 uM of Pyraclostrobin

value: Pyraclostrobin

value: 10 uM


title: TP0001651D02_6_10.000000uM_PRF.DMEM_12h_TC00283224_K19

description:
TP0001651D02_6_10.000000uM_PRF.DMEM_12h
TC00283224_K19

value: 12h exposure of 10 uM of PFOA

value: PFOA


title: TP0001651G04_6_10.000000uM_PRF.DMEM_12h_TC00283224_K18

description:
TP0001651G04_6_10.000000uM_PRF.DMEM_12h
TC00283224_K18

value: 12h exposure of 10 uM of Cladribine

value: Cladribine


title: TP0001651H01_3_0.300000uM_PRF.DMEM_12h_TC00283224_K17

description:
TP0001651H01_3_0.300000uM_PRF.DMEM_12h
TC00283224_K17

value: 12h exposure of 0.3 uM of Flutamide

value: Flutamide


title: TP0001651H02_7_30.000000uM_PRF.DMEM_12h_TC00283224_K10

description:
TP0001651H02_7_30.000000uM_PRF.DMEM_12h
TC00283224_K10

value: 12h exposure of 30 uM of Maneb

value: Maneb

value: 30 uM


title: TP0001651B05_3_0.300000uM_PRF.DMEM_12h_TC00283224_J22

description:
TP0001651B05_3_0.300000uM_PRF.DMEM_12h
TC00283224_J22

value: 12h exposure of 0.3 uM of Amiodarone hydrochloride

value: Amiodarone hydrochloride


title: TP0001651D06_3_0.300000uM_PRF.DMEM_12h_TC00283224_K16

description:
TP0001651D06_3_0.300000uM_PRF.DMEM_12h
TC00283224_K16

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.3 uM of PFOS

value: PFOS


title: TP0001651H05_8_100.000000uM_PRF.DMEM_12h_TC00283224_K02

description:
TP0001651H05_8_100.000000uM_PRF.DMEM_12h
TC00283224_K02

value: 12h exposure of 100 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651C02_2_0.100000uM_PRF.DMEM_12h_TC00283224_K15

description:
TP0001651C02_2_0.100000uM_PRF.DMEM_12h
TC00283224_K15

value: 12h exposure of 0.1 uM of 4-Hydroxytamoxifen


title: TP0001651C06_4_1.000000uM_PRF.DMEM_12h_TC00283224_K13

description:
TP0001651C06_4_1.000000uM_PRF.DMEM_12h
TC00283224_K13

value: 12h exposure of 1 uM of Cycloheximide

value: Cycloheximide

value: 1 uM


title: TP0001651E05_7_30.000000uM_PRF.DMEM_12h_TC00283224_K03

description:
TP0001651E05_7_30.000000uM_PRF.DMEM_12h
TC00283224_K03

value: 12h exposure of 30 uM of Atrazine

value: Atrazine


title: TP0001651H04_5_3.000000uM_PRF.DMEM_12h_TC00283224_J21

description:
TP0001651H04_5_3.000000uM_PRF.DMEM_12h
TC00283224_J21

value: 12h exposure of 3 uM of Bisphenol A

value: Bisphenol A

value: 3 uM


title: TP0001651A04_6_10.000000uM_PRF.DMEM_12h_TC00283224_K11

description:
TP0001651A04_6_10.000000uM_PRF.DMEM_12h
TC00283224_K11

value: 12h exposure of 10 uM of Rotenone

value: Rotenone

value: 10 uM


title: TP0001651A05_2_0.100000uM_PRF.DMEM_12h_TC00283224_J23

description:
TP0001651A05_2_0.100000uM_PRF.DMEM_12h
TC00283224_J23

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.1 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: DMSO_PRF.DMEM_12h_TC00283224_K14

description:
DMSO_PRF.DMEM_12h
TC00283224_K14

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: TP0001651E05_1_0.030000uM_PRF.DMEM_12h_TC00283224_K12

description:
TP0001651E05_1_0.030000uM_PRF.DMEM_12h
TC00283224_K12

value: 12h exposure of 0.03 uM of Atrazine


title: TP0001651B03_3_0.300000uM_PRF.DMEM_12h_TC00283224_K06

description:
TP0001651B03_3_0.300000uM_PRF.DMEM_12h
TC00283224_K06

value: 12h exposure of 0.3 uM of Reserpine

value: Reserpine


title: TP0001651C06_7_30.000000uM_PRF.DMEM_12h_TC00283224_K09

description:
TP0001651C06_7_30.000000uM_PRF.DMEM_12h
TC00283224_K09

value: 12h exposure of 30 uM of Cycloheximide

value: Cycloheximide

value: 30 uM


title: TP0001651G01_6_10.000000uM_PRF.DMEM_12h_TC00283224_K04

description:
TP0001651G01_6_10.000000uM_PRF.DMEM_12h
TC00283224_K04

value: 12h exposure of 10 uM of Vinclozolin

value: Vinclozolin


title: TP0001651C04_4_1.000000uM_PRF.DMEM_12h_TC00283224_K05

description:
TP0001651C04_4_1.000000uM_PRF.DMEM_12h
TC00283224_K05

value: 12h exposure of 1 uM of Simvastatin

value: Simvastatin

value: 1 uM


title: TP0001651D03_1_0.030000uM_PRF.DMEM_12h_TC00283224_J20

description:
TP0001651D03_1_0.030000uM_PRF.DMEM_12h
TC00283224_J20

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.03 uM of Cypermethrin

value: Cypermethrin


title: TP0001651E04_5_3.000000uM_PRF.DMEM_12h_TC00283224_J18

description:
TP0001651E04_5_3.000000uM_PRF.DMEM_12h
TC00283224_J18

value: 12h exposure of 3 uM of Farglitazar

value: Farglitazar

value: 3 uM


title: TP0001651A02_6_10.000000uM_PRF.DMEM_12h_TC00283224_J17

description:
TP0001651A02_6_10.000000uM_PRF.DMEM_12h
TC00283224_J17

value: 12h exposure of 10 uM of Imazalil

value: Imazalil

value: 10 uM


title: TP0001651B03_2_0.100000uM_PRF.DMEM_12h_TC00283224_J19

description:
TP0001651B03_2_0.100000uM_PRF.DMEM_12h
TC00283224_J19

value: 12h exposure of 0.1 uM of Reserpine

value: Reserpine


title: TP0001651H03_8_100.000000uM_PRF.DMEM_12h_TC00283224_J16

description:
TP0001651H03_8_100.000000uM_PRF.DMEM_12h
TC00283224_J16

value: 12h exposure of 100 uM of Fomesafen

value: Fomesafen


title: TP0001651D04_5_3.000000uM_PRF.DMEM_12h_TC00283224_K08

description:
TP0001651D04_5_3.000000uM_PRF.DMEM_12h
TC00283224_K08

value: 12h exposure of 3 uM of Clofibrate

value: Clofibrate


title: TP0001651A06_7_30.000000uM_PRF.DMEM_12h_TC00283224_K07

description:
TP0001651A06_7_30.000000uM_PRF.DMEM_12h
TC00283224_K07

value: 12h exposure of 30 uM of Cyproconazole

value: Cyproconazole

value: 30 uM


title: TP0001651B03_8_100.000000uM_PRF.DMEM_12h_TC00283224_J13

description:
TP0001651B03_8_100.000000uM_PRF.DMEM_12h
TC00283224_J13

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 100 uM of Reserpine


title: TP0001651C01_5_3.000000uM_PRF.DMEM_12h_TC00283224_J12

description:
TP0001651C01_5_3.000000uM_PRF.DMEM_12h
TC00283224_J12

value: 12h exposure of 3 uM of Fenpyroximate (Z,E)

value: Fenpyroximate (Z,E)


title: TP0001651F05_1_0.030000uM_PRF.DMEM_12h_TC00283224_J14

description:
TP0001651F05_1_0.030000uM_PRF.DMEM_12h
TC00283224_J14

value: 12h exposure of 0.03 uM of Fenofibrate

value: Fenofibrate


title: TP0001651B03_6_10.000000uM_PRF.DMEM_12h_TC00283224_J11

description:
TP0001651B03_6_10.000000uM_PRF.DMEM_12h
TC00283224_J11

value: 12h exposure of 10 uM of Reserpine


title: TP0001651C04_6_10.000000uM_PRF.DMEM_12h_TC00283224_J15

description:
TP0001651C04_6_10.000000uM_PRF.DMEM_12h
TC00283224_J15

value: 12h exposure of 10 uM of Simvastatin

value: Simvastatin

value: 10 uM


title: TP0001651D03_8_100.000000uM_PRF.DMEM_12h_TC00283224_J24

description:
TP0001651D03_8_100.000000uM_PRF.DMEM_12h
TC00283224_J24

value: 12h exposure of 100 uM of Cypermethrin

value: Cypermethrin


title: TP0001651D01_8_100.000000uM_PRF.DMEM_12h_TC00283224_L12

description:
TP0001651D01_8_100.000000uM_PRF.DMEM_12h
TC00283224_L12

value: 12h exposure of 100 uM of Lactofen

value: Lactofen


title: TP0001651C03_8_100.000000uM_PRF.DMEM_12h_TC00283224_J09

description:
TP0001651C03_8_100.000000uM_PRF.DMEM_12h
TC00283224_J09

value: 12h exposure of 100 uM of Simazine

value: Simazine


title: TP0001651D05_4_1.000000uM_PRF.DMEM_12h_TC00283224_J10

description:
TP0001651D05_4_1.000000uM_PRF.DMEM_12h
TC00283224_J10

value: 12h exposure of 1 uM of Thiram

value: Thiram

value: 1 uM


title: TP0001651C03_1_0.030000uM_PRF.DMEM_12h_TC00283224_J07

description:
TP0001651C03_1_0.030000uM_PRF.DMEM_12h
TC00283224_J07

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.03 uM of Simazine


title: TP0001651C06_8_100.000000uM_PRF.DMEM_12h_TC00283224_J05

description:
TP0001651C06_8_100.000000uM_PRF.DMEM_12h
TC00283224_J05

value: 12h exposure of 100 uM of Cycloheximide

value: Cycloheximide


title: TP0001651H05_6_10.000000uM_PRF.DMEM_12h_TC00283224_I23

description:
TP0001651H05_6_10.000000uM_PRF.DMEM_12h
TC00283224_I23

value: 12h exposure of 10 uM of Trifloxystrobin

value: Trifloxystrobin


title: TP0001651H05_3_0.300000uM_PRF.DMEM_12h_TC00283224_I22

description:
TP0001651H05_3_0.300000uM_PRF.DMEM_12h
TC00283224_I22

value: 12h exposure of 0.3 uM of Trifloxystrobin


title: TP0001651C05_8_100.000000uM_PRF.DMEM_12h_TC00283224_J08

description:
TP0001651C05_8_100.000000uM_PRF.DMEM_12h
TC00283224_J08

value: 12h exposure of 100 uM of Bisphenol B

value: Bisphenol B


title: TP0001651F02_5_3.000000uM_PRF.DMEM_12h_TC00283224_J06

description:
TP0001651F02_5_3.000000uM_PRF.DMEM_12h
TC00283224_J06

value: 12h exposure of 3 uM of Ziram

value: Ziram

value: 3 uM


title: TP0001651F04_6_10.000000uM_PRF.DMEM_12h_TC00283224_I15

description:
TP0001651F04_6_10.000000uM_PRF.DMEM_12h
TC00283224_I15

value: 12h exposure of 10 uM of Fulvestrant

value: Fulvestrant

value: 10 uM


title: Lysis Buffer_TC00283224_J01

description:
Lysis Buffer
TC00283224_J01

source_name: Lysis Buffer

value: untreated


title: TP0001651G02_7_30.000000uM_PRF.DMEM_12h_TC00283224_I24

description:
TP0001651G02_7_30.000000uM_PRF.DMEM_12h
TC00283224_I24

value: 12h exposure of 30 uM of Lovastatin

value: Lovastatin

value: 30 uM


title: TP0001651E01_2_0.100000uM_PRF.DMEM_12h_TC00283224_J02

description:
TP0001651E01_2_0.100000uM_PRF.DMEM_12h
TC00283224_J02

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 0.1 uM of Bifenthrin

value: Bifenthrin


title: TP0001651G01_5_3.000000uM_PRF.DMEM_12h_TC00283224_I21

description:
TP0001651G01_5_3.000000uM_PRF.DMEM_12h
TC00283224_I21

value: 12h exposure of 3 uM of Vinclozolin

value: Vinclozolin


title: TP0001651C02_5_3.000000uM_PRF.DMEM_12h_TC00283224_J04

description:
TP0001651C02_5_3.000000uM_PRF.DMEM_12h
TC00283224_J04

value: 12h exposure of 3 uM of 4-Hydroxytamoxifen


title: TP0001651G02_5_3.000000uM_PRF.DMEM_12h_TC00283224_J03

description:
TP0001651G02_5_3.000000uM_PRF.DMEM_12h
TC00283224_J03

value: 12h exposure of 3 uM of Lovastatin


title: TP0001651E03_3_0.300000uM_PRF.DMEM_12h_TC00283224_I10

description:
TP0001651E03_3_0.300000uM_PRF.DMEM_12h
TC00283224_I10

value: 12h exposure of 0.3 uM of Prochloraz

value: Prochloraz


title: TP0001651E01_3_0.300000uM_PRF.DMEM_12h_TC00283224_I14

description:
TP0001651E01_3_0.300000uM_PRF.DMEM_12h
TC00283224_I14

value: 12h exposure of 0.3 uM of Bifenthrin


title: TP0001651B04_6_10.000000uM_PRF.DMEM_12h_TC00283224_I12

description:
TP0001651B04_6_10.000000uM_PRF.DMEM_12h
TC00283224_I12

value: 12h exposure of 10 uM of Propiconazole

value: Propiconazole


title: TP0001651E03_6_10.000000uM_PRF.DMEM_12h_TC00283224_I11

description:
TP0001651E03_6_10.000000uM_PRF.DMEM_12h
TC00283224_I11

value: 12h exposure of 10 uM of Prochloraz

value: 10 uM


title: TP0001651F02_6_10.000000uM_PRF.DMEM_12h_TC00283224_I13

description:
TP0001651F02_6_10.000000uM_PRF.DMEM_12h
TC00283224_I13

value: 12h exposure of 10 uM of Ziram

value: Ziram


title: TP0001651E03_7_30.000000uM_PRF.DMEM_12h_TC00283224_I20

description:
TP0001651E03_7_30.000000uM_PRF.DMEM_12h
TC00283224_I20

value: 12h exposure of 30 uM of Prochloraz

value: 30 uM


title: TP0001651A05_8_100.000000uM_PRF.DMEM_12h_TC00283224_I18

description:
TP0001651A05_8_100.000000uM_PRF.DMEM_12h
TC00283224_I18

value: DMEM + 10% charcoal-stripped FBS

value: 12h exposure of 100 uM of Clomiphene citrate (1:1)

value: Clomiphene citrate (1:1)


title: TP0001651H04_1_0.030000uM_PRF.DMEM_12h_TC00283224_I19

description:
TP0001651H04_1_0.030000uM_PRF.DMEM_12h
TC00283224_I19

value: 12h exposure of 0.03 uM of Bisphenol A

value: Bisphenol A


title: TP0001651H03_4_1.000000uM_PRF.DMEM_12h_TC00283224_I17

description:
TP0001651H03_4_1.000000uM_PRF.DMEM_12h
TC00283224_I17

value: 12h exposure of 1 uM of Fomesafen

value: Fomesafen

value: 1 uM


title: TP0001651E04_7_30.000000uM_PRF.DMEM_12h_TC00283224_I08

description:
TP0001651E04_7_30.000000uM_PRF.DMEM_12h
TC00283224_I08

value: 12h exposure of 30 uM of Farglitazar

value: Farglitazar


title: TP0001651G02_8_100.000000uM_PRF.DMEM_12h_TC00283224_I09

description:
TP0001651G02_8_100.000000uM_PRF.DMEM_12h
TC00283224_I09

value: 12h exposure of 100 uM of Lovastatin

value: Lovastatin


title: TP0001651G04_7_30.000000uM_PRF.DMEM_12h_TC00283224_I07

description:
TP0001651G04_7_30.000000uM_PRF.DMEM_12h
TC00283224_I07

value: 12h exposure of 30 uM of Cladribine

value: Cladribine