title: Female Heart, 0.3 mg/kg/day MOPA, Animal 182

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_182h

value: Heart


title: Female Heart, 0.1 mg/kg/day MOPA, Animal 176

status: Public on Mar 05 2024

type: SRA

city: RTP

first: Logan

middle: J

last: Everett

state: North Carolina

address: 109 T.W. Alexander Dr

department: Office of Research and Development

country: USA

institute: U.S. Environmental Protection Agency

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_176h

library_source: transcriptomic

data_processing:
Raw sequencing reads (FASTQ files) were aligned to known probe sequences listed in the TempO-Seq probe manifest using HISAT2 to compute a matrix of read counts for each probe in each sample.
Assembly: TempO-seq Rat S1500+ v1.2
Supplementary files format and content: Count table CSV files contain a row for each known probe and a column for each sample. Each cell contains the number of reads from a single cell uniquely aligned to a single probe sequence
Supplementary files format and content: Probe manifest CSV file contains a row for each known probe with the probe name, sequence, and target gene

molecule: total RNA

organism: Rattus norvegicus

source_name: Heart

growth_protocol: Male and female Sprague Dawley (Crl:CD IGS, Charles River Laboratory) rats are purchased at 6 – 8 weeks of age. Upon receipt, the animals are placed on a standard, purified laboratory diet and reverse osmosis treated drinking water ad libitum. The specific brand and type of food and source of the water should be noted in Appendix II (Detailed Animal Study Report) of the individual assessment. After a 7- to 14-day quarantine and acclimation period, the animals are weighed and randomly assigned by weight to chemical exposure and control groups. Only clinically healthy animals are used in the study. The target age for initiating exposure is 8 - 10 weeks.

extract_protocol:
Treated and control animals are necropsied approximately 24 hours after the last exposure. Carbon dioxide asphyxiation is used as the method of euthanasia, with death confirmed by a secondary method such as exsanguination or cervical dislocation. The following tissues were dissected from each animal: kidney, liver, adrenal gland, brain, heart, lung, ovary (females), spleen, testis (males), thyroid, thymus, and uterus (females). Tissue samples were collected within ten minutes of termination. The left liver lobe, right kidney, left lung, both testis, uterus, heart, spleen, thymus and whole brain were sectioned into 5mm^3 pieces. Samples from these larger tissues were then individually divided into at least 3 cryovials. At least two of the samples from each tissue in each animal were preserved in RNAlater™ (Thermo Fisher Scientific) at 4°C overnight and then frozen at approximately -20°C for up to 3 weeks before transferring to approximately -80°C. At least one sample from each larger tissue is frozen immediately in liquid nitrogen and stored at approximately -80°C.   The smaller bilateral tissues: adrenal glands, thyroid gland, and ovaries (female) are placed into two cryovials and preserved in RNALater with the left side of the tissue or gland going into the first cryovial and the right side going into the second cryovial. The first tube of RNALater preserved tissue is submitted for sequencing. For each tissue undergoing transcriptomic analysis, total RNA is extracted from one of the aliquots stored in RNAlater™.
The isolated total RNA is used to perform targeted RNA sequencing (RNA-seq) using the BioSpyder TempO-Seq rat S1500+ assay (v1.2) according to manufacturer’s instructions. No specific RNA purity or integrity criteria are applied to the RNA samples as the TempO-Seq assay has been designed to provide high quality gene expression measurements on whole cell lysates, purified RNA, and formalin-fixed paraffin embedded tissue.

treatment_protocol: For oral gavage studies, at least four male and four female rats per dose group receive the vehicle alone or test article in vehicle via gavage (5 or 10 ml/kg) for five days. Animals are weighed daily prior to administration and are observed twice daily, once during administration and once in the late afternoon, at least six hours apart, for assessment of moribundity and mortality. Formal clinical observations are performed on the first day post-dosing and prior to necropsy. Moribund animals or animals exhibiting overt clinical toxicity are removed from the study. The temperature in the experimental animal room is maintained at a target of 22°C (± 3°C) with a relative humidity that is ideally between 50-60% but is at least 30% and preferably not to exceed 70% other than during room cleaning. Lighting is artificial with a sequence of 12 hours light, 12 hours dark. Animals are housed individually or caged in small groups of no more than three animals of the same sex in accordance with local institutional animal care and use requirements.

tag: Sex

value: Female

tag: tissue

tag: strain

value: Sprague Dawley

tag: age

value: 10-12 weeks post acclimation

tag: treatment

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage

tag: sample qc_issue

value: No Issue


title: Female Heart, 0.01 mg/kg/day MOPA, Animal 171

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_171h

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Female Heart, 0.1 mg/kg/day MOPA, Animal 174

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_174h


title: Female Heart, Vehicle Control, Animal 167

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_167h

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Heart, 0.01 mg/kg/day MOPA, Animal 170

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_170h


title: Female Heart, 0.01 mg/kg/day MOPA, Animal 169

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_169h


title: Female Heart, 0.01 mg/kg/day MOPA, Animal 168

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_168h


title: Female Heart, Vehicle Control, Animal 165

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_165h


title: Female Heart, Vehicle Control, Animal 166

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_166h


title: Female Heart, Vehicle Control, Animal 161

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_161h


title: Female Heart, Vehicle Control, Animal 160

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_160h


title: Female Heart, Vehicle Control, Animal 163

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_163h


title: Female Heart, Vehicle Control, Animal 164

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_164h


title: Male Heart, 300 mg/kg/day MOPA, Animal 158

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_158h

value: Male

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Female Heart, 0.1 mg/kg/day MOPA, Animal 175

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_175h

value: Female

value: Heart

value: Sprague Dawley

value: 10-12 weeks post acclimation


title: Female Heart, Vehicle Control, Animal 162

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_162h

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Heart, 300 mg/kg/day MOPA, Animal 157

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_157h

value: route of_exposure:Oral gavage


title: Male Heart, 100 mg/kg/day MOPA, Animal 152

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_152h

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: No Issue


title: Male Heart, 300 mg/kg/day MOPA, Animal 155

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_155h


title: Male Heart, 100 mg/kg/day MOPA, Animal 153

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_153h


title: Male Heart, 300 mg/kg/day MOPA, Animal 159

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_159h


title: Male Heart, 300 mg/kg/day MOPA, Animal 156

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_156h


title: Male Heart, 100 mg/kg/day MOPA, Animal 151

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_151h


title: Female Heart, 0.01 mg/kg/day MOPA, Animal 172

description:
etap_mopa_heart_female_counts.csv
Plate_31_MOPA_heartf_172h

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Male Heart, 100 mg/kg/day MOPA, Animal 150

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_150h

value: Male


title: Male Heart, 30 mg/kg/day MOPA, Animal 145

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_145h

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Male Heart, 30 mg/kg/day MOPA, Animal 149

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_149h


title: Male Heart, 30 mg/kg/day MOPA, Animal 146

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_146h


title: Male Heart, 10 mg/kg/day MOPA, Animal 143

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_143h

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Male Heart, 30 mg/kg/day MOPA, Animal 147

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_147h

value: Heart

value: Sprague Dawley

value: 10-12 weeks post acclimation


title: Male Heart, 10 mg/kg/day MOPA, Animal 142

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_142h

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Male Heart, 10 mg/kg/day MOPA, Animal 140

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_140h


title: Male Heart, 3 mg/kg/day MOPA, Animal 139

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_139h

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: Male Heart, 3 mg/kg/day MOPA, Animal 138

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_138h

value: No Issue


title: Male Heart, 3 mg/kg/day MOPA, Animal 136

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_136h


title: Male Heart, 3 mg/kg/day MOPA, Animal 137

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_137h


title: Male Heart, 100 mg/kg/day MOPA, Animal 154

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_154h

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Male Heart, 1 mg/kg/day MOPA, Animal 133

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_133h

value: Male

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Male Heart, 10 mg/kg/day MOPA, Animal 141

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_141h

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Male Heart, 3 mg/kg/day MOPA, Animal 135

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_135h

value: Heart

value: Sprague Dawley

value: 10-12 weeks post acclimation


title: Male Heart, 1 mg/kg/day MOPA, Animal 131

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_131h

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Male Heart, 0.3 mg/kg/day MOPA, Animal 127

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_127h

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Male Heart, 0.3 mg/kg/day MOPA, Animal 125

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_125h

value: No Issue


title: Male Heart, 10 mg/kg/day MOPA, Animal 144

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_144h


title: Male Heart, 0.1 mg/kg/day MOPA, Animal 123

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_123h

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: < 50% reads aligned


title: Male Heart, 0.3 mg/kg/day MOPA, Animal 126

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_126h

value: Male


title: Male Heart, 1 mg/kg/day MOPA, Animal 130

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_130h

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Male Heart, 0.1 mg/kg/day MOPA, Animal 122

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_122h

value: Heart


title: Male Heart, 1 mg/kg/day MOPA, Animal 132

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_132h

value: Sprague Dawley


title: Male Heart, 0.1 mg/kg/day MOPA, Animal 120

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_120h

value: 10-12 weeks post acclimation


title: Male Heart, 0.01 mg/kg/day MOPA, Animal 119

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_119h

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Heart, 0.01 mg/kg/day MOPA, Animal 118

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_118h

value: route of_exposure:Oral gavage


title: Male Heart, 0.01 mg/kg/day MOPA, Animal 117

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_117h

value: No Issue


title: Male Heart, 0.01 mg/kg/day MOPA, Animal 116

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_116h


title: Male Heart, 0.1 mg/kg/day MOPA, Animal 121

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_121h

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage


title: Male Heart, 1 mg/kg/day MOPA, Animal 134

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_134h


title: Male Heart, Vehicle Control, Animal 113

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_113h

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Heart, 0.01 mg/kg/day MOPA, Animal 115

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_115h

value: Male


title: Male Heart, Vehicle Control, Animal 111

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_111h


title: Male Heart, Vehicle Control, Animal 109

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_109h


title: Male Heart, Vehicle Control, Animal 112

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_112h


title: Male Heart, Vehicle Control, Animal 110

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_110h


title: Male Heart, Vehicle Control, Animal 114

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_114h


title: Male Heart, 0.3 mg/kg/day MOPA, Animal 128

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_128h

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Male Heart, 0.3 mg/kg/day MOPA, Animal 129

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_129h

value: Heart


title: Male Heart, Vehicle Control, Animal 107

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_107h

value: Sprague Dawley


title: Female Thyroid, 300 mg/kg/day MOPA, Animal 211

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_211r

source_name: Thyroid

value: Female

value: Thyroid

value: 10-12 weeks post acclimation

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Male Heart, Vehicle Control, Animal 108

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_108h

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage

value: No Issue


title: Male Heart, 0.1 mg/kg/day MOPA, Animal 124

description:
etap_mopa_heart_male_counts.csv
Plate_30_MOPA_heartm_124h

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: Female Thyroid, 300 mg/kg/day MOPA, Animal 210

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_210r


title: Female Thyroid, 100 mg/kg/day MOPA, Animal 207

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_207r

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Female Thyroid, 300 mg/kg/day MOPA, Animal 209

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_209r


title: Female Thyroid, 100 mg/kg/day MOPA, Animal 206

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_206r


title: Female Thyroid, 100 mg/kg/day MOPA, Animal 205

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_205r


title: Female Thyroid, 100 mg/kg/day MOPA, Animal 204

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_204r


title: Female Thyroid, 100 mg/kg/day MOPA, Animal 203

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_203r


title: Female Thyroid, 10 mg/kg/day MOPA, Animal 195

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_195r

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Female Thyroid, 30 mg/kg/day MOPA, Animal 201

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_201r

value: Female

value: Thyroid

value: Sprague Dawley

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Female Thyroid, 30 mg/kg/day MOPA, Animal 202

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_202r

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Female Thyroid, 30 mg/kg/day MOPA, Animal 198

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_198r

value: No Issue


title: Female Thyroid, 30 mg/kg/day MOPA, Animal 200

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_200r


title: Female Thyroid, 30 mg/kg/day MOPA, Animal 199

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_199r


title: Female Thyroid, 10 mg/kg/day MOPA, Animal 197

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_197r


title: Female Thyroid, 3 mg/kg/day MOPA, Animal 192

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_192r

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: Female Thyroid, 10 mg/kg/day MOPA, Animal 193

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_193r


title: Female Thyroid, 10 mg/kg/day MOPA, Animal 194

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_194r


title: Female Thyroid, 3 mg/kg/day MOPA, Animal 191

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_191r


title: Female Thyroid, 3 mg/kg/day MOPA, Animal 190

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_190r


title: Female Thyroid, 3 mg/kg/day MOPA, Animal 188

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_188r


title: Female Thyroid, 3 mg/kg/day MOPA, Animal 189

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_189r


title: Female Thyroid, 1 mg/kg/day MOPA, Animal 187

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_187r

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Female Thyroid, 1 mg/kg/day MOPA, Animal 186

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_186r


title: Female Thyroid, 1 mg/kg/day MOPA, Animal 185

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_185r


title: Female Thyroid, 1 mg/kg/day MOPA, Animal 184

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_184r


title: Female Thyroid, 0.3 mg/kg/day MOPA, Animal 181

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_181r

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Female Thyroid, 300 mg/kg/day MOPA, Animal 208

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_208r

value: Female

value: Thyroid

value: Sprague Dawley

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Female Thyroid, 1 mg/kg/day MOPA, Animal 183

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_183r

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Female Thyroid, 0.3 mg/kg/day MOPA, Animal 182

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_182r

value: No Issue


title: Female Thyroid, 0.3 mg/kg/day MOPA, Animal 180

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_180r


title: Female Thyroid, 0.3 mg/kg/day MOPA, Animal 178

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_178r


title: Female Thyroid, 0.3 mg/kg/day MOPA, Animal 179

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_179r


title: Female Thyroid, 0.1 mg/kg/day MOPA, Animal 177

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_177r

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: Female Thyroid, 10 mg/kg/day MOPA, Animal 196

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_196r

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Female Thyroid, 0.1 mg/kg/day MOPA, Animal 176

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_176r


title: Female Thyroid, 0.1 mg/kg/day MOPA, Animal 175

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_175r


title: Female Thyroid, 0.1 mg/kg/day MOPA, Animal 174

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_174r


title: Female Thyroid, 0.01 mg/kg/day MOPA, Animal 171

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_171r

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Female Thyroid, 0.1 mg/kg/day MOPA, Animal 173

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_173r

value: Female

value: Thyroid

value: Sprague Dawley


title: Female Thyroid, Vehicle Control, Animal 167

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_167r

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Thyroid, 0.01 mg/kg/day MOPA, Animal 170

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_170r

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Female Thyroid, 0.01 mg/kg/day MOPA, Animal 169

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_169r

value: No Issue


title: Female Thyroid, 0.01 mg/kg/day MOPA, Animal 168

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_168r


title: Female Thyroid, Vehicle Control, Animal 165

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_165r


title: Female Thyroid, 0.01 mg/kg/day MOPA, Animal 172

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_172r


title: Female Thyroid, Vehicle Control, Animal 161

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_161r


title: Female Thyroid, Vehicle Control, Animal 164

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_164r


title: Female Thyroid, Vehicle Control, Animal 163

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_163r


title: Male Thyroid, 100 mg/kg/day MOPA, Animal 154

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_154r

value: Male

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Male Thyroid, 300 mg/kg/day MOPA, Animal 156

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_156r

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Male Thyroid, 300 mg/kg/day MOPA, Animal 157

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_157r


title: Male Thyroid, 300 mg/kg/day MOPA, Animal 155

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_155r


title: Female Thyroid, Vehicle Control, Animal 160

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_160r

value: Female


title: Male Thyroid, 100 mg/kg/day MOPA, Animal 153

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_153r

value: Thyroid


title: Male Thyroid, 300 mg/kg/day MOPA, Animal 158

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_158r

value: Sprague Dawley


title: Male Thyroid, 100 mg/kg/day MOPA, Animal 151

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_151r


title: Male Thyroid, 300 mg/kg/day MOPA, Animal 159

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_159r


title: Male Thyroid, 100 mg/kg/day MOPA, Animal 150

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_150r


title: Male Thyroid, 30 mg/kg/day MOPA, Animal 149

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_149r

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Male Thyroid, 100 mg/kg/day MOPA, Animal 152

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_152r

value: 10-12 weeks post acclimation


title: Male Thyroid, 30 mg/kg/day MOPA, Animal 146

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_146r

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Thyroid, 30 mg/kg/day MOPA, Animal 147

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_147r

value: route of_exposure:Oral gavage


title: Male Thyroid, 30 mg/kg/day MOPA, Animal 145

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_145r

value: No Issue


title: Male Thyroid, 10 mg/kg/day MOPA, Animal 144

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_144r

value: Male

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Male Thyroid, 10 mg/kg/day MOPA, Animal 143

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_143r


title: Female Thyroid, Vehicle Control, Animal 166

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_166r

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Thyroid, Vehicle Control, Animal 162

description:
etap_mopa_thyroid_female_counts.csv
Plate_29_MOPA_thyrof_162r

value: Female

value: Outlier sample removed


title: Male Thyroid, 10 mg/kg/day MOPA, Animal 141

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_141r

value: Thyroid

value: Sprague Dawley


title: Male Thyroid, 10 mg/kg/day MOPA, Animal 142

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_142r


title: Male Thyroid, 10 mg/kg/day MOPA, Animal 140

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_140r


title: Male Thyroid, 3 mg/kg/day MOPA, Animal 138

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_138r

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: Male Thyroid, 3 mg/kg/day MOPA, Animal 139

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_139r

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Thyroid, 3 mg/kg/day MOPA, Animal 135

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_135r

value: route of_exposure:Oral gavage

value: No Issue


title: Male Thyroid, 3 mg/kg/day MOPA, Animal 136

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_136r

value: Male


title: Male Thyroid, 3 mg/kg/day MOPA, Animal 137

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_137r


title: Male Thyroid, 1 mg/kg/day MOPA, Animal 134

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_134r

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Male Thyroid, 1 mg/kg/day MOPA, Animal 133

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_133r


title: Male Thyroid, 1 mg/kg/day MOPA, Animal 131

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_131r


title: Male Thyroid, 0.3 mg/kg/day MOPA, Animal 129

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_129r

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Male Thyroid, 0.3 mg/kg/day MOPA, Animal 126

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_126r


title: Male Thyroid, 1 mg/kg/day MOPA, Animal 132

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_132r


title: Male Thyroid, 0.3 mg/kg/day MOPA, Animal 127

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_127r


title: Male Thyroid, 0.1 mg/kg/day MOPA, Animal 122

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_122r

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: Male Thyroid, 0.3 mg/kg/day MOPA, Animal 125

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_125r

value: Thyroid

value: Sprague Dawley


title: Male Thyroid, 0.1 mg/kg/day MOPA, Animal 124

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_124r


title: Male Thyroid, 0.3 mg/kg/day MOPA, Animal 128

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_128r


title: Male Thyroid, 0.1 mg/kg/day MOPA, Animal 121

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_121r


title: Male Thyroid, 0.1 mg/kg/day MOPA, Animal 120

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_120r


title: Male Thyroid, 0.01 mg/kg/day MOPA, Animal 117

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_117r

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Male Thyroid, 0.01 mg/kg/day MOPA, Animal 115

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_115r

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Male Thyroid, Vehicle Control, Animal 114

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_114r

value: Male

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: No Issue


title: Male Thyroid, 0.01 mg/kg/day MOPA, Animal 116

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_116r


title: Male Thyroid, 0.01 mg/kg/day MOPA, Animal 118

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_118r


title: Male Thyroid, Vehicle Control, Animal 113

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_113r


title: Male Thyroid, Vehicle Control, Animal 111

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_111r


title: Male Thyroid, Vehicle Control, Animal 110

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_110r


title: Male Thyroid, Vehicle Control, Animal 112

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_112r


title: Male Thyroid, Vehicle Control, Animal 108

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_108r


title: Male Thyroid, Vehicle Control, Animal 107

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_107r


title: Female Spleen, 300 mg/kg/day MOPA, Animal 211

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_211s

source_name: Spleen

value: Female

value: Spleen

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Female Spleen, 300 mg/kg/day MOPA, Animal 209

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_209s

value: Sprague Dawley


title: Male Thyroid, 0.01 mg/kg/day MOPA, Animal 119

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_119r

value: Thyroid

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage


title: Female Spleen, 300 mg/kg/day MOPA, Animal 208

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_208s


title: Male Thyroid, 1 mg/kg/day MOPA, Animal 130

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_130r

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Male Thyroid, 0.1 mg/kg/day MOPA, Animal 123

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_123r

value: 10-12 weeks post acclimation

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Female Spleen, 100 mg/kg/day MOPA, Animal 205

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_205s

value: Female

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: No Issue


title: Female Spleen, 100 mg/kg/day MOPA, Animal 207

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_207s

value: Spleen

value: Sprague Dawley


title: Female Spleen, 100 mg/kg/day MOPA, Animal 206

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_206s


title: Female Spleen, 100 mg/kg/day MOPA, Animal 204

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_204s


title: Female Spleen, 30 mg/kg/day MOPA, Animal 201

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_201s

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Female Spleen, 100 mg/kg/day MOPA, Animal 203

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_203s


title: Female Spleen, 30 mg/kg/day MOPA, Animal 200

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_200s


title: Female Spleen, 30 mg/kg/day MOPA, Animal 202

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_202s


title: Female Spleen, 30 mg/kg/day MOPA, Animal 199

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_199s


title: Female Spleen, 10 mg/kg/day MOPA, Animal 197

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_197s

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Female Spleen, 30 mg/kg/day MOPA, Animal 198

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_198s

value: 10-12 weeks post acclimation


title: Female Spleen, 10 mg/kg/day MOPA, Animal 196

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_196s


title: Female Spleen, 10 mg/kg/day MOPA, Animal 195

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_195s


title: Female Spleen, 10 mg/kg/day MOPA, Animal 194

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_194s


title: Male Thyroid, Vehicle Control, Animal 109

description:
etap_mopa_thyroid_male_counts.csv
Plate_28_MOPA_thyrom_109r

value: Male

value: Thyroid

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Spleen, 300 mg/kg/day MOPA, Animal 210

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_210s

value: Female

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage

value: Outlier sample removed


title: Female Spleen, 3 mg/kg/day MOPA, Animal 191

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_191s

value: Spleen

value: Sprague Dawley

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5

value: No Issue


title: Female Spleen, 3 mg/kg/day MOPA, Animal 189

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_189s

value: 10-12 weeks post acclimation


title: Female Spleen, 1 mg/kg/day MOPA, Animal 186

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_186s

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Female Spleen, 3 mg/kg/day MOPA, Animal 188

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_188s

value: Female


title: Female Spleen, 1 mg/kg/day MOPA, Animal 187

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_187s


title: Female Spleen, 3 mg/kg/day MOPA, Animal 190

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_190s


title: Female Spleen, 3 mg/kg/day MOPA, Animal 192

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_192s


title: Female Spleen, 1 mg/kg/day MOPA, Animal 185

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_185s


title: Female Spleen, 0.3 mg/kg/day MOPA, Animal 182

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_182s

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Female Spleen, 1 mg/kg/day MOPA, Animal 184

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_184s

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Spleen, 1 mg/kg/day MOPA, Animal 183

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_183s

value: route of_exposure:Oral gavage


title: Female Spleen, 0.3 mg/kg/day MOPA, Animal 181

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_181s


title: Female Spleen, 0.3 mg/kg/day MOPA, Animal 180

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_180s


title: Female Spleen, 0.1 mg/kg/day MOPA, Animal 177

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_177s

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: Female Spleen, 0.3 mg/kg/day MOPA, Animal 178

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_178s

value: Spleen

value: Sprague Dawley


title: Female Spleen, 0.3 mg/kg/day MOPA, Animal 179

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_179s


title: Female Spleen, 0.1 mg/kg/day MOPA, Animal 175

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_175s


title: Female Spleen, 0.1 mg/kg/day MOPA, Animal 174

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_174s


title: Female Spleen, 0.01 mg/kg/day MOPA, Animal 172

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_172s

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Female Spleen, 0.1 mg/kg/day MOPA, Animal 173

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_173s

value: 10-12 weeks post acclimation

value: No Issue


title: Female Spleen, 0.1 mg/kg/day MOPA, Animal 176

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_176s


title: Female Spleen, 0.01 mg/kg/day MOPA, Animal 171

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_171s


title: Female Spleen, 0.01 mg/kg/day MOPA, Animal 170

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_170s


title: Female Spleen, 0.01 mg/kg/day MOPA, Animal 169

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_169s


title: Female Spleen, Vehicle Control, Animal 167

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_167s

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Spleen, Vehicle Control, Animal 166

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_166s

value: Female


title: Female Spleen, Vehicle Control, Animal 165

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_165s


title: Female Spleen, 10 mg/kg/day MOPA, Animal 193

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_193s

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Female Spleen, Vehicle Control, Animal 164

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_164s

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Female Spleen, Vehicle Control, Animal 163

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_163s


title: Female Spleen, Vehicle Control, Animal 161

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_161s


title: Female Spleen, Vehicle Control, Animal 162

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_162s


title: Male Spleen, 300 mg/kg/day MOPA, Animal 159

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_159s

value: Male

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Male Spleen, 300 mg/kg/day MOPA, Animal 158

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_158s

value: Spleen

value: Sprague Dawley


title: Female Spleen, Vehicle Control, Animal 160

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_160s

value: 10-12 weeks post acclimation


title: Male Spleen, 300 mg/kg/day MOPA, Animal 157

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_157s

value: No Issue


title: Male Spleen, 300 mg/kg/day MOPA, Animal 156

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_156s


title: Male Spleen, 300 mg/kg/day MOPA, Animal 155

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_155s


title: Male Spleen, 100 mg/kg/day MOPA, Animal 153

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_153s

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Male Spleen, 100 mg/kg/day MOPA, Animal 150

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_150s

value: < 50% reads aligned


title: Male Spleen, 30 mg/kg/day MOPA, Animal 146

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_146s

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Male Spleen, 100 mg/kg/day MOPA, Animal 152

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_152s

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Spleen, 30 mg/kg/day MOPA, Animal 149

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_149s

value: route of_exposure:Oral gavage


title: Male Spleen, 30 mg/kg/day MOPA, Animal 147

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_147s

value: Male


title: Male Spleen, 30 mg/kg/day MOPA, Animal 145

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_145s


title: Male Spleen, 100 mg/kg/day MOPA, Animal 151

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_151s


title: Male Spleen, 10 mg/kg/day MOPA, Animal 142

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_142s

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Female Spleen, 0.01 mg/kg/day MOPA, Animal 168

description:
etap_mopa_spleen_female_counts.csv
Plate_27_MOPA_spleef_168s

value: Female

value: Spleen

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Male Spleen, 10 mg/kg/day MOPA, Animal 140

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_140s

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: No Issue


title: Male Spleen, 10 mg/kg/day MOPA, Animal 141

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_141s


title: Male Spleen, 10 mg/kg/day MOPA, Animal 144

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_144s


title: Male Spleen, 3 mg/kg/day MOPA, Animal 139

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_139s

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: Male Spleen, 3 mg/kg/day MOPA, Animal 138

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_138s

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Spleen, 3 mg/kg/day MOPA, Animal 136

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_136s

value: route of_exposure:Oral gavage


title: Male Spleen, 3 mg/kg/day MOPA, Animal 137

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_137s

value: Male


title: Male Spleen, 3 mg/kg/day MOPA, Animal 135

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_135s


title: Male Spleen, 1 mg/kg/day MOPA, Animal 134

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_134s

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Male Spleen, 100 mg/kg/day MOPA, Animal 154

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_154s

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Male Spleen, 1 mg/kg/day MOPA, Animal 132

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_132s

value: Spleen


title: Male Spleen, 0.3 mg/kg/day MOPA, Animal 128

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_128s

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Male Spleen, 1 mg/kg/day MOPA, Animal 133

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_133s

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: No Issue


title: Male Spleen, 0.3 mg/kg/day MOPA, Animal 127

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_127s


title: Male Spleen, 0.3 mg/kg/day MOPA, Animal 126

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_126s


title: Male Spleen, 0.3 mg/kg/day MOPA, Animal 125

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_125s


title: Male Spleen, 0.1 mg/kg/day MOPA, Animal 124

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_124s

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: Male Spleen, 10 mg/kg/day MOPA, Animal 143

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_143s

value: Male

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Male Spleen, 0.1 mg/kg/day MOPA, Animal 123

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_123s


title: Male Spleen, 0.1 mg/kg/day MOPA, Animal 120

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_120s


title: Male Spleen, 0.1 mg/kg/day MOPA, Animal 122

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_122s


title: Male Spleen, 0.1 mg/kg/day MOPA, Animal 121

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_121s


title: Male Spleen, 0.01 mg/kg/day MOPA, Animal 115

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_115s

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Male Spleen, Vehicle Control, Animal 114

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_114s

value: Spleen

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Spleen, Vehicle Control, Animal 113

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_113s

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: No Issue


title: Male Spleen, 0.01 mg/kg/day MOPA, Animal 117

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_117s


title: Male Spleen, Vehicle Control, Animal 112

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_112s


title: Male Spleen, Vehicle Control, Animal 110

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_110s


title: Male Spleen, Vehicle Control, Animal 109

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_109s


title: Male Spleen, Vehicle Control, Animal 107

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_107s


title: Male Spleen, Vehicle Control, Animal 108

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_108s


title: Male Spleen, 1 mg/kg/day MOPA, Animal 131

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_131s

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Female Kidney, 300 mg/kg/day MOPA, Animal 210

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_210k

source_name: Kidney

value: Female

value: Kidney

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Male Spleen, 0.3 mg/kg/day MOPA, Animal 129

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_129s

value: Male

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage


title: Male Spleen, 1 mg/kg/day MOPA, Animal 130

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_130s

value: Spleen

value: Sprague Dawley


title: Female Kidney, 100 mg/kg/day MOPA, Animal 205

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_205k

value: 10-12 weeks post acclimation

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: No Issue


title: Female Kidney, 100 mg/kg/day MOPA, Animal 207

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_207k

value: Female

value: Kidney


title: Female Kidney, 300 mg/kg/day MOPA, Animal 209

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_209k

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day


title: Female Kidney, 100 mg/kg/day MOPA, Animal 203

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_203k


title: Female Kidney, 100 mg/kg/day MOPA, Animal 206

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_206k


title: Male Spleen, 0.01 mg/kg/day MOPA, Animal 119

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_119s

value: Male

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Female Kidney, 30 mg/kg/day MOPA, Animal 202

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_202k

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Kidney, 30 mg/kg/day MOPA, Animal 201

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_201k

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: route of_exposure:Oral gavage


title: Male Spleen, 0.01 mg/kg/day MOPA, Animal 116

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_116s

value: Spleen


title: Female Kidney, 30 mg/kg/day MOPA, Animal 200

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_200k

value: No Issue


title: Male Spleen, 0.01 mg/kg/day MOPA, Animal 118

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_118s


title: Female Kidney, 10 mg/kg/day MOPA, Animal 196

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_196k

value: Female

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Female Kidney, 30 mg/kg/day MOPA, Animal 198

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_198k

value: Kidney


title: Female Kidney, 10 mg/kg/day MOPA, Animal 197

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_197k


title: Female Kidney, 30 mg/kg/day MOPA, Animal 199

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_199k


title: Female Kidney, 10 mg/kg/day MOPA, Animal 193

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_193k


title: Female Kidney, 10 mg/kg/day MOPA, Animal 195

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_195k


title: Female Kidney, 10 mg/kg/day MOPA, Animal 194

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_194k


title: Male Spleen, Vehicle Control, Animal 111

description:
etap_mopa_spleen_male_counts.csv
Plate_26_MOPA_spleem_111s

value: Male

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Kidney, 3 mg/kg/day MOPA, Animal 189

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_189k

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: Female Kidney, 1 mg/kg/day MOPA, Animal 186

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_186k

value: Sprague Dawley

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Kidney, 3 mg/kg/day MOPA, Animal 191

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_191k

value: Female

value: 10-12 weeks post acclimation

value: route of_exposure:Oral gavage

value: No Issue


title: Female Kidney, 3 mg/kg/day MOPA, Animal 190

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_190k

value: Kidney


title: Female Kidney, 3 mg/kg/day MOPA, Animal 188

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_188k


title: Female Kidney, 300 mg/kg/day MOPA, Animal 208

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_208k

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Female Kidney, 1 mg/kg/day MOPA, Animal 187

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_187k


title: Female Kidney, 1 mg/kg/day MOPA, Animal 185

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_185k


title: Female Kidney, 100 mg/kg/day MOPA, Animal 204

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_204k

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Female Kidney, 1 mg/kg/day MOPA, Animal 184

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_184k


title: Female Kidney, 1 mg/kg/day MOPA, Animal 183

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_183k


title: Female Kidney, 0.3 mg/kg/day MOPA, Animal 180

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_180k

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Female Kidney, 0.1 mg/kg/day MOPA, Animal 177

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_177k

value: Sprague Dawley

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: Female Kidney, 0.1 mg/kg/day MOPA, Animal 176

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_176k

value: Female

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Kidney, 0.3 mg/kg/day MOPA, Animal 179

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_179k

value: Kidney

value: route of_exposure:Oral gavage

value: No Issue


title: Female Kidney, 0.1 mg/kg/day MOPA, Animal 175

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_175k


title: Female Kidney, 0.01 mg/kg/day MOPA, Animal 172

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_172k

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Female Kidney, 0.1 mg/kg/day MOPA, Animal 174

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_174k


title: Female Kidney, 0.1 mg/kg/day MOPA, Animal 173

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_173k


title: Female Kidney, 3 mg/kg/day MOPA, Animal 192

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_192k

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: EP000004A12_4_0.497018CF_TC00503572_P22

description:
EP000004A12_4_0.497018CF
TC00503572_P22

data_processing:
Each FASTQ file was aligned to the probe sequences in the hWTv1 assay using HISAT2 v2.1.0 with spliced alignment disabled.
Aligned reads in SAM format were processed with SAMtools v1.9 to compute the number of uniquely aligned reads for each probe. Probe counts and associated meta-data for each well were stored for analysis using MongoDB v3.6.14.
Assembly: hWTv1
Supplementary files format and content: Processed data provided as a single table of counts for all probes x all samples

organism: Homo sapiens

source_name: MCF7 Cells

growth_protocol: Experiments were performed using MCF7 breast adenocarcinoma cells (ATCC® HTB-22) cultured in Dulbecco’s Modified Eagle Medium (DMEM) + 10% heat-inactivated fetal bovine serum (FBS) containing 1× Gibco® penicillin-streptomycin-glutamine (PSG). For each independent culture, a single vial of MCF7 cells was thawed, subject to a uniform expansion and passaging schedule to generate enough cells for seeding in 384-well plates and to ensure that cells were tested at a consistent passage number across all replicate cultures. At the time of seeding into assay plates (Corning 3985BC), cell suspensions were volumetrically adjusted with growth media to a concentration of 2.5x10^2 cells / µL. Forty microliters of cell suspension was then dispensed into each assay well using a MultiFlo FX multi-mode dispenser equipped with a 10 µL dispensing cassette (BioTek, Winooski, VT) in order to achieve an initial seeding density of 10,000 live cells / well. Cells were dispensed into all wells of the HTTr assay plates except column 1 to allow for addition of transcriptomic reference samples to be added to each HTTr assay plate following lysate preparation. After seeding, assay plates were placed in a humidified incubator (37°C) with 5% CO2 atmosphere for 24 h prior to treatment.

extract_protocol:
Six hours after water extract treatment, HTTr assay plates were removed from the incubator and media in each assay well drained to a residual volume of 10 µL. A 10 µL volume of 2× BioSpyder lysis buffer was dispensed into each assay well. Then, 20 µL volumes of Universal Human Reference RNA (UHRR), Human Brain Reference RNA (HBRR), bulk lysates from MCF7 cells treated with 0.5% DMSO (BL DMSO) or 1 µM trichostatin A (BL TSA), and lysis buffer blans were dispensed into the first column of each assay plate. The plates were sealed with an adhesive aluminum plate cover and incubated at room temperature, protected from light, for 30 min. The plates were then stored at -80°C prior to shipment to BioSpyder, Inc.
Samples were analyzed by BioSpyder using a custom-attenuated version of the TempO-Seq human whole transcriptome version 1 (hWTv1) assay, which includes 21,111 probes covering 19,287 genes. In brief, 2 µL of each lysate was hybridized with 2 µL of detector oligos from the hWTv1 assay using the following thermal cycler protocol: 10 min at 70°C, followed by gradual decrease to 45°C over 49 min, terminating with 45°C incubation for 16-24 hours. Excess oligos were then removed via nuclease digestion (90 min at 37°C) and hybridized detector oligos were ligated (60 min at 37°) following respective additions of 24 µL TempO-Seq nuclease and ligation mixes. RNA/DNA duplexes were then heat-denatured and 10 µL of each ligation product was transferred to an amplification microplate containing 10 µL of PCR master mix per well. Ligation products were then uniquely labeled during product amplification (10 min at 37°C, 2 min at 95°C, 6 cycles of 95°C for 30 s, 54°C for 30 s, 72°C for 120 s, 16 cycles of 95°C for 30s and 72°C for 120s, followed by 72°C for 60 s) with well coordinate-specific “barcoded” primer pairs containing universal adaptors for sequencing. Samples were then pooled into a series of three sequencing libraries (1 for each plate). Pooled sequencing libraries were then distributed across multiple lanes of a HiSeq dual flow cell and analyzed on a HiSeq 2500 Ultra-High-Throughput Sequencing System (Illumina, San Diego, CA).

treatment_protocol: DMSO-solubilized water extracts collected from each sampling site were shipped frozen to US EPA and stored at  80°C prior to dose plate preparation. Eight-point dilution series (1/2 log10 spacing) of each stock sample was prepared in a LabCyte Echo-qualified 384-well low dead volume (384LDV) plate. Transcriptomics reference chemicals for MCF7 cells (genistein, trichostatin A, sirolimus) were solubilized as 200× dosing solutions corresponding to nominal test concentrations of 10, 1 and 0.1 µM, respectively. Triplicate wells of dosing solutions for each of the reference chemicals were added to the dose plates along with quadruplicate wells of pure DMSO as a vehicle control. The dose plate was then sealed with a Nunc aluminum adhesive plate cover and stored at -80°C until use. On the first day of dosing, the dose plate was thawed to room temperature inside a desiccator, centrifuged briefly to ensure even distribution of the dose solution in each well and unsealed. A LabCyte Echo 550 acoustic dispenser was then used to transfer 200 nL of dosing solutions to the assay plates containing 40 uL of culture media. The final DMSO concentration was 0.5% for all treatment, reference treatment and vehicle control wells. Well coordinates were uniquely randomized on each assay plate with respect to treatment so that any potential edge-well effects were distributed in an unbiased manner across all possible treatment conditions.

tag: cell line

value: 6h exposure of 0.4970179 uM of MCF7_HTTr_Water_Sample_12

tag: media

value: DMEM + 10% HI-FBS

tag: chemical name

tag: chemical sample_id

tag: chemical concentration

tag: dose level

tag: exposure time

tag: assay plate

tag: assay plate_well

tag: water type

value: Surface Water


title: Female Kidney, 0.01 mg/kg/day MOPA, Animal 171

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_171k

value: Sprague Dawley


title: EP000004A11_6_4.716981CF_TC00503572_P12

description:
EP000004A11_6_4.716981CF
TC00503572_P12

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_11

value: Blank


title: EP000004A11_7_12.711864CF_TC00503572_P07

description:
EP000004A11_7_12.711864CF
TC00503572_P07

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_11


title: EP000004B06_6_4.716981CF_TC00503572_P20

description:
EP000004B06_6_4.716981CF
TC00503572_P20

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_18


title: Female Kidney, 0.01 mg/kg/day MOPA, Animal 170

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_170k

value: Female

value: Kidney

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Kidney, 0.3 mg/kg/day MOPA, Animal 181

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_181k

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004A03_2_0.049970CF_TC00503572_P05

description:
EP000004A03_2_0.049970CF
TC00503572_P05

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_3


title: Female Kidney, 0.01 mg/kg/day MOPA, Animal 168

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_168k

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: SIRO_TC00503572_O23

description:
SIRO
TC00503572_O23

value: 6h exposure of 0.1 uM of Sirolimus

value: DMEM + 10% HI-FBS

value: Sirolimus


title: Female Kidney, 0.01 mg/kg/day MOPA, Animal 169

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_169k

value: Sprague Dawley


title: EP000004B02_3_0.149731CF_TC00503572_P08

description:
EP000004B02_3_0.149731CF
TC00503572_P08

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_14

value: Blank


title: Female Kidney, Vehicle Control, Animal 167

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_167k

value: Female

value: Kidney

value: 10-12 weeks post acclimation

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: EP000004A01_8_50.000000CF_TC00503572_O22

description:
EP000004A01_8_50.000000CF
TC00503572_O22

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_1

value: 50 CF

value: Reclaimed Water


title: Female Kidney, Vehicle Control, Animal 166

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_166k

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004B03_1_0.014967CF_TC00503572_O20

description:
EP000004B03_1_0.014967CF
TC00503572_O20

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_15

value: DMEM + 10% HI-FBS

value: Wastewater


title: Female Kidney, Vehicle Control, Animal 165

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_165k

value: Sprague Dawley


title: EP000004A09_2_0.049970CF_TC00503572_O19

description:
EP000004A09_2_0.049970CF
TC00503572_O19

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_9

value: Blank


title: Female Kidney, Vehicle Control, Animal 164

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_164k

value: Female

value: Kidney


title: Female Kidney, Vehicle Control, Animal 163

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_163k

value: 10-12 weeks post acclimation

value: Deionized water control, 5-day repeat exposure, oral gavage


title: EP000004A10_7_12.711864CF_TC00503572_O15

description:
EP000004A10_7_12.711864CF
TC00503572_O15

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_10


title: GEN_TC00503572_O18

description:
GEN
TC00503572_O18

value: 6h exposure of 10 uM of Genistein

value: Genistein

value: 10 uM


title: Female Kidney, Vehicle Control, Animal 162

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_162k

value: dose:0 mg/kg/day

value: dose group:0

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004A10_4_0.497018CF_TC00503572_O14

description:
EP000004A10_4_0.497018CF
TC00503572_O14

value: 6h exposure of 0.4970179 uM of MCF7_HTTr_Water_Sample_10


title: EP000004B02_6_4.716981CF_TC00503572_O11

description:
EP000004B02_6_4.716981CF
TC00503572_O11

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_14

value: DMEM + 10% HI-FBS


title: Female Kidney, Vehicle Control, Animal 161

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_161k

value: Sprague Dawley

value: route of_exposure:Oral gavage

value: No Issue


title: Female Kidney, Vehicle Control, Animal 160

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_160k

value: Female


title: EP000004A03_6_4.716981CF_TC00503572_O12

description:
EP000004A03_6_4.716981CF
TC00503572_O12

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_3

value: Surface Water


title: EP000004B02_8_50.000000CF_TC00503572_O10

description:
EP000004B02_8_50.000000CF
TC00503572_O10

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_14

value: 50 CF

value: Blank


title: EP000004B01_3_0.149731CF_TC00503572_O24

description:
EP000004B01_3_0.149731CF
TC00503572_O24

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_13

value: Wastewater


title: Male Kidney, 300 mg/kg/day MOPA, Animal 157

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_157k

value: Male

value: Kidney

value: 10-12 weeks post acclimation

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: Male Kidney, 300 mg/kg/day MOPA, Animal 158

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_158k

value: Sprague Dawley

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004A01_5_1.473477CF_TC00503572_O05

description:
EP000004A01_5_1.473477CF
TC00503572_O05

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_1

value: DMEM + 10% HI-FBS

value: Reclaimed Water


title: EP000004A10_5_1.473477CF_TC00503572_N24

description:
EP000004A10_5_1.473477CF
TC00503572_N24

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_10


title: Male Kidney, 100 mg/kg/day MOPA, Animal 154

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_154k

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: route of_exposure:Oral gavage

value: No Issue


title: TSA_TC00503572_N22

description:
TSA
TC00503572_N22

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A

value: 1 uM


title: EP000004A11_4_0.497018CF_TC00503572_N15

description:
EP000004A11_4_0.497018CF
TC00503572_N15

value: 6h exposure of 0.4970179 uM of MCF7_HTTr_Water_Sample_11

value: Blank


title: EP000004B06_3_0.149731CF_TC00503572_N16

description:
EP000004B06_3_0.149731CF
TC00503572_N16

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_18

value: Surface Water


title: Male Kidney, 100 mg/kg/day MOPA, Animal 152

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_152k

value: Male

value: Kidney

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Kidney, 300 mg/kg/day MOPA, Animal 156

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_156k

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: EP000004B01_4_0.497018CF_TC00503572_N12

description:
EP000004B01_4_0.497018CF
TC00503572_N12

value: 6h exposure of 0.4970179 uM of MCF7_HTTr_Water_Sample_13

value: DMEM + 10% HI-FBS

value: Wastewater


title: Male Kidney, 300 mg/kg/day MOPA, Animal 155

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_155k

value: route of_exposure:Oral gavage

value: No Issue


title: Male Kidney, 100 mg/kg/day MOPA, Animal 153

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_153k

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: EP000004A01_1_0.014967CF_TC00503572_N14

description:
EP000004A01_1_0.014967CF
TC00503572_N14

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_1

value: Reclaimed Water


title: Male Kidney, 30 mg/kg/day MOPA, Animal 149

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_149k

value: Male

value: Kidney

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Male Kidney, 100 mg/kg/day MOPA, Animal 150

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_150k

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004A05_7_12.711864CF_TC00503572_N05

description:
EP000004A05_7_12.711864CF
TC00503572_N05

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_5

value: DMEM + 10% HI-FBS

value: Surface Water


title: EP000004A02_7_12.711864CF_TC00503572_N09

description:
EP000004A02_7_12.711864CF
TC00503572_N09

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_2

value: Wastewater


title: Male Kidney, 300 mg/kg/day MOPA, Animal 159

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_159k

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9

value: route of_exposure:Oral gavage

value: No Issue


title: Female Kidney, 0.3 mg/kg/day MOPA, Animal 178

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_178k

value: Female

value: Kidney

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: Male Kidney, 30 mg/kg/day MOPA, Animal 147

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_147k

value: Male

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Male Kidney, 30 mg/kg/day MOPA, Animal 146

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_146k

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004B01_1_0.014967CF_TC00503572_M19

description:
EP000004B01_1_0.014967CF
TC00503572_M19

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_13

value: DMEM + 10% HI-FBS

value: Wastewater


title: DMSO_TC00503572_M17

description:
DMSO
TC00503572_M17

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: Male Kidney, 10 mg/kg/day MOPA, Animal 144

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_144k

value: Kidney

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004B06_5_1.473477CF_TC00503572_M15

description:
EP000004B06_5_1.473477CF
TC00503572_M15

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_18

value: Surface Water


title: Male Kidney, 10 mg/kg/day MOPA, Animal 142

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_142k

value: Male

value: Sprague Dawley

value: 10-12 weeks post acclimation


title: EP000004B05_3_0.149731CF_TC00503572_M13

description:
EP000004B05_3_0.149731CF
TC00503572_M13

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_17

value: Drinking Water


title: EP000004A09_1_0.014967CF_TC00503572_M16

description:
EP000004A09_1_0.014967CF
TC00503572_M16

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_9

value: DMEM + 10% HI-FBS

value: Blank


title: Male Kidney, 10 mg/kg/day MOPA, Animal 141

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_141k

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Kidney, 100 mg/kg/day MOPA, Animal 151

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_151k

value: Kidney

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: EP000004B06_7_12.711864CF_TC00503572_N10

description:
EP000004B06_7_12.711864CF
TC00503572_N10

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_18


title: EP000004B06_2_0.049970CF_TC00503572_M10

description:
EP000004B06_2_0.049970CF
TC00503572_M10

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_18


title: EP000004A11_8_50.000000CF_TC00503572_M06

description:
EP000004A11_8_50.000000CF
TC00503572_M06

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_11

value: 50 CF


title: EP000004A07_2_0.049970CF_TC00503572_M09

description:
EP000004A07_2_0.049970CF
TC00503572_M09

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_7

value: Reclaimed Water


title: Female Kidney, 0.3 mg/kg/day MOPA, Animal 182

description:
etap_mopa_kidney_female_counts.csv
Plate_25_MOPA_kidnef_182k

value: Female

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3

value: route of_exposure:Oral gavage

value: No Issue


title: Male Kidney, 10 mg/kg/day MOPA, Animal 140

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_140k

value: Male

value: Kidney

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Kidney, 3 mg/kg/day MOPA, Animal 139

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_139k

value: 3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: Male Kidney, 3 mg/kg/day MOPA, Animal 136

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_136k


title: EP000004B06_8_50.000000CF_TC00503572_L15

description:
EP000004B06_8_50.000000CF
TC00503572_L15

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_18

value: DMEM + 10% HI-FBS

value: 50 CF

value: Surface Water


title: Male Kidney, 3 mg/kg/day MOPA, Animal 138

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_138k

value: Sprague Dawley

value: 10-12 weeks post acclimation


title: EP000004A04_7_12.711864CF_TC00503572_M03

description:
EP000004A04_7_12.711864CF
TC00503572_M03

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_4

value: Drinking Water


title: Male Kidney, 3 mg/kg/day MOPA, Animal 137

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_137k

value: Male

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004A08_6_4.716981CF_TC00503572_L12

description:
EP000004A08_6_4.716981CF
TC00503572_L12

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_8

value: Wastewater


title: Male Kidney, 3 mg/kg/day MOPA, Animal 135

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_135k

value: Kidney

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004A10_1_0.014967CF_TC00503572_L13

description:
EP000004A10_1_0.014967CF
TC00503572_L13

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_10

value: Blank


title: EP000004A04_8_50.000000CF_TC00503572_M24

description:
EP000004A04_8_50.000000CF
TC00503572_M24

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_4


title: Male Kidney, 30 mg/kg/day MOPA, Animal 145

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_145k

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Male Kidney, 1 mg/kg/day MOPA, Animal 134

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_134k

value: Sprague Dawley

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: Male Kidney, 10 mg/kg/day MOPA, Animal 143

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_143k

value: Male

value: 10-12 weeks post acclimation

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: Male Kidney, 1 mg/kg/day MOPA, Animal 132

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_132k

value: Kidney

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004B03_6_4.716981CF_TC00503572_L02

description:
EP000004B03_6_4.716981CF
TC00503572_L02

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_15

value: DMEM + 10% HI-FBS

value: Wastewater


title: Untrtd_TC00503572_L07

description:
Untrtd
TC00503572_L07

value: untreated


title: Male Kidney, 1 mg/kg/day MOPA, Animal 133

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_133k

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004B03_8_50.000000CF_TC00503572_K23

description:
EP000004B03_8_50.000000CF
TC00503572_K23

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_15

value: 50 CF


title: EP000004A04_2_0.049970CF_TC00503572_K22

description:
EP000004A04_2_0.049970CF
TC00503572_K22

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_4

value: Drinking Water


title: Male Kidney, 1 mg/kg/day MOPA, Animal 130

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_130k

value: Male

value: Sprague Dawley

value: 1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: DMSO_TC00503572_K20

description:
DMSO
TC00503572_K20

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: Male Kidney, 1 mg/kg/day MOPA, Animal 131

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_131k

value: Kidney

value: 10-12 weeks post acclimation

value: route of_exposure:Oral gavage

value: No Issue


title: Male Kidney, 0.3 mg/kg/day MOPA, Animal 129

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_129k

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Kidney, 0.3 mg/kg/day MOPA, Animal 128

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_128k


title: EP000004B04_6_4.716981CF_TC00503572_K18

description:
EP000004B04_6_4.716981CF
TC00503572_K18

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_16

value: DMEM + 10% HI-FBS

value: Reclaimed Water


title: EP000004A02_8_50.000000CF_TC00503572_K16

description:
EP000004A02_8_50.000000CF
TC00503572_K16

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_2

value: 50 CF

value: Wastewater


title: Male Kidney, 0.3 mg/kg/day MOPA, Animal 125

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_125k

value: Male

value: Sprague Dawley


title: EP000004A05_3_0.149731CF_TC00503572_K12

description:
EP000004A05_3_0.149731CF
TC00503572_K12

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_5

value: Surface Water


title: EP000004A03_1_0.014967CF_TC00503572_K17

description:
EP000004A03_1_0.014967CF
TC00503572_K17

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_3


title: Male Kidney, 0.1 mg/kg/day MOPA, Animal 123

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_123k

value: Kidney

value: 10-12 weeks post acclimation

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: route of_exposure:Oral gavage


title: EP000004B03_2_0.049970CF_TC00503572_K10

description:
EP000004B03_2_0.049970CF
TC00503572_K10

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_15


title: EP000004A11_3_0.149731CF_TC00503572_K15

description:
EP000004A11_3_0.149731CF
TC00503572_K15

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_11

value: DMEM + 10% HI-FBS

value: Blank


title: Male Kidney, 0.3 mg/kg/day MOPA, Animal 127

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_127k

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: No Issue


title: EP000004A12_2_0.049970CF_TC00503572_L09

description:
EP000004A12_2_0.049970CF
TC00503572_L09

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_12

value: Surface Water


title: Male Kidney, 0.1 mg/kg/day MOPA, Animal 121

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_121k

value: Male

value: Kidney

value: Sprague Dawley


title: EP000004A01_6_4.716981CF_TC00503572_K08

description:
EP000004A01_6_4.716981CF
TC00503572_K08

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_1

value: Reclaimed Water


title: EP000004A08_5_1.473477CF_TC00503572_K07

description:
EP000004A08_5_1.473477CF
TC00503572_K07

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_8

value: Wastewater


title: Male Kidney, 0.1 mg/kg/day MOPA, Animal 122

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_122k

value: 10-12 weeks post acclimation

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: route of_exposure:Oral gavage


title: EP000004A01_7_12.711864CF_TC00503572_K04

description:
EP000004A01_7_12.711864CF
TC00503572_K04

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_1

value: DMEM + 10% HI-FBS


title: Male Kidney, 0.01 mg/kg/day MOPA, Animal 119

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_119k

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)

value: No Issue


title: EP000004B02_7_12.711864CF_TC00503572_K02

description:
EP000004B02_7_12.711864CF
TC00503572_K02

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_14

value: Blank


title: Male Kidney, 0.01 mg/kg/day MOPA, Animal 118

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_118k

value: Male

value: Kidney

value: Sprague Dawley


title: Male Kidney, 0.01 mg/kg/day MOPA, Animal 117

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_117k

value: 10-12 weeks post acclimation


title: EP000004B04_1_0.014967CF_TC00503572_J22

description:
EP000004B04_1_0.014967CF
TC00503572_J22

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_16

value: Reclaimed Water


title: EP000004A03_3_0.149731CF_TC00503572_J21

description:
EP000004A03_3_0.149731CF
TC00503572_J21

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_3

value: Surface Water


title: Male Kidney, 0.01 mg/kg/day MOPA, Animal 116

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_116k

value: route of_exposure:Oral gavage


title: EP000004B03_7_12.711864CF_TC00503572_J19

description:
EP000004B03_7_12.711864CF
TC00503572_J19

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_15

value: DMEM + 10% HI-FBS

value: Wastewater


title: EP000004A12_7_12.711864CF_TC00503572_J18

description:
EP000004A12_7_12.711864CF
TC00503572_J18

value: 6h exposure of 12.7118644 uM of MCF7_HTTr_Water_Sample_12


title: Male Kidney, 0.3 mg/kg/day MOPA, Animal 126

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_126k

value: 0.3 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Kidney, Vehicle Control, Animal 114

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_114k

value: Male

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: No Issue


title: Male Kidney, 0.01 mg/kg/day MOPA, Animal 115

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_115k

value: Kidney

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: 0.01 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: Male Kidney, Vehicle Control, Animal 113

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_113k

value: route of_exposure:Oral gavage


title: Male Kidney, Vehicle Control, Animal 112

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_112k


title: Male Kidney, Vehicle Control, Animal 111

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_111k


title: EP000004A08_2_0.049970CF_TC00503572_J15

description:
EP000004A08_2_0.049970CF
TC00503572_J15

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_8

value: DMEM + 10% HI-FBS

value: Wastewater


title: EP000004A05_1_0.014967CF_TC00503572_J06

description:
EP000004A05_1_0.014967CF
TC00503572_J06

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_5

value: Surface Water


title: EP000004A07_3_0.149731CF_TC00503572_J05

description:
EP000004A07_3_0.149731CF
TC00503572_J05

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_7

value: Reclaimed Water


title: EP000004A12_6_4.716981CF_TC00503572_J08

description:
EP000004A12_6_4.716981CF
TC00503572_J08

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_12


title: Male Kidney, Vehicle Control, Animal 109

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_109k

value: Male

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Male Kidney, 0.1 mg/kg/day MOPA, Animal 124

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_124k

value: Kidney

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: No Issue


title: Male Kidney, Vehicle Control, Animal 108

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_108k

value: route of_exposure:Oral gavage


title: Male Kidney, Vehicle Control, Animal 110

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_110k


title: Female Liver, 300 mg/kg/day MOPA, Animal 211

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_211l

source_name: Liver

value: Female

value: Liver

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9


title: DMSO_TC00503572_J02

description:
DMSO
TC00503572_J02

value: 0.5% DMSO vehicle control

value: DMEM + 10% HI-FBS

value: DMSO

value: 0 uM


title: EP000004B05_1_0.014967CF_TC00503572_J14

description:
EP000004B05_1_0.014967CF
TC00503572_J14

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_17

value: Drinking Water


title: EP000004A01_4_0.497018CF_TC00503572_J03

description:
EP000004A01_4_0.497018CF
TC00503572_J03

value: 6h exposure of 0.4970179 uM of MCF7_HTTr_Water_Sample_1

value: Reclaimed Water


title: Male Kidney, Vehicle Control, Animal 107

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_107k

value: Male

value: Kidney

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: Deionized water control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Lysis Buffer_TC00503572_J01

description:
Lysis Buffer
TC00503572_J01

source_name: Lysis Buffer

value: NA (Universal Human Reference RNA)

value: untreated


title: Female Liver, 300 mg/kg/day MOPA, Animal 210

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_210l

value: Female

value: Liver

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:300 mg/kg/day

value: dose group:9

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004A03_5_1.473477CF_TC00503572_I20

description:
EP000004A03_5_1.473477CF
TC00503572_I20

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_3

value: DMEM + 10% HI-FBS

value: Surface Water


title: Female Liver, 300 mg/kg/day MOPA, Animal 209

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_209l

value: Sprague Dawley

value: 10-12 weeks post acclimation


title: TSA_TC00503572_I19

description:
TSA
TC00503572_I19

value: 6h exposure of 1 uM of Trichostatin A

value: Trichostatin A

value: 1 uM


title: Female Liver, 100 mg/kg/day MOPA, Animal 207

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_207l

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Liver, 300 mg/kg/day MOPA, Animal 208

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_208l

value: Female

value: Liver

value: 300 mg/kg/day MOPA, 5-day repeat exposure, oral gavage


title: EP000004A08_8_50.000000CF_TC00503572_I22

description:
EP000004A08_8_50.000000CF
TC00503572_I22

value: 6h exposure of 50 uM of MCF7_HTTr_Water_Sample_8

value: 50 CF

value: Wastewater


title: EP000004A08_3_0.149731CF_TC00503572_I16

description:
EP000004A08_3_0.149731CF
TC00503572_I16

value: 6h exposure of 0.1497305 uM of MCF7_HTTr_Water_Sample_8

value: DMEM + 10% HI-FBS


title: EP000004A09_5_1.473477CF_TC00503572_J12

description:
EP000004A09_5_1.473477CF
TC00503572_J12

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_9

value: Blank


title: Female Liver, 100 mg/kg/day MOPA, Animal 205

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_205l

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: route of_exposure:Oral gavage

value: No Issue


title: Female Liver, 100 mg/kg/day MOPA, Animal 206

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_206l

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day


title: EP000004A04_1_0.014967CF_TC00503572_I12

description:
EP000004A04_1_0.014967CF
TC00503572_I12

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_4

value: Drinking Water


title: EP000004B02_5_1.473477CF_TC00503572_I15

description:
EP000004B02_5_1.473477CF
TC00503572_I15

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_14


title: EP000004B01_2_0.049970CF_TC00503572_I11

description:
EP000004B01_2_0.049970CF
TC00503572_I11

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_13


title: Female Liver, 100 mg/kg/day MOPA, Animal 204

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_204l

value: Female

value: Liver

value: dose group:8

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: EP000004A07_1_0.014967CF_TC00503572_J04

description:
EP000004A07_1_0.014967CF
TC00503572_J04

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_7

value: DMEM + 10% HI-FBS

value: Reclaimed Water


title: EP000004A06_2_0.049970CF_TC00503572_I08

description:
EP000004A06_2_0.049970CF
TC00503572_I08

value: 6h exposure of 0.04997 uM of MCF7_HTTr_Water_Sample_6


title: Female Liver, 30 mg/kg/day MOPA, Animal 202

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_202l

value: Sprague Dawley

value: 10-12 weeks post acclimation

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: Female Liver, 100 mg/kg/day MOPA, Animal 203

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_203l

value: 100 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004A07_6_4.716981CF_TC00503572_I05

description:
EP000004A07_6_4.716981CF
TC00503572_I05

value: 6h exposure of 4.71698115 uM of MCF7_HTTr_Water_Sample_7


title: Female Liver, 30 mg/kg/day MOPA, Animal 201

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_201l

value: Female

value: Liver


title: DMSO_TC00503572_I04

description:
DMSO
TC00503572_I04

value: 0.5% DMSO vehicle control

value: DMSO

value: 0 uM


title: Untrtd_TC00503572_I02

description:
Untrtd
TC00503572_I02

value: untreated

value: DMEM + 10% HI-FBS


title: Female Liver, 30 mg/kg/day MOPA, Animal 200

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_200l

value: Sprague Dawley

value: chemical name:Perfluoro-3-methoxypropanoic acid (MOPA)


title: Female Liver, 30 mg/kg/day MOPA, Animal 199

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_199l

value: 10-12 weeks post acclimation

value: 30 mg/kg/day MOPA, 5-day repeat exposure, oral gavage


title: EP000004A02_1_0.014967CF_TC00503572_H24

description:
EP000004A02_1_0.014967CF
TC00503572_H24

value: 6h exposure of 0.01496735 uM of MCF7_HTTr_Water_Sample_2

value: Wastewater


title: Female Liver, 30 mg/kg/day MOPA, Animal 198

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_198l

value: dose:30 mg/kg/day

value: dose group:7


title: Lysis Buffer_TC00503572_I01

description:
Lysis Buffer
TC00503572_I01

value: NA (Universal Human Reference RNA)


title: Female Liver, 10 mg/kg/day MOPA, Animal 197

description:
etap_mopa_liver_female_counts.csv
Plate_23_MOPA_liverf_197l

value: 10 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6

value: route of_exposure:Oral gavage

value: No Issue


title: EP000004B05_5_1.473477CF_TC00503572_H21

description:
EP000004B05_5_1.473477CF
TC00503572_H21

value: 6h exposure of 1.4734774 uM of MCF7_HTTr_Water_Sample_17

value: Drinking Water


title: Male Kidney, 0.1 mg/kg/day MOPA, Animal 120

description:
etap_mopa_kidney_male_counts.csv
Plate_24_MOPA_kidnem_120k

value: Male

value: Kidney

value: 0.1 mg/kg/day MOPA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2