title: Pt 25, e11, p53 signature, stroma, LSP17731_Scan1 | 019 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_174

status: Public on Nov 22 2024

type: RNA

city: Little Rock

first: Yan

last: Cheng

state: Arkansas

address: 4301 W. Markham St.

department: Internal Medicine

country: USA

institute: University of Arkansas for Medical Sciences

description: Bone marrow biopsy

hyb_protocol: Following fragmentation, 10 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Drosophila Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.

scan_protocol: GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G2500A.

data_processing: The data were analyzed with Microarray Suite version 5.0 (MAS 5.0) using Affymetrix default analysis settings and global scaling as normalization method. The trimmed mean target intensity of each array was arbitrarily set to 100.

label: Biotin

molecule: total RNA

organism: Homo sapiens

source_name: Human bone marrow biopsy

label_protocol: Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 6 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).

growth_protocol: Bone marrow biopsies were harvested from the patient's iliac crest.

extract_protocol: Trizol extraction of total RNA was performed according to the manufacturer's instructions.

treatment_protocol: Bone marrow biopsies were used directly for RNA extraction.

tag: tissue

value: Newly diagnosed multiple myeloma


title: Pt 36, e11, incidental STIC, stroma, LSP18310_Scan1 | 002 | Full ROI

type: SRA

city: Boston

first: Clemens

last: Hug

state: MA

address: 200 Longwood Avenue

department: Harvard Program in Therapeutic Science

institute: Harvard Medical School

description: FFPE

library_source: transcriptomic

data_processing:
Raw sequencing data were processed to generate FASTQ files
Process FASTQ files through GeoMx NGS pipeline and convert to DCC files
Retreive DCC files
Transfer DCC files to GeoMx DSP for QC and normalisation by DSP software
Then we have Q3 normalised count matrix file (available with the publication as Supplementary File)
demultiplexed fastqs according to nanostring pipeline
Supplementary files format and content: DCC files are digital count files which have been processed from FASTQ files by nanostring pipeline
Library strategy: Spatial Transcriptomics

source_name: high grade serous ovarian carcinoma

extract_protocol:
5uM thickness section was processed according to GeoMx protocol provided by Nanostring
the libraries were prepared according to manufacturer's protocol (Nanostring)

value: high grade serous ovarian carcinoma

tag: cell type

value: stroma

tag: lesion type

value: incidental STIC

tag: brca status

value: WT

tag: primary cancer_stage

value: incidental

tag: patient id

value: Pt 36

tag: batch


title: Pt 36, e11, incidental STIC, epithelial, LSP18310_Scan1 | 001 | Full ROI

description: FFPE

value: epithelial


title: Newly diagnosed multiple myeloma_171

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_170

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_169

description: Bone marrow biopsy


title: Pt 36, e11, incidental STIC, stroma, LSP18310_Scan1 | 004 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_179

description: Bone marrow biopsy


title: Pt 36, e11, incidental STIC, epithelial, LSP18310_Scan1 | 003 | Full ROI

description: FFPE


title: Pt 36, e11, incidental STIC, epithelial, LSP18310_Scan1 | 005 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_177

description: Bone marrow biopsy


title: Pt 25, e11, STIC, stroma, LSP17731_Scan1 | 016 | Full ROI

description: FFPE

value: STIC

value: Mut

value: IIIC

value: Pt 25


title: Pt 36, e11, incidental STIC, stroma, LSP18310_Scan1 | 006 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_168

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_167

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_166

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_165

description: Bone marrow biopsy


title: Pt 36, e11, incidental STIC, epithelial, LSP18310_Scan1 | 007 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_164

description: Bone marrow biopsy


title: Pt 36, e11, incidental STIC, stroma, LSP18310_Scan1 | 009 | Full ROI

description: FFPE


title: Pt 36, e11, incidental STIC, epithelial, LSP18310_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 36, e11, incidental Fimbriae, stroma, LSP18310_Scan1 | 011 | Full ROI

description: FFPE

value: incidental Fimbriae


title: Newly diagnosed multiple myeloma_162

description: Bone marrow biopsy


title: Pt 36, e11, incidental Fimbriae, epithelial, LSP18310_Scan1 | 012 | Full ROI

description: FFPE


title: Pt 36, e11, incidental Fimbriae, epithelial, LSP18310_Scan1 | 010 | Full ROI

description: FFPE


title: Pt 36, e11, incidental Fimbriae, stroma, LSP18310_Scan1 | 013 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_163

description: Bone marrow biopsy


title: Pt 36, e11, incidental FT, epithelial, LSP18310_Scan1 | 014 | Full ROI

description: FFPE

value: incidental FT


title: Pt 36, e11, incidental FT, stroma, LSP18310_Scan1 | 015 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_159

description: Bone marrow biopsy


title: Pt 36, e11, incidental FT, epithelial, LSP18310_Scan1 | 016 | Full ROI

description: FFPE


title: Pt 36, e11, incidental FT, stroma, LSP18310_Scan1 | 017 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_161

description: Bone marrow biopsy


title: Pt 34, e14, incidental Fimbriae, epithelial, LSP19411_Scan1 | 023 | Full ROI

description: FFPE

value: Pt 34


title: Pt 36, e11, incidental FT, epithelial, LSP18310_Scan1 | 018 | Full ROI

description: FFPE


title: Pt 24, e11, STIC, epithelial, LSP17727_Scan1 | 001 | Full ROI

description: FFPE

value: IIIA

value: Pt 24


title: Newly diagnosed multiple myeloma_157

description: Bone marrow biopsy

value: Newly diagnosed multiple myeloma


title: Pt 36, e11, incidental FT, stroma, LSP18310_Scan1 | 019 | Full ROI

description: FFPE

value: high grade serous ovarian carcinoma


title: Pt 24, e11, STIC, stroma, LSP17727_Scan1 | 002 | Full ROI

description: FFPE

value: stroma


title: Newly diagnosed multiple myeloma_153

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_156

description: Bone marrow biopsy


title: Pt 24, e11, Inv Cancer, stroma, LSP17727_Scan1 | 007 | Full ROI

description: FFPE

value: Inv Cancer


title: Pt 24, e11, Inv Cancer, epithelial, LSP17727_Scan1 | 004 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_155

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_154

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_160

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_210

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_150

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_151

description: Bone marrow biopsy


title: Pt 24, e11, Inv Cancer, epithelial, LSP17727_Scan1 | 008 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_152

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_158

description: Bone marrow biopsy


title: Pt 24, e11, STIC, stroma, LSP17727_Scan1 | 010 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_147

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_149

description: Bone marrow biopsy


title: Pt 24, e11, Inv Cancer, epithelial, LSP17727_Scan1 | 013 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_146

description: Bone marrow biopsy


title: Pt 24, e11, Inv Cancer, stroma, LSP17727_Scan1 | 014 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_145

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_144

description: Bone marrow biopsy


title: Pt 38, e11, incidental STIC, epithelial, LSP18314_Scan1 | 003 | Full ROI

description: FFPE

value: incidental STIC

value: Pt 38


title: Newly diagnosed multiple myeloma_143

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_142

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_141

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_148

description: Bone marrow biopsy


title: Pt 38, e11, incidental STIC, stroma, LSP18314_Scan1 | 004 | Full ROI

description: FFPE

value: incidental


title: Pt 24, e11, STIC, epithelial, LSP17727_Scan1 | 009 | Full ROI

description: FFPE

value: epithelial


title: Pt 38, e11, incidental Fimbriae, epithelial, LSP18314_Scan1 | 023 | Full ROI

description: FFPE


title: Pt 28, e11, incidental p53sig, stroma, LSP17819_Scan1 | 002 | Full ROI

description: FFPE

value: incidental p53sig

value: Pt 28


title: Pt 38, e11, incidental STIC, stroma, LSP18314_Scan1 | 026 | Full ROI

description: FFPE

value: Mut


title: Newly diagnosed multiple myeloma_140

description: Bone marrow biopsy


title: Pt 28, e11, incidental p53sig, epithelial, LSP17819_Scan1 | 001 | Full ROI

description: FFPE


title: Pt 28, e11, incidental p53sig, epithelial, LSP17819_Scan1 | 003 | Full ROI

description: FFPE


title: Pt 28, e11, incidental FT, epithelial, LSP17819_Scan1 | 005 | Full ROI

description: FFPE


title: Pt 28, e11, incidental FT, epithelial, LSP17819_Scan1 | 004 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_138

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_135

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_136

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_134

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_137

description: Bone marrow biopsy


title: Pt 28, e11, incidental FT, epithelial, LSP17819_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 30


title: Newly diagnosed multiple myeloma_133

description: Bone marrow biopsy


title: Pt 38, e11, incidental Fimbriae, epithelial, LSP18314_Scan1 | 015 | Full ROI

description: FFPE

value: incidental Fimbriae


title: Newly diagnosed multiple myeloma_132

description: Bone marrow biopsy


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 002 | Full ROI

description: FFPE


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 003 | Full ROI

description: FFPE


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 004 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_139

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_125

description: Bone marrow biopsy


title: Pt 30, e11, incidental p53sig, stroma, LSP17851_Scan1 | 006 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_126

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_131

description: Bone marrow biopsy


title: Pt 28, e11, incidental FT, epithelial, LSP17819_Scan1 | 006 | Full ROI

description: FFPE

value: incidental FT


title: Pt 30, e11, incidental p53sig, stroma, LSP17851_Scan1 | 008 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_123

description: Bone marrow biopsy


title: Pt 30, e11, incidental p53sig, stroma, LSP17851_Scan1 | 009 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_124

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_129

description: Bone marrow biopsy


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 011 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_127

description: Bone marrow biopsy


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 012 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_121

description: Bone marrow biopsy


title: Pt 30, e11, incidental p53sig, epithelial, LSP17851_Scan1 | 010 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_122

description: Bone marrow biopsy


title: Pt 39, e11, incidental Fimbriae, epithelial, LSP18318_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 39


title: Pt 39, e11, incidental Fimbriae, stroma, LSP18318_Scan1 | 002 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_120

description: Bone marrow biopsy


title: Pt 39, e11, incidental Fimbriae, epithelial, LSP18318_Scan1 | 003 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_118

description: Bone marrow biopsy


title: Pt 39, e11, incidental Fimbriae, stroma, LSP18318_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 39, e11, incidental Fimbriae, stroma, LSP18318_Scan1 | 006 | Full ROI

description: FFPE


title: Pt 39, e11, incidental Fimbriae, epithelial, LSP18318_Scan1 | 007 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_114

description: Bone marrow biopsy


title: Pt 39, e11, incidental Fimbriae, stroma, LSP18318_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 39, e11, incidental Fimbriae, epithelial, LSP18318_Scan1 | 009 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_115

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_110

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_112

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_119

description: Bone marrow biopsy


title: Pt 39, e11, incidental Fimbriae, stroma, LSP18318_Scan1 | 012 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_109

description: Bone marrow biopsy


title: Pt 39, e11, incidental FT, epithelial, LSP18318_Scan1 | 013 | Full ROI

description: FFPE


title: Pt 39, e11, incidental Fimbriae, epithelial, LSP18318_Scan1 | 011 | Full ROI

description: FFPE


title: Pt 39, e11, incidental Fimbriae, stroma, LSP18318_Scan1 | 010 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_116

description: Bone marrow biopsy


title: Pt 39, e11, incidental FT, stroma, LSP18318_Scan1 | 014 | Full ROI

description: FFPE


title: Pt 39, e11, incidental FT, epithelial, LSP18318_Scan1 | 015 | Full ROI

description: FFPE


title: Pt 39, e11, incidental FT, stroma, LSP18318_Scan1 | 016 | Full ROI

description: FFPE


title: Pt 39, e11, incidental FT, epithelial, LSP18318_Scan1 | 017 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_105

description: Bone marrow biopsy


title: Pt 39, e11, incidental FT, stroma, LSP18318_Scan1 | 018 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_104

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_113

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_103

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_108

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_100

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_102

description: Bone marrow biopsy


title: Pt 39, e11, incidental Fimbriae, epithelial, LSP18318_Scan1 | 005 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_106

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_111

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_107

description: Bone marrow biopsy


title: Pt 39, e11, incidental FT, epithelial, LSP18318_Scan1 | 019 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_101

description: Bone marrow biopsy


title: Pt 27, e11, incidental FT, epithelial, LSP17803_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 27


title: Pt 39, e11, incidental FT, epithelial, LSP18318_Scan1 | 020 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_099

description: Bone marrow biopsy


title: Pt 39, e11, incidental FT, stroma, LSP18318_Scan1 | 021 | Full ROI

description: FFPE


title: Pt 27, e11, incidental FT, stroma, LSP17803_Scan1 | 002 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_098

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_096

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_095

description: Bone marrow biopsy


title: Pt 27, e11, incidental FT, epithelial, LSP17803_Scan1 | 003 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_097

description: Bone marrow biopsy


title: Pt 27, e11, incidental p53sig, epithelial, LSP17803_Scan1 | 005 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_094

description: Bone marrow biopsy


title: Pt 27, e11, incidental p53sig, epithelial, LSP17803_Scan1 | 006 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_093

description: Bone marrow biopsy


title: Pt 27, e11, incidental FT, stroma, LSP17803_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 27, e11, incidental p53sig, epithelial, LSP17803_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 40, e11, incidental STIC, epithelial, LSP18306_Scan1 | 003 | Full ROI

description: FFPE

value: WT

value: Pt 40


title: Newly diagnosed multiple myeloma_090

description: Bone marrow biopsy

value: Newly diagnosed multiple myeloma


title: Newly diagnosed multiple myeloma_092

description: Bone marrow biopsy


title: Pt 40, e11, incidental STIC, stroma, LSP18306_Scan1 | 002 | Full ROI

description: FFPE

value: high grade serous ovarian carcinoma

value: stroma


title: Pt 40, e11, incidental Fimbriae, stroma, LSP18306_Scan1 | 006 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_089

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_117

description: Bone marrow biopsy


title: Pt 40, e11, incidental Fimbriae, epithelial, LSP18306_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 40, e11, incidental Fimbriae, epithelial, LSP18306_Scan1 | 005 | Full ROI

description: FFPE


title: Pt 40, e11, incidental Fimbriae, epithelial, LSP18306_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 40, e11, incidental Fimbriae, stroma, LSP18306_Scan1 | 009 | Full ROI

description: FFPE


title: Pt 40, e11, incidental STIC, epithelial, LSP18306_Scan1 | 001 | Full ROI

description: FFPE

value: incidental STIC


title: Newly diagnosed multiple myeloma_088

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_085

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_087

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_091

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_086

description: Bone marrow biopsy


title: Pt 40, e11, incidental STIC, epithelial, LSP18306_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, stroma, LSP18302_Scan1 | 002 | Full ROI

description: FFPE

value: Pt 37


title: Pt 37, e11, incidental STIC, epithelial, LSP18302_Scan1 | 003 | Full ROI

description: FFPE

value: incidental


title: Newly diagnosed multiple myeloma_083

description: Bone marrow biopsy


title: Pt 37, e11, incidental STIC, epithelial, LSP18302_Scan1 | 001 | Full ROI

description: FFPE

value: epithelial


title: Pt 37, e11, incidental STIC, stroma, LSP18302_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, stroma, LSP18302_Scan1 | 006 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_081

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_082

description: Bone marrow biopsy


title: Pt 37, e11, incidental STIC, epithelial, LSP18302_Scan1 | 005 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_084

description: Bone marrow biopsy


title: Pt 37, e11, incidental STIC, epithelial, LSP18302_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, epithelial, LSP18302_Scan1 | 011 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, stroma, LSP18302_Scan1 | 010 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, stroma, LSP18302_Scan1 | 012 | Full ROI

description: FFPE


title: Pt 37, e11, incidental FT, stroma, LSP18302_Scan1 | 014 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_077

description: Bone marrow biopsy


title: Pt 37, e11, incidental FT, epithelial, LSP18302_Scan1 | 015 | Full ROI

description: FFPE


title: Pt 37, e11, incidental FT, stroma, LSP18302_Scan1 | 016 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, stroma, LSP18302_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 37, e11, incidental STIC, epithelial, LSP18302_Scan1 | 009 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_079

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_066

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_069

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_070

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_071

description: Bone marrow biopsy


title: Pt 37, e11, incidental Fimbriae, stroma, LSP18302_Scan1 | 018 | Full ROI

description: FFPE


title: Pt 37, e11, incidental Fimbriae, epithelial, LSP18302_Scan1 | 017 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_076

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_080

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_073

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_078

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_072

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_075

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_074

description: Bone marrow biopsy


title: Pt 37, e11, incidental FT, epithelial, LSP18302_Scan1 | 013 | Full ROI

description: FFPE


title: Pt 37, e11, incidental Fimbriae, stroma, LSP18302_Scan1 | 020 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_067

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_064

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_068

description: Bone marrow biopsy


title: Pt 6, e11, STIC, epithelial, LSP17723_Scan1 | 001 | Full ROI

description: FFPE

value: STIC

value: IC

value: Pt 6


title: Newly diagnosed multiple myeloma_062

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_063

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_065

description: Bone marrow biopsy


title: Pt 6, e11, STIC, epithelial, LSP17723_Scan1 | 002 | Full ROI

description: FFPE

value: Mut


title: Pt 6, e11, STIC, stroma, LSP17723_Scan1 | 003 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_060

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_059

description: Bone marrow biopsy


title: Pt 6, e11, STIC, stroma, LSP17723_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 6, e11, STIC, epithelial, LSP17723_Scan1 | 006 | Full ROI

description: FFPE


title: Pt 6, e11, STIC, stroma, LSP17723_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 6, e11, p53 signature, stroma, LSP17723_Scan1 | 016 | Full ROI

description: FFPE

value: p53 signature


title: Pt 6, e11, STIC, epithelial, LSP17723_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 6, e11, p53 signature, epithelial, LSP17723_Scan1 | 017 | Full ROI

description: FFPE


title: Pt 6, e11, p53 signature, stroma, LSP17723_Scan1 | 018 | Full ROI

description: FFPE


title: Pt 6, e11, p53 signature, epithelial, LSP17723_Scan1 | 019 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_057

description: Bone marrow biopsy


title: Pt 6, e11, p53 signature, stroma, LSP17723_Scan1 | 020 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_058

description: Bone marrow biopsy


title: Pt 6, e11, p53 signature, epithelial, LSP17723_Scan1 | 021 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_061

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_056

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_055

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_054

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 024 | Full ROI

description: FFPE

value: Inv Cancer

value: IIIC

value: Pt 14


title: Pt 6, e11, STIC, stroma, LSP17723_Scan1 | 005 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_051

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_049

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_048

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_050

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_047

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 026 | Full ROI

description: FFPE

value: WT


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 025 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_046

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 027 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 028 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_043

description: Bone marrow biopsy


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 001 | PanCK+

description: FFPE

value: Pt 11


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 002 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_053

description: Bone marrow biopsy

value: Newly diagnosed multiple myeloma


title: Pt 11, e4, STIC, stroma, LSP15340_Scan1 | 001 | PanCK-

description: FFPE

value: high grade serous ovarian carcinoma


title: Newly diagnosed multiple myeloma_042

description: Bone marrow biopsy


title: Pt 11, e4, STIC, stroma, LSP15340_Scan1 | 002 | PanCK-

description: FFPE

value: stroma


title: Newly diagnosed multiple myeloma_041

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_039

description: Bone marrow biopsy


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 003 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_040

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_045

description: Bone marrow biopsy


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 11, e4, STIC, stroma, LSP15340_Scan1 | 003 | PanCK-

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 006 | PanCK+

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 14, e4, FT, epithelial, LSP15360_Scan1 | 029 | Full ROI

description: FFPE

value: FT


title: Newly diagnosed multiple myeloma_035

description: Bone marrow biopsy


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 005 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_038

description: Bone marrow biopsy


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 009 | Full ROI

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 010 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_036

description: Bone marrow biopsy


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 012 | Full ROI

description: FFPE


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 013 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_037

description: Bone marrow biopsy


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 015 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_032

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_033

description: Bone marrow biopsy


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 014 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_030

description: Bone marrow biopsy


title: Pt 11, e4, STIC, epithelial, LSP15340_Scan1 | 016 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_029

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_034

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_028

description: Bone marrow biopsy


title: Pt 11, e4, FT, epithelial, LSP15340_Scan1 | 017 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_024

description: Bone marrow biopsy


title: Pt 11, e4, Inv Cancer, stroma, LSP15340_Scan1 | 010 | PanCK-

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 021 | Full ROI

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 011 | Full ROI

description: FFPE


title: Pt 11, e4, Inv Cancer, epithelial, LSP15340_Scan1 | 022 | Full ROI

description: FFPE


title: Pt 8, e4, STIC, epithelial, LSP15328_Scan1 | 001 | PanCK+

description: FFPE

value: IIA

value: Pt 8


title: Newly diagnosed multiple myeloma_031

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_026

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_025

description: Bone marrow biopsy


title: Pt 8, e4, STIC, epithelial, LSP15328_Scan1 | 002 | PanCK+

description: FFPE

value: epithelial


title: Newly diagnosed multiple myeloma_022

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_027

description: Bone marrow biopsy


title: Pt 8, e4, STIC, epithelial, LSP15328_Scan1 | 003 | PanCK+

description: FFPE

value: STIC


title: Newly diagnosed multiple myeloma_019

description: Bone marrow biopsy


title: Pt 8, e4, Cancer (floating), epithelial, LSP15328_Scan1 | 004 | PanCK+

description: FFPE

value: Cancer (floating)


title: Newly diagnosed multiple myeloma_023

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_017

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_020

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_018

description: Bone marrow biopsy


title: Pt 8, e4, Cancer (floating), epithelial, LSP15328_Scan1 | 005 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_016

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_021

description: Bone marrow biopsy


title: Pt 8, e4, Fimbriae, epithelial, LSP15328_Scan1 | 007 | PanCK+

description: FFPE

value: Fimbriae


title: Pt 8, e4, Fimbriae, epithelial, LSP15328_Scan1 | 008 | PanCK+

description: FFPE


title: Pt 8, e4, Fimbriae, epithelial, LSP15328_Scan1 | 006 | PanCK+

description: FFPE


title: Pt 8, e4, Inv Cancer, epithelial, LSP15328_Scan1 | 011 | PanCK+

description: FFPE


title: Pt 8, e4, Inv Cancer, epithelial, LSP15328_Scan1 | 010 | PanCK+

description: FFPE


title: Pt 8, e4, Cancer (floating), epithelial, LSP15328_Scan1 | 012 | PanCK+

description: FFPE


title: Pt 15, e4, STIC, epithelial, LSP15356_Scan1 | 001 | PanCK+

description: FFPE

value: Pt 15


title: Newly diagnosed multiple myeloma_013

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_014

description: Bone marrow biopsy


title: Pt 15, e4, STIC, epithelial, LSP15356_Scan1 | 003 | PanCK+

description: FFPE


title: Pt 15, e4, STIC, epithelial, LSP15356_Scan1 | 002 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_012

description: Bone marrow biopsy


title: Pt 15, e4, STIC, epithelial, LSP15356_Scan1 | 005 | PanCK+

description: FFPE


title: Pt 15, e4, STIC, epithelial, LSP15356_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 8, e4, Inv Cancer, epithelial, LSP15328_Scan1 | 009 | PanCK+

description: FFPE


title: Newly diagnosed multiple myeloma_011

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_015

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_008

description: Bone marrow biopsy


title: Pt 15, e4, Inv Cancer, epithelial, LSP15356_Scan1 | 007 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_009

description: Bone marrow biopsy


title: Pt 15, e4, Inv Cancer, epithelial, LSP15356_Scan1 | 008 | Full ROI

description: FFPE


title: Newly diagnosed multiple myeloma_010

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_002

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_007

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_005

description: Bone marrow biopsy


title: Smoldering multiple myeloma_122

description: Bone marrow biopsy

value: Smoldering multiple myeloma


title: Smoldering multiple myeloma_120

description: Bone marrow biopsy


title: Smoldering multiple myeloma_119

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_001

description: Bone marrow biopsy


title: Smoldering multiple myeloma_121

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_004

description: Bone marrow biopsy


title: Newly diagnosed multiple myeloma_006

description: Bone marrow biopsy


title: Smoldering multiple myeloma_118

description: Bone marrow biopsy


title: Pt 15, e4, Inv Cancer, epithelial, LSP15356_Scan1 | 009 | Full ROI

description: FFPE

value: Inv Cancer


title: Smoldering multiple myeloma_116

description: Bone marrow biopsy


title: Smoldering multiple myeloma_117

description: Bone marrow biopsy


title: Pt 15, e4, Cancer (floating), epithelial, LSP15356_Scan1 | 010 | Full ROI

description: FFPE

value: IIIC


title: Pt 15, e4, STIC, epithelial, LSP15356_Scan1 | 006 | Full ROI

description: FFPE


title: Pt 12, e4, Inv Cancer, epithelial, LSP15344_Scan1 | 001 | Full ROI

description: FFPE

value: Mut

value: IC

value: Pt 12


title: Pt 15, e4, FT, epithelial, LSP15356_Scan1 | 011 | PanCK+

description: FFPE

value: WT


title: Pt 12, e4, Inv Cancer, epithelial, LSP15344_Scan1 | 003 | Full ROI

description: FFPE

value: high grade serous ovarian carcinoma


title: Pt 12, e4, Inv Cancer, epithelial, LSP15344_Scan1 | 002 | Full ROI

description: FFPE


title: Pt 12, e4, Inv Cancer, epithelial, LSP15344_Scan1 | 005 | Full ROI

description: FFPE


title: Pt 12, e4, Inv Cancer, epithelial, LSP15344_Scan1 | 006 | Full ROI

description: FFPE


title: Pt 12, e4, Cancer (floating), epithelial, LSP15344_Scan1 | 007 | Full ROI

description: FFPE


title: Pt 12, e4, Inv Cancer, epithelial, LSP15344_Scan1 | 004 | Full ROI

description: FFPE


title: Pt 12, e4, STIC, epithelial, LSP15344_Scan1 | 008 | PanCK+

description: FFPE


title: Pt 12, e4, STIC, epithelial, LSP15344_Scan1 | 010 | PanCK+

description: FFPE


title: Pt 12, e4, STIL, epithelial, LSP15344_Scan1 | 011 | PanCK+

description: FFPE

value: STIL


title: Pt 12, e4, STIC, epithelial, LSP15344_Scan1 | 009 | PanCK+

description: FFPE


title: Pt 12, e4, STIL, epithelial, LSP15344_Scan1 | 012 | PanCK+

description: FFPE


title: Pt 12, e4, p53 signature, epithelial, LSP15344_Scan1 | 014 | PanCK+

description: FFPE

value: p53 signature


title: Smoldering multiple myeloma_113

description: Bone marrow biopsy


title: Pt 12, e4, STIL, epithelial, LSP15344_Scan1 | 013 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_115

description: Bone marrow biopsy


title: Smoldering multiple myeloma_111

description: Bone marrow biopsy


title: Pt 12, e4, p53 signature, epithelial, LSP15344_Scan1 | 016 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_105

description: Bone marrow biopsy


title: Smoldering multiple myeloma_114

description: Bone marrow biopsy


title: Smoldering multiple myeloma_109

description: Bone marrow biopsy


title: Smoldering multiple myeloma_110

description: Bone marrow biopsy


title: Smoldering multiple myeloma_108

description: Bone marrow biopsy


title: Smoldering multiple myeloma_112

description: Bone marrow biopsy


title: Pt 12, e4, p53 signature, epithelial, LSP15344_Scan1 | 015 | PanCK+

description: FFPE


title: Pt 10, e4, FT, epithelial, LSP15336_Scan1 | 001 | PanCK+

description: FFPE

value: FT

value: III

value: Pt 10


title: Smoldering multiple myeloma_107

description: Bone marrow biopsy


title: Smoldering multiple myeloma_103

description: Bone marrow biopsy


title: Pt 10, e4, FT, epithelial, LSP15336_Scan1 | 002 | PanCK+

description: FFPE

value: epithelial


title: Smoldering multiple myeloma_104

description: Bone marrow biopsy


title: Pt 10, e4, FT, epithelial, LSP15336_Scan1 | 003 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_102

description: Bone marrow biopsy


title: Pt 10, e4, STIC, epithelial, LSP15336_Scan1 | 004 | PanCK+

description: FFPE

value: STIC


title: Smoldering multiple myeloma_101

description: Bone marrow biopsy


title: Smoldering multiple myeloma_106

description: Bone marrow biopsy


title: Pt 10, e4, STIC, epithelial, LSP15336_Scan1 | 005 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_100

description: Bone marrow biopsy


title: Smoldering multiple myeloma_098

description: Bone marrow biopsy


title: Pt 10, e4, STIC, epithelial, LSP15336_Scan1 | 007 | PanCK+

description: FFPE


title: Pt 10, e4, Cancer (floating), epithelial, LSP15336_Scan1 | 009 | PanCK+

description: FFPE

value: Cancer (floating)


title: Pt 10, e4, Cancer (floating), epithelial, LSP15336_Scan1 | 008 | PanCK+

description: FFPE


title: Pt 10, e4, STIC, epithelial, LSP15336_Scan1 | 006 | PanCK+

description: FFPE


title: Pt 10, e4, Cancer (floating), epithelial, LSP15336_Scan1 | 010 | PanCK+

description: FFPE


title: Pt 10, e4, Inv Cancer, epithelial, LSP15336_Scan1 | 012 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_095

description: Bone marrow biopsy


title: Pt 10, e4, Inv Cancer, epithelial, LSP15336_Scan1 | 013 | PanCK+

description: FFPE


title: Pt 10, e4, p53 signature, epithelial, LSP15336_Scan1 | 014 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_099

description: Bone marrow biopsy


title: Pt 10, e4, p53 signature, epithelial, LSP15336_Scan1 | 015 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_097

description: Bone marrow biopsy


title: Smoldering multiple myeloma_093

description: Bone marrow biopsy


title: Smoldering multiple myeloma_085

description: Bone marrow biopsy


title: Smoldering multiple myeloma_088

description: Bone marrow biopsy


title: Smoldering multiple myeloma_094

description: Bone marrow biopsy


title: Smoldering multiple myeloma_087

description: Bone marrow biopsy


title: Smoldering multiple myeloma_091

description: Bone marrow biopsy


title: Smoldering multiple myeloma_090

description: Bone marrow biopsy


title: Pt 9, e4, STIL, epithelial, LSP15332_Scan1 | 001 | PanCK+

description: FFPE

value: Pt 9


title: Smoldering multiple myeloma_086

description: Bone marrow biopsy

value: Smoldering multiple myeloma


title: Smoldering multiple myeloma_096

description: Bone marrow biopsy


title: Smoldering multiple myeloma_092

description: Bone marrow biopsy


title: Smoldering multiple myeloma_084

description: Bone marrow biopsy


title: Smoldering multiple myeloma_089

description: Bone marrow biopsy


title: Pt 10, e4, Inv Cancer, epithelial, LSP15336_Scan1 | 011 | PanCK+

description: FFPE

value: Inv Cancer


title: Smoldering multiple myeloma_082

description: Bone marrow biopsy


title: Pt 9, e4, STIL, epithelial, LSP15332_Scan1 | 002 | PanCK+

description: FFPE


title: Pt 10, e4, p53 signature, epithelial, LSP15336_Scan1 | 016 | PanCK+

description: FFPE


title: Pt 9, e4, STIL, stroma, LSP15332_Scan1 | 003 | PanCK-

description: FFPE

value: stroma


title: Pt 9, e4, STIL, stroma, LSP15332_Scan1 | 002 | PanCK-

description: FFPE

value: Mut


title: Pt 9, e4, STIL, epithelial, LSP15332_Scan1 | 003 | PanCK+

description: FFPE

value: IC


title: Pt 9, e4, STIL, stroma, LSP15332_Scan1 | 001 | PanCK-

description: FFPE


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 004 | PanCK+

description: FFPE


title: Pt 9, e4, STIC, stroma, LSP15332_Scan1 | 004 | PanCK-

description: FFPE


title: Pt 9, e4, STIC, stroma, LSP15332_Scan1 | 005 | PanCK-

description: FFPE


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 006 | PanCK+

description: FFPE


title: Pt 9, e4, STIC, stroma, LSP15332_Scan1 | 007 | PanCK-

description: FFPE


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 008 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_073

description: Bone marrow biopsy


title: Smoldering multiple myeloma_078

description: Bone marrow biopsy


title: Smoldering multiple myeloma_077

description: Bone marrow biopsy


title: Pt 9, e4, STIC, stroma, LSP15332_Scan1 | 008 | PanCK-

description: FFPE


title: Smoldering multiple myeloma_081

description: Bone marrow biopsy


title: Smoldering multiple myeloma_069

description: Bone marrow biopsy


title: Smoldering multiple myeloma_066

description: Bone marrow biopsy


title: Smoldering multiple myeloma_080

description: Bone marrow biopsy


title: Smoldering multiple myeloma_070

description: Bone marrow biopsy


title: Smoldering multiple myeloma_072

description: Bone marrow biopsy


title: Smoldering multiple myeloma_074

description: Bone marrow biopsy


title: Smoldering multiple myeloma_083

description: Bone marrow biopsy


title: Smoldering multiple myeloma_075

description: Bone marrow biopsy


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 005 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_079

description: Bone marrow biopsy


title: Smoldering multiple myeloma_068

description: Bone marrow biopsy


title: Smoldering multiple myeloma_071

description: Bone marrow biopsy


title: Smoldering multiple myeloma_065

description: Bone marrow biopsy


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 007 | PanCK+

description: FFPE


title: Pt 9, e4, Inv Cancer, epithelial, LSP15332_Scan1 | 010 | PanCK+

description: FFPE


title: Pt 9, e4, Inv Cancer, stroma, LSP15332_Scan1 | 010 | PanCK-

description: FFPE


title: Smoldering multiple myeloma_064

description: Bone marrow biopsy


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 009 | PanCK+

description: FFPE


title: Pt 9, e4, STIC, stroma, LSP15332_Scan1 | 006 | PanCK-

description: FFPE


title: Pt 9, e4, STIC, stroma, LSP15332_Scan1 | 009 | PanCK-

description: FFPE


title: Pt 9, e4, Inv Cancer, epithelial, LSP15332_Scan1 | 011 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_067

description: Bone marrow biopsy


title: Smoldering multiple myeloma_063

description: Bone marrow biopsy


title: Smoldering multiple myeloma_062

description: Bone marrow biopsy


title: Smoldering multiple myeloma_060

description: Bone marrow biopsy


title: Pt 9, e4, Inv Cancer, stroma, LSP15332_Scan1 | 011 | PanCK-

description: FFPE


title: Smoldering multiple myeloma_061

description: Bone marrow biopsy


title: Pt 9, e4, Inv Cancer, epithelial, LSP15332_Scan1 | 012 | PanCK+

description: FFPE


title: Pt 9, e4, Inv Cancer, stroma, LSP15332_Scan1 | 012 | PanCK-

description: FFPE


title: Smoldering multiple myeloma_059

description: Bone marrow biopsy


title: Pt 9, e4, p53 signature, epithelial, LSP15332_Scan1 | 014 | PanCK+

description: FFPE


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 016 | PanCK+

description: FFPE


title: Pt 9, e4, p53 signature, epithelial, LSP15332_Scan1 | 015 | PanCK+

description: FFPE


title: Pt 9, e4, STIC, epithelial, LSP15332_Scan1 | 017 | PanCK+

description: FFPE


title: Pt 9, e4, Inv Cancer, epithelial, LSP15332_Scan1 | 018 | PanCK+

description: FFPE


title: Pt 9, e4, Inv Cancer, epithelial, LSP15332_Scan1 | 020 | Full ROI

description: FFPE


title: Pt 9, e4, Cancer (floating), epithelial, LSP15332_Scan1 | 021 | PanCK+

description: FFPE


title: Pt 9, e4, p53 signature, epithelial, LSP15332_Scan1 | 013 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_058

description: Bone marrow biopsy


title: Pt 9, e4, FT, epithelial, LSP15332_Scan1 | 022 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_054

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 001 | PanCK-

description: FFPE

value: IIIB

value: Pt 13


title: Smoldering multiple myeloma_048

description: Bone marrow biopsy


title: Smoldering multiple myeloma_047

description: Bone marrow biopsy


title: Pt 9, e4, Inv Cancer, epithelial, LSP15332_Scan1 | 019 | Full ROI

description: FFPE

value: high grade serous ovarian carcinoma


title: Smoldering multiple myeloma_046

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 002 | PanCK+

description: FFPE

value: WT


title: Smoldering multiple myeloma_050

description: Bone marrow biopsy


title: Smoldering multiple myeloma_055

description: Bone marrow biopsy


title: Smoldering multiple myeloma_057

description: Bone marrow biopsy


title: Smoldering multiple myeloma_049

description: Bone marrow biopsy


title: Smoldering multiple myeloma_045

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 003 | PanCK+

description: FFPE


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 003 | PanCK-

description: FFPE


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 002 | PanCK-

description: FFPE


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 004 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_051

description: Bone marrow biopsy


title: Smoldering multiple myeloma_052

description: Bone marrow biopsy


title: Smoldering multiple myeloma_053

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 004 | PanCK-

description: FFPE


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 001 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_042

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 005 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_039

description: Bone marrow biopsy


title: Smoldering multiple myeloma_043

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 005 | PanCK-

description: FFPE


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 006 | PanCK+

description: FFPE


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 006 | PanCK-

description: FFPE


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 007 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_038

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 007 | PanCK-

description: FFPE


title: Smoldering multiple myeloma_044

description: Bone marrow biopsy


title: Smoldering multiple myeloma_040

description: Bone marrow biopsy


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 009 | PanCK+

description: FFPE


title: Smoldering multiple myeloma_037

description: Bone marrow biopsy


title: Smoldering multiple myeloma_036

description: Bone marrow biopsy


title: Smoldering multiple myeloma_041

description: Bone marrow biopsy


title: Pt 13, e4, Fimbriae, epithelial, LSP15348_Scan1 | 008 | Full ROI

description: FFPE

value: Fimbriae


title: Smoldering multiple myeloma_035

description: Bone marrow biopsy


title: Smoldering multiple myeloma_034

description: Bone marrow biopsy


title: Pt 13, e4, Fimbriae, epithelial, LSP15348_Scan1 | 010 | Full ROI

description: FFPE


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 009 | PanCK-

description: FFPE


title: Pt 13, e4, Inv Cancer, epithelial, LSP15348_Scan1 | 011 | PanCK+

description: FFPE


title: Pt 13, e4, Inv Cancer, stroma, LSP15348_Scan1 | 011 | PanCK-

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 001 | Full ROI

description: FFPE

value: IIIC

value: Pt 14


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 002 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_031

description: Bone marrow biopsy


title: Smoldering multiple myeloma_033

description: Bone marrow biopsy


title: Smoldering multiple myeloma_029

description: Bone marrow biopsy


title: Smoldering multiple myeloma_032

description: Bone marrow biopsy


title: Smoldering multiple myeloma_030

description: Bone marrow biopsy


title: Smoldering multiple myeloma_028

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 005 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_025

description: Bone marrow biopsy


title: Smoldering multiple myeloma_026

description: Bone marrow biopsy


title: Smoldering multiple myeloma_023

description: Bone marrow biopsy


title: Smoldering multiple myeloma_024

description: Bone marrow biopsy


title: Smoldering multiple myeloma_027

description: Bone marrow biopsy


title: Smoldering multiple myeloma_022

description: Bone marrow biopsy


title: Pt 14, e4, STIC, epithelial, LSP15360_Scan1 | 008 | Full ROI

description: FFPE


title: Pt 14, e4, p53 signature, epithelial, LSP15360_Scan1 | 007 | Full ROI

description: FFPE

value: p53 signature


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 006 | Full ROI

description: FFPE

value: epithelial


title: Pt 14, e4, STIC, epithelial, LSP15360_Scan1 | 009 | Full ROI

description: FFPE

value: STIC


title: Pt 14, e4, STIC, epithelial, LSP15360_Scan1 | 010 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 012 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 003 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 011 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_021

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 013 | Full ROI

description: FFPE


title: Pt 14, e4, FT, epithelial, LSP15360_Scan1 | 014 | Full ROI

description: FFPE

value: FT


title: Smoldering multiple myeloma_019

description: Bone marrow biopsy


title: Smoldering multiple myeloma_017

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 015 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 017 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 018 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_018

description: Bone marrow biopsy


title: Smoldering multiple myeloma_020

description: Bone marrow biopsy


title: Smoldering multiple myeloma_016

description: Bone marrow biopsy


title: Smoldering multiple myeloma_014

description: Bone marrow biopsy


title: Smoldering multiple myeloma_012

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 016 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_015

description: Bone marrow biopsy


title: Smoldering multiple myeloma_013

description: Bone marrow biopsy


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 019 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, stroma, LSP15360_Scan1 | 020 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 022 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 021 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_010

description: Bone marrow biopsy


title: Pt 16, e6, FT, epithelial, LSP16139_Scan2 | 001 | Full ROI

description: FFPE

value: III

value: Pt 16


title: Smoldering multiple myeloma_009

description: Bone marrow biopsy

value: Smoldering multiple myeloma


title: Pt 16, e6, FT, epithelial, LSP16139_Scan2 | 002 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_008

description: Bone marrow biopsy


title: Pt 16, e6, FT, epithelial, LSP16139_Scan2 | 003 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_011

description: Bone marrow biopsy


title: Pt 16, e6, Fimbriae, epithelial, LSP16139_Scan2 | 004 | Full ROI

description: FFPE


title: Pt 16, e6, Fimbriae, epithelial, LSP16139_Scan2 | 005 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_005

description: Bone marrow biopsy


title: Pt 16, e6, Cancer (floating), epithelial, LSP16139_Scan2 | 008 | Full ROI

description: FFPE

value: Cancer (floating)


title: Pt 16, e6, Fimbriae, epithelial, LSP16139_Scan2 | 006 | Full ROI

description: FFPE


title: Smoldering multiple myeloma_004

description: Bone marrow biopsy


title: Smoldering multiple myeloma_002

description: Bone marrow biopsy


title: Pt 16, e6, Cancer (floating), epithelial, LSP16139_Scan2 | 009 | Full ROI

description: FFPE


title: Pt 16, e6, Fimbriae, epithelial, LSP16139_Scan2 | 012 | Full ROI

description: FFPE


title: Pt 16, e6, Fimbriae, epithelial, LSP16139_Scan2 | 011 | Full ROI

description: FFPE


title: Pt 16, e6, Fimbriae, epithelial, LSP16139_Scan2 | 010 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_117

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_119

description: Bone marrow biopsy


title: Smoldering multiple myeloma_001

description: Bone marrow biopsy


title: Smoldering multiple myeloma_003

description: Bone marrow biopsy


title: Smoldering multiple myeloma_006

description: Bone marrow biopsy


title: Smoldering multiple myeloma_007

description: Bone marrow biopsy


title: Pt 16, e6, Inv Cancer, epithelial, LSP16139_Scan2 | 013 | Full ROI

description: FFPE

value: Inv Cancer


title: Monoclonal gammopathy of undetermined significance_120

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_121

description: Bone marrow biopsy


title: Pt 16, e6, Cancer (floating), epithelial, LSP16139_Scan2 | 007 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_116

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_122

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_118

description: Bone marrow biopsy


title: Pt 16, e6, Inv Cancer, epithelial, LSP16139_Scan2 | 014 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_115

description: Bone marrow biopsy


title: Pt 16, e6, Inv Cancer, epithelial, LSP16139_Scan2 | 015 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_114

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_113

description: Bone marrow biopsy


title: Pt 16, e6, Inv Cancer, epithelial, LSP16139_Scan2 | 016 | Full ROI

description: FFPE


title: Pt 16, e6, Inv Cancer, epithelial, LSP16139_Scan2 | 017 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_112

description: Bone marrow biopsy


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 019 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_111

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_110

description: Bone marrow biopsy


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 021 | Full ROI

description: FFPE


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 022 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_109

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_108

description: Bone marrow biopsy


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 024 | Full ROI

description: FFPE


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 023 | Full ROI

description: FFPE


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 026 | Full ROI

description: FFPE


title: Pt 16, e6, Inv Cancer, epithelial, LSP16139_Scan2 | 018 | Full ROI

description: FFPE


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 001 | Full ROI

description: FFPE

value: Pt 17


title: Monoclonal gammopathy of undetermined significance_105

description: Bone marrow biopsy


title: Pt 16, e6, Cancer (floating), stroma, LSP16139_Scan2 | 027 | Full ROI

description: FFPE

value: stroma


title: Monoclonal gammopathy of undetermined significance_106

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_104

description: Bone marrow biopsy


title: Pt 17, e6, STIC, stroma, LSP16142_Scan2 | 002 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_107

description: Bone marrow biopsy


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 020 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_102

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_103

description: Bone marrow biopsy


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 003 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_101

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_098

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_100

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_099

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_097

description: Bone marrow biopsy


title: Pt 16, e6, STIC, epithelial, LSP16139_Scan2 | 025 | Full ROI

description: FFPE


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 004 | Full ROI

description: FFPE


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 006 | Full ROI

description: FFPE


title: Pt 17, e6, p53 signature, epithelial, LSP16142_Scan2 | 007 | Full ROI

description: FFPE


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 005 | Full ROI

description: FFPE


title: Pt 14, e4, Inv Cancer, epithelial, LSP15360_Scan1 | 004 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_092

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_093

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_095

description: Bone marrow biopsy


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 011 | Full ROI

description: FFPE


title: Pt 17, e6, p53 signature, epithelial, LSP16142_Scan2 | 008 | Full ROI

description: FFPE


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 012 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_094

description: Bone marrow biopsy


title: Pt 17, e6, STIC, stroma, LSP16142_Scan2 | 010 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_096

description: Bone marrow biopsy


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 015 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_090

description: Bone marrow biopsy


title: Pt 17, e6, STIC, epithelial, LSP16142_Scan2 | 016 | Full ROI

description: FFPE


title: Pt 17, e6, STIC, stroma, LSP16142_Scan2 | 013 | Full ROI

description: FFPE


title: Pt 18, e6, FT, epithelial, LSP16145_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 18


title: Pt 17, e6, p53 signature, epithelial, LSP16142_Scan2 | 009 | Full ROI

description: FFPE

value: high grade serous ovarian carcinoma


title: Pt 17, e6, STIC, stroma, LSP16142_Scan2 | 018 | Full ROI

description: FFPE

value: WT


title: Pt 18, e6, FT, epithelial, LSP16145_Scan1 | 002 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_088

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_089

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_087

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_085

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_084

description: Bone marrow biopsy


title: Pt 18, e6, FT, epithelial, LSP16145_Scan1 | 003 | Full ROI

description: FFPE


title: Pt 18, e6, Fimbriae, epithelial, LSP16145_Scan1 | 004 | Full ROI

description: FFPE

value: Fimbriae


title: Monoclonal gammopathy of undetermined significance_080

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_082

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_081

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_083

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_086

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_091

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_079

description: Bone marrow biopsy


title: Pt 17, e6, STIC, stroma, LSP16142_Scan2 | 014 | Full ROI

description: FFPE


title: Pt 18, e6, Fimbriae, epithelial, LSP16145_Scan1 | 005 | Full ROI

description: FFPE


title: Pt 18, e6, Fimbriae, epithelial, LSP16145_Scan1 | 006 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_078

description: Bone marrow biopsy


title: Pt 18, e6, Inv Cancer, epithelial, LSP16145_Scan1 | 013 | Full ROI

description: FFPE


title: Pt 18, e6, Inv Cancer, epithelial, LSP16145_Scan1 | 011 | Full ROI

description: FFPE


title: Pt 18, e6, Inv Cancer, epithelial, LSP16145_Scan1 | 014 | Full ROI

description: FFPE


title: Pt 18, e6, Inv Cancer, epithelial, LSP16145_Scan1 | 015 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_077

description: Bone marrow biopsy


title: Pt 18, e6, STIC, epithelial, LSP16145_Scan1 | 020 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_073

description: Bone marrow biopsy


title: Pt 18, e6, STIC, epithelial, LSP16145_Scan1 | 021 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_075

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_076

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_074

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_071

description: Bone marrow biopsy


title: Pt 18, e6, STIC, stroma, LSP16145_Scan1 | 022 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_070

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_072

description: Bone marrow biopsy


title: Pt 18, e6, STIC, epithelial, LSP16145_Scan1 | 024 | Full ROI

description: FFPE


title: Pt 19, e6, STIC, epithelial, LSP16148_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 19


title: Pt 18, e6, STIC, epithelial, LSP16145_Scan1 | 025 | Full ROI

description: FFPE


title: Pt 19, e6, STIC, epithelial, LSP16148_Scan1 | 002 | Full ROI

description: FFPE


title: Pt 18, e6, STIC, epithelial, LSP16145_Scan1 | 026 | Full ROI

description: FFPE


title: Pt 19, e6, Inv Cancer, epithelial, LSP16148_Scan1 | 004 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_069

description: Bone marrow biopsy


title: Pt 19, e6, STIC, epithelial, LSP16148_Scan1 | 003 | Full ROI

description: FFPE


title: Pt 19, e6, Inv Cancer, epithelial, LSP16148_Scan1 | 005 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_067

description: Bone marrow biopsy


title: Pt 18, e6, STIC, epithelial, LSP16145_Scan1 | 023 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_063

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_064

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_066

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_065

description: Bone marrow biopsy


title: Pt 19, e6, Inv Cancer, epithelial, LSP16148_Scan1 | 007 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_062

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_061

description: Bone marrow biopsy


title: Pt 19, e6, Inv Cancer, epithelial, LSP16148_Scan1 | 009 | Full ROI

description: FFPE


title: Pt 19, e6, Inv Cancer, epithelial, LSP16148_Scan1 | 008 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_060

description: Bone marrow biopsy


title: Pt 20, e6, STIC, epithelial, LSP16151_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 20


title: Pt 20, e6, STIC, epithelial, LSP16151_Scan1 | 002 | Full ROI

description: FFPE


title: Pt 19, e6, Inv Cancer, epithelial, LSP16148_Scan1 | 006 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_058

description: Bone marrow biopsy


title: Pt 20, e6, STIC, epithelial, LSP16151_Scan1 | 004 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_056

description: Bone marrow biopsy


title: Pt 20, e6, STIC, epithelial, LSP16151_Scan1 | 003 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_057

description: Bone marrow biopsy


title: Pt 20, e6, STIC, epithelial, LSP16151_Scan1 | 005 | Full ROI

description: FFPE


title: Pt 20, e6, STIL, epithelial, LSP16151_Scan1 | 006 | Full ROI

description: FFPE

value: STIL


title: Pt 20, e6, p53 signature, epithelial, LSP16151_Scan1 | 007 | Full ROI

description: FFPE

value: epithelial

value: p53 signature


title: Monoclonal gammopathy of undetermined significance_059

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_055

description: Bone marrow biopsy


title: Pt 21, e6, Inv Cancer, epithelial, LSP16154_Scan2 | 001 | PanCK+

description: FFPE

value: Mut

value: Pt 21


title: Monoclonal gammopathy of undetermined significance_053

description: Bone marrow biopsy


title: Pt 21, e6, Inv Cancer, stroma, LSP16154_Scan2 | 001 | PanCK-

description: FFPE

value: III


title: Pt 20, e6, STIC, epithelial, LSP16151_Scan1 | 008 | Full ROI

description: FFPE

value: STIC


title: Monoclonal gammopathy of undetermined significance_052

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_051

description: Bone marrow biopsy


title: Pt 21, e6, Inv Cancer, stroma, LSP16154_Scan2 | 002 | PanCK-

description: FFPE


title: Monoclonal gammopathy of undetermined significance_050

description: Bone marrow biopsy


title: Pt 21, e6, Inv Cancer, epithelial, LSP16154_Scan2 | 002 | PanCK+

description: FFPE


title: Pt 21, e6, Inv Cancer, epithelial, LSP16154_Scan2 | 003 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_054

description: Bone marrow biopsy


title: Pt 21, e6, FT, epithelial, LSP16154_Scan2 | 005 | Full ROI

description: FFPE

value: FT


title: Pt 21, e6, FT, epithelial, LSP16154_Scan2 | 004 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_049

description: Bone marrow biopsy


title: Pt 21, e6, FT, epithelial, LSP16154_Scan2 | 007 | Full ROI

description: FFPE


title: Pt 21, e6, FT, epithelial, LSP16154_Scan2 | 008 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_046

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_042

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_044

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_041

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_068

description: Bone marrow biopsy


title: Pt 21, e6, FT, epithelial, LSP16154_Scan2 | 009 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_037

description: Bone marrow biopsy


title: Pt 21, e6, Fimbriae, epithelial, LSP16154_Scan2 | 010 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_036

description: Bone marrow biopsy


title: Pt 21, e6, FT, epithelial, LSP16154_Scan2 | 006 | Full ROI

description: FFPE


title: Pt 21, e6, Inv Cancer, stroma, LSP16154_Scan2 | 013 | Full ROI

description: FFPE

value: Inv Cancer


title: Pt 21, e6, Fimbriae, epithelial, LSP16154_Scan2 | 012 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_040

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_048

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_045

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_038

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_047

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_035

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_034

description: Bone marrow biopsy


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 001 | Full ROI

description: FFPE

value: Pt 22


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 002 | Full ROI

description: FFPE

value: stroma


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 003 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_039

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_029

description: Bone marrow biopsy


title: Pt 21, e6, Fimbriae, epithelial, LSP16154_Scan2 | 011 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_032

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_030

description: Bone marrow biopsy


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 006 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_028

description: Bone marrow biopsy


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 007 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_027

description: Bone marrow biopsy


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 005 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 008 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_026

description: Bone marrow biopsy


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 009 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_031

description: Bone marrow biopsy


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 013 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 015 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 011 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_025

description: Bone marrow biopsy


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 014 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 010 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 016 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 004 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_022

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_021

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_024

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_019

description: Bone marrow biopsy


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 018 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 017 | Full ROI

description: FFPE


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 019 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_015

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_017

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_023

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_016

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_018

description: Bone marrow biopsy


title: Pt 22, e6, STIC, epithelial, LSP16157_Scan1 | 020 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_020

description: Bone marrow biopsy


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 021 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_013

description: Bone marrow biopsy


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 025 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, stroma, LSP16157_Scan1 | 024 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 026 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, stroma, LSP16157_Scan1 | 022 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_014

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_012

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_010

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_008

description: Bone marrow biopsy


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 027 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_009

description: Bone marrow biopsy


title: Pt 22, e6, Inv Cancer, stroma, LSP16157_Scan1 | 030 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, stroma, LSP16157_Scan1 | 028 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 023 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_006

description: Bone marrow biopsy


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 033 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 034 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 029 | Full ROI

description: FFPE


title: Pt 22, e6, Inv Cancer, epithelial, LSP16157_Scan1 | 031 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_005

description: Bone marrow biopsy


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 001 | Full ROI

description: FFPE

value: Pt 11


title: Pt 22, e6, STIC, stroma, LSP16157_Scan1 | 035 | Full ROI

description: FFPE

value: high grade serous ovarian carcinoma


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 002 | Full ROI

description: FFPE

value: WT


title: Monoclonal gammopathy of undetermined significance_001

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_002

description: Bone marrow biopsy


title: Pt 22, e6, Inv Cancer, stroma, LSP16157_Scan1 | 032 | Full ROI

description: FFPE


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 003 | Full ROI

description: FFPE


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 004 | Full ROI

description: FFPE


title: Monoclonal gammopathy of undetermined significance_004

description: Bone marrow biopsy


title: Healthy donor_067

description: Bone marrow biopsy

value: Healthy donor


title: Healthy donor_065

description: Bone marrow biopsy


title: Healthy donor_066

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_007

description: Bone marrow biopsy


title: Healthy donor_064

description: Bone marrow biopsy


title: Healthy donor_061

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_011

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_003

description: Bone marrow biopsy


title: Healthy donor_063

description: Bone marrow biopsy


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 005 | Full ROI

description: FFPE


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 006 | Full ROI

description: FFPE


title: Pt 11, e6, Inv Cancer, stroma, LSP16160_Scan2 | 007 | PanCK-

description: FFPE


title: Pt 11, e6, Inv Cancer, stroma, LSP16160_Scan2 | 008 | PanCK-

description: FFPE


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 008 | PanCK+

description: FFPE


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 009 | Full ROI

description: FFPE


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 010 | Full ROI

description: FFPE


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 012 | Full ROI

description: FFPE


title: Pt 11, e6, Inv Cancer, epithelial, LSP16160_Scan2 | 007 | PanCK+

description: FFPE


title: Healthy donor_060

description: Bone marrow biopsy


title: Healthy donor_057

description: Bone marrow biopsy


title: Healthy donor_058

description: Bone marrow biopsy


title: Monoclonal gammopathy of undetermined significance_033

description: Bone marrow biopsy


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 013 | Full ROI

description: FFPE


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 014 | Full ROI

description: FFPE


title: Healthy donor_056

description: Bone marrow biopsy


title: Healthy donor_054

description: Bone marrow biopsy


title: Healthy donor_062

description: Bone marrow biopsy


title: Healthy donor_052

description: Bone marrow biopsy


title: Healthy donor_055

description: Bone marrow biopsy


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 016 | Full ROI

description: FFPE


title: Healthy donor_050

description: Bone marrow biopsy


title: Pt 11, e6, Cancer (floating), epithelial, LSP16160_Scan2 | 015 | Full ROI

description: FFPE

value: Cancer (floating)


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 017 | Full ROI

description: FFPE


title: Pt 11, e6, STIC, epithelial, LSP16160_Scan2 | 011 | Full ROI

description: FFPE


title: Healthy donor_051

description: Bone marrow biopsy


title: Healthy donor_053

description: Bone marrow biopsy


title: Pt 11, e6, Cancer (floating), epithelial, LSP16160_Scan2 | 018 | Full ROI

description: FFPE


title: Pt 11, e6, FT, epithelial, LSP16160_Scan2 | 020 | Full ROI

description: FFPE


title: Pt 11, e6, FT, epithelial, LSP16160_Scan2 | 019 | Full ROI

description: FFPE


title: Healthy donor_047

description: Bone marrow biopsy


title: Pt 11, e6, Inv Cancer, stroma, LSP16160_Scan2 | 022 | Full ROI

description: FFPE


title: Pt 11, e6, Inv Cancer, stroma, LSP16160_Scan2 | 023 | Full ROI

description: FFPE


title: Healthy donor_049

description: Bone marrow biopsy


title: Healthy donor_045

description: Bone marrow biopsy


title: Healthy donor_048

description: Bone marrow biopsy


title: Healthy donor_044

description: Bone marrow biopsy


title: Healthy donor_046

description: Bone marrow biopsy


title: Healthy donor_042

description: Bone marrow biopsy


title: Pt 11, e6, Inv Cancer, stroma, LSP16160_Scan2 | 024 | Full ROI

description: FFPE


title: Healthy donor_043

description: Bone marrow biopsy


title: 2421_180327_T1_TMZ_HTO

city: New York

first: Mungunsarnai

last: Ganbold

state: NYC

address: 417 East 68st

department: Brain Tumor Center

institute: MSKCC

description:
T1 TMZ samples 1-3, single cell transcriptomics
TMZ treated T1 PDX, HTO,  biological samples 1- 3  multiplexed in one library

library_source: other

data_processing:
Raw reads were aligned to GRCh38 human reference genome in a Linux environment using STAR (v.2.7.8a) and gene-level counts were generated with “quantMode GeneCounts" parameter.
Assembly: GRCh38
Supplementary files format and content: FASTQ PE  raw files, some multiplexed, with HTO
Supplementary files format and content: Single cell processed files come as RDS Seurat objects, bulkRNA seq - as comma-separated gene level counts
Library strategy: HTO

molecule: protein

source_name: primary cells

growth_protocol: PDX primary cells. See STAR Methods, Xiex et al., 2024

extract_protocol:
PDX tumor samples were collected directly into Trizol LS reagent (Invitrogen 10296028) and submitted to Integrated Genomics Operation facility (MSKCC) for RNA extraction, followed by poly(A) selection, and subsequent Illumina TruSeq paired-end library preparation according to the manufacturer’s protocols. Sequencing was performed on the Illumina HiSeq 2500 to a depth of 30–50 million 50-bp read pairs per sample.
Single cell libraries constructed in IGO, MSKCC with a standart 10X Chromium library kits. Bulk RNAseq - with Illumina TruSeq.

treatment_protocol: Temozolomide treatment for 5 days. See STAR Methods, Xiex et al., 2024

value: human PDX

tag: cell line

value: primary cells

tag: treatment

value: TMZ


title: 2450_180327_DMSO

description:
T1 DMSO samples 1-3, single cell transcriptomics
DMSO T1 PDX, GEX, biological samples 1-4 (3used)  multiplexed in one library

library_source: transcriptomic single cell

data_processing:
Raw reads were aligned to GRCh38 human reference genome in a Linux environment using STAR (v.2.7.8a) and gene-level counts were generated with “quantMode GeneCounts" parameter.
Assembly: GRCh38
Supplementary files format and content: FASTQ PE  raw files, some multiplexed, with HTO
Supplementary files format and content: Single cell processed files come as RDS Seurat objects, bulkRNA seq - as comma-separated gene level counts

molecule: polyA RNA

value: DMSO


title: 2421_180327_T1_TMZ

description:
T1 TMZ samples 1-3, single cell transcriptomics
TMZ treated T1 PDX, GEX,  biological samples 1- 3  multiplexed in one library


title: 2450_180327_DMSO_HTO

description:
T1 DMSO samples 1-3, single cell transcriptomics
DMSO T1 PDX, HTO, biological samples 1-4  (3used)  multiplexed in one library


title: Pt 11, e6, FT, epithelial, LSP16160_Scan2 | 021 | Full ROI

description: FFPE

value: epithelial


title: Healthy donor_037

description: Bone marrow biopsy


title: 4345_XX-2001_160811-1_P10_1-4

description:
T13 Primary samples 3-6 (one is not used), single cell transcriptomics
Primary T12 PDX, GEX, biological samples 1-4 (3used) multiplexed in one library


title: Healthy donor_041

description: Bone marrow biopsy


title: Healthy donor_040

description: Bone marrow biopsy


title: Healthy donor_039

description: Bone marrow biopsy


title: Healthy donor_038

description: Bone marrow biopsy


title: 2227_160811_5

description:
T13 Primary sample 2, single cell transcriptomics
Primary T12 PDX biological samples  2


title: Healthy donor_035

description: Bone marrow biopsy


title: Healthy donor_036

description: Bone marrow biopsy


title: 4345_XX-2001_160811-1_P10_1-4_HTO

description:
T13 Primary samples 3-6 (one is not used), single cell transcriptomics
Primary T12 PDX, HTO, biological samples 1-4 (3used) multiplexed in one library


title: 2226_160811_2

description:
T13 Primary sample 1, single cell transcriptomics
Primary T12 PDX biological samples 1


title: Healthy donor_034

description: Bone marrow biopsy


title: Healthy donor_033

description: Bone marrow biopsy


title: Healthy donor_032

description: Bone marrow biopsy


title: 2283_171003_MIX_HTO

description:
T13 Recurrent (primary-matching) samples 1-4, single cell transcriptomics
Recurrent T12 PDX, HTO, biological samples 1-4  multiplexed in one library


title: Healthy donor_030

description: Bone marrow biopsy


title: Healthy donor_031

description: Bone marrow biopsy


title: 2283_171003_MIX

description:
T13 Recurrent (primary-matching) samples 1-4, single cell transcriptomics
Recurrent T12 PDX,GEX, biological samples 1-4  multiplexed in one library


title: 3752_XX-1659_032522_180327-1-P10_HTO

description:
T1 Passage-10 samples 1-4, HTO, single cell transcriptomics
T1 PDX passage 10, HTO, biological samples 1-4 multiplexed in one library


title: 180327-I-PO-I_2

description:
T1 Passage-0 sample 2, single cell transcriptomics
T1 tumor PDX passage 0 biological sample 2


title: 3752_XX-1659_032522_180327-1-P10

description:
T1 Passage-10 GEX for samples 1-4, single cell transcriptomics
T1 PDX passage 10, GEX, biological samples 1-4 multiplexed in one library


title: 180327-I-PO-I_freeze

description:
T1 Passage-0 sample 3, single cell transcriptomics
T1 tumor PDX passage 0 biological sample 3


title: 180327-I-PO-I

description:
T1 Passage-0 sample 1, single cell transcriptomics
T1 tumor PDX passage 0 biological sample 1


title: RANKL_24h

first: Takayuki

last: Fujii

state: NY

address: 515 E 71st St

institute: Hospital for Special Surgery

data_processing:
Reads were mapped and reads in exons were counted to the human genome (Hg38) using CellRanger v3.0.
Assembly: GRCh38
Supplementary files format and content: .h5

source_name: CD14+ cells

growth_protocol: Human CD14+ cells were harvested from the blood and treated with MCSF

extract_protocol:
10x Genomics Chromium Controller on the single cell suspension
Chromium Next GEM Single Cell 3ʹ Reagent Kits v3.1

treatment_protocol: Human CD14+ cells treated with RANKL for 6 hours and 24 hours

value: CD14+ cells

value: RANKL


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - H3K27ac immunoprecipitation

city: Aurora

first: John

last: DeSisto

state: CO

department: Pediatrics

institute: University of Colorado

description:
GBM1 P612 H3K27ac
230516 GBM1 H3K27ac PRMT5_merged vs SHC202, all unique_peaks with values.csv

library_source: genomic

data_processing:
Alignment to GrCh38 (Bowtie)
Peak calling (MACS3)
Peak analysis (DiffBind, ChIPpeakAnno)
Assembly: GrCh38
Supplementary files format and content: csv;for signalValue > 0, feature_1 and feature_2 are PRMT5 KD peaks, signalValue is the average of signalValue_1 and signalValue_2; for signalValue < 0, signalValue is SHC202 peaks.

molecule: genomic DNA

source_name: cerebral cortex

growth_protocol: Pediatric high grade glioma cells (DMG and cortical) were cultured in suspension

extract_protocol:
Approximately 5-10 million cells were fixed in 1% formaldehyde, after which cells were lysed. Nuclei were sonicated at low energy to fully isolate them from the cytosol. Nuclei were then sonicated at high energy in a Bioruptor Plus (Diagenode) to yield DNA fragments of 200-600 bp.
Sequencing libraries of genomic DNA were prepared using the TruSeq Library Preparation Kit v2 (Agilent)

treatment_protocol: Individual cultures were lentivirally transduced with empty vector control shRNA (SHC202) or a PRMT5 targeting shRNA ((TRCN0000379612, TRCN0000303446, or TRCN0000381130))

value: cerebral cortex

value: Pediatric high grade glioma

tag: antibody

value: PRMT5 knockdown


title: Healthy donor_026

description: Bone marrow biopsy


title: Healthy donor_028

description: Bone marrow biopsy


title: RANKL_6h


title: Healthy donor_027

description: Bone marrow biopsy


title: GBM1 cells transduced with control shRNA SHC202 - H3K27ac immunoprecipitation

description:
GBM1 SHC202 H3K27ac
230516 GBM1 H3K27ac PRMT5_merged vs SHC202, all unique_peaks with values.csv

value: control


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 - H3K27ac immunoprecipitation

description:
GBM1 P446 H3K27ac
230516 GBM1 H3K27ac PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - H3K27ac immunoprecipitation

description:
BT245 P446 H3K27ac
230516 BT245 H3K27ac PRMT5_merged vs SHC202, all unique_peaks with values.csv

source_name: thalamus

value: thalamus

value: Diffuse midline glioma


title: Healthy donor_029

description: Bone marrow biopsy


title: Healthy donor_023

description: Bone marrow biopsy


title: Healthy donor_025

description: Bone marrow biopsy


title: Healthy donor_020

description: Bone marrow biopsy


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - H3K27ac immunoprecipitation

description:
BT245 P130 H3K27ac
230516 BT245 H3K27ac PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: Healthy donor_024

description: Bone marrow biopsy


title: BT245 cells transduced with control shRNA SHC202 - H3K27ac immunoprecipitation

description:
BT245 SHC202 H3K27ac
230516 BT245 H3K27ac PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 - H3K27me3 immunoprecipitation

description:
GBM1 P446 H3K27me3
230516 GBM1 H3K27me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with control shRNA SHC202 - H3K27me3 immunoprecipitation

description:
GBM1 SHC202 H3K27me3
230516 GBM1 H3K27me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: Healthy donor_021

description: Bone marrow biopsy


title: Healthy donor_022

description: Bone marrow biopsy


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - H3K27me3 immunoprecipitation

description:
BT245 P130 H3K27me3
230516 BT245 H3K27me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: BT245 cells transduced with control shRNA SHC202 - H3K27me3 immunoprecipitation

description:
BT245 SHC202 H3K27me3
230516 BT245 H3K27me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - H3K4me3 immunoprecipitation

description:
GBM1 P612 H3K4me3
230516 GBM1 H3K4me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 -H3K4me3 immunoprecipitation

description:
GBM1 P446 H3K4me3
230516 GBM1 H3K4me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - H3K27me3 immunoprecipitation

description:
GBM1 P612 H3K27me3
230516 GBM1 H3K27me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with control shRNA SHC202 - H3K4me3 immunoprecipitation

description:
GBM1 SHC202 H3K4me3
230516 GBM1 H3K4me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: Healthy donor_018

description: Bone marrow biopsy


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - H3K4me3 immunoprecipitation

description:
BT245 P446 H3K4me3
230516 BT245 H3K4me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - H3K4me3 immunoprecipitation

description:
BT245 P130 H3K4me3
230516 BT245 H3K4me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: BT245 cells transduced with control shRNA SHC202 - H3K4me3 immunoprecipitation

description:
BT245 SHC202 H3K4me3
230516 BT245 H3K4me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - H3K27me3 immunoprecipitation

description:
BT245 P446 H3K27me3
230516 BT245 H3K27me3 PRMT5_merged vs SHC202, all unique_peaks with values.csv


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 - IgG immunoprecipitation

description: GBM1 P446 IgG

value: IgG


title: Healthy donor_015

description: Bone marrow biopsy


title: Healthy donor_014

description: Bone marrow biopsy


title: GBM1 cells transduced with control shRNA SHC202 - IgG immunoprecipitation

description: GBM1 SHC202 IgG


title: Healthy donor_019

description: Bone marrow biopsy


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - IgG immunoprecipitation

description: BT245 P446 IgG


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - IgG immunoprecipitation

description: BT245 P130 IgG


title: PoolA_REP2_DMSO_END

first: Mariano

last: Oppikofer

address: 450 East 29th Street

data_processing:
sequence fastQC, align to library sequences, sgRNA-level and gene-level counts matrix were generated; the count files were feed to MAGeCK (MLE or RRA) to calculate gene-level selection scores.
Assembly: GRCh38
Supplementary files format and content: sgRNA count matrix, gene matrix, MAGeCK-RRA or MLE output (indicating gene selection)
Library strategy: CRISPR-screening

extract_protocol:
gDNA from cell pellets was isolated using QIAGEN Gentra Puregene kit.
Genome-integrated sgRNA sequences were amplified by PCR using KOD Hot Start Polymerases. i5 and i7 multiplexing barcodes (Ilumina) were added in a second round of PCR and final gel-purified products were sequenced.

tag: time point

value: Day 11


title: PoolA_REP2_FDU_END


title: PoolA_REP1_FDU_END


title: BT245 cells transduced with control shRNA SHC202 - IgG immunoprecipitation

description: BT245 SHC202 IgG


title: PoolA_REP1_DMSO_END


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - IgG immunoprecipitation

description: GBM1 P612 IgG


title: Healthy donor_010

description: Bone marrow biopsy

value: Healthy donor


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - input sample

description: GBM1 P612 Input


title: Healthy donor_003

description: Bone marrow biopsy


title: Healthy donor_059

description: Bone marrow biopsy


title: Healthy donor_011

description: Bone marrow biopsy


title: Healthy donor_008

description: Bone marrow biopsy


title: Healthy donor_016

description: Bone marrow biopsy


title: Healthy donor_012

description: Bone marrow biopsy


title: PoolA_REP2_T0

value: Day 0


title: Healthy donor_017

description: Bone marrow biopsy


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 - input sample

description: GBM1 P446 Input


title: PoolA_REP1_T0


title: Healthy donor_007

description: Bone marrow biopsy


title: Healthy donor_001

description: Bone marrow biopsy


title: Healthy donor_004

description: Bone marrow biopsy


title: Healthy donor_005

description: Bone marrow biopsy


title: Healthy donor_006

description: Bone marrow biopsy


title: GBM1 cells transduced with control shRNA SHC202 - input sample

description: GBM1 SHC202 Input


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - input sample

description: BT245 P446 Input


title: Healthy donor_013

description: Bone marrow biopsy


title: rZ10b_IGO_07618_V_36_S27

description:
T11  passage 10b
T11 passage 10b bulkRNAseq

value: human PDX


title: Healthy donor_002

description: Bone marrow biopsy


title: BT245 cells transduced with control shRNA SHC202 - input sample

description: BT245 SHC202 Input


title: BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - input sample

description: BT245 P130 Input


title: rZ8a_IGO_07618_V_32_S24

description:
T11  passage 8a
T11 passage 8a bulkRNAseq

value: primary cells


title: rZ8b_IGO_07618_V_33_S25

description:
T11  passage 8b
T11 passage 8b bulkRNAseq


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612

description: GBM1 PRMT5_612

data_processing:
Alignment to GrCh38 (gSNAP)
FPKD expression derived (Cufflinks)
Differential expression (ANOVA in R)
Assembly: GrCh38
Supplementary files format and content: Tagb-delimited text
Supplementary files format and content: Data file columns:  Ensembl ID, gene_short_name, locus, FPKM, FPKM_conf_lo, FPKM_conf_hi, FPKM_status

extract_protocol:
RNA was extracted from 1e6 cells using the RNEasy Mini Kit (Qiagen)
Sequencing libraries of polyA RNA were prepared using the TruSeq Library Preparation Kit v2 (Agilent)


title: rZ10a_IGO_07618_V_35_S26

description:
T11  passage 10a
T11 passage 10a bulkRNAseq


title: rZ4a_IGO_07618_V_24_S20

description:
T11  passage 4a
T11 passage 4a bulkRNAseq


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446

description: GBM1 PRMT5_446


title: rZ0b_IGO_07618_V_23_S19

description:
T11  passage 0b
T11 passage 0b bulkRNAseq


title: DIPG13* cells transduced with PRMT targeting shRNA TRCN0000379612

description: DIPG13* PRMT5_612

source_name: pons

value: pons

value: SU-DIPG-XIII*


title: DIPG13* cells transduced with PRMT targeting shRNA TRCN0000303446

description: DIPG13* PRMT5_446


title: B8a_IGO_07618_K_11_S13

description:
T10  passage 8a
T10 passage 8a bulkRNAseq


title: B8b_IGO_07618_K_12_S4

description:
T10  passage 8b
T10 passage 8b bulkRNAseq


title: B2a_IGO_07618_K_17_S6

description:
T10  passage 2a
T10 passage 2a bulkRNAseq


title: DIPG13* cells transduced with PRMT targeting shRNA TRCN0000381130

description: DIPG13* PRMT5_130


title: V8b_IGO_07618_K_10_S3

description:
T9  passage 8b
T9 passage 8b bulkRNAseq


title: DIPG13* cells transduced with control shRNA SHC202

description: DIPG13* SHC_202


title: DIPG7 cells transduced with PRMT targeting shRNA TRCN0000379612

description: DIPG7 PRMT5_612


title: B1b_IGO_07618_K_9_S12

description:
T10  passage 1b
T10 passage 1b bulkRNAseq


title: V8a_IGO_07618_K_8_S11

description:
T9  passage 8a
T9 passage 8a bulkRNAseq


title: DIPG7 cells transduced with PRMT targeting shRNA TRCN0000303446

description: DIPG7 PRMT5_446


title: V4b_IGO_07618_K_7_S19

description:
T8  passage 4b
T9 passage 4b bulkRNAseq


title: DIPG7 cells transduced with PRMT targeting shRNA TRCN0000381130

description: DIPG7 PRMT5_130


title: V3a_IGO_07618_K_5_S9

description:
T8  passage 3a
T9 passage 3a bulkRNAseq


title: V4a_IGO_07618_K_6_S10

description:
T8  passage 4a
T9 passage 4a bulkRNAseq


title: DIPG7 cells transduced with control shRNA SHC202

description: DIPG7 SHC_202


title: O9a_IGO_07618_K_16_S15

description:
T8  passage 9a
T8 passage 9a bulkRNAseq


title: GBM1 cells transduced with PRMT targeting shRNA TRCN0000381130

description: GBM1 PRMT5_130


title: GBM1 cells transduced with control shRNA SHC202

description: GBM1 SHC_202


title: DIPG4 cells transduced with PRMT targeting shRNA TRCN0000379612

description: DIPG4 PRMT5_612

value: SU-DIPG-IV


title: DIPG4 cells transduced with PRMT targeting shRNA TRCN0000381130

description: DIPG4 PRMT5_130


title: DIPG4 cells transduced with PRMT targeting shRNA TRCN0000303446

description: DIPG4 PRMT5_446


title: DIPG4 cells transduced with control shRNA SHC202

description: DIPG4 SHC_202


title: O3b_IGO_07618_K_19_S16

description:
T8  passage 3b
T8 passage 3b bulkRNAseq


title: O8c_IGO_07618_K_15_S14

description:
T8  passage 8c
T8 passage 8c bulkRNAseq