title: Male Kidney, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p09_10109_r31_k

value: Kidney


title: Male Kidney, 16.7 mg/kg/day 73FTOH, Animal r29

status: Public on Jun 26 2025

type: SRA

city: RTP

first: Logan

middle: J

last: Everett

state: North Carolina

address: 109 T.W. Alexander Dr

department: Office of Research and Development

country: USA

institute: U.S. Environmental Protection Agency

description: Library name: p09_10109_r29_k

library_source: transcriptomic

data_processing:
Raw sequencing reads (FASTQ files) were aligned to known probe sequences listed in the TempO-Seq probe manifest using HISAT2 to compute a matrix of read counts for each probe in each sample.
Assembly: TempO-seq Rat S1500+ v1.2
Supplementary files format and content: Count table CSV files contain a row for each known probe and a column for each sample. Each cell contains the number of reads from a single cell uniquely aligned to a single probe sequence
Supplementary files format and content: Probe manifest CSV file contains a row for each known probe with the probe name, sequence, and target gene

molecule: total RNA

organism: Rattus norvegicus

source_name: Kidney

growth_protocol: Male and female Sprague Dawley (Crl:CD(SD), Charles River Laboratory) rats are purchased at 6 – 8 weeks of age. Upon receipt, the animals are placed on a standard, purified laboratory diet and reverse osmosis treated drinking water ad libitum. The specific brand and type of food and source of the water should be noted in Appendix II (Detailed Animal Study Report) of the individual assessment. After a 7- to 14-day quarantine and acclimation period, the animals are weighed and randomly assigned by weight to chemical exposure and control groups. Only clinically healthy animals are used in the study. The target age for initiating exposure is 8 - 10 weeks.

extract_protocol:
Treated and control animals are necropsied approximately 24 hours after the last exposure. Carbon dioxide asphyxiation is used as the method of euthanasia, with death confirmed by a secondary method such as exsanguination or cervical dislocation. The following tissues were dissected from each animal: kidney, liver, adrenal gland, brain, heart, lung, ovary (females), spleen, testis (males), thyroid, thymus, and uterus (females). Tissue samples were collected within ten minutes of termination. The left liver lobe, right kidney, left lung, both testis, uterus, heart, spleen, thymus and whole brain were sectioned into 5mm^3 pieces. Samples from these larger tissues were then individually divided into at least 3 cryovials. At least two of the samples from each tissue in each animal were preserved in RNAlater™ (Thermo Fisher Scientific) at 4°C overnight and then frozen at approximately -20°C for up to 3 weeks before transferring to approximately -80°C. At least one sample from each larger tissue is frozen immediately in liquid nitrogen and stored at approximately -80°C.   The smaller bilateral tissues: adrenal glands, thyroid gland, and ovaries (female) are placed into two cryovials and preserved in RNALater with the left side of the tissue or gland going into the first cryovial and the right side going into the second cryovial. The first tube of RNALater preserved tissue is submitted for sequencing. For each tissue undergoing transcriptomic analysis, total RNA is extracted from one of the aliquots stored in RNAlater™.
The isolated total RNA is used to perform targeted RNA sequencing (RNA-seq) using the BioSpyder TempO-Seq rat S1500+ assay (v1.2) according to manufacturer’s instructions. No specific RNA purity or integrity criteria are applied to the RNA samples as the TempO-Seq assay has been designed to provide high quality gene expression measurements on whole cell lysates, purified RNA, and formalin-fixed paraffin embedded tissue.

treatment_protocol: For oral gavage studies, at least four male and four female rats per dose group receive the vehicle alone or test article in vehicle via gavage (5 or 10 ml/kg) for five days. Animals are weighed daily prior to administration and are observed twice daily, once during administration and once in the late afternoon, at least six hours apart, for assessment of moribundity and mortality. Formal clinical observations are performed on the first day post-dosing and prior to necropsy. Moribund animals or animals exhibiting overt clinical toxicity are removed from the study. The temperature in the experimental animal room is maintained at a target of 22°C (± 3°C) with a relative humidity that is ideally between 50-60% but is at least 30% and preferably not to exceed 70% other than during room cleaning. Lighting is artificial with a sequence of 12 hours light, 12 hours dark. Animals are housed individually or caged in small groups of no more than three animals of the same sex in accordance with local institutional animal care and use requirements.

tag: Sex

value: Male

tag: tissue

tag: strain

value: Sprague Dawley

tag: age

value: 8-10 weeks

tag: treatment

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

tag: sample qc_issue

value: No Issue


title: Male Kidney, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p09_10109_r26_k

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Kidney, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p09_10109_r30_k


title: Male Kidney, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p09_10109_r25_k


title: Male Kidney, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p09_10109_r27_k


title: Male Kidney, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p09_10109_r28_k


title: Male Kidney, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p09_10109_r22_k

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Kidney, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p09_10109_r23_k


title: Male Kidney, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p09_10109_r17_k

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Kidney, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p09_10109_r19_k

value: Male

value: Kidney

value: Sprague Dawley


title: Male Kidney, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p09_10109_r18_k

value: 8-10 weeks


title: Male Kidney, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p09_10109_r16_k


title: Male Kidney, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p09_10109_r20_k


title: Male Kidney, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p09_10109_r09_k

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Kidney, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p09_10109_r14_k

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

value: No Issue


title: Male Kidney, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p09_10109_r10_k


title: Male Kidney, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p09_10109_r15_k


title: Male Kidney, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p09_10109_r12_k


title: Male Kidney, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p09_10109_r11_k


title: Male Kidney, Vehicle Control, Animal r07

description: Library name: p09_10109_r07_k

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Kidney, Vehicle Control, Animal r06

description: Library name: p09_10109_r06_k


title: Male Kidney, Vehicle Control, Animal r08

description: Library name: p09_10109_r08_k


title: Male Kidney, Vehicle Control, Animal r03

description: Library name: p09_10109_r03_k


title: Male Kidney, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p09_10109_r24_k

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Kidney, Vehicle Control, Animal r04

description: Library name: p09_10109_r04_k


title: Male Kidney, Vehicle Control, Animal r01

description: Library name: p09_10109_r01_k


title: Male Kidney, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p09_10109_r21_k

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Kidney, Vehicle Control, Animal r05

description: Library name: p09_10109_r05_k

value: Male

value: Kidney

value: Sprague Dawley


title: Male Kidney, Vehicle Control, Animal r02

description: Library name: p09_10109_r02_k

value: 8-10 weeks


title: Female Heart, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p06_10109_r94_h

source_name: Heart

value: Female

value: Heart

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Heart, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p06_10109_r91_h

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

value: No Issue


title: Female Heart, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p06_10109_r96_h


title: Female Heart, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p06_10109_r92_h


title: Female Heart, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p06_10109_r95_h


title: Female Heart, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p06_10109_r90_h


title: Male Kidney, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p09_10109_r13_k

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Heart, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p06_10109_r93_h


title: Female Heart, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p06_10109_r89_h


title: Female Heart, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p06_10109_r88_h


title: Female Heart, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p06_10109_r87_h


title: Female Heart, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p06_10109_r84_h

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Heart, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p06_10109_r85_h

value: Female

value: Sprague Dawley

value: 8-10 weeks


title: Female Heart, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p06_10109_r86_h

value: Heart


title: Female Heart, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p06_10109_r82_h


title: Female Heart, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p06_10109_r83_h


title: Female Heart, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p06_10109_r79_h

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Heart, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p06_10109_r81_h


title: Female Heart, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p06_10109_r80_h


title: Female Heart, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p06_10109_r78_h


title: Female Heart, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p06_10109_r76_h

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Heart, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p06_10109_r77_h

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

value: No Issue


title: Female Heart, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p06_10109_r74_h


title: Female Heart, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p06_10109_r75_h


title: Female Heart, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p06_10109_r73_h


title: Female Heart, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p06_10109_r72_h


title: Female Heart, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p06_10109_r70_h

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Heart, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p06_10109_r71_h


title: Female Heart, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p06_10109_r67_h


title: Female Heart, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p06_10109_r69_h


title: Female Heart, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p06_10109_r66_h

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Heart, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p06_10109_r63_h

value: Female

value: Sprague Dawley

value: 8-10 weeks


title: Female Heart, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p06_10109_r60_h

value: Heart

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Heart, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p06_10109_r59_h


title: Female Heart, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p06_10109_r58_h


title: Female Heart, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p06_10109_r61_h


title: Female Heart, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p06_10109_r64_h


title: Female Heart, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p06_10109_r65_h


title: Female Heart, Vehicle Control, Animal r52

description: Library name: p06_10109_r52_h

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Heart, Vehicle Control, Animal r49

description: Library name: p06_10109_r49_h

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

value: No Issue


title: Female Heart, Vehicle Control, Animal r51

description: Library name: p06_10109_r51_h


title: Male Heart, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p05_10109_r46_h

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Heart, Vehicle Control, Animal r54

description: Library name: p06_10109_r54_h

value: Female


title: Female Heart, Vehicle Control, Animal r55

description: Library name: p06_10109_r55_h

value: Sprague Dawley


title: Female Heart, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p06_10109_r68_h

value: 8-10 weeks

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Heart, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p05_10109_r43_h

value: Heart

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Heart, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p05_10109_r44_h

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Heart, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p05_10109_r42_h

value: route of_exposure:Oral gavage


title: Male Heart, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p05_10109_r41_h

value: No Issue


title: Female Heart, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p06_10109_r62_h

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Heart, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p05_10109_r40_h

value: Male


title: Male Heart, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p05_10109_r38_h

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Heart, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p05_10109_r36_h

value: Sprague Dawley

value: 8-10 weeks


title: Female Heart, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p06_10109_r57_h

value: Female

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Heart, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p05_10109_r39_h

value: Heart

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Heart, Vehicle Control, Animal r53

description: Library name: p06_10109_r53_h

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

value: No Issue


title: Male Heart, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p05_10109_r34_h

value: Male

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Heart, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p05_10109_r35_h

value: Sprague Dawley

value: 8-10 weeks


title: Male Heart, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p05_10109_r48_h

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Heart, Vehicle Control, Animal r56

description: Library name: p06_10109_r56_h

value: Female

value: Heart


title: Male Heart, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p05_10109_r32_h

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Heart, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p05_10109_r31_h

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: Outlier sample removed


title: Female Heart, Vehicle Control, Animal r50

description: Library name: p06_10109_r50_h

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: route of_exposure:Oral gavage

value: No Issue


title: Male Heart, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p05_10109_r33_h

value: Male

value: Sprague Dawley


title: Male Heart, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p05_10109_r47_h

value: 8-10 weeks

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Male Heart, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p05_10109_r26_h

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Heart, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p05_10109_r29_h

value: Heart

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Male Heart, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p05_10109_r27_h


title: Male Heart, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p05_10109_r28_h


title: Male Heart, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p05_10109_r25_h


title: Male Heart, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p05_10109_r24_h


title: Male Heart, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p05_10109_r23_h

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Heart, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p05_10109_r22_h

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Heart, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p05_10109_r19_h


title: Male Heart, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p05_10109_r20_h


title: Male Heart, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p05_10109_r21_h


title: Male Heart, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p05_10109_r17_h

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Heart, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p05_10109_r16_h

value: route of_exposure:Oral gavage

value: No Issue


title: Male Heart, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p05_10109_r15_h

value: Male

value: Sprague Dawley


title: Male Heart, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p05_10109_r18_h

value: 8-10 weeks


title: Male Heart, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p05_10109_r14_h


title: Male Heart, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p05_10109_r13_h

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Heart, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p05_10109_r12_h

value: Heart


title: Male Heart, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p05_10109_r11_h


title: Male Heart, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p05_10109_r30_h

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Heart, Vehicle Control, Animal r05

description: Library name: p05_10109_r05_h

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Heart, Vehicle Control, Animal r08

description: Library name: p05_10109_r08_h

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Heart, Vehicle Control, Animal r07

description: Library name: p05_10109_r07_h


title: Male Heart, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p05_10109_r09_h


title: Male Heart, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p05_10109_r10_h


title: Male Heart, Vehicle Control, Animal r06

description: Library name: p05_10109_r06_h


title: Male Heart, Vehicle Control, Animal r03

description: Library name: p05_10109_r03_h


title: Male Heart, Vehicle Control, Animal r04

description: Library name: p05_10109_r04_h


title: Female Brain, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p04_10109_r96_b

source_name: Brain

value: Female

value: Brain

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Heart, Vehicle Control, Animal r01

description: Library name: p05_10109_r01_h

value: Male

value: Sprague Dawley

value: 8-10 weeks

value: route of_exposure:Oral gavage

value: No Issue


title: Female Brain, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p04_10109_r95_b


title: Female Brain, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p04_10109_r94_b


title: Male Heart, Vehicle Control, Animal r02

description: Library name: p05_10109_r02_h

value: Heart


title: Female Brain, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p04_10109_r93_b


title: Female Brain, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p04_10109_r92_b


title: Female Brain, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p04_10109_r91_b

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Brain, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p04_10109_r89_b


title: Female Brain, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p04_10109_r90_b

value: < 50% reads aligned


title: Female Brain, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p04_10109_r88_b


title: Female Brain, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p04_10109_r87_b


title: Female Brain, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p04_10109_r86_b

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Brain, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p04_10109_r85_b

value: Female

value: Brain

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Brain, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p04_10109_r80_b

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Brain, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p04_10109_r81_b

value: Sprague Dawley

value: 8-10 weeks


title: Female Brain, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p04_10109_r78_b

value: route of_exposure:Oral gavage

value: No Issue


title: Female Brain, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p04_10109_r74_b

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Brain, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p04_10109_r77_b


title: Female Brain, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p04_10109_r76_b


title: Female Brain, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p04_10109_r75_b


title: Female Brain, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p04_10109_r71_b

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Brain, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p04_10109_r73_b


title: Female Brain, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p04_10109_r72_b


title: Female Brain, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p04_10109_r70_b


title: Female Brain, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p04_10109_r69_b


title: Female Brain, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p04_10109_r65_b

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Brain, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p04_10109_r63_b

value: Female

value: Brain

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Brain, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p04_10109_r67_b


title: Female Brain, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p04_10109_r62_b


title: Female Brain, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p04_10109_r84_b

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Brain, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p04_10109_r61_b

value: Sprague Dawley

value: 8-10 weeks

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: route of_exposure:Oral gavage


title: Female Brain, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p04_10109_r59_b

value: No Issue


title: Female Brain, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p04_10109_r60_b


title: Female Brain, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p04_10109_r58_b


title: Female Brain, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p04_10109_r82_b


title: Female Brain, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p04_10109_r57_b


title: Female Brain, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p04_10109_r83_b


title: Female Brain, Vehicle Control, Animal r56

description: Library name: p04_10109_r56_b

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Brain, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p04_10109_r79_b

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Brain, Vehicle Control, Animal r54

description: Library name: p04_10109_r54_b

value: Female

value: Brain

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Brain, Vehicle Control, Animal r55

description: Library name: p04_10109_r55_b


title: Female Brain, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p04_10109_r68_b

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Brain, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p04_10109_r66_b

value: Sprague Dawley

value: 8-10 weeks

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Brain, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p04_10109_r64_b

value: route of_exposure:Oral gavage

value: No Issue


title: Female Brain, Vehicle Control, Animal r49

description: Library name: p04_10109_r49_b

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Brain, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p03_10109_r48_b

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Brain, Vehicle Control, Animal r50

description: Library name: p04_10109_r50_b

value: Female

value: Brain

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Brain, Vehicle Control, Animal r51

description: Library name: p04_10109_r51_b

value: Sprague Dawley


title: Male Brain, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p03_10109_r47_b

value: 8-10 weeks


title: Female Brain, Vehicle Control, Animal r52

description: Library name: p04_10109_r52_b


title: Female Brain, Vehicle Control, Animal r53

description: Library name: p04_10109_r53_b


title: Male Brain, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p03_10109_r46_b


title: Male Brain, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p03_10109_r44_b

value: < 10% of target read depth


title: Male Brain, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p03_10109_r40_b

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Brain, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p03_10109_r42_b

value: route of_exposure:Oral gavage

value: No Issue


title: Male Brain, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p03_10109_r43_b


title: Male Brain, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p03_10109_r39_b


title: Male Brain, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p03_10109_r37_b

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Brain, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p03_10109_r38_b

value: Male


title: Male Brain, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p03_10109_r35_b


title: Male Brain, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p03_10109_r36_b


title: Male Brain, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p03_10109_r31_b

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Brain, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p03_10109_r29_b

value: Brain


title: Male Brain, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p03_10109_r32_b

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Brain, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p03_10109_r33_b

value: Sprague Dawley


title: Male Brain, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p03_10109_r34_b

value: 8-10 weeks


title: Male Brain, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p03_10109_r30_b


title: Male Brain, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p03_10109_r28_b

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Brain, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p03_10109_r27_b


title: Male Brain, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p03_10109_r23_b

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Brain, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p03_10109_r18_b

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2

value: route of_exposure:Oral gavage

value: No Issue


title: Male Brain, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p03_10109_r17_b

value: Male


title: Male Brain, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p03_10109_r26_b


title: Male Brain, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p03_10109_r24_b


title: Male Brain, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p03_10109_r20_b


title: Male Brain, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p03_10109_r25_b


title: Male Brain, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p03_10109_r19_b


title: Male Brain, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p03_10109_r16_b


title: Male Brain, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p03_10109_r15_b


title: Male Brain, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p03_10109_r41_b

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Brain, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p03_10109_r12_b

value: Brain

value: Sprague Dawley

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Brain, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p03_10109_r22_b

value: 8-10 weeks

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day


title: Male Brain, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p03_10109_r21_b

value: dose group:3


title: Male Brain, Vehicle Control, Animal r08

description: Library name: p03_10109_r08_b

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Brain, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p03_10109_r09_b

value: Male

value: route of_exposure:Oral gavage

value: No Issue


title: Male Brain, Vehicle Control, Animal r07

description: Library name: p03_10109_r07_b


title: Male Brain, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p03_10109_r13_b


title: Male Brain, Vehicle Control, Animal r06

description: Library name: p03_10109_r06_b


title: Male Brain, Vehicle Control, Animal r03

description: Library name: p03_10109_r03_b


title: Male Brain, Vehicle Control, Animal r05

description: Library name: p03_10109_r05_b


title: Male Brain, Vehicle Control, Animal r04

description: Library name: p03_10109_r04_b


title: Female Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p02_10109_r96_a

source_name: Adrenal Gland

value: Female

value: Adrenal Gland

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Brain, Vehicle Control, Animal r01

description: Library name: p03_10109_r01_b

value: Brain

value: Sprague Dawley


title: Male Brain, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p03_10109_r10_b

value: 8-10 weeks

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p02_10109_r95_a


title: Female Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p02_10109_r89_a

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p02_10109_r91_a

value: route of_exposure:Oral gavage


title: Female Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p02_10109_r90_a

value: No Issue


title: Female Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p02_10109_r92_a

value: Female


title: Female Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p02_10109_r94_a

value: Adrenal Gland


title: Female Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p02_10109_r93_a

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Female Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p02_10109_r88_a


title: Male Brain, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p03_10109_r11_b

value: Male


title: Male Brain, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p03_10109_r14_b

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p02_10109_r87_a

value: Sprague Dawley

value: 8-10 weeks


title: Female Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p02_10109_r85_a

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p02_10109_r86_a

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p02_10109_r84_a


title: Female Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p02_10109_r82_a


title: Male Brain, Vehicle Control, Animal r02

description: Library name: p03_10109_r02_b

value: Brain

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p02_10109_r79_a

value: Female

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5

value: route of_exposure:Oral gavage

value: No Issue


title: Female Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p02_10109_r77_a

value: Adrenal Gland


title: Female Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p02_10109_r76_a

value: Sprague Dawley

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p02_10109_r75_a

value: 8-10 weeks


title: Female Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p02_10109_r78_a

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p02_10109_r74_a


title: Female Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p02_10109_r80_a


title: Female Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p02_10109_r71_a

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p02_10109_r72_a


title: Female Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p02_10109_r70_a


title: Female Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p02_10109_r73_a


title: Female Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p02_10109_r67_a


title: Female Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p02_10109_r66_a

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p02_10109_r65_a

value: Female


title: Female Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p02_10109_r68_a


title: Female Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p02_10109_r63_a


title: Female Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p02_10109_r62_a


title: Female Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p02_10109_r83_a

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p02_10109_r81_a

value: Adrenal Gland

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5

value: route of_exposure:Oral gavage

value: No Issue


title: Female Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p02_10109_r60_a

value: Sprague Dawley

value: 8-10 weeks

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p02_10109_r61_a


title: Female Adrenal Gland, Vehicle Control, Animal r56

description: Library name: p02_10109_r56_a

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p02_10109_r58_a

value: Female


title: Female Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p02_10109_r57_a


title: Female Adrenal Gland, Vehicle Control, Animal r54

description: Library name: p02_10109_r54_a


title: Female Adrenal Gland, Vehicle Control, Animal r51

description: Library name: p02_10109_r51_a


title: Female Adrenal Gland, Vehicle Control, Animal r52

description: Library name: p02_10109_r52_a


title: Female Adrenal Gland, Vehicle Control, Animal r50

description: Library name: p02_10109_r50_a


title: Female Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p02_10109_r69_a

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Adrenal Gland, Vehicle Control, Animal r53

description: Library name: p02_10109_r53_a

value: Adrenal Gland


title: Male Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p01_10109_r47_a

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Adrenal Gland, Vehicle Control, Animal r49

description: Library name: p02_10109_r49_a

value: Sprague Dawley

value: 8-10 weeks

value: route of_exposure:Oral gavage

value: No Issue


title: Male Heart, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p05_10109_r37_h

value: Heart

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p01_10109_r43_a

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p01_10109_r42_a

value: Adrenal Gland


title: Female Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p02_10109_r64_a

value: Female

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p01_10109_r46_a

value: Male

value: Sprague Dawley

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p01_10109_r41_a

value: 8-10 weeks

value: route of_exposure:Oral gavage

value: No Issue


title: Male Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p01_10109_r38_a

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p01_10109_r40_a

value: Adrenal Gland

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p01_10109_r48_a


title: Male Adrenal Gland, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p01_10109_r39_a


title: Female Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p02_10109_r59_a

value: Female

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p01_10109_r34_a

value: Male

value: Sprague Dawley


title: Female Adrenal Gland, Vehicle Control, Animal r55

description: Library name: p02_10109_r55_a

value: 8-10 weeks

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p01_10109_r33_a

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5

value: route of_exposure:Oral gavage

value: No Issue


title: Male Adrenal Gland, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p01_10109_r44_a

value: Adrenal Gland

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p01_10109_r36_a

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p01_10109_r35_a

value: Male

value: Sprague Dawley

value: 8-10 weeks


title: Male Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p01_10109_r32_a


title: Male Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p01_10109_r31_a


title: Male Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p01_10109_r28_a

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p01_10109_r27_a


title: Male Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p01_10109_r30_a

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p01_10109_r26_a

value: Adrenal Gland

value: route of_exposure:Oral gavage

value: No Issue


title: Male Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p01_10109_r25_a


title: Male Adrenal Gland, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p01_10109_r24_a


title: Male Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p01_10109_r23_a

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p01_10109_r22_a

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p01_10109_r19_a


title: Male Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p01_10109_r18_a

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p01_10109_r17_a

value: Male

value: Sprague Dawley

value: 8-10 weeks


title: Male Adrenal Gland, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p01_10109_r37_a

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p01_10109_r16_a


title: Male Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p01_10109_r15_a


title: Male Adrenal Gland, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p01_10109_r14_a


title: Male Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p01_10109_r10_a

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p01_10109_r11_a

value: Adrenal Gland

value: route of_exposure:Oral gavage

value: No Issue


title: Male Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p01_10109_r13_a


title: Male Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p01_10109_r09_a


title: Male Adrenal Gland, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p01_10109_r12_a


title: Male Adrenal Gland, Vehicle Control, Animal r07

description: Library name: p01_10109_r07_a

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Adrenal Gland, Vehicle Control, Animal r08

description: Library name: p01_10109_r08_a

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Adrenal Gland, Vehicle Control, Animal r05

description: Library name: p01_10109_r05_a


title: Male Adrenal Gland, Vehicle Control, Animal r04

description: Library name: p01_10109_r04_a


title: Male Adrenal Gland, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p01_10109_r29_a

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Adrenal Gland, Vehicle Control, Animal r06

description: Library name: p01_10109_r06_a

value: Male

value: Sprague Dawley

value: 8-10 weeks


title: Male Adrenal Gland, Vehicle Control, Animal r03

description: Library name: p01_10109_r03_a


title: Male Adrenal Gland, Vehicle Control, Animal r02

description: Library name: p01_10109_r02_a


title: p23_10104_r95_u

description: Library name: p23_10104_r95_u

source_name: Female Uterus, 100 mg/kg/day FTCA, Animal r95

growth_protocol: Male and female Sprague Dawley (Crl:CD IGS, Charles River Laboratory) rats are purchased at 6 – 8 weeks of age. Upon receipt, the animals are placed on a standard, purified laboratory diet and reverse osmosis treated drinking water ad libitum. The specific brand and type of food and source of the water should be noted in Appendix II (Detailed Animal Study Report) of the individual assessment. After a 7- to 14-day quarantine and acclimation period, the animals are weighed and randomly assigned by weight to chemical exposure and control groups. Only clinically healthy animals are used in the study. The target age for initiating exposure is 8 - 10 weeks.

value: Female

value: Uterus

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p23_10104_r94_u

description: Library name: p23_10104_r94_u

source_name: Female Uterus, 100 mg/kg/day FTCA, Animal r94

value: route of_exposure:Oral gavage

value: No Issue


title: Male Adrenal Gland, Vehicle Control, Animal r01

description: Library name: p01_10109_r01_a

value: Adrenal Gland

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day


title: Male Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p01_10109_r21_a

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: p23_10104_r93_u

description: Library name: p23_10104_r93_u

source_name: Female Uterus, 100 mg/kg/day FTCA, Animal r93

value: Sprague Dawley


title: p23_10104_r96_u

description: Library name: p23_10104_r96_u

source_name: Female Uterus, 100 mg/kg/day FTCA, Animal r96

value: 8-10 weeks


title: p23_10104_r91_u

description: Library name: p23_10104_r91_u

source_name: Female Uterus, 30 mg/kg/day FTCA, Animal r91

value: Female

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: p23_10104_r92_u

description: Library name: p23_10104_r92_u

source_name: Female Uterus, 100 mg/kg/day FTCA, Animal r92

value: Uterus

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: Male Adrenal Gland, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p01_10109_r20_a

value: Male

value: Adrenal Gland

value: route of_exposure:Oral gavage

value: No Issue


title: p23_10104_r90_u

description: Library name: p23_10104_r90_u

source_name: Female Uterus, 30 mg/kg/day FTCA, Animal r90

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p23_10104_r88_u

description: Library name: p23_10104_r88_u

source_name: Female Uterus, 30 mg/kg/day FTCA, Animal r88


title: p23_10104_r86_u

description: Library name: p23_10104_r86_u

source_name: Female Uterus, 10 mg/kg/day FTCA, Animal r86

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p23_10104_r87_u

description: Library name: p23_10104_r87_u

source_name: Female Uterus, 30 mg/kg/day FTCA, Animal r87

value: Sprague Dawley

value: 8-10 weeks


title: p23_10104_r82_u

description: Library name: p23_10104_r82_u

source_name: Female Uterus, 10 mg/kg/day FTCA, Animal r82

value: Female


title: p23_10104_r81_u

description: Library name: p23_10104_r81_u

source_name: Female Uterus, 3 mg/kg/day FTCA, Animal r81

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p23_10104_r84_u

description: Library name: p23_10104_r84_u

source_name: Female Uterus, 10 mg/kg/day FTCA, Animal r84

value: Uterus


title: p23_10104_r79_u

description: Library name: p23_10104_r79_u

source_name: Female Uterus, 3 mg/kg/day FTCA, Animal r79


title: p23_10104_r80_u

description: Library name: p23_10104_r80_u

source_name: Female Uterus, 3 mg/kg/day FTCA, Animal r80


title: p23_10104_r78_u

description: Library name: p23_10104_r78_u

source_name: Female Uterus, 3 mg/kg/day FTCA, Animal r78


title: p23_10104_r77_u

description: Library name: p23_10104_r77_u

source_name: Female Uterus, 3 mg/kg/day FTCA, Animal r77


title: p23_10104_r76_u

description: Library name: p23_10104_r76_u

source_name: Female Uterus, 1 mg/kg/day FTCA, Animal r76

value: 1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: p23_10104_r73_u

description: Library name: p23_10104_r73_u

source_name: Female Uterus, 1 mg/kg/day FTCA, Animal r73


title: p23_10104_r75_u

description: Library name: p23_10104_r75_u

source_name: Female Uterus, 1 mg/kg/day FTCA, Animal r75


title: p23_10104_r71_u

description: Library name: p23_10104_r71_u

source_name: Female Uterus, 0.3 mg/kg/day FTCA, Animal r71

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p23_10104_r70_u

description: Library name: p23_10104_r70_u

source_name: Female Uterus, 0.3 mg/kg/day FTCA, Animal r70

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage

value: No Issue


title: p23_10104_r74_u

description: Library name: p23_10104_r74_u

source_name: Female Uterus, 1 mg/kg/day FTCA, Animal r74


title: p23_10104_r69_u

description: Library name: p23_10104_r69_u

source_name: Female Uterus, 0.3 mg/kg/day FTCA, Animal r69


title: p23_10104_r72_u

description: Library name: p23_10104_r72_u

source_name: Female Uterus, 1 mg/kg/day FTCA, Animal r72


title: p23_10104_r68_u

description: Library name: p23_10104_r68_u

source_name: Female Uterus, 0.3 mg/kg/day FTCA, Animal r68


title: p23_10104_r62_u

description: Library name: p23_10104_r62_u

source_name: Female Uterus, 0.1 mg/kg/day FTCA, Animal r62

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: p23_10104_r65_u

description: Library name: p23_10104_r65_u

source_name: Female Uterus, 0.1 mg/kg/day FTCA, Animal r65

value: Female

value: Sprague Dawley

value: 8-10 weeks


title: p23_10104_r63_u

description: Library name: p23_10104_r63_u

source_name: Female Uterus, 0.1 mg/kg/day FTCA, Animal r63


title: p23_10104_r64_u

description: Library name: p23_10104_r64_u

source_name: Female Uterus, 0.1 mg/kg/day FTCA, Animal r64


title: p23_10104_r66_u

description: Library name: p23_10104_r66_u

source_name: Female Uterus, 0.1 mg/kg/day FTCA, Animal r66


title: p23_10104_r60_u

description: Library name: p23_10104_r60_u

source_name: Female Uterus, 0.01 mg/kg/day FTCA, Animal r60

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p23_10104_r67_u

description: Library name: p23_10104_r67_u

source_name: Female Uterus, 0.3 mg/kg/day FTCA, Animal r67

value: Uterus


title: p23_10104_r61_u

description: Library name: p23_10104_r61_u

source_name: Female Uterus, 0.01 mg/kg/day FTCA, Animal r61


title: p23_10104_r85_u

description: Library name: p23_10104_r85_u

source_name: Female Uterus, 10 mg/kg/day FTCA, Animal r85

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p23_10104_r83_u

description: Library name: p23_10104_r83_u

source_name: Female Uterus, 10 mg/kg/day FTCA, Animal r83


title: p23_10104_r89_u

description: Library name: p23_10104_r89_u

source_name: Female Uterus, 30 mg/kg/day FTCA, Animal r89

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: p23_10104_r58_u

description: Library name: p23_10104_r58_u

source_name: Female Uterus, 0.01 mg/kg/day FTCA, Animal r58

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage

value: No Issue


title: p23_10104_r56_u

description: Library name: p23_10104_r56_u

source_name: Female Uterus, Vehicle Control, Animal r56

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p23_10104_r54_u

description: Library name: p23_10104_r54_u

source_name: Female Uterus, Vehicle Control, Animal r54

value: Female

value: Sprague Dawley

value: 8-10 weeks


title: p23_10104_r52_u

description: Library name: p23_10104_r52_u

source_name: Female Uterus, Vehicle Control, Animal r52


title: p23_10104_r55_u

description: Library name: p23_10104_r55_u

source_name: Female Uterus, Vehicle Control, Animal r55


title: p23_10104_r57_u

description: Library name: p23_10104_r57_u

source_name: Female Uterus, 0.01 mg/kg/day FTCA, Animal r57

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p23_10104_r53_u

description: Library name: p23_10104_r53_u

source_name: Female Uterus, Vehicle Control, Animal r53

value: Uterus


title: p23_10104_r49_u

description: Library name: p23_10104_r49_u

source_name: Female Uterus, Vehicle Control, Animal r49


title: p23_10104_r50_u

description: Library name: p23_10104_r50_u

source_name: Female Uterus, Vehicle Control, Animal r50


title: p23_10104_r51_u

description: Library name: p23_10104_r51_u

source_name: Female Uterus, Vehicle Control, Animal r51


title: p23_10104_r59_u

description: Library name: p23_10104_r59_u

source_name: Female Uterus, 0.01 mg/kg/day FTCA, Animal r59


title: p22_10104_r94_o

description: Library name: p22_10104_r94_o

source_name: Female Ovary, 100 mg/kg/day FTCA, Animal r94

value: Ovary

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: p22_10104_r93_o

description: Library name: p22_10104_r93_o

source_name: Female Ovary, 100 mg/kg/day FTCA, Animal r93

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p22_10104_r95_o

description: Library name: p22_10104_r95_o

source_name: Female Ovary, 100 mg/kg/day FTCA, Animal r95

value: route of_exposure:Oral gavage


title: p22_10104_r91_o

description: Library name: p22_10104_r91_o

source_name: Female Ovary, 30 mg/kg/day FTCA, Animal r91

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7

value: No Issue


title: p22_10104_r92_o

description: Library name: p22_10104_r92_o

source_name: Female Ovary, 100 mg/kg/day FTCA, Animal r92

value: Female


title: p22_10104_r96_o

description: Library name: p22_10104_r96_o

source_name: Female Ovary, 100 mg/kg/day FTCA, Animal r96

value: Sprague Dawley


title: p22_10104_r90_o

description: Library name: p22_10104_r90_o

source_name: Female Ovary, 30 mg/kg/day FTCA, Animal r90

value: 8-10 weeks


title: p22_10104_r89_o

description: Library name: p22_10104_r89_o

source_name: Female Ovary, 30 mg/kg/day FTCA, Animal r89


title: p22_10104_r87_o

description: Library name: p22_10104_r87_o

source_name: Female Ovary, 30 mg/kg/day FTCA, Animal r87


title: p22_10104_r86_o

description: Library name: p22_10104_r86_o

source_name: Female Ovary, 10 mg/kg/day FTCA, Animal r86

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p22_10104_r88_o

description: Library name: p22_10104_r88_o

source_name: Female Ovary, 30 mg/kg/day FTCA, Animal r88


title: p22_10104_r85_o

description: Library name: p22_10104_r85_o

source_name: Female Ovary, 10 mg/kg/day FTCA, Animal r85


title: p22_10104_r79_o

description: Library name: p22_10104_r79_o

source_name: Female Ovary, 3 mg/kg/day FTCA, Animal r79

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p22_10104_r81_o

description: Library name: p22_10104_r81_o

source_name: Female Ovary, 3 mg/kg/day FTCA, Animal r81

value: Ovary


title: p22_10104_r82_o

description: Library name: p22_10104_r82_o

source_name: Female Ovary, 10 mg/kg/day FTCA, Animal r82


title: p22_10104_r80_o

description: Library name: p22_10104_r80_o

source_name: Female Ovary, 3 mg/kg/day FTCA, Animal r80


title: p22_10104_r77_o

description: Library name: p22_10104_r77_o

source_name: Female Ovary, 3 mg/kg/day FTCA, Animal r77


title: p22_10104_r76_o

description: Library name: p22_10104_r76_o

source_name: Female Ovary, 1 mg/kg/day FTCA, Animal r76

value: 1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: p22_10104_r74_o

description: Library name: p22_10104_r74_o

source_name: Female Ovary, 1 mg/kg/day FTCA, Animal r74

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p22_10104_r75_o

description: Library name: p22_10104_r75_o

source_name: Female Ovary, 1 mg/kg/day FTCA, Animal r75


title: p22_10104_r84_o

description: Library name: p22_10104_r84_o

source_name: Female Ovary, 10 mg/kg/day FTCA, Animal r84


title: p22_10104_r72_o

description: Library name: p22_10104_r72_o

source_name: Female Ovary, 1 mg/kg/day FTCA, Animal r72


title: p22_10104_r71_o

description: Library name: p22_10104_r71_o

source_name: Female Ovary, 0.3 mg/kg/day FTCA, Animal r71

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p22_10104_r73_o

description: Library name: p22_10104_r73_o

source_name: Female Ovary, 1 mg/kg/day FTCA, Animal r73

value: Female

value: Sprague Dawley

value: No Issue


title: p22_10104_r78_o

description: Library name: p22_10104_r78_o

source_name: Female Ovary, 3 mg/kg/day FTCA, Animal r78

value: 8-10 weeks


title: p22_10104_r70_o

description: Library name: p22_10104_r70_o

source_name: Female Ovary, 0.3 mg/kg/day FTCA, Animal r70


title: p22_10104_r69_o

description: Library name: p22_10104_r69_o

source_name: Female Ovary, 0.3 mg/kg/day FTCA, Animal r69


title: p22_10104_r66_o

description: Library name: p22_10104_r66_o

source_name: Female Ovary, 0.1 mg/kg/day FTCA, Animal r66

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: p22_10104_r64_o

description: Library name: p22_10104_r64_o

source_name: Female Ovary, 0.1 mg/kg/day FTCA, Animal r64


title: p22_10104_r68_o

description: Library name: p22_10104_r68_o

source_name: Female Ovary, 0.3 mg/kg/day FTCA, Animal r68


title: p22_10104_r61_o

description: Library name: p22_10104_r61_o

source_name: Female Ovary, 0.01 mg/kg/day FTCA, Animal r61

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p22_10104_r62_o

description: Library name: p22_10104_r62_o

source_name: Female Ovary, 0.1 mg/kg/day FTCA, Animal r62

value: Ovary


title: p22_10104_r65_o

description: Library name: p22_10104_r65_o

source_name: Female Ovary, 0.1 mg/kg/day FTCA, Animal r65


title: p22_10104_r83_o

description: Library name: p22_10104_r83_o

source_name: Female Ovary, 10 mg/kg/day FTCA, Animal r83

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p22_10104_r58_o

description: Library name: p22_10104_r58_o

source_name: Female Ovary, 0.01 mg/kg/day FTCA, Animal r58

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p22_10104_r56_o

description: Library name: p22_10104_r56_o

source_name: Female Ovary, Vehicle Control, Animal r56

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p22_10104_r55_o

description: Library name: p22_10104_r55_o

source_name: Female Ovary, Vehicle Control, Animal r55

value: Female

value: Sprague Dawley

value: No Issue


title: p22_10104_r57_o

description: Library name: p22_10104_r57_o

source_name: Female Ovary, 0.01 mg/kg/day FTCA, Animal r57

value: 8-10 weeks


title: p22_10104_r54_o

description: Library name: p22_10104_r54_o

source_name: Female Ovary, Vehicle Control, Animal r54


title: p22_10104_r50_o

description: Library name: p22_10104_r50_o

source_name: Female Ovary, Vehicle Control, Animal r50


title: p22_10104_r53_o

description: Library name: p22_10104_r53_o

source_name: Female Ovary, Vehicle Control, Animal r53


title: p22_10104_r51_o

description: Library name: p22_10104_r51_o

source_name: Female Ovary, Vehicle Control, Animal r51

value: < 50% reads aligned


title: p22_10104_r49_o

description: Library name: p22_10104_r49_o

source_name: Female Ovary, Vehicle Control, Animal r49


title: p22_10104_r52_o

description: Library name: p22_10104_r52_o

source_name: Female Ovary, Vehicle Control, Animal r52


title: p21_10104_r46_t

description: Library name: p21_10104_r46_t

source_name: Male Testis, 100 mg/kg/day FTCA, Animal r46

value: Male

value: Testis

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: p21_10104_r47_t

description: Library name: p21_10104_r47_t

source_name: Male Testis, 100 mg/kg/day FTCA, Animal r47


title: p21_10104_r48_t

description: Library name: p21_10104_r48_t

source_name: Male Testis, 100 mg/kg/day FTCA, Animal r48


title: p21_10104_r44_t

description: Library name: p21_10104_r44_t

source_name: Male Testis, 100 mg/kg/day FTCA, Animal r44


title: p22_10104_r67_o

description: Library name: p22_10104_r67_o

source_name: Female Ovary, 0.3 mg/kg/day FTCA, Animal r67

value: Ovary

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p21_10104_r41_t

description: Library name: p21_10104_r41_t

source_name: Male Testis, 30 mg/kg/day FTCA, Animal r41

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p21_10104_r42_t

description: Library name: p21_10104_r42_t

source_name: Male Testis, 30 mg/kg/day FTCA, Animal r42

value: Sprague Dawley

value: No Issue


title: p22_10104_r63_o

description: Library name: p22_10104_r63_o

source_name: Female Ovary, 0.1 mg/kg/day FTCA, Animal r63

value: Female

value: 8-10 weeks

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: p22_10104_r59_o

description: Library name: p22_10104_r59_o

source_name: Female Ovary, 0.01 mg/kg/day FTCA, Animal r59

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p21_10104_r39_t

description: Library name: p21_10104_r39_t

source_name: Male Testis, 30 mg/kg/day FTCA, Animal r39

value: Male

value: Testis


title: p21_10104_r38_t

description: Library name: p21_10104_r38_t

source_name: Male Testis, 10 mg/kg/day FTCA, Animal r38

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p21_10104_r45_t

description: Library name: p21_10104_r45_t

source_name: Male Testis, 100 mg/kg/day FTCA, Animal r45

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p21_10104_r37_t

description: Library name: p21_10104_r37_t

source_name: Male Testis, 10 mg/kg/day FTCA, Animal r37

value: Sprague Dawley

value: route of_exposure:Oral gavage

value: No Issue


title: p21_10104_r40_t

description: Library name: p21_10104_r40_t

source_name: Male Testis, 30 mg/kg/day FTCA, Animal r40

value: 8-10 weeks

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: p21_10104_r34_t

description: Library name: p21_10104_r34_t

source_name: Male Testis, 10 mg/kg/day FTCA, Animal r34


title: p21_10104_r36_t

description: Library name: p21_10104_r36_t

source_name: Male Testis, 10 mg/kg/day FTCA, Animal r36


title: p21_10104_r31_t

description: Library name: p21_10104_r31_t

source_name: Male Testis, 3 mg/kg/day FTCA, Animal r31

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p21_10104_r32_t

description: Library name: p21_10104_r32_t

source_name: Male Testis, 3 mg/kg/day FTCA, Animal r32

value: Male

value: Testis


title: p22_10104_r60_o

description: Library name: p22_10104_r60_o

source_name: Female Ovary, 0.01 mg/kg/day FTCA, Animal r60

value: Female

value: Ovary

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p21_10104_r29_t

description: Library name: p21_10104_r29_t

source_name: Male Testis, 3 mg/kg/day FTCA, Animal r29

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p21_10104_r30_t

description: Library name: p21_10104_r30_t

source_name: Male Testis, 3 mg/kg/day FTCA, Animal r30

value: route of_exposure:Oral gavage

value: No Issue


title: p21_10104_r28_t

description: Library name: p21_10104_r28_t

source_name: Male Testis, 1 mg/kg/day FTCA, Animal r28

value: 8-10 weeks

value: 1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: p21_10104_r35_t

description: Library name: p21_10104_r35_t

source_name: Male Testis, 10 mg/kg/day FTCA, Animal r35

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p21_10104_r26_t

description: Library name: p21_10104_r26_t

source_name: Male Testis, 1 mg/kg/day FTCA, Animal r26

value: Male

value: Testis


title: p21_10104_r25_t

description: Library name: p21_10104_r25_t

source_name: Male Testis, 1 mg/kg/day FTCA, Animal r25


title: p21_10104_r27_t

description: Library name: p21_10104_r27_t

source_name: Male Testis, 1 mg/kg/day FTCA, Animal r27


title: p21_10104_r33_t

description: Library name: p21_10104_r33_t

source_name: Male Testis, 3 mg/kg/day FTCA, Animal r33

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p21_10104_r23_t

description: Library name: p21_10104_r23_t

source_name: Male Testis, 0.3 mg/kg/day FTCA, Animal r23

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p21_10104_r24_t

description: Library name: p21_10104_r24_t

source_name: Male Testis, 1 mg/kg/day FTCA, Animal r24

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p21_10104_r43_t

description: Library name: p21_10104_r43_t

source_name: Male Testis, 30 mg/kg/day FTCA, Animal r43

value: 8-10 weeks

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7

value: No Issue


title: p21_10104_r21_t

description: Library name: p21_10104_r21_t

source_name: Male Testis, 0.3 mg/kg/day FTCA, Animal r21


title: p21_10104_r22_t

description: Library name: p21_10104_r22_t

source_name: Male Testis, 0.3 mg/kg/day FTCA, Animal r22


title: p21_10104_r18_t

description: Library name: p21_10104_r18_t

source_name: Male Testis, 0.1 mg/kg/day FTCA, Animal r18

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: p21_10104_r20_t

description: Library name: p21_10104_r20_t

source_name: Male Testis, 0.3 mg/kg/day FTCA, Animal r20

value: Male

value: Testis


title: p21_10104_r19_t

description: Library name: p21_10104_r19_t

source_name: Male Testis, 0.3 mg/kg/day FTCA, Animal r19


title: p21_10104_r17_t

description: Library name: p21_10104_r17_t

source_name: Male Testis, 0.1 mg/kg/day FTCA, Animal r17


title: p21_10104_r16_t

description: Library name: p21_10104_r16_t

source_name: Male Testis, 0.1 mg/kg/day FTCA, Animal r16


title: p21_10104_r14_t

description: Library name: p21_10104_r14_t

source_name: Male Testis, 0.1 mg/kg/day FTCA, Animal r14


title: p21_10104_r15_t

description: Library name: p21_10104_r15_t

source_name: Male Testis, 0.1 mg/kg/day FTCA, Animal r15


title: p21_10104_r10_t

description: Library name: p21_10104_r10_t

source_name: Male Testis, 0.01 mg/kg/day FTCA, Animal r10

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p21_10104_r12_t

description: Library name: p21_10104_r12_t

source_name: Male Testis, 0.01 mg/kg/day FTCA, Animal r12


title: p21_10104_r13_t

description: Library name: p21_10104_r13_t

source_name: Male Testis, 0.01 mg/kg/day FTCA, Animal r13


title: p21_10104_r11_t

description: Library name: p21_10104_r11_t

source_name: Male Testis, 0.01 mg/kg/day FTCA, Animal r11


title: p21_10104_r08_t

description: Library name: p21_10104_r08_t

source_name: Male Testis, Vehicle Control, Animal r08

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p21_10104_r09_t

description: Library name: p21_10104_r09_t

source_name: Male Testis, 0.01 mg/kg/day FTCA, Animal r09

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p21_10104_r07_t

description: Library name: p21_10104_r07_t

source_name: Male Testis, Vehicle Control, Animal r07

value: 8-10 weeks


title: p21_10104_r06_t

description: Library name: p21_10104_r06_t

source_name: Male Testis, Vehicle Control, Animal r06


title: p21_10104_r04_t

description: Library name: p21_10104_r04_t

source_name: Male Testis, Vehicle Control, Animal r04


title: p21_10104_r01_t

description: Library name: p21_10104_r01_t

source_name: Male Testis, Vehicle Control, Animal r01


title: p20_10104_r96_r

description: Library name: p20_10104_r96_r

source_name: Female Thyroid, 100 mg/kg/day FTCA, Animal r96

value: Female

value: Thyroid

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: p20_10104_r93_r

description: Library name: p20_10104_r93_r

source_name: Female Thyroid, 100 mg/kg/day FTCA, Animal r93

value: No Issue


title: p20_10104_r95_r

description: Library name: p20_10104_r95_r

source_name: Female Thyroid, 100 mg/kg/day FTCA, Animal r95


title: p20_10104_r94_r

description: Library name: p20_10104_r94_r

source_name: Female Thyroid, 100 mg/kg/day FTCA, Animal r94


title: p20_10104_r92_r

description: Library name: p20_10104_r92_r

source_name: Female Thyroid, 100 mg/kg/day FTCA, Animal r92


title: p20_10104_r91_r

description: Library name: p20_10104_r91_r

source_name: Female Thyroid, 30 mg/kg/day FTCA, Animal r91

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: p20_10104_r90_r

description: Library name: p20_10104_r90_r

source_name: Female Thyroid, 30 mg/kg/day FTCA, Animal r90


title: p20_10104_r89_r

description: Library name: p20_10104_r89_r

source_name: Female Thyroid, 30 mg/kg/day FTCA, Animal r89


title: p20_10104_r87_r

description: Library name: p20_10104_r87_r

source_name: Female Thyroid, 30 mg/kg/day FTCA, Animal r87


title: p20_10104_r86_r

description: Library name: p20_10104_r86_r

source_name: Female Thyroid, 10 mg/kg/day FTCA, Animal r86

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p20_10104_r84_r

description: Library name: p20_10104_r84_r

source_name: Female Thyroid, 10 mg/kg/day FTCA, Animal r84


title: p20_10104_r82_r

description: Library name: p20_10104_r82_r

source_name: Female Thyroid, 10 mg/kg/day FTCA, Animal r82


title: p20_10104_r81_r

description: Library name: p20_10104_r81_r

source_name: Female Thyroid, 3 mg/kg/day FTCA, Animal r81

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p20_10104_r83_r

description: Library name: p20_10104_r83_r

source_name: Female Thyroid, 10 mg/kg/day FTCA, Animal r83

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p20_10104_r80_r

description: Library name: p20_10104_r80_r

source_name: Female Thyroid, 3 mg/kg/day FTCA, Animal r80

value: Female

value: Thyroid

value: 8-10 weeks


title: p21_10104_r05_t

description: Library name: p21_10104_r05_t

source_name: Male Testis, Vehicle Control, Animal r05

value: Male

value: Testis

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p20_10104_r77_r

description: Library name: p20_10104_r77_r

source_name: Female Thyroid, 3 mg/kg/day FTCA, Animal r77

value: No Issue


title: p21_10104_r03_t

description: Library name: p21_10104_r03_t

source_name: Male Testis, Vehicle Control, Animal r03


title: p21_10104_r02_t

description: Library name: p21_10104_r02_t

source_name: Male Testis, Vehicle Control, Animal r02


title: p20_10104_r75_r

description: Library name: p20_10104_r75_r

source_name: Female Thyroid, 1 mg/kg/day FTCA, Animal r75

value: 1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: p20_10104_r74_r

description: Library name: p20_10104_r74_r

source_name: Female Thyroid, 1 mg/kg/day FTCA, Animal r74


title: p20_10104_r76_r

description: Library name: p20_10104_r76_r

source_name: Female Thyroid, 1 mg/kg/day FTCA, Animal r76

value: Outlier sample removed


title: p20_10104_r71_r

description: Library name: p20_10104_r71_r

source_name: Female Thyroid, 0.3 mg/kg/day FTCA, Animal r71

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p20_10104_r73_r

description: Library name: p20_10104_r73_r

source_name: Female Thyroid, 1 mg/kg/day FTCA, Animal r73

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p20_10104_r70_r

description: Library name: p20_10104_r70_r

source_name: Female Thyroid, 0.3 mg/kg/day FTCA, Animal r70

value: Female

value: Thyroid

value: 8-10 weeks


title: p20_10104_r72_r

description: Library name: p20_10104_r72_r

source_name: Female Thyroid, 1 mg/kg/day FTCA, Animal r72


title: p20_10104_r68_r

description: Library name: p20_10104_r68_r

source_name: Female Thyroid, 0.3 mg/kg/day FTCA, Animal r68


title: p20_10104_r65_r

description: Library name: p20_10104_r65_r

source_name: Female Thyroid, 0.1 mg/kg/day FTCA, Animal r65

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: p20_10104_r88_r

description: Library name: p20_10104_r88_r

source_name: Female Thyroid, 30 mg/kg/day FTCA, Animal r88

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7

value: No Issue


title: p20_10104_r63_r

description: Library name: p20_10104_r63_r

source_name: Female Thyroid, 0.1 mg/kg/day FTCA, Animal r63


title: p20_10104_r66_r

description: Library name: p20_10104_r66_r

source_name: Female Thyroid, 0.1 mg/kg/day FTCA, Animal r66


title: p20_10104_r69_r

description: Library name: p20_10104_r69_r

source_name: Female Thyroid, 0.3 mg/kg/day FTCA, Animal r69


title: p20_10104_r62_r

description: Library name: p20_10104_r62_r

source_name: Female Thyroid, 0.1 mg/kg/day FTCA, Animal r62


title: p20_10104_r61_r

description: Library name: p20_10104_r61_r

source_name: Female Thyroid, 0.01 mg/kg/day FTCA, Animal r61

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p20_10104_r64_r

description: Library name: p20_10104_r64_r

source_name: Female Thyroid, 0.1 mg/kg/day FTCA, Animal r64


title: p20_10104_r85_r

description: Library name: p20_10104_r85_r

source_name: Female Thyroid, 10 mg/kg/day FTCA, Animal r85

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p20_10104_r60_r

description: Library name: p20_10104_r60_r

source_name: Female Thyroid, 0.01 mg/kg/day FTCA, Animal r60

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p20_10104_r67_r

description: Library name: p20_10104_r67_r

source_name: Female Thyroid, 0.3 mg/kg/day FTCA, Animal r67

value: Female

value: Thyroid

value: 8-10 weeks

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p20_10104_r79_r

description: Library name: p20_10104_r79_r

source_name: Female Thyroid, 3 mg/kg/day FTCA, Animal r79

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p20_10104_r59_r

description: Library name: p20_10104_r59_r

source_name: Female Thyroid, 0.01 mg/kg/day FTCA, Animal r59

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: No Issue


title: p20_10104_r58_r

description: Library name: p20_10104_r58_r

source_name: Female Thyroid, 0.01 mg/kg/day FTCA, Animal r58

value: dose group:1


title: p20_10104_r57_r

description: Library name: p20_10104_r57_r

source_name: Female Thyroid, 0.01 mg/kg/day FTCA, Animal r57


title: p20_10104_r55_r

description: Library name: p20_10104_r55_r

source_name: Female Thyroid, Vehicle Control, Animal r55

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p20_10104_r56_r

description: Library name: p20_10104_r56_r

source_name: Female Thyroid, Vehicle Control, Animal r56

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: route of_exposure:Oral gavage


title: p20_10104_r78_r

description: Library name: p20_10104_r78_r

source_name: Female Thyroid, 3 mg/kg/day FTCA, Animal r78

value: Female

value: Thyroid

value: 8-10 weeks


title: p20_10104_r54_r

description: Library name: p20_10104_r54_r

source_name: Female Thyroid, Vehicle Control, Animal r54


title: p20_10104_r53_r

description: Library name: p20_10104_r53_r

source_name: Female Thyroid, Vehicle Control, Animal r53


title: p20_10104_r51_r

description: Library name: p20_10104_r51_r

source_name: Female Thyroid, Vehicle Control, Animal r51


title: p20_10104_r49_r

description: Library name: p20_10104_r49_r

source_name: Female Thyroid, Vehicle Control, Animal r49


title: p20_10104_r52_r

description: Library name: p20_10104_r52_r

source_name: Female Thyroid, Vehicle Control, Animal r52


title: p19_10104_r48_r

description: Library name: p19_10104_r48_r

source_name: Male Thyroid, 100 mg/kg/day FTCA, Animal r48

value: Male

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: p19_10104_r47_r

description: Library name: p19_10104_r47_r

source_name: Male Thyroid, 100 mg/kg/day FTCA, Animal r47


title: p19_10104_r46_r

description: Library name: p19_10104_r46_r

source_name: Male Thyroid, 100 mg/kg/day FTCA, Animal r46


title: p19_10104_r38_r

description: Library name: p19_10104_r38_r

source_name: Male Thyroid, 10 mg/kg/day FTCA, Animal r38

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6


title: p19_10104_r37_r

description: Library name: p19_10104_r37_r

source_name: Male Thyroid, 10 mg/kg/day FTCA, Animal r37

value: No Issue


title: p19_10104_r42_r

description: Library name: p19_10104_r42_r

source_name: Male Thyroid, 30 mg/kg/day FTCA, Animal r42

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: p19_10104_r43_r

description: Library name: p19_10104_r43_r

source_name: Male Thyroid, 30 mg/kg/day FTCA, Animal r43

value: Sprague Dawley


title: p19_10104_r39_r

description: Library name: p19_10104_r39_r

source_name: Male Thyroid, 30 mg/kg/day FTCA, Animal r39

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p19_10104_r45_r

description: Library name: p19_10104_r45_r

source_name: Male Thyroid, 100 mg/kg/day FTCA, Animal r45

value: route of_exposure:Oral gavage


title: p19_10104_r44_r

description: Library name: p19_10104_r44_r

source_name: Male Thyroid, 100 mg/kg/day FTCA, Animal r44


title: p19_10104_r36_r

description: Library name: p19_10104_r36_r

source_name: Male Thyroid, 10 mg/kg/day FTCA, Animal r36


title: p19_10104_r33_r

description: Library name: p19_10104_r33_r

source_name: Male Thyroid, 3 mg/kg/day FTCA, Animal r33

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p19_10104_r40_r

description: Library name: p19_10104_r40_r

source_name: Male Thyroid, 30 mg/kg/day FTCA, Animal r40

value: Male

value: Thyroid

value: 8-10 weeks


title: p19_10104_r41_r

description: Library name: p19_10104_r41_r

source_name: Male Thyroid, 30 mg/kg/day FTCA, Animal r41


title: p19_10104_r31_r

description: Library name: p19_10104_r31_r

source_name: Male Thyroid, 3 mg/kg/day FTCA, Animal r31


title: p19_10104_r34_r

description: Library name: p19_10104_r34_r

source_name: Male Thyroid, 10 mg/kg/day FTCA, Animal r34


title: p19_10104_r35_r

description: Library name: p19_10104_r35_r

source_name: Male Thyroid, 10 mg/kg/day FTCA, Animal r35


title: p19_10104_r29_r

description: Library name: p19_10104_r29_r

source_name: Male Thyroid, 3 mg/kg/day FTCA, Animal r29


title: p19_10104_r32_r

description: Library name: p19_10104_r32_r

source_name: Male Thyroid, 3 mg/kg/day FTCA, Animal r32


title: p19_10104_r27_r

description: Library name: p19_10104_r27_r

source_name: Male Thyroid, 1 mg/kg/day FTCA, Animal r27

value: 1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: p19_10104_r28_r

description: Library name: p19_10104_r28_r

source_name: Male Thyroid, 1 mg/kg/day FTCA, Animal r28


title: p20_10104_r50_r

description: Library name: p20_10104_r50_r

source_name: Female Thyroid, Vehicle Control, Animal r50

value: Female

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p19_10104_r26_r

description: Library name: p19_10104_r26_r

source_name: Male Thyroid, 1 mg/kg/day FTCA, Animal r26

value: No Issue


title: p19_10104_r30_r

description: Library name: p19_10104_r30_r

source_name: Male Thyroid, 3 mg/kg/day FTCA, Animal r30

value: Sprague Dawley


title: p19_10104_r25_r

description: Library name: p19_10104_r25_r

source_name: Male Thyroid, 1 mg/kg/day FTCA, Animal r25

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p19_10104_r24_r

description: Library name: p19_10104_r24_r

source_name: Male Thyroid, 1 mg/kg/day FTCA, Animal r24

value: route of_exposure:Oral gavage


title: p19_10104_r22_r

description: Library name: p19_10104_r22_r

source_name: Male Thyroid, 0.3 mg/kg/day FTCA, Animal r22

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p19_10104_r20_r

description: Library name: p19_10104_r20_r

source_name: Male Thyroid, 0.3 mg/kg/day FTCA, Animal r20

value: Male


title: p19_10104_r18_r

description: Library name: p19_10104_r18_r

source_name: Male Thyroid, 0.1 mg/kg/day FTCA, Animal r18

value: Thyroid

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2


title: p19_10104_r19_r

description: Library name: p19_10104_r19_r

source_name: Male Thyroid, 0.3 mg/kg/day FTCA, Animal r19

value: 8-10 weeks


title: p19_10104_r17_r

description: Library name: p19_10104_r17_r

source_name: Male Thyroid, 0.1 mg/kg/day FTCA, Animal r17


title: p19_10104_r14_r

description: Library name: p19_10104_r14_r

source_name: Male Thyroid, 0.1 mg/kg/day FTCA, Animal r14


title: p19_10104_r13_r

description: Library name: p19_10104_r13_r

source_name: Male Thyroid, 0.01 mg/kg/day FTCA, Animal r13

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p19_10104_r12_r

description: Library name: p19_10104_r12_r

source_name: Male Thyroid, 0.01 mg/kg/day FTCA, Animal r12


title: p19_10104_r11_r

description: Library name: p19_10104_r11_r

source_name: Male Thyroid, 0.01 mg/kg/day FTCA, Animal r11


title: p19_10104_r06_r

description: Library name: p19_10104_r06_r

source_name: Male Thyroid, Vehicle Control, Animal r06

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p19_10104_r07_r

description: Library name: p19_10104_r07_r

source_name: Male Thyroid, Vehicle Control, Animal r07

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)

value: No Issue


title: p19_10104_r09_r

description: Library name: p19_10104_r09_r

source_name: Male Thyroid, 0.01 mg/kg/day FTCA, Animal r09

value: route of_exposure:Oral gavage


title: p19_10104_r16_r

description: Library name: p19_10104_r16_r

source_name: Male Thyroid, 0.1 mg/kg/day FTCA, Animal r16


title: p19_10104_r01_r

description: Library name: p19_10104_r01_r

source_name: Male Thyroid, Vehicle Control, Animal r01


title: p19_10104_r05_r

description: Library name: p19_10104_r05_r

source_name: Male Thyroid, Vehicle Control, Animal r05


title: p19_10104_r23_r

description: Library name: p19_10104_r23_r

source_name: Male Thyroid, 0.3 mg/kg/day FTCA, Animal r23

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p19_10104_r08_r

description: Library name: p19_10104_r08_r

source_name: Male Thyroid, Vehicle Control, Animal r08

value: Male

value: Thyroid


title: p18_10104_r95_y

description: Library name: p18_10104_r95_y

source_name: Female Thymus, 100 mg/kg/day FTCA, Animal r95

value: Female

value: Thymus

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: p19_10104_r10_r

description: Library name: p19_10104_r10_r

source_name: Male Thyroid, 0.01 mg/kg/day FTCA, Animal r10

value: 8-10 weeks

value: 0.01 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.01 mg/kg/day

value: dose group:1


title: p19_10104_r21_r

description: Library name: p19_10104_r21_r

source_name: Male Thyroid, 0.3 mg/kg/day FTCA, Animal r21

value: Sprague Dawley

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p19_10104_r15_r

description: Library name: p19_10104_r15_r

source_name: Male Thyroid, 0.1 mg/kg/day FTCA, Animal r15

value: 0.1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.1 mg/kg/day

value: dose group:2

value: route of_exposure:Oral gavage

value: No Issue


title: p18_10104_r94_y

description: Library name: p18_10104_r94_y

source_name: Female Thymus, 100 mg/kg/day FTCA, Animal r94


title: p19_10104_r04_r

description: Library name: p19_10104_r04_r

source_name: Male Thyroid, Vehicle Control, Animal r04

value: Male

value: Thyroid

value: Corn oil control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: p19_10104_r02_r

description: Library name: p19_10104_r02_r

source_name: Male Thyroid, Vehicle Control, Animal r02


title: p18_10104_r96_y

description: Library name: p18_10104_r96_y

source_name: Female Thymus, 100 mg/kg/day FTCA, Animal r96

value: Female

value: Thymus

value: 100 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:100 mg/kg/day

value: dose group:8


title: p19_10104_r03_r

description: Library name: p19_10104_r03_r

source_name: Male Thyroid, Vehicle Control, Animal r03

value: Sprague Dawley

value: 8-10 weeks


title: p18_10104_r93_y

description: Library name: p18_10104_r93_y

source_name: Female Thymus, 100 mg/kg/day FTCA, Animal r93

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p18_10104_r90_y

description: Library name: p18_10104_r90_y

source_name: Female Thymus, 30 mg/kg/day FTCA, Animal r90

value: 30 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:30 mg/kg/day

value: dose group:7


title: p18_10104_r91_y

description: Library name: p18_10104_r91_y

source_name: Female Thymus, 30 mg/kg/day FTCA, Animal r91

value: route of_exposure:Oral gavage

value: No Issue


title: p18_10104_r89_y

description: Library name: p18_10104_r89_y

source_name: Female Thymus, 30 mg/kg/day FTCA, Animal r89


title: p18_10104_r92_y

description: Library name: p18_10104_r92_y

source_name: Female Thymus, 100 mg/kg/day FTCA, Animal r92


title: p18_10104_r87_y

description: Library name: p18_10104_r87_y

source_name: Female Thymus, 30 mg/kg/day FTCA, Animal r87


title: p18_10104_r88_y

description: Library name: p18_10104_r88_y

source_name: Female Thymus, 30 mg/kg/day FTCA, Animal r88


title: p18_10104_r73_y

description: Library name: p18_10104_r73_y

source_name: Female Thymus, 1 mg/kg/day FTCA, Animal r73

value: 1 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:1 mg/kg/day

value: dose group:4


title: p18_10104_r72_y

description: Library name: p18_10104_r72_y

source_name: Female Thymus, 1 mg/kg/day FTCA, Animal r72


title: p18_10104_r78_y

description: Library name: p18_10104_r78_y

source_name: Female Thymus, 3 mg/kg/day FTCA, Animal r78

value: 3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:3 mg/kg/day

value: dose group:5


title: p18_10104_r76_y

description: Library name: p18_10104_r76_y

source_name: Female Thymus, 1 mg/kg/day FTCA, Animal r76

value: Female

value: Thymus


title: p18_10104_r69_y

description: Library name: p18_10104_r69_y

source_name: Female Thymus, 0.3 mg/kg/day FTCA, Animal r69

value: 0.3 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:0.3 mg/kg/day

value: dose group:3


title: p18_10104_r86_y

description: Library name: p18_10104_r86_y

source_name: Female Thymus, 10 mg/kg/day FTCA, Animal r86

value: Sprague Dawley

value: 8-10 weeks

value: 10 mg/kg/day FTCA, 5-day repeat exposure, oral gavage

value: dose:10 mg/kg/day

value: dose group:6

value: chemical name:3:3 Fluorotelomer carboxylic acid (3:3 FTCA)


title: p18_10104_r85_y

description: Library name: p18_10104_r85_y

source_name: Female Thymus, 10 mg/kg/day FTCA, Animal r85

value: route of_exposure:Oral gavage

value: No Issue


title: p18_10104_r83_y

description: Library name: p18_10104_r83_y

source_name: Female Thymus, 10 mg/kg/day FTCA, Animal r83


title: p18_10104_r84_y

description: Library name: p18_10104_r84_y

source_name: Female Thymus, 10 mg/kg/day FTCA, Animal r84


title: p18_10104_r82_y

description: Library name: p18_10104_r82_y

source_name: Female Thymus, 10 mg/kg/day FTCA, Animal r82


title: p18_10104_r80_y

description: Library name: p18_10104_r80_y

source_name: Female Thymus, 3 mg/kg/day FTCA, Animal r80