title: Female Ovary, Vehicle Control, Animal r56

description: Library name: p22_10109_r56_o

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Ovary, Vehicle Control, Animal r51

status: Public on Jun 26 2025

type: SRA

city: RTP

first: Logan

middle: J

last: Everett

state: North Carolina

address: 109 T.W. Alexander Dr

department: Office of Research and Development

country: USA

institute: U.S. Environmental Protection Agency

description: Library name: p22_10109_r51_o

library_source: transcriptomic

data_processing:
Raw sequencing reads (FASTQ files) were aligned to known probe sequences listed in the TempO-Seq probe manifest using HISAT2 to compute a matrix of read counts for each probe in each sample.
Assembly: TempO-seq Rat S1500+ v1.2
Supplementary files format and content: Count table CSV files contain a row for each known probe and a column for each sample. Each cell contains the number of reads from a single cell uniquely aligned to a single probe sequence
Supplementary files format and content: Probe manifest CSV file contains a row for each known probe with the probe name, sequence, and target gene

molecule: total RNA

organism: Rattus norvegicus

source_name: Ovary

growth_protocol: Male and female Sprague Dawley (Crl:CD(SD), Charles River Laboratory) rats are purchased at 6 – 8 weeks of age. Upon receipt, the animals are placed on a standard, purified laboratory diet and reverse osmosis treated drinking water ad libitum. The specific brand and type of food and source of the water should be noted in Appendix II (Detailed Animal Study Report) of the individual assessment. After a 7- to 14-day quarantine and acclimation period, the animals are weighed and randomly assigned by weight to chemical exposure and control groups. Only clinically healthy animals are used in the study. The target age for initiating exposure is 8 - 10 weeks.

extract_protocol:
Treated and control animals are necropsied approximately 24 hours after the last exposure. Carbon dioxide asphyxiation is used as the method of euthanasia, with death confirmed by a secondary method such as exsanguination or cervical dislocation. The following tissues were dissected from each animal: kidney, liver, adrenal gland, brain, heart, lung, ovary (females), spleen, testis (males), thyroid, thymus, and uterus (females). Tissue samples were collected within ten minutes of termination. The left liver lobe, right kidney, left lung, both testis, uterus, heart, spleen, thymus and whole brain were sectioned into 5mm^3 pieces. Samples from these larger tissues were then individually divided into at least 3 cryovials. At least two of the samples from each tissue in each animal were preserved in RNAlater™ (Thermo Fisher Scientific) at 4°C overnight and then frozen at approximately -20°C for up to 3 weeks before transferring to approximately -80°C. At least one sample from each larger tissue is frozen immediately in liquid nitrogen and stored at approximately -80°C.   The smaller bilateral tissues: adrenal glands, thyroid gland, and ovaries (female) are placed into two cryovials and preserved in RNALater with the left side of the tissue or gland going into the first cryovial and the right side going into the second cryovial. The first tube of RNALater preserved tissue is submitted for sequencing. For each tissue undergoing transcriptomic analysis, total RNA is extracted from one of the aliquots stored in RNAlater™.
The isolated total RNA is used to perform targeted RNA sequencing (RNA-seq) using the BioSpyder TempO-Seq rat S1500+ assay (v1.2) according to manufacturer’s instructions. No specific RNA purity or integrity criteria are applied to the RNA samples as the TempO-Seq assay has been designed to provide high quality gene expression measurements on whole cell lysates, purified RNA, and formalin-fixed paraffin embedded tissue.

treatment_protocol: For oral gavage studies, at least four male and four female rats per dose group receive the vehicle alone or test article in vehicle via gavage (5 or 10 ml/kg) for five days. Animals are weighed daily prior to administration and are observed twice daily, once during administration and once in the late afternoon, at least six hours apart, for assessment of moribundity and mortality. Formal clinical observations are performed on the first day post-dosing and prior to necropsy. Moribund animals or animals exhibiting overt clinical toxicity are removed from the study. The temperature in the experimental animal room is maintained at a target of 22°C (± 3°C) with a relative humidity that is ideally between 50-60% but is at least 30% and preferably not to exceed 70% other than during room cleaning. Lighting is artificial with a sequence of 12 hours light, 12 hours dark. Animals are housed individually or caged in small groups of no more than three animals of the same sex in accordance with local institutional animal care and use requirements.

tag: Sex

value: Female

tag: tissue

value: Ovary

tag: strain

value: Sprague Dawley

tag: age

value: 8-10 weeks

tag: treatment

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

tag: sample qc_issue

value: No Issue


title: Female Ovary, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p22_10109_r58_o

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Testis, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p21_10109_r48_t

source_name: Testis

value: Male

value: Testis

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Testis, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p21_10109_r38_t

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Ovary, Vehicle Control, Animal r53

description: Library name: p22_10109_r53_o

value: Female

value: Ovary

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Testis, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p21_10109_r39_t

value: Sprague Dawley

value: 8-10 weeks

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage

value: No Issue


title: Male Testis, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p21_10109_r46_t

value: Male

value: Testis

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Testis, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p21_10109_r47_t


title: Female Ovary, Vehicle Control, Animal r49

description: Library name: p22_10109_r49_o

value: Female

value: Ovary


title: Male Testis, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p21_10109_r31_t

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Testis, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p21_10109_r36_t

value: Sprague Dawley

value: 8-10 weeks

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Testis, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p21_10109_r29_t

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Testis, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p21_10109_r28_t

value: Male

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4

value: No Issue


title: Male Testis, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p21_10109_r40_t

value: Testis

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Ovary, Vehicle Control, Animal r54

description: Library name: p22_10109_r54_o

value: Female

value: Ovary

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Testis, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p21_10109_r44_t

value: Sprague Dawley

value: 8-10 weeks

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: Outlier sample removed


title: Male Testis, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p21_10109_r37_t

value: Male

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Testis, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p21_10109_r43_t

value: Testis

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: No Issue


title: Male Testis, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p21_10109_r34_t

value: Sprague Dawley


title: Male Testis, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p21_10109_r30_t

value: 8-10 weeks

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Testis, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p21_10109_r27_t

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Testis, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p21_10109_r26_t

value: Male


title: Male Testis, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p21_10109_r25_t


title: Male Testis, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p21_10109_r23_t

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Testis, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p21_10109_r22_t

value: Testis

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Testis, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p21_10109_r24_t


title: Male Testis, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p21_10109_r21_t


title: Male Testis, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p21_10109_r35_t

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Testis, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p21_10109_r20_t

value: Sprague Dawley

value: 8-10 weeks

value: No Issue


title: Male Testis, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p21_10109_r19_t


title: Male Testis, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p21_10109_r32_t

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Testis, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p21_10109_r33_t


title: Male Testis, Vehicle Control, Animal r08

description: Library name: p21_10109_r08_t

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Testis, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p21_10109_r12_t

value: Male

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Testis, Vehicle Control, Animal r07

description: Library name: p21_10109_r07_t

value: Testis

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Testis, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p21_10109_r09_t


title: Female Thyroid, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p20_10109_r94_r

source_name: Thyroid

value: Female

value: Thyroid

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Testis, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p21_10109_r14_t

value: Sprague Dawley

value: 8-10 weeks

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2

value: No Issue


title: Male Testis, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p21_10109_r16_t

value: Male


title: Male Testis, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p21_10109_r17_t


title: Male Testis, Vehicle Control, Animal r06

description: Library name: p21_10109_r06_t

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Testis, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p21_10109_r11_t

value: Testis

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Testis, Vehicle Control, Animal r04

description: Library name: p21_10109_r04_t

value: route of_exposure:Oral gavage


title: Male Testis, Vehicle Control, Animal r05

description: Library name: p21_10109_r05_t


title: Male Testis, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p21_10109_r18_t


title: Male Testis, Vehicle Control, Animal r01

description: Library name: p21_10109_r01_t


title: Male Testis, Vehicle Control, Animal r02

description: Library name: p21_10109_r02_t


title: Male Testis, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p21_10109_r15_t


title: Female Thyroid, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p20_10109_r93_r

value: Female

value: Thyroid

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Testis, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p21_10109_r13_t

value: Sprague Dawley

value: 8-10 weeks


title: Female Thyroid, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p20_10109_r92_r

value: No Issue


title: Male Testis, Vehicle Control, Animal r03

description: Library name: p21_10109_r03_t

value: Male

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage


title: Female Thyroid, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p20_10109_r91_r

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Thyroid, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p20_10109_r95_r


title: Female Thyroid, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p20_10109_r96_r


title: Male Testis, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p21_10109_r10_t

value: Testis

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day


title: Female Thyroid, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p20_10109_r86_r

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Thyroid, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p20_10109_r89_r

value: Female

value: Thyroid


title: Female Thyroid, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p20_10109_r85_r

value: Sprague Dawley

value: 8-10 weeks


title: Female Thyroid, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p20_10109_r88_r

value: No Issue


title: Female Thyroid, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p20_10109_r81_r

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Thyroid, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p20_10109_r80_r


title: Female Thyroid, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p20_10109_r73_r

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Thyroid, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p20_10109_r83_r


title: Female Thyroid, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p20_10109_r84_r


title: Female Thyroid, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p20_10109_r78_r


title: Female Thyroid, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p20_10109_r82_r


title: Female Thyroid, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p20_10109_r79_r


title: Female Thyroid, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p20_10109_r76_r


title: Female Thyroid, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p20_10109_r90_r

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Thyroid, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p20_10109_r70_r

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Thyroid, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p20_10109_r72_r

value: Female

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Thyroid, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p20_10109_r87_r

value: Thyroid

value: Sprague Dawley

value: 8-10 weeks


title: Female Thyroid, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p20_10109_r75_r

value: No Issue


title: Female Thyroid, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p20_10109_r67_r


title: Female Thyroid, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p20_10109_r74_r


title: Female Thyroid, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p20_10109_r77_r

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Thyroid, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p20_10109_r71_r


title: Female Thyroid, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p20_10109_r68_r


title: Female Thyroid, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p20_10109_r66_r

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Thyroid, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p20_10109_r59_r

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Thyroid, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p20_10109_r61_r


title: Female Thyroid, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p20_10109_r58_r


title: Female Thyroid, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p20_10109_r57_r


title: Female Thyroid, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p20_10109_r69_r

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Thyroid, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p20_10109_r65_r

value: Female

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Thyroid, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p20_10109_r63_r

value: Thyroid

value: Sprague Dawley

value: 8-10 weeks


title: Female Thyroid, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p20_10109_r62_r

value: No Issue


title: Female Thyroid, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p20_10109_r64_r


title: Female Thyroid, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p20_10109_r60_r


title: Female Thyroid, Vehicle Control, Animal r56

description: Library name: p20_10109_r56_r

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Thyroid, Vehicle Control, Animal r55

description: Library name: p20_10109_r55_r


title: Female Thyroid, Vehicle Control, Animal r54

description: Library name: p20_10109_r54_r


title: Female Thyroid, Vehicle Control, Animal r53

description: Library name: p20_10109_r53_r


title: Male Thyroid, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p19_10109_r48_r

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Thyroid, Vehicle Control, Animal r50

description: Library name: p20_10109_r50_r


title: Male Thyroid, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p19_10109_r47_r


title: Female Thyroid, Vehicle Control, Animal r51

description: Library name: p20_10109_r51_r


title: Male Thyroid, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p19_10109_r38_r

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Thyroid, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p19_10109_r44_r


title: Male Thyroid, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p19_10109_r40_r

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Thyroid, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p19_10109_r37_r

value: Thyroid

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Thyroid, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p19_10109_r31_r

value: Sprague Dawley

value: 8-10 weeks

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5

value: No Issue


title: Male Thyroid, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p19_10109_r34_r

value: Male


title: Male Thyroid, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p19_10109_r33_r


title: Male Thyroid, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p19_10109_r35_r


title: Male Thyroid, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p19_10109_r28_r

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Thyroid, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p19_10109_r41_r


title: Male Thyroid, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p19_10109_r43_r


title: Male Thyroid, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p19_10109_r27_r


title: Male Thyroid, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p19_10109_r42_r


title: Male Thyroid, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p19_10109_r39_r

value: Outlier sample removed


title: Male Thyroid, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p19_10109_r36_r

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Thyroid, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p19_10109_r32_r

value: Thyroid


title: Male Thyroid, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p19_10109_r25_r

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Thyroid, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p19_10109_r30_r

value: route of_exposure:Oral gavage


title: Male Thyroid, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p19_10109_r29_r

value: Sprague Dawley


title: Female Thyroid, Vehicle Control, Animal r49

description: Library name: p20_10109_r49_r

value: Female

value: 8-10 weeks

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thyroid, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p19_10109_r24_r

value: Male

value: No Issue


title: Male Thyroid, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p19_10109_r22_r

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Thyroid, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p19_10109_r26_r

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Thyroid, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p19_10109_r21_r

value: Thyroid


title: Male Thyroid, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p19_10109_r18_r

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Thyroid, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p19_10109_r15_r

value: Sprague Dawley

value: 8-10 weeks

value: route of_exposure:Oral gavage


title: Male Thyroid, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p19_10109_r23_r


title: Female Thyroid, Vehicle Control, Animal r52

description: Library name: p20_10109_r52_r

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thyroid, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p19_10109_r16_r

value: Male

value: No Issue


title: Male Thyroid, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p19_10109_r17_r


title: Male Thyroid, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p19_10109_r46_r

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Thyroid, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p19_10109_r14_r

value: Thyroid


title: Male Thyroid, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p19_10109_r09_r

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Thyroid, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p19_10109_r19_r

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Thyroid, Vehicle Control, Animal r04

description: Library name: p19_10109_r04_r

value: Sprague Dawley

value: 8-10 weeks

value: route of_exposure:Oral gavage


title: Male Thyroid, Vehicle Control, Animal r03

description: Library name: p19_10109_r03_r

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thyroid, Vehicle Control, Animal r02

description: Library name: p19_10109_r02_r

value: Male

value: No Issue


title: Male Thyroid, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p19_10109_r11_r


title: Male Thyroid, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p19_10109_r13_r


title: Female Thymus, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p18_10109_r94_y

source_name: Thymus

value: Female

value: Thymus

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Thyroid, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p19_10109_r10_r

value: Thyroid

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Thymus, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p18_10109_r91_y

value: Sprague Dawley

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Thymus, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p18_10109_r89_y

value: 8-10 weeks

value: route of_exposure:Oral gavage


title: Male Thyroid, Vehicle Control, Animal r08

description: Library name: p19_10109_r08_r

value: Male

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: No Issue


title: Female Thymus, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p18_10109_r88_y

value: Female

value: Thymus


title: Female Thymus, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p18_10109_r85_y

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Thymus, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p18_10109_r84_y

value: Sprague Dawley


title: Male Thyroid, Vehicle Control, Animal r05

description: Library name: p19_10109_r05_r

value: Thyroid


title: Male Thyroid, Vehicle Control, Animal r07

description: Library name: p19_10109_r07_r


title: Female Thymus, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p18_10109_r81_y

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Thyroid, Vehicle Control, Animal r06

description: Library name: p19_10109_r06_r

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Thyroid, Vehicle Control, Animal r01

description: Library name: p19_10109_r01_r

value: Male

value: route of_exposure:Oral gavage


title: Female Thymus, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p18_10109_r77_y


title: Female Thymus, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p18_10109_r78_y


title: Female Thymus, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p18_10109_r76_y

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Thymus, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p18_10109_r75_y

value: Female

value: No Issue


title: Female Thymus, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p18_10109_r74_y

value: Thymus


title: Female Thymus, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p18_10109_r96_y

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Thymus, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p18_10109_r93_y

value: Sprague Dawley


title: Female Thymus, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p18_10109_r70_y

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Thymus, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p18_10109_r92_y

value: 8-10 weeks


title: Female Thymus, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p18_10109_r64_y

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Thymus, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p18_10109_r63_y

value: route of_exposure:Oral gavage


title: Female Thymus, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p18_10109_r66_y


title: Female Thymus, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p18_10109_r61_y

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Thyroid, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p19_10109_r20_r

value: Male

value: Thyroid

value: No Issue


title: Female Thymus, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p18_10109_r58_y

value: Female

value: Thymus


title: Female Thymus, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p18_10109_r90_y

value: Sprague Dawley

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Thymus, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p18_10109_r59_y

value: 8-10 weeks


title: Male Thyroid, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p19_10109_r12_r


title: Female Thymus, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p18_10109_r87_y


title: Female Thymus, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p18_10109_r86_y

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Thymus, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p18_10109_r83_y

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Thymus, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p18_10109_r57_y

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day


title: Female Thymus, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p18_10109_r82_y


title: Female Thymus, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p18_10109_r80_y

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Thymus, Vehicle Control, Animal r55

description: Library name: p18_10109_r55_y

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: No Issue


title: Female Thymus, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p18_10109_r95_y

value: Thymus

value: Sprague Dawley

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Thymus, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p18_10109_r79_y

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Thymus, Vehicle Control, Animal r53

description: Library name: p18_10109_r53_y

value: route of_exposure:Oral gavage


title: Female Thymus, Vehicle Control, Animal r50

description: Library name: p18_10109_r50_y


title: Female Thymus, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p18_10109_r72_y

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Thymus, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p18_10109_r73_y


title: Female Thymus, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p18_10109_r71_y

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Thymus, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p17_10109_r48_y

value: Male


title: Female Thymus, Vehicle Control, Animal r54

description: Library name: p18_10109_r54_y

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thymus, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p17_10109_r40_y

value: Thymus

value: Sprague Dawley

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: No Issue


title: Male Thymus, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p17_10109_r41_y

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Thymus, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p18_10109_r68_y

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Male Thymus, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p17_10109_r39_y


title: Male Thymus, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p17_10109_r36_y

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Thymus, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p18_10109_r62_y

value: Female

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Thymus, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p18_10109_r65_y

value: Thymus


title: Male Thymus, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p17_10109_r33_y

value: Male

value: Sprague Dawley

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Thymus, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p17_10109_r34_y

value: 8-10 weeks

value: No Issue


title: Female Thymus, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p18_10109_r60_y

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Thymus, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p17_10109_r32_y


title: Male Thymus, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p17_10109_r29_y

value: < 50% reads aligned


title: Female Thymus, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p18_10109_r69_y

value: Female

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Thymus, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p17_10109_r26_y

value: Male

value: Thymus

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Thymus, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p17_10109_r25_y

value: Sprague Dawley

value: 8-10 weeks


title: Male Thymus, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p17_10109_r27_y

value: No Issue


title: Female Thymus, Vehicle Control, Animal r56

description: Library name: p18_10109_r56_y

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thymus, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p17_10109_r23_y

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Thymus, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p18_10109_r67_y

value: Female


title: Female Thymus, Vehicle Control, Animal r52

description: Library name: p18_10109_r52_y


title: Male Thymus, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p17_10109_r20_y

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Female Thymus, Vehicle Control, Animal r49

description: Library name: p18_10109_r49_y


title: Female Thymus, Vehicle Control, Animal r51

description: Library name: p18_10109_r51_y


title: Male Thymus, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p17_10109_r17_y

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Thymus, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p17_10109_r15_y

value: Male

value: Thymus


title: Male Thymus, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p17_10109_r47_y

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Thymus, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p17_10109_r46_y

value: Sprague Dawley

value: 8-10 weeks


title: Male Thymus, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p17_10109_r44_y

value: No Issue


title: Male Thymus, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p17_10109_r43_y

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Thymus, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p17_10109_r24_y

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Thymus, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p17_10109_r14_y

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Thymus, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p17_10109_r38_y

value: Male

value: Thymus

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Thymus, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p17_10109_r42_y

value: Sprague Dawley

value: 8-10 weeks

value: No Issue


title: Male Thymus, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p17_10109_r37_y


title: Male Thymus, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p17_10109_r11_y

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Thymus, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p17_10109_r10_y


title: Male Thymus, Vehicle Control, Animal r08

description: Library name: p17_10109_r08_y

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thymus, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p17_10109_r35_y

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Thymus, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p17_10109_r31_y

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Thymus, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p17_10109_r30_y

value: Male

value: Thymus


title: Male Thymus, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p17_10109_r28_y

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Thymus, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p17_10109_r22_y

value: Sprague Dawley

value: 8-10 weeks

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3

value: No Issue


title: Male Thymus, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p17_10109_r19_y


title: Male Thymus, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p17_10109_r21_y


title: Female Spleen, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p16_10109_r94_s

source_name: Spleen

value: Female

value: Spleen

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Spleen, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p16_10109_r91_s

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Thymus, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p17_10109_r16_y

value: Male

value: Thymus

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Thymus, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p17_10109_r12_y

value: Sprague Dawley

value: 8-10 weeks

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Thymus, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p17_10109_r18_y

value: No Issue


title: Male Thymus, Vehicle Control, Animal r06

description: Library name: p17_10109_r06_y

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Thymus, Vehicle Control, Animal r05

description: Library name: p17_10109_r05_y


title: Male Thymus, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p17_10109_r13_y


title: Male Thymus, Vehicle Control, Animal r07

description: Library name: p17_10109_r07_y


title: Male Thymus, Vehicle Control, Animal r04

description: Library name: p17_10109_r04_y


title: Female Spleen, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p16_10109_r96_s

value: Female

value: Spleen

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Thymus, Vehicle Control, Animal r02

description: Library name: p17_10109_r02_y

value: Male

value: Thymus

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Spleen, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p16_10109_r82_s

value: Sprague Dawley

value: 8-10 weeks

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Spleen, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p16_10109_r93_s

value: No Issue


title: Female Spleen, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p16_10109_r90_s

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Spleen, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p16_10109_r92_s

value: Female

value: Spleen


title: Female Spleen, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p16_10109_r89_s


title: Female Spleen, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p16_10109_r86_s


title: Female Spleen, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p16_10109_r87_s


title: Male Thymus, Vehicle Control, Animal r03

description: Library name: p17_10109_r03_y

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Spleen, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p16_10109_r85_s


title: Male Thymus, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p17_10109_r09_y

value: Male

value: Thymus

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Spleen, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p16_10109_r95_s

value: Sprague Dawley

value: 8-10 weeks

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Spleen, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p16_10109_r79_s

value: Female

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5

value: No Issue


title: Female Spleen, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p16_10109_r71_s

value: Spleen

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Spleen, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p16_10109_r74_s

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Spleen, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p16_10109_r84_s

value: Sprague Dawley

value: 8-10 weeks

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Spleen, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p16_10109_r70_s

value: Female

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Spleen, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p16_10109_r68_s


title: Female Spleen, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p16_10109_r83_s


title: Female Spleen, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p16_10109_r80_s

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Spleen, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p16_10109_r78_s

value: Spleen

value: No Issue


title: Female Spleen, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p16_10109_r66_s

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Spleen, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p16_10109_r81_s


title: Female Spleen, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p16_10109_r75_s

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Spleen, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p16_10109_r64_s

value: Sprague Dawley

value: 8-10 weeks


title: Female Spleen, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p16_10109_r73_s


title: Female Spleen, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p16_10109_r77_s


title: Female Spleen, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p16_10109_r67_s

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Spleen, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p16_10109_r60_s

value: Female

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Female Spleen, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p16_10109_r76_s

value: Spleen

value: No Issue


title: Female Spleen, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p16_10109_r63_s

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Spleen, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p16_10109_r62_s


title: Female Spleen, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p16_10109_r61_s


title: Female Spleen, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p16_10109_r65_s


title: Female Spleen, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p16_10109_r72_s

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Spleen, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p16_10109_r58_s

value: Sprague Dawley

value: 8-10 weeks


title: Female Spleen, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p16_10109_r69_s

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Spleen, Vehicle Control, Animal r51

description: Library name: p16_10109_r51_s

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Spleen, Vehicle Control, Animal r49

description: Library name: p16_10109_r49_s

value: Spleen

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Spleen, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p15_10109_r47_s

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: No Issue


title: Male Spleen, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p15_10109_r46_s

value: Sprague Dawley


title: Female Spleen, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p16_10109_r57_s

value: 8-10 weeks

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Spleen, Vehicle Control, Animal r56

description: Library name: p16_10109_r56_s

value: Female


title: Female Spleen, Vehicle Control, Animal r55

description: Library name: p16_10109_r55_s

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage


title: Male Spleen, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p15_10109_r41_s

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Spleen, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p15_10109_r40_s

value: Spleen

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Spleen, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p15_10109_r39_s

value: Male

value: route of_exposure:Oral gavage


title: Male Spleen, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p15_10109_r37_s

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Spleen, Vehicle Control, Animal r52

description: Library name: p16_10109_r52_s

value: Sprague Dawley

value: dose:0 mg/kg/day

value: dose group:0

value: No Issue


title: Male Spleen, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p15_10109_r34_s

value: 8-10 weeks


title: Female Spleen, Vehicle Control, Animal r54

description: Library name: p16_10109_r54_s

value: Female


title: Male Spleen, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p15_10109_r35_s


title: Male Spleen, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p15_10109_r36_s


title: Male Spleen, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p15_10109_r32_s

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Spleen, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p15_10109_r38_s


title: Female Spleen, Vehicle Control, Animal r50

description: Library name: p16_10109_r50_s

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage


title: Male Spleen, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p15_10109_r31_s

value: Spleen

value: Outlier sample removed


title: Male Spleen, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p15_10109_r48_s

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Spleen, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p15_10109_r43_s

value: Sprague Dawley

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: route of_exposure:Oral gavage


title: Female Spleen, Vehicle Control, Animal r53

description: Library name: p16_10109_r53_s

value: Female

value: 8-10 weeks

value: dose:0 mg/kg/day

value: dose group:0

value: No Issue


title: Male Spleen, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p15_10109_r33_s

value: Spleen

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Spleen, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p15_10109_r28_s

value: Male

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Spleen, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p15_10109_r42_s

value: Sprague Dawley

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Spleen, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p15_10109_r27_s

value: route of_exposure:Oral gavage


title: Male Spleen, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p15_10109_r29_s


title: Male Spleen, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p15_10109_r26_s


title: Male Spleen, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p15_10109_r24_s


title: Male Spleen, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p15_10109_r23_s

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Spleen, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p15_10109_r21_s

value: 8-10 weeks


title: Male Spleen, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p15_10109_r20_s

value: No Issue


title: Male Spleen, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p15_10109_r14_s

value: Spleen

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Spleen, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p15_10109_r16_s

value: Male


title: Male Spleen, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p15_10109_r17_s


title: Male Spleen, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p15_10109_r22_s


title: Male Spleen, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p15_10109_r19_s


title: Male Spleen, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p15_10109_r13_s

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Spleen, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p16_10109_r59_s

value: Female

value: Sprague Dawley


title: Male Spleen, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p15_10109_r12_s

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Spleen, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p15_10109_r25_s

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4

value: route of_exposure:Oral gavage


title: Male Spleen, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p15_10109_r18_s

value: 8-10 weeks


title: Male Spleen, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p15_10109_r11_s

value: No Issue


title: Male Spleen, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p15_10109_r10_s

value: Spleen


title: Male Spleen, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p15_10109_r30_s

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Spleen, Vehicle Control, Animal r07

description: Library name: p15_10109_r07_s

value: Male

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Spleen, Vehicle Control, Animal r08

description: Library name: p15_10109_r08_s


title: Male Spleen, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p15_10109_r15_s

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Spleen, Vehicle Control, Animal r06

description: Library name: p15_10109_r06_s

value: Sprague Dawley

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Spleen, Vehicle Control, Animal r05

description: Library name: p15_10109_r05_s


title: Male Spleen, Vehicle Control, Animal r02

description: Library name: p15_10109_r02_s


title: Male Spleen, Vehicle Control, Animal r03

description: Library name: p15_10109_r03_s


title: Male Spleen, Vehicle Control, Animal r01

description: Library name: p15_10109_r01_s


title: Male Spleen, Vehicle Control, Animal r04

description: Library name: p15_10109_r04_s


title: Female Lung, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p14_10109_r95_n

source_name: Lung

value: Female

value: Lung

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Lung, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p14_10109_r94_n

value: 8-10 weeks

value: route of_exposure:Oral gavage

value: No Issue


title: Female Lung, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p14_10109_r93_n


title: Female Lung, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p14_10109_r89_n

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Lung, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p14_10109_r90_n


title: Female Lung, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p14_10109_r91_n


title: Female Lung, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p14_10109_r86_n

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Lung, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p14_10109_r87_n


title: Female Lung, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p14_10109_r81_n

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Lung, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p14_10109_r79_n

value: Female

value: Sprague Dawley

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Lung, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p14_10109_r80_n

value: Lung


title: Male Thymus, Vehicle Control, Animal r01

description: Library name: p17_10109_r01_y

value: Male

value: Thymus

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Lung, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p14_10109_r84_n

value: 8-10 weeks

value: route of_exposure:Oral gavage

value: No Issue


title: Female Lung, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p14_10109_r78_n


title: Female Lung, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p14_10109_r77_n


title: Female Lung, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p14_10109_r83_n

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day


title: Male Spleen, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p15_10109_r09_s

value: Spleen

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Lung, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p14_10109_r76_n

value: Female

value: Sprague Dawley

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Lung, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p14_10109_r73_n

value: Lung

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Lung, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p14_10109_r88_n

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Lung, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p14_10109_r96_n

value: 8-10 weeks

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: route of_exposure:Oral gavage

value: No Issue


title: Female Lung, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p14_10109_r92_n


title: Female Lung, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p14_10109_r72_n


title: Female Lung, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p14_10109_r74_n


title: Female Lung, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p14_10109_r70_n

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Lung, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p14_10109_r68_n

value: Female

value: Sprague Dawley


title: Female Lung, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p14_10109_r85_n

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Female Lung, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p14_10109_r69_n

value: Lung

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Lung, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p14_10109_r82_n


title: Female Lung, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p14_10109_r66_n

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Lung, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p14_10109_r67_n

value: 8-10 weeks


title: Female Lung, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p14_10109_r65_n


title: Female Lung, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p14_10109_r64_n


title: Female Lung, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p14_10109_r75_n

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Lung, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p14_10109_r63_n

value: route of_exposure:Oral gavage

value: No Issue


title: Female Lung, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p14_10109_r62_n


title: Female Lung, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p14_10109_r71_n

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Lung, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p14_10109_r61_n

value: Female

value: Sprague Dawley

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Lung, Vehicle Control, Animal r53

description: Library name: p14_10109_r53_n

value: Lung

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Lung, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p13_10109_r48_n

value: Male

value: 8-10 weeks

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Lung, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p14_10109_r60_n

value: route of_exposure:Oral gavage

value: No Issue


title: Female Lung, Vehicle Control, Animal r50

description: Library name: p14_10109_r50_n

value: Female


title: Female Lung, Vehicle Control, Animal r52

description: Library name: p14_10109_r52_n

value: Sprague Dawley


title: Female Lung, Vehicle Control, Animal r56

description: Library name: p14_10109_r56_n


title: Female Lung, Vehicle Control, Animal r54

description: Library name: p14_10109_r54_n


title: Female Lung, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p14_10109_r57_n

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Female Lung, Vehicle Control, Animal r49

description: Library name: p14_10109_r49_n


title: Female Lung, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p14_10109_r58_n

value: dose:0.05 mg/kg/day


title: Male Lung, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p13_10109_r46_n


title: Female Lung, Vehicle Control, Animal r51

description: Library name: p14_10109_r51_n


title: Female Lung, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p14_10109_r59_n

value: dose group:1


title: Male Lung, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p13_10109_r47_n

value: Lung


title: Male Lung, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p13_10109_r44_n


title: Male Lung, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p13_10109_r43_n

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Lung, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p13_10109_r42_n

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Lung, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p13_10109_r41_n

value: Male


title: Male Lung, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p13_10109_r40_n

value: 8-10 weeks


title: Male Lung, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p13_10109_r38_n

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Lung, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p13_10109_r37_n

value: route of_exposure:Oral gavage


title: Male Lung, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p13_10109_r36_n

value: No Issue


title: Female Lung, Vehicle Control, Animal r55

description: Library name: p14_10109_r55_n

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Lung, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p13_10109_r35_n

value: Sprague Dawley


title: Female Spleen, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p16_10109_r88_s

value: Spleen


title: Male Lung, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p13_10109_r34_n

value: Lung


title: Male Lung, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p13_10109_r33_n

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Lung, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p13_10109_r30_n

value: Male

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Lung, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p13_10109_r31_n

value: 8-10 weeks


title: Male Lung, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p13_10109_r28_n

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Lung, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p13_10109_r25_n

value: route of_exposure:Oral gavage

value: No Issue


title: Male Lung, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p13_10109_r29_n


title: Male Lung, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p13_10109_r20_n

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Lung, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p13_10109_r32_n

value: Sprague Dawley


title: Male Lung, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p13_10109_r18_n

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Lung, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p13_10109_r27_n

value: Lung


title: Male Lung, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p13_10109_r24_n


title: Male Lung, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p13_10109_r21_n


title: Male Lung, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p13_10109_r23_n


title: Male Lung, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p13_10109_r39_n

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Lung, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p13_10109_r17_n

value: Male

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Lung, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p13_10109_r16_n


title: Male Lung, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p13_10109_r14_n


title: Male Lung, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p13_10109_r13_n

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Lung, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p13_10109_r11_n

value: route of_exposure:Oral gavage

value: No Issue


title: Male Lung, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p13_10109_r15_n


title: Male Lung, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p13_10109_r10_n


title: Male Lung, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p13_10109_r09_n


title: Male Lung, Vehicle Control, Animal r08

description: Library name: p13_10109_r08_n

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Lung, Vehicle Control, Animal r07

description: Library name: p13_10109_r07_n

value: Sprague Dawley


title: Male Lung, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p13_10109_r26_n

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Male Lung, Vehicle Control, Animal r06

description: Library name: p13_10109_r06_n

value: Lung


title: Male Lung, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p13_10109_r22_n

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Lung, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p13_10109_r19_n

value: Male

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Lung, Vehicle Control, Animal r05

description: Library name: p13_10109_r05_n


title: Male Lung, Vehicle Control, Animal r03

description: Library name: p13_10109_r03_n


title: Male Lung, Vehicle Control, Animal r02

description: Library name: p13_10109_r02_n


title: Male Lung, Vehicle Control, Animal r01

description: Library name: p13_10109_r01_n

value: Outlier sample removed


title: Female Liver, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p12_10109_r95_l

source_name: Liver

value: Female

value: Liver

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8

value: route of_exposure:Oral gavage


title: Female Liver, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p12_10109_r96_l

value: Sprague Dawley

value: No Issue


title: Female Liver, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p12_10109_r94_l


title: Female Liver, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p12_10109_r93_l


title: Female Liver, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p12_10109_r89_l

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Liver, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p12_10109_r88_l


title: Male Lung, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p13_10109_r12_n

value: Lung

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Liver, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p12_10109_r85_l

value: 8-10 weeks

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Liver, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p12_10109_r87_l

value: Female

value: Liver


title: Female Liver, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p12_10109_r86_l

value: route of_exposure:Oral gavage


title: Male Spleen, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p15_10109_r44_s

value: Male

value: Spleen

value: Sprague Dawley

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Liver, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p12_10109_r83_l

value: No Issue


title: Female Liver, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p12_10109_r82_l


title: Female Liver, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p12_10109_r90_l

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Liver, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p12_10109_r84_l

value: 8-10 weeks

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Female Liver, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p12_10109_r80_l

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Liver, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p12_10109_r79_l

value: Female

value: Liver

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Liver, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p12_10109_r78_l

value: route of_exposure:Oral gavage


title: Female Liver, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p12_10109_r81_l

value: Sprague Dawley


title: Female Liver, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p12_10109_r92_l

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage


title: Male Lung, Vehicle Control, Animal r04

description: Library name: p13_10109_r04_n

value: Male

value: Lung

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Liver, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p12_10109_r77_l

value: No Issue


title: Female Liver, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p12_10109_r74_l

value: 8-10 weeks

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Liver, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p12_10109_r76_l


title: Female Liver, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p12_10109_r73_l


title: Female Liver, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p12_10109_r70_l

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Liver, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p12_10109_r72_l

value: Female

value: Liver

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Liver, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p12_10109_r69_l

value: Sprague Dawley

value: route of_exposure:Oral gavage


title: Female Liver, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p12_10109_r67_l


title: Female Liver, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p12_10109_r71_l


title: Female Liver, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p12_10109_r75_l


title: Female Liver, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p12_10109_r91_l

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Liver, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p12_10109_r65_l

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Liver, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p12_10109_r66_l

value: 8-10 weeks

value: No Issue


title: Female Liver, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p12_10109_r68_l


title: Female Liver, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p12_10109_r63_l


title: Female Liver, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p12_10109_r64_l


title: Female Liver, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p12_10109_r60_l

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Liver, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p12_10109_r61_l


title: Female Liver, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p12_10109_r62_l


title: Female Liver, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p12_10109_r57_l


title: Female Liver, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p12_10109_r59_l


title: Female Liver, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p12_10109_r58_l


title: Female Liver, Vehicle Control, Animal r53

description: Library name: p12_10109_r53_l

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Liver, Vehicle Control, Animal r51

description: Library name: p12_10109_r51_l

value: Female

value: Liver

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Liver, Vehicle Control, Animal r49

description: Library name: p12_10109_r49_l

value: Sprague Dawley

value: route of_exposure:Oral gavage


title: Female Liver, Vehicle Control, Animal r54

description: Library name: p12_10109_r54_l


title: Male Liver, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p11_10109_r48_l

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Liver, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p11_10109_r44_l

value: 8-10 weeks


title: Male Liver, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p11_10109_r43_l

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: No Issue


title: Male Liver, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p11_10109_r38_l

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Liver, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p11_10109_r47_l


title: Male Liver, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p11_10109_r40_l


title: Male Liver, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p11_10109_r39_l


title: Male Liver, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p11_10109_r41_l


title: Male Liver, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p11_10109_r34_l


title: Male Liver, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p11_10109_r37_l


title: Male Liver, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p11_10109_r35_l


title: Male Liver, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p11_10109_r33_l

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Liver, 16.7 mg/kg/day 73FTOH, Animal r30

description: Library name: p11_10109_r30_l

value: Liver

value: Sprague Dawley

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Liver, 16.7 mg/kg/day 73FTOH, Animal r31

description: Library name: p11_10109_r31_l

value: Male

value: route of_exposure:Oral gavage


title: Male Liver, 16.7 mg/kg/day 73FTOH, Animal r29

description: Library name: p11_10109_r29_l


title: Male Liver, 5 mg/kg/day 73FTOH, Animal r28

description: Library name: p11_10109_r28_l

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Liver, Vehicle Control, Animal r56

description: Library name: p12_10109_r56_l

value: Female

value: 8-10 weeks

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Liver, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p11_10109_r32_l

value: No Issue


title: Male Liver, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p11_10109_r42_l

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Liver, 5 mg/kg/day 73FTOH, Animal r26

description: Library name: p11_10109_r26_l

value: Liver


title: Male Liver, 5 mg/kg/day 73FTOH, Animal r27

description: Library name: p11_10109_r27_l

value: Sprague Dawley


title: Female Liver, Vehicle Control, Animal r50

description: Library name: p12_10109_r50_l

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Liver, Vehicle Control, Animal r52

description: Library name: p12_10109_r52_l


title: Male Liver, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p11_10109_r46_l

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Liver, 5 mg/kg/day 73FTOH, Animal r25

description: Library name: p11_10109_r25_l

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4

value: route of_exposure:Oral gavage


title: Male Liver, 1.7 mg/kg/day 73FTOH, Animal r23

description: Library name: p11_10109_r23_l

value: 8-10 weeks

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Male Liver, 1.7 mg/kg/day 73FTOH, Animal r22

description: Library name: p11_10109_r22_l

value: No Issue


title: Male Liver, 1.7 mg/kg/day 73FTOH, Animal r21

description: Library name: p11_10109_r21_l


title: Male Liver, 1.7 mg/kg/day 73FTOH, Animal r20

description: Library name: p11_10109_r20_l


title: Male Liver, 1.7 mg/kg/day 73FTOH, Animal r19

description: Library name: p11_10109_r19_l


title: Male Liver, 5 mg/kg/day 73FTOH, Animal r24

description: Library name: p11_10109_r24_l


title: Male Liver, 0.5 mg/kg/day 73FTOH, Animal r15

description: Library name: p11_10109_r15_l

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Liver, 0.5 mg/kg/day 73FTOH, Animal r18

description: Library name: p11_10109_r18_l

value: Liver

value: Sprague Dawley

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Liver, 0.5 mg/kg/day 73FTOH, Animal r17

description: Library name: p11_10109_r17_l

value: Male


title: Male Liver, 0.5 mg/kg/day 73FTOH, Animal r14

description: Library name: p11_10109_r14_l


title: Female Liver, Vehicle Control, Animal r55

description: Library name: p12_10109_r55_l

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Liver, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p11_10109_r36_l

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6

value: route of_exposure:Oral gavage


title: Male Liver, 0.05 mg/kg/day 73FTOH, Animal r13

description: Library name: p11_10109_r13_l

value: 8-10 weeks

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Male Liver, 0.5 mg/kg/day 73FTOH, Animal r16

description: Library name: p11_10109_r16_l

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2

value: No Issue


title: Male Liver, 0.05 mg/kg/day 73FTOH, Animal r12

description: Library name: p11_10109_r12_l

value: Male

value: Liver

value: Sprague Dawley

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Liver, 0.05 mg/kg/day 73FTOH, Animal r10

description: Library name: p11_10109_r10_l


title: Male Liver, Vehicle Control, Animal r05

description: Library name: p11_10109_r05_l

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Liver, Vehicle Control, Animal r06

description: Library name: p11_10109_r06_l


title: Male Liver, Vehicle Control, Animal r07

description: Library name: p11_10109_r07_l


title: Male Liver, Vehicle Control, Animal r08

description: Library name: p11_10109_r08_l


title: Male Liver, Vehicle Control, Animal r01

description: Library name: p11_10109_r01_l


title: Female Kidney, 500 mg/kg/day 73FTOH, Animal r96

description: Library name: p10_10109_r96_k

source_name: Kidney

value: Female

value: Kidney

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Liver, Vehicle Control, Animal r02

description: Library name: p11_10109_r02_l

value: 8-10 weeks

value: route of_exposure:Oral gavage


title: Male Liver, Vehicle Control, Animal r04

description: Library name: p11_10109_r04_l


title: Female Kidney, 500 mg/kg/day 73FTOH, Animal r95

description: Library name: p10_10109_r95_k


title: Female Kidney, 500 mg/kg/day 73FTOH, Animal r94

description: Library name: p10_10109_r94_k


title: Female Kidney, 500 mg/kg/day 73FTOH, Animal r93

description: Library name: p10_10109_r93_k


title: Female Kidney, 500 mg/kg/day 73FTOH, Animal r92

description: Library name: p10_10109_r92_k


title: Female Kidney, 167 mg/kg/day 73FTOH, Animal r91

description: Library name: p10_10109_r91_k

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Female Kidney, 167 mg/kg/day 73FTOH, Animal r90

description: Library name: p10_10109_r90_k

value: No Issue


title: Female Kidney, 167 mg/kg/day 73FTOH, Animal r89

description: Library name: p10_10109_r89_k


title: Female Kidney, 167 mg/kg/day 73FTOH, Animal r88

description: Library name: p10_10109_r88_k


title: Female Kidney, 50 mg/kg/day 73FTOH, Animal r85

description: Library name: p10_10109_r85_k

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Liver, 0.05 mg/kg/day 73FTOH, Animal r09

description: Library name: p11_10109_r09_l

value: Male

value: Liver

value: Sprague Dawley

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Kidney, 50 mg/kg/day 73FTOH, Animal r82

description: Library name: p10_10109_r82_k

value: Female

value: Kidney


title: Female Kidney, 50 mg/kg/day 73FTOH, Animal r84

description: Library name: p10_10109_r84_k

value: 8-10 weeks

value: route of_exposure:Oral gavage


title: Female Kidney, 50 mg/kg/day 73FTOH, Animal r86

description: Library name: p10_10109_r86_k


title: Female Kidney, 50 mg/kg/day 73FTOH, Animal r83

description: Library name: p10_10109_r83_k


title: Female Kidney, 16.7 mg/kg/day 73FTOH, Animal r80

description: Library name: p10_10109_r80_k

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Female Kidney, 167 mg/kg/day 73FTOH, Animal r87

description: Library name: p10_10109_r87_k

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7

value: No Issue


title: Male Liver, 0.05 mg/kg/day 73FTOH, Animal r11

description: Library name: p11_10109_r11_l

value: Male

value: Liver


title: Male Liver, Vehicle Control, Animal r03

description: Library name: p11_10109_r03_l

value: Sprague Dawley

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Kidney, 16.7 mg/kg/day 73FTOH, Animal r81

description: Library name: p10_10109_r81_k

value: Female

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Kidney, 16.7 mg/kg/day 73FTOH, Animal r78

description: Library name: p10_10109_r78_k

value: Kidney

value: 8-10 weeks


title: Female Kidney, 16.7 mg/kg/day 73FTOH, Animal r79

description: Library name: p10_10109_r79_k

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: route of_exposure:Oral gavage


title: Female Kidney, 5 mg/kg/day 73FTOH, Animal r76

description: Library name: p10_10109_r76_k

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Kidney, 5 mg/kg/day 73FTOH, Animal r74

description: Library name: p10_10109_r74_k


title: Female Kidney, 5 mg/kg/day 73FTOH, Animal r73

description: Library name: p10_10109_r73_k


title: Female Kidney, 1.7 mg/kg/day 73FTOH, Animal r69

description: Library name: p10_10109_r69_k

value: 1.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:1.7 mg/kg/day

value: dose group:3


title: Female Kidney, 16.7 mg/kg/day 73FTOH, Animal r77

description: Library name: p10_10109_r77_k

value: dose:16.7 mg/kg/day

value: dose group:5

value: No Issue


title: Female Kidney, 1.7 mg/kg/day 73FTOH, Animal r71

description: Library name: p10_10109_r71_k

value: Sprague Dawley


title: Female Kidney, 5 mg/kg/day 73FTOH, Animal r72

description: Library name: p10_10109_r72_k


title: Female Kidney, 1.7 mg/kg/day 73FTOH, Animal r70

description: Library name: p10_10109_r70_k


title: Female Kidney, 1.7 mg/kg/day 73FTOH, Animal r68

description: Library name: p10_10109_r68_k


title: Female Kidney, 1.7 mg/kg/day 73FTOH, Animal r67

description: Library name: p10_10109_r67_k


title: Female Kidney, 0.5 mg/kg/day 73FTOH, Animal r65

description: Library name: p10_10109_r65_k

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Female Kidney, 0.5 mg/kg/day 73FTOH, Animal r63

description: Library name: p10_10109_r63_k

value: Female

value: Kidney

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Female Kidney, 0.5 mg/kg/day 73FTOH, Animal r62

description: Library name: p10_10109_r62_k

value: 8-10 weeks

value: route of_exposure:Oral gavage


title: Female Kidney, 0.5 mg/kg/day 73FTOH, Animal r64

description: Library name: p10_10109_r64_k


title: Female Kidney, 0.05 mg/kg/day 73FTOH, Animal r61

description: Library name: p10_10109_r61_k

value: 0.05 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.05 mg/kg/day

value: dose group:1


title: Female Kidney, 0.05 mg/kg/day 73FTOH, Animal r59

description: Library name: p10_10109_r59_k


title: Female Kidney, 0.05 mg/kg/day 73FTOH, Animal r60

description: Library name: p10_10109_r60_k


title: Female Kidney, 0.05 mg/kg/day 73FTOH, Animal r58

description: Library name: p10_10109_r58_k


title: Female Kidney, 0.05 mg/kg/day 73FTOH, Animal r57

description: Library name: p10_10109_r57_k


title: Female Kidney, Vehicle Control, Animal r53

description: Library name: p10_10109_r53_k

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Female Kidney, 5 mg/kg/day 73FTOH, Animal r75

description: Library name: p10_10109_r75_k

value: 5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:5 mg/kg/day

value: dose group:4


title: Female Kidney, Vehicle Control, Animal r52

description: Library name: p10_10109_r52_k

value: Sprague Dawley

value: No Issue


title: Female Kidney, Vehicle Control, Animal r54

description: Library name: p10_10109_r54_k


title: Female Kidney, Vehicle Control, Animal r51

description: Library name: p10_10109_r51_k


title: Female Kidney, Vehicle Control, Animal r56

description: Library name: p10_10109_r56_k


title: Male Kidney, 500 mg/kg/day 73FTOH, Animal r48

description: Library name: p09_10109_r48_k

value: Male

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Female Kidney, Vehicle Control, Animal r50

description: Library name: p10_10109_r50_k

value: Female

value: Kidney

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)


title: Male Kidney, 500 mg/kg/day 73FTOH, Animal r46

description: Library name: p09_10109_r46_k

value: route of_exposure:Oral gavage


title: Female Kidney, Vehicle Control, Animal r49

description: Library name: p10_10109_r49_k

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage


title: Female Kidney, 0.5 mg/kg/day 73FTOH, Animal r66

description: Library name: p10_10109_r66_k

value: 0.5 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:0.5 mg/kg/day

value: dose group:2


title: Male Kidney, 500 mg/kg/day 73FTOH, Animal r47

description: Library name: p09_10109_r47_k


title: Male Kidney, 167 mg/kg/day 73FTOH, Animal r41

description: Library name: p09_10109_r41_k

value: 167 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:167 mg/kg/day

value: dose group:7


title: Male Kidney, 167 mg/kg/day 73FTOH, Animal r43

description: Library name: p09_10109_r43_k

value: Sprague Dawley

value: No Issue


title: Male Kidney, 167 mg/kg/day 73FTOH, Animal r39

description: Library name: p09_10109_r39_k

value: Male


title: Male Kidney, 167 mg/kg/day 73FTOH, Animal r42

description: Library name: p09_10109_r42_k


title: Male Kidney, 50 mg/kg/day 73FTOH, Animal r38

description: Library name: p09_10109_r38_k

value: 50 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:50 mg/kg/day

value: dose group:6


title: Male Kidney, 500 mg/kg/day 73FTOH, Animal r44

description: Library name: p09_10109_r44_k

value: Kidney

value: 500 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:500 mg/kg/day

value: dose group:8


title: Male Kidney, 167 mg/kg/day 73FTOH, Animal r40

description: Library name: p09_10109_r40_k

value: 8-10 weeks

value: chemical name:7:3 Fluorotelomer alcohol (7:3 FTOH)

value: route of_exposure:Oral gavage


title: Male Kidney, 50 mg/kg/day 73FTOH, Animal r37

description: Library name: p09_10109_r37_k


title: Male Kidney, 50 mg/kg/day 73FTOH, Animal r36

description: Library name: p09_10109_r36_k


title: Male Kidney, 50 mg/kg/day 73FTOH, Animal r34

description: Library name: p09_10109_r34_k


title: Male Kidney, 16.7 mg/kg/day 73FTOH, Animal r33

description: Library name: p09_10109_r33_k

value: 16.7 mg/kg/day 73FTOH, 5-day repeat exposure, oral gavage

value: dose:16.7 mg/kg/day

value: dose group:5


title: Male Kidney, 50 mg/kg/day 73FTOH, Animal r35

description: Library name: p09_10109_r35_k


title: Female Kidney, Vehicle Control, Animal r55

description: Library name: p10_10109_r55_k

value: Female

value: 1,2-Propylene glycol control, 5-day repeat exposure, oral gavage

value: dose:0 mg/kg/day

value: dose group:0


title: Male Kidney, 16.7 mg/kg/day 73FTOH, Animal r32

description: Library name: p09_10109_r32_k

value: Male

value: Sprague Dawley

value: No Issue