title: HEK293T_IscB_omegaRNA_ALDH1A3_Og1.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og1.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og1.rep2

status: Public on Jan 19 2026

type: SRA

city: Hohhot

first: Lei

last: Yang

state: Inner Mongolia Autonomous Region

address: 24 Zhaojun Rd.

department: State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock

country: China

institute: Inner Mongolia University

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og1.rep2

library_source: genomic

data_processing:
Data analysis was performed using CRISPResso2. The editing efficiencies were quantified as the percentage of total sequencing reads containing indels.
Assembly: GRCh38
Supplementary files format and content: the average and SD values of the running results of CRISPResso, which are grouped statistics based on the running results of CRISPResso

molecule: genomic DNA

organism: Homo sapiens

source_name: Kidney

extract_protocol:
the genomic DNA was extracted from transfected cells, infected embryos, and cattle ear-tips using the TIANamp Genomic DNA Kit (Tiangen) or QIAamp DNA Mini Kit (Qiagen) according to the manufacturer’s instructions.
Genomic sites of interest were amplified using unique barcoding primer pairs with Phanta Max Super-Fidelity DNA Polymerase (Vazyme) for deep sequencing. The PCR products were pooled by common amplicons and sequenced with pair-end 150 bp on the HiSeq 4000 system (Illumina).

tag: tissue

value: Kidney

tag: cell line

tag: cell type

value: Human embryonic kidney cells

tag: treatment


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og5.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og5.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og2.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og2.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og4.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og4.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og17.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og17.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og18.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og18.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og17.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og17.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og17.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og17.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og16.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og16.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og15.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og15.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og20.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og20.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og19.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og19.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og2.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og2.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og1.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og1.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og19.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og19.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og14.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og14.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og18.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og18.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og14.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og14.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og15.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og15.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og15.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og15.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og19.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og19.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og14.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og14.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og16.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og16.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og13.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og13.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og12.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og12.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og11.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og11.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og16.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og16.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og13.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og13.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og12.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og12.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og13.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og13.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og12.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og12.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og11.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og11.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og10.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og10.rep3


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og10.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og10.rep2


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og10.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og10.rep1


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og8.rep3

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og8.rep3


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg6.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg6.rep3
Target.HeLa.editing_frequency.txt

data_processing:
Data analysis was performed using CRISPResso2. The editing efficiencies were quantified as the percentage of total sequencing reads containing indels.
Assembly: GRCh38,MM39
Supplementary files format and content: the average and SD values of the running results of CRISPResso, which are grouped statistics based on the running results of CRISPResso

source_name: Cervical carcinoma

value: Cervical carcinoma

value: HeLa

value: Human cervical carcinom cells

tag: sample group


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg6.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg6.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg5.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg6.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg6.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg5.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og11.rep1

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og11.rep1


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg5.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg3.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg2.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg4.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg3.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg2.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg2.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg1.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg4.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg2.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg1.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg3.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg3.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg1.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg3.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg1.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg2.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_ALDH1A3_Og18.rep2

description: Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Og18.rep2


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg1.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg6.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg6.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg6.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg6.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg4.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg5.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg3.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg4.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg5.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg4.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_VEGFA_Tg1.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_VEGFA_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg1.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg2.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg1.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_PCSK9_Tg2.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_PCSK9_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg3.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg2.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg1.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg3.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg2.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg6.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg6.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg2.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg5.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg5.rep1
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg2.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg1.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg3.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg4.rep1

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg1.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg1.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_CXCR4_Tg1.rep2

description:
Library name: HeLa_proIscB_proomegaRNA_CXCR4_Tg1.rep2
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg3.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg4.rep1
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg4.rep2
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg5.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg3.rep1
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_proIscB_proomegaRNA_EMX1_Tg2.rep3

description:
Library name: HeLa_proIscB_proomegaRNA_EMX1_Tg2.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg2.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg2.rep2
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg1.rep2
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg2.rep1
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg1.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg6.rep3

description:
Library name: HeLa_NTC_VEGFA_Tg6.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HeLa_proIscB_proomegaRNA_ALDH1A3_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg6.rep2

description:
Library name: HeLa_NTC_VEGFA_Tg6.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg3.rep3

description:
Library name: HeLa_NTC_VEGFA_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg4.rep1

description:
Library name: HeLa_NTC_VEGFA_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg5.rep2

description:
Library name: HeLa_NTC_VEGFA_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg4.rep3

description:
Library name: HeLa_NTC_VEGFA_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg2.rep3

description:
Library name: HeLa_NTC_VEGFA_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg2.rep2

description:
Library name: HeLa_NTC_VEGFA_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg2.rep1

description:
Library name: HeLa_NTC_VEGFA_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg3.rep2

description:
Library name: HeLa_NTC_VEGFA_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg3.rep3

description:
Library name: HeLa_NTC_PCSK9_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg2.rep3

description:
Library name: HeLa_NTC_PCSK9_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg6.rep1

description:
Library name: HeLa_NTC_VEGFA_Tg6.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg2.rep1

description:
Library name: HeLa_NTC_PCSK9_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg5.rep1

description:
Library name: HeLa_NTC_VEGFA_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg1.rep1

description:
Library name: HeLa_NTC_VEGFA_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg4.rep2

description:
Library name: HeLa_NTC_VEGFA_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg1.rep1

description:
Library name: HeLa_NTC_PCSK9_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg3.rep1

description:
Library name: HeLa_NTC_PCSK9_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg3.rep1

description:
Library name: HeLa_NTC_VEGFA_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg1.rep2

description:
Library name: HeLa_NTC_VEGFA_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg1.rep3

description:
Library name: HeLa_NTC_VEGFA_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg3.rep2

description:
Library name: HeLa_NTC_PCSK9_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg1.rep3

description:
Library name: HeLa_NTC_PCSK9_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg6.rep2

description:
Library name: HeLa_NTC_EMX1_Tg6.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg6.rep3

description:
Library name: HeLa_NTC_EMX1_Tg6.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg2.rep2

description:
Library name: HeLa_NTC_PCSK9_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg6.rep1

description:
Library name: HeLa_NTC_EMX1_Tg6.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg2.rep3

description:
Library name: HeLa_NTC_EMX1_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg4.rep2

description:
Library name: HeLa_NTC_EMX1_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg5.rep2

description:
Library name: HeLa_NTC_EMX1_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg5.rep1

description:
Library name: HeLa_NTC_EMX1_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg2.rep2

description:
Library name: HeLa_NTC_EMX1_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg4.rep3

description:
Library name: HeLa_NTC_EMX1_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg5.rep3

description:
Library name: HeLa_NTC_EMX1_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_VEGFA_Tg5.rep3

description:
Library name: HeLa_NTC_VEGFA_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_PCSK9_Tg1.rep2

description:
Library name: HeLa_NTC_PCSK9_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg2.rep3

description:
Library name: HeLa_NTC_CXCR4_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg1.rep1

description:
Library name: HeLa_NTC_EMX1_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg3.rep3

description:
Library name: HeLa_NTC_CXCR4_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg1.rep3

description:
Library name: HeLa_NTC_EMX1_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg1.rep2

description:
Library name: HeLa_NTC_EMX1_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg2.rep1

description:
Library name: HeLa_NTC_EMX1_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg2.rep2

description:
Library name: HeLa_NTC_CXCR4_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg3.rep2

description:
Library name: HeLa_NTC_CXCR4_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg1.rep1

description:
Library name: HeLa_NTC_CXCR4_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg4.rep2

description:
Library name: HeLa_NTC_ALDH1A3_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_EMX1_Tg4.rep1

description:
Library name: HeLa_NTC_EMX1_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg5.rep1

description:
Library name: HeLa_NTC_ALDH1A3_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg3.rep1

description:
Library name: HeLa_NTC_CXCR4_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg5.rep3

description:
Library name: HeLa_NTC_ALDH1A3_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg4.rep1

description:
Library name: HeLa_NTC_ALDH1A3_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg4.rep3

description:
Library name: HeLa_NTC_ALDH1A3_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg1.rep3

description:
Library name: HeLa_NTC_CXCR4_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg1.rep2

description:
Library name: HeLa_NTC_CXCR4_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_CXCR4_Tg2.rep1

description:
Library name: HeLa_NTC_CXCR4_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg5.rep2

description:
Library name: HeLa_NTC_ALDH1A3_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg3.rep1

description:
Library name: HeLa_NTC_ALDH1A3_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg2.rep3

description:
Library name: HeLa_NTC_ALDH1A3_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg2.rep2

description:
Library name: HeLa_NTC_ALDH1A3_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg1.rep2

description:
Library name: HeLa_NTC_ALDH1A3_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg3.rep2

description:
Library name: HeLa_NTC_ALDH1A3_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg6.rep2

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg6.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg5.rep3

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg6.rep1

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg6.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg4.rep1

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg1.rep1

description:
Library name: HeLa_NTC_ALDH1A3_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg6.rep3

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg6.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg4.rep3

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg4.rep2

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg5.rep2

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg3.rep2

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg1.rep3

description:
Library name: HeLa_NTC_ALDH1A3_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg5.rep1

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg2.rep2

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg3.rep3

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg3.rep1

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg2.rep1

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg2.rep3

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg3.rep2

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg3.rep1

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg3.rep3

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg1.rep1

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg1.rep3

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_VEGFA_Tg1.rep2

description:
Library name: HeLa_IscB_omegaRNA_VEGFA_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_NTC_ALDH1A3_Tg3.rep3

description:
Library name: HeLa_NTC_ALDH1A3_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg4.rep2

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg1.rep2

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg6.rep3

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg6.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg1.rep2

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg1.rep1

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg6.rep1

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg6.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg1.rep3

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg5.rep3

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg5.rep1

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg5.rep2

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg4.rep3

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg2.rep3

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg2.rep3

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg2.rep3

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg6.rep2

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg6.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg4.rep1

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg1.rep1

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg2.rep2

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg2.rep1

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg2.rep2

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg5.rep3

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg5.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_PCSK9_Tg2.rep1

description:
Library name: HeLa_IscB_omegaRNA_PCSK9_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg2.rep2

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_EMX1_Tg1.rep3

description:
Library name: HeLa_IscB_omegaRNA_EMX1_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg3.rep1

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg4.rep2

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg4.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg3.rep3

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg1.rep3

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg1.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg2.rep1

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg1.rep2

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg4.rep1

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg4.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg3.rep3

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg3.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg2.rep1

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg1.rep1

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg1.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg2.rep2

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg2.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg3.rep2

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg4.rep3

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg4.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg5.rep2

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg5.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg1.rep2

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg1.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg5.rep1

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg5.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_CXCR4_Tg3.rep2

description:
Library name: HeLa_IscB_omegaRNA_CXCR4_Tg3.rep2
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg1.rep1

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg1.rep1
Target.HeLa.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg3.rep1

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg3.rep1
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg2.rep3

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg2.rep3
Target.HeLa.editing_frequency.txt


title: HeLa_IscB_omegaRNA_ALDH1A3_Tg1.rep3

description:
Library name: HeLa_IscB_omegaRNA_ALDH1A3_Tg1.rep3
Target.HeLa.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg4.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg6.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg4.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg6.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg6.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg2.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg1.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg3.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg5.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg2.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg2.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg4.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg1.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg1.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg5.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg3.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg3.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg3.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg2.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg1.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg3.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg3.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg6.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg6.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg1.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg4.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg4.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg4.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: pouch_SAM_biorep3

city: Wageningen

first: Merijn

last: Kerstens

address: Droevendaalsesteeg 1

department: Plant Developmental Biology

country: Netherlands

institute: Wageningen University & Research

description: Library name: csa_pouch_SAM_3

library_source: transcriptomic

data_processing:
Raw reads were trimmed with fastp v0.23.4
Counts were generated with kallisto v0.46.1
Assembly: Chinese Long '9930' V3
Supplementary files format and content: TSV format of estimated counts by kallisto

molecule: total RNA

organism: Cucumis sativus

source_name: shoot apical meristem

growth_protocol: Cucumber apices were dissected from 6 dpg seedlings grown on an agar plate filled with soil and covered by a nylon mesh (7 pooled apices per replicate) or in wet germination pouches (20 pooled apices per replicate). The seedlings were grown under long day conditions (16 h light, 8 h dark) at 22 degrees.

extract_protocol:
Tissue was collected in RNAlater on ice. Total RNA was extracted according to the LogSpin protocol (Yaffe et al, 2012) and purified with EtOH precipitation
The NEBNext Ultra II Directional RNA Library Prep Kit was used at GenomeScan BV according to the manufacturers instructions

value: shoot apical meristem

tag: genotype

tag: growth condition


description:
Library name: HEK293T_proIscB_proomegaRNA_VEGFA_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: pouch_SAM_biorep2

description: Library name: csa_pouch_SAM_2


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg2.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg6.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: soil_SAM_biorep2

description: Library name: csa_soil_SAM_2


description:
Library name: HEK293T_proIscB_proomegaRNA_PCSK9_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: pouch_SAM_biorep1

description: Library name: csa_pouch_SAM_1


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg5.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg1.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg2.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg1.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: soil_SAM_biorep1

description: Library name: csa_soil_SAM_1


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg2.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: soil_SAM_biorep3

description: Library name: csa_soil_SAM_3


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg3.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: 3xFLAG-CsPLT5_DAP_rep1

description: Library name: CsPLT5_DAP_SAM_1

data_processing:
Adapter trimming was performed with fastp v0.23.2, specifying --trim_poly_g.
Reads were mapped to the reference genome with BWA-MEM v0.7.17.
Unmapped, duplicate, and mapping quality < 30 reads were removed with SAMtools v1.15 and Sambamba v0.6.6.
Peaks were called separately for each sample (incl. GFP) with MACS3 v3.0.0a7 at a q-value = 0.1 cutoff.
Assembly: Chinese Long 9930 V3
Supplementary files format and content: Narrowpeaks files per sample with peak locations

growth_protocol: Seedlings were grown for six days in wet germination pouches (CYG) under long day (18 h light, 6 h dark) conditions in a greenhouse with fluctuating temperatures (day: 20.5 °C; night: 16 °C).

extract_protocol:
Per replicate, 100 shoot apical meristems were collected on ice, then ground with a metal ball in a TissueLyzer LT (Qiagen). CTAB DNA extraction was used on the remaining powder.
DAP-seq libraries were prepared according to Bartlett et al., (2017) with Illumina TruSeq barcodes. 100 ng of gDNA was used as starting material. Libraries were amplified using 15 cycles. Post-amplification libraries were size selected at >200 bp in length using AMPure XP beads.

value: Rijk Zwaan proprietary parental line

tag: dap protein

tag: replicate


title: 3xFLAG-CsPLT5_DAP_rep2

description: Library name: CsPLT5_DAP_SAM_2


title: HeLa_NTC_ALDH1A3_Tg2.rep1

description:
Library name: HeLa_NTC_ALDH1A3_Tg2.rep1
Target.HeLa.editing_frequency.txt


title: 3xFLAG-CsPLT3/7_DAP_rep2

description: Library name: CsPLT3/7_DAP_SAM_2


title: 3xFLAG-GFP_DAP_rep1

description: Library name: GFP_DAP_SAM_1


title: 3xFLAG-CsPLT3/7_DAP_rep1

description: Library name: CsPLT3/7_DAP_SAM_1


description:
Library name: HEK293T_proIscB_proomegaRNA_EMX1_Tg1.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg2.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: 3xFLAG-GFP_DAP_rep2

description: Library name: GFP_DAP_SAM_2


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg5.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg1.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg1.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: HT8MFP

city: Madison

first: Jimena

last: Laporta

state: Wisconsin

address: 1675 Observatory Dr Madison

department: Department of Dairy Science

country: USA

institute: University of Wisconsin Madison

description:
Library name: Sample 16
Column name in raw_counts_All samples.txt: HT8MFP

data_processing:
A standardized bioinformatics pipeline on the High-Performance Computing Cluster (HPCC) at Michigan State University
Raw paired-end FASTQ files were first assessed for base quality, duplication levels, and adapter contamination using FastQC v0.11.9.
Reads were trimmed using Trimmomatic v0.40, which wraps Cutadapt with parameters set to remove low-quality bases (Phred score < 20) and adapter sequences.
Assembly: Trimmed reads were aligned with refference genome (Bos taurus ARS-UCD1.2) using STAR v2.7.10a
Supplementary files format and content: A transcript FASTA was generated from the genome and GTF using gffread prior to indexing. Transcript level estimates (TPM and counts) were imported into R with tximport and summarized to genes using effective length–aware aggregation
Supplementary files format and content: Differential expression of genes was performed in R v4.3.1 using DESeq2 v1.38.3

organism: Bos taurus

source_name: Mammary fat pad

extract_protocol:
RNA was extracted using Qiagen RNeasy Plus Universal Mini Kit (Qiagen; #73404) following the manufacturer’s instructions for sequencing
RNA libraries were constructed using the NEBNext Ultra II RNA Library Prep Kit for Illumina (#E7775; New England BioLabs) following the manufacturer’s protocol.

value: Mammary fat pad


title: HT6MFP

description:
Library name: Sample 14
Column name in raw_counts_All samples.txt: HT6MFP


title: HT4MFP

description:
Library name: Sample 12
Column name in raw_counts_All samples.txt: HT4MFP


description:
Library name: HEK293T_proIscB_proomegaRNA_CXCR4_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: HT2MFP

description:
Library name: Sample 10
Column name in raw_counts_All samples.txt: HT2MFP


title: HT7MFP

description:
Library name: Sample 15
Column name in raw_counts_All samples.txt: HT7MFP


title: HT3MFP

description:
Library name: Sample 11
Column name in raw_counts_All samples.txt: HT3MFP


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg4.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: HT5MFP

description:
Library name: Sample 13
Column name in raw_counts_All samples.txt: HT5MFP


title: HT1MFP

description:
Library name: Sample 9
Column name in raw_counts_All samples.txt: HT1MFP


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: CL5MFP

description:
Library name: Sample 5
Column name in raw_counts_All samples.txt: CL5MFP


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg4.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: CL3MFP

description:
Library name: Sample 3
Column name in raw_counts_All samples.txt: CL3MFP


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg2.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_VEGFA_Tg6.rep3

description:
Library name: HEK293T_NTC_VEGFA_Tg6.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: CL8MFP

description:
Library name: Sample 8
Column name in raw_counts_All samples.txt: CL8MFP


title: CL4MFP

description:
Library name: Sample 4
Column name in raw_counts_All samples.txt: CL4MFP


title: CL7MFP

description:
Library name: Sample 7
Column name in raw_counts_All samples.txt: CL7MFP


title: HEK293T_NTC_VEGFA_Tg6.rep2

description:
Library name: HEK293T_NTC_VEGFA_Tg6.rep2
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-15a, mock, Day0, biol rep 1

city: Beijing

first: Chao

last: Xiang

address: No. 2 Yuanmingyuan West Road, Haidian District

institute: Institute of plant protection, Chinese academy of agriculture sciences

description: Library name: Sample 6 biol rep 1

data_processing:
To obtain high quality clean reads, raw reads were further filtered by Cutadapt (https://cutadapt.readthedocs.io/en/stable/, version: cutadapt-1.9). Reads of all samples were mapped to the soybean reference genome (Wm82.a4.v1, released from the https://www.soybase.org) using HISAT2 (https://daehwankimlab.github.io/hisat2/, version:hisat2-2.2.1) package. StringTie and ballgown (http://www.bioconductor.org/packages/release/bioc/html/ballgown.html) were used to estimate the expression levels of all the transcripts and to perform expression abundance for mRNAs by calculating fragment per kilobase of transcript per million mapped reads (FPKM) value
Assembly: Wm82.a4.v1
Supplementary files format and content: tab-delimited text file includes raw counts for each Sample

organism: Glycine max

source_name: hairy roots

extract_protocol:
Total RNA was extracted using Trizol reagent (thermofisher, 15596018). RNA quantity and purity were analyzed using Bioanalyzer 2100 and RNA 6000 Nano LabChip Kit (Agilent, CA, USA, 5067-1511)
Library construction for mRNA sequencing was conducted using the SuperScriptTM II Reverse Transcriptase (Invitrogen, cat. 1896649, USA) following the manufacturer’s recommendations

value: hairy roots

value: hairy root cells

value: Over-expression

value: mock


title: Over-expression GmHSP70-15a, inoculated soybean cyst nematode, Day3, biol rep 1

description: Library name: Sample 7 biol rep 1

value: inoculated soybean cyst nematode


title: Over-expression GmHSP70-15a, inoculated soybean cyst nematode, Day3, biol rep 3

description: Library name: Sample 7 biol rep 3


title: Over-expression GmHSP70-15a, mock, Day0, biol rep 3

description: Library name: Sample 6 biol rep 3


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg2.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-15a, inoculated soybean cyst nematode, Day3, biol rep 2

description: Library name: Sample 7 biol rep 2


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: CL6MFP

description:
Library name: Sample 6
Column name in raw_counts_All samples.txt: CL6MFP


title: HEK293T_NTC_VEGFA_Tg5.rep2

description:
Library name: HEK293T_NTC_VEGFA_Tg5.rep2
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg1.rep3
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-13a, inoculated soybean cyst nematode, Day3, biol rep 2

description: Library name: Sample 5 biol rep 2


title: CL1MFP

description:
Library name: sample 1
Column name in raw_counts_All samples.txt: CL1MFP


title: HEK293T_NTC_VEGFA_Tg6.rep1

description:
Library name: HEK293T_NTC_VEGFA_Tg6.rep1
Target.HEK293T.editing_frequency.txt


description:
Library name: HEK293T_proIscB_proomegaRNA_ALDH1A3_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-13a, inoculated soybean cyst nematode, Day3, biol rep 1

description: Library name: Sample 5 biol rep 1


title: HEK293T_NTC_VEGFA_Tg5.rep1

description:
Library name: HEK293T_NTC_VEGFA_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-15a, mock, Day0, biol rep 2

description: Library name: Sample 6 biol rep 2


title: Over-expression GmHSP70-13a, mock, Day0, biol rep 3

description: Library name: Sample 4 biol rep 3


title: HEK293T_NTC_VEGFA_Tg4.rep2

description:
Library name: HEK293T_NTC_VEGFA_Tg4.rep2
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-13a, inoculated soybean cyst nematode, Day3, biol rep 3

description: Library name: Sample 5 biol rep 3


title: HEK293T_NTC_VEGFA_Tg4.rep1

description:
Library name: HEK293T_NTC_VEGFA_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: CL2MFP

description:
Library name: sample 2
Column name in raw_counts_All samples.txt: CL2MFP


title: HEK293T_NTC_VEGFA_Tg3.rep3

description:
Library name: HEK293T_NTC_VEGFA_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: Over-expression empty vector, inoculated soybean cyst nematode, Day3, biol rep 3

description: Library name: Sample 3 biol rep 3


title: HEK293T_NTC_VEGFA_Tg3.rep2

description:
Library name: HEK293T_NTC_VEGFA_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_VEGFA_Tg2.rep2

description:
Library name: HEK293T_NTC_VEGFA_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: Over-expression GmHSP70-13a, mock, Day0, biol rep 2

description: Library name: Sample 4 biol rep 2


title: Over-expression empty vector, inoculated soybean cyst nematode, Day3, biol rep 1

description: Library name: Sample 3 biol rep 1


title: Over-expression empty vector, inoculated soybean cyst nematode, Day3, biol rep 2

description: Library name: Sample 3 biol rep 2


title: Over-expression GmHSP70-13a, mock, Day0, biol rep 1

description: Library name: Sample 4 biol rep 1


title: HEK293T_NTC_VEGFA_Tg3.rep1

description:
Library name: HEK293T_NTC_VEGFA_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_VEGFA_Tg1.rep3

description:
Library name: HEK293T_NTC_VEGFA_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: WT, mock, Day0, biol rep 2

description: Library name: Sample 1 biol rep 2

value: WT


title: HEK293T_NTC_VEGFA_Tg1.rep1

description:
Library name: HEK293T_NTC_VEGFA_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: Over-expression empty vector, mock, Day0, biol rep 2

description: Library name: Sample 2 biol rep 2


title: HEK293T_NTC_VEGFA_Tg2.rep3

description:
Library name: HEK293T_NTC_VEGFA_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_VEGFA_Tg5.rep3

description:
Library name: HEK293T_NTC_VEGFA_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_VEGFA_Tg1.rep2

description:
Library name: HEK293T_NTC_VEGFA_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_VEGFA_Tg4.rep3

description:
Library name: HEK293T_NTC_VEGFA_Tg4.rep3
Target.HEK293T.editing_frequency.txt


title: Over-expression empty vector, mock, Day0, biol rep 1

description: Library name: Sample 2 biol rep 1


title: RNA-seq, leaf, Koshihikari, green manure, Year 2024, rep2

city: Tsukuba

first: Hirofunmi

last: Fukuda

state: Ibaraki

address: 1-31-1 Kannondai

country: Japan

institute: National Agriculture and Food Research Organization (NARO)

description:
Library name: rna_Koshi_GM_2024_rep2
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2024: 2024_GM_rep2

data_processing:
The libraries were sequenced using the Illumina NovaSeq X Plus. Sequencing was performed on the 25B flow cell with paired-end 150-bp and unique dual-index reads. The reads were preprocessed by CLC Genomics Workbench version 25.0 (Qiagen). Reads were first trimmed using the following parameters: quality limit of 0.05, maximum number of ambiguities 2. Next, raw reads were mapped to the genome assembly and gene sets of Os-Nipponbare-IRGSP-1.0 with the following parameters: mismatch cost of 2, insertion–deletion cost of 3, length fraction of 0.8, similarity fraction of 0.8, and maximum number of hits of a read of 10. Then, uniquely mapped read counts were quantified. Genes with at least one raw read count in all of the library samples for each comparison were analyzed.
Assembly: Os-Nipponbare-IRGSP-1.0
Supplementary files format and content: csv file includes RNA-seq raw count on whole transcripts for each sample.

molecule: polyA RNA

organism: Oryza sativa

source_name: leaf

growth_protocol: Seeds of rice cultivar ‘Koshihikari’ were soaked in water at 30 °C for 2 d, sown in trays filled with synthetic granular soil (Sumitomo Chemical Company Co., Ltd., Japan), and incubated at 30 °C in the dark for 2 d. The seeds were sown on April 17 or 24, 2023, and on April 5 or 22, 2024. those trays placed in a field (fertilization with 19:19:19 kg/ha for N:PO4:K) for nearly 3 weeks to 1 month and then transplanted by hand or with a rice planter (18 cm apart × 30 cm apart, planting density 18.5 hills/m2) into the desired field conditions. A normal paddy field condition (fertilization with 56:176:56:90:120 kg/ha of N:PO4:K:Mg:SiO2) was set as the control condition. No chemical fertilizers were added to the green manure–treated soil. For green manure treatment, Hairy vetch (Vicia villosa), a legume species, was grown as a cover crop in a paddy field. The seeds (30 kg/ha; Fujiemon [Massa], Snow Brand Seed Co., Ltd.) were sown in field by hand on October 21, 2022, for rice cultivation in 2023. For rice cultivation in 2024, we sowed that same amount of hairy vetch seeds on October 31 and again on November 15, 2023 (i.e., 60 kg/ha in total) since the firstly sowed seeds were little grown. The hairy vetch plants were grown for 5 months from October to April in 2023 and 2024, and then directly plowed into the soil.

extract_protocol:
The largest leaf of vegetative ‘Koshihikari’ plants sampled at 47 DAT (2023) and 38 DAT (2024) was collected. Each leaf (one biological replicate) was collected between 09:00 and 10:00, immediately frozen in liquid nitrogen and stocked until sample crushing. Frozen samples were crushed by a multi-specimen cell disruption device (BMS-A20TP; BMS) just before RNA extraction. Total RNA from each sample was extracted using an RNeasy Plant Mini Kit (Qiagen) according to the manufacturer’s protocol. Three to four biological replicates were obtained for each cultivation condition.
RNA-sequencing (RNA-seq) libraries were prepared using the NEBNext Ultra II Directional mRNA-seq kit for Illumina (New England Biolabs), following the manufacturer’s protocols.

treatment_protocol: Chemical fertilizer was applied as a basal dressing at 56:176:56:90:120 kg/ha (N:PO4:K:Mg:SiO2). Green-manure treatment consisted of hairy vetch–derived nutrients with no additional chemical fertilizer.

value: leaf

value: GM


title: WT, mock, Day0, biol rep 1

description: Library name: Sample 1 biol rep 1


title: HEK293T_NTC_PCSK9_Tg3.rep2

description:
Library name: HEK293T_NTC_PCSK9_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_PCSK9_Tg2.rep2

description:
Library name: HEK293T_NTC_PCSK9_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_PCSK9_Tg3.rep3

description:
Library name: HEK293T_NTC_PCSK9_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_PCSK9_Tg2.rep3

description:
Library name: HEK293T_NTC_PCSK9_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2024, rep2

description:
Library name: rna_Koshi_CF_2024_rep2
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2024: 2024_CF_rep2

value: CF


title: Over-expression empty vector, mock, Day0, biol rep 3

description: Library name: Sample 2 biol rep 3


title: HEK293T_NTC_PCSK9_Tg2.rep1

description:
Library name: HEK293T_NTC_PCSK9_Tg2.rep1
Target.HEK293T.editing_frequency.txt

value: Kidney


title: RNA-seq, leaf, Koshihikari, green manure, Year 2023, rep3

description:
Library name: rna_Koshi_GM_2023_rep3
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_GM_rep3


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2024, rep3

description:
Library name: rna_Koshi_CF_2024_rep3
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2024: 2024_CF_rep3


title: WT, mock, Day0, biol rep 3

description: Library name: Sample 1 biol rep 3


title: HEK293T_NTC_PCSK9_Tg1.rep1

description:
Library name: HEK293T_NTC_PCSK9_Tg1.rep1
Target.HEK293T.editing_frequency.txt

value: Human embryonic kidney cells


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2024, rep1

description:
Library name: rna_Koshi_CF_2024_rep1
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2024: 2024_CF_rep1


title: RNA-seq, leaf, Koshihikari, green manure, Year 2023, rep2

description:
Library name: rna_Koshi_GM_2023_rep2
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_GM_rep2


title: RNA-seq, leaf, Koshihikari, green manure, Year 2024, rep1

description:
Library name: rna_Koshi_GM_2024_rep1
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2024: 2024_GM_rep1


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2023, rep4

description:
Library name: rna_Koshi_CF_2023_rep4
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_CF_rep4


title: HEK293T_NTC_PCSK9_Tg3.rep1

description:
Library name: HEK293T_NTC_PCSK9_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: RNA-seq, leaf, Koshihikari, green manure, Year 2023, rep1

description:
Library name: rna_Koshi_GM_2023_rep1
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_GM_rep1


title: HEK293T_NTC_EMX1_Tg5.rep3

description:
Library name: HEK293T_NTC_EMX1_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2023, rep3

description:
Library name: rna_Koshi_CF_2023_rep3
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_CF_rep3


title: HEK293T_NTC_EMX1_Tg6.rep1

description:
Library name: HEK293T_NTC_EMX1_Tg6.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg6.rep3

description:
Library name: HEK293T_NTC_EMX1_Tg6.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg5.rep2

description:
Library name: HEK293T_NTC_EMX1_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg6.rep2

description:
Library name: HEK293T_NTC_EMX1_Tg6.rep2
Target.HEK293T.editing_frequency.txt


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2023, rep2

description:
Library name: rna_Koshi_CF_2023_rep2
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_CF_rep2


title: RNA-seq, leaf, Koshihikari, chemical fertilizer, Year 2023, rep1

description:
Library name: rna_Koshi_CF_2023_rep1
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_CF_rep1


title: HEK293T_NTC_PCSK9_Tg1.rep2

description:
Library name: HEK293T_NTC_PCSK9_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: RNA-seq, leaf, Koshihikari, green manure, Year 2023, rep4

description:
Library name: rna_Koshi_GM_2023_rep4
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2023: 2023_GM_rep4


title: WT

city: Philadelphia

first: Liang

last: Qiang

state: PA

address: 2900 Queen Lane room183

institute: Drexel University

description: Library name: Sample 1

library_source: transcriptomic single cell

data_processing:
Raw sequencing data were initially processed and aligned to GRCh38 (human) using Cell Ranger Count v7.0.1 (10X Genomics, Cloud analysis) and HDF5 files were generated. The HDF5 files were then uploaded to the Partek Flow software with scRNAseq toolkit (Illumina). Using a single cell QA/QC and a noise-reduction pipeline, the cells were further filtered to exclude low quality cells and features. The filtered set was then normalized using the recommended counts per million, add 1, log 2 transformation workflow. Principal component analysis (PCA) was performed on the filtered cells and further clustered using Louvain graph-based clustering algorithm using the top 20 PCAs and visualized using uniform manifold approximation and projection (UMAP). We then extracted the biomarkers for these clusters and used them to manually annotate the clusters.
Assembly: GRCh38-2024-A
Supplementary files format and content: .h5 files containing raw and filtered scRNA-seq count data.

source_name: organoids

extract_protocol:
Briefly, 3-month-old organoids were dissociated using 4 ml StemPro Accutase™ Cell Dissociation Reagent (Thermo Fisher Scientific, A1110501) for 12 minutes at 37°C. Subsequently, the organoids were quenched and treated briefly with DNAase I (Thermo Fisher Scientific, EN0521) and gently triturated using 2ml serological pipettes to generate single cell suspension in PBS with 1% BSA. Cell viability and count were assessed using trypan blue staining and a hemocytometer.
The cell suspension was then loaded onto Chromium next GEM Chip G (10x Genomics, 2000177) per manufacturer instructions, with a targeted cell recovery of 5000-10000 cells. Post GEM formation, the samples were subjected to reverse transcription, amplification, fragmentation and clean-ups, as recommended by the manufacturer. We then performed Illumina library preparation using the Dual Index plate TT Set A (10X Genomics, 3000431; Plate, 15535894). The subsequent library was then sequenced using NovaSeq6000 at a depth of 25000-30000 paired end reads per cell.

value: organoids

value: iPSC

value: Mixed


title: Trmt6 KO rep3

city: Hangzhou

first: Aiwei

last: Wu

state: Zhejiang

address: 2318 Yuhangtang Road

department: School of Basic Medical Sciences

institute: Hangzhou Normal University

description: Library name: Sample6

data_processing:
Sequencing reads were demultiplexed, quality controlled by fastp (version 0.21.0), and merged by FLASH (version 1.2.7). Shortly, reads with adaptor sequences and low-quality bases (quality score <20) were trimmed. Truncated reads shorter than 50 bp and reads containing ambiguous nucleotides were discarded. Subsequently, the paired-end reads were merged according to the minimum overlap of 10 bp with maximum mismatch ratio of 0.2 in the overlapping region. Only merged sequences were retained for downstream analyses. The UPARSE algorithm was used to cluster sequences with a 97% similarity cutoff, while chimeric sequences were identified and removed. Next, the taxonomy of each OTU representative sequence was assigned by using RDP Classifier against the reference database SILVA138 with a minimum confidence score of 0.7. Rarefaction was performed in order to compare the abundance of OTUs across samples.
Assembly: SILVA138
Supplementary files format and content: raw counts
Library strategy: 16S rRNA-seq

organism: Mus musculus

source_name: stool

extract_protocol:
Microbial DNA was extracted from fecal samples using an E.Z.N.A.® soil DNA Kit (Omega Bio-tek, Norcross, GA), according to the manufacturer ’s protocols.
The V3-V4 hypervariable regions of the bacterial 16S rRNA gene were amplified with the primers 338F (5’-ACTCCTACGGGAGGCAGCAG-3’) and 806R (5’-GGACTACHVGGGTWTCTAAT-3’) by a thermocycler PCR system (GeneAmp 9700, ABI, Foster, CA, United States). The PCR reactions were as follows: denaturation at 95°C for 3 min, 27 cycles of denaturation at 95°C for 30 s, annealing at 55°C for 30 s, elongation at 72°C for 45 s, extension at 72°C for 10 min, and ending at 4°C. Each 20 μL reaction mixture contained 4 μL of 5× TransStart FastPfu buffer, 2 μL of 2.5 mM dNTPs, 0.8 μL of each primer (5 μM), 0.4 μL TransStart FastPfu DNA Polymerase, and 10 ng template DNA. PCR was performed in triplicate. The PCR product was extracted from 2% agarose gel and purified using an AxyPrep DNA Gel Extraction Kit (Axygen Biosciences, Union City, CA), according to the manufacturer’s instructions, and quantified using Qubit 4 (Thermo Fisher, United States).

value: stool


title: HEK293T_NTC_EMX1_Tg5.rep1

description:
Library name: HEK293T_NTC_EMX1_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg4.rep1

description:
Library name: HEK293T_NTC_EMX1_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: Trmt6 KO rep2

description: Library name: Sample5


title: HEK293T_NTC_EMX1_Tg2.rep1

description:
Library name: HEK293T_NTC_EMX1_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg2.rep3

description:
Library name: HEK293T_NTC_EMX1_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg1.rep2

description:
Library name: HEK293T_NTC_EMX1_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg4.rep3

description:
Library name: HEK293T_NTC_EMX1_Tg4.rep3
Target.HEK293T.editing_frequency.txt


title: WT rep3

description: Library name: Sample3

value: wild type


title: HEK293T_NTC_EMX1_Tg1.rep1

description:
Library name: HEK293T_NTC_EMX1_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: A375-VR, Prop

city: Changsha

first: Yijing

last: He

address: Xiangya road

institute: Central South University

description: Library name: Sample 3

data_processing:
RNA quality was assessed by agarose gel electrophoresis. Libraries were prepared with the TruSeq Stranded mRNA LT Sample Prep Kit (Illumina) and sequenced on an Illumina HiSeq 2000 platform (paired-end 150 bp).
Assembly: tab-delimited text file incluldes raw counts for each sample
Supplementary files format and content: csv files include FPKM values for each sample

source_name: skin

extract_protocol:
Total RNA was extracted from A375-VR cells treated with DMSO or 20 µM propranolol for 24 h.
RNeasy Mini Kit (Qiagen, CAT No.74104).

value: skin

value: Tumor cell


title: A375, Prop

description: Library name: Sample 1


title: A375-VR, DMSO

description: Library name: Sample 2


title: Trmt6 KO rep1

description: Library name: Sample4


title: WT rep2

description: Library name: Sample2


title: HEK293T_NTC_VEGFA_Tg2.rep1

description:
Library name: HEK293T_NTC_VEGFA_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: SX

description: Library name: Sample 2

value: SPAST S245X


title: MC4100 λlacZ-mEYFP, IP

city: Heidelberg

first: Günter

last: Kramer

address: Im Neuenheimer Feld 329

country: Germany

institute: Center for Molecular Biology of Heidelberg University (ZMBH)

description: Library name: SeRP_lacZ-mEYFP_IP

data_processing:
The 3' adaptor sequences were trimmed form demultiplexed raw read sequencing files with Cutadapt (v1.13) with the following command for NextSeq550 files: cutadapt --cores=4 -q20 -m23 --discard-untrimmed -O6 -a ATCGTAGATCGGAAGAGCACACGTCTGAACTCCAGTCAC -o <path_to_output>.fastq.gz <path_to_input>.fastq.gz. For samples sequenced on HiSeq2000 the following command was used: cutadapt --cores=4 -q20 -m23 --discard-untrimmed -O6 -a CTGTAGGCACCATCAATTCGTATGCCGTCTTCTGCTTG -o <path_to_output>.fastq.gz <path_to_input>.fastq.gz
Unique molecular identifiers (UMIs) were extracted from each read for the downstream analysis using a custom Julia script (available as supplement information in Bertolini et al., 2021) with the following command: julia <path_to_script>/Script1.jl <path_to_input>.fastq.gz <path_to_output>.fastq.gz --umi3 5 --umi5 2. SeRP samples did not contain UMI sequences in the adaptors, therefore this step was not included.
Reads were aligned to the E. coli genome using bowtie.
All reads aligning to the coding sequence (CDS) were assigned to the p-site via a custom Julia script (available as supplement information in Bertolini et al., 2021). p-site assigned reads were used for all downstream analysis.
Assembly: NC_000913
Supplementary files format and content: HDF5 files containing raw reads assigned to ribosomal P-sites, organised by coding sequence (CDS). Depending on the library preparation method PCR duplicates are removed based on the unique molecular identifier (UMI).
Library strategy: Ribo-Seq

organism: Escherichia coli

source_name: bacterial cell

growth_protocol: Cells were grown in EZ RDM. For lacZ-mEYFP SeRP, expression was induced with 10 uM IPTG 15 min before harvesting. For DiSP, endogenous lacZ expression was induced with by lactose. Cells were harvested by rapid filtration through a 0.2 um nitrocellulose membrane, scraped of rapidly and plunged into liquid nitrogen.

extract_protocol:
Ribosomes were purifed by sucrose density ultracentrifugation (SeRP total sample), affinity purification (SeRP IP sample) or sucrose gradient ultracentrifugation (DiSP monosome and disome samples). RNA from ribosome fractions was extracted using the hot acid phenol method as previously described (DOI: 10.1038/s41596-019-0185-z)
SeRP libraries were prepared as previosly described (DOI: 10.1038/nprot.2013.133). DiSP libraries were prepared as previously publsihed (DOI: 10.1038/s41596-019-0185-z)

tag: strain

value: bacterial cell


title: HEK293T_NTC_CXCR4_Tg3.rep3

description:
Library name: HEK293T_NTC_CXCR4_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: MC4100 λlacZ-mEYFP, monosome fraction

description: Library name: SeRP_lacZ-mEYFP_Total


title: HEK293T_NTC_CXCR4_Tg3.rep1

description:
Library name: HEK293T_NTC_CXCR4_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: TC32-MMA-100nM-18hr-biolrep2

city: Ann Arbor

first: Patrick

middle: J

last: Grohar

state: MI

address: 1600 Huron Pkwy

institute: University of Michigan Medical School

description: Library name: GFGRO100B

data_processing:
Sequence quality by FASTQc
low quality sequence removed with cutadapt v2.10
aligned with STARv2.7.1
log2 ratios determined with deeptools
Assembly: HG38 with STAR v2.7.1a
Supplementary files format and content: FASTq

molecule: nuclear RNA

growth_protocol: RPMI with 10% FBS and P/S

extract_protocol:
Purified on column
NEV Next Small RNA library

treatment_protocol: Plate, recover overnight, apply drug for described times

value: Ewing Sarcoma

value: 100 nmol/L Mithramycin for 18 hours

tag: batch


title: HEK293T_NTC_EMX1_Tg4.rep2

description:
Library name: HEK293T_NTC_EMX1_Tg4.rep2
Target.HEK293T.editing_frequency.txt


title: TC32-MMA-100nM-18hr-biolrep1

description: Library name: GFGRO100A

value: WT


title: TC32-solvent-18hr-biolrep3

description: Library name: GFGROSolC

value: Solvent Control (PBS 0.01%)


title: HEK293T_NTC_CXCR4_Tg1.rep3

description:
Library name: HEK293T_NTC_CXCR4_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_CXCR4_Tg3.rep2

description:
Library name: HEK293T_NTC_CXCR4_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg5.rep3

description:
Library name: HEK293T_NTC_ALDH1A3_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: TC32-solvent-18hr-biolrep1

description: Library name: GFGROSolA


title: HEK293T_NTC_CXCR4_Tg2.rep1

description:
Library name: HEK293T_NTC_CXCR4_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_CXCR4_Tg2.rep3

description:
Library name: HEK293T_NTC_CXCR4_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg1.rep3

description:
Library name: HEK293T_NTC_EMX1_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: TC32-MMA-100nM-18hr-biolrep3

description: Library name: GFGRO100C


title: HEK293T_NTC_ALDH1A3_Tg5.rep1

description:
Library name: HEK293T_NTC_ALDH1A3_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_EMX1_Tg2.rep2

description:
Library name: HEK293T_NTC_EMX1_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg5.rep2

description:
Library name: HEK293T_NTC_ALDH1A3_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg4.rep3

description:
Library name: HEK293T_NTC_ALDH1A3_Tg4.rep3
Target.HEK293T.editing_frequency.txt


title: TC32-solvent-72hr-biolrep2

description: Library name: 32SB

value: Solvent Control (PBS 0.005%)


title: RNA-seq, leaf, Koshihikari, green manure, Year 2024, rep3

description:
Library name: rna_Koshi_GM_2024_rep3
column name in Koshi_CF_GM_RNA_rawdata_UniqueExonReads_2024: 2024_GM_rep3

value: leaf

value: GM


title: HEK293T_NTC_CXCR4_Tg1.rep1

description:
Library name: HEK293T_NTC_CXCR4_Tg1.rep1
Target.HEK293T.editing_frequency.txt

value: Kidney

value: Human embryonic kidney cells


title: TC32-solvent-72hr-biolrep1

description: Library name: 32SA


title: TC32-MMA-20nM-72hr-biolrep2

description: Library name: 3272B

value: 20 nmol/L Mithramycin for 72 hours


title: HEK293T_NTC_CXCR4_Tg1.rep2

description:
Library name: HEK293T_NTC_CXCR4_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg4.rep2

description:
Library name: HEK293T_NTC_ALDH1A3_Tg4.rep2
Target.HEK293T.editing_frequency.txt


title: TC32-solvent-72hr-biolrep3

description: Library name: 32SC


title: WT rep1

description: Library name: Sample1


title: HEK293T_NTC_ALDH1A3_Tg3.rep2

description:
Library name: HEK293T_NTC_ALDH1A3_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: TC32-MMA-20nM-72hr-biolrep1

description: Library name: 3272A


title: HEK293T_NTC_ALDH1A3_Tg3.rep1

description:
Library name: HEK293T_NTC_ALDH1A3_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg4.rep1

description:
Library name: HEK293T_NTC_ALDH1A3_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg3.rep3

description:
Library name: HEK293T_NTC_ALDH1A3_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: Hs15D34_G02b (MS321_098)

city: Kyoto

first: Yukihiro

last: Yabuta

state: Kyoto

address: Yoshida-Konoe-cho, Sakyo-ku

department: Anatomy and Cell Biology

institute: Kyoto University, Graduate school of medicine

description: Library name: Sample295

data_processing:
The genome sequence and transcript annotation (GRCh38.p12) were downloaded from the NCBI ftp site.
SC3-seq read only the 3’ end of the transcripts, so that the expression levels were calculated as genes (Entrez genes) but not mRNAs.
Read trimming, mapping, and estimation of expression levels were performed using cutadapt (v1.18), tophat2 (v2.1.1), and HTseq (v0.11.0), as described previously (Mizuta et al., 2022; Nakamura et al., 2016).
Expression levels in reads per million mapped reads (RPM) were used for the analysis.
Assembly: GRCh38.p12
Supplementary files format and content: tab-delimited text files include RPM values for each Sample

source_name: Ovary

growth_protocol: For in vitro growth culture (IVG), some of the human ovaries were used after informed consent from participants undergoing ovariectomy for clinical indication.  Under a stereomicroscope, secondary or preantral follicles were mechanically isolated from ovaries in handling medium, and using a glass capillary, transferred onto a Millicell membrane insert (Merck, PICM03050) in a 35-mm dish with 2 ml follicle culture medium outside of the membrane and 1 ml on the membrane.  Follicles were cultured in aMEM (GIBCO, 12571063) supplemented with 6% Quinn’s Advantage Serum Protein Substitute (CooperSurgical, ART-3011) or 5% FBS, 0.1 U/ml human urinary follicle stimulating hormone (uFSH; ASKA, 123-16188-6), 2 mM L-glutamine (GIBCO, 25030081), 150 mM Ascorbic Acid (Sigma-Aldrich, A4403), 1x Insulin-Transferrin-Selenium (GIBCO, 41400045), 1x MEM Non-Essential Amino Acids Solution (GIBCO, 11140050), 1 mM Sodium Pyruvate (GIBCO, 11360070), 0.5 mg/ml bovine fetuin (Sigma-Aldrich, F2379), 100 U/mL penicillin, and 0.1 mg/mL streptomycin (GIBCO, 15070063), and 2% polyvinylpyrrolidone (Wako, 162-17042Follicles were cultured at 37℃, 5% CO2 and 95% air in an incubator, and half of the volume of medium were changed every two days under stereomicroscope.  The collagenase treatment was performed on day3-4 to remove the tissue outside the basal lamina for improving the survival of the follicles. 　For collagenase treatment, follicles were incubated in collagenase solution [L-15 (Sigma-Aldrich, L5520) containing 30% FBS, 0.1% Collagenase I (Worthington Biochemicals, LS004294), 100 U/mL penicillin, and 0.1 mg/mL streptomycin]. 　The incubation was terminated by wash with L-15 handling medium [L-15 containing 5% FBS, 100 U/mL penicillin, and 0.1 mg/mL streptomycin], and follicles were transferred into follicle isolation medium [L-15 containing 0.4% polyvinylpyrrolidone, 100 U/mL penicillin, and 0.1 mg/mL streptomycin] for mechanical trimming of tissue outside the basal lamina with 27G needle or fine tungsten needle (FST, 10130-05).

extract_protocol:
Collected human ovaries, COCs and cultured follicles were placed in handling medium [DMEM/F-12 with HEPES (GIBCO, 11330057) containing 10% FBS (GIBCO, 10437028), 100 U/mL penicillin, and 0.1 mg/mL streptomycin (GIBCO, 15070063)].  For isolating small follicles (primordial ~ preantral follicles) from human ovaries, the ovarian cortical pieces were cut into 1 mm pieces after removal of medullary tissues. Then the tissue pieces were digested by a mixed digestion medium [aMEM (GIBCO, 12571063), 0.04 mg/ml Liberase DH (Roche, 5401054001), 10 IU/ml DNase I (Sigma-Aldrich, DN25)] for 20-75 min on a shaker at 37℃.  The incubation was terminated by wash with handling medium, and small follicles were manually collected.  Isolated follicles and COCs were photographed, followed by the dissociation process of oocytes and GCs.  Follicles and COCs were individually placed in 30 ml Accutase (Sigma-Aldrich, A6964) drops on a dish warmed by 37℃ plate, and oocytes and GCs were dissociated by pipetting up and down in a pulled fine glass capillary (Sutter Instrument, B100-75-10) with 30-120 mm in diameter, depending on the oocyte size.  For each follicle, about 15 GCs in the immediate vicinity of the oocyte were collected because of low abundancy of mRNA in these cells.  For primordial follicles, 15 GCs may not be obtained from a single follicle, in which case two or three primordial follicle-derived GCs were added together to make one sample.  At last, zona pellucida of GV/MII oocytes were removed by treating with acidic Tyrode's solution (Sigma-Aldrich, T1788) to obtain naked oocytes without contamination of GCs.  The removal of surrounding GCs from oocytes was confirmed under stereomicroscope (Leica, S8 APO) and inverted microscope (Olympus, IX71).  Dissociated oocytes and GCs from follicle grown in vivo and in vitro were manually picked up using glass capillaries under a stereomicroscope, and were used for SC3-seq.
The cDNA synthesis and amplification were performed as described previously (Kurimoto et al., 2006; Kurimoto et al., 2007; Nakamura et al., 2016; Nakamura et al., 2015). The quality of the amplified cDNA was measured by a SYBR real-time PCR method (CFX384 Touch Real-Time PCR Detection System, BIO-RAD; Power SYBR Green PCR Master Mix, Applied Biosystems, 4367659) targeting the PPIA, GAPDH, DDX4, DAZL, FOXL2, GJA1, and AMHR2 genes. The SC3-seq libraries were constructed as described previously (Ishikura et al., 2021; Mizuta et al., 2022; Nakamura et al., 2016; Nakamura et al., 2015; Okamoto et al., 2021), and the sequencing was performed on the Illumina NextSeq 500/550 plat-form with a NextSeq 500/550 high output kit v.2 (75 cycles) (FC-404-2005; Illumina).

treatment_protocol: Human ovaries were collected after informed consent from participants undergoing ovariectomy for clinical indication.  To retrieve COCs from antral follicles, COCs were aspirated with 27G needles or extruded from the incision of follicles with micro scissors.

value: Ovary

value: Granulosa cell

value: wildtype

value: IVG culture for 34 days

tag: group

value: 15 Cumulus cells, 34 days cultured preantral follicle (follicle No.2), Hs15 (38y, benign ovarian tumor)


title: HEK293T_NTC_CXCR4_Tg2.rep2

description:
Library name: HEK293T_NTC_CXCR4_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_ALDH1A3_Tg2.rep2

description:
Library name: HEK293T_NTC_ALDH1A3_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: Hs15D34_O02 (MS321_097)

description: Library name: Sample293

value: Oocyte

value: Oocyte (98 um), 34 days cultured preantral follicle (follicle No.2), Hs15 (38y, benign ovarian tumor)


title: Hs15D34_G02a (MS305_076)

description: Library name: Sample294


title: HEK293T_NTC_ALDH1A3_Tg2.rep3

description:
Library name: HEK293T_NTC_ALDH1A3_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: Hs15D34_G03 (MS321_227)

description: Library name: Sample297

value: 15 Cumulus cells, 34 days cultured preantral follicle (follicle No.3), Hs15 (38y, benign ovarian tumor)


title: Hs13D43_O02 (MS305_202)

description: Library name: Sample290

value: IVG culture for 43 days

value: Oocyte (102 um), 43 days cultured preantral follicle (follicle No.2), Hs13 ( 40y, endometrial cancer, intact ovary)


title: HEK293T_NTC_ALDH1A3_Tg1.rep2

description:
Library name: HEK293T_NTC_ALDH1A3_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: Hs15D34_O01 (MS321_223)

description: Library name: Sample292

value: Oocyte (107 um), 34 days cultured preantral follicle (follicle No.1), Hs15 (38y, benign ovarian tumor)


title: Hs13D43_G01c (MS293_012)

description: Library name: Sample289

value: 15 Cumulus cells, 43 days cultured preantral follicle (follicle No.1-3), Hs13 ( 40y, endometrial cancer, intact ovary)


title: Hs13D43_G02 (MS293_016)

description: Library name: Sample291

value: 15 Cumulus cells, 43 days cultured preantral follicle (follicle No.2-1), Hs13 ( 40y, endometrial cancer, intact ovary)


title: HEK293T_NTC_ALDH1A3_Tg1.rep3

description:
Library name: HEK293T_NTC_ALDH1A3_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: Hs15D34_O03 (MS321_226)

description: Library name: Sample296

value: Oocyte (94 um), 34 days cultured preantral follicle (follicle No.3), Hs15 (38y, benign ovarian tumor)


title: HEK293T_NTC_ALDH1A3_Tg2.rep1

description:
Library name: HEK293T_NTC_ALDH1A3_Tg2.rep1
Target.HEK293T.editing_frequency.txt

value: Kidney


title: TC32-solvent-18hr-biolrep2

description: Library name: GFGROSolB

value: Ewing Sarcoma

value: WT

value: Solvent Control (PBS 0.01%)


title: HEK293T_IscB_omegaRNA_VEGFA_Tg6.rep3

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg6.rep3
Target.HEK293T.editing_frequency.txt

value: Human embryonic kidney cells


title: HEK293T_NTC_ALDH1A3_Tg1.rep1

description:
Library name: HEK293T_NTC_ALDH1A3_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: Hs13D43_G01b (MS293_011)

description: Library name: Sample288

value: Ovary

value: Granulosa cell

value: wildtype

value: 15 Cumulus cells, 43 days cultured preantral follicle (follicle No.1-2), Hs13 ( 40y, endometrial cancer, intact ovary)


title: HEK293T_IscB_omegaRNA_VEGFA_Tg6.rep1

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg6.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg5.rep1

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg6.rep2

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg6.rep2
Target.HEK293T.editing_frequency.txt


title: Hs7_G11 (MS252_233)

description: Library name: Sample285

value: 10-20 granulosa cells, primordial~primary follicle, adult human ovary, Hs7, age17, mucinous borderline tumor of Lt. ovary (post cystectomy)


title: Hs13D43_O01 (MS305_201)

description: Library name: Sample286

value: Oocyte

value: Oocyte (104 um), 43 days cultured preantral follicle (follicle No.1), Hs13 ( 40y, endometrial cancer, intact ovary)


title: HEK293T_IscB_omegaRNA_VEGFA_Tg4.rep2

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg4.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg5.rep2

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: Hs7_G09 (MS252_230)

description: Library name: Sample282


title: Hs7_G08 (MS252_228)

description: Library name: Sample280


title: Hs7_O10 (MS252_231)

description: Library name: Sample283

value: oocyte, primordial~primary  follicle, adult human ovary, Hs7, age17, mucinous borderline tumor of Lt. ovary (post cystectomy)


title: Hs7_G10 (MS252_232)

description: Library name: Sample284


title: HEK293T_IscB_omegaRNA_VEGFA_Tg5.rep3

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: Hs7_O08 (MS248_108)

description: Library name: Sample279


title: HEK293T_IscB_omegaRNA_VEGFA_Tg4.rep3

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg4.rep3
Target.HEK293T.editing_frequency.txt


title: Hs7_O07 (MS252_227)

description: Library name: Sample278


title: Hs7_O09 (MS252_229)

description: Library name: Sample281


title: Hs7_G05 (MS252_224)

description: Library name: Sample275

value: 10-20 granulosa cells, primordial follicle, adult human ovary, Hs7, age17, mucinous borderline tumor of Lt. ovary (post cystectomy)


title: Hs7_O06 (MS252_225)

description: Library name: Sample276

value: oocyte, primordial  follicle, adult human ovary, Hs7, age17, mucinous borderline tumor of Lt. ovary (post cystectomy)


title: HEK293T_IscB_omegaRNA_VEGFA_Tg3.rep1

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg3.rep3

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg4.rep1

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: Hs13D43_G01a (MS293_010)

description: Library name: Sample287

value: IVG culture for 43 days

value: 15 Cumulus cells, 43 days cultured preantral follicle (follicle No.1-1), Hs13 ( 40y, endometrial cancer, intact ovary)


title: HEK293T_IscB_omegaRNA_VEGFA_Tg2.rep1

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg2.rep1
Target.HEK293T.editing_frequency.txt

value: Kidney


title: Hs7_G04 (MS252_222)

description: Library name: Sample273

value: 10-20 granulosa cells, primary follicle, adult human ovary, Hs7, age17, mucinous borderline tumor of Lt. ovary (post cystectomy)


title: HEK293T_IscB_omegaRNA_VEGFA_Tg2.rep2

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg2.rep3

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg1.rep1

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: Hs7_O03 (MS252_219)

description: Library name: Sample270

value: oocyte, primary  follicle, adult human ovary, Hs7, age17, mucinous borderline tumor of Lt. ovary (post cystectomy)


title: HEK293T_IscB_omegaRNA_PCSK9_Tg3.rep2

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: Hs7_O05 (MS252_223)

description: Library name: Sample274


title: HEK293T_IscB_omegaRNA_VEGFA_Tg1.rep2

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_PCSK9_Tg3.rep3

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: Hs7_O04 (MS252_221)

description: Library name: Sample272


title: Hs7_G01 (MS252_217)

description: Library name: Sample267


title: HEK293T_IscB_omegaRNA_PCSK9_Tg2.rep3

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_NTC_PCSK9_Tg1.rep3

description:
Library name: HEK293T_NTC_PCSK9_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: HS11_O12 (MS252_216)

description: Library name: Sample264

value: oocyte, primary  follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_PCSK9_Tg2.rep2

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg2.rep2
Target.HEK293T.editing_frequency.txt

value: Human embryonic kidney cells


title: Hs7_G06 (MS252_226)

description: Library name: Sample277

value: Ovary


title: Hs7_G03 (MS252_220)

description: Library name: Sample271

value: Granulosa cell


title: HEK293T_IscB_omegaRNA_VEGFA_Tg1.rep3

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_VEGFA_Tg3.rep2

description:
Library name: HEK293T_IscB_omegaRNA_VEGFA_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: HS11_G10 (MS248_090)

description: Library name: Sample261

value: wildtype

value: 10-20 granulosa cells, primordial follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: Hs7_G02 (MS252_218)

description: Library name: Sample269


title: HEK293T_IscB_omegaRNA_PCSK9_Tg2.rep1

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_O11 (MS248_091)

description: Library name: Sample262


title: HEK293T_IscB_omegaRNA_PCSK9_Tg3.rep1

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_G11 (MS248_092)

description: Library name: Sample263

value: 10-20 granulosa cells, primary follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_PCSK9_Tg1.rep1

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_O10 (MS248_089)

description: Library name: Sample260

value: Oocyte

value: oocyte, primordial  follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: Hs7_O01 (MS248_095)

description: Library name: Sample266


title: HS11_G09 (MS248_088)

description: Library name: Sample259


title: HS11_G12 (MS248_094)

description: Library name: Sample265


title: HEK293T_IscB_omegaRNA_PCSK9_Tg1.rep3

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg6.rep1

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg6.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg5.rep3

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: HS11_O08 (MS248_085)

description: Library name: Sample256

value: oocyte, secondary  follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_EMX1_Tg5.rep2

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: HS11_G08 (MS248_086)

description: Library name: Sample257

value: 10-20 granulosa cells, secondary follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_EMX1_Tg6.rep3

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg6.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg5.rep1

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg5.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg4.rep3

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg4.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg4.rep2

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg4.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg6.rep2

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg6.rep2
Target.HEK293T.editing_frequency.txt


title: HS11_O06 (MS248_081)

description: Library name: Sample252

value: oocyte, preantral  follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HS11_G06 (MS248_082)

description: Library name: Sample253

value: 10-20 granulosa cells, preantral follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HS11_G07 (MS248_084)

description: Library name: Sample255


title: HS11_O05 (MS251_050)

description: Library name: Sample250


title: Hs7_O02 (MS248_097)

description: Library name: Sample268


title: HEK293T_IscB_omegaRNA_EMX1_Tg4.rep1

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_O09 (MS248_087)

description: Library name: Sample258


title: HEK293T_IscB_omegaRNA_EMX1_Tg2.rep3

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg1.rep2

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_PCSK9_Tg1.rep2

description:
Library name: HEK293T_IscB_omegaRNA_PCSK9_Tg1.rep2
Target.HEK293T.editing_frequency.txt


title: HS11_O07 (MS248_083)

description: Library name: Sample254


title: HEK293T_IscB_omegaRNA_EMX1_Tg1.rep1

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_O04 (MS251_040)

description: Library name: Sample248

value: oocyte, COC aspirated from large antral follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_EMX1_Tg1.rep3

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg1.rep3
Target.HEK293T.editing_frequency.txt

value: Kidney


title: HEK293T_IscB_omegaRNA_EMX1_Tg2.rep2

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: HS11_G02 (MS251_037)

description: Library name: Sample245

value: 10-20 granulosa cells, COC isolated from about 1mm antral follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_CXCR4_Tg2.rep2

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_CXCR4_Tg2.rep3

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg2.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_CXCR4_Tg3.rep1

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_EMX1_Tg2.rep1

description:
Library name: HEK293T_IscB_omegaRNA_EMX1_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_O01 (MS251_034)

description: Library name: Sample242

value: oocyte, COC isolated from about 1mm antral follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HS11_G04 (MS251_049)

description: Library name: Sample249

value: 10-20 granulosa cells, COC aspirated from large antral follicle, adult human ovary, Hs11, age25, gender identity disorder (testosterone medication until 6w before operation)


title: HS11_O03 (MS251_038)

description: Library name: Sample246


title: Hs10_G12 (MS251_033)

description: Library name: Sample241

value: 10-20 granulosa cells, primordial follicle, adult human ovary, Hs10, age23, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_CXCR4_Tg1.rep2

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg1.rep2
Target.HEK293T.editing_frequency.txt

value: Human embryonic kidney cells


title: HEK293T_IscB_omegaRNA_CXCR4_Tg1.rep3

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg1.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_CXCR4_Tg3.rep3

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: Hs10_O11 (MS251_030)

description: Library name: Sample238

value: Ovary

value: oocyte, primordial  follicle, adult human ovary, Hs10, age23, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_CXCR4_Tg3.rep2

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg3.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_CXCR4_Tg1.rep1

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg1.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_G05 (MS251_051)

description: Library name: Sample251

value: Granulosa cell

value: wildtype


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg5.rep3

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg5.rep3
Target.HEK293T.editing_frequency.txt


title: HS11_G03 (MS251_039)

description: Library name: Sample247


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg4.rep3

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg4.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_CXCR4_Tg2.rep1

description:
Library name: HEK293T_IscB_omegaRNA_CXCR4_Tg2.rep1
Target.HEK293T.editing_frequency.txt


title: HS11_O02 (MS251_036)

description: Library name: Sample244

value: Oocyte


title: Hs10_G09 (MS251_027)

description: Library name: Sample235

value: 10-20 granulosa cells, primary follicle, adult human ovary, Hs10, age23, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg4.rep2

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg4.rep2
Target.HEK293T.editing_frequency.txt


title: Hs10_G10 (MS251_029)

description: Library name: Sample237


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg3.rep3

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg3.rep3
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg3.rep1

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg3.rep1
Target.HEK293T.editing_frequency.txt


title: Hs10_G11 (MS251_031)

description: Library name: Sample239


title: Hs10_G06 (MS251_021)

description: Library name: Sample229

value: 10-20 granulosa cells, preantral follicle, adult human ovary, Hs10, age23, gender identity disorder (testosterone medication until 6w before operation)


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg5.rep2

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg5.rep2
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg4.rep1

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg4.rep1
Target.HEK293T.editing_frequency.txt


title: HEK293T_IscB_omegaRNA_ALDH1A3_Tg2.rep2

description:
Library name: HEK293T_IscB_omegaRNA_ALDH1A3_Tg2.rep2
Target.HEK293T.editing_frequency.txt


title: Hs10_O10 (MS251_028)

description: Library name: Sample236