title: SuperArray GEArray Q Series Mouse Nitric Oxide Gene Array
status: Public on Apr 09 2004
contact.city: Frederick
contact.first: SuperArray
contact.last: Bioscience Corporation
contact.email: support@superarray.net
contact.state: MD
contact.address: Suite 101, 7320 Executive Way
contact.country: USA
contact.institute: Technical Support
contact.phone: 301-682-9200
organism: Mus musculus
description: The GEArray Q Series Mouse Nitric Oxide Gene Array contains 96 genes whose expression is controlled by or involved in signaling by the second messenger nitric oxide (NO). The list of genes on this array, shown below, demonstrates the variety of targets downstream of NO. They include chemokines and cytokines, ECM and adhesion molecules, growth factors and hormones and their receptors, transcription factors and many others. NO is very reactive, short acting, and generates reactive nitrogen species (RNS) that help NO mediate its signal transduction. NO/RNS-regulated gene expression involves different mechanisms including mRNA stabilization, translation modulation, and covalent modification of proteins. Imbalances in the levels of extracellular and intracellular NO occur in many physiological and pathophysiological processes. The cellular processes regulated by NO/RNS include metabolism and endogenous defense mechanisms against a variety of stresses and diseases. Through a simple side-by-side hybridization using your experimental RNA samples and the arrays and reagents provided in the kit, you can simultaneously determine the expression profile of the following NO-regulated genes.
  Catalog number MM-034 (Superarray, Frederick, MD)
  Platform_weblink: http://www.superarray.com/home.php
manufacture_protocol: see manufacturer's web site