title: CCF Cancer cDNA Array
status: Public on Aug 14 2004
contact.city: Cleveland
contact.first: Wenliang
contact.last: Li
contact.email: williab@ccf.org
contact.state: OH
contact.address: 9500 Euclid Ave
contact.department: Department of Cancer Biology
contact.country: USA
contact.web_link: http://www.lerner.ccf.org/labs/williams
contact.institute: Lerner Research Inst., The Cleveland Clinic
contact.phone: 216-445-9652
organism: Homo sapiens
description: The Cancer cDNA Array contains probes for 9241 cDNA clones corresponding to ~4900 unigenes or unclustered ESTs relevant to cancer biology. These include:  1) 1800 genes implicated in metastasis or tumor development in general from the literature and Affymetrix cancer G110 array (www.affymetrix.com/analysis/index.affx); 2) 1809 genes involved in kidney development (golgi.ana.ed.ac.uk/kidhome.html) or showing more than 3-fold variation of expression among 4 primary Wilms tumors and fetal kidney in our previous Affymetrix GeneChip experiments (unpublished data); 3) 1400 potential downstream targets of p53 transcriptional regulation; 4) 950 genes with AU-rich elements in their 3’ and/or 5’ UTR; 5) 1245 cytokine responsive genes, genes for zinc finger proteins or genes implicated in apoptosis.