NIH_SPENDING_CATS: Cancer;Cancer Genomics;Cervical Cancer;Clinical Research;Genetics;Human Genome;Infectious Diseases;Prevention;Sexually Transmitted Infections;Women's Health Research

PI_NAMEs: SCHIFFMAN, MARK  (contact)

PROJECT_TERMS: Acquired Immunodeficiency Syndrome;Address;Africa South of the Sahara;Algorithms;Artificial Intelligence;Biological Assay;California;Cancer Etiology;cancer risk;carcinogenesis;Carcinogens;Cervical;cervical cancer prevention;Cervical Cancer Screening;cervical carcinogenesis;child bearing;Clinical;clinical risk;Clonality;cohort;Coitus;Collaborations;Country;Cytology;Data;design;Division of Cancer Epidemiology and Genetics;DNA;Epigenetic Process;Etiology;Excision;experience;Genes;Genetic;Genome;Genomics;Goals;Guidelines;handheld mobile device;healing;High Prevalence;Histology;HIV;Human;Human Papillomavirus;Image;Immune response;immunosuppressed;improved;Invaded;Learning;Lesion;Link;Malignant neoplasm of cervix uteri;Malignant Neoplasms;Methods;Methylation;microbiome;Microscopic;molecular marker;Monitor;Natural History;New Mexico;Nigeria;Online Systems;open source;Outcome;Penetrance;Population;population based;premalignant;Prevalence;prevent;Recurrence;Registries;Research;Research Project Grants;Reserve Cell;Resource-limited setting;Risk;Risk Assessment;risk prediction;risk prediction model;screening;software systems;Source;Specimen;Syndrome;Testing;Translating;Translations;transmission process;treatment strategy;Triage;United States National Library of Medicine;Vaccination;Variant;viral genomics;Virus;Visual;Visualization;Woman;women's treatment

PROJECT_TITLE: Human Papillomavirus (HPV) Natural History, Genomics and Risk Assessment


ACTIVITY: ZIA

ADMINISTERING_IC: CA

ARRA_FUNDED: N

FUNDING_MECHANISM: INTRAMURAL RESEARCH

IC_NAME: NATIONAL CANCER INSTITUTE

NIH_SPENDING_CATS: Aging;Cancer;Clinical Research;Clinical Trials and Supportive Activities;Colorectal Cancer;Digestive Diseases;Lung;Lung Cancer;Ovarian Cancer;Prevention;Prostate Cancer;Rare Diseases;Urologic Diseases;Women's Health Research

ORG_NAME: DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS

PI_NAMEs: MOORE, STEVEN  (contact)

PROJECT_TERMS: aged;Benign Prostatic Hypertrophy;Biochemical;Blood;Cells;Cessation of life;clinical center;cohort;Collaborations;Colonic Polyps;Colorectal Cancer;Computers;Contracts;Data Collection;Data Set;Development;Disease;Division of Cancer Epidemiology and Genetics;Division of Cancer Prevention;effectiveness evaluation;Extramural Activities;follow-up;Genetic;indexing;Individual;Investigation;Malignant neoplasm of lung;Malignant neoplasm of ovary;Malignant Neoplasms;Medical Records;men;NCI Executive Committee;neoplasm registry;Participant;Pathologic;Population;Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial;Questionnaires;Randomized;Records;Research Personnel;Risk;Risk Factors;Saliva;Sampling Studies;Scientist;screening;Screening for Prostate Cancer;Study Subject;Support Contracts;Test Result;Tissues;Update;usual care arm;volunteer;Woman

PROJECT_TITLE: PLCO EEMS and Extended Follow Up


NIH_SPENDING_CATS: Cancer;Cervical Cancer;Clinical Research;Dental, Oral, and Craniofacial Disease;Digestive Diseases;Immunization;Infectious Diseases;Prevention;Rare Diseases;Sexually Transmitted Infections;Vaccine Related;Women's Health Research

PI_NAMEs: KREIMER, AIMEE  (contact)

PROJECT_TERMS: Address;Agreement;Anus;Biological;Cancer Etiology;cancer recurrence;carcinogenicity;Cervical;Cervix Uteri;cohort;conjunctiva;Cutaneous;Cytology;Data;Diagnosis;efficacy evaluation;Epidemiology;Evaluation;Genotype;Goals;Head and Neck Cancer;Head and Neck Neoplasms;HIV;Human;Human papilloma virus infection;Human Papilloma Virus-Related Malignant Neoplasm;Human Papillomavirus;Human papillomavirus 16;Human papillomavirus 18;immunosuppressed;Individual;Infection;Infection prevention;Infectious Agent;Larynx;malignant mouth neoplasm;Malignant neoplasm of cervix uteri;Malignant Neoplasms;men;Multiple Anatomic Sites;Natural History;Oral;oral HPV infection;Oropharyngeal;penis;Population;Prevalence;Preventive vaccine;prospective;Research;Risk;Role;sample collection;Site;Skin;Specimen;Testing;tumor;vaccine efficacy;vaccine trial;Vagina;Vulva;Work

PROJECT_TITLE: HPV and cancer at multiple anatomic sites


NIH_SPENDING_CATS: Cancer;Cervical Cancer;Clinical Research;Genetics;Immunization;Infectious Diseases;Prevention;Rare Diseases;Sexually Transmitted Infections;Vaccine Related;Women's Health Research

PROJECT_TERMS: Adenocarcinoma Cell;Affect;Antibodies;Case/Control Studies;Cervical;Cervical Adenocarcinoma;cervical cancer prevention;Cervix Neoplasms;cofactor;Cohort Studies;Contraceptive Usage;Development;DNA;epidemiology study;Etiology;Evaluation;Funding;GEM gene;Genes;Genetic;Genetic Polymorphism;Goals;Head and Neck Cancer;Histologic;Histology;HIV;Hormonal;Human papilloma virus infection;Human Papilloma Virus-Related Malignant Neoplasm;Human Papillomavirus;Immune;Immunity;Immunologic Factors;Individual;Infection;Knowledge;Lesion;Longitudinal Studies;Malignant neoplasm of anus;Malignant neoplasm of cervix uteri;Malignant Neoplasms;Menstrual cycle;Molecular Epidemiology;Mucosal Immunity;Natural History;novel;Oral Contraceptives;Predisposition;premalignant;Prevention;Prevention strategy;response;Risk Factors;Role;screening;Sex Behavior;Squamous cell carcinoma;Taiwan;Testing;Vaccination;Variant;Viral;Virus Diseases;Women's study;Work

PROJECT_TITLE: HPV, cervical neoplasia, and vaccination


NIH_SPENDING_CATS: Cancer;Clinical Research;Dental, Oral, and Craniofacial Disease;Genetics;Prevention

PI_NAMEs: ENGELS, ERIC A (contact)

PROJECT_TERMS: Affect;Antibodies;Antibody Specificity;Behavioral;cancer risk;Case/Control Studies;Caucasians;Childhood;China;Chinese;Chromosome 14;cigarette smoking;Clinical;Clinical Markers;CYP2E1 gene;Development;dietary;DNA Repair;DNA Repair Gene;Dust;Environmental Risk Factor;Enzymes;Ethnic Origin;Etiology;Evaluation;Exposure to;Family;Family Study;follow-up;Formaldehyde;GEM gene;Gene Expression;Gene Expression Profile;General Population;Genes;Genetic;Geography;high risk population;Human Herpesvirus 4;Immune;Immune Evasion;improved;Individual;Infection;Intake;Integration Host Factors;Loss of Heterozygosity;Malignant neoplasm of nasopharynx;Malignant Neoplasms;Nasopharyngeal Neoplasms;neoplastic cell;Nitrites;Nitrosamine Metabolism;Nitrosamines;Normal Cell;Occupational;Occupational Exposure;Pathogenesis;Pattern;Population;Risk;Risk Factors;Serology;Taiwan;telomere;Testing;Tissues;Variant;Viral;Weaning;Wood material

PROJECT_TITLE: Viral and Host Factors Associated with NPC


NIH_SPENDING_CATS: Cancer;Clinical Research;Digestive Diseases;Genetics;HIV/AIDS;Hematology;Infectious Diseases;Lymphatic Research;Lymphoma;Rare Diseases;Stomach Cancer

PI_NAMEs: RABKIN, CHARLES  (contact)

PROJECT_TERMS: Acquired Immunodeficiency Syndrome;AIDS-Related Lymphoma;antiretroviral therapy;Blood;Blood Cells;Chronic;Clonal Expansion;Cytokine Signaling;Data;Descriptive Epidemiology;Disease;Epstein-Barr Virus Infections;Etiology;General Population;Genes;Genetic Polymorphism;Genetic Variation;Helicobacter Infections;HIV Infections;Human Herpesvirus 4;Immunologic Epidemiology;Infection;infection related cancer;Inflammation;Investigation;Laboratories;Lymphocyte;Lymphoma;Malignant Neoplasms;malignant stomach neoplasm;Molecular;Morbidity - disease rate;Mucositis;Non-Hodgkin's Lymphoma;Outcome;Pathway interactions;Population Analysis;population based;Prospective cohort;Prospective, cohort study;Risk;Role;Source;tumor

PROJECT_TITLE: Molecular mechanisms of infection-related cancer


NIH_SPENDING_CATS: Cancer;Clinical Research;Dental, Oral, and Craniofacial Disease;Digestive Diseases;Infectious Diseases;Rare Diseases;Sexually Transmitted Infections

PI_NAMEs: CHATURVEDI, ANIL  (contact)

PROJECT_TERMS: cancer site;Cross-Sectional Studies;Etiology;Goals;Head and Neck Cancer;Human papilloma virus infection;Human Papillomavirus;Incidence;India;International;Lesion;malignant oropharynx neoplasm;molecular marker;National Health and Nutrition Examination Survey;Natural History;oral HPV infection;Population;Prevalence Study;Research Project Grants;screening;trend

PROJECT_TITLE: Studies of Head and Neck Cancers


NIH_SPENDING_CATS: Cancer;Cancer Genomics;Clinical Research;Dental, Oral, and Craniofacial Disease;Digestive Diseases;Genetics;Human Genome;Microbiome;Women's Health Research

PI_NAMEs: VOGTMANN, EMILY  (contact)

PROJECT_TERMS: 18 year old;Address;Adult;Antibiotic Therapy;Antibiotics;Behavioral;Biological Assay;C-reactive protein;Collection;Colon;colon microbiome;Demographic Factors;Diagnostic;Diet;Disease;Enrollment;Epidemiology;Functional Gastrointestinal Disorders;Future;gastrointestinal symptom;Heterogeneity;human disease;Human Microbiome;Individual;Individual Differences;inflammatory marker;Malignant Neoplasms;Measures;men;microbiome;microbiota;Oral;oral microbiome;Patient Self-Report;penile microbiome;penis;Questionnaires;Reproducibility;Rome;Sampling;Site;Skin;skin microbiome;Specimen;Techniques;Time;Vagina;vaginal microbiome;Woman

PROJECT_TITLE: Human microbiome and cancer


NIH_SPENDING_CATS: Biotechnology;Cancer;Cervical Cancer;Clinical Research;Clinical Trials and Supportive Activities;Dental, Oral, and Craniofacial Disease;Digestive Diseases;HPV and/or Cervical Cancer Vaccines;Immunization;Infectious Diseases;Orphan Drug;Prevention;Rare Diseases;Sexually Transmitted Infections;Vaccine Related;Women's Health Research

PROJECT_TERMS: Acquired Immunodeficiency Syndrome;Age;Antibodies;Antibody Avidity;Anus;Blinded;Cervical;Cervix Neoplasms;Cervix Uteri;Clinical;Collaborations;Communities;Costa Rica;Cytology;DNA;dosage;Dose;Effectiveness;efficacy evaluation;Enrollment;Evaluation;follow-up;Frequencies;Funding;Head and Neck Cancer;high risk;HIV Infections;HIV Seropositivity;Human papilloma virus infection;Human Papilloma Virus Vaccination;Human Papilloma Virus Vaccine;Human Papilloma Virus-Related Malignant Neoplasm;Human Papillomavirus;Human papillomavirus 16;Human papillomavirus 18;Immune response;immunogenic;immunogenicity;Immunologics;Infection;infection rate;Lesion;Malignant neoplasm of anus;Malignant neoplasm of cervix uteri;Malignant Neoplasms;Measures;Medical;men who have sex with men;Methodology;Molecular Conformation;Natural History;Oncogenic;oral HPV-positive head and neck cancers;Participant;Phase;Phylogenetic Analysis;Population;Population Group;premalignant;prevent;Preventative vaccination;Public Health;Randomized;Randomized, Controlled Trials;Research;Resource-limited setting;Safety;screening program;self assembly;Series;Site;Structural Protein;System;United States National Institutes of Health;unvaccinated;Vaccinated;Vaccination;vaccine formulation;vaccine trial;Vaccinee;Vaccines;Viral;virtual;Virus-like particle;Woman;Women's Health;Work

PROJECT_TITLE: HPV Vaccine Trial


NIH_SPENDING_CATS: Cancer;Clinical Research;Digestive Diseases;Digestive Diseases - (Gallbladder);Liver Cancer;Liver Disease;Rare Diseases

PI_NAMEs: KOSHIOL, JILL  (contact)

PROJECT_TERMS: Aflatoxins;Bile fluid;Biliary;biliary tract;Biliary Tract Cancer;Biochemical;Biological;Cancer Patient;case control;Chile;Cholelithiasis;cohort;Collection;Complement;Diet;DNA;drinking;Epidemiology;Etiology;Evaluation;Evaluation of Cancer Risk Factors;Gallbladder;Gender;Goals;Individual;insight;Investigation;Lesion;Longitudinal Studies;Malignant neoplasm of gallbladder;Malignant Neoplasms;Medical History;Molecular;multidisciplinary;Participant;Patients;Pilot Projects;Population;population based;prospective;Prospective Studies;Questionnaires;Random Allocation;Reproductive History;Risk Factors;Sampling;Serum;Smoking;Structure;Tissue Sample;Validation;Woman

PROJECT_TITLE: Etiology of Biliary Tract Cancer


NIH_SPENDING_CATS: Brain Cancer;Brain Disorders;Cancer;Childhood Obesity;Clinical Research;Congenital Structural Anomalies;Dietary Supplements;Nutrition;Obesity;Pediatric;Pediatric Cancer;Prevention;Radiation Oncology;Rare Diseases

PI_NAMEs: KITAHARA, CARI  (contact)

PROJECT_TERMS: Asthma;Back;Body mass index;cancer diagnosis;Cancer Patient;cancer subtypes;case control;Child;Childhood Leukemia;Chinese;Chronic Disease;cohort;community intervention;Conceptions;Country;County;Data;Data Set;Disease;effectiveness evaluation;Enrollment;Environmental Exposure;epidemiology study;Etiology;European;Evaluation;Family;feasibility testing;Folic Acid;folic acid supplementation;Gallbladder;Genetic;Hospitals;Incidence;Individual;intervention program;Interview;Life Style;Link;Malignant Childhood Neoplasm;Malignant neoplasm of brain;Malignant neoplasm of thyroid;Malignant Neoplasms;Mission;mortality;Mothers;Neural Tube Defects;Obesity;offspring;Persons;Pilot Projects;Play;Population Programs;Prospective Studies;Province;Publications;Publishing;Radiation Tolerance;rare cancer;Research;Risk;Risk Factors;Risk Reduction;Role;Sampling;Site;Thyroid Gland;tumor;waist circumference;Work

PROJECT_TITLE: Studies of other risk factors for radiosensitive tumors


NIH_SPENDING_CATS: Cancer;Clinical Research;Digestive Diseases;Esophageal Cancer;Prevention;Rare Diseases

PI_NAMEs: ABNET, CHRISTIAN  (contact)

PROJECT_TERMS: Adenocarcinoma;Algorithms;Androgens;Barrett Epithelium;Barrett Esophagus;Bile Acids and Salts;billing data;cancer epidemiology;cancer risk;Case/Control Studies;Cells;Chemicals;Clinical;clinical practice;cohort;Cohort Studies;comparative;Costs and Benefits;Data;data harmonization;Databases;Diagnosis;diagnostic biomarker;diagnostic value;Disease;disease natural history;disorder control;Endoscopy;Epithelial Cells;Epithelium;Equation;Esophageal Adenocarcinoma;Esophagitis;Esophagus;Estrogens;Etiology;Exposure to;follow-up;Gastroenterology;Gastroesophageal reflux disease;General Population;General Practices;genotoxicity;Goals;Hepatology;high risk;Hormones;Incidence;indexing;Individual;inflammatory marker;Journals;Laboratories;Lesion;Link;Malignant neoplasm of esophagus;Malignant Neoplasms;Manuscripts;Medical History;Medicare;Metabolic syndrome;Metaplasia;Modality;mortality risk;Natural History;Patients;Population;prognostic;Prognostic Marker;Publications;Publishing;Reflux;Research;Research Personnel;Resources;Risk;Risk Factors;Squamous Cell;Staging;Survival Rate;Testing;Tissues;Triage;United States

PROJECT_TITLE: Barrett's Esophagus


NIH_SPENDING_CATS: Biomedical Imaging;Brain Cancer;Brain Disorders;Cancer;Childhood Leukemia;Hematology;Neurosciences;Patient Safety;Pediatric;Pediatric Cancer;Prevention;Radiation Oncology;Rare Diseases

PROJECT_TERMS: Adult;Age;Benefits and Risks;Benign;BRAF gene;Brain;Brain Neoplasms;cancer risk;Case/Control Studies;Child;Childhood;Childhood Leukemia;clinical diagnostics;cohort;Cohort Studies;computed tomography screening;Data;Databases;Dose;Epidemiology;Etiology;Exposure to;Gender;Histopathology;Hospitals;improved;in utero;Incidence;Individual;infancy;International;Intervention;Investigation;Ionizing radiation;KRAS2 gene;leukemia;Life;Lymphoma;Malignant - descriptor;Malignant Childhood Neoplasm;Malignant neoplasm of thyroid;Malignant Neoplasms;Methods;Molecular;molecular marker;NRAS gene;Organ;Papillary Carcinoma;Patients;Physicians;Population Study;Predisposition;Procedures;Publications;Publishing;Radiation;Radiation Dose Unit;radiation effect;Radiation exposure;radiation risk;Radiation-Induced Cancer;RAS genes;Research Personnel;response;Risk;Roentgen Rays;Scientist;Statistical Models;Techniques;Technology;thyroid neoplasm;Time;Tissues;tool;Tumor Tissue;United States;X-Ray Computed Tomography

PROJECT_TITLE: Studies of Populations Exposed to Diagnostic Medical Radiation


NIH_SPENDING_CATS: Cancer;Cancer Genomics;Digestive Diseases;Esophageal Cancer;Genetics;Human Genome;Prevention;Rare Diseases;Stomach Cancer

PI_NAMEs: GOLDSTEIN, ALISA  (contact)

PROJECT_TERMS: Area;Biological Specimen Banks;biomarker identification;Blood;Blood specimen;cancer biomarkers;cancer genetics;Cancer-Predisposing Gene;candidate marker;Case/Control Studies;Cells;County;density;Disease;DNA;esophageal cancer prevention;Etiology;exome sequencing;Family;Family Study;Fingers;gene environment interaction;Genetic;Genetic Markers;Genetic Polymorphism;Genome Scan;genome wide association study;genomic biomarker;Goals;high risk population;Hot Spot;Lesion by Morphology;Malignant neoplasm of esophagus;Malignant Neoplasms;malignant stomach neoplasm;microbiome research;Microsatellite Repeats;Molecular;Morphology;Normal Range;Population;premalignant;Risk;Role;Sampling;Specimen;stomach cardia;Testing;tumor;Venous

PROJECT_TITLE: Esophageal cancer genetic project


NIH_SPENDING_CATS: Cancer;Digestive Diseases;Precision Medicine;Prevention;Rare Diseases

PROJECT_TERMS: Barrett Esophagus;Biological Markers;Biopsy;Biopsy Specimen;Blood;Blood specimen;blood-based biomarker;Clinic;comparison group;Data;Data Analyses;Disease;DNA Sequence Alteration;Dysplasia;Early Diagnosis;Endoscopes;Endoscopy;Esophagus;follow-up;Gastroesophageal reflux disease;Genetic Polymorphism;Genetic Transcription;genotyped patients;Germ Lines;Goals;Hormones;Laboratories;Medical center;patient registry;Patient Selection;Patients;Pattern;Periodicals;Pharmaceutical Preparations;Pilot Projects;Proteomics;Questionnaires;Registries;Risk Factors;Sampling;screening;Serum;stomach cardia;Study of serum;Testing;Time;tissue biomarkers;Tissue Sample;Tissues

PROJECT_TITLE: Barrett's esophagus early detection project


PI_NAMEs: CHANOCK, STEPHEN J. (contact)

PROJECT_TERMS: Affect;Age;Bioinformatics;Biological;Biology;cancer genomics;cancer heterogeneity;cancer risk;cancer subtypes;Cell Line;Chromosome Fragility;Clinical Research;cohort;Collaborations;Consult;Data;Data Pooling;Data Set;deep sequencing;design;Disease;Disease susceptibility;Division of Cancer Epidemiology and Genetics;Elements;Epidemiologist;Epidemiology;epidemiology study;Epigenetic Process;Etiology;Event;Family;follow-up;gene environment interaction;Gene Mutation;Genes;Genetic;genetic analysis;genetic architecture;genetic epidemiology;Genetic Polymorphism;Genetic Predisposition to Disease;Genetic study;genetic variant;Genome;genome wide association study;genome-wide;Genomics;Genotype-Tissue Expression Project;Germ Lines;Haplotypes;Health;high risk;Human;Human Genome;Individual;Inherited;insight;interdisciplinary approach;Interdisciplinary Study;International;Investigation;Laboratories;Laboratory Research;large scale data;Maintenance;Malignant Neoplasms;Methodological Studies;methylation pattern;MicroRNAs;Modeling;Molecular;Molecular Epidemiology;Molecular Evolution;mosaic;Mosaicism;Mutation;Normal tissue morphology;novel;Outcome;Pathway interactions;Phenotype;Population Genetics;Population Study;Populations at Risk;Predictive Value;Predisposition;public database;Regulatory Element;Research;Research Personnel;Resources;Risk;Risk Factors;Scientist;Series;Signal Transduction;Single Nucleotide Polymorphism;Site;Somatic Mutation;Susceptibility Gene;The Cancer Genome Atlas;Therapeutic Intervention;Time;Transcript;tumor;Tumor Tissue;Uniparental Disomy;validation studies;Variant

PROJECT_TITLE: Laboratory of Genetic Susceptibility


NIH_SPENDING_CATS: Biotechnology;Cancer;Cancer Genomics;Cervical Cancer;Genetics;Human Genome;Infectious Diseases;Prevention;Sexually Transmitted Infections;Women's Health Research

PI_NAMEs: MIRABELLO, LISA  (contact)

PROJECT_TERMS: Anti-viral Agents;Base Pairing;Behavior;Biochemical;Biological;cancer risk;carcinogenesis;carcinogenicity;Carcinogens;Case/Control Studies;Cervical;cervical carcinogenesis;Cervical Intraepithelial Neoplasia;Cohort Studies;Disease;Division of Cancer Epidemiology and Genetics;Genetic;Genetic Variation;Genome;genome sequencing;Genomics;Genotype;HIV;Human;Human papilloma virus infection;Human Papilloma Virus-Related Malignant Neoplasm;Human Papillomavirus;Human papillomavirus 16;Infection;Invaded;Learning;Link;Malignant neoplasm of cervix uteri;Malignant Neoplasms;Natural History;next generation sequencing;Nucleotides;Pathogenesis;premalignant;progression risk;Risk;Satellite Viruses;Technology;translational goal;Variant;Viral;virtual;virus genetics;whole genome

PROJECT_TITLE: Human Papillomavirus (HPV) Genomics Project


NIH_SPENDING_CATS: Bioengineering;Biotechnology;Cancer;Clinical Research;Health Services;Machine Learning and Artificial Intelligence;Prevention

PI_NAMEs: WENTZENSEN, NICOLAS  (contact)

PROJECT_TERMS: Artificial Intelligence;assay development;Biological Markers;cancer prevention;cancer risk;carcinogenesis;Clinical;clinical epidemiology;Early Diagnosis;Epidemiologic Factors;Etiology;Evaluation;Genetic;Goals;Image;Lesion;Malignant Neoplasms;Methods;Methylation;Molecular;molecular marker;Natural History;novel;population based;Population Study;premalignant;Prevention strategy;Public Health;Public Health Applications Research;Research;research clinical testing;Research Personnel;Risk Marker;Somatic Mutation;Technology;Testing

PROJECT_TITLE: Clinical Epidemiology


NIH_SPENDING_CATS: Cancer;Cervical Cancer;Clinical Research;HPV and/or Cervical Cancer Vaccines;Health Services;Immunization;Infectious Diseases;Prevention;Primary Health Care;Sexually Transmitted Infections;Social Determinants of Health;Vaccine Related;Women's Health Research

PROJECT_TERMS: Acceleration;Address;Area;Biological Assay;Cancer Control;carcinogenesis;cervical cancer prevention;Cervical Cancer Screening;cost effectiveness;effectiveness validation;Face;Goals;Guidelines;HPV vaccine acceptance;Human Papilloma Virus Vaccine;Human Papillomavirus;Immunization Programs;improved;International;invention;Malignant neoplasm of cervix uteri;Methods;novel;overtreatment;Prevention;Recommendation;Research Personnel;Resource-limited setting;Resources;screening;screening program;Testing;Triage;Vaccination;Visit

PROJECT_TITLE: Cervical Cancer Moonshot


NIH_SPENDING_CATS: Cancer;Cancer Genomics;Clinical Research;Genetics;Human Genome;Prevention

PI_NAMEs: LANDI, MARIA  (contact)

PROJECT_TERMS: Cancer Etiology;Data;Environmental Epidemiology;Epidemiology;genetic epidemiology;Genomics;Germ Lines;Histologic;Malignant Neoplasms;Methods;Mission;molecular pathology;Molecular Profiling;Research;Risk Factors;tumor;tumor progression

PROJECT_TITLE: Studies of Genetic and Environmental Epidemiology


NIH_SPENDING_CATS: Biodefense and Related Countermeasures;Burden of Illness;Cancer;Clinical Research;Coronaviruses;Coronaviruses Disparities and At-Risk Populations;Emerging Infectious Diseases;Genetics;Infectious Diseases;Lung;Prevention

PI_NAMEs: SAVAGE, SHARON A. (contact)

PROJECT_TERMS: 2019-nCoV;Acute;Acute respiratory infection;Authorization documentation;Biological Markers;Cessation of life;China;Clinical;Communicable Diseases;Communities;comorbidity;COVID-19;COVID-19 impact;COVID-19 monitoring;COVID-19 pandemic;COVID-19 risk;COVID-19 susceptibility;Data;data sharing;Death Rate;Deposition;Descriptive Epidemiology;Disease;Division of Cancer Epidemiology and Genetics;effective therapy;Epidemiology;epidemiology study;Genetic Predisposition to Disease;genetic variant;Germ Lines;Individual;Infection;Life;Malignant Neoplasms;multidisciplinary;Multiple Organ Failure;Outcome;pandemic disease;Pneumonia;Population;Prevention Measures;Public Health;reduce symptoms;Research Personnel;respiratory;Respiratory Failure;Risk;SARS-CoV-2 infection;Scientist;severe COVID-19;Symptoms;Syndrome;Testing;United States;United States National Institutes of Health

PROJECT_TITLE: Epidemiology and Genetics of Susceptibility to COVID-19 Infection


NIH_SPENDING_CATS: Cancer;Clinical Research;Emerging Infectious Diseases;HIV/AIDS;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Infectious Diseases;Prevention

PROJECT_TERMS: Acquired Immunodeficiency Syndrome;Aging;antiretroviral therapy;Behavior;biomarker identification;burden of chronic illness;cancer biomarkers;cancer diagnosis;cancer prevention;cancer therapy;Chronic;Disease;Disparity;Etiology;General Population;Health Services Accessibility;Hepatitis B Virus;Herpesviridae;HIV;HIV Infections;Human Herpesvirus 4;Human Herpesvirus 8;Human Papillomavirus;immunosuppressed;Immunosuppression;improved;Incidence;Individual;Infection;Inflammation;Intervention;Malignant Neoplasms;Natural History;Oncogenic Viruses;Outcome;Persons;prevent;risk stratification;Role;screening;Socioeconomic Status;Tobacco smoking behavior;Virus

PROJECT_TITLE: Studies of HIV infection and its contribution to the natural history and outcome


NIH_SPENDING_CATS: Cancer;Genetics

PI_NAMEs: MACHIELA, MITCHELL  (contact)

PROJECT_TERMS: Alleles;Data;design;Disease susceptibility;flexibility;Genetic Structures;Haplotypes;interactive visualization;interest;Libraries;Link;Linkage Disequilibrium;Maps;Measures;Multiomic Data;open source;Pattern;Population;Population Group;Regional Disease;Research Personnel;Susceptibility Gene;tool;Variant;web app;web-based tool

PROJECT_TITLE: LDlink webtool for examining patterns of linkage disequilibrium in diverse popul


NIH_SPENDING_CATS: Cancer;Cervical Cancer;Clinical Research;Dental, Oral, and Craniofacial Disease;HIV/AIDS;HPV and/or Cervical Cancer Vaccines;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Immunization;Infectious Diseases;Prevention;Sexually Transmitted Infections;Vaccine Related;Women's Health Research

PI_NAMEs: CASTLE, PHILIP  (contact)

PROJECT_TERMS: Adult women;Africa South of the Sahara;Anogenital cancer;Antibodies;Anus;Biological Assay;Blood;Cancer Control;Cancer Intervention;cervicovaginal;Country;Development;Dose;Effectiveness;Enrollment;Etiology;Evaluation;Focus Groups;Future;Gardasil;Genotype;Goals;Health;High Risk Woman;HIV;HIV Seronegativity;HIV Seropositivity;Human;Human Papilloma Virus Vaccination;Immune;Immunity;Immunization Programs;low and middle-income countries;malignant mouth neoplasm;Malignant neoplasm of cervix uteri;Malignant Neoplasms;Mass in breast;Natural History;new technology;novel strategies;Observational Study;Oral;Palpable;Participant;Population;Prevalence;prevent;Prevention;programs;prophylactic;Questionnaires;Recording of previous events;Research;Research Project Grants;Risk Factors;risk prediction;Rwanda;screening;Sexual Health;Specimen;symptom science;Testing;Underserved Population;unvaccinated;Upper aerodigestive tract cancer;Vaccinated;Vaccination;Vaccines;vaginal microbiome;Validation;Virus;Woman;Women's cohort;Women's Group;Women's study

PROJECT_TITLE: Global Cancer Health


NIH_SPENDING_CATS: Cancer;Cervical Cancer;HIV/AIDS;Infectious Diseases;Prevention;Sexually Transmitted Infections;Women's Health Research

PROJECT_TERMS: Acquired Immunodeficiency Syndrome;Anus;Biological Markers;burden of illness;California;carcinogenesis;Cervical;cervical cancer prevention;Cervix Uteri;cohort;Collaborations;Data;data resource;Disease;Division of Cancer Epidemiology and Genetics;Epithelium;Evaluation;Genotype;Health;HIV;HIV Seropositivity;HIV/AIDS;Human papilloma virus infection;Human Papilloma Virus-Related Malignant Neoplasm;Human Papillomavirus;Louisiana;Maintenance;Malignant Neoplasms;Medical Genetics;men;men who have sex with men;Michigan;Molecular;neoplasm registry;Outcome Study;Persons;Population;population based;premalignant;Prevalence;programs;Puerto Rico;Research;Research Personnel;screening;Screening for cancer;tissue resource;Tissues;Update;Vagina;Vulva;Woman;Work

PROJECT_TITLE: HPV related cancers in HIV populations


NIH_SPENDING_CATS: Behavioral and Social Science;Cancer;Clinical Research;Genetics;Infectious Diseases;Lung;Lung Cancer;Prevention;Women's Health Research

PI_NAMEs: JACKSON, SARAH  (contact)

PROJECT_TERMS: Alcohol consumption;Behavior;Biological;Biology;cancer risk;cancer survival;carcinogenicity;cell growth;Diet;Epigenetic Process;Estrogens;Female;Gene Expression;Genetic;Goals;Gonadal Steroid Hormones;health seeking behavior;Hepatitis B Virus;Hepatitis C virus;high risk;High Risk Woman;Human Herpesvirus 4;Human Papillomavirus;Immune response;Immunity;Incidence;Infection;infection related cancer;infection risk;Intrinsic factor;male;Malignant Neoplasms;men;Oncogenic;Physical activity;Predisposition;Progesterone;programs;Research;Risk;Risk Adjustment;Risk Factors;Risk Taking;sex;Sex Differences;Site;Smoking;Testosterone;Tumor Escape;Tumor Suppressor Genes;Variant;Woman;X Inactivation

PROJECT_TITLE: Biology of sex and cancer


NIH_SPENDING_CATS: Behavioral and Social Science;Cancer;Clinical Research;Clinical Trials and Supportive Activities;Digestive Diseases;HIV/AIDS;Infectious Diseases;Prevention;Sexually Transmitted Infections

PI_NAMEs: CLARKE, MEGAN  (contact)

PROJECT_TERMS: Anogenital cancer;Anus;Attitude;Biological Markers;biomarker performance;California;Caring;Cervical Cancer Screening;Clinic;Collection;Data;Detection;Enrollment;Evaluation;experience;General Population;Goals;high risk;HIV;Human Papillomavirus;Incidence;Individual;Infrastructure;Malignant neoplasm of anus;Malignant Neoplasms;medical specialties;men who have sex with men;Nevada;Participant;Persons;Population;premalignant;prevent;Provider;randomized trial;Sampling;screening;Screening for cancer;screening program;Specimen;Testing

PROJECT_TITLE: Evaluation of anal self-sampling in HIV men-who-have-sex-with-men (HIV MSM) populations


NIH_SPENDING_CATS: Cancer;Cervical Cancer;Clinical Research;Clinical Trials and Supportive Activities;Dental, Oral, and Craniofacial Disease;Digestive Diseases;HIV/AIDS;Infectious Diseases;Prevention;Rare Diseases;Sexually Transmitted Infections;Women's Health Research

PI_NAMEs: KREIMER, AIMEE  (contact)

PROJECT_TERMS: Age;age stratification;Anogenital cancer;anti-cancer research;Anus;Archives;Biological Markers;Cancerous;Cervical;Cervical Cancer Screening;Cervix Carcinoma;Data Linkages;data registry;Diagnosis;Etiology;Evaluation;Genitalia;Genotype;German population;Goals;HIV;HIV Infections;Hospitals;HPV screening;Human Papilloma Virus Vaccination;Human Papilloma Virus-Related Malignant Neoplasm;Human Papillomavirus;improved;Individual;insight;Laboratories;Malignant Neoplasms;malignant oropharynx neoplasm;Oncogenic;Oncology;Oropharyngeal;Pathology;penis;Persons;Population Attributable Risks;Prevention strategy;Race;Sampling;sex;Site;South Africa;South African;Squamous cell carcinoma;Tissues;tumor;Vagina;Viral;Vulvar Squamous Cell Carcinoma;Work

PROJECT_TITLE: Evaluating Differences in HPV Attributable Fraction and Genotype Distribution in Cervical, Anal, Genital, and Oropharyngeal Cancers among People with and without HIV infection in South Africa


ADMINISTERING_IC: DC

IC_NAME: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

PI_NAMEs: WU, DORIS  (contact)

PROJECT_TERMS: Acceleration;Address;Afferent Neurons;Age;Alleles;Apical;Area;Auditory;Behavioral;behavioral phenotyping;Bipolar Neuron;Brain;Candidate Disease Gene;Cell Cycle;Clinical;Collaborations;Complex;conditional knockout;Crista ampullaris;Databases;deafness;Defect;Deoxyuridine;design;Development;DNA;Dorsal;Ear;Early identification;emx2 protein;Enzymes;Equilibrium;erection;Etiology;Evoked Potentials;Exhibits;Future;Generations;Genes;Genetic;Goals;Hair;Hair Cells;Head;Head Movements;hearing impairment;Human;Individual;inner ear development;Intervention;Labyrinth;Location;macula;malformation;mechanotransduction;Mitosis;Modeling;Molecular;Morphogenesis;Morphology;Movement;Mus;mutant;Mutant Strains Mice;neuroblast;neuronal cell body;Neurons;Organ;otoconia;Patients;Peripheral;Phenotype;Positioning Attribute;Production;Publishing;Reporting;Reproducibility;response;S phase;Saccule and Utricle;segregation;Sensory;Sensory Hair;sensory system;Shapes;Signal Transduction;single-cell RNA sequencing;sound;Structure;Surface;Swimming;Testing;Time;Tissues;Tremor;Tretinoin;Universities;Vestibular dysfunction;Vestibular ganglion;Vestibular inner ear;vestibular system

PROJECT_TITLE: Molecular Basis For The Morphogenesis Of The Inner Ear


NIH_SPENDING_CATS: Hearing Loss;Neurosciences

ORG_NAME: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

PI_NAMEs: KINDT, KATIE  (contact)

PROJECT_TERMS: Affect;Afferent Neurons;Age;Anatomy;Animal Model;Auditory;Behavior;Biological Models;Brain;cell injury;Cell Physiology;Cells;Clinical Treatment;Collection;CRISPR/Cas technology;Data;Defect;density;Development;Ensure;Equilibrium;Event;Fatigue;Functional Imaging;Genes;Genetic;Goals;hair cell regeneration;Hair Cells;Hearing;hearing impairment;Image;imaging approach;Impairment;in vivo;Investigation;Kinesin;Knowledge;Label;lateral line;Light;Link;Mediating;Microscope;Microscopy;Microtubules;Modeling;Molecular;Morphology;Motor;Mus;mutant;Natural regeneration;neuromast;Neurons;Noise-Induced Hearing Loss;Pathology;postsynaptic;Preparation;Presbycusis;presynaptic;Process;Proteins;Publishing;recruit;repaired;Research;Research Project Grants;research study;Resolution;response;restoration;ribbon synapse;Role;Sensory;Sensory Hair;sensory system;Series;Structure;Summary Reports;Synapses;synaptic function;Synaptic Vesicles;synaptogenesis;System;Systems Development;Time;Transgenic Organisms;transmission process;vesicle transport;vesicular release;vestibular system;Visualization;water flow;Work;Zebrafish

PROJECT_TITLE: In vivo investigation of sensory hair cell function and development


NIH_SPENDING_CATS: Biotechnology;Brain Disorders;Clinical Research;Hearing Loss;Machine Learning and Artificial Intelligence;Neurosciences

PI_NAMEs: HOA, MICHAEL  (contact)

PROJECT_TERMS: Adult;Auditory;Autoimmune;Autoimmune Inner Ear disease;autoinflammatory;automated segmentation;Bacterial Artificial Chromosomes;Basal Cell;cell type;Cells;Clinical Data;Clinical Protocols;Cochlea;Cochlear duct;Collaborations;Communities;contrast enhanced;cytokine;Data Set;deep learning;Deposition;Development;Disease;druggable target;effective therapy;Endolymph;Endolymphatic Hydrops;Etiology;experience;Flow Cytometry;Gene Expression Profile;gene regulatory network;Generations;Genetic Transcription;Goals;Hair Cells;Head and neck structure;healthy volunteer;Hearing;hearing restoration;Hearing Tests;Heterogeneity;Homeostasis;Human;human disease;Image;Image Analysis;Immunophenotyping;inner ear diseases;Investigation;Ions;Laboratories;Labyrinth;Lateral;Location;machine learning method;Macrophage;Magnetic Resonance Imaging;Manuscripts;Masks;Measures;mechanotransduction;Meniere's Disease;Molecular;mouse model;Mus;new therapeutic target;novel;novel therapeutics;Otology;Paper;Pathway interactions;patient subsets;Patients;Pericytes;phenomics;Phenotype;Play;Preparation;Process;programs;progressive hearing loss;Proteomics;Publications;Publishing;recruit;Regulation;Reporter;Reporting;Research;response;restoration;Role;Sensorineural Hearing Loss;single nucleus RNA-sequencing;Steroids;Stria Vascularis;Symptoms;Syndrome;Temporal bone structure;Therapeutic;therapeutic target;tool;Transgenic Mice;treatment trial;Vestibular Aqueduct;Work

PROJECT_TITLE: Cellular and Molecular Pathways for Hearing Restoration in the Adult Inner Ear


NIH_SPENDING_CATS: Aging;Biotechnology;Data Science;Estrogen;Genetics;Hearing Loss;Human Genome;Neurodegenerative;Neurosciences;Prevention;Women's Health Research

PI_NAMEs: HERTZANO, RONNA  (contact)

PROJECT_TERMS: Acquired Deafness;Adopted;Advanced Development;Affect;Age;age effect;Animals;Area;Auditory;Biology;cell type;Cells;Clinical Data;Clinical Research;Collaborations;college;Comprehension;congenital hearing loss;Critical Pathways;Data;Data Set;data sharing;Dedications;design;Development;Disabling;Disease;Educational workshop;equilibration disorder;Equilibrium;Estrogens;experience;FDA approved;Feedback;Female;functional genomics;fundamental research;Gender;Gene Expression Profiling;Gene Expression Regulation;gene regulatory network;Genes;Genetic;genomic data;Goals;Hair Cells;Health;Hearing;hearing impairment;hearing preservation;Hearing problem;hearing restoration;hereditary hearing loss;Human;Image;improved;In Vitro;in vivo Model;Incidence;Individual;inner ear development;inner ear injury;innovation;insight;interdisciplinary approach;Investigation;Laboratories;Labyrinth;Light;Maintenance;male;Maryland;Mediator;medical schools;meetings;Mesenchyme;Metformin;Molecular;molecular marker;Multiomic Data;multiple omics;Mus;Mutation;National Institute on Deafness and Other Communication Disorders;Newborn Infant;next generation;Noise;noise exposure;Noise-Induced Hearing Loss;novel;novel therapeutics;Otolaryngology;otoprotectant;Outcome;Outer Hair Cells;Pathogenesis;Pathway interactions;Physiological;Physiology;Population;practical application;Pre-Clinical Model;Predisposition;Presbycusis;prevent;Prevention;programs;Protocols documentation;Publishing;Raloxifene;Research;Resources;Role;Scientist;Selective Estrogen Receptor Modulators;Sex Differences;Signal Pathway;Stria Vascularis;Techniques;Therapeutic;Therapeutic Intervention;tool;transcription factor;transcriptomics;Translational Research;translational study;Universities;Update;Vestibular Hair Cells;vestibular system;Visualization;Work

PROJECT_TITLE: Multi-Omic and Functional Analyses for Hearing Preservation and Restoration


NIH_SPENDING_CATS: Genetics;Hearing Loss;Neurosciences

PI_NAMEs: BALLESTEROS, ANGELA  (contact)

PROJECT_TERMS: Affect;Affinity;Aging;Apical;Apoptotic;Auditory;auditory neuropathy;Axon;Bacteria;Binding Sites;Biochemical;Biophysics;Caspase;cell injury;Cell Maintenance;Cell membrane;Cell Physiology;Cell Survival;cell type;Cells;Cellular biology;Complex;CRISPR/Cas technology;Data;deafness;Development;Diagnostic;Disease;Epitopes;equilibration disorder;Equilibrium;Exhibits;Family;Functional disorder;Future;G-Protein-Coupled Receptors;Generations;Genes;genetic regulatory protein;Goals;grasp;Hair Cells;Head Movements;Health;Hearing;hearing impairment;Hearing problem;Homeostasis;Human;Immunoprecipitation;improved outcome;In Vitro;in vivo;Individual;Inherited;innovation;insight;Integrins;interdisciplinary approach;Investigation;Ion Channel;Kinetics;Knockout Mice;Labyrinth;Link;Lipids;Liposomes;Maintenance;mechanical signal;mechanical stimulus;Mechanics;mechanotransduction;Membrane;Molecular;Molecular Biology;mouse model;Mus;Mutation;neurotransmission;noise exposure;novel;novel therapeutics;Organism;ototoxicity;Pathway interactions;Physiological;Physiology;Play;postnatal development;prevent;Process;Property;Protein Isoforms;Proteins;reconstitution;Research;Research Project Grants;Role;Scientist;Sensory;Sensory Hair;Sensory Physiology;Sensory Process;sound;Specificity;Structure;Summary Reports;System;Techniques;Therapeutic;Therapeutic Intervention;Time;Variant;Vertebrates;Vestibular function;vibration;Work

PROJECT_TITLE: Sensory Hair Cell Homeostasis


ADMINISTERING_IC: HG

IC_NAME: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

NIH_SPENDING_CATS: Cancer;Dental, Oral, and Craniofacial Disease;Genetics;Hematology;Human Genome;Pediatric;Pediatric Cancer;Prevention;Primary Immunodeficiencies;Rare Diseases

PI_NAMEs: CHANDRASEKHARAPPA, SETTARA  (contact)

PROJECT_TERMS: acetaldehyde dehydrogenase;Acute Myelocytic Leukemia;Affect;Age;Age of Onset;Alcohols;aldehyde dehydrogenases;Aldehydes;Anemia;Aplastic Anemia;Appearance;Asian population;attenuation;autosome;Biological Markers;Bone marrow failure;bone marrow failure syndrome;Breast Cancer Risk Factor;cancer predisposition;Candidate Disease Gene;Carbon;Case Study;Clinical;Clinical Management;Clinical Treatment;cohort;Complement;Complementary DNA;Congenital Abnormality;Custom;de novo mutation;Defect;deletion detection;density;design;Development;Diagnosis;Disease;disease-causing mutation;DNA;DNA Crosslinking Agent;DNA Sequence Alteration;Dysmyelopoietic Syndromes;Early Diagnosis;Enzymes;Evaluation;Family;Family member;FANCB;Fanconi Anemia Complementation Group A Protein;Fanconi Anemia pathway;Fanconi's Anemia;founder mutation;Gene Mutation;gene panel;Gene Targeting;Generations;Genes;Genetic Variation;genomic signature;Genomics;Genotype;Goals;Head and Neck Squamous Cell Carcinoma;Hematology;Hematopoietic;Heterozygote;improved;Individual;Inherited;Inherited bone marrow failure;insertion/deletion mutation;Knock-out;knockout gene;Length;Life;Link;Malignant neoplasm of ovary;Malignant neoplasm of pancreas;Malignant Neoplasms;Manuscripts;Measurement;Messenger RNA;Metabolism;Methodology;Mitotic Recombination;Modeling;Molecular;Molecular Diagnosis;molecular subtypes;mosaic;Mosaicism;mouth squamous cell carcinoma;mutant;Mutation;Nature;Oral cavity;Pancytopenia;Pathogenicity;Patients;Phenotype;Population;Predisposition;Process;prophylactic;Proteins;Protocols documentation;Publishing;Rare Diseases;Reporting;Risk;RNA;RNA Splicing;Screening for Oral Cancer;Screening procedure;Site;SNP array;Solid Neoplasm;Somatic Mutation;South Asian;Techniques;Technology;Thrombosis;Tissues;TP53 gene;Transcript;transcriptome sequencing;Transgenic Organisms;United States National Institutes of Health;Universities;Variant;Zebrafish


NIH_SPENDING_CATS: Congenital Structural Anomalies;Dietary Supplements;Genetics;Human Genome;Neurosciences;Nutrition;Pediatric;Prevention;Rare Diseases;Spina Bifida

ORG_NAME: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

PI_NAMEs: BRODY, LAWRENCE C (contact)

PROJECT_TERMS: Affect;Affinity;Age;Anemia;Animal Model;Animals;anxious behavior;Binding;Bioinformatics;Biological;Biological Assay;Biological Availability;Biology;Blood;Brain;Carbon;Caring;Carrier Proteins;Cell division;cell growth;Cells;cellular targeting;Choline;circulating biomarkers;Circulation;Clinical;Code;Cohort Studies;Collaborations;college;Congenital Abnormality;cost;Data;Defect;Deposition;Development;Diet;dietary;Disease;DNA;DNA Methylation;Embryo;Environment;Environmental Exposure;Environmental Risk Factor;Equilibrium;Exhibits;experimental study;Female;fetus nutrition;Fishes;Folic Acid;Folic Acid Deficiency;Formates;Frequencies;Funding;Future;Gene Expression;Genes;Genetic;Genetic Predisposition to Disease;Genetic Research;genetic variant;Genetic Variation;genome wide association study;Genotype;genotyping technology;Glycine;Goals;Hair Color;Health;Heart Diseases;heteroplasmy;Homocysteine;Human;Human Genome;Impaired cognition;implantation;improved;Individual;Infertility;Inherited;Injections;Inositol;insight;International;Knock-out;Length;Literature;Liver;Location;Malignant Neoplasms;Measures;melanocyte;Metabolic;Metabolic Pathway;Metabolism;Methionine;Methods;Methylmalonic Acid;Micronutrients;Mitochondria;Mitochondrial DNA;Modeling;mouse model;Mus;Nervous System Physiology;Neural Tube Defects;Neurologic;Normal Range;Nutrient;offspring;Other Genetics;Ovulation;Pathway interactions;Population;Pregnancy;Process;Proteins;Publishing;recruit;Reporting;Research;research clinical testing;Research Personnel;Retina;Risk;Role;Sample Size;Sampling;Side;Spinal Dysraphism;System;Testing;Tissues;Transcobalamins;tumor;uptake;Variant;Vitamin B 12;Vitamin B 12 Deficiency;Vitamin B6;vitamin receptor;whole genome;Work;Zebrafish

PROJECT_TITLE: The contribution folate and vitamin B12 genes to disease.


NIH_SPENDING_CATS: Attention Deficit Hyperactivity Disorder (ADHD);Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Clinical Research;Genetics;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Human Genome;Mental Health;Mental Illness;Neurosciences;Pediatric;Social Determinants of Health;Substance Misuse

PI_NAMEs: SHAW, WALLACE PHILIP (contact)

PROJECT_TERMS: 11q;11q22;addiction;Adhesions;Adolescent;Adult;Affect;Alcohols;alpha-latrotoxin receptor;ANKK1 gene;Attention deficit hyperactivity disorder;axon guidance;base;Behavior;Behavior Disorders;Binding Sites;Brain;Brain region;Brazil;Canada;cell motility;Child;Chromosomes;cohort;Colombia;comorbidity;Conduct Disorder;Confidence Intervals;Conserved Sequence;Data;Development;Diagnosis;Disease;disease natural history;Disparate;DRD2 gene;Drug Modulation;drug seeking behavior;Drug user;economic implication;Educational Status;Embryonic Development;endophenotype;Enhancers;Epidemiology;Family;FLRT3 gene;Functional disorder;G-Protein-Coupled Receptors;Genes;Genetic;genetic analysis;Genetic Epistasis;Genetic Predisposition to Disease;Genetic Transcription;genetic variant;genome-wide;genome-wide linkage;Genomic Segment;Genotype;Germany;Goals;Haplotypes;Health;Illicit Drugs;Impairment;Incidence;Individual;Investigation;Knock-out;Legal;Ligands;Link;Low income;Maintenance;Manuscripts;Maps;Measures;member;Membrane Proteins;Metabolism;Modeling;Mus;Myelin;myelination;NCAM1 gene;neurodevelopment;Neurons;Neuropsychology;noradrenergic;Norway;Oppositional Defiant Disorder;Paper;Patients;Penetrance;personalized medicine;Persons;Pharmaceutical Preparations;Play;Population Attributable Risks;Postsynaptic Membrane;predicting response;Predisposition;Prevalence;Public Health;Publishing;Reporting;Research;Risk;risk variant;Role;segregation;Severities;Shapes;social relationships;socioeconomic disadvantage;socioeconomics;South Korea;Spain;Sphingolipids;Stimulant;Substance Use Disorder;Surface;Susceptibility Gene;Symptoms;System;Therapeutic;tobacco user;transcription factor;Twin Multiple Birth;Underemployment;Untranslated RNA;Variant;Work;World Health Organization;YY1 Transcription Factor;Zebrafish

PROJECT_TITLE: Genetic Analysis of Attention Deficit Hyperactivity Disorder


NIH_SPENDING_CATS: Autism;Biotechnology;Brain Disorders;Childhood Obesity;Clinical Research;Gene Therapy;Genetics;Human Genome;Intellectual and Developmental Disabilities (IDD);Kidney Disease;Mental Health;Nutrition;Obesity;Orphan Drug;Osteoporosis;Pediatric;Precision Medicine;Prevention;Rare Diseases

PI_NAMEs: VENDITTI, CHARLES P (contact)

PROJECT_TERMS: Acyl Coenzyme A;Adipose tissue;Affect;amino acid metabolism;Animal Model;Area;Australia;autism spectrum disorder;Basal Ganglia;Bezafibrate;Biochemistry;Biological Markers;Blindness;Branched-Chain Amino Acids;Brown Fat;Cardiac;Cardiomyopathies;Categories;Central obesity;Child;Chronic;Chronic Kidney Failure;circulating biomarkers;Clinic;Clinical;clinical care;clinical center;Clinical Protocols;Clinical Research;Clinical Trials Design;Cobalamin;cohort;Collaborations;Communities;Complex;Data;Databases;Dedications;Developed Countries;Development;Developmental Delay Disorders;Diabetes Mellitus;Diagnosis;Disease;disease model;Disease Progression;Drug or chemical Tissue Distribution;Early Intervention;Effectiveness;End stage renal failure;Exhibits;Extrahepatic;Face;Fatty acid glycerol esters;fibroblast growth factor 21;Frequencies;Functional disorder;gene therapy;Gene therapy trial;Genes;Genetic;genetic approach;genome editing;Genomic approach;Genomic medicine;Genomics;Goals;Government;Growth;hearing impairment;Heart failure;HIV-Associated Lipodystrophy Syndrome;human subject;Immunosuppression;Impairment;improved;Inborn Errors of Metabolism;Infant;Inherited;insight;Intellectual functioning disability;Intervention Trial;Investigation;ketotic hyperglycinemia;Kidney;Knock-out;Laboratories;Legal patent;Link;Lipodystrophy;Lipomatosis;Liver;Liver diseases;long-term sequelae;Medical;Messenger RNA;Metabolic;Metabolic Diseases;Metabolism;metabolomics;methylmalonic aciduria;methylmalonyl coA mutase deficiency;Methylmalonyl-CoA Mutase;microbiome;Mitochondria;mitochondrial dysfunction;Modeling;Morbidity - disease rate;mouse model;Myocardial dysfunction;National Center for Advancing Translational Sciences;National Heart, Lung, and Blood Institute;National Institute of Mental Health;Natural History;Neonatal Screening;Neurologic;Newborn Infant;novel;novel therapeutics;NPC1 gene;Obesity;optimal treatments;organ transplant rejection;Organ Transplantation;Osteoporosis;Outcome;Pancreas;Pancreatitis;Pathology;Pathway interactions;Patients;Pattern;Phenotype;Physiology;Plasma;Post-Translational Protein Processing;potential biomarker;Prognosis;programs;propionyl-coenzyme A;Proteomics;Publishing;Reporting;research study;Risk;screening;Severity of illness;small molecule;Stroke;Study Section;subcutaneous;Symptoms;Syndrome;targeted treatment;Testing;Therapeutic Intervention;Thermogenesis;Transgenic Mice;translational research program;Transplantation;treatment effect;Treatment Protocols;United States National Institutes of Health;vector;Visceral fat;Visual impairment;Vitamin B 12;Vitamin B 12 Deficiency;Zebrafish

PROJECT_TITLE: Investigations of Methylmalonic Acidemia and Related Disorders


NIH_SPENDING_CATS: Clinical Research;Genetics;Human Genome;Precision Medicine;Primary Health Care

PI_NAMEs: BONHAM, VENCE L (contact)

PROJECT_TERMS: Address;Algorithms;Anxiety;Attitude;Belief;Biological;Caring;Characteristics;Clinical;clinical care;clinical decision-making;clinical practice;Data;Decision Making;Development;Discipline of Nursing;Disease;Dose;Educational Status;Empirical Research;Ethnic Origin;experimental study;Factor Analysis;Family Practice;Future;Genetic;Genetic Predisposition to Disease;Genetic Risk;genetic testing;Genetic Variation;Genomic medicine;Genomics;Genotype;Health;health assessment;health disparity;health equity;Health Personnel;Health Professional;Health Services Research;Hospitals;HP gene;Human Genetics;human genome sequencing;implicit bias;Individual;Internal Medicine;Internist;Interview;Journals;Knowledge;Measures;Medical;member;Methods;Modeling;Nurse Practitioners;Nurses;Outcome;Patient Self-Report;Patients;personalized medicine;Pharmaceutical Preparations;Phase;Physicians;Politics;precision medicine;Primary Care Physician;primary care practice;Public Health Practice;Publishing;Qualitative Methods;Qualitative Research;Race;Registered nurse;Regression Analysis;Reporting;Research;research clinical testing;Research Methodology;Research Personnel;Residencies;response;Sampling;Scholarship;Serotonin;Students;Surveys;Test Result;Testing;Training;translational genomics;Uncertainty;United States;virtual;Warfarin

PROJECT_TITLE: Understanding the Relationships between Race, Ethnicity, Ancestry and Genomics


NIH_SPENDING_CATS: Biotechnology;Clinical Research;Congenital Structural Anomalies;Genetics;Human Genome;Orphan Drug;Pediatric;Rare Diseases

PI_NAMEs: BIESECKER, LESLIE  (contact)

PROJECT_TERMS: Affect;Agreement;AKT1 gene;Alleles;Animal Model;Animals;Antineoplastic Agents;Award;Behavioral;Biological Models;Biological Process;Biomechanics;Biotechnology;Cell Culture Techniques;Cells;Clinical;Clinical Data;Clinical Research;Clinical Research Protocols;Clinical Trials;cohort;Collaborations;Cooperative Research and Development Agreement;Coupled;Development;Disease;disease model;Dose;Drug Industry;Embryo;Enrollment;Etiology;Experimental Models;feature detection;Gene Abnormality;gene product;Genes;Genetic Diseases;Genomics;Genotype;Growth;Growth Disorders;High-Throughput Nucleotide Sequencing;Human;Human Genetics;human model;In Vitro;inducible Cre;inhibitor;Knock-in;Laboratories;malformation;Malignant Neoplasms;Mediation;Modeling;Modernization;Molecular;Molecular Biology;Molecular Genetics;mosaic;Mosaicism;mouse model;Mus;Mutation;Natural History;novel;novel therapeutics;Other Genetics;Pathogenesis;Patients;Pharmacotherapy;Phase;phase 2 study;phase II trial;Phenotype;PIK3CA gene;positional cloning;Postdoctoral Fellow;prenatal;prenatal therapy;primary outcome;Proteins;Proteus;Proteus Syndrome;Proto-Oncogene Proteins c-akt;Protocols documentation;Publishing;Rare Diseases;recruit;Research;Sampling;Severities;Shapes;Sirolimus;Stress;success;Syndrome;System;targeted treatment;Testing;Therapeutic;Therapeutic Agents;Therapeutic Intervention;Therapeutic Studies;Time;tissue culture;tool;Translational Research;Treatment Protocols;tumor;Vascular remodeling;Work

PROJECT_TITLE: Rare & Mosaic Disorders Molecular Research


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Clinical Research;Genetics;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Hematology;Human Genome;Prevention;Racial and Ethnic Minority Health Research;Rare Diseases;Sickle Cell Disease;Social Determinants of Health

PI_NAMEs: KOEHLY, LAURA M (contact)

PROJECT_TERMS: Address;Affect;Area;Assessment tool;Behavior;Chronic Disease;Clinic;Collaborations;Communication;Communities;Community Health;Community Health Education;Complex;contextual factors;coping;COVID-19;COVID-19 pandemic;Data;Development;diaries;Disease;disorder risk;Educational process of instructing;Evaluation;experience;Family;Family health status;family influence;Feedback;Female;Florida;follow up assessment;Funding;Genetic Diseases;Goals;health assessment;Health Disparities Research;Helping Behavior;Hereditary Disease;Hispanic;Household;Individual;Inherited;Institutional Review Boards;International;Intervention;Kidney Diseases;Longitudinal Surveys;Malignant Neoplasms;Medical center;Mental Health;Mexican Americans;minority communities;minority health;minority health disparity;National Human Genome Research Institute;National Institute of Drug Abuse;Network-based;Nigeria;Non-Insulin-Dependent Diabetes Mellitus;Participant;Patient Recruitments;Pediatric Hospitals;Pennsylvania;Persons;Phase;Populations at Risk;Process;programs;Protocols documentation;Recording of previous events;recruit;Research;resilience;Risk;Risk Reduction;Rural;Series;Sickle Cell Anemia;social;Social Distance;Social Environment;South Australia;Spanish/English;stressor;Testing;tool;Universities;video module;Washington;Work

PROJECT_TITLE: The influence of familial social context on risk dissemination and coping


NIH_SPENDING_CATS: Cancer;Genetics;Human Genome;Uterine Cancer;Women's Health Research

PI_NAMEs: BELL, DAPHNE  (contact)

PROJECT_TERMS: ACVR1 gene;Affect;American;American Cancer Society;Binding;Biochemical;Biological Markers;Body of uterus;c-myc Genes;Cancer Etiology;cancer genome;Carcinoma;CCNE1 gene;Cell Line;cell type;Cells;Cessation of life;Clinical;clinically relevant;Complex;Cyclin-Dependent Kinase Inhibitor;Data Set;design;Development;Disease;disease-causing mutation;druggable target;Endometrial Carcinoma;Endometrial Neoplasms;Endometrium;Epithelium;Exhibits;experimental study;FBXW7 gene;gain of function;Genes;Genetic;Genome;genomic tools;Genomics;Germ Lines;Goals;Histologic;Human;in silico;Individual;inhibitor;interest;Knock-in;Laboratories;MADH2 gene;Malignant Epithelial Cell;Malignant Neoplasms;Manuscripts;Medicine;meetings;Missense Mutation;Molecular;Molecular Abnormality;Molecular Analysis;Molecular Carcinogenesis;mutant;Mutate;Mutation;mutation correction;Nature;NCOA3 gene;Neural Cell Adhesion Molecule L1;Newly Diagnosed;novel;novel therapeutics;Oncogenic;Outcome;Pathogenicity;Pathology;Pathway interactions;Phosphoproteins;phosphoproteomics;Phosphorylation;Phosphotransferases;predictive modeling;prevent;Prognosis;progressive myositis ossificans;protein function;Protein-Serine-Threonine Kinases;Proteins;Proteomics;Proto-Oncogene Proteins c-akt;Recurrence;Reporting;Research;Series;Serous;Signal Transduction;Somatic Mutation;Structural Models;Tertiary Protein Structure;Testing;TGF-beta type I receptor;TGFBR1 gene;transcription factor;tumor;Tumor Promotion;Tumor Suppressor Proteins;ubiquitin ligase;Ubiquitination;United States;Uterine Corpus Carcinosarcoma;Uterus;Validation;Variant;Woman;Work;Writing

PROJECT_TITLE: Molecular Analyses of Endometrial Cancer


NIH_SPENDING_CATS: Biotechnology;Clinical Research;Genetics;Human Genome;Precision Medicine

PROJECT_TERMS: Address;Affect;Agreement;American;Area;arm;Automation;Bayesian Modeling;Benign;biobank;Biological Assay;Blood specimen;cascade genetic testing;Classification;Clinical;clinical care;Clinical Medicine;clinical practice;Clinical Research;cohort;Collaborations;Communication;cost;Coupling;Data;Data Analyses;Development;Diagnostic;Disease;Environment;Evaluation;Evaluation Studies;exome sequencing;Family;Family member;Foundations;Functional disorder;Future;Genes;Genetic;genetic variant;Genets;Genome;genome sequencing;genome-wide;genomic data;Genomic medicine;genomic predictors;Genomics;Genotype;Goals;Guidelines;Health Care Costs;Health Services Research;Healthcare;Human;Image;improved;Individual;Infrastructure;Intake;Laboratories;Leadership;Malignant hyperpyrexia due to anesthesia;Medical;Medical Genetics;medical schools;Medicine;Modeling;Molecular;multiplex assay;National Institute of Allergy and Infectious Disease;National Institute of Arthritis, and Musculoskeletal, and Skin Diseases;National Institute of Environmental Health Sciences;new technology;novel strategies;Participant;Pathogenicity;Patients;Penetrance;Pharmacogenetics;Phenotype;phenotypic data;Philosophy;Population;precision genomic medicine;Prevalence;Probability;Process;Productivity;programs;Proteins;Protocols documentation;Publications;Publishing;rare variant;Recommendation;Recontacts;Recording of previous events;reproductive;Research;Resources;Risk;Services;Speed;success;System;Testing;Time;tomography;Update;Variant;Vision;Work;working group

PROJECT_TITLE: Genomic Ascertainment - Molecular and Genetic Aspects


NIH_SPENDING_CATS: Attention Deficit Hyperactivity Disorder (ADHD);Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Genetics;Human Genome;Mental Health;Neurosciences;Pediatric

PROJECT_TERMS: Adult;Age;Amygdaloid structure;Anterior;Attention deficit hyperactivity disorder;Behavior;Behavioral;Behavioral Research;Brain;Brain imaging;Brain region;Child;Childhood;cingulate cortex;Clinical;Clinical Research;cohort;comorbidity;Complex;Consensus;Corpus striatum structure;Data;Data Set;Development;Diagnosis;Dorsal;Environment;Functional disorder;Functional Magnetic Resonance Imaging;Genes;Genetic;Genomics;Goals;Health;Image;Individual;Intervention;Link;Modality;Modeling;Motion;Motor;National Human Genome Research Institute;neural;neurobehavioral;neurobehavioral disorder;neuroimaging;novel strategies;Outcome;Phenotype;Publications;Research;Rest;Risk;Sample Size;social;Social Environment;Testing;trait;Youth

PROJECT_TITLE: The neurobehavioral, environmental and genetic factors impacting ADHD.


NIH_SPENDING_CATS: Clinical Research;Genetics;Human Genome;Infectious Diseases;Pediatric;Primary Immunodeficiencies;Rare Diseases

PI_NAMEs: MCGUIRE, PETER  (contact)

PROJECT_TERMS: acute infection;Animal Model;Anti-Bacterial Agents;Antibody Repertoire;Antibody Response;B-Lymphocytes;Bacterial Antibodies;Bibliography;Bioenergetics;Biological Markers;Biological Models;Cell model;Cells;Child;Clinical;clinical care;Clinical Protocols;Collaborations;Communities;comparison control;congenital immunodeficiency;Coupled;Data;Dedications;defined contribution;Dimensions;Disease;fatty acid oxidation;Flow Cytometry;Gender;Genes;Glycolysis;Goals;healthy volunteer;human subject;Humoral Immunities;Immune;immune function;immune health;Immune response;improved;Individual;Infection;infection risk;Inflammatory;insight;Interferon Type I;Interferons;Interleukin-1;Intervention;Investigation;Metabolism;Mites;Mitochondria;Mitochondrial Diseases;mitochondrial dysfunction;mitochondrial metabolism;Natural History;Natural Killer Cells;Outcome;Oxidative Phosphorylation;Oxidative Phosphorylation Deficiency;Paper;pathogen;Pathway interactions;Patients;Pattern;Peripheral Blood Mononuclear Cell;Phenotype;policy recommendation;Population;Production;Protocols documentation;response;risk mitigation;Scientific Advances and Accomplishments;Serology;Signal Transduction;single-cell RNA sequencing;Surface;T-Lymphocyte;T-Lymphocyte Subsets;Technology;Therapeutic;Therapeutic Intervention;Translating;translational research program;United States National Institutes of Health;Vaccination;Viral;Viral Antibodies;Virus Diseases;Work

PROJECT_TITLE: Metabolism, infection and immunity in inborn errors of mitochondrial metabolism


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Genetics;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Human Genome;Social Determinants of Health

PI_NAMEs: PERSKY, SUSAN  (contact)

PROJECT_TERMS: Area;Attitude;Behavior;Clinical;Communication;Communities;Data;Diabetes Mellitus;Diffusion;digital;Discrimination;Disparity;Follow-Up Studies;Genomics;health disparity;Health Promotion;Healthcare;Institutional Review Boards;Knowledge;Medical;Medical Students;Paper;Patients;polygenic risk score;Population;Provider;Publishing;Race;Reaction;Research;risk minimization;Shapes;social media;social stigma;Stigmatization;Technology;virtual reality;Visit;Weight

PROJECT_TITLE: Communication of genomic information in clinical, community, and digital contexts


NIH_SPENDING_CATS: Behavioral and Social Science;Biotechnology;Clinical Research;Genetics;Health Services;Human Genome;Precision Medicine

PROJECT_TERMS: Address;adverse outcome;Ally;Amendment;Anxiety;Area;Attitude;Behavioral;biobank;Blood specimen;Clinical;clinical care;Clinical Medicine;clinical practice;clinical sequencing;clinically relevant;Collaborations;Data;data communication;Development;diagnostic value;Disease;exome;exome sequencing;experience;Extramural Activities;Foundations;Fright;Functional disorder;Genes;Genetic Counseling;genetic counselor;genetic variant;Genets;Genome;genome sequencing;genome-wide;genomic data;Genomic medicine;genomic predictors;Genomics;Genotype;Goals;Grant;Health;Health Care Costs;health care settings;Health Services Research;Healthcare;Image;improved;Individual;individual patient;interest;Laboratories;Malignant hyperpyrexia due to anesthesia;Medical;Medicine;member;Mental Depression;Modeling;Molecular;Motivation;Muscle;neurosurgery;new technology;Overutilization of Health Services;Paper;Participant;Penetrance;Persons;Pharmacogenetics;Phenotype;phenotypic data;Physicians;Population;precision genomic medicine;Predisposition;Prevalence;programs;rare variant;Recommendation;Recontacts;Recurrence;reproductive;Research;research clinical testing;Research Personnel;Resources;Risk;screening;Site;Standard Model;Study Section;Surveys;Test Result;Testing;tomography;Variant;Vision;Work

PROJECT_TITLE: Genomic Ascertainment - Clinical and Behavioral Aspects


NIH_SPENDING_CATS: Biomedical Imaging;Clinical Research;Congenital Structural Anomalies;Genetics;Human Genome;Orphan Drug;Pediatric;Rare Diseases

PROJECT_TERMS: Agreement;Biopsy Specimen;Clinical;clinical center;Clinical Data;Clinical Research;Clinical Research Protocols;cohort;Collagen nevus of skin;Companions;Cooperative Research and Development Agreement;Coupled;Data;Development;Disease;Dose;efficacy study;Electroencephalography;Enrollment;Etiology;Genes;Genetic;Genetic Diseases;Genetic Research;Genotype;Germ Lines;Growth;Growth Disorders;Human Genetics;imaging study;In Vitro;Inherited;Laboratories;Lenz syndrome 2;Lung Diseases;malformation;Molecular;mosaic;Mosaicism;Mutation Detection;Natural History;novel therapeutics;Oncology;Operative Surgical Procedures;Other Genetics;Outcome Measure;Participant;Patients;Pharmaceutical Preparations;Phase;phase 2 study;Phenotype;Physical Examination;Polydactyly;primary outcome;Productivity;Proteus Syndrome;Publications;Pulmonary function tests;radiological imaging;Rare Diseases;Recording of previous events;research clinical testing;Resources;Safety;Sampling;Severities;Shapes;Structural defect;Syndrome;Therapeutic;Therapeutic Studies;Time;tomography;tumorigenesis;ultrasound;United States National Institutes of Health;Variant;Work

PROJECT_TITLE: Rare & Mosaic Disorders - Clinical Research


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Clinical Research;Coronaviruses;Genetics;Hematology;Human Genome;Mental Health;Microbiome;Pain Research;Prevention;Rare Diseases;Sickle Cell Disease;Social Determinants of Health;Wound Healing and Care

PROJECT_TERMS: Address;Adult;Affect;African ancestry;Agreement;All of Us Research Program;American;Anaerobic Bacteria;Anemia;Animals;Attitude;behavioral health;beta Globin;Bibliography;Biological Markers;Cardiomyopathies;carrier status;carrier testing;Case Series;Case Study;Case/Control Studies;Cells;Cessation of life;Childhood;Chronic;Chronic Kidney Failure;Clinical;clinical care;Codon Nucleotides;cohort;Cohort Studies;comorbidity;Complication;Corticosterone;Corynebacterium;COVID-19 pandemic;COVID-19 pandemic effects;Cross-Sectional Studies;current pandemic;Data;Data Collection;Data Set;Databases;Deep Vein Thrombosis;design;Diabetic Foot Ulcer;Disease;editorial;Educational Status;Electronic Health Record;emotional distress;Employment;Erythrocyte Membrane;Etiology;Exclusion;Exertion;Ferritin;Frequencies;Fright;Genes;Genetic;Genetic study;genome sequencing;Genomic approach;Genomics;Genotype;Genus staphylococcus;Goals;Guidelines;Hair;healing;Health;health assessment;Health behavior;health care quality;health care service;health care service utilization;Heart failure;Height;Hemolysis;Hemolytic Anemia;Heterozygote;Hospitalization;Hydrocortisone;Impairment;improved;In Vitro;Incidence;inclusion criteria;Individual;insight;Institution;interest;Internal Medicine;Laboratories;Leg;Leg Ulcer;Logistic Regressions;Marital Status;Medical;meeting abstracts;Mental Health;microbial community;microbial signature;microbiome;Mutation;Nature;nonEnglish language;offspring;opportunistic pathogen;Organ;Outcome;Pain;pandemic disease;Participant;pathogenic bacteria;patient population;Patient Self-Report;Patients;perceived stress;physical conditioning;Physical environment;Physiological;Point Mutation;Population;Predisposition;premature;Prevalence Study;Procedures;Process;programs;Proteinuria;psychologic;psychosocial;psychosocial wellbeing;Public Policy;Published Comment;Publishing;Pulmonary Embolism;Quality of life;Quality of Life Assessment;Random Allocation;Randomized;Recording of previous events;recruit;Recurrence;Reporting;Research;research study;resilience;Resistance;Resources;Rhabdomyolysis;Risk;Role;Sampling;SARS-CoV-2 infection;screening program;Serum;Severities;Severity of illness;Shapes;Sickle Cell;Sickle Cell Anemia;Sickle Cell Trait;Sickle Hemoglobin;skin microbiome;Sleep disturbances;social;Social Environment;Social Functioning;Social Sciences;Stress;Stroke;Surveys;Symptoms;systematic review;Thromboembolism;Time;Transfusion;Ulcer;United States;Vaccine Research;Variant;Weight;Well in self;whole genome;working group

PROJECT_TITLE: Insights into Sickle Cell Trait and  Sickle Cell Disease


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Caregiving Research;Clinical Research;Genetics;Human Genome;Rare Diseases;Social Determinants of Health

PROJECT_TERMS: Activities of Daily Living;Affect;Alzheimer's disease related dementia;Assessment tool;Behavior;Biological;Biological Markers;Blood specimen;care recipients;Caregiver well-being;Caregivers;caregiving;caregiving research;Caring;Chronic;clinical center;CLN3 gene;Cognitive;cohort;Collaborations;Consent;coping;Cross-Sectional Studies;Data;Diagnosis;diaries;Disease;emotional factor;Enrollment;expectation;experience;Family;Family health status;Goals;Health;Hereditary Disease;improved;Inborn Errors of Metabolism;Individual;informal caregiving;informant;Intervention;Interview;Iowa;Life;Longitudinal Studies;loved ones;Manuscripts;Measures;Medical;Mitochondrial Diseases;Paper;Participant;Patients;Personal Satisfaction;Persons;Phase;Pilot Projects;primary caregiver;Process;Publications;Publishing;Recording of previous events;recruit;Reporting;Research;Research Design;Resources;Role;Sampling;social factors;Social Network;social relationships;Spielmeyer-Vogt Disease;Stress;stressor;Structure;Support System;Surveys;System;Testing;United States National Institutes of Health;Universities;Visit;Work

PROJECT_TITLE: Inherited Disease, Caregiving, and Social Networks


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Childhood Obesity;Genetics;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Human Genome;Nutrition;Obesity;Pediatric;Prevention;Social Determinants of Health

PROJECT_TERMS: Agonist;Attitude;Behavior;Belief;Biological Process;Child;Communication;Communities;Data;Desire for food;Diabetes Mellitus;Diet Habits;dietary;Disinhibition;Eating;Eating Behavior;Educational Materials;Educational process of instructing;Environment;Epigenetic Process;Etiology;experience;Exposure to;Family;Family history of;Feeding behaviors;Feeding Patterns;Food;gene environment interaction;Genes;Genetic;Genomics;GLP-I receptor;Guilt;Individual;innovation;Internet;Judgment;Learning;Life;Manuscripts;member;nutrition related genetics;nutritional genomics;Obesity;obesity prevention;Outcome;Paper;Parents;Pharmaceutical Preparations;Phenotype;Population;Preparation;Process;programs;psychologic;Publishing;Reaction;Research;response;Risk;Role;Shapes;simulation;social stigma;Stigmatization;Surveys;Technology;Testing;Twitter;virtual reality;Weight;Weight maintenance regimen

PROJECT_TITLE: Eating and Feeding Behavior: Exploring Phenotypes and Influencing Outcomes


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biotechnology;Clinical Research;Genetics;Human Genome;Social Determinants of Health

PROJECT_TERMS: Area;Attitude;Behavioral Sciences;caregiving;Communication;Data;Development;disorder risk;Family;Family health status;Future;Genomics;Goals;Hereditary Disease;informant;Institutional Review Boards;instrument;Knowledge;literacy;Measurement;Measures;method development;Methodology;Methods;Modeling;National Human Genome Research Institute;novel;Phase;Protocols documentation;Recording of previous events;recruit;Research;research and development;Risk;Science;Self Efficacy;Social Environment;Social Network;Social Sciences;System;Time;tool;Validation;validation studies;Work

PROJECT_TITLE: Methodological Development


NIH_SPENDING_CATS: Brain Disorders;Down Syndrome;Genetics;Human Genome;Intellectual and Developmental Disabilities (IDD);Neurosciences;Pediatric;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

PI_NAMEs: BIANCHI, DIANA  (contact)

PROJECT_TERMS: Adoption;Affect;Age;Amniocentesis;Amyloid beta-Protein Precursor;antenatal;Antiinflammatory Effect;Antioxidants;behavioral phenotyping;bioinformatics tool;biological adaptation to stress;Biological Assay;Biological Models;Body System;Brain;Cardiovascular system;Cell Aging;cell growth;Cell Line;Characteristics;Chile;Chorionic Villi Sampling;Chromosome 16;Chromosome 21;Clinical;Clinical Management;Collaborations;Collection;Cytogenetics;cytotoxicity;Data;Data Set;Databases;Development;Diagnosis;Diagnostic Procedure;Disease;diverse data;Down's Syndrome;drug candidate;Early treatment;Embryo;Evaluation;Exhibits;fetal;Fetal Development;Fetus;Fibroblasts;Future;Gene Expression;Gene Expression Profile;Gene Expression Profiling;Gene Proteins;Genes;Genomics;Goals;Growth;Human;Human Chromosomes;improved;in vitro Model;Individual;induced pluripotent stem cell;Infant;insight;Intellectual functioning disability;inter-individual variation;interest;Interferons;Laboratories;Libraries;Life;life span;Literature;Macrophage;Maps;Measures;Medical center;Microglia;Mitochondria;Modeling;Molecular;mouse model;mouse Trisomy 16;mouse Ts65Dn;Mus;Musculoskeletal System;National Institute on Aging;nerve stem cell;Network-based;Neurocognition;neuroinflammation;Neurologic;novel;Outcome;Oxidative Stress;Pathway interactions;Persons;Pharmaceutical Preparations;Phenotype;Placenta;Placentation;postnatal;pre-clinical;pregnant;prenatal;prenatal testing;prenatal therapy;Proliferating;protein expression;Proteome;Publications;Publishing;Quality of life;racial diversity;Research;response;Role;Safety;Sampling;screening;senescence;sex;Signal Transduction;skills;small molecule;superoxide dismutase 1;Supportive care;Therapeutic;Therapeutic Intervention;Time;transcriptome;transcriptome sequencing;transcriptomics;treatment response;Trisomy;Work

PROJECT_TITLE: Prenatal Treatment of Down Syndrome to Improve Brain Development and Neurocognition


NIH_SPENDING_CATS: Biomedical Imaging;Cancer;Cancer Genomics;Clinical Research;Clinical Trials and Supportive Activities;Genetic Testing;Genetics;Human Genome;Maternal Health;Pediatric;Pregnancy;Prevention;Rare Diseases;Women's Health Research

PROJECT_TERMS: acronyms;Adrenocortical Carcinoma;Algorithms;Amniocentesis;Aneuploidy;Asian;Awareness;Benign;Biochemistry;Biocompatible Materials;Biological;Black race;Blinded;Blood;Canada;cancer diagnosis;cell free DNA;Chorionic Villi Sampling;Chromosomal Gain;Chromosomal Loss;Chromosomes;circulating DNA;Clinical;clinical care;clinical center;Clinical Data;Clinical Management;clinical sequencing;cohort;Colorectal Cancer;continuing medical education;Detection;detection method;Diagnosis;Diagnostic;Diagnostic tests;DNA;DNA analysis;DNA Sequence;DNA sequencing;Eligibility Determination;Enrollment;Evaluation;fetal;Fetus;follow-up;Genetic;Genomics;Guidelines;Hematopoiesis;Hematopoietic System;high risk;Hispanic;Hospitals;Image;Individual;International;Israel;Karyotype;Laboratories;Lymphoma;Magnetic Resonance Imaging;Malignant - descriptor;Malignant Breast Neoplasm;Malignant Neoplasms;Maps;Medical;Medical Oncologist;meetings;Mosaicism;multidisciplinary;Natural History;Nature;Neonatal;Neoplasms;Non-Malignant;Not Hispanic or Latino;obstetric care;Participant;Patau's syndrome;Pattern;Peer Review;Physical Examination;Physicians;Placenta;Plasma;Plasma Cells;Positive Test Result;Postpartum Period;Predictive Value;Pregnancy;pregnant;Pregnant Women;prenatal;Prenatal care;prenatal testing;Professional Organizations;Provider;Proxy;Publications;Published Comment;Publishing;Race;rare cancer;reference genome;Reporting;Retrospective Studies;Risk;Sampling;screening;Screening for cancer;Serum;symposium;Test Result;Testing;Time;Time Study;tumor;Twin Multiple Birth;Ultrasonography;ultrasound;United States;Uterine Fibroids;whole body imaging;Woman;Work;Writing

PROJECT_TITLE: Natural history and evaluation of abnormal or nonreportable NIPT results and its association with maternal neoplasia


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biotechnology;Genetics;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Hematology;Human Genome;Racial and Ethnic Minority Health Research;Rare Diseases;Sickle Cell Disease;Social Determinants of Health

PROJECT_TERMS: Address;Adult;Advocacy;Advocate;Attenuated;Attitude;Awareness;Biomedical Research;black women;Child;Clinical;clinical care;Clinical Data;Clinical Trials;Clustered Regularly Interspaced Short Palindromic Repeats;cohort;Communities;community organizations;Decision Making;Descriptor;Development;Diffusion;Disease;education resources;Educational Materials;Equity;Ethnic Origin;Ethnic Population;Focus Groups;Future;gene therapy;Genes;Genetic;Genetic Variation;Genomic medicine;Genomics;Germ Lines;Goals;Government;Health;Healthcare;Hematologist;Human Genetics;improved;Individual;Industry;Institution;low income country;Medical;Medicine;meetings;Methods;Minority;novel;Parents;Patient Care;Patient Education;Patients;Physicians;Population;preference;prenatal testing;Process;Provider;psychologic;public trust;Publishing;Race;racial population;Recommendation;Recording of previous events;Research;Research Personnel;research study;Resource-limited setting;Resources;Risk;Sampling;Science;Services;Sickle Cell Anemia;Sickle Cell Trait;Social isolation;Social Network;Social Power;Societies;Sociology;US State;Validation;willingness;Woman;Work

PROJECT_TITLE: Examining the Equitable Integration of Genomics in Health Care and Society


NIH_SPENDING_CATS: Aging;Biotechnology;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Gene Therapy;Gene Therapy Clinical Trials;Genetics;Human Genome;Neurodegenerative;Neurosciences;Pediatric;Rare Diseases

PI_NAMEs: TIFFT, CYNTHIA  (contact)

PROJECT_TERMS: Adaptive Behaviors;Adolescent;Adult;Agreement;Alzheimer's Disease;autosome;base editing;biobank;Blood;blood-brain barrier crossing;Brain;Candidate Disease Gene;candidate validation;Cell model;Cerebrospinal Fluid;Child;Childhood;Clinic;Clinical;Clinical Management;cohort;Collaborations;Compensation;Coupled;Data;data sharing;design;Development;Diagnosis;Disease;Disease Progression;Enrollment;enzyme deficiency;Enzymes;exhaust;extend lifespan;Family;fetal;Fibroblasts;first-in-human;Functional disorder;G(M2) Ganglioside;Galactosialidosis;Gangliosides;Gangliosidoses GM2;Gangliosidosis GM1;Gene Expression;gene therapy;Gene therapy trial;Gene Transfer;Generations;Genes;genome wide screen;GLB1 gene;Glycoprotein Degradation Pathway;Glycoproteins;Glycosphingolipids;Human;humanized mouse;impression;improved;Individual;infancy;Infant;inhibitor;Intervention Trial;Intravenous;Laboratories;Lead;life span;Lipomucopolysaccharidoses;manufacture;Massachusetts;medical schools;Mission;Molecular;mouse model;Multicenter Trials;Mus;Mutation;National Institute of Diabetes and Digestive and Kidney Diseases;Natural History;Neurodegenerative Disorders;Neurologist;novel therapeutics;Nursing Research;Outcome;Outcome Measure;Parkinson Disease;Pathogenesis;Pathway interactions;patient expectation;Patients;Phase;Phenotype;Postbaccalaureate;Postdoctoral Fellow;Pregnancy;Process;Production;programs;prospective;Prospective Studies;Publications;Publishing;Rare Diseases;Reporting;Research;Research Design;safe patient;Sandhoff Disease;Site;small molecule;Sphingolipids;Symptoms;Tay-Sachs Disease;Techniques;Testing;Therapeutic;Therapeutic Intervention;Tissues;tractography;trial design;United States National Institutes of Health;Universities;Urine;vector;white matter;Work

PROJECT_TITLE: Pathogenesis Informs Therapy for Glycosphingolipid and Glycoprotein Disorders


NIH_SPENDING_CATS: Clinical Research;Genetics;Human Genome

PI_NAMEs: GUNTER, CHRISTIE  (contact)

PROJECT_TERMS: Access to Information;Advocacy;Anniversary;Appearance;Area;Biomedical Research;Collection;Communication;Communication Research;Communities;Complex;demographics;design;Desire for food;Development;Discipline;Educational workshop;effectiveness measure;efficacy evaluation;Ensure;Environment;Evaluation;evidence base;Evidence based practice;expectation;experience;Exposure to;Extramural Activities;Foundations;Frequencies;Funding;Future;General Population;Goals;Government;Health;Health Priorities;Home;Individual;Industry;insight;Institution;interdisciplinary collaboration;interest;Interest Group;Intramural Research;Investments;Journals;Laboratories;Learning;meetings;member;Methodology;Methods;Misinformation;Mission;Modernization;Output;Participant;preference;pressure;Printed Media;Printing;Privatization;Productivity;Proliferating;Publishing;rare condition;Reporting;Research;Research Personnel;Research Priority;Resources;Respondent;response;Rice;Role;Sampling Biases;Scholarship;Science;Scientist;skills;social media;Students;success;Survey Methodology;Surveys;Television;Training;training opportunity;Uncertainty;United States;United States National Institutes of Health;Universities;Work

PROJECT_TITLE: Mixed-Methods Studies of Science Communication


NIH_SPENDING_CATS: American Indian or Alaska Native;Genetic Testing;Genetics;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Human Genome;Patient Safety;Precision Medicine;Prevention;Racial and Ethnic Minority Health Research

PI_NAMEs: MANOLIO, TERI  (contact)

PROJECT_TERMS: absorption;actionable mutation;Alleles;Area;arm;Biological Assay;Classification;Clinical;clinical care;Clinical Data;clinical diagnosis;Clinical Research;cohort;Collaborations;Consultations;Critical Pathways;Data;Databases;Diagnosis;editorial;Educational Materials;Electronic Health Record;Environment;ethnic difference;European;Excretory function;Frequencies;Funding;Gene Frequency;Genes;genetic testing;Genomic medicine;Genomics;Goals;Guidelines;Health;Hospitals;improved;Indigenous American;informatics tool;Knowledge;Latino;Manuscripts;Maryland;Medical center;Metabolism;non-genetic;Other Genetics;Patients;Pharmaceutical Preparations;pharmacogenetic variants;Pharmacogenetics;Pharmacogenomics;Population;Precision Health;Prevention;Principal Investigator;Provider;racial difference;Reporting;Research;response;symposium;Testing;Translating;Underrepresented Populations;Universities;user-friendly;Variant;Work

PROJECT_TITLE: Genomic Medicine Implementation Unit


PI_NAMEs: SHCHELOCHKOV, OLEG  (contact)

PROJECT_TERMS: Affect;Awareness;Biochemical;Biomedical Research;Blood specimen;Body Fluids;Caring;Clinical;Clinical Management;Clinical Research;Collaborations;Data;Dietary Factors;Disease;DNA;eligible participant;enzyme activity;Enzymes;Frequencies;gastrointestinal;Genes;Genetic;Genetic Diseases;genetic variant;Genomics;Hospitalization;Image;imaging study;improved;Inborn Errors Purine-Pyrimidine Metabolism;industry partner;Laboratories;Laboratory Study;Link;Medical;metabolic abnormality assessment;microbiome;microbiome analysis;Mission;Natural History;next generation;novel;novel marker;Nutritional;Outcome;Participant;Pathogenicity;Pharmaceutical Preparations;pharmacologic;predictive modeling;primary endpoint;purine metabolism;Purines;pyrimidine metabolism;pyrimidine metabolism disorder;Pyrimidines;Quality of life;Recording of previous events;Sampling;secondary endpoint;skin biopsy;Study Subject;Tissue Sample;United States National Institutes of Health;Variant

PROJECT_TITLE: Purine and Pyrimidine Metabolism Unit


NIH_SPENDING_CATS: Clinical Research;Clinical Trials and Supportive Activities;Genetics;Human Genome;Networking and Information Technology R&D (NITRD)

PROJECT_TERMS: Caring;Clinical;clinical practice;clinical research site;Clinical Trials;cybersickness;Data;experience;extended reality;Future;Health;Individual;Intervention;Medical;Medical Technology;Medicine;Motion Sickness;Patient Education;Preparation;Publishing;Recommendation;Technology;technology intervention;Therapeutic;Time;tool;Training;Virtual and Augmented reality;virtual reality;Work

PROJECT_TITLE: Immersive technologies in health and medicine


ACTIVITY: ZIC

ADMINISTERING_IC: AG

IC_NAME: NATIONAL INSTITUTE ON AGING

ORG_NAME: NATIONAL INSTITUTE ON AGING

PI_NAMEs: FERRUCCI, LUIGI  (contact)

PROJECT_TERMS: Age;age-related disease;aging related;Biology of Aging;Capital;Cloud Computing;disability;Equipment;equipment acquisition;Information Technology;Infrastructure;instrument;Investments;Laboratories;Methylation;programs;Research;Services;single cell genomics;Technology

PROJECT_TITLE: Capital Equipment  General


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Dementia;Disability Research

PROJECT_TERMS: Address;Age;Aging;Agreement;Autopsy;Baltimore;Biological;Blood specimen;Cardiovascular system;Cells;Clinic;Clinic Visits;Clinical Chemistry Tests;Clinical Research;Cognitive;Consent;Contracts;Databases;Dedications;Dementia;disability;Disease;Eligibility Determination;end of life;Enrollment;Event;Family;follow-up;frailty;Health;health assessment;Health Status;Healthcare;Home;Home visitation;Hospitals;human old age (65+);Impaired cognition;Individual;Informed Consent;interest;Longitudinal Studies;Malignant Neoplasms;mortality;Nursing Services;Outcome;Outcome Measure;Participant;participant enrollment;Persons;Physiological;Plasma;programs;Resources;Serum;Specimen;Subgroup;Telephone;Telephone Interviews;Time;Update;Visit;Visiting Nurse;willingness

PROJECT_TITLE: The BLSA Home Visit Program


ADMINISTERING_IC: CL

IC_NAME: CLINICAL CENTER

ORG_NAME: CLINICAL CENTER

PI_NAMEs: FRANK, JOSEPH  (contact)

PROJECT_TERMS: Academic Training;antagonist;Atherosclerosis;Basic Science;Biology;cell motility;Chemistry;Clinical;clinical center;Clinical Sciences;Colonic Polyps;Contrast Media;Core Facility;Development;Diagnostic radiologic examination;Doctor of Philosophy;Equipment;Goals;Image;image guided intervention;imager;imaging scientist;in vivo;Infrastructure;Integrins;Intervention;Intramural Research Program;Laboratories;Liposomes;Magnetic Resonance Imaging;Metabolic;Methods;microPET;Microscopy;Molecular;Molecular Biology;molecular imaging;multidisciplinary;Multimodal Imaging;multimodality;multiparametric imaging;nanoparticle;novel diagnostics;novel therapeutics;Pathologic;Positron-Emission Tomography;programs;Radioactive;radiologist;Radiology Specialty;reflectance confocal microscopy;Research;Research Personnel;Resources;Rodent Model;Science;Scientist;Services;stem cells;Synthesis Chemistry;System;tissue culture;trafficking;Training;Training Programs;Translational Research;X-Ray Computed Tomography

PROJECT_TITLE: Core Research Services for Molecular Imaging and Imaging Sciences


PI_NAMEs: LEVIN, RONALD  (contact)

PROJECT_TERMS: AFP gene;Artificial Intelligence;Bite;Cardiovascular system;Clinical;clinical center;Clinical Sciences;cloud storage;Collaborations;Communities;Computers;Data;data anonymization;Data Storage and Retrieval;deep learning;Digital Imaging and Communications in Medicine;Directories;Disasters;Fostering;Image;Image Analysis;image processing;image visualization;Individual;Information Systems;Libraries;Licensing;Linux;Medical Imaging;member;Metadata;multicore processor;petabyte;Picture Archiving and Communication System;radiological imaging;Radiology Specialty;Recovery;Research;Rest;Security;Site;Speed;System;systems research;tool;United States National Institutes of Health;virtual machine;Visualization

PROJECT_TITLE: MRIPS


PI_NAMEs: CHANOCK, STEPHEN J. (contact)

PROJECT_TERMS: Address;Advanced Technology Center;analytical tool;Area;Basic Science;Biological;Biological Assay;Cancer Etiology;cancer genetics;cancer genomics;Candidate Disease Gene;Clinical;Custom;Data;Data Storage and Retrieval;design;Division of Cancer Epidemiology and Genetics;DNA;DNA sequencing;Electronics;Employment;Epidemiologist;Equipment and supply inventories;Family;Gene Chips;Genetic;genetic analysis;Genetic Fingerprintings;genetic linkage analysis;Genetic Markers;Genetic Variation;genome wide association study;Genotype;Germ Lines;Heritability;high risk;Human;Informatics;Information Management;instrument;Intramural Research Program;Laboratories;Laboratory Research;Malignant Neoplasms;Management Information Systems;Mission;NCI Center for Cancer Research;new technology;next generation sequencing;operation;Outcome;population based;Predisposition;Preparation;Principal Investigator;Process;quality assurance;Quality Control;Residual state;Sampling;Scientist;Series;Signal Transduction;Statistical Methods;System;Technology;translational genomics;whole genome;Work

PROJECT_TITLE: Cancer Genomics Research Laboratory


PI_NAMEs: BLACK, AMANDA  (contact)

PROJECT_TERMS: biobank;Biological Assay;Biological Specimen Banks;Collection;Division of Cancer Epidemiology and Genetics;DNA;epidemiology study;Genotype;Laboratories;Methods;Molecular Epidemiology;Population;repository;Research;Sampling;Services

PROJECT_TITLE: Biorepository Processing, Storage, and Research


PI_NAMEs: HENDERSON, MARIANNE  (contact)

PROJECT_TERMS: Androgens;Biological Assay;Biomedical Research;Dedications;Development;Division of Cancer Epidemiology and Genetics;Estrogens;Hormones;Human;Infrastructure;Laboratories;liquid chromatography mass spectrometry;Measurement;Measures;method development;Population Study;Production;Proteomics;Techniques;Technology

PROJECT_TITLE: Endogenous Hormone Measurement Production Assay Infrastructure at the FNLCR


PI_NAMEs: KRAFT, PETER  (contact)

PROJECT_TERMS: Address;Adult;Age;biobank;Biological;Biological Markers;Cancer Etiology;cancer risk;clinical infrastructure;cohort;Cohort Studies;Computerized Medical Record;cost effective;Data;Development;Division of Cancer Epidemiology and Genetics;Drug Prescriptions;Electronics;follow-up;Future;Health Maintenance Organizations;Length;Medical;Medical Records;Military Personnel;next generation;novel;Outcome;Participant;Procedures;Productivity;prospective;Questionnaires;Recording of previous events;Records;Research;Resources;Risk Factors;Running;sample collection;Sampling;Stable Populations;System;Time;tissue archive;Tumor Tissue;Vertebral column;Work;working group

PROJECT_TITLE: Cohort and Biobank Development


PI_NAMEs: TURNER, CLESSON  (contact)

PROJECT_TERMS: Address;American;analysis pipeline;Bioinformatics;bioinformatics pipeline;Blood specimen;Cassia;Chicago;CLIA certified;Clinical;clinical center;Clinical Data;Clinical Protocols;Clinical Research;clinically relevant;cohort;Collaborations;Collection;college;Communities;Compensation;Data;data de-identification;data harmonization;Data Storage and Retrieval;Databases;Development;Disease;Electronic Health Record;Eligibility Determination;eligible participant;Enrollment;Ensure;Environment;Evaluation;exome;Festival;Genes;Genetic Counseling;genetic counselor;Genetic Research;genetic variant;Genetic Variation;Genome;genome browser;genomic data;Genomics;Genotype;Goals;Healthcare Systems;human disease;Human Genetics;Individual;Infrastructure;insertion/deletion mutation;interest;Investigation;Joints;Journals;Knowledge;Laboratories;Lead;Leadership;Link;Manuscripts;Measures;Mediation;Medical Genetics;Methodology;Molecular;National Cancer Institute;National Human Genome Research Institute;National Institute of Allergy and Infectious Disease;National Institute of Environmental Health Sciences;Nature;novel;Nursing Research;operation;Paper;Participant;Patient Recruitments;Persons;Phase;Phenotype;phenotypic data;posters;Precision Health;precision medicine;Principal Investigator;Process;programs;Protocols documentation;Publishing;Recontacts;recruit;Recruitment Activity;Reporting;Research;Research Activity;research clinical testing;Research Personnel;Research Project Grants;research study;Resources;Schedule;Scientist;Single Nucleotide Polymorphism;Site Visit;Societies;Source;Specialist;success;symposium;Testing;Time;tool;Travel;United States National Institutes of Health;Update;Variant;variant of interest;Washington;web site;Work

PROJECT_TITLE: Reverse Phenotyping Core


NIH_SPENDING_CATS: Autoimmune Disease;Cancer;Cancer Genomics;Cardiovascular;Genetics;Health Disparities and Racial or Ethnic Minority Health Research;Hematology;Human Genome;Lupus;Prevention;Racial and Ethnic Minority Health Research;Rare Diseases;Sickle Cell Disease

PI_NAMEs: DENNY, JOSHUA  (contact)

PROJECT_TERMS: 17p;6p21;Adult Glioma;African American population;African ancestry;Aftercare;Age;Algorithms;Alleles;Allopurinol;amino acid metabolism;Amyloidosis;analysis pipeline;Anemia;Anus;Atlases;autoimmune rheumatologic disease;BANK1 gene;Behavior;beta Thalassemia;biobank;Biochemical Pathway;Black race;Blood Pressure;Blood Vessels;Bone necrosis;cancer classification;cancer genomics;cancer type;Cardiovascular Diseases;cardiovascular risk factor;Carpal Tunnel Syndrome;Case Series;Catalogs;causal variant;Clinical;clinical heterogeneity;clinical phenotype;cohort;Collaborations;computable phenotypes;Computer Analysis;Data;Diagnosis;Diet;Disease;disease phenotype;Disease Progression;Early identification;Electronic Health Record;enzyme activity;Evaluation;Event;Exclusion;Folic Acid;follow-up;Frequencies;Genes;Genetic;genetic architecture;Genetic Predisposition to Disease;Genetic Risk;genetic variant;Genome;genome wide association study;genomic data;Genomics;Genotype;Goals;Gout;Growth;Guidelines;Head and Neck Cancer;Health;Heart failure;Hemoglobinopathies;Heterozygote;High Prevalence;high risk;Hispanic;HLA-B Antigens;Homocysteine;Hyperparathyroidism;Hypertension;improved;Individual;interest;Iron deficiency anemia;ITGAM gene;Laboratories;Link;Logistic Regressions;Major Depressive Disorder;Malignant Breast Neoplasm;Malignant Neoplasms;Measurement;Mentors;Meta-Analysis;Metabolism;Methylenetetrahydrofolate reductase (NADPH);Micro Array Data;mutant;Mutation;National Human Genome Research Institute;Neoplasms;novel;Online Mendelian Inheritance In Man;Participant;Pattern;Pharmaceutical Preparations;phenome;Phenotype;Polyadenylation;Population;Population Heterogeneity;Prealbumin;Predisposition;Pregnancy;Prevalence;Primary Myocardial Diseases;Prognosis;prognostication;programs;Proxy;Pulmonary Embolism;purine metabolism;Purines;Pyrimidine;pyrimidine metabolism;Rare Diseases;rare mendelian disorder;Rectal Polyp;Renal function;Reporting;Research;Research Personnel;Risk;Role;Scientist;screening;Services;Severities;Sickle Cell Trait;Signal Transduction;social;STAT4 gene;Subgroup;Syndrome;Systemic Lupus Erythematosus;Testing;The Cancer Genome Atlas;Thrombosis;Time;Tissues;TP53 gene;Training;tumor;United States National Institutes of Health;Uric Acid;Uterine Fibroids;Validation;Variant;Work

PROJECT_TITLE: Cohort Analytics Core


ACTIVITY: ZID

NIH_SPENDING_CATS: Alcoholism, Alcohol Use and Health;Behavioral and Social Science;Bioengineering;Clinical Research;Genetics;Human Genome;Networking and Information Technology R&D (NITRD);Substance Misuse

PROJECT_TERMS: alcohol abuse therapy;alcohol use disorder;Attention deficit hyperactivity disorder;Augmented Reality;Behavioral Research;Clinical;clinical center;Communication;Computer software;Consultations;Data;Data Analyses;Data Collection;data wrangling;Education;Environment Design;Family;Future;gene environment interaction;Genetic Diseases;Genetic Risk;Genomics;Healthcare;healthcare community;Industry;innovation;Intervention;Intervention Studies;Libraries;Medical;Methods;Minor;Motion Sickness;National Human Genome Research Institute;Physiological;Play;Preparation;programs;psychologic;Public Health;remote location;Reporting;Research;Research Design;Research Methodology;Research Project Grants;Resources;response;Role;Services;Shapes;simulation;social;Software Design;Stimulus;Technology;tool;United States National Institutes of Health;Virtual and Augmented reality;virtual environment;virtual reality;virtual reality environment;visual tracking;Work

PROJECT_TITLE: Immersive Simulation Program


ACTIVITY: ZIE

ADMINISTERING_IC: AR

IC_NAME: NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES

NIH_SPENDING_CATS: Arthritis;Autoimmune Disease;Clinical Research;Health Services;Lupus;Pediatric;Rare Diseases;Rheumatoid Arthritis

PI_NAMEs: DEMARCO, PAUL  (contact)

PROJECT_TERMS: Accreditation;Adult-Onset Still's Disease;Agonist;American;Ankylosing spondylitis;Antibodies;Area;Arthritis;Autoimmune Diseases;Blood Vessels;Businesses;cardiovascular risk factor;career;case-by-case basis;Certification;Child;Childhood;Cities;Clinic;Clinical;clinical care;clinical center;Clinical Research;clinical training;Community Health;Connective Tissue Diseases;Continuity of Patient Care;cytokine;Dedications;Degenerative polyarthritis;Dermatomyositis;Disease;District of Columbia;Educational Curriculum;Educational process of instructing;Eligibility Determination;Event;Faculty;Fellowship;Fellowship Program;Fever;Fibromyalgia;Functional disorder;Genetic;Gout;graduate medical education;Guidelines;immunoregulation;improved;Inclusion Body Myositis;Infectious Arthritis;Inflammatory;Infusion procedures;Inherited;inhibitor;Inpatients;Institution;Investigation;Journals;Juvenile Dermatomyositis;lectures;Length of Stay;Lupus;matriculation;Medical center;Medical Examiners;medical schools;meetings;Melorheostosis;Mentors;minority communities;Myositis;National Institute of Arthritis, and Musculoskeletal, and Skin Diseases;Natural History;omalizumab;Oral;Osteoporosis;Outcome;Outpatients;participant enrollment;Pathogenesis;Patient Care;Patients;Periodicals;Polymyositis;Positioning Attribute;PPAR gamma;Prevention;programs;Protocols documentation;Pseudogout;Research;Research Activity;Research Project Grants;Research Training;Rheumatism;Rheumatoid Arthritis;Rheumatology;Role;Rotation;Safety;Sarcoidosis;Science;Services;Site;Societies;Spinal Fusion;Spondylarthritis;symposium;Syndrome;systemic juvenile idiopathic arthritis;Systemic Lupus Erythematosus;Systemic Scleroderma;Time;TNF gene;Training;Training Programs;Translational Research;United States National Institutes of Health;Universities;Vasculitis;ward;Washington

PROJECT_TITLE: Clinical Training in Rheumatology


ADMINISTERING_IC: GM

IC_NAME: NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

PI_NAMEs: FALCON-MORALES, EDGARDO  (contact)

PROJECT_TERMS: Amber;Area;Biochemistry;Bioinformatics;Biophysics;career;career development;career networking;Cellular biology;Colon;Developmental Biology;Doctor of Philosophy;Environment;experience;Genetic;Goals;Immunology;Individual;Intramural Research;Laboratory Research;Leadership;Mentors;Mission;Molecular Biology;National Center for Advancing Translational Sciences;National Heart, Lung, and Blood Institute;National Human Genome Research Institute;National Institute of Allergy and Infectious Disease;National Institute of Child Health and Human Development;National Institute of Diabetes and Digestive and Kidney Diseases;National Institute of Drug Abuse;National Institute of Environmental Health Sciences;National Institute of General Medical Sciences;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;National Institute on Alcohol Abuse and Alcoholism;Neurosciences;Organism;Pharmacology;Physiology;Positioning Attribute;post-doctoral training;Postdoctoral Fellow;programs;Publications;Reporting;Research;Research Project Grants;Research Training;Science;Structure;technology development;Training;training opportunity;Training Programs;United States National Institutes of Health;United States National Library of Medicine;Veronica;ward

PROJECT_TITLE: Postdoctoral Research Associate Training Program (PRAT)


ACTIVITY: ZIG

NIH_SPENDING_CATS: Aging

PI_NAMEs: WILGENBURG, BRIAN  (contact)

PROJECT_TERMS: Accreditation;Advisory Committees;age related;age-related disease;Aging;animal care;Animal Care and Use Committees;Animal Experimentation;animal old age;Animal Welfare;Animals;Area;behavior test;behavioral phenotyping;Behavioral Research;Biology of Aging;Biomedical Research;biosecurity;Breeding;Caring;Cognitive;comparative;Contractor;Contracts;COVID-19;Educational process of instructing;Ensure;Facility Accesses;Genotype;Guidelines;Health;Housing;improved;International;Investigation;Laboratory Animals;Measures;Medicine;meetings;member;Mission;Motor;Mus;novel;Performance;Periodicals;Personal Satisfaction;Privatization;Procedures;programs;Regulation;Reporting;Reproducibility;Research;Research Personnel;Research Project Grants;Resources;sample collection;Sampling;Science;Services;Site Visit;Special needs;Techniques;Testing;Training;treatment research;United States National Institutes of Health;Update;Work

PROJECT_TITLE: NIA IRP Comparative Medicine Section