NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Behavioral and Social Science;Brain Disorders;Clinical Research;Dementia;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Neurodegenerative;Prevention;Social Determinants of Health

PI_NAMEs: BRONAS, ULF G (contact)

PROJECT_TERMS: Address;Administrator;Aging;Alzheimer's disease related dementia;Area;Award;Behavioral;behavioral and social science;brain health;career;career development;classism;Cognitive aging;cohort;college;Communication;Communities;community partners;Data;design;Development;Development Plans;Discipline;Doctor of Philosophy;early-career faculty;education planning;education research;Educational workshop;Emotional;equity, diversity, and inclusion;Ethnic Origin;Evaluation;Exclusion;experience;Extramural Activities;Faculty;Funding;Goals;Grant;Health;health disparity;health equity;health inequalities;Health Promotion;Health Sciences;Home;Immigrant;Impaired cognition;improved;Individual;Inosine Diphosphate;Instruction;interest;Intervention;intervention effect;K-Series Research Career Programs;Life Cycle Stages;member;Mentors;Mentorship;Midwestern United States;Minority;Mission;Modeling;Monitor;multidisciplinary;older adult;Outcome;Participant;Peer Review;Physical activity;Pilot Projects;population health;Population Heterogeneity;Population Sciences;Productivity;Program Appropriateness;programs;Psychosocial Assessment and Care;Public Health Schools;Qualifying;racism;recruit;Research;Research Personnel;Resources;responsible research conduct;Risk Reduction;role model;Scholarship;Science;Scientist;skills;social;social culture;social science research;Social support;success;synergism;Target Populations;Testing;Time Management;Training;Translations;Work


ADMINISTERING_IC: AG

ARRA_FUNDED: N

FUNDING_MECHANISM: RESEARCH CENTERS

IC_NAME: NATIONAL INSTITUTE ON AGING

NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Behavioral and Social Science;Brain Disorders;Dementia;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Neurodegenerative;Prevention;Racial and Ethnic Minority Health Research;Social Determinants of Health

ORG_CITY: Chicago

ORG_COUNTRY: UNITED STATES

ORG_FIPS: US

ORG_NAME: UNIVERSITY OF ILLINOIS AT CHICAGO

ORG_STATE: IL

PI_NAMEs: MITCHELL, UCHECHI ACHOLONU (contact)

PROJECT_TERMS: Address;Adult;African American;Alzheimer's disease related dementia;Area;Asian Americans;Black race;Catchment Area;Chicago;Cities;clinical center;Clinical Sciences;Cognitive aging;Collaborations;collaboratory;Communication;Communities;community advisory board;community engaged research;community engagement;Community Outreach;community partners;Country;Economics;ethnic disparity;ethnic diversity;Ethnic Origin;evidence base;Feedback;Fostering;Future;Goals;Health;health equity;Health Promotion;Hispanic;Hispanic-serving Institution;human old age (65+);Illinois;Infrastructure;Institution;Justice;Latina;Latino;Latinx;Leadership;Life Cycle Stages;Linguistics;Lived experience;Location;member;Mentors;Midwestern United States;Minority;Minority-Serving Institution;Modeling;Native Americans;older adult;Pacific Island Americans;Persons;Play;Population;population health;Population Sciences;Positioning Attribute;Primary Prevention;Process;Public Health Schools;Race;racial disparity;racial diversity;recruit;Research;residential segregation;Resources;Risk;Risk Reduction;Role;Scholarship;Scientist;Secondary Prevention;Secondary to;Side;social;socioeconomics;Structural Racism;successful intervention;Training;training opportunity;Translational Research;Translations;United States;Universities;urban area;Work

PROJECT_TITLE: Community Liaison and Recruitment Core


ED_INST_TYPE: SCHOOLS OF MEDICINE

FUNDING_MECHANISM: NON-SBIR/STTR RPGS

NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease Related Dementias (ADRD);Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Amyotrophic Lateral Sclerosis (ALS);Brain Disorders;Dementia;Frontotemporal Dementia (FTD);Genetics;Neurodegenerative;Neurosciences;Rare Diseases;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

ORG_CITY: WORCESTER

ORG_DEPT: NEUROLOGY

ORG_NAME: UNIV OF MASSACHUSETTS MED SCH WORCESTER

ORG_STATE: MA

PHR: Narrative Frontotemporal dementia is a major presenile dementia and shares common pathogenic mechanisms with the motor neuron disease ALS. GGGGCC repeat expansion in C9ORF72 is the most common genetic cause of both FTD and ALS. We will use cryo-electron microscopy and high-resolution template matching (HRTM) to investigate structural mechanisms of ribosomal defects in C9ORF72 patient neurons. If successful, these studies will open a new paradigm for developing novel therapeutic approaches for these disorders.

PI_NAMEs: GAO, FEN-BIAO  (contact);KOROSTELEV, ANDREI

PROGRAM_OFFICER_NAME: YANG, AUSTIN JYAN-YU

PROJECT_TERMS: Address;Affect;Alzheimer's Disease;American;Amyotrophic Lateral Sclerosis;Animal Model;Anterior;Arginine;Atrophic;Autophagocytosis;Autopsy;Binding;Brain;brain tissue;C9ORF72;Cell model;Cell Nucleus;Cells;Clinical;Cryoelectron Microscopy;Data;Defect;Dementia;Development;Dipeptides;Disease;Disinhibition;DNA Damage;DNA Sequence Alteration;Early Diagnosis;Empathy;Event;Extracellular Space;frontal lobe;Frontotemporal Dementia;frontotemporal lobar dementia amyotrophic lateral sclerosis;G-Quartets;Genes;Genetic;Human;Impaired cognition;Impairment;In Situ;In Vitro;Induced pluripotent stem cell derived neurons;inhibitor;Initiator Codon;Introns;Language;language impairment;Messenger RNA;Methods;Mitochondria;Molecular;molecular pathology;Motor Neuron Disease;mouse model;Movement;nanomolar;Nerve Degeneration;Neurodegenerative Disorders;Neurons;Neurosciences Research;neurotoxicity;novel therapeutic intervention;nucleocytoplasmic transport;Pathogenicity;Pathologic;Pathway interactions;patient derived induced pluripotent stem cells;Patient imaging;Patients;Peptides;Peptidyltransferase;Personality;polypeptide;Presenile Dementia;Production;Proteins;Records;research and development;Resolution;ribosome profiling;Ribosomes;RNA;Role;Social Behavior;stress granule;structural biology;Structure;System;Temporal Lobe;Therapeutic;therapeutic development;Time;tool;Toxic effect;Translating;Translational Regulation;Translational Repression;Translations

PROJECT_TITLE: Cryo-EM Analysis of Ribosomal Defects in C9ORF72-Associated Frontotemporal Dementia and ALS

STUDY_SECTION_NAME: Special Emphasis Panel[ZRG1-AN-C(02)M]


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Dementia;Neurodegenerative;Neurosciences

ORG_CITY: Jupiter

ORG_NAME: MAX PLANCK FLORIDA CORPORATION

ORG_STATE: FL

PHR: The hippocampus receives extensive cholinergic inputs that play a critical role in learning and memory.  Reduction of cholinergic inputs is a hallmark of dementia and Alzheimer's diseases; Revealing how  hippocampal cholinergic inputs mediate both memory formation and memory stability will provide insights  into understanding mnemonic processing, both in health and in neurodegenerative disorders.

PI_NAMEs: WANG, YINGXUE  (contact)

PROGRAM_OFFICER_NAME: THOMAS, CIBU PAUL

PROJECT_TERMS: Acetylcholine;Address;Aging;Alzheimer's Disease;Alzheimer's disease patient;Animals;Arousal;Attention;attentional modulation;awake;basal forebrain;Behavior;Behavioral;Brain region;cell type;Cells;Choline;cholinergic;Cholinergic Receptors;Code;Compensation;Computer Models;Cues;Data;Dementia;Dendrites;design;Deterioration;Development;Disease;Elements;Environment;Episodic memory;Event;experience;experimental study;Head;Health;hippocampal pyramidal neuron;Hippocampus;Image;In Vitro;in vivo;in vivo two-photon imaging;Individual;insight;Learning;Locomotion;Mediating;member;Memory;Memory Disorders;Memory impairment;memory process;memory retention;Molecular;Motivation;Mus;Muscarinic Acetylcholine Receptor;Muscarinics;Nature;nerve supply;Neurodegenerative Disorders;neuronal excitability;Neurons;Neuropharmacology;neuroregulation;novel;Outcome;Output;Pattern;Physiological;Play;Population;receptor;response;Rodent;Role;Sensory;Shapes;Signal Transduction;spatial memory;Specificity;Synapses;Synaptic plasticity;Task Performances;Theoretical model;tool;Training;Visit

PROJECT_TITLE: CRCNS: Role of mAChRs on CA 1 pyramidal neurons in memory formation and stability

STUDY_SECTION_NAME: Special Emphasis Panel[ZRG1-BN-P(50)R]


ADMINISTERING_IC: NS

IC_NAME: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

NIH_SPENDING_CATS: Bioengineering;Networking and Information Technology R&D (NITRD);Neurosciences

ORG_CITY: MELBOURNE

ORG_COUNTRY: AUSTRALIA

ORG_FIPS: AS

ORG_NAME: UNIVERSITY OF MELBOURNE

PHR: Project Narrative Humans and other animals are constantly perceiving and interpreting events from their surroundings and using this information to choose appropriate behaviors. Exactly how the brain's neurons process sensory information and integrate information from different senses, however, remains unclear. Our work involves monitoring all of the brain's neurons simultaneously while the senses are stimulated, providing detailed and complete maps of the circuits that detect, process, and integrate sensory information.

PI_NAMEs: SCOTT, ETHAN KIME (contact)

PROGRAM_OFFICER_NAME: DAVID, KAREN KATE

PROJECT_TERMS: 3-Dimensional;Address;Afferent Neurons;Animals;Architecture;Auditory;auditory stimulus;autism spectrum disorder;Behavior;Biological;Biological Models;Biology;Brain;Brain region;calcium indicator;Categories;cell type;Cells;Complex;Computational Biology;computational network modeling;computational neuroscience;Computer Models;connectome;Data;data modeling;design;detector;Discipline;Disease;Elements;Environment;Event;Evolution;experience;experimental study;Forms Controls;Functional Imaging;Future;generative models;Genes;Goals;Graph;Hearing;Holography;Human;Image;imaging system;Individual;innovation;insight;interdisciplinary approach;Knowledge;Light;Lighting;Link;Maps;mathematical model;Mathematics;Mental disorders;Microscopy;Mind;Modality;Modeling;Monitor;Morphology;Natural History;network models;neural;Neurons;Neurosciences;Neurotransmitters;novel strategies;optic trap;optical traps;Optics;optogenetics;Outcome;Pattern;Perception;Phenotype;Physics;Process;Quality of life;Reporting;Research;Resolution;response;Role;Sampling;Sensory;sensory integration;Sensory Process;sensory system;Shapes;Stimulus;Techniques;Testing;Theoretical model;Time;Tissues;Touch sensation;Vision;Visual;visual processing;visual stimulus;Work;Zebrafish

PROJECT_TITLE: An integrated platform for studying sensory networks in the vertebrate brain


ADMINISTERING_IC: HL

ED_INST_TYPE: SCHOOLS OF PUBLIC HEALTH

IC_NAME: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

NIH_SPENDING_CATS: Clinical Research;Clinical Trials and Supportive Activities;Dissemination and Implementation Research;Health Services;Hematology;Prevention;Rare Diseases;Sickle Cell Disease

ORG_CITY: NEW YORK

ORG_DEPT: PUBLIC HEALTH & PREV MEDICINE

ORG_NAME: NEW YORK UNIVERSITY

ORG_STATE: NY

PHR: Project Narrative Hydroxyurea (HU) is underutilized in low- and middle-income countries (LMIC) like Nigeria due to barriers of adoption at the provider level. Using a mixed-methods implementation design, we will conduct our study in four sequential phases: Based on the Exploration, Preparation, Implementation, and Sustainment (EPIS) framework, and determine the inner organizational context, outer context, and implementation processes likely to influence SIM (Screen, Initiate, and Maintain) adoption of HU by providers at SPARC-NEt clinical sites to improve health outcomes for patients with SCD using the evidence-based TASSH TCP implementation strategy. The findings of this study have the potential to identify effective strategies for improving the management of SCD in Nigeria and other LMIC.

PI_NAMEs: NNODU, OBIAGELI EUNICE;PEPRAH, EMMANUEL K (contact)

PROGRAM_OFFICER_NAME: HAILU, BENYAM

PROJECT_TERMS: Address;Adopted;Adoption;adverse outcome;Africa;African;Algorithms;Birth;Blood Transfusion;Caring;Cephalic;Clinical;clinical research site;clinical training;Clinical Trials;Consultations;control trial;Counseling;Country;Disease;Disease Management;dosage;Education;Educational workshop;Effectiveness;effectiveness evaluation;Ensure;evidence base;Exploration, Preparation, Implementation, and Sustainment;Feedback;Focus Groups;follow-up;Funding;Ghana;Government;Guidelines;Health;health care service organization;Health education;Health Personnel;health training;Healthcare;Hematologist;Hemoglobinopathies;Hydration status;hydroxyurea;hypertension control;implementation barriers;implementation design;implementation facilitation;implementation fidelity;implementation process;implementation strategy;improved;Infection;Infrastructure;Intervention;Interview;Ions;Knowledge;low and middle-income countries;Mediator;Medicine;Methods;mortality;Neonatal Screening;Nigeria;Nigerian;Nurses;nutrition;patient oriented;patient screening;Patient-Focused Outcomes;Patients;Persons;Phase;Physicians;Policies;Preparation;primary outcome;Prophylactic treatment;Protocols documentation;Provider;provider adoption;provider-level barriers;Public Health;Published Comment;Randomized;Research Design;Resource-limited setting;scale up;screening;secondary outcome;Sickle Cell Anemia;Specialist;Structure;System;systematic review;tailored health care;Time;tool;Training;United States National Institutes of Health

PROJECT_TITLE: mAnaging siCkle CELl disease through incReased AdopTion of hydroxyurEa in Nigeria (ACCELERATE)

STUDY_SECTION: HSQE

STUDY_SECTION_NAME: Health Services: Quality and Effectiveness Study Section[HSQE]


NIH_SPENDING_CATS: Biotechnology;Neurosciences;Regenerative Medicine;Stem Cell Research;Stem Cell Research - Nonembryonic - Human;Transplantation

ORG_CITY: BALTIMORE

ORG_DEPT: NEUROSURGERY

ORG_NAME: UNIVERSITY OF MARYLAND BALTIMORE

ORG_STATE: MD

PHR: Project Narrative This project exploits a technology platform that modulates the activities and functions of neural stem cells by biochemically engineering their cell surface carbohydrates. We apply this “metabolic glycoengineering” strategy to promote neural regeneration to heal brain injury in a rodent model and investigate the mechanistic basis of the anticipated healing effects.

PI_NAMEs: JIA, XIAOFENG  (contact)

PROGRAM_OFFICER_NAME: LAVAUTE, TIMOTHY M

PROJECT_TERMS: Adhesions;Affinity;analog;Animal Model;Animals;Apoptosis;Behavior assessment;Behavioral;Biochemical;Biological;Biological Process;Biology;Brain;Brain Injuries;Cadherins;Carbohydrates;Cell Adhesion;Cell Communication;cell motility;Cell surface;Cells;Cellular biology;Central Nervous System Diseases;Chemical Structure;Chemicals;Chemistry;clinical application;clinical translation;Complex;conventional therapy;cost effectiveness;covalent bond;design;Development;Dose;drug candidate;Electrophysiology (science);embryo cell;Engineering;Event;extracellular;Extracellular Matrix;Foundations;functional group;functional improvement;Generations;Glycoconjugates;Glycoengineering;glycoproteomics;Gold;healing;Healthcare;Heart Arrest;Human;immune cell infiltrate;Implant;improved;In Vitro;in vivo;injured;injury recovery;innovation;intercellular communication;Intercept;Ischemia;Kinetics;Lead;Malignant Neoplasms;Mass Spectrum Analysis;Mediator;Metabolic;Metabolism;Methodology;migration;Modeling;Monosaccharides;Motility;N-acetylmannosamine;Nature;Nerve Regeneration;nerve stem cell;neural;Neurites;Neuronal Differentiation;Neurons;Neurophysiology - biologic function;neuroregulation;novel;Organism;Pathway interactions;Pharmaceutical Preparations;Physiological;Polysaccharides;Preclinical Testing;Proteins;Rattus;receptor;Recovery;Recovery of Function;Reporting;response;Rodent Model;Safety;scaffold;Sialic Acids;Signal Transduction;Spatial Distribution;stem cell biology;stem cell differentiation;stem cell fate;stem cell therapy;Stimulus;Structure-Activity Relationship;Sulfhydryl Compounds;Surface;Synaptic plasticity;Techniques;technology platform;Testing;Therapeutic;therapeutic candidate;Time;Tissues;translational approach;Translations;Transplantation;Wnt proteins;WNT Signaling Pathway;Work

PROJECT_TITLE: Improving Brain Recovery Through Glycoengineering

STUDY_SECTION: BMBI

STUDY_SECTION_NAME: Biomaterials and Biointerfaces Study Section[BMBI]


ADMINISTERING_IC: DK

FUNDING_MECHANISM: TRAINING, INDIVIDUAL

IC_NAME: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES

NIH_SPENDING_CATS: Clinical Research;Diabetes;Genetics

ORG_NAME: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

PHR: PROJECT NARRATIVE Diabetes is a worsening health epidemic, incurring significant medical and societal costs. In this proposal, we will investigate rare variations in Maturity Onset Diabetes of the Young (MODY) genes in the multi-ethnic Mount Sinai BioMe Biobank and the UK Biobank, with the goal of identifying novel associations to type 2 diabetes and MODY. The results will help inform diabetes prevention, diagnosis, and management, ultimately leading to improved personalized diabetes care in multi-ethnic populations.

PI_NAMEs: STALBOW, LAUREN  (contact)

PROGRAM_OFFICER_NAME: CASTLE, ARTHUR

PROJECT_TERMS: access disparities;Address;Affect;Age of Onset;American;Antibodies;Autoimmunity;biobank;Caring;Clinic;Clinical;clinical care;clinical phenotype;Data;design;Development;Diabetes Mellitus;diabetes mellitus genetics;Diabetes prevention;diabetes risk;Diagnosis;Diagnostic;Disease;Disease Management;early onset;Epidemic;Ethnic Population;European ancestry;Family;Family history of;Functional impairment;Gene Mutation;General Population;Genes;Genetic Research;Genetic study;genetic testing;Genetic Variation;Genotype;Goals;Health;improved;Individual;individualized prevention;Knowledge;Medical Care Costs;Medicine;multi-ethnic;Mutate;Mutation;Non-Insulin-Dependent Diabetes Mellitus;novel;Pancreas;Patients;Penetrance;phenome;Phenotype;Physicians;Population;population based;Predisposition;Prevalence;Rare Diseases;rare variant;Research;Risk;Scientist;societal costs;Structure of beta Cell of islet;Symptoms;Therapeutic;Time;trait;type I and type II diabetes;United States;Variant

PROJECT_TITLE: A genotype first approach to studying diabetes


ADMINISTERING_IC: EY

IC_NAME: NATIONAL EYE INSTITUTE

NIH_SPENDING_CATS: Aging;Eye Disease and Disorders of Vision;Neurodegenerative;Neurosciences

ORG_CITY: IRVINE

ORG_DEPT: OPHTHALMOLOGY

ORG_NAME: UNIVERSITY OF CALIFORNIA-IRVINE

ORG_STATE: CA

PHR: PROJECT NARRATIVE The successful completion of this project will lead to insights into molecular pathways that cause trabecular meshwork dysfunction and elevation of intraocular pressure in glaucoma, a leading cause of irreversible vision loss. Furthermore, our proposed studies will target these pathological mechanisms for the treatment of glaucoma.

PI_NAMEs: SONKUSARE, SWAPNIL K.;ZODE, GULAB  (contact)

PROGRAM_OFFICER_NAME: SONG, HONGMAN

PROJECT_TERMS: Aqueous Humor;aqueous humor flow;Blindness;Cell model;Cells;Chemicals;Chronic;Electrophysiology (science);endoplasmic reticulum stress;Enzymes;ex vivo perfusion;Eye;Functional disorder;Genetic;Glaucoma;Goals;Homeostasis;Human;human model;Image;Impairment;improved;inhibitor;innovation;insight;Ion Channel;knock-down;Laboratories;Measurement;Molecular;mouse model;Mus;Nitric Oxide;Nitric Oxide Synthase;NOS2A gene;NOS3 gene;novel;Ocular Hypertension;Open-Angle Glaucoma;overexpression;Oxidants;Oxidation-Reduction;Oxidative Stress;patch clamp;Pathologic;Pathology;Pathway interactions;Perfusion;Peroxonitrite;pharmacologic;Physiologic Intraocular Pressure;Post-Translational Protein Processing;Primary Open Angle Glaucoma;receptor;Research;Resistance;Risk Factors;Signal Pathway;Signal Transduction;Techniques;therapeutic target;Tissues;Trabecular meshwork structure;transcription factor;Vanilloid

PROJECT_TITLE: Impaired TRVP4-eNOS signaling in TM contributes to glaucoma

STUDY_SECTION_NAME: Pathophysiology of Eye Disease - 2 Study Section[PED2]


ADMINISTERING_IC: AI

FUNDING_MECHANISM: OTHER RESEARCH-RELATED

IC_NAME: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

NIH_SPENDING_CATS: Infectious Diseases

ORG_CITY: East Greenwich

ORG_NAME: GORDON RESEARCH CONFERENCES

ORG_STATE: RI

PHR: Project Narrative Parasitic infections inflict a tremendous toll on human health, both nationally and globally. The Gordon Research Conference on Host-Parasite Interactions is the most prominent venue for scientific exchange at the leading edge of modern parasitology research. The 2024 conference provides scientists with the opportunity to gain an overview of the entire field, to learn about the most recent and most exciting advances, and to discuss and set the national and global research agenda for the future.

PI_NAMEs: WARD, GARY E (contact)

PROGRAM_OFFICER_NAME: STRICKLER-DINGLASAN, PATRICIA M

PROJECT_TITLE: 2024 Biology of Host-Parasite Interactions Gordon Research Conference and Gordon Research Seminar

STUDY_SECTION_NAME: Special Emphasis Panel[ZAI1 LK-D (J1)]


NIH_SPENDING_CATS: Biodefense and Related Countermeasures;Disability Research;Emerging Infectious Diseases;Infectious Diseases;Prevention;Rare Diseases;Tickborne Diseases;Vector-Borne Diseases

ORG_CITY: OMAHA

ORG_DEPT: PATHOLOGY

ORG_NAME: UNIVERSITY OF NEBRASKA MEDICAL CENTER

ORG_STATE: NE

PHR: Project Narrative The Annual Meeting of the American Society for Rickettsiology assembles clinicians, researchers, and public health scientists whose interests center on Rickettsia bacteria, a significant cause of human disease, to drive collaborative multidisciplinary research in a diverse, equitable, respectful and inclusive scientific environment.

PI_NAMEs: GILK, STACEY D (contact)

PROGRAM_OFFICER_NAME: MULACH, BARBARA L

PROJECT_TERMS: Academia;accurate diagnosis;Address;Advertisements;American;Anaplasma;Antibiotics;Arthropod Vectors;Arthropods;Award;Awareness;Bacteria;Biology;career;career development;Charge;Child;Child Care;Classification;climate change;Collaborations;Communicable Diseases;Communities;Congresses;cost;Coxiella burnetii;Diagnosis;disability;Disabled Persons;Disease;early-career faculty;Ecology;Ehrlichia;Endemic Diseases;endosymbiont;Environment;Epidemiology;Equilibrium;Equity;equity, diversity, and inclusion;Family;family support;Financial Support;First Generation College Students;fitness;Fleas;Fostering;Genetic;Government;Health;Healthcare;Hemorrhage;Home;Human;human disease;human morbidity;human mortality;Immunology;Impairment;Infection;Insecta;Interdisciplinary Study;interest;International;Laboratories;lecturer;lectures;Lice;Life;Location;meetings;member;Microbe;Microbiology;Minority;Mission;Morbidity - disease rate;mortality;National Institute of Allergy and Infectious Disease;Nematoda;Neurologic;nonbinary;Oral;Organ;originality;Participant;pathogen;Pattern;Postdoctoral Fellow;posters;prevent;Prevention;Prevention strategy;Private Sector;Production;programs;Public Health;Q Fever;Readiness;Regional Disease;Research;research and development;Research Personnel;Research Support;Resort;Resources;response;Rickettsia;Rickettsia Infections;Rocky Mountain Spotted Fever;Schedule;Scientist;Services;Severities;Sex Differentiation;social media;Societies;Spain;Students;surveillance strategy;symposium;Symptoms;technology development;Tick-Borne Diseases;Ticks;transmission process;Travel;treatment strategy;Typhus;Underrepresented Populations;United States;United States Dept. of Health and Human Services;Universities;Urbanization;Vaccines;vector;Vector-transmitted infectious disease;Virginia;web site;Wolbachia;Woman;Work;working group

PROJECT_TITLE: Annual meeting of the American Society for Rickettsiology


ADMINISTERING_IC: DA

ED_INST_TYPE: SCHOOLS OF ARTS AND SCIENCES

IC_NAME: NATIONAL INSTITUTE ON DRUG ABUSE

NIH_SPENDING_CATS: Bioengineering;Biotechnology;Drug Abuse (NIDA only);Gene Therapy;Genetics;HIV/AIDS;Infectious Diseases;Regenerative Medicine;Stem Cell Research;Stem Cell Research - Nonembryonic - Human;Stem Cell Research - Umbilical Cord Blood/ Placenta;Stem Cell Research - Umbilical Cord Blood/ Placenta - Human;Substance Misuse

ORG_CITY: WASHINGTON

ORG_DEPT: BIOLOGY

ORG_NAME: CATHOLIC UNIVERSITY OF AMERICA

ORG_STATE: DC

PHR: PROJECT NARRATIVE More than 40 million people across the globe are now living with HIV-1, of which the substance users constitute a disproportionate and “key population”, yet there is no cure or vaccine on the horizon. Using our recently developed bacteriophage T4 artificial virus vector technology, this proposal will establish a novel and affordable in vivo HIV cure platform that can be easily administered to substance users through one or two infusions. The HIV cure “drug” will target stem cells and introduce genetic modifications that confer resistance to HIV infection and then, by repopulating the body with HIV-resistant blood cells including resistant T cells, it replaces the HIV reservoir and leads to functional HIV cure.

PI_NAMEs: RAO, VENIGALLA B. (contact)

PROGRAM_OFFICER_NAME: BORGMANN, KATHLEEN RUTH

PROJECT_TERMS: Adherence;Affect;Affinity;Anti-retroviral drug resistance;Bacteriophage T4;Bacteriophages;Binding;Blood;Blood Cells;Capsid;Categories;CCR5 gene;CD4 Positive T Lymphocytes;Cells;Cord Blood Hematopoietic stem cells;Deletion Mutation;delivery vehicle;Disease;DNA;DNA Packaging;Dose;Drug Modelings;Engineering;Enzymes;Event;Exhibits;Fiber;flexibility;Future;gene therapy;gene-targeted therapy;Genetic;Genome;genome editing;Guide RNA;Health;Hematopoietic Stem Cell Mobilization;Hematopoietic Stem Cell Transplantation;Hematopoietic stem cells;High Prevalence;HIV;HIV Infections;HIV resistance;HIV-1;Hour;Human;human stem cells;Immune response;in vivo;in vivo evaluation;Infusion procedures;Libraries;Ligands;Lipids;Malignant Neoplasms;Mental Health;Modification;mouse model;Mutation;nanobodies;nanoparticle;Nerve Degeneration;novel;Outpatients;particle;Patients;Persons;Pharmaceutical Preparations;Play;Population;precision medicine;Protocols documentation;Receptor Gene;reconstitution;Resistance;Specificity;stem cell model;stem cells;substance user;T-Lymphocyte;Technology;Testing;transmission process;Tube;Umbilical Cord Blood;Vaccines;vector;Viral Vector;Virus

PROJECT_TITLE: Engineering Bacteriophage T4 as a Targeted Gene Therapy Drug for in vivo HIV Cure

STUDY_SECTION_NAME: Special Emphasis Panel[ZDA1 SKP-X (J1)]


ORG_CITY: MILWAUKEE

ORG_DEPT: INTERNAL MEDICINE/MEDICINE

ORG_NAME: MEDICAL COLLEGE OF WISCONSIN

ORG_STATE: WI

PHR: PROJECT NARRATIVE The field of lipoprotein metabolism remains one of the most dynamic areas in biomedical sciences for both basic scientific inquiry and translational research, especially given the role of lipoproteins in modulating risk of cardiovascular disease and other metabolic disorders. The 2024 Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) on Lipoprotein Metabolism will feature emerging themes and cutting-edge concepts that can ultimately be translated into clinical benefit for the millions of patients whose risk of lipoprotein- associated cardiovascular disease cannot be adequately addressed by existing therapeutic strategies. The GRC and GRS – both premier, multidisciplinary scientific meetings – will provide a unique forum in which diverse scientists spanning from trainees to established investigators can enrich their knowledge base, engage in new collaborations, network, and advance the field of lipoprotein metabolism.

PI_NAMEs: SAHOO, DAISY  (contact)

PROGRAM_OFFICER_NAME: PLAYFORD, MARTIN P

PROJECT_TERMS: Address;Area;Basic Science;Bioinformatics;Biological;Biological Models;Breathing;Cardiovascular Diseases;cardiovascular disorder risk;career;Cells;Cessation of life;Child Care;Chronic Disease;Clinical;Collaborations;Color;combat;Communication;design;Development;Diabetes Mellitus;disability;Disabled Persons;Discipline;diversity and inclusion;Ensure;Environment;ethnic minority;experience;Faculty;Fostering;fundamental research;genome sciences;Geographic Locations;Goals;graduate student;Health;Hour;Human;improved;Individual;inhibitor;innovation;interest;International;Interpersonal Relations;Knowledge;knowledge base;Length;lipid metabolism;lipidomics;Lipoproteins;meetings;member;Mentorship;metabolic abnormality assessment;Metabolic Diseases;Metabolism;Molecular;Morbidity - disease rate;mortality;multidisciplinary;Nationalities;Nervous System Disorder;new therapeutic target;novel therapeutic intervention;novel therapeutics;Obesity;Oral;Participant;Pathogenesis;Patients;peer;Policies;Postdoctoral Fellow;posters;preclinical study;programs;Proteomics;Public Health;racial discrimination;racial minority;Research;Research Personnel;Resort;Risk;Role;Schedule;Science;Scientific Inquiry;Scientist;sex;social;success;symposium;System;Systems Biology;Technology;Therapeutic;Time;Translating;Translational Research;Translations;Underrepresented Populations;United States National Institutes of Health;Woman

PROJECT_TITLE: 2024 Gordon Research Conference and Gordon Research Seminars on Lipoprotein Metabolism

STUDY_SECTION_NAME: Special Emphasis Panel[ZHL1 CSR-L (J2)]


ADMINISTERING_IC: MH

IC_NAME: NATIONAL INSTITUTE OF MENTAL HEALTH

NIH_SPENDING_CATS: Anxiety Disorders;Brain Disorders;Mental Health;Mental Illness;Serious Mental Illness

ORG_CITY: CHAPEL HILL

ORG_DEPT: GENETICS

ORG_NAME: UNIV OF NORTH CAROLINA CHAPEL HILL

ORG_STATE: NC

PHR: PROJECT NARRATIVE The existing research on obsessive-compulsive disorder (OCD) is heavily focused on individuals of European ancestry and performed by researchers who are also primarily of European descent. In this project, we request funds to provide travel awards for underrepresented minority (URM) trainees to attend a conference specifically focused on OCD in Latin America. The conference will feature career development and mentoring sessions designed to increase the representation of URM trainees.

PI_NAMEs: CROWLEY, JAMES JOSEPH (contact)

PROGRAM_OFFICER_NAME: MEZA-CERVERA, TATIANA

PROJECT_TERMS: American Indians;Argentina;Award;bilingualism;Biomedical Research;Black race;Bolivia;Canada;career development;Case Study;Categories;Chile;Collaborations;Colombia;Communication;Communities;Congresses;design;Disabled Persons;disadvantaged background;Environment;Ethics;Etiology;European;European ancestry;Evidence based treatment;Faculty;Family;Fostering;Funding;Funding Opportunities;Genetic;genome wide association study;Genomics;Goals;Health Professional;Honduras;Hybrids;improved;Individual;Institution;interest;Knowledge;Language;Latin America;Latin American;Latinx;meetings;Mental disorders;Mental Health;Mentors;Mexico;minority trainee;National Institute of Mental Health;Nature;next generation;Nonprofit Organizations;Obsessive-Compulsive Disorder;Paraguay;Participant;Patients;Persons;Peru;Phenotype;Portuguese;Postdoctoral Fellow;Productivity;psychoeducation;Publishing;Research;Research Personnel;Resource Development;Science;Services;Site;Spanish;Students;success;symposium;synergism;Training;Translations;Travel;Underrepresented Minority;underrepresented minority student;Underrepresented Populations;United States National Institutes of Health;virtual

PROJECT_TITLE: Annual Latin American Congress on OCD

STUDY_SECTION_NAME: Special Emphasis Panel[ZMH1 ERB-G (G2)]


ED_INST_TYPE: ORGANIZED RESEARCH UNITS

NIH_SPENDING_CATS: Neurosciences

ORG_NAME: ADVANCED SCIENCE RESEARCH CENTER

PHR: Project Narrative Disruption of biological timekeeping is known to contribute to a range of disorders and the biomarkers used to diagnose disease and the effectiveness of treatment are strongly influenced by biological clocks. The 2024 Society for Research on Biological rhythms Meeting will bring together scientists from a wide range of fields, working on a diversity of model systems and at many different levels of biological organization. The goals of this meeting are to: (a) feature the latest research findings and methodological advances in the field; (b) showcase the emergence of Circadian Medicine; (c) support the professional development of trainees and junior faculty; and (d) broaden participation in the field of biological rhythms.

PI_NAMEs: SHAFER, ORIE T (contact)

PROGRAM_OFFICER_NAME: HE, JANET

PROJECT_TERMS: analytical method;Award;Basic Science;Behavior;Biological;Biological Clocks;Biological Markers;Biological Models;Biological Rhythm;broadening participation research;Cells;Chronobiology;circadian;Circadian Rhythms;Clinic;clinical practice;cost;design;Development;Diagnosis;Disease;disease diagnosis;Educational workshop;Event;Faculty;Faculty Workshop;Fees;Fellowship;Funding;Goals;Grant;Health;Human;Incentives;insight;Investigation;Knowledge;lectures;Low income;Medicine;meetings;Mentorship;Metabolism;Methodology;Mission;next generation;Nurses;Organism;Patients;Pharmacists;Physicians;Physiology;Postdoctoral Fellow;posters;prevent;programs;Puerto Rico;Research;Research Personnel;Scientist;Slide;Societies;Students;support network;symposium;Technology;Time;Training;Translational Research;Travel;Treatment Effectiveness;Underrepresented Minority;Work

PROJECT_TITLE: The Society for Research on Biological Rhythms Conference: Rhythms from Cell to Clinic

STUDY_SECTION_NAME: Special Emphasis Panel[ZNS1 SRB-K (43)]


ADMINISTERING_IC: CA

ED_INST_TYPE: SCHOOLS OF VETERINARY MEDICINE

IC_NAME: NATIONAL CANCER INSTITUTE

NIH_SPENDING_CATS: Biotechnology;Cancer

ORG_CITY: MADISON

ORG_NAME: UNIVERSITY OF WISCONSIN-MADISON

PHR: PROJECT NARRATIVE The non-malignant stroma cells and extracellular matrix surrounding the tumor are essential for tumor progression and drug resistance. The meeting in Madison, WI will bring together clinical and laboratory-based scientists and trainees across the Midwest states to discuss their research progress and identify the critical challenges and emerging opportunities in the field. The primary objective is to foster collaborations among established scientists, early-stage investigators, and trainees and support the training of the next generation of scientists for careers focused on the tumor microenvironment.

PI_NAMEs: ARENDT, LISA M (contact);PONIK, SUZANNE MARIE

PROGRAM_OFFICER_NAME: GEORGE, CHRISTINA DAWN

PROJECT_TERMS: Acceleration;Affect;Angiogenesis Inhibitors;Award;Biocompatible Materials;Biomimetics;Cancer Biology;cancer cell;cancer research center director;career;career development;Career Mobility;career networking;cell stroma;Cells;Child Care;Clinical;Collaborations;Communication;Communities;cost;Cues;Data;design;Development;Disabled Persons;Discipline;Disease;Doctor of Philosophy;Doctor of Veterinary Medicine;Drug resistance;Education;Emerging Technologies;Ensure;ethnic minority;Event;experience;Extracellular Matrix;Faculty;Fostering;Funding;Future;Gender;Geography;Glioblastoma;Goals;graduate student;Grant;Growth;Illinois;Immune checkpoint inhibitor;Immune system;Indiana;Individual;International;Iowa;Kansas;knowledge base;Laboratories;Leadership;Learning;Malignant Neoplasms;meetings;member;Mentors;Michigan;Midwestern United States;Minnesota;Missouri;Modeling;multidisciplinary;Natural regeneration;Nebraska;next generation;Non-Malignant;Oral;Participant;Patient Recruitments;Postdoctoral Fellow;posters;programs;racial minority;Research;Research Personnel;Resistance;response;Role;Science;Scientist;skills;Source;symposium;targeted cancer therapy;Technology;Therapeutic;Thinking;Training;Training Support;Translational Research;Travel;treatment response;tumor;tumor growth;tumor microenvironment;tumor progression;Tumor Promotion;tumorigenesis;Universities;Wisconsin;Work

PROJECT_TITLE: The Midwest Tumor Microenvironment Meeting

STUDY_SECTION_NAME: Special Emphasis Panel[ZCA1 PCRB-9 (J1)]


ORG_CITY: HOUSTON

ORG_DEPT: PEDIATRICS

ORG_NAME: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

ORG_STATE: TX

PHR: Public Health Relevance The 7th International Enteric Nervous System Development Meeting: Connection, Cross-talk and Collaboration brings together cutting edge bench scientific research with current bedside clinical management, and includes a diverse group of geneticists, molecular and cellular biologists, physiologists, pathologists, physicians (gastroenterologists and surgeons), and stem cell researchers, who all share a common interest in the development and function of the enteric nervous system (ENS) as well as the treatment of neurointestinal diseases. A major goal of this conference grant is to increase the participation of young investigators, especially from groups traditionally under-represented in science such as women and minorities. This grant will support Travel Awards and Scientific Merit Awards for these bright young scientists and foster mentoring relationships that will give them invaluable opportunities and improve their likelihood of future success.

PI_NAMEs: SPEER, ALLISON LEIGH (contact)

PROGRAM_OFFICER_NAME: SHEA-DONOHUE, TEREZ

PROJECT_TERMS: Award;Behavior;bench to bedside;Boston;career;Cells;Cellular biology;Clinical Management;Collaborations;Congenital Megacolon;Constipation;cost;Country;COVID-19 pandemic;Data;Development;Discipline;Disease;Economically Deprived Population;Enteral;Enteric Nervous System;enteric neuropathy;Faculty;Fostering;Funding;Future;Gastroenterologist;Generations;Genetic;Goals;Grant;Growth;Hong Kong;Image;improved;Individual;Infant;interest;International;K-Series Research Career Programs;Knowledge;London;Manuscripts;meetings;member;Mentors;Mentorship;Minority;Molecular;Molecular Biology;nerve stem cell;nervous system development;Neural Crest;Neurons;Neurotransmitters;New York;Outcome;Participant;Pathologist;Philadelphia;Physicians;Physiology;public health relevance;Publishing;Regenerative Medicine;Research;Research Personnel;Science;Scientific Advances and Accomplishments;Scientist;Signal Pathway;socioeconomic disadvantage;stem cell biology;stem cells;success;Surgeon;symposium;synergism;Systems Biology;Systems Development;systems research;Transcriptional Regulation;Travel;Underrepresented Populations;United States National Institutes of Health;Woman

STUDY_SECTION_NAME: Special Emphasis Panel[ZDK1 GRB-7 (J3)]


NIH_SPENDING_CATS: Cancer;Precision Medicine

ORG_CITY: Rockville

ORG_NAME: FEDERATION OF AMER SOC FOR EXPER BIOLOGY

PHR: PROJECT NARRATIVE This application requests partial support for the 2024 FASEB Summer Research Conference on Cell Signaling in Cancer: from Mechanisms to Therapy, which is focused on the genetic, molecular, and biochemical mechanisms of cellular signal transduction in malignant transformation and proof-of-concept or clinically tractable means to translate these discoveries. Both basic/translational scientists and clinicians at this conference will be exposed to the emerging concepts in the cancer cell signaling field, including but not limited to including but not limited to Structure and Function of Signaling Complexes, Signaling in Space and Time in Cancer, Systems Biology and Proteomics, Nutrient Signaling and Metabolic Processes, Tumor Microenvironment, Modeling of Cancer and Chemical Biology. Together, participants will be encouraged to explore deeper mechanistic understanding of the contribution of dysfunctional cellular signaling networks to tumor initiation and progression, which was critical for the translation of drugs used clinically today, with the long-term goal of bringing precision medicine to cancer patients.

PI_NAMEs: LEE, MICHAEL JUNGHO (contact)

PROGRAM_OFFICER_NAME: LUO, RUIBAI

PROJECT_TERMS: Academia;Achievement;angiogenesis;Award;bcr-abl Fusion Proteins;bench to bedside;Biochemical;Biological Process;Biology;BRAF gene;cancer cell;cancer genomics;Cancer Model;Cancer Patient;cancer therapy;career;Cell Death;Cell division;cell growth;Cell Physiology;Cell Survival;Characteristics;Chemicals;Chromosomal translocation;Clinic;Clinical;Clinical Sciences;Collaborations;combat;Communication;Communities;Complex;Cues;Dependence;Discipline;Disease;DNA Sequence Alteration;Drug Industry;Drug usage;Educational workshop;Environment;ERBB2 gene;experience;Exposure to;FDA approved;Financial Support;functional genomics;Future;Genetic;Goals;Growth;Heterogeneity;Human;Industry;Invaded;Investments;kinase inhibitor;Knowledge;Malignant - descriptor;Malignant Neoplasms;MAP2K1 gene;Maps;meetings;Melanoma;Metabolism;Methodology;migration;Molecular;Monitor;mutant;Mutation;Neoplasm Metastasis;neoplastic cell;NF1 gene;novel strategies;novel therapeutics;Nutrient;nutrient metabolism;Oncogenes;Oncogenic;Oncoproteins;Outcome;Output;Participant;Pathway interactions;Patients;Pharmaceutical Preparations;Phosphotransferases;Physiology;PIK3CA gene;posters;precision medicine;Process;Productivity;Progression-Free Survivals;Proliferating;Proteins;Proteomics;PTPN11 gene;Request for Applications;Research;Research Personnel;Resistance;response;Scientist;Senior Scientist;Series;Signal Pathway;Signal Transduction;small molecule;small molecule inhibitor;structural biology;Structure;success;summer research;Survival Rate;symposium;Systems Biology;targeted treatment;Technology;Therapeutic;therapeutic target;Time;Toxic effect;Training;Transducers;Translating;translational physician;Translational Research;translational scientist;Translations;Travel;tumor;tumor initiation;tumor microenvironment;tumor progression;Tumor Suppressor Proteins;Tumor-Associated Process;tumorigenesis;Unresectable;Work

PROJECT_TITLE: Cell Signaling in Cancer- From Mechanisms to Therapy


NIH_SPENDING_CATS: Biodefense and Related Countermeasures

ORG_CITY: BOSTON

ORG_NAME: BRIGHAM AND WOMEN'S HOSPITAL

PHR: Narrative Protecting our nation from chemical threats, whether industrial or existential, is the central mission of the NIH CounterACT Network, and this Annual Symposium is the main venue for the presentation of exciting new science and for the exchange of ideas across the network. The Symposium is also designed to allow the incorporation of new ideas from outside the current countermeasure community to help accelerate the program’s ability to address current threats and to lay the groundwork for identifying and interdicting emerging and future threats. Enlarging, and maintaining this particular community, as well as innovating across the field, are vital components of the mission of this 17th Annual CounterACT Network Symposium.

PI_NAMEs: MACRAE, CALUM A. (contact);PETERSON, RANDALL T

PROGRAM_OFFICER_NAME: SPRIGGS, SHARDELL M

PROJECT_TERMS: Acceleration;Address;Alcohols;Area;Award;Biology;chemical countermeasure;chemical threat;Cities;Clinical;clinically relevant;cohort;Communities;Dedications;design;Development;Education;Environment;environmental chemical;Event;Feedback;Funding;Future;Generations;graduate student;Growth;human morbidity;human mortality;Individual;Industrialization;innovation;interest;International;meetings;member;Mission;Museums;Natural History;Nature;novel;Participant;Phase;post implementation;Postdoctoral Fellow;posters;Productivity;programs;Research;Research Personnel;Research Project Grants;Science;Scientist;social;Sodium Chloride;Source;symposium;Toxicant exposure;translational pipeline;Translations;Travel;United States National Institutes of Health;Utah;Work

PROJECT_TITLE: 17th Annual Counteract Network Symposium


ORG_CITY: EUGENE

ORG_DEPT: NEUROSCIENCES

ORG_NAME: UNIVERSITY OF OREGON

ORG_STATE: OR

PHR: Narrative Major advances in neuroscience have arisen through studies of diverse species with different brain organization, including invertebrates (e.g. nematodes, fruitfly) and vertebrates (e.g. fish, rodents, primates). Cephalopods represent the largest brains in the animal kingdom outside of vertebrates, but have been under-studied due to technical limitations. Several recent advances have accelerated the pace of research in cephalopod neuroscience over the past few years, and the proposed meeting will be the first ever to bring together this emerging and rapidly growing community.

PI_NAMEs: ALBERTIN, CAROLINE B;CROOK, ROBYN ;KATZ, PAUL S;NIELL, CRISTOPHER M (contact)

PROGRAM_OFFICER_NAME: OSBORNE, LESLIE CAROL

PROJECT_TITLE: Cephalopod Neuroscience Conference


ADMINISTERING_IC: OH

IC_NAME: NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH

ORG_CITY: GAINESVILLE

ORG_DEPT: MISCELLANEOUS

ORG_NAME: UNIVERSITY OF FLORIDA

PHR: The goal of the proposed State of the Science Meeting Series: Health and Safety of Gulf Coast and U.S. Caribbean Fishers is to disseminate unique occupational safety and health management strategies to benefit commercial and artisanal fishermen in the coastal Gulf South and the U.S. Caribbean. The State of the Science meeting format will accomplish this through an interdisciplinary network of partners collaborating to share cultural and traditional aspects of the region, contributing climate change and policy factors, and presenting research findings on topics identified as a community burden/need and safety management systems.

PI_NAMEs: AROSEMENA, FARAH ADRIANA (contact);MORIN, ASHLEY MCLEOD

PROGRAM_OFFICER_NAME: CHIOU, SHARON

STUDY_SECTION: SOH

STUDY_SECTION_NAME: Safety and Occupational Health Study Section[SOH]


ADMINISTERING_IC: AT

IC_NAME: NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH

NIH_SPENDING_CATS: Aging;Alcoholism, Alcohol Use and Health;Chronic Pain;Complementary and Integrative Health;Dental, Oral, and Craniofacial Disease;Neurosciences;Pain Research;Substance Misuse

ORG_CITY: ANNAPOLIS

ORG_NAME: UNITED STATES ASSOCIATION FOR THE STUDY OF PAIN, INC.

PHR: Pain continues to be a significant health care problem because of its prevalence, its impact on those who suffer, and the absence of consistently effective therapeutic options devoid of deleterious consequences. To begin to address this problem, the USASP holds an annual scientific meeting that serves to facilitate dialog and interactions between pain scientists, health care providers and patients, disseminate and implement the latest findings, and facilitate the development of the next generation of pain scientists. As the connections made early in a career pay dividends over the long term, support for early career pain investigators is desperately needed to ensure safe and effective pain management in the future.

PI_NAMEs: GOLD, MICHAEL S;NAPADOW, VITALY  (contact)

PROGRAM_OFFICER_NAME: BELFER, INNA

PROJECT_TERMS: Address;Aging;Area;Award;Basic Science;career;career development;Childhood;Clinical;clinical pain;Collaborations;Complex;COVID-19;Data;design;Development;Discipline;Discipline of Nursing;Disparity;Ensure;equity, diversity, and inclusion;experience;Faculty;Fostering;Funding;Future;Generations;Geography;Goals;Group Meetings;Health Personnel;Healthcare;Home;Image;Incidence;innovation;interest;International;Journals;Learning;medical specialties;meetings;member;Mentors;multidisciplinary;next generation;novel;Pain;Pain management;Pain Research;painful neuropathy;Participant;Patients;Persons;Physical therapy;podcast;Policy Maker;Population;posters;Prevalence;Printing;Productivity;programs;psychosocial;Publications;Research;Research Methodology;Research Personnel;Resources;Scholarship;Science;Scientist;Shapes;special interest group;Structure;Students;symposium;therapeutically effective;Time;tool;translational approach;Travel;undergraduate student;United States;United States National Institutes of Health;virtual;Voice

PROJECT_TITLE: US Association for the Study of Pain Annual Scientific Meeting

STUDY_SECTION_NAME: Special Emphasis Panel[ZAT1 AM (04)]


ADMINISTERING_IC: DC

IC_NAME: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

ORG_CITY: BAR HARBOR

ORG_NAME: JACKSON LABORATORY

ORG_STATE: ME

PHR: PROJECT NARRATIVE The “Modeling Hearing and Balance Disorders in Mice: The HEar@JAX Workshop” highlights the unique strengths of the laboratory mouse as a model to study human auditory and vestibular function in health and disease. Animal models are critical to the development of effective new therapeutic approaches for treating hearing loss and balance disorders. Explaining and demonstrating how mice can be used for that goal is also important for the correct public perception of animal research.

PI_NAMEs: TARCHINI, BASILE ROBIN (contact)

PROGRAM_OFFICER_NAME: WATSON, BRACIE

PROJECT_TERMS: Active Learning;Address;Anatomy;Animal Experimentation;Animal Model;Antibiotics;Auditory;Back;Books;Brain Stem;Calcium;California;career;Cells;Cochlea;Collaborations;collaborative environment;college;commune;Communities;Confocal Microscopy;CRISPR/Cas technology;Databases;Defect;Development;Disease;Dissection;Doctor of Medicine;Doctor of Philosophy;Educational process of instructing;Educational workshop;Epithelium;equilibration disorder;Equilibrium;experience;Faculty;Felis catus;Fostering;Future;gene discovery;gene therapy;Gene Transfer;genetic approach;Goals;graduate student;Hair Cells;Hair Dyes;Health;Hearing;hearing impairment;Hearing problem;Hela Cells;Home;Human;human disease;Human Genetics;Image;Instruction;interest;International;Iowa;Knowledge;Laboratories;laboratory curriculum;laboratory experience;Laboratory mice;Labyrinth;lectures;London;Maryland;mechanotransduction;Medical Students;meetings;member;Mentors;Methods;model organism;Modeling;Modernization;mouse genetics;mouse model;Mus;mutant;Mutant Strains Mice;National Institute on Deafness and Other Communication Disorders;Natural regeneration;nerve supply;Noise;novel therapeutic intervention;Organ;Organ Culture Techniques;Otolaryngologist;ototoxicity;Outcome;Paint;Participant;Patients;Perception;Peripheral;Physiological;Postdoctoral Fellow;posters;Presbycusis;Process;Protocols documentation;Qualifying;Recurrence;Research;Research Personnel;residence;Sampling;Schedule;Site;skills;Slide;social;Specimen;symposium;Techniques;Testing;The Jackson Laboratory;Time;Tissues;Training;training opportunity;United States National Institutes of Health;uptake;Vestibular Diseases;Vestibular function;Viral

PROJECT_TITLE: Modeling Hearing and Balance Disorders in Mice: the HEar@JAX Workshop

STUDY_SECTION: CDRC

STUDY_SECTION_NAME: Communication Disorders Review Committee[CDRC]


NIH_SPENDING_CATS: Cancer;Genetics

ORG_CITY: LOUISVILLE

ORG_DEPT: PHARMACOLOGY

ORG_NAME: UNIVERSITY OF LOUISVILLE

ORG_STATE: KY

PHR: Project Narrative DNA damage contributes to the development and progression of chronic human disease including cancer, cardiovascular, neurodegenerative diseases and aging. DNA repair is an essential cellular processes that removes the DNA damage and efficient DNA repair is essential to prevention of these chronic diseases. This symposium will bring together DNA repair researchers to discuss their newest research, to exchange ideas and to develop new collaborations.

PI_NAMEs: STATES, J CHRISTOPHER (contact)

PROGRAM_OFFICER_NAME: SHARMAN, ANU

PROJECT_TERMS: Aging;Anniversary;Cardiovascular Diseases;Cardiovascular system;Cell Physiology;Chronic;Chronic Disease;Collaborations;cost;COVID-19 pandemic;Development;DNA Damage;DNA Repair;Extramural Activities;Fostering;Functional disorder;Funding;genome integrity;Goals;graduate student;Health;Health Sciences;Hereditary Disease;Home;Human;human disease;informal atmosphere;Institution;Link;Maintenance;Malignant Neoplasms;meetings;Michigan;Midwestern United States;Mutagenesis;Nerve Degeneration;Neurodegenerative Disorders;Oral;Participant;peer;Postdoctoral Fellow;posters;Prevention;Recording of previous events;repaired;Research;Research Personnel;Scientist;Secure;Series;Students;success;symposium;Time;Universities;Work

PROJECT_TITLE: 23rd Midwest DNA Repair Symposium


NIH_SPENDING_CATS: Aging;Behavioral and Social Science;Neurosciences

ORG_CITY: BRONX

ORG_NAME: ALBERT EINSTEIN COLLEGE OF MEDICINE

PHR: PI: Buelow, Hannes E. Project narrative The C. elegans Topic Meeting: Neuronal Development, Aging, Synaptic Function, and Behavior" is the cornerstone meeting for the worm neuroscience community. To enrich the C. elegans neuroscience research community the meeting will support and promote gender diversity, underrepresented groups and trainees and faculty from low- to middle-income countries. Lastly, to foster interactions between the C. elegans neuroscience and aging and metabolism community we will organize a joint session with the C. elegans Metabolism, Aging, Pathogenesis, and Stress on the first day of the CeNeuro2024 meeting focused on the neurobiology of aging, metabolism and neurodegeneration.

PI_NAMEs: BUELOW, HANNES ERICH (contact)

PROGRAM_OFFICER_NAME: CHURN, SEVERN BORDEN

PROJECT_TERMS: Achievement;Address;Aging;Back;Behavior;Biology;Caenorhabditis elegans;Collaborations;Communities;cost;Country;Development;Discipline;Disease;diversity and inclusion;Ethnic Origin;Event;Evolution;Faculty;Financial Support;Fostering;Funding;Gender;gender diversity;Goals;graduate student;Grant;Growth;Housing;Income;Individual;innovation;insight;International;Joints;Knowledge;low and middle-income countries;meetings;member;Mentors;Mentorship;Metabolism;Molecular;National Institute of Neurological Disorders and Stroke;Nerve Degeneration;Nervous System;neural;Neurobiology;neuron development;Neurosciences;Neurosciences Research;neurotransmission;novel;Oral;Participant;Pathogenesis;Physiology;Postdoctoral Fellow;posters;Research;Research Personnel;Science;Scientist;Sensory;Shapes;Stress;Students;success;symposium;synaptic function;synergism;Travel;Underrepresented Populations;Universities;verbal;Whole Organism;Wisconsin;Woman;Women's Group

PROJECT_TITLE: CeNeuro 2024: C.elegans Topic meeting Neuronal development, aging, synaptic function and behavior


NIH_SPENDING_CATS: Kidney Disease;Pediatric

ORG_CITY: CORAL GABLES

ORG_NAME: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE

PHR: Project Narrative The Miami Pediatric Nephrology Seminar is entering its 50th anniversary year as a sustaining landmark conference for the sub-specialty of Pediatric Nephrology as well as its many affiliates to be held March 15-17, 2024, in Miami Beach, Florida. The seminar is seen as a unique opportunity for pediatric and adult nephrologists, renal pathologists, neonatologists, pediatric urologists, transplant surgeons, nurses, nutritionists, and allied health professionals from all over the United States and the world. This is accomplished by the inclusion of diverse outstanding faculty, permitting extensive discussions and exchange of ideas and serves to stimulate young trainees in areas of research development, to foster interest in pediatric nephrology as a career choice and develop international collaborations.

PI_NAMEs: ABITBOL, CAROLYN LARKINS (contact)

PROGRAM_OFFICER_NAME: CONAGE-POUGH, JASON EDWARD

PROJECT_TERMS: Adult;Anniversary;Area;Blood Component Removal;career;Career Choice;career development;Childhood;Collaborations;Communities;Congresses;design;Development;Diagnosis;early-career faculty;Education;Environment;equity, diversity, and inclusion;Faculty;Fellowship;Financial Support;Florida;Fostering;Funding;Future;Genetic;Glomerulonephritis;Goals;Health;Hypertension;Incentives;interest;International;Justice;Kidney;Kidney Diseases;life span;medical specialties;Methods;Neonatal;Nephrology;Nurses;Nutritionist;Oral;Participant;Pathologist;Persons;Physicians;posters;profession allied to medicine;programs;Publishing;recruit;Renal Replacement Therapy;Research;research and development;Research Personnel;Schedule;Scientist;social;Suggestion;symposium;therapeutic development;Training;Transplant Surgeon;Transplantation;Travel;United States;United States National Institutes of Health;Urologist;virtual;Vision;Work

PROJECT_TITLE: 50th Anniversary Year: Miami Pediatric Nephrology SeminarSustaining the Specialty: Honoring the Past & Promoting the Future


NIH_SPENDING_CATS: Bioengineering;Lung;Machine Learning and Artificial Intelligence;Networking and Information Technology R&D (NITRD);Opioids;Patient Safety;Prevention

ORG_CITY: Columbus

ORG_DEPT: ANESTHESIOLOGY

ORG_NAME: OHIO STATE UNIVERSITY

ORG_STATE: OH

PHR: PROJECT NARRATIVE The objective of this conference is to improve definitions and innovations for identification and prevention of postoperative opioid-induced respiratory depression (OIRD) by developing working definition(s) of postoperative OIRD, outlining frameworks for the design of future clinical trials, and identifying opportunities for technology development to improve wireless monitoring and detection of postoperative OIRD and use AI to detect patterns that predict patient deterioration events in real-time. The conference will include a unique combination of industry partners and thought leaders from device technology and other stakeholders from healthcare information technology who will come together with clinician scientists and experts from data regulation to understand the challenges and opportunities from big data that comes out of wireless continuous ward monitoring. Participants will seek to build a consortium to advance science and improve patient safety in the context of a multi-pronged approach to OIRD prevention.

PI_NAMEs: KHANNA, ASHISH K;URMAN, RICHARD D. (contact)

PROGRAM_OFFICER_NAME: LAPOSKY, AARON D

PROJECT_TERMS: Acute;acute care;Advocacy;Area;Artificial Intelligence;authority;Big Data;Clinical;Clinical Trials;clinically significant;cloud based;Collaborations;Computer software;Computerized Medical Record;Consensus;Data;Dedications;depression prevention;design;Detection;Deterioration;Development;Device or Instrument Development;Devices;Diagnosis;digital;Discipline of Nursing;Event;Exclusion;experience;Expert Opinion;Fatigue;Fingerprint;Floor;Future;General Hospitals;Goals;Guidelines;Hawthorne Effect;Healthcare;Hospitals;Hour;Hypoventilation;Hypoxemia;improved;Incidence;Industry;industry partner;Industry Standard;Information Technology;innovation;Intervention;Intervention Studies;Knowledge;Life;Literature;Machine Learning;Measurement;Measures;meetings;Monitor;nursing intervention;Nursing Staff;Observational Study;Opioid;Outcome;Participant;Patient Monitoring;patient safety;Patients;Pattern;Perception;Physiological;portable monitoring;Postoperative Period;Prevention;Process;Professional Organizations;prospective;Publications;Reaction Time;Regulation;Research;Research Design;respiratory;risk prediction model;Role;safety outcomes;Science;Scientist;Secure;social media;Spottings;Stream;symposium;System;Technology;technology development;Time;transmission process;Ventilatory Depression;ward;wearable device;web site;wireless;wireless sensor;Wireless Technology;Work

PROJECT_TITLE: Improving definitions and innovations for identification and prevention of postoperative opioid induced respiratory depression (OIRD)


ORG_CITY: ANN ARBOR

ORG_DEPT: ANATOMY/CELL BIOLOGY

ORG_NAME: UNIVERSITY OF MICHIGAN AT ANN ARBOR

ORG_STATE: MI

PHR: Project Narrative Many neurological disorders involve abnormalities in cell physiology that unfold and progress over prolonged durations, ranging from days to years. Understanding these cellular processes in healthy and diseased states, as well as under pharmaceutical interventions, requires long-term readout of cell physiology in the living brain. The proposed work aims to develop novel technologies to enable such a long-term readout across living brains and to make these tools widely accessible to both basic and translational research communities.

PI_NAMEs: LINGHU, CHANGYANG  (contact)

PROGRAM_OFFICER_NAME: KIM, EUNYOUNG

PROJECT_TERMS: Aging;Autopsy;Basic Science;Biology;Brain;Cell Physiology;Cells;Chemicals;Circadian Rhythms;Communities;Development;Disease;Disease Progression;Engineering;Event;Fluorescent Probes;Gene Expression;Growth;Hour;Image;Imaging Techniques;Immune response;implantation;In Situ;in vivo;in vivo optical imaging;Information Storage;Intervention;Learning;Light;Magnetic Resonance Imaging;Measurement;Medicine;Memory;Methods;Microscopy;Modality;mouse model;Mus;Nervous System Disorder;Neurosciences;neurotechnology;new technology;novel;Optics;Performance;Pharmacologic Substance;Photobleaching;Physiological;promoter;Protein Engineering;Proteins;Recording of previous events;Resolution;Safety;self assembly;Signal Transduction;Sleep;Speed;System;Tape Recording;Technology;Time;Tissue imaging;tissue processing;Tissues;tool;transcription factor;Translational Research;Trees;ultrasound;Wood material;Work

PROJECT_TITLE: Temporally scalable recording of brain-wide single-cell physiology

STUDY_SECTION_NAME: Special Emphasis Panel[ZRG1 RCCS-L (70)]


ED_INST_TYPE: SCHOOLS OF LAW OR CRIMINOLOGY

NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Brain Disorders;Dementia;Neurodegenerative;Social Determinants of Health

ORG_CITY: ATLANTA

ORG_NAME: GEORGIA STATE UNIVERSITY

ORG_STATE: GA

PHR: Project Narrative The proposed Workshop, Career Development for Legally Trained Interdisciplinary Researchers in Aging and Health Sciences, aims to address the dearth of training available for legally trained researchers. The proposed Workshop will provide skills and career development guidance to help researchers harness legal training and knowledge to advance health sciences, including aging research and healthcare.

PI_NAMEs: ARIAS, JALAYNE J (contact)

PROGRAM_OFFICER_NAME: TORRES, DELANY

PROJECT_TERMS: Address;Affect;Affordable Care Act;Aging;Alzheimer's Disease;Alzheimer's disease risk;Appointment;Biological Markers;Biomedical Research;career;Career Choice;career development;Career Mobility;Collaborations;common rule;Communities;Criminal Justice;Dementia;Deposition;Development;Doctor of Philosophy;Education;Educational Curriculum;Educational process of instructing;Educational workshop;Empirical Research;Faculty;Feedback;Grant;Health;Health Sciences;Health Services Accessibility;Healthcare;Individual;innovation;Interdisciplinary Study;Interview;Knowledge;Laws;Lead;Legal;Long-Term Care;Marketing;Massachusetts;medical schools;member;Mentorship;Methods;older adult;Pattern;Pennsylvania;Persons;Policies;programs;Public Health;Publishing;Qualitative Research;Research;Research Personnel;Research Training;Scholarship;Schools;skill acquisition;skills;Statutes and Laws;Structure;symposium;System;Therapeutic;Thinking;Time;Training;Training Programs;Translating;United States Centers for Medicare and Medicaid Services;Universities;Vocational Guidance

STUDY_SECTION: AGCD

STUDY_SECTION_NAME: Career Development for Established Investigators and Conference Grants Study Section[AGCD-4]


ADMINISTERING_IC: HS

IC_NAME: AGENCY FOR HEALTHCARE RESEARCH AND QUALITY

ORG_CITY: WASHINGTON

ORG_NAME: ACADEMYHEALTH

PHR: AcademyHealth Annual Research Meeting Narrative AcademyHealth’s Annual Research Meeting (ARM) is the premier event for more than 3,000 health services researchers to disseminate their research and to enhance their careers by learning about new methods and networking with fellow researchers and users of their research. With 575 research presentations in sessions and 1,600 poster presentations, the ARM strives to synthesize, summarize, and communicate health services research findings to a broad range of individuals and organizations that have the capacity to use the information to improve health policy and clinical practice. The ARM’s objectives successfully complement and support AHRQ’s mission to improve the quality, safety, efficiency, and effectiveness of health care for all Americans.

PI_NAMEs: HAMMER, AMY  (contact)

PROGRAM_OFFICER_NAME: ZHANG, XINZHI

PROJECT_TITLE: Annual Health Services Research Meeting

STUDY_SECTION: HSVR

STUDY_SECTION_NAME: Healthcare Systems and Values Research[HSVR]


ADMINISTERING_IC: AR

IC_NAME: NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES

ORG_CITY: CHICAGO

ORG_NAME: RUSH UNIVERSITY MEDICAL CENTER

ORG_STATE: IL

PHR: Project Narrative This proposal is a request to support the 16th International Society of Bone Morphometry meeting (ISBM2024), which will take place on September 30 – October 3, 2023 at the Chestnut Conference Centre at University of Toronto (Toronto, Canada), immediately following the American Society for Bone and Mineral Research (ASBMR) Annual Meeting (September 27 – 30, 2023, Toronto, Canada). The meeting mission is to facilitate communication and collaboration among scientists from around the world interested in different aspects of bone morphometry.

PI_NAMEs: BOERCKEL, JOEL D;KO, FRANK  (contact)

PROGRAM_OFFICER_NAME: NICKS, KRISTY

PROJECT_TITLE: International Society of Bone Morphometry (ISBM) 2024 Meeting

STUDY_SECTION: AMS

STUDY_SECTION_NAME: Arthritis and Musculoskeletal and Skin Diseases Special Grants Study Section[AMS]


ADMINISTERING_IC: MD

IC_NAME: NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH DISPARITIES

NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Clinical Research;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Health Services;Prevention;Racial and Ethnic Minority Health Research;Social Determinants of Health

ORG_CITY: BERKELEY

ORG_DEPT: SOCIAL SCIENCES

ORG_NAME: UNIVERSITY OF CALIFORNIA BERKELEY

PHR: PA-21-151 UCB PI: Seth M. Holmes PROJECT NARRATIVE The “Social Medicine Cases for Health Equity” conference is focused on reducing health disparities through rigorous interdisciplinary dialogue between the social sciences and medicine. It will consist of experts in clinical medicine and experts in the social sciences integrating the methods and theories of their disciplines in the analysis of case studies of real patients from minority - including immigrant - communities. Findings from this conference will be disseminated in the “Case Studies in Social Medicine,” which has already been accepted for publication in The Lancet.

PI_NAMEs: HOLMES, SETH  (contact)

PROGRAM_OFFICER_NAME: JONES, NANCY LYNNE

PROJECT_TERMS: Affect;Agreement;Awareness;Caring;Case Series;Case Study;Clinical;Clinical Medicine;clinical practice;clinically actionable;Collaborations;Communicable Diseases;Complex;design;Discipline;Economics;Educational process of instructing;Educational workshop;effective intervention;Fostering;General Population;Goals;Health;health care availability;health determinants;health disparity;health equity;Health Policy;health practice;Health Services;Health system;Healthcare;Immigrant;Immigrant community;improve minority health;improved;Individual;individual patient;Inequity;infant morbidity/mortality;Infant Mortality;innovation;interdisciplinary collaboration;Interdisciplinary Study;Intervention;Journals;Knowledge;knowledge translation;lectures;Light;Maternal Mortality;Medical;Medical Students;Medicine;Methodology;Methods;Minority;Minority Groups;minority health;minority health disparity;Minority Health Research;minority patient;National Institute on Minority Health and Health Disparities;New England;novel;Outcome;patient-clinician communication;Patients;podcast;Policies;Policy Maker;poor health outcome;Population;Primary Care;programs;public health research;Publications;Publishing;Recommendation;Reduce health disparities;Research;rural dwellers;Scientist;Series;Sexual and Gender Minorities;Shapes;social;social factors;Social Medicine;Social Policies;Social Processes;Social Sciences;social structure;socioeconomics;Structural Racism;symposium;theories;Translating;Translations;United States;Work

PROJECT_TITLE: SOCIAL MEDICINE CASES FOR HEALTH EQUITY

STUDY_SECTION_NAME: Special Emphasis Panel[ZMD1 XLN (J1)]


ADMINISTERING_IC: TR

IC_NAME: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

NIH_SPENDING_CATS: Nutrition

ORG_CITY: PHILADELPHIA

ORG_NAME: UNIVERSITY OF PENNSYLVANIA

ORG_STATE: PA

PHR: PROJECT NARRATIVE This application requests partial support for the 13th International Copper Meeting: From Mechanisms to Therapy, which is focused on focused on genetic, molecular, and biochemical mechanisms underlying copper biology and chemistry in normal physiology and disease and proof-of-concept or clinically tractable means to translate these discoveries. Both basic/translational scientists and clinicians at this conference will be exposed to the emerging concepts in the copper field, including but not limited to advanced tools to study copper biology, structural biology of cuproproteins, copper at the host pathogen interface, intracellular and organismal copper trafficking and storage, and inherited diseases and somatic diseases associated with alterations in copper homeostasis. Together, participants will be encouraged to explore deeper mechanistic understanding of the links between copper homeostasis and human diseases with translational relevance.

PI_NAMEs: BRADY, DONITA C (contact)

PROGRAM_OFFICER_NAME: BROOKS, PJ

PROJECT_TERMS: Academia;Achievement;Active Sites;Affinity;Amino Acids;Award;Basic Science;bench to bedside;Binding;Biochemical;Biological Process;Biology;Biomedical Research;cancer initiation;Carbohydrates;career;Cell Physiology;Chemicals;Chemistry;Clinic;Clinical;Clinical Medicine;Clinical Sciences;cofactor;Collaborations;combat;Copper;deprivation;dietary;Dietary intake;Discipline;Disease;Distal;Educational workshop;Ensure;Environment;Enzymes;experience;Exposure to;Failure;Financial Support;Future;Genetic;Genetic Diseases;Genetic study;Goals;Hereditary Disease;Homeostasis;Human;human disease;Immunity;Industry;Infection;innovation;International;Investments;Knowledge;Link;Lipids;Malignant Neoplasms;meetings;Metabolic syndrome;metabolic-associated fatty liver disease;Metabolism;Metals;Methodology;Micronutrients;Mitochondria;Molecular;Monitor;Motor;Nervous System Disorder;Neuropathy;non-alcoholic fatty liver disease;novel strategies;novel therapeutics;Nucleotides;Nutrient;Organism;Outcome;Oxidation-Reduction;Participant;pathogen;Physiological;Physiology;posters;Productivity;Proteins;Request for Applications;Research;Research Personnel;response;Scientist;Senior Scientist;Series;structural biology;success;symposium;Syndrome;Systems Biology;Technology;Therapeutic;therapeutic development;therapeutic target;tool;Toxic effect;trafficking;Training;Transition Elements;Translating;translational physician;Translational Research;translational scientist;Travel;tumor progression;Vertebral column

STUDY_SECTION_NAME: Special Emphasis Panel[ZTR1 CG-2 (02)]


NIH_SPENDING_CATS: Aging;Biotechnology;Neurosciences

ORG_CITY: SAN FRANCISCO

ORG_NAME: J. DAVID GLADSTONE INSTITUTES

PHR: NARRATIVE This application seeks funding to support Trainee-focused workshop and travel support for pre- and post-doctoral scholars to attend the upcoming 31st annual meeting of the American Society for Neural Therapy and Repair. This meeting will promote introductions and ongoing interaction between young and senior scientists in academia and industry, as well as clinical professionals, to jointly discover and develop new treatments for neurological disorders. This interactive approach between basic scientists and clinicians cultivates a safe and inclusive culture of translational learning, research and career development across all stages and communities.

PI_NAMEs: ZHOLUDEVA, LYANDYSHA VIKTOROVNA (contact)

PROGRAM_OFFICER_NAME: LAVAUTE, TIMOTHY M

PROJECT_TERMS: Academia;age related neurodegeneration;Alzheimer's Disease;American;Area;Award;Basic Science;career;career development;Cell Therapy;Cell Transplantation;Clinical;Clinical Trials;Collaborations;Communities;cost;Creativeness;curative treatments;Data;Dedications;Development;Disease;Educational workshop;Emotional;Ensure;Environment;equity, diversity, and inclusion;Event;experience;Family;Florida;Fostering;functional loss;Funding;gene therapy;Goals;graduate student;Huntington Disease;Individual;Industry;Injury;innovation;Institution;Intellectual Property;interest;Learning;Legal patent;Life;Medical Students;meetings;member;Mentors;nerve injury;Nervous System;Nervous System Disorder;neural;Neurologic;Neurons;novel;novel strategies;Online Systems;Oral;Outcome Measure;Parkinson Disease;Pathway interactions;Patients;Persons;Play;Postdoctoral Fellow;posters;pre-clinical;pre-doctoral;programs;Relaxation;repaired;Reproducibility;Research;research and development;Research Personnel;Role;Scientific Societies;Scientist;Senior Scientist;Site;Societies;spinal cord and brain injury;Stroke;Students;success;symposium;Technology;Training;Training and Education;translational approach;Translational Research;Translations;Travel;undergraduate student;United States;Universities;Writing

PROJECT_TITLE: American Society for Neural Therapy and Repair Annual Conference


NIH_SPENDING_CATS: Childhood Obesity;Clinical Research;Clinical Trials and Supportive Activities;Maternal Health;Nutrition;Obesity;Pediatric;Pregnancy;Prevention;Women's Health Research

ORG_CITY: BATON ROUGE

ORG_NAME: LSU PENNINGTON BIOMEDICAL RESEARCH CTR

ORG_STATE: LA

PHR: This is an administrative supplement to support the food provision with BistroMD for the weight maintenance intervention in the Healthy Mama's trial.

PI_NAMEs: PHELAN, SUZANNE ;REDMAN, LEANNE MAREE (contact)

PROGRAM_OFFICER_NAME: EVANS, MARY

PROJECT_TERMS: 37 weeks gestation;Administrative Supplement;Black race;Body Composition;Caloric Restriction;cardiometabolic risk;Child;clinically significant;Data;effective therapy;energy balance;excessive weight gain;Fatty acid glycerol esters;fetal;Food;gestational weight gain;Goals;Growth;Guidelines;Health;Healthcare;Hispanic;improved;innovation;Intervention;intervention effect;lifestyle intervention;maternal obesity;maternal weight;Measures;Morbid Obesity;Morbidity - disease rate;Neonatal;novel;Obesity;Outcome;Postpartum Period;Pregnancy;Pregnancy Trimesters;pregnant;Pregnant Women;Prospective, cohort study;Randomized;randomized trial;Randomized, Controlled Trials;Recommendation;Risk Factors;Safety;Second Pregnancy Trimester;Testing;Third Pregnancy Trimester;treatment as usual;Weight Gain;weight maintenance;Weight maintenance regimen;Woman;women's treatment;Women's trial

PROJECT_TITLE: Promoting fat loss during pregnancy in women with grade 2 and 3 obesity


NIH_SPENDING_CATS: Biodefense and Related Countermeasures;Climate-Related Exposures and Conditions;Emerging Infectious Diseases;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Infectious Diseases;Vector-Borne Diseases

ORG_CITY: GALVESTON

ORG_NAME: UNIVERSITY OF TEXAS MED BR GALVESTON

PHR: This meeting will bring together clinicians, laboratorians, and field researchers to promote interest in tropical and emerging infectious diseases and expand the pipeline for developing a strong clinician-scientist and translational scientist workforce. The 2½-day scientific meeting is to be held on the University of Texas Medical Branch campus in Galveston, Texas. It will provide a forum for junior clinicians and scientists to gain a vision for how they could successfully embark on a career as a physician-scientist or translational scientist.

PI_NAMEs: MCLELLAN, SUSAN LESLIE FAVROT;MELBY, PETER C. (contact)

PROGRAM_OFFICER_NAME: STRICKLER-DINGLASAN, PATRICIA M

PROJECT_TERMS: Address;Advertising;Aedes;Antimicrobial Resistance;Arboviruses;Arthropod Vectors;arthropod-borne;Bacterial Infections;Belief;career;career development;Caring;Child;Child Care;climate change;Clinical;clinical care;Clinical Research;clinically relevant;combat;Communicable Diseases;Competence;Containment;COVID-19 pandemic;Disabled Persons;Disease Outbreaks;Doctor of Philosophy;Effectiveness;Electronics;emerging antimicrobial resistance;Emerging Communicable Diseases;Emerging infection;emerging pathogen;emerging tropical infectious disease;Ensure;Epidemic;Evaluation;experience;Filovirus;Funding;Future;Goals;Grant;Health;Human;Infection;Infectious Agent;Interdisciplinary Study;interest;Laboratories;Leadership;Learning;Medical;meetings;Mentors;Monkeypox;multidisciplinary;neglected tropical diseases;next generation;Oral;pandemic disease;Paper;Participant;pathogen;Pathogenesis;Patient Care;peer;personal protective equipment;Physicians;Politics;Postdoctoral Fellow;posters;programs;Public Health;Public Opinion;Publishing;Relationship-Building;Request for Proposals;Research;research facility;Research Personnel;response;Scholarship;Science;Scientist;Structure;symposium;System;Texas;Time;Translational Research;translational scientist;Travel;treatment center;Underrepresented Minority;United States National Institutes of Health;Universities;vector;vector-borne;Vector-transmitted infectious disease;Virus Diseases;Vision;Woman;Zoonoses

PROJECT_TITLE: Tropical and Emerging Infectious Diseases for the Clinician and Translational Investigator


ADMINISTERING_IC: EB

IC_NAME: NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING

ORG_DEPT: BIOMEDICAL ENGINEERING

ORG_NAME: EMORY UNIVERSITY

PHR: Project Narrative “fNIRS2024” is an international meeting of researchers, physicians, and engineers in academia and industry who are interested in applying diffuse optics methods to the study of normal brain function and its alteration in disease. This meeting will leverage the diverse attendee’s expertise to identify opportunities and address challenges for the field in order to develop new tools to enable the detection, characterization, quantification, and treatment monitoring of brain disease processes.

PI_NAMEs: BUCKLEY, ERIN MCGUIRE (contact)

PROGRAM_OFFICER_NAME: GUTEKUNST, DAVID JOSEPH

PROJECT_TERMS: Academia;Address;Advanced Development;Award;Basic Science;Biomedical Engineering;Biophotonics;Boston;Brain;Brain Diseases;Brazil;career;Cerebral cortex;Child;Clinical;clinical application;cognitive neuroscience;Collaborations;college;Communication;Communities;computer science;cost;Data Analyses;data modeling;Detection;Development;Diffuse;Disease;doctoral student;Education;Educational Status;Engineering;Environment;equity, diversity, and inclusion;Event;Exercise;experience;Fees;Fellowship;Fostering;functional near infrared spectroscopy;Funding;Future;Gender;Geography;Health;hemodynamics;Human;Hybrids;Imaging Device;imaging scientist;Imaging Techniques;improved;Industry;interest;International;lecturer;lectures;Light;London;Medical;Medical Imaging;meetings;Methods;mid-career faculty;Minority;Modality;Monitor;multidisciplinary;Nature;neuroimaging;Neurosciences;next generation;older patient;Optical Methods;Optics;Oral;photonics;Physicians;Physics;Population;Postdoctoral Fellow;posters;Process;professor;programs;Radiology Specialty;Research;Research Personnel;Resource-limited setting;Scalp structure;Scientist;social neuroscience;Societies;Special Population;Structure;Students;symposium;Technology;tool;Translational Research;Travel;Underrepresented Minority;Universities;virtual;Vision;Voice;Walking;Woman;Work

PROJECT_TITLE: fNIRS2024 Birmingham

STUDY_SECTION_NAME: Special Emphasis Panel[ZEB1 OSR-F (J1)]


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Cancer;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Racial and Ethnic Minority Health Research;Social Determinants of Health

ORG_NAME: AMERICAN ASSOCIATION FOR CANCER RESEARCH

PHR: PROJECT NARRATIVE Analysis of cancer incidence and mortality data underscores the disproportionate impact of cancer in specific racial, ethnic, and medically underserved groups. These disparities arise from a complex interplay of several elements including socioeconomic, cultural, systemic, biological, and genetic factors. This conference series serves as a platform for bringing together basic scientists, physicians, behavioral researchers, population scientists, healthcare experts, and members of the community to encourage interdisciplinary collaborations, foster the development of a diverse cancer workforce, and ultimately make substantial progress in eradicating disparities in cancer.

PI_NAMEs: FOTI, MARGARET  (contact)

PROGRAM_OFFICER_NAME: CALZOLA, JESSICA MARIE

PROJECT_TERMS: Address;Advocate;American Association of Cancer Research;Behavioral;Biological;cancer health disparity;Cancer Science;career;Caring;Clinical;cohort;Collaborations;Committee Members;Communities;Complex;Data;Development;Disparity;Education;Elements;ethnic minority;Ethnic Origin;experience;falls;Fostering;Future;Genetic;Goals;Government;Growth;Healthcare;Incidence;interdisciplinary collaboration;Knowledge;Location;Malignant Neoplasms;medically underserved;medically underserved population;member;Mentors;Methodology;Minority-Serving Institution;mortality;novel;Patients;Physicians;Policies;Population;Population Heterogeneity;posters;programs;Public Health;Race;racial disparity;racial minority;Research;Research Personnel;Scientist;Series;skills;socioeconomics;Students;symposium;Underserved Population;United States;Work

PROJECT_TITLE: AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved


ORG_CITY: Aurora

ORG_DEPT: MICROBIOLOGY/IMMUN/VIROLOGY

ORG_NAME: UNIVERSITY OF COLORADO DENVER

ORG_STATE: CO

PHR: PUBLIC HEALTH RELEVANCE The WRC is an outstanding and unique forum in which trainees learn career skills by presenting their research and interacting with more senior researchers. The meeting offers a balance between host-pathogen work and the basic microbial biology that underpins the study of disease. 1

PI_NAMEs: BRINSMADE, SHAUN R;SCHURR, MICHAEL JOHN (contact)

PROJECT_TITLE: 68th Wind RIver Conference on Procaryotic Biology

STUDY_SECTION_NAME: Special Emphasis Panel[ZAI1 LK-D (J1)]


NIH_SPENDING_CATS: Cardiovascular;Cerebrovascular;Congenital Structural Anomalies;Heart Disease;Hematology;Lung;Pediatric

ORG_CITY: STANFORD

ORG_NAME: STANFORD UNIVERSITY

ORG_STATE: CA

PHR: NARRATIVE The main objective of the North American Vascular Biology Organization (NAVBO) 2024 Vasculata Conference is to introduce cutting-edge research at Stanford University, UC San Francisco and UC Berkeley to the general vascular biology audience. A uniquely tailored translational science conference combined with training and professional growth opportunities makes the 2024 Vasculata Conference a favorable option for underrepresented groups in science. This initiative aligns well with the stated mission of NHLBI to promote the next generation of research scientists.

PI_NAMEs: SPIEKERKOETTER, EDDA FRAUKE (contact);TENG, JOYCE MING CAO

PROGRAM_OFFICER_NAME: CHARETTE, MARC F

PROJECT_TERMS: 3-Dimensional;Address;Affect;Age;American;Anemia;Area;Basic Science;bench to bedside;Biological Sciences;biological systems;Biology;Blood;Blood coagulation;Blood Coagulation Disorders;Blood Vessels;California;Cardiopulmonary;Cardiovascular Diseases;Cardiovascular system;career;career development;Cells;Cellular biology;cerebrovascular;Cerebrovascular Disorders;Chicago;Childhood;Chronic Disease;Clinic;Clinical;clinical application;college;Communities;Congenital Heart Defects;cost;COVID-19 pandemic;Data Analyses;Data Collection;Death Rate;Development;Disease;disease model;drug repurposing;drug testing;Education;Educational Curriculum;Educational workshop;Endothelial Cells;Environment;Exposure to;Faculty;falls;field study;Funding;Generations;Goals;Grant;Growth;Healthcare;Heart Diseases;Hematological Disease;Hematopoietic Neoplasms;Hereditary hemorrhagic telangiectasia;high throughput screening;Historically Black Colleges and Universities;Home;hospitalization rates;Illinois;Immune;improved;induced pluripotent stem cell;innovation;insight;Institution;interest;Knowledge;knowledge translation;lectures;Link;Literature;Lung Diseases;malformation;meetings;Mind;mindfulness;Minority Groups;Minority Recruitment;Mission;Multiomic Data;National Heart, Lung, and Blood Institute;next generation;novel;novel strategies;novel therapeutics;Organ;outreach;Pediatric Hospitals;posters;pre-clinical;programs;Public Health;Pulmonary Circulation;Pulmonary Hypertension;Reading;Recording of previous events;Research;Research Personnel;San Francisco;Scholarship;Science;Scientist;Silicon;Site;Stroke;Students;summer research;symposium;Techniques;Time;Tissue imaging;tool;Training;Translating;Translational Research;Underrepresented Minority;Underrepresented Populations;United States;Universities;vascular abnormality;Vascular Diseases;Woman;Writing

PROJECT_TITLE: Vasculata 2024


NIH_SPENDING_CATS: Kidney Disease;Urologic Diseases

ORG_CITY: SALT LAKE CITY

ORG_NAME: UNIVERSITY OF UTAH

ORG_STATE: UT

PHR: Narrative The purpose of this application is to request travel funds to support trainees who wish to attend and present their research at the American Physiological Society Summit Meeting (on April 4-7th, 2024 in Long Beach, CA) and be part of a unique educational forum for scientists who study renal and urothelial cell function in health and disease. By supporting the travel, education, and development of these promising early career scientists, we hope to expand and diversify the current epithelial biology workforce, ultimately increasing research in the scope of the KUH.

PI_NAMEs: WYNNE, BRANDI MICHELE (contact)

PROJECT_TERMS: American;Area;Atmosphere;Award;Biological Process;biological research;Biology;Biomedical Research;Budgets;career;career development;Caring;Cell Physiology;Cellular biology;Child;Coffee;Collaborations;Communication;cost;Data;Development;Disabled Persons;Discipline;Disease;Education;Educational workshop;Eligibility Determination;Ensure;Epithelial Cells;Epithelial Physiology;Epithelium;Event;Exhibits;experience;Exposure to;Family;family support;Feedback;Funding;gastrointestinal;Goals;Health;informal atmosphere;Infrastructure;instructor;Intention;interest;Interest Group;International;Journals;Kidney;kidney cell;knowledge base;lecturer;lectures;Lung;meetings;member;Mentors;Mission;Names;National Institute of Diabetes and Digestive and Kidney Diseases;Nature;Newsletter;Nonprofit Organizations;Oral;oral communication;Organizational Objectives;peer;Physiological;Physiology;Postdoctoral Fellow;posters;Publishing;Recording of previous events;Request for Applications;Research;Research Personnel;Resources;Science;Scientist;Seasons;Senior Scientist;Services;Societies;Special needs;Structure;Students;success;Surveys;symposium;Talents;Time;Training;Travel;urologic;Urothelial Cell;Urothelium;Work

PROJECT_TITLE: Funding for Renal/Urothelial Early Career Researchers at the American Physiology Society Summit ETG Sessions


FUNDING_MECHANISM: SBIR-STTR RPGS

NIH_SPENDING_CATS: Biotechnology;Diabetes;Kidney Disease

ORG_CITY: San Francisco

ORG_NAME: REVEL PHARMACEUTICALS INC.

PHR: PROJECT NARRATIVE Diabetic kidney disease, the leading cause of kidney failure, results from high blood glucose damaging the blood vessels in the kidneys. This damage includes glycation of extracellular proteins, which results in accumulation of advanced glycation end products (AGEs), triggering vascular dysfunction, fibrosis, and loss of kidney function. Revel Pharmaceuticals is developing a novel class of therapeutics designed to enzymatically eliminate AGEs thus removing a significant driver of DKD.

PI_NAMEs: CRAVENS, AARON  (contact)

PROJECT_TERMS: Address;Advanced Development;Advanced Glycosylation End Products;Affect;Amino Acids;Amino Sugars;Automobile Driving;Binding;blood damage;Blood Glucose;Blood Vessels;Cadaver;Cessation of life;Chronic;Clinical;Complication;Complications of Diabetes Mellitus;Data;design;Development;Diabetes Mellitus;diabetic;Diabetic Nephropathy;Directed Molecular Evolution;Disease;drug candidate;End stage renal failure;Engineering;enzyme activity;Enzymes;Excision;Exposure to;Extracellular Protein;FDA approved;Fibrosis;Functional disorder;global health;glycation;glycemic control;Goals;Grant;Heart Diseases;Heart failure;human tissue;Hydrophobicity;Hyperglycemia;improved;in vivo;Inflammatory;innovation;Insulin-Dependent Diabetes Mellitus;Kidney;Kidney Failure;Kinetics;lead optimization;Ligation;Lysine;Maillard Reaction;metabolic phenotype;Modeling;Modification;Mus;N(6)-carboxymethyllysine;Non-Insulin-Dependent Diabetes Mellitus;novel;novel therapeutics;Oxidases;Pathogenesis;Pathogenicity;Patients;Peptides;Persons;Pharmacologic Substance;Phase;Physiological;Post-Translational Protein Processing;programs;protein aggregation;Proteins;Proteomics;rational design;Reaction;receptor;receptor for advanced glycation endproducts;Renal function;repaired;Research;Sampling;Signal Transduction;Small Business Innovation Research Grant;Specificity;Stroke;Structure;Substrate Specificity;Surface;targeted treatment;Testing;Therapeutic;therapeutic development;therapeutic enzyme;Tissue Sample;Tissues;type I and type II diabetes;Variant;Vascular Diseases;Vascular Permeabilities;Work

PROJECT_TITLE: Development of advanced glycation end product (AGE)-breaking enzymes as a novel therapy for the treatment of diabetic kidney disease

STUDY_SECTION_NAME: Special Emphasis Panel[ZRG1 KUDS-R (11)]


ADMINISTERING_IC: DD

IC_NAME: NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES

ORG_CITY: IOWA CITY

ORG_NAME: UNIVERSITY OF IOWA

ORG_STATE: IA

PHR: PROJECT NARRATIVE The Iowa Center for Birth Defects Research and Prevention, in collaboration with premier scientists locally, nationally, and internationally, will expand our leadership role in investigating environmental exposures and gene variants for major birth defects. Our research will provide important insights into understanding the combined roles of exposures and variants in preventing or reducing adverse consequences of major birth defects. Findings will be shared with scientists, healthcare providers, policymakers, and families with the goal to develop appropriate prevention interventions and resources for families affected by major birth defects.

PI_NAMEs: CONWAY, KRISTIN ;ROMITTI, PAUL A (contact)

PROGRAM_OFFICER_NAME: OGUNFUYI, SHAKIRATU BIOLA

PROJECT_TITLE: Iowa CBDRP Comp A: BD-STEPS Core


FUNDING_MECHANISM: OTHERS

ORG_CITY: TUCSON

ORG_NAME: UNIVERSITY OF ARIZONA

ORG_STATE: AZ

PHR: PROJECT NARRATIVE The objective of this proposal is to improve mining safety and health training in the western United States and support efforts to reduce mining injuries, illnesses and fatalities. Despite continued improvements over time, mining injuries and fatalities continue to occur in the mining industry, and reducing occupational illnesses remains challenging. Building on our past mine training grants, we will expand and enhance the Learning Laboratories program to be more responsive to the specific health and safety challenges that each operator faces and greatly improve collaboration through three-way partnerships with industry, academia, and government agencies.

PI_NAMEs: BROWN, LEONARD D (contact)

PROJECT_TITLE: Western Mining Safety & Health Training Resource Center: Facilitating Research to Practice through Learning Laboratories


ED_INST_TYPE: EARTH SCIENCES/RESOURCES

ORG_CITY: GOLDEN

ORG_DEPT: ENGINEERING (ALL TYPES)

ORG_NAME: COLORADO SCHOOL OF MINES

PHR: Project Narrative The Colorado School of Mines (CSM) Energy, Mining and Construction Industry Safety (EMCIS) program will provide a comprehensive approach intended to meet the safety and health training needs of the Western mining industry by providing a high quality, interactive training experience that targets mine workers and underserved audiences throughout the Western states, including safety and health professionals, mine management and supervision, contractors, consultants, suppliers, equipment manufacturers, and academia (faculty, staff and students). Through the training and educational activities offered by CSM, trainees will be exposed to critical concepts using best industry practices and adult learning techniques to facilitate the development and retention of fundamental skillsets essential to advancing safe and healthy work practices and the ability to identify and eliminate hazards. Future benefits of these efforts are to provide mine workers with the core values and knowledge necessary for positive, life-long improvements to the mining industry, as well as proactive practices and tools vital for reducing the risk associated with injuries and illnesses.

PI_NAMEs: MILLER, HUGH  (contact);REIHER, MICHELLE

PROJECT_TITLE: Enhanced Safety and Health Training for Western Mine Workers


ORG_CITY: HOUSTON

ORG_DEPT: PUBLIC HEALTH & PREV MEDICINE

ORG_NAME: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

PHR: Project Narrative While birth defects are the number one cause of mortality, disability, and medical expenditures within the first year of life, their etiology is unknown in most affected individuals, and most research in the U.S. has focused on populations with relatively limited diversity (e.g., primarily non-Hispanic white subjects). To address this gap, the Texas Center for Birth Defects Research and Prevention proposes to contribute our diverse population to BD-STEPs, as well as our team’s experience and resources as one of the largest birth defects registries in the world, and as national leaders in birth defects surveillance, research, and training of the next generation of birth defects epidemiologists. By growing our ongoing collaborations with our partners at the CDC and NBDPS/BD-STEPS Centers, we expect to identify modifiable genetic and non-genetic risk factors for birth defects with important implications for future prevention strategies designed to reduce risk for birth defects and improve health among affected individuals.

PI_NAMEs: AGOPIAN, A.J.  (contact);LUPO, PHILIP ;SHUMATE, CHARLES J

PROJECT_TITLE: Comp A: Texas BD-STEPS III Core


PHR: NARRATIVE Birth defects are the leading cause of infant mortality in the US. Birth defects also have enormous associated emotional and fiscal costs. With this new funding opportunity (BD-STEPS III), the California Center, both independently and in collaboration with other Centers, will conduct studies that will identify potential modifiable risk factors for selected birth defects to reduce the public health burden of birth defects in the US.

PI_NAMEs: SHAW, GARY M (contact)

PROJECT_TITLE: Comp A:  CALIFORNIA CENTER OF BD-STEPS III FINDING CAUSES AND PREVENTIVES OF BIRTH DEFECTS


ADMINISTERING_IC: IP

IC_NAME: NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES

ORG_CITY: AUSTIN

ORG_NAME: UNIVERSITY OF TEXAS AT AUSTIN

PHR: PROJECT NARRATIVE We will build innovative models for evaluating multifaceted influenza interventions across the US and engage with the CDC Modeling Network to establish a culture of collaboration and diverse evidence base for influenza prevention and control. By elucidating immune-mediated competition between viruses and the population-level impacts of new antiviral regimens, our models will enable the optimization of targeted vaccine, antiviral and non-pharmaceutical interventions strategies. We will leverage our new visualization platform and longstanding collaborations with public health officials to translate modeling results into actionable insights for mitigating seasonal and pandemic influenza and for addressing socioeconomic and geographic disparities in influenza burden.

PI_NAMEs: MEYERS, LAUREN ANCEL (contact)

PROJECT_TITLE: RFA-IP-22-004, Modeling toolkit to evaluate multifaceted control strategies for seasonal and pandemic influenza


ORG_CITY: MENANDS

ORG_NAME: NYSDOH/HEALTH RESEARCH, INC.

ORG_STATE: NY

PHR: Project Narrative Birth defects are a leading cause of infant mortality and childhood disability, with the majority of birth defects having an unknown origin. Given that half of pregnant people report medication use, the prevalence of chronic conditions (such as obesity, diabetes, and hypertension) is increasing during pregnancy, the global spread of infectious diseases (such as COVID-19 and Zika virus), and the racial/ethnic and social disparities in the burden of birth defects, it is imperative to prioritize research on how these factors affect birth defect risk. The New York State Center for Birth Defects Research and Prevention will do so by building on our experience with NBDPS and BD-STEPS, using innovative exposure assessment and analytic methods to better understand birth defect causes and inform prevention strategies that will reduce the public health burden of birth defects.

PI_NAMEs: HOWLEY, MEREDITH M (contact)

PROJECT_TITLE: New York State BD-STEPS: Component A and B


ORG_CITY: BOSTON

ORG_NAME: NORTHEASTERN UNIVERSITY

ORG_STATE: MA

PHR: The objective of this proposal is to advance the science of modeling and contribute novel methods and data analytics tools that will increase the understanding of seasonal and pandemic influenza in the context of the network of modeling teams coordinated by the CDC. To address these challenges, we plan to develop a novel global modeling framework, contribute new data and methods for improve the accuracy and validation of flu modeling approaches, and evolve successful methodologies to advance the analysis of layered intervention with artificial Intelligence.

PI_NAMEs: VESPIGNANI, ALESSANDRO  (contact)

PROJECT_TITLE: RFA-IP-20-003, FluMod - Center for the Multiscale Modeling of Pandemic and seasonal Flu Prevention and Control


ORG_CITY: PITTSBURGH

ORG_NAME: UNIVERSITY OF PITTSBURGH AT PITTSBURGH

PHR: Project Narrative This research will produce models of influenza that can be used by the public and policy makers to prepare for and prevent influenza outbreaks. By making the prediction of influenza as accurate and valuable as weather forecasting, we should be able to predict the impact of individual behaviors and public health interventions to prevent and treat seasonal influenza and reduce the potential harm of pandemic flu.

PI_NAMEs: ROBERTS, MARK STENIUS (contact)

PROJECT_TITLE: RFA-IP20-003: Individual-based Simulation of Seasonal and Pandemic Influenza Epidemics - supplement Emergency Response to the COVID-19 Pandemic


ORG_CITY: CHAPEL HILL

ORG_NAME: UNIV OF NORTH CAROLINA CHAPEL HILL

ORG_STATE: NC

PHR: Project Narrative Component A: BD-STEPS Core at the NC Center for Birth Defects Research and Prevention Birth defects affect approximately three percent of all births yet account for 20 percent of infant deaths and contribute substantially to childhood morbidity and long-term disability. The North Carolina Center for Birth Defects Research and Prevention (NCCBDRP) is a long-standing partnership between the Department of Epidemiology at the University of North Carolina at Chapel Hill, and the North Carolina Birth Defects Monitoring Program at the North Carolina Division of Public Health. The NCCBDRP will implement the multi-site, population-based Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) in a demographically diverse 33-county area of North Carolina to identify novel epidemiologic and genetic risk factors for major structural birth defects and to advance public health strategies for birth defects prevention.

PI_NAMEs: DESROSIERS, TANIA A.;OLSHAN, ANDREW  (contact)