NIH_SPENDING_CATS: Brain Disorders;Chronic Pain;Clinical Research;Clinical Trials and Supportive Activities;Contraception/Reproduction;Endometriosis;Estrogen;Headaches;Migraine;Neurosciences;Pain Research;Women's Health Research

PI_NAMEs: STRATTON, PAMELA  (contact)

PROJECT_TERMS: Affect;Anatomy;angiogenesis;Anxiety;Biopsy;Blood;Central Nervous System;chronic depression;chronic pain;chronic painful condition;chronic pelvic pain;Chronic stress;Classification;Clinical Trials;Cohort Studies;comorbidity;Corticotropin;Corticotropin-Releasing Hormone;Data;disability;Disease;endometriosis;Endometrium;Enrollment;Estrogens;Evaluation;experience;Functional disorder;Future;Genetic;Goals;Growth Factor;Headache;Health;healthy volunteer;Hydrocortisone;hypothalamic-pituitary-adrenal axis;Immune;Investigation;Lesion;Location;Measures;Mental Depression;Methods;Michigan;Migraine;Nerve;neural;Neurosecretory Systems;Operative Surgical Procedures;Pain;Pain Threshold;Patients;Pelvic Pain;placebo controlled trial;Placebos;Predictive Factor;prospective;Quality of life;Race;racial diversity;Raloxifene;Randomized;Recording of previous events;response;Selective Estrogen Receptor Modulators;Severities;Specimen;Stratification;Symptoms;Syndrome;Testing;Tissues;Update;Urine;Woman;Women's cohort;Women's study;women's treatment

PROJECT_TITLE: Neural Immune and Genetic Influences on Chronic Pelvic Pain and Endometriosis


ACTIVITY: ZIA

ADMINISTERING_IC: NS

ARRA_FUNDED: N

FUNDING_MECHANISM: INTRAMURAL RESEARCH

IC_NAME: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

NIH_SPENDING_CATS: Chronic Pain;Clinical Research;Clinical Trials and Supportive Activities;Contraception/Reproduction;Endometriosis;Natural Products;Neurosciences;Pain Research;Women's Health Research

PROJECT_TERMS: allostatic load;Analgesics;analog;Anxiety;botulinum neurotoxin injection;Botulinum Toxins;Caring;Case Study;central sensitization;chronic pain;chronic pelvic pain;clinical care;Clinical Trials;cohort;Complex;Data;Data Analyses;disability;Disease;Dystonia;effective therapy;Effectiveness;effectiveness evaluation;Elements;Eligibility Determination;endometriosis;Equipment and supply inventories;Esophageal achalasia;Etiology;experience;Fatigue;Functional disorder;Headache;Health Surveys;healthy volunteer;Hemifacial Spasm;Human;improved;Injections;Interstitial Cystitis;Irritable Bowel Syndrome;Measurement;Measures;Medical;Mental Depression;microbial;Muscle;Muscle Contraction;Myofascial Pain Syndromes;Nociception;Operative Surgical Procedures;Pain;Pathway interactions;patient response;Patients;Pelvic Floor Muscle;Pelvic floor structure;Pelvic Pain;Pelvis;Persistent pain;placebo controlled study;Placebos;primary outcome;Publishing;Quality of life;Questionnaires;Randomized;Recording of previous events;Rome;secondary outcome;Sleep;Sodium Chloride;Source;Spasm;spasticity;Standardization;Time;Toxin;treatment response;Visual;Water;Woman

PROJECT_TITLE: The effectiveness of Botulinum toxin on persistent pelvic pain in women with endometriosis


NIH_SPENDING_CATS: Neurosciences

ORG_NAME: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

PI_NAMEs: ROLL-MECAK, ANTONINA  (contact)

PROJECT_TERMS: Affect;axon regeneration;beta Tubulin;Biochemical;Brain;C-terminal;Cell division;cell type;Cells;Code;combinatorial;Complex;Coupled;Cryoelectron Microscopy;Development;Disease;early onset;enzyme mechanism;Enzymes;Family;Feedback;Fluorescence;Glutamates;Goals;Human;Human Engineering;inhibitor;Intracellular Transport;Kinetics;Lead;Length;Link;Malignant Neoplasms;Maps;Mass Spectrum Analysis;Methods;Microtubule Polymerization;Microtubule-Associated Proteins;Microtubules;Modification;Molecular Conformation;Morphogenesis;Motor;Mutation;Nerve Degeneration;neuropathology;Pattern;polyglycine;Positioning Attribute;Post-Translational Protein Processing;Process;Protein Isoforms;Recombinants;Regulation;Resolution;Retinal Diseases;single molecule;Site;Structure;Substrate Specificity;Tail;Techniques;three dimensional structure;Tubulin;Work;Writing;X-Ray Crystallography

PROJECT_TITLE: Mechanism of tubulin modification enzymes


NIH_SPENDING_CATS: Biotechnology;Neurosciences

PROJECT_TITLE: Readout of the tubulin code by cellular effectors


PROJECT_TERMS: Affect;alpha Tubulin;Architecture;ATP Hydrolysis;ATP phosphohydrolase;beta Tubulin;Biogenesis;Biological Process;Cells;Centrioles;Chromosome Segregation;Cilia;Code;combinatorial;Complex;Coupled;Crosslinker;Cryoelectron Microscopy;Cytoskeleton;dimer;Disease;Distal;Elements;Enzymes;Etiology;Excision;Exhibits;fluorescence imaging;functional outcomes;Genes;Hereditary Spastic Paraplegia;Human body;in vivo;insight;katanin;Mechanics;Microcephaly;Microtubules;Modification;Morphology;Mutate;Mutation;Neurodegenerative Disorders;Neurodevelopmental Disorder;Neurons;Pathway interactions;Phase;Phototropism;Polymerase;Post-Translational Protein Processing;protein function;protein structure;Proteins;Reaction;Regulation;response;Signal Transduction;single molecule;spastin;Structure;synergism;Tail;Tubulin;Work

PROJECT_TITLE: Mechanism of microtubule severing enzymes


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Genetics;Mental Health;Neurosciences;Schizophrenia

PI_NAMEs: GORDON, JOSHUA  (contact)

PROJECT_TERMS: 22q11.2;Adult;Affect;age related;Animals;Area;avoidance behavior;Behavior;Behavioral;Brain;Brain region;Cells;Chemosensitization;Cognition;Cognition Disorders;Cognitive deficits;cognitive function;cognitive process;Collaborations;Communication;Computer Models;confocal imaging;Cortical Synchronization;Data;data analysis pipeline;design;Disease;Distal;Dorsal;Electrodes;Electrophysiology (science);entorhinal cortex;Excitatory Synapse;Female;Fiber;Fostering;Frequencies;Functional disorder;Genetic Predisposition to Disease;Genotype;glycogen synthase kinase 3 beta;Goals;Heterozygote;Hippocampus;Human;Impaired cognition;Impairment;implantation;improved;in vivo;inhibitor;Interneurons;Lasers;learned behavior;Life;Light;Link;male;Medial;Mental disorders;Methods;microdeletion;Modeling;Molecular Target;Monitor;mouse model;Mus;Mutation;National Institute of Drug Abuse;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;neural;neural circuit;neurodevelopment;neuronal circuitry;Neurons;neurophysiology;Neurosciences;novel;null mutation;Optics;optogenetics;Output;Pathogenesis;Pathway interactions;Pattern;Performance;Periodicals;Phase;Phenotype;Photometry;Physiological;Population;Prefrontal Cortex;Process;Property;Protein Isoforms;Publishing;recruit;Reporting;Research;Resolution;response;Reuniens Thalamic Nucleus;Role;Route;Sampling;Schizophrenia;schizophrenia risk;sex;Shapes;Short-Term Memory;Signal Transduction;Somatostatin;stem;Structure;Synapses;Synaptic Transmission;Syndrome;Task Performances;Techniques;Testing;Thalamic structure;theories;Time;Tissues;tool;transcriptome sequencing;transcriptomics;Transgenic Organisms;Wild Type Mouse;Work

PROJECT_TITLE: Probing the neural circuit basis of normal and disease-relevant cognitive function in mice


NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Brain Disorders;Coronaviruses;Coronaviruses Therapeutics and Interventions;Emerging Infectious Diseases;Infectious Diseases;Neurosciences

PI_NAMEs: KORETSKY, ALAN  (contact)

PROJECT_TERMS: 2019-nCoV;Acceleration;Binding;Biological Assay;Blood - brain barrier anatomy;Blood capillaries;blood-brain barrier crossing;Brain;Brain Diseases;brain magnetic resonance imaging;contrast imaging;Contrast Media;Copper;cost;COVID-19 therapeutics;design;Detection;detection method;Development;Diagnosis;Diagnostic;dimer;Dose;drug discovery;Family;Funding;Goals;Health Sciences;Hour;Human;Human Resources;Image;imaging agent;improved;In Vitro;in vivo;Individual;Injections;Intramural Research Program;Intravenous;intravenous injection;Investigation;iron oxide nanoparticle;Joints;Kinetics;Laboratories;Lead;Magnetic Resonance Imaging;mathematical model;Methods;Modeling;Molecular;molecular modeling;molecular pathology;Mus;Mutant Strains Mice;nanobodies;National Institute of Neurological Disorders and Stroke;Nervous System Disorder;Neurologic;Neurosciences;novel therapeutics;Pathologic;Patients;Pharmacodynamics;Pharmacologic Substance;Positioning Attribute;Positron;Positron-Emission Tomography;Radiation exposure;Radiology Specialty;receptor;receptor binding;Regenerative Medicine;Reporting;Research Personnel;Research Project Grants;Resolution;response;Running;Signal Transduction;Site;Supervision;Testing;TFRC gene;therapeutic candidate;transcytosis;Transgenic Mice;United States National Institutes of Health;University Health Services;Visualization;Work

PROJECT_TITLE: Development of Brain MRI Contrast Agents


NIH_SPENDING_CATS: Genetics;Neurosciences

PI_NAMEs: HOLMGREN, MIGUEL  (contact)

PROJECT_TERMS: Axon;axoplasm;Cell Nucleus;Cells;Chemistry;Complex;Dendrites;Development;Diameter;Elements;Exhibits;fluorophore;Fucose;glycosylation;Goals;Homologous Gene;Human;In Vitro;Incubated;Injections;Libraries;Lipids;Maintenance;Membrane;Membrane Proteins;membrane synthesis;Messenger RNA;meter;Molecular;Neurons;next generation sequencing;Organelles;Process;Protein Biosynthesis;Protein Glycosylation;Proteins;Ribosomal RNA;RNA;RNA analysis;Sampling;seal;Signal Recognition Particle;Squid;squid axon;sugar;Synaptic plasticity;System;Translating;Translations;Work

PROJECT_TITLE: Membrane Protein synthesis in axons


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Brain Disorders;Dementia;Neurodegenerative;Neurosciences

PI_NAMEs: GU, YI  (contact)

PROJECT_TERMS: Alzheimer's Disease;Alzheimer's disease patient;Anatomy;Animals;Auditory;Behavioral;Brain;Calcium;cell type;Cells;Characteristics;Cognition;Collaborations;cortex mapping;Cues;educational atmosphere;entorhinal cortex;Environment;Exhibits;FOS gene;Foundations;Functional disorder;Future;Goals;Hippocampus;Image;imaging approach;Impairment;improved;insight;Laboratories;Learning;Link;Maintenance;Mammals;Manuscripts;Maps;Measurement;Medial;Memory impairment;Modality;Molecular;molecular dynamics;mouse model;multimodality;multisensory;Mus;National Institute of Mental Health;Nervous System Disorder;neural;neuromechanism;novel;Optics;optogenetics;Phase;preference;Process;Publishing;Recurrence;Research;Research Project Grants;Resolution;response;Retrieval;Sensory;Shapes;Solid;spatial memory;Synaptic plasticity;Tauopathies;Technology;Testing;Theoretical model;Time;tool;two-photon;Veronica;virtual;virtual environment;virtual reality;virtual reality environment;Visual;visual information;Visuospatial;way finding

PROJECT_TITLE: Neural mechanism of spatial navigation and memory


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Neurosciences

PI_NAMEs: ROLE, LORNA  (contact)

PROJECT_TERMS: Accounting;Acetylcholine;Address;Adult;Algorithms;Amygdaloid structure;Anterior;approach behavior;Aversive Stimulus;avoidance behavior;Axon;basal forebrain;Basal Nucleus of Meynert;Behavior;Behavioral;behavioral response;Bioinformatics;Biological Assay;Birth Order;Brain;cholinergic;cholinergic neuron;Code;Cognitive;cognitive function;Collaborations;Complex;Cues;Dependence;Desire for food;Development;Electrophysiology (science);Enrollment;entorhinal cortex;ERG gene;Extinction;forgetting;Genetic;Globus Pallidus;Goals;Heterogeneity;Hippocampus;Hour;Image;Immediate-Early Genes;Immunologics;in vivo;Label;Laboratories;Lateral;Learning;Limb structure;Location;Maps;Medial;member;Memory;memory encoding;memory retention;memory retrieval;Methods;Morphology;motivated behavior;National Institute of Neurological Disorders and Stroke;neural;Neurons;Neurosciences;Odors;optogenetics;performance tests;Phase;Physiology;Population;postsynaptic;Prefrontal Cortex;presynaptic;prevent;Property;Prosencephalon;Publications;recruit;Reporting;Research;response;Rest;Role;sensor;Shapes;Shock;Signal Transduction;Site;Source;Stimulus;Substantia Innominata;Synapses;System;Training;Viral Vector;Weight;Work

PROJECT_TITLE: Acetylcholine in learning and memory


NIH_SPENDING_CATS: Brain Cancer;Brain Disorders;Cancer;Cerebrovascular;Clinical Research;Neurosciences;Orphan Drug;Rare Diseases

PI_NAMEs: JACKSON, SADHANA  (contact)

PROJECT_TERMS: Adult;Agonist;Animal Model;Blood - brain barrier anatomy;blood-brain barrier permeabilization;Brain;Brain region;brain tissue;Cells;chemotherapeutic agent;Child;Clinic;Clinical Research;Communication;contrast enhanced;Contrast Media;Endothelium;experimental study;G-Protein-Coupled Receptors;Glioma;Goals;Growth;hematopoietic stem cell self-renewal;Image;In Vitro;Invaded;Investigation;Investigational Therapies;Laboratories;Malignant Glioma;Malignant neoplasm of brain;Measures;Mediator;Microdialysis;novel;Pathway interactions;Penetration;Perfusion;Permeability;Pharmaceutical Preparations;pharmacologic;Proliferating;Proto-Oncogene Proteins c-akt;Research;Signal Pathway;standard measure;Study models;Tight Junctions;Time;treatment response;tumor;tumor microenvironment;Tumor Tissue

PROJECT_TITLE: Modulating BBB Permeability in Malignant Glioma


NIH_SPENDING_CATS: Brain Cancer;Brain Disorders;Cancer;Clinical Research;Immunotherapy;Neurosciences;Rare Diseases

PI_NAMEs: NDUOM, EDJAH  (contact)

PROJECT_TERMS: Address;Adult;Affinity;Aftercare;American;Animals;anti-PD-L1 antibodies;anti-tumor immune response;Attitude;Biological Markers;Biological Models;Biology;biomarker development;Biopsy;Brain;Brain Neoplasms;Cell Line;Cells;Central Nervous System Neoplasms;Cerebrum;Clinical;clinical investigation;Clinical Research;Congresses;cytokine;Data;Data Collection;design;diffuse midline glioma;Enrollment;Evaluation;Future;Genetic Transcription;Glioblastoma;Glioma;Goals;Immune;immune checkpoint blockade;Immune checkpoint inhibitor;immune modulating agents;Immune response;Immunocompetent;Immunologic Monitoring;immunoregulation;Immunosuppression;Immunotherapeutic agent;Immunotherapy;Implant;insight;International;Investigation;Investments;Joints;Journals;Knowledge;Learning;Lesion;Luciferases;Malignant Neoplasms;Manuscripts;meetings;member;meningioma;Microdialysis;Modeling;mouse model;Mus;Myeloid Cells;Natural Killer Cells;neuro-oncology;Neurologic;Neurology;Neurosurgeon;neurosurgery;novel strategies;Operative Surgical Procedures;Patients;Pattern;Protocols documentation;Publishing;rare cancer;Reaction;Reporting;Sampling;Societies;Source;Surgeon;Surveys;Technology;Therapy trial;Time;Translational Research;tumor;tumor immunology;tumor microenvironment;tumor-immune system interactions;Untranslated RNA;Variant;Work

PROJECT_TITLE: Clinical and Translational Investigations of Immune Suppression and Immune Modulation in Glioblastoma


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Disability Research;Genetics;Neurosciences

PI_NAMEs: SHEIKHBAHAEI, SHAHRIAR  (contact)

PROJECT_TERMS: Adult;Affect;Animal Behavior;Animal Vocalization;Animals;Area;Attention deficit hyperactivity disorder;autism spectrum disorder;Behavior;Behavioral;Biological;Brain;brain iron;Breathing;Cells;Central Nervous System;Communication;Complex;Data;Defect;Development;Developmental Stuttering;Disease;disorder control;Economics;Electrophysiology (science);Ethnic Origin;experimental study;Functional disorder;gene discovery;Generations;Genes;Genetic;Goals;Hereditary Disease;Histology;Homeostasis;Human;Image;Impairment;improved;In Vitro;in vivo Model;Investigation;Iron Chelation;Link;Maps;motor behavior;motor control;motor disorder;mouse model;Movement;Muscle;mutant;Mutate;Nervous System;neural;neural correlate;Neurodegenerative Disorders;Neurodevelopmental Disorder;Neuroglia;Neurologic;Neurons;neurotransmission;novel;novel therapeutics;Oligodendroglia;operation;Optical Methods;Parkinson Disease;Pathway interactions;Persons;Play;Population;preclinical study;Process;Production;programs;Property;Race;Reporting;Research;Rodent;skills;Sleep;Speech;Stuttering;Subgroup;Synapses;System;Techniques;Therapeutic Agents;tool;Transgenic Animals;Viral Vector;vocal control;vocalization;white matter

PROJECT_TITLE: Neural correlates for cortical and subcortical control of vocalization


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Dementia;Neurodegenerative;Neurosciences

PROJECT_TERMS: Address;Affect;Age;Age Months;age related;age related changes;age related deterioration;Age-associated memory impairment;aged;Aging;aging process;Alzheimer's Disease;animal old age;Animals;Anterior;Area;Axon;basal forebrain;basal forebrain cholinergic neurons;Behavior;Behavioral Assay;Binding;biocytin;Biological Assay;Body Regions;Callithrix;Cell Nucleus;Cells;Cessation of life;cholinergic;cholinergic neuron;Cognition;Cognitive;Cognitive deficits;cognitive performance;cognitive task;Collaborations;comparative;Comparative Study;Complex;Cues;Dementia;density;Electrophysiology (science);Emotional;Enhancers;entorhinal cortex;Event;experience;Face;Fright;Frontotemporal Dementia;Functional disorder;Gene Expression;Gene Modified;Genes;Genetic;Goals;Health;Hippocampus;Human;Impaired cognition;Impairment;in vivo;Individual;juvenile animal;Knowledge;Label;Lateral;learned behavior;Learning;life span;Link;Literature;loved ones;Macaca;Memory;Memory Loss;memory recall;Methods;Microglia;Microtus;mild cognitive impairment;Mitochondria;mitochondrial dysfunction;Modeling;Molecular;Monkeys;Morphology;mouse model;Mus;Mutant Strains Mice;Nerve Degeneration;nerve supply;Neurodegenerative Disorders;Neurons;Neurosciences;normal aging;novel;object recognition;old mice;Parkinson Disease;Participant;Pathologic;pathological aging;Pathology;Pattern;Performance;Population;Positron-Emission Tomography;Predisposition;presynaptic;Presynaptic Terminals;Process;programs;Protocols documentation;reconstruction;Recycling;Research;Research Personnel;resilience;Rodent;Role;sex;Signal Transduction;single nucleus RNA-sequencing;Site;Social Interaction;Sorting;Stains;Subgroup;System;tau-1;Temporal Lobe;Testing;Time;Tissues;transcriptomics;ultra high resolution;Vesicle;Virus;Work;young adult

PROJECT_TITLE: The cholinergic system during normal and pathological aging


NIH_SPENDING_CATS: Biotechnology;Genetics;Human Genome;Neurosciences;Regenerative Medicine;Stem Cell Research;Stem Cell Research - Nonembryonic - Non-Human

PI_NAMEs: NGAI, JOHN  (contact)

PROJECT_TERMS: Ablation;Acute;Adult;adult neurogenesis;Afferent Neurons;Area;ATAC-seq;Axon;Basal Cell;beta catenin;Candidate Disease Gene;candidate identification;candidate validation;Cell Culture Techniques;Cell Differentiation process;Cell Proliferation;Cell Survival;Cells;Chromatin;Chromium;conditional knockout;Data;data analysis pipeline;Dependovirus;Development;Devices;Environment;Epidermal Growth Factor Receptor;Epigenetic Process;Epithelium;epithelium regeneration;Expression Library;fluorescence activated cell sorter device;Fluorescent in Situ Hybridization;gain of function;Gene Expression;gene regulatory network;Generations;Genes;Genetic;genetic analysis;Genetic Transcription;genetically modified cells;Gland;Goals;Heterogeneity;high throughput analysis;Hour;In Vitro;in vitro Model;in vivo;Individual;injured;Injury;interest;Knock-out;Learning;Libraries;Life;loss of function;Maintenance;Manuscripts;Metaplasia;migration;Modeling;Molecular;Molecular Neurobiology;mouse model;multiple omics;Multipotent Stem Cells;Mus;Natural regeneration;Nerve Regeneration;nerve stem cell;Nervous System;neural;Neurons;neuroregulation;Olfactory Epithelial Cell;Olfactory Epithelium;olfactory neurogenesis;Olfactory Pathways;Olfactory Receptor Neurons;overexpression;Pathway interactions;Plasmids;Population;postnatal;Preparation;Printing;progenitor;programs;Proliferating;Property;reconstitution;Regenerative capacity;Reporter;RNA;Role;Sensory;sensory mechanism;Signal Pathway;Signal Transduction;single cell sequencing;single nucleus RNA-sequencing;Specific qualifier value;Statistical Data Interpretation;stem cell function;stem cell proliferation;stem cells;sustentacular cell;Synapses;Testing;Tissues;transcription factor;transcriptome sequencing;Transfection;United States National Institutes of Health;Veins;virtual;WNT Signaling Pathway

PROJECT_TITLE: Elucidating the molecular mechanisms of sensory regeneration


NIH_SPENDING_CATS: Brain Disorders;Genetics;Human Genome;Mental Health;Neurosciences

PI_NAMEs: TALMAGE, DAVID  (contact)

PROJECT_TERMS: Acetylcholine;Acute;adult neurogenesis;Affect;age related;Age-associated memory impairment;Alzheimer's Disease;Animals;ATAC-seq;Attention;Axon;axon growth;basal forebrain;Behavior;behavior influence;Behavioral;Biological Process;Birth;Brain;Brain region;Cell Nucleus;Cells;Central Nervous System;Cessation of life;cholinergic;cholinergic neuron;Chromatin;Code;Collaborations;Complex;Cytoplasmic Granules;Data;Data Set;Dendrites;dentate gyrus;Development;differential expression;Diffuse;Essential Genes;Event;experimental study;Family;flexibility;follow-up;Functional disorder;Gene Dosage;Gene Expression;gene network;Generations;Genes;Genetic;Genetic Markers;Genetic Transcription;Globus Pallidus;Glutamates;granule cell;Growth;Heterogeneity;Heterozygote;Hippocampus;Homozygote;Human;imaging study;Impaired cognition;In Vitro;in vivo;Individual;Informatics;insight;interest;Intervention;Investigation;Journals;Learning;loss of function mutation;Maintenance;Maps;Membrane;Memory;Mental disorders;Minor;Mitochondria;Modeling;Molecular;multiple omics;Mus;mutant;Mutation;Negative Valence;Nervous System;nervous system development;neural circuit;Neuregulin 1;Neurodegenerative Disorders;neurogenesis;Neurons;neuropsychiatric disorder;Neurosciences;neurotransmission;Nicotine;NRG1 gene;Nuclear;Odors;Parkinson Disease;Phenotype;Physiological;Polycomb;Population;Positioning Attribute;Post-Traumatic Stress Disorders;postnatal;Preparation;presynaptic;Prosencephalon;Protein Biosynthesis;Protein Isoforms;Regulation;Reporting;Repressor Proteins;Research;resilience;response;Retrieval;Role;scaffold;Schizophrenia;Series;Signal Transduction;Signaling Protein;single nucleus RNA-sequencing;Site;Structure;Synapses;synaptic function;Synaptic plasticity;synaptogenesis;synergism;System;targeted treatment;Testing;Time;Tissues;trafficking;transcriptome;transcriptome sequencing;transcriptomics;Transmembrane Domain;Wild Type Mouse;young adult

PROJECT_TITLE: Molecular signaling during development and maturation of the nervous system


NIH_SPENDING_CATS: Biomedical Imaging;Brain Disorders;Clinical Research;Emerging Infectious Diseases;Immunotherapy;Infectious Diseases;Neurodegenerative;Neurosciences;Rare Diseases

PI_NAMEs: CORTESE, IRENE  (contact)

PROJECT_TERMS: Address;Affect;Autopsy;biomarker validation;Brain;Cells;Cerebrospinal Fluid;checkpoint inhibition;Clinical;cohort;Collaborations;Collection;Core Facility;Coupled;cytokine;Data;Depressed mood;Disease;disorder control;Enrollment;experience;Functional disorder;Goals;healthy volunteer;Histologic;Homeostasis;IL7 gene;Image;Immune;immune reconstitution;Immune response;Immune system;Immunologics;Immunology;Immunosuppression;Immunotherapeutic agent;in vitro Assay;Infection;Integration Host Factors;Intervention;Intervention Studies;JC Virus;Life;Magnetic Resonance Imaging;Mediating;Molecular;National Institute of Neurological Disorders and Stroke;Natural History;Nature;Organ;Outcome;Outcome Measure;Participant;participant enrollment;patient population;Patients;Peripheral Blood Mononuclear Cell;pharmacologic;Plasma;Predisposition;Progressive Multifocal Leukoencephalopathy;Radiology Specialty;Recombinants;reconstitution;Recovery;Reporting;Risk;risk minimization;Schedule;Serum;Standardization;systemic autoimmune disease;T-Lymphocyte;Testing;Time;Tissue Banks;translational study;Translations;treatment response;treatment strategy;Viral;Virus Diseases;virus host interaction

PROJECT_TITLE: Translational Studies in Progressive Multifocal Leukoencephalopathy


NIH_SPENDING_CATS: Biomedical Imaging;Brain Disorders;Clinical Research;Epilepsy;Mental Health;Neurodegenerative;Neurosciences

PI_NAMEs: INATI, SARA  (contact)

PROJECT_TERMS: Address;Anterior;Area;arterial spin labeling;blood perfusion;Brain;brain abnormalities;Cerebrovascular Circulation;Child;Clinical;Clinical assessments;cohort;Collaborations;Core Facility;Cortical Dysplasia;Data;Detection;Diffusion Magnetic Resonance Imaging;Distant;Drug resistance;effective therapy;Electrodes;Electroencephalography;Epilepsy;epileptiform;Evaluation;Excision;Family;Functional disorder;Functional Magnetic Resonance Imaging;Goals;healthy volunteer;Hippocampus;Hour;hypoperfusion;Image;image processing;imaging biomarker;imaging modality;imaging study;improved;indexing;individual patient;Intervention;invention;Ipsilateral;Knowledge;Language;Lateral;Magnetic Resonance Imaging;Magnetoencephalography;Manuscripts;Masks;Measures;Medial;medial temporal lobe;Medical center;Memory;Methods;Modeling;Morbidity - disease rate;mortality;National Institute of Neurological Disorders and Stroke;Neocortex;neuroimaging;neurophysiology;Neuropsychological Tests;Neuropsychology;non-invasive imaging;novel;novel marker;Operative Surgical Procedures;Outcome;Paper;Parahippocampal Gyrus;Partial Epilepsies;Patients;Pattern;Perfusion;posters;Postoperative Period;Preparation;productivity loss;prospective;psychosocial;Publishing;Research;Rest;Sampling;Sclerosis;Seizures;social stigma;Source;source localization;Structural defect;Structure;Surface;Temporal Lobe;Temporal Lobe Epilepsy;temporal measurement;Time;Tissues;tool;Travel;white matter;Work

PROJECT_TITLE: Investigating Epileptic and Functional Networks in Patients with Drug Resistant Focal Epilepsy


NIH_SPENDING_CATS: Brain Cancer;Brain Disorders;Cancer;Clinical Research;Immunotherapy;Neurosciences;Radiation Oncology;Rare Diseases

PI_NAMEs: BROWN, DESMOND  (contact)

PROJECT_TERMS: Apical;Bioinformatics;Biological Assay;Cell Cycle;Cell Line;cell motility;Cell Proliferation;Cells;Characteristics;chemoradiation;Cilia;cilium biogenesis;clinically relevant;Development;Disease;Excision;extracellular vesicles;Gene Expression;Genes;Glioblastoma;Glioma;Goals;Human;Immunosuppression;Immunotherapy;Impairment;Interleukin-6;knock-down;Malignant neoplasm of brain;Malignant Neoplasms;Mammalian Cell;Mediating;Microtubules;Molecular;Morphology;Myeloid-derived suppressor cells;neurosurgery;Newly Diagnosed;novel;novel therapeutics;Oncology;Organelles;particle;Pathogenesis;Pathway interactions;Patients;Play;Prognostic Marker;Proliferating;Proteins;public database;Radiation therapy;Regulation;Resistance;response;Role;Signal Pathway;Signal Transduction;stable cell line;standard of care;Surface;temozolomide;tumor;Tumor-Derived;Update;Work;wound healing

PROJECT_TITLE: Neurosurgical Oncology Unit


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Neurosciences

PI_NAMEs: WAGNER, MARK  (contact)

PROJECT_TITLE: Neocortex-cerebellum Circuitry Unit


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease Related Dementias (ADRD);Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Behavioral and Social Science;Brain Disorders;Cerebrovascular;Clinical Research;Dementia;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Neurodegenerative;Neurosciences;Prevention;Social Determinants of Health;Stroke;Vascular Contributions to Cognitive Impairment and Dementia (VCID)

PI_NAMEs: GOTTESMAN, REBECCA F (contact)

PROJECT_TERMS: Atherosclerosis Risk in Communities;Blood Vessels;blood-based biomarker;Brain;brain health;Brain hemorrhage;Brain Injuries;CADASIL;Cerebral small vessel disease;Cerebrovascular Disorders;Clinical Protocols;Cognition;Cognitive;cognitive change;cognitive performance;cohort;Collaborations;Complement;Dementia;Disease;Disparity;disparity reduction;epidemiology study;Etiology;Evaluation;experience;Extramural Activities;Funding;Future;General Population;Genes;Goals;Health;Hemorrhage;High Prevalence;Human;imaging biomarker;Impaired cognition;Individual;Infarction;Inherited;Intervention;Intramural Research Program;Ischemic Stroke;Life Cycle Stages;Measurement;Methods;Microvascular Dysfunction;middle age;modifiable risk;National Institute of Neurological Disorders and Stroke;Neuroepidemiology;neuroimaging;Outcome;Pathway interactions;Pattern;Population Study;post stroke;post stroke cognitive impairment;Prevention;Recovery;Recurrence;Risk;Risk Factors;Role;social health determinants;Stroke;United States National Institutes of Health;vascular cognitive impairment and dementia;Vascular Diseases;vascular risk factor

PROJECT_TITLE: Stroke, Cognition and Neuroepidemiology Section


PI_NAMEs: NATH, AVINDRA  (contact)

PROJECT_TERMS: Address;Algorithms;Anti-Retroviral Agents;Autopsy;Bar Codes;Bioinformatics;Biological Assay;Brain;Cell Extracts;Cell Line;Cells;Consensus;Data;Data Analyses;design;Detection;Devices;digital;DNA;DNA Fragmentation;DNA Library;DNA Probes;DNA sequencing;Endogenous Retroviruses;Environment;Evolution;frontal lobe;genetic evolution;Genomic DNA;Genomics;Globus Pallidus;Goals;Hippocampus;HIV;HIV Genome;Human Genome;improved;Infection;integration site;Jurkat Cells;Length;Liver;lymph nodes;Lymphoid;Lymphoid Tissue;Methods;Molecular;nanopore;National NeuroAids Tissue Consortium;next generation sequencing;novel strategies;Patients;Penetration;Peripheral;Persons;Pharmaceutical Preparations;Process;protein expression;Protocols documentation;Proviruses;RNA;Running;Sampling;sequencing platform;single molecule;Site;Spleen;Techniques;Thalamic structure;therapy design;Tissues;transcriptomics;Tube;Variant;Viral;Viral Genes;Viral Proteins;Viral reservoir;Virus Integration

PROJECT_TITLE: Characterization of HIV Reservoirs in the Brain


NIH_SPENDING_CATS: Bioengineering;Neurosciences

PI_NAMEs: ROLL-MECAK, ANTONINA  (contact)

PROJECT_TERMS: alpha Tubulin;Antibodies;Award;beta Tubulin;cell type;cellular imaging;Chemicals;Code;Communication;Coupled;Environment;Human;Image;imaging modality;improved;Induced pluripotent stem cell derived human neuron;Life;Maps;Mechanics;Methods;Microscope;Microscopy;Microtubule-Associated Proteins;Microtubules;Modification;Molecular;molecular imaging;Motor;nanoscale;National Institute of Biomedical Imaging and Bioengineering;National Institute of Neurological Disorders and Stroke;Neurons;Polymers;Post-Translational Protein Processing;Process;Protocols documentation;Reader;recruit;Resolution;Sampling;single molecule;Tubulin

PROJECT_TITLE: 4D map of the tubulin code in the human neuron


NIH_SPENDING_CATS: Biotechnology;Brain Disorders;Clinical Research;Emerging Infectious Diseases;Genetics;HIV/AIDS;Human Genome;Infectious Diseases;Neurodegenerative;Neurosciences

PI_NAMEs: JACOBSON, STEVEN  (contact)

PROJECT_TERMS: Address;Antibodies;Antigens;B-Cell Antigen Receptor;B-Lymphocytes;Blood;Brain;CD8-Positive T-Lymphocytes;Cells;Cerebrospinal Fluid;Chromium;Clinical;Clonal Expansion;Clonality;Clone Cells;cohort;complementarity-determining region 3;Complementary DNA;Coupled;deep sequencing;Detection;Disease;Disease Progression;Dissection;DNA;Evaluation;Evolution;exhaustion;Frequencies;Gene Expression Profiling;Genomics;HIV;HIV Infections;HIV-associated neurocognitive disorder;Human T-lymphotropic virus 1;Immune;Immune response;Immunologic Memory;Individual;Infiltration;inflammatory milieu;Laboratories;lymphoid organ;Macrophage;Meninges;neuroAIDS;neuroinflammation;Neurologic;Open Reading Frames;Pathogenesis;Pathogenicity;Patients;Peripheral Blood Mononuclear Cell;Persons;Post-Acute Sequelae of SARS-CoV-2 Infection;Process;Reporting;response;Sequence Analysis;single cell sequencing;single-cell RNA sequencing;T-Cell Immunologic Specificity;T-Cell Receptor;T-cell receptor repertoire;T-Lymphocyte;Technology;Time;tool;treatment response;United States National Institutes of Health;Viral;Viral reservoir;Virus

PROJECT_TITLE: Single Cell RNA Sequencing of Blood and CSF of Patients with NeuroAIDS


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Aging;Alzheimer's Disease;Alzheimer's Disease Related Dementias (ADRD);Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Brain Disorders;Clinical Research;Dementia;Frontotemporal Dementia (FTD);Neurodegenerative;Neurosciences;Rare Diseases

PI_NAMEs: KWAN, JUSTIN  (contact)

PROJECT_TERMS: Address;Age;Age of Onset;Alzheimer's Disease;Alzheimer's disease related dementia;American;Biological;brain magnetic resonance imaging;C9ORF72;Clinic;Clinical;Clinical Data;clinical diagnosis;Clinical Trials;cognitive testing;Collection;Communities;Data Collection;data sharing;Development;Disease;DNA-Binding Proteins;effective therapy;Enrollment;Evaluation;Familial disease;Family;follow-up;Fostering;frontotemporal degeneration;Frontotemporal Dementia;Frontotemporal Lobar Degenerations;Genes;Goals;improved;Individual;Infrastructure;Inherited;Institutional Review Boards;MAPT gene;meetings;Molecular Weight;Mutation;Neurodegenerative Disorders;Neurologist;Participant;participant enrollment;Patients;PGRN gene;Physicians;Procedures;programs;protein aggregation;Protocols documentation;Questionnaires;Recommendation;Recording of previous events;recruit;Research;Research Personnel;Research Project Grants;Sampling;Scanning;Schedule;Scientist;Series;Site;Study Subject;Syndrome;tau Proteins;Testing;United States National Institutes of Health

PROJECT_TITLE: ALLFTD: ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration


NIH_SPENDING_CATS: Brain Disorders;Clinical Research;HIV/AIDS;Infectious Diseases;Neurodegenerative;Neurosciences;Rare Diseases

PROJECT_TERMS: Address;Algorithms;Alleles;biobank;blood product;cell bank;Cell Line;Cells;Characteristics;cohort;Databases;Development;effective therapy;Ensure;healthy volunteer;Immune;In Vitro;Life Expectancy;manufacture;Methods;Natural History;Outcome;Participant;Patients;Pilot Projects;Progressive Multifocal Leukoencephalopathy;Research;Source;T-Lymphocyte;Time;treatment strategy;United States National Institutes of Health;Viral Physiology;Virus;Work

PROJECT_TITLE: Establishing a JCV specific T cell bank for progressive multifocal leukoencephalopathy


PI_NAMEs: STEINER, JOSEPH  (contact)

PROJECT_TERMS: Amino Acids;antagonist;antiretroviral therapy;Biodistribution;Biological Assay;Biological Products;brain tissue;Calcium;CCL2 gene;CCL3 gene;Cell Nucleus;Cells;Cerebrospinal Fluid;Detection;Development;Drug Kinetics;Genetic Transcription;glial activation;Goals;HIV;HIV Infections;HIV Long Terminal Repeat;innovation;Interleukin-6;Lead;Long Terminal Repeats;N-Methyl-D-Aspartate Receptors;neurotoxic;Oxidative Stress;Patients;Peripheral Blood Mononuclear Cell;Pharmacodynamics;Production;Promoter Regions;Property;Proteins;Role;T-Lymphocyte;tat Protein;Tissue Sample;TNF gene;Trans-Activators;Transactivation;Transcript;Transcription Coactivator;Transcriptional Activation;United States National Institutes of Health;Viral Load result;Virus;Virus Diseases;Virus Replication

PROJECT_TITLE: Development of Tat antagonists to achieve a functional cure for HIV infection


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Alzheimer's Disease Related Dementias (ADRD);Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Bioengineering;Biomedical Imaging;Brain Disorders;Cerebrovascular;Dementia;Neurodegenerative;Neurosciences;Stroke;Vascular Contributions to Cognitive Impairment and Dementia (VCID)

PI_NAMEs: MUGHAL, AMREEN  (contact)

PROJECT_TERMS: 3-Dimensional;Animals;Arteries;arteriole;Attention;Blood;Blood capillaries;Blood Vessels;Brain;Brain Diseases;brain parenchyma;Breeding;Cells;cerebral blood volume;cerebral hemodynamics;cerebral vein;Cerebrovascular Circulation;Communication;Complex;Consumption;Data Set;density;Diamond;Electron Microscope;Electrophysiology (science);Endothelial Cells;Endothelium;Equipment;Excision;experimental study;Functional Magnetic Resonance Imaging;Genotype;Goals;Homeostasis;Human;Impairment;in vivo;instrumentation;Investments;Ion Channel;Lasers;learning progression;Light;material transfer agreement;Measurement;member;Metabolic;Microscope;Microvascular Dysfunction;Modeling;Molecular Target;mouse model;multiphoton microscopy;Mus;Myography;Neuroglia;Neurons;neurovascular coupling;neurovascular unit;Nutrient;operation;patch clamp;Pathologic;Pathway interactions;Penetration;Permeability;Pial Veins;Postbaccalaureate;Postdoctoral Fellow;pressure;prevent;Process;programs;Protocols documentation;Regulation;Research;Resistance;Rest;Stroke;Subarachnoid Hemorrhage;summer student;Therapeutic Intervention;Time;ultrasound;Universities;Vascular blood supply;vascular cognitive impairment and dementia;Vascular Dementia;Venous;venule;Vermont;Visual Cortex;wasting;Work

PROJECT_TITLE: Neurovascular Coupling and Brain Homeostasis


ACTIVITY: ZIC

ADMINISTERING_IC: DE

IC_NAME: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH

NIH_SPENDING_CATS: Dental, Oral, and Craniofacial Disease

PI_NAMEs: WANG, YAN  (contact)

PROJECT_TERMS: bioinformatics tool;Chromatography;Collaborations;Complex;Consultations;data acquisition;Data Analyses;Mass Spectrum Analysis;method development;Molecular Weight;National Institute of Dental and Craniofacial Research;Phosphorylation;Post-Translational Protein Processing;Preparation;protein profiling;Proteins;Proteomics;Research Personnel;Sampling;Services;Technology;Ubiquitination

PROJECT_TITLE: Mass Spectrometry Facility


ADMINISTERING_IC: MH

IC_NAME: NATIONAL INSTITUTE OF MENTAL HEALTH

NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Clinical Research;Mental Health;Neurosciences

ORG_NAME: NATIONAL INSTITUTE OF MENTAL HEALTH

PI_NAMEs: BANDETTINI, PETER  (contact)

PROJECT_TERMS: Acoustic Stimulation;Address;Administrator;American College of Radiology;Anisotropy;Archives;Area;Auditory system;Book Chapters;Boston;Brain;Budgets;Characteristics;Chronology;clinical center;Collaborations;Communities;Computer software;Core Facility;Data;data acquisition;Data Storage and Retrieval;Dedications;Deposition;Development;Devices;Disasters;education resources;Electroencephalography;Electronics;Elements;Encyclopedias;Environment;Equipment;Event;Excision;experience;Experimental Designs;experimental study;Floor;Friends;Functional disorder;Functional Magnetic Resonance Imaging;functional magnetic resonance imaging/electroencephalography;Galvanic Skin Response;Goals;Group Meetings;Hearing;hemodynamics;high resolution imaging;Holly;Hour;Human;Human Experimentation;Hybrids;Image;Individual;Industry;Inflammation;Infrastructure;Institutional Review Boards;instrumentation;Interest Group;International;Intramural Research Program;Investigational Therapies;Iron;Joystick;lectures;Linux;Location;Magnetic Resonance Imaging;Maintenance;Medical;medical specialties;Metabolic;Metadata;Methodology;Methods;millisecond;Modeling;Modernization;Morphologic artifacts;Motion;multimodal neuroimaging;Myelin;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;National Institute on Alcohol Abuse and Alcoholism;neural;neurofeedback;neuroimaging;Neurology;Neurons;Neurosciences;neurotransmission;Noise;novel;Nurse Practitioners;open source;Operating System;pandemic disease;Performance;Peripheral;petabyte;Phase;Physics;Physiologic pulse;Physiological Processes;Principal Investigator;prisma;procedure safety;Productivity;Protocols documentation;Publishing;quality assurance;radio frequency;Radiology Specialty;reconstruction;Research;Research Personnel;Research Support;Resolution;Resources;Role;Scanning;Schedule;Scientist;Series;Services;Site;skills;Somatosensory Cortex;spatiotemporal;Specialist;symposium;System;Techniques;Technology;Testing;Time;tool;Training;Transcranial magnetic stimulation;Translating;transmission process;ultra high resolution;United States National Institutes of Health;Update;Vendor;virtual;virtual machine;Visual Cortex;visual tracking;web site;white matter;Work

PROJECT_TITLE: Functional MRI Core Facility


NIH_SPENDING_CATS: Alcoholism, Alcohol Use and Health;Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Brain Disorders;Conditions Affecting the Embryonic and Fetal Periods;Fetal Alcohol Spectrum Disorders (FASD);Intellectual and Developmental Disabilities (IDD);Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences;Pediatric;Perinatal Period - Conditions Originating in Perinatal Period;Substance Misuse

PI_NAMEs: TAYLOR, PAUL  (contact)

PROJECT_TERMS: Age;Agreement;alcohol exposure;algorithm development;Algorithms;analytical method;Anatomy;animal data;anxiety symptoms;Area;Arithmetic;Atlases;Autopsy;Basic Science;Blood;Brain;Brain imaging;Brain region;Breathing;Canis familiaris;Child;Collaborations;college;Complex;Computer software;Computer Systems;computerized data processing;Consult;Consultations;Coronavirus;Correlation Studies;Data;Data Analyses;data handling;data quality;Data Set;Deep Brain Stimulation;design;Development;Diffusion;Diffusion Magnetic Resonance Imaging;Disease;Dryness;Education;Educational process of instructing;Engineering;Experimental Designs;experimental study;Fetal Alcohol Exposure;Fetal Alcohol Spectrum Disorder;flexibility;Functional Magnetic Resonance Imaging;functional MRI scan;Future;genetic information;gigabyte;Goals;Head;Heart Rate;Heritability;Hour;Human Activities;human data;Image;image warping;imaging study;improved;Institution;interest;Korea;learning materials;Linux;Literature;magnetic field;Magnetic Resonance Imaging;Maps;Measures;medical schools;meetings;member;Mental Depression;Methodology;Methods;Mexico;Mission;Modeling;Morphologic artifacts;Motion;National Institute of Mental Health;neurofeedback;neuroimaging;Neurons;Noise;Online Systems;open source;Output;Panic;Paper;Participant;Pathway interactions;Patients;Pattern;Performance;Persons;Photography;Physiological;Process;programs;Psyche structure;Public Health;Publications;Publishing;Quality Control;Reading;reading ability;repetitive transcranial magnetic stimulation;Reporting;Research;Research Personnel;Research Project Grants;research study;responders and non-responders;response;Rest;Sampling;Scanning;scientific computing;Slide;social;Societies;software development;Software Tools;Source Code;South Carolina;Statistical Computing;Statistical Data Interpretation;Techniques;Technology;Text;Time;Time Series Analysis;tool;Training;trait;Twin Studies;United States National Institutes of Health;Update;Vision;Visualization;web site;white matter;Work

PROJECT_TITLE: Scientific and Statistical Computing Core


NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Clinical Research;Data Science;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: NUGENT, ALLISON  (contact)

PROJECT_TERMS: Acceleration;Address;Algorithms;analysis pipeline;analytical method;Area;Auditory;Bathing;Brain;Brain imaging;BRAIN initiative;Calibration;Canada;Clinical;Code;Cognitive;cognitive task;Collaborations;combat;Communities;Compensation;Complex;Computer software;computerized data processing;Consultations;Core Facility;cortex mapping;COVID-19 pandemic;Custom;Data;data acquisition;Data Analyses;Data Analytics;Data Collection;data harmonization;data repository;Data Science;Data Set;data sharing;data standards;Data Storage and Retrieval;data structure;Dedications;deep neural network;design;Development;Devices;Disease;Educational process of instructing;Educational workshop;Electrocorticogram;Electrodes;Elements;Ensure;Equipment;Equipment Malfunction;Experimental Designs;Extramural Activities;falls;Functional Magnetic Resonance Imaging;Funding;Future;Genomics;Genotype;Goals;Grant;hackathon;Head;Health;Helium;High Performance Computing;Hour;Human;human data;human subject;Image;improved;Individual;Industry;industry partner;instrumentation;International;Journals;Knowledge;Liquid substance;magnetic field;Magnetic Resonance Imaging;Magnetism;Magnetoencephalography;Manuscripts;Maps;Measurement;Measures;meetings;Meta-Analysis;Methods;Mission;Modeling;Morphologic artifacts;National Institute of Mental Health;Neural Network Simulation;neuroimaging;Neurons;neurophysiology;neuropsychiatric disorder;North America;novel;open source;Optics;Participant;Patients' Rooms;Phenotype;pilot test;Positioning Attribute;posters;Preparation;Procedures;Process;programs;Protocols documentation;Pump;Pythons;reconstruction;recruit;Research;research and development;Research Personnel;Resolution;Resource Sharing;response;Response to stimulus physiology;Scalp structure;Scanning;Scientist;sensor;Signal Transduction;simulation;software development;somatosensory;Source;Stimulus;superconducting quantum interference device;Surface;Suspensions;symposium;System;Techniques;Temperature;Testing;Time;Training;Training and Education;United States National Institutes of Health;Universities;volunteer;Weight;Work;working group;Writing

PROJECT_TITLE: NIMH MEG Core Facility


NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Mental Health;Neurosciences

PI_NAMEs: SHEN, JUN  (contact)

PROJECT_TERMS: Acceleration;Acetates;Adopted;Alzheimer's Disease;Area;Basic Science;beta-Hydroxybutyrate;Binding;Biochemical;Biopsy;Brain;Carbon;Cerebrum;Chemical Shift Imaging;Chemicals;Choline;Clinical;Clinical Research;Clinical Sciences;Collaborations;Computer software;computerized data processing;Core Facility;Coupling;Creatine;Data;data acquisition;Data Analyses;Detection;detection method;Development;Dimensions;Dipeptides;Disease;Ensure;enzyme activity;experimental study;frontal lobe;Functional Imaging;gamma-Aminobutyric Acid;Glucose;glutamatergic signaling;Glutamates;Glutamine;Glutathione;Goals;Hospitals;Human;Image;imaging modality;imaging study;Imaging Techniques;improved;Individual;interest;Intravenous infusion procedures;invention;ketogenic diet;Label;macromolecule;magnetic field;Magnetic Resonance Imaging;Magnetic Resonance Spectroscopy;Maintenance;Manufacturer;Maps;Measurement;Measures;Mental disorders;metabolic profile;Methods;Motion;Movement;N-acetylaspartate;N-acetylaspartylglutamate;National Institute of Neurological Disorders and Stroke;Nervous System Disorder;neurochemistry;Neurons;Neurotransmitters;Noise;novel;Occipital lobe;Oxidative Stress;Participant;Pathway interactions;phase change;Phosphorus;Play;Positioning Attribute;Protocols documentation;Protons;Regional Anatomy;Research;Research Design;Research Personnel;Residual state;Resistance;Resolution;Role;Schizophrenia;Signal Transduction;simulation;Slice;spectroscopic imaging;Stroke;stroke patient;structural imaging;suburb;Techniques;Technology;Testing;Time;Tissues;tool;United States National Institutes of Health;Variant;Water

PROJECT_TITLE: Magnetic Resonance Spectroscopy Core Facility


PI_NAMEs: LEOPOLD, DAVID A (contact)

PROJECT_TERMS: Adopted;anatomic imaging;Anatomy;Area;Atlases;awake;basal forebrain;Biological;Blood;Blood flow;Brain;brain electrical activity;Brain imaging;Categories;Clinical;Cognition;Cognitive;cognitive process;cognitive task;combinatorial;Communities;comparative;Complex;Conceptions;Contrast Media;Core Facility;Coupling;Data;Data Analyses;Data Files;data sharing;Data Storage and Retrieval;Dedications;design;Development;Devices;Diffusion;Diffusion Magnetic Resonance Imaging;diffusion weighted;Disease;Electrodes;Electrophysiology (science);Elements;Engineering;Environment;Evaluation;Experimental Designs;experimental study;Fiber;Functional Imaging;Functional Magnetic Resonance Imaging;functional MRI scan;Future;Goals;Haplorhini;Health;Human;Image;imaging facilities;imaging modality;Imaging Techniques;Implant;improved;Individual;Injections;interest;Investigation;Joints;Laboratories;Learning;Magnetic Resonance Imaging;Mammals;Maps;Measures;Medicine;member;Methods;Microelectrodes;Modernization;MRI Scans;multimodality;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;Nature;neural;Neuroanatomy;neurophysiology;Neurosciences;Neurosciences Research;neurotransmission;Noise;operation;Operative Surgical Procedures;Pathway interactions;Pattern;Perception;pharmacologic;Physics;Play;Positioning Attribute;Positron-Emission Tomography;Primates;Procedures;Process;Production;Prosimii;Protocols documentation;Publishing;radio frequency;Regulation;Research;Research Personnel;Research Project Grants;response;Rest;Role;Scanning;Scientist;sensory stimulus;Series;Services;Signal Transduction;Site;skills;Statistical Computing;structural imaging;Structure;Supervision;Technology;Testing;Thinking;Time;tractography;Training;United States National Institutes of Health;Visualization;white matter;Work;X-Ray Computed Tomography

PROJECT_TITLE: Neurophysiology Imaging Facility Core:  Functional and Structural MRI


NIH_SPENDING_CATS: Anxiety Disorders;Basic Behavioral and Social Science;Behavioral and Social Science;Biodefense and Related Countermeasures;Biotechnology;Bipolar Disorder;Brain Disorders;Clinical Research;Coronaviruses;Coronaviruses Disparities and At-Risk Populations;Depression;Emerging Infectious Diseases;Genetics;Human Genome;Infectious Diseases;Mental Health;Mental Illness;Neurosciences;Schizophrenia;Serious Mental Illness;Women's Health Research

PI_NAMEs: MARENCO, STEFANO  (contact)

PROJECT_TERMS: 17q21;Acetylation;Age;age acceleration;aging mechanism;Alternative Splicing;Alzheimer's Disease;Amygdaloid structure;Anatomy;Anterior;Anxiety Disorders;Applications Grants;Archives;Atlases;Attention Deficit Disorder;Attention deficit hyperactivity disorder;Audiotape;Authorization documentation;autism spectrum disorder;Autopsy;Behavior;Bioinformatics;biological sex;Bipolar Disorder;Blood - brain barrier anatomy;Blood specimen;Brain;brain dysfunction;Brain region;brain tissue;Cadaver;cDNA Library;Cell Nucleus;Cells;Cessation of life;ChIP-seq;Chromosomes;chronic pain;chronic painful condition;Chronic stress;cingulate cortex;Classification;Clinical;Code;Collection;Communities;Consent;COVID-19;Craniocerebral Trauma;Data;Data Set;database of Genotypes and Phenotypes;Databases;Depressive disorder;Development;Diagnosis;Diagnostic;Disease;DNA;DNA Methylation;DNA sequencing;Dorsal;Down's Syndrome;Dura Mater;Electronic Mail;entorhinal cortex;Equipment and supply inventories;Equity;Evaluation;Exposure to;Extramural Activities;Family;Fibroblasts;Formalin;Freezing;Frozen Sections;Functional disorder;Genetic;Genetic study;genome sequencing;genomic data;Genomics;Genotype;Goals;Hair;Haplotypes;health data;healthy aging;Hippocampus;Histologic;Histology;Human;human data;Human Genome;Human Resources;Immunization;Immunologics;improved;Individual;Inhibitory Synapse;insight;Institution;Insula of Reil;International Classification of Diseases;Interview;Intramural Research Program;Label;Letters;Link;Long COVID;Major Depressive Disorder;Major Mental Illness;Medical;Medical Examiners;Medical Records;Menopausal Status;Mental Depression;Mental disorders;Mental Health;metabolome;Metastatic malignant neoplasm to brain;Methylation;Mission;Mitochondria;Molecular;multiple omics;Mutation;National Institute of Mental Health;Nerve Degeneration;Nervous System Disorder;Neuroanatomy;Neurons;neuropathology;new technology;novel therapeutics;Obsessive-Compulsive Disorder;Ovary;Parkinsonian Disorders;Patients;Population;Post-Traumatic Stress Disorders;Prefrontal Cortex;Preparation;Prevention strategy;Process;Progressive Multifocal Leukoencephalopathy;Proteome;Proteomics;Psychiatric Diagnosis;Psychotic Disorders;public database;putamen;Recording of previous events;Reporting;reproductive;Research;Research Personnel;Research Support;Resources;Risk;RNA;Role;sample collection;Sampling;SARS-CoV-2 exposure;SARS-CoV-2 infection;Schizoaffective Disorders;Schizophrenia;Serology test;Services;single cell analysis;single nucleus RNA-sequencing;Slice;Slide;small cell lung carcinoma;social health determinants;somatosensory;Specimen;Structure of choroid plexus;Structure of middle temporal gyrus;Structure of trigeminal ganglion;Substance abuse problem;Substance Use Disorder;subventricular zone;suicidal behavior;Suicide;Superior sagittal sinus;Superior temporal gyrus;Swab;Synapses;Synaptic plasticity;tau Proteins;Technology;Testing;Thalamic structure;Thick;Time;Tissue imaging;Tissue Sample;Tissues;tool;transcriptome;transcriptome sequencing;transcriptomic profiling;transcriptomics;United States National Institutes of Health;Virginia;Virus;web site;whole genome;Woman

PROJECT_TITLE: Procurement and Characterization of Postmortem Brain Tissue


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: DOLD, GEORGE  (contact)

PROJECT_TERMS: 3-Dimensional;3D Print;Acceleration;Affect;Animals;Area;Assessment tool;Association Learning;Attention;Auditory;Behavior;behavior test;Behavioral;behavioral study;Brain;Clinical;Cognitive;Collaborations;Complex;Computer software;Consult;Core Facility;Cues;Custom;data acquisition;Data Analyses;Data Collection;Decision Making;Dedications;design;design and construction;Development;Devices;Drosophila genus;Effectiveness;electric field;Electroconvulsive Therapy;Electrodes;Electroencephalography;Electronic Mail;Electronics;Electrophysiology (science);Engineering;Ensure;Environment;Equipment;experience;experimental study;fabrication;Fiber Optics;Food;Functional disorder;Functional Magnetic Resonance Imaging;Goals;graphical user interface;Head;Hour;Human;Image;improved;Individual;Industrialization;Insecta;insight;instrument;instrumentation;Investigational Therapies;Learning;Light;locust;Magnetic Resonance Imaging;manufacture;Mechanics;Memory;Metals;Microscope;Mission;Monkeys;Motivation;Motor;Mus;National Center for Complementary and Integrative Health;National Institute of Child Health and Human Development;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;neuromechanism;new technology;Noise;novel;Occupations;Optics;Output;Pattern;Perfusion;Positioning Attribute;Primates;Process;product development;Production;Productivity;prototype;Radiochemistry;Recommendation;Research;Research Personnel;Research Project Grants;Research Support;Resolution;response;Reverse engineering;Rewards;Rodent;Running;Scientist;sensor;Shelter facility;Side;side effect;software development;Speed;Stimulus;Structure;System;Techniques;Technology;Telephone;Testing;Time;Titanium;tool;treatment-resistant depression;two photon microscopy;United States National Institutes of Health;user friendly software;Visual Perception;voltage;Walking

PROJECT_TITLE: NIMH Instrumentation Core Facility


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Machine Learning and Artificial Intelligence;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: CHUDASAMA, YOGITA  (contact)

PROJECT_TERMS: 3-Dimensional;Address;Animal Behavior;Animals;Attention;Behavior;Behavior Disorders;behavior test;Behavioral;Behavioral Model;Behavioral Research;behavioral response;behavioral study;Biological Psychiatry;Body part;Brain;Brain Diseases;Calcium;Calcium Signaling;Calibration;Code;Cognition;Cognitive;Cognitive deficits;cognitive function;Collaborations;Complex;computer code;Computer software;Computer Vision Systems;Controlled Environment;Core Facility;Cues;Custom;Darkness;Data;data analysis pipeline;Data Set;Decision Making;deep learning;deep learning model;Deposition;Depth Perception;design;Destinations;Development;Discrimination;Ecology;Education;Emerging Technologies;Emotional;emotional behavior;Emotions;Ensure;Environment;Equipment;Ethology;experimental study;Fiber;flexibility;Fluorescence;Fostering;Goals;Health;Human;Image;Implant;improved;indexing;Individual;Infrastructure;innovation;Interdisciplinary Study;Investigation;Journals;large datasets;Learning;Lighting;Link;Location;Logic;Machine Learning;Maintenance;Measures;Memory;Methods;millisecond;miniaturize;Molecular;Motor;Motor Activity;motor behavior;Movement;Mus;National Heart, Lung, and Blood Institute;National Human Genome Research Institute;National Institute of Allergy and Infectious Disease;National Institute of Biomedical Imaging and Bioengineering;National Institute of Child Health and Human Development;National Institute of Diabetes and Digestive and Kidney Diseases;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;National Institute on Deafness and Other Communication Disorders;Nature;neural;Neuroanatomy;neurochemistry;Neurodegenerative Disorders;Neurodevelopmental Disorder;Neurons;neuropsychiatric disorder;Neurosciences;Nose;open source;optogenetics;Output;Pathology;Pattern;Peer Review;Photometry;Physiological;Principal Investigator;Printing;Problem Solving;Psychiatry;Publishing;Rattus;Reaction;Reproducibility;Research;research facility;Research Personnel;Resources;response;Rodent;Rodent Model;Science;Scientist;Sensory;Series;Short-Term Memory;Sorting;Speed;Standardization;statistics;stereoscopic;System;Techniques;Testing;Time;touchscreen;Transistors;translational medicine;translational neuroscience;Translational Research;United States National Institutes of Health;usability;Validity and Reliability;virtual;Visual;Wisconsin;Writing

PROJECT_TITLE: Rodent Behavioral Core: The Analysis of Behavior


NIH_SPENDING_CATS: Biomedical Imaging;Clinical Research;Data Science;Machine Learning and Artificial Intelligence;Mental Health;Neurosciences

PI_NAMEs: THOMAS, ADAM G (contact)

PROJECT_TERMS: Acceleration;Adolescent;Affective Symptoms;Age;Aging;biobank;Books;Brain;Brain imaging;Brain Mapping;Child;Clinical;Clinical assessments;Clinical Data;Code;Cognition;cognitive development;Collaborations;Communication;Communities;Complex;connectome;Data;data curation;data dissemination;data management;data repository;Data Science;Data Set;data sharing;data standards;Data Storage and Retrieval;data submission;Deposition;design;Development;Ecological momentary assessment;efficacy evaluation;Ensure;Evaluation;falls;Foundations;Functional Magnetic Resonance Imaging;Genetic;Genome;Genomics;Goals;Guidelines;Human;improved;innovation;insight;Intramural Research Program;Lead;Link;Machine Learning;machine learning method;Magnetic Resonance Imaging;meetings;member;Mentors;Methods;Mind;MRI Scans;National Institute of Mental Health;Nature;Neurocognitive;neurogenomics;neuroimaging;Neurologic;Neurons;Neurosciences;open data;Paper;Participant;Phenotype;phenotypic data;Policies;Positioning Attribute;posters;Printing;programs;Protocols documentation;public repository;Publications;Publishing;Reproducibility;Research;Research Personnel;residence;Residencies;Sampling;Scanning;Science;Scientist;Seasons;Sex Differences;simulation;South Korea;Standardization;Structure;symposium;Time;tool;Training;training data;United States National Institutes of Health;Universities;Update;volunteer;web site;Work;working group

PROJECT_TITLE: Data Science and Sharing Team


NIH_SPENDING_CATS: Autism;Behavioral and Social Science;Biotechnology;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Disability Research;Genetics;Intellectual and Developmental Disabilities (IDD);Mental Health;Neurosciences;Pediatric

PI_NAMEs: THURM, AUDREY  (contact)

PROJECT_TERMS: active duty;Adaptive Behaviors;Address;Area;autism spectrum disorder;Behavior;Behavior assessment;behavioral phenotyping;Biological Markers;brain based;Characteristics;Child;Child of Impaired Parents;Childhood;Clinical;Clinical Research;clinical trial readiness;Clinical Trials;Cognitive;cognitive function;Collaborations;Communication;Consultations;Creatine;Data;Data Analyses;Data Collection;data exploration;Detection;Development;Developmental Delay Disorders;Developmental Disabilities;Diagnosis;Diagnostic;Discipline;Disease;drug development;Drug Evaluation;Electrophysiology (science);Enrollment;epidemiology study;Evaluation;experience;Extramural Activities;Family;Functional impairment;Gangliosidoses;gene therapy;Genetic Diseases;Genotype;Goals;Grain;Human;Impairment;improved;Individual;innovation;Intellectual functioning disability;interest;Intervention Studies;Intramural Research Program;Investigation;ketotic hyperglycinemia;Light;longitudinal course;Measurement;Measures;Medical;meetings;Mental disorders;Metabolic Diseases;Mission;Modality;Molecular Abnormality;multidisciplinary;National Institute of Mental Health;Natural History;Nature;neurodevelopment;Neurodevelopmental Disability;Neurodevelopmental Disorder;neuroimaging;novel;novel therapeutics;Ontology;Outcome;Outcome Measure;participant enrollment;Patients;Performance;Persons;Phenotype;Population;Population Study;predictive marker;Process;programs;Property;protocol development;Protocols documentation;Psyche structure;psychologic;Psychometrics;Rare Diseases;repository;Research;Research Personnel;research study;Resources;Risk;Sampling;Services;skill acquisition;skills;social;Social Functioning;standardize measure;Symptoms;Syndrome;System;Tablets;Terminology;Testing;Therapeutic Agents;therapeutic gene;Time;tool;Translational Research;Treatment outcome;treatment trial;United States National Institutes of Health;Update;Validation;Work

PROJECT_TITLE: Neurodevelopmental and Behavioral Phenotyping


NIH_SPENDING_CATS: Bioengineering;Genetics;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: USDIN, THEODORE  (contact)

PROJECT_TERMS: 3-Dimensional;Algorithms;analysis pipeline;Anatomy;Antibodies;Area;Atlases;Brain;Brain imaging;Brain Mapping;Brain region;calcium indicator;Callithrix;Callithrix jacchus jacchus;Carbon Dioxide;cell type;Cells;Code;Collaborations;Computer software;confocal imaging;Confocal Microscopy;Corpus striatum structure;COVID-19 pandemic;cryostat;Custom;Data;Data Set;denoising;design;detector;Development;Dimensions;Dopamine Receptor;Dorsal;Dynorphins;Equilibrium;Equipment;Female;Gene Activation;Gene Expression;Gene Expression Profile;Genetic;Histologic;Image;Image Analysis;image processing;Immediate-Early Genes;In Situ Hybridization;Individual;innovation;insight;instrument;interest;Intramural Research Program;Investigation;kappa opioid receptors;Label;Laboratories;Laser Scanning Confocal Microscopy;Lasers;Light;light microscopy;Lighting;Macaca;Machine Learning;Maintenance;male;Messenger RNA;Methods;Microscope;microscopic imaging;Microscopy;Microtome - medical device;Mission;Molecular;Morphology;Motivation;multi-photon;Mus;National Institute of Mental Health;Nature;Neurons;Neurosciences;Nucleic Acid Probes;operation;Opsin;Optics;Ovariectomy;Pathway interactions;Pattern;Performance;Physiologic pulse;Pilot Projects;Population;Prefrontal Cortex;Preparation;presynaptic;Procedures;programs;protein distribution;Proteins;Psychiatry;Psychological reinforcement;Publications;Pythons;raphe nuclei;reconstruction;Recurrence;Regulation;Research Personnel;Research Project Grants;Resolution;Resources;routine imaging;Sampling;Scanning;Shapes;Slide;social;Specific qualifier value;Stimulus;student training;System;Techniques;Technology;Thick;Time;Tissue imaging;tissue preparation;Tissues;tool;Training;transmission process;United States National Institutes of Health;Vendor;Visualization;Work

PROJECT_TITLE: Systems Neuroscience Imaging Resource


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Brain Disorders;Data Science;Depression;Machine Learning and Artificial Intelligence;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences;Pediatric

PI_NAMEs: PEREIRA, FRANCISCO  (contact)

PROJECT_TERMS: Accounting;Address;Adolescent;Affective;Atlases;Bayesian Analysis;Behavior;Behavioral;Brain;Brain Mapping;Characteristics;child depression;Clinical;Code;Cognitive;Communities;Computer software;Confounding Factors (Epidemiology);Consultations;Consumption;COVID-19;COVID-19 pandemic;Data;Data Science;Data Set;data sharing;Databases;deep neural network;design;Development;dimension reduction;Dimensions;Distress;Drops;dynamic system;Ecological momentary assessment;Event;experience;Experimental Designs;experimental study;Extinction;Face;Family dynamics;Fiber;Functional Magnetic Resonance Imaging;Goals;Guidelines;high risk;Hour;Human;Image;improved;Individual;individual variation;interest;Intramural Research Program;Judgment;large language model;large-scale imaging data;Location;Loneliness;Machine Learning;machine learning method;Maps;Measurement;Measures;Medial;Mental Depression;mental representation;Methodology;Methods;Mission;Moods;Motivation;National Institute of Drug Abuse;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;National Institute on Alcohol Abuse and Alcoholism;neural;Neurons;Neurosciences;optogenetics;Outcome;pandemic disease;Participant;Performance;Persons;Phenotype;Photometry;Postbaccalaureate;Postdoctoral Fellow;Prefrontal Cortex;Preparation;presynaptic;Principal Investigator;Printing;Procedures;Process;Psychiatry;Psychology;Psychopathology;Publishing;Quality Control;Quantitative Evaluations;Questionnaires;randomized trial;Reading;Research;Research Activity;Research Personnel;Rest;Retrieval;Rewards;Services;Shapes;Signal Transduction;Social Distance;Space Models;Statistical Methods;statistics;Structural Models;Structure;Students;Surveys;Testing;Text;Thinking;Time;tool;Training;Transcranial magnetic stimulation;United States National Institutes of Health;usability;Validation;Well in self;Youth

PROJECT_TITLE: Machine Learning Team


NIH_SPENDING_CATS: Biotechnology;Cardiovascular;Genetics;Mental Health;Neurodegenerative;Neurosciences;Pediatric;Rare Diseases;Regenerative Medicine;Spinal Muscular Atrophy;Stem Cell Research;Stem Cell Research - Embryonic - Human;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

PI_NAMEs: ROBEY, PAMELA  (contact)

PROJECT_TERMS: 3-Dimensional;Adenine;Aging;Animal Model;Antisense Oligonucleotide Therapy;Area;Atrophic;autosome;Bacteria;biological adaptation to stress;Cardiac;Cardiac Myocytes;cell community;Cell Culture Techniques;Cell Cycle;Cell Death;Cell Differentiation process;Cell Line;Cell Nucleus;cell type;Cells;Cessation of life;Chromosomal Stability;Clustered Regularly Interspaced Short Palindromic Repeats;Collaborations;comparative;CRISPR/Cas technology;Cytoplasm;Data;Deacetylase;Derivation procedure;Development;differentiation protocol;Dinucleoside Phosphates;Disease;disease model;DNA Repair;DNA Sequence Alteration;Down's Syndrome;drug discovery;Educational process of instructing;Endocrine;Exhibits;Fibroblasts;Formulation;gene editing technology;gene repression;Generations;Genes;Genetic Engineering;Genetic Recombination;Genome;Genome Stability;Genomics;Goals;Hormone replacement therapy;Hormones;Human;human embryonic stem cell;human induced pluripotent stem cells;human pluripotent stem cell;Hydrolase;Hydrolysis;Hypophysectomy;Hypopituitarism;Hypoxia;Immune;Immunofluorescence Immunologic;Immunomodulators;implantation;induced pluripotent stem cell;induced pluripotent stem cell technology;Informal Social Control;Inherited;insight;interest;Knock-out;Maintenance;Mammals;Manuscripts;member;Mentors;Meta-Analysis;Metabolic;metabolome;Methods;Microglia;Microtubules;Mission;Mitochondria;Monitor;Mosses;Motor Neurons;Mus;Muscle;mutant;Mutation;mutation correction;National Heart, Lung, and Blood Institute;National Human Genome Research Institute;National Institute of Environmental Health Sciences;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;nerve stem cell;Neuromuscular Diseases;Neurons;neuropsychiatry;Neurosphere;Nicotine;novel;Organ;Organism;Organoids;Oxidative Stress;Patients;Pattern;Peripheral Blood Mononuclear Cell;Pituitary Gland;Pituitary Gland Adenoma;Pituitary-dependent Cushing's disease;Play;pluripotency;pluripotent stem cell differentiation;Pluripotent Stem Cells;Poly Adenosine Diphosphate Ribose;pre-clinical;Preclinical Drug Development;Preparation;Process;Property;Proteins;Protocols documentation;Publishing;PubMed;Quality Control;Reporter;Research;Research Project Grants;Respiratory distress;response;Role;Sampling;Scientist;self-renewal;Sendai virus;Side;SIRT1 gene;Sirtuins;Societies;Spinal Cord;Spinal Muscular Atrophy;Spinal Muscular Atrophy with Respiratory Distress Type I;stem cell biology;stem cell biomarkers;stem cell growth;stem cell survival;stem cells;stress management;System;TP53 gene;Training;United States National Institutes of Health;Variant;Work

PROJECT_TITLE: Human pluripotent stem cells


NIH_SPENDING_CATS: Biomedical Imaging;Brain Disorders;Cerebrovascular;Clinical Research;Health Services;Neurosciences;Stroke

PI_NAMEs: LATOUR, LAWRENCE  (contact)

PROJECT_TERMS: Accident and Emergency department;Accreditation;acute stroke;Blood Vessels;Cerebrum;Clinical;clinical center;Clinical Research;clinical research site;Clinical Services;computer network;Contractor;Data;Elements;Event;Fellowship;Foundations;Hospitals;Image;Infrastructure;Injury;Location;Magnetic Resonance Imaging;Maryland;Neurologist;Neurology;Nurses;participant enrollment;Patients;programs;Protocols documentation;recruit;Registries;Research;Research Infrastructure;Research Project Grants;Research Subjects;Research Support;screening;Services;Site;Source;Stroke;suburb;System;Training;Training Programs;Traumatic Brain Injury;United States National Institutes of Health;Washington

PROJECT_TITLE: Clinical And Imaging Core Support Of Acute Stroke Research


NIH_SPENDING_CATS: Neurosciences

PI_NAMEs: DEVINE, RITA  (contact)

PROJECT_TERMS: Animals;Area;Biophysics;Cellular biology;Clinical;Core Facility;cost effective;Environment;Epilepsy;Equipment;Evaluation;Excision;Friends;Genetic;Goals;improved;Infrastructure;Laboratories;Lighting;Location;Magnetic Resonance Imaging;Maintenance;Minor;Modification;National Institute of Neurological Disorders and Stroke;Neurology;Neurosciences;Operative Surgical Procedures;Phase;programs;Research;Research Support;Resources;Scientist;Stroke;System;United States National Institutes of Health;Water

PROJECT_TITLE: Maintenance and Improvement of NINDS Infrastructure


NIH_SPENDING_CATS: Biotechnology;Brain Cancer;Brain Disorders;Cancer;Infectious Diseases;Neurosciences;Orphan Drug;Rare Diseases;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

PI_NAMEs: NATH, AVINDRA  (contact)

PROJECT_TERMS: Alzheimer's Disease;antagonist;Antibodies;Astrocytes;Attenuated;Binding;Biological Assay;Biological Products;Bipolar Disorder;Caenorhabditis elegans;Cell Culture Techniques;Cell Line;Cells;chemosensitizing agent;Chronic;Collaborations;Collection;Development;dopamine D3 receptor;Endogenous Retroviruses;env Gene Products;Epilepsy;Extramural Activities;Fluorescence;Fluorescence Microscopy;FRAP1 gene;Generations;Glioblastoma;Glioma;Goals;HIF1A gene;high throughput screening;HIV;HIV tat Protein;Human;Image;imaging platform;In Vitro;in vivo;induced pluripotent stem cell;Induced pluripotent stem cell derived neurons;inhibitor;Interferometry;Label;Laboratories;Lead;live cell imaging;Mediating;Modeling;Mutation;National Center for Advancing Translational Sciences;National Institute of Allergy and Infectious Disease;National Institute of Neurological Disorders and Stroke;neoplastic cell;Nerve Degeneration;Nerve Regeneration;nerve stem cell;Nervous System Disorder;nervous system infection;Neurons;neuroprotection;neurotoxic;neurotoxicity;North Dakota;novel therapeutics;Patients;Pituitary-dependent Cushing's disease;Population;Potassium;preclinical development;programs;Progress Reports;promoter;Property;protein purification;Proteins;Recombinant Proteins;Recombinants;Research Personnel;Research Project Grants;Role;Sampling;Schools;Scientist;screening;small molecule;small molecule libraries;stem cell niche;stemness;tat Protein;Therapeutic Agents;therapeutic target;Translational Research;Virus Replication;Work

PROJECT_TITLE: Progress Report for Neurotherapeutics Unit


PI_NAMEs: KORETSKY, ALAN  (contact)

PROJECT_TERMS: Address;Amplifiers;animal imaging;Animals;arterial spin labeling;Autopsy;Bite;Boston;Brain;Brain imaging;Callithrix;Cell Nucleus;Cells;Computer software;Coupled;Coupling;Data Reporting;Dedications;design;Detection;Development;Devices;Diameter;electric impedance;Electromagnetic Fields;Electronics;Elements;Engineering;experimental study;Frequencies;Functional Imaging;Functional Magnetic Resonance Imaging;Future;Generations;Goals;Head;Heating;Human;human imaging;human subject;Image;improved;in vivo;Infrastructure;Institutional Review Boards;instrumentation;interest;Intervention;Iron;Isopropanol;Label;Laboratories;magnetic field;Magnetic Resonance Imaging;Maps;Measurement;Measures;Mechanics;medical specialties;Methods;Modeling;molecular imaging;Monitor;nanofabrication;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;neuroimaging;Neurosciences;new technology;next generation;Noise;novel;Nuclear;nuclear imaging;operation;Operative Surgical Procedures;Optics;particle;Performance;Perfusion;perfusion imaging;Pituitary Gland;Polychlorinated Biphenyls;Povidone;Principal Investigator;Property;Protocols documentation;radio frequency;radiologist;Ramp;Recipe;Research;Resolution;response;Rhodium;Safety;safety assessment;safety testing;Schedule;Scheme;Sepharose;Shapes;Side;simulation;Source;success;System;Technology;Temperature;Testing;Thermometry;Time;Tissues;Transistors;transmission process;tumor;United States National Institutes of Health;Universities;Validation;Work

PROJECT_TITLE: MRI Engineering Core


NIH_SPENDING_CATS: Autoimmune Disease;Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Coronaviruses;Emerging Infectious Diseases;Infectious Diseases;Machine Learning and Artificial Intelligence;Multiple Sclerosis;Neurodegenerative;Neurosciences

PI_NAMEs: NAIR, GOVIND  (contact)

PROJECT_TERMS: 3D Print;Age;Animals;Area;Arterial Disorder;Atrophic;Autopsy;autosome;Brain;brain based;Brain region;brain tissue;brain volume;Categories;Cells;Cerebrum;Classification;Clinical;clinical center;Clinical Trials;Collaborations;Communities;Computer software;contrast enhanced;Contrast Media;Core Facility;Data Analyses;design;Digital Imaging and Communications in Medicine;falls;Freezing;Goals;graduate student;gray matter;Hematopoietic Stem Cell Transplantation;high resolution imaging;Histopathology;HIV;HIV Seropositivity;Human;Human Resources;Image;imaging facilities;imaging modality;Imaging Techniques;improved;In Situ;in vivo;in vivo imaging;interest;Label;Lesion;Long-Term Effects;Machine Learning;Magnetic Resonance;Magnetic Resonance Imaging;magnetic resonance imaging biomarker;Measures;medication safety;Metastatic malignant neoplasm to brain;Methods;Microscopy;Mission;MRI Scans;Multiple Sclerosis;multiple sclerosis patient;Mus;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;Nervous System Disorder;neuroimaging;Neurologic;Neurology;Neuropsychology;Organ;Outcome Measure;Participant;Pathologic;Pathologic Processes;pembrolizumab;Persons;Phase;Phenotype;Physiologic pulse;Post Technic;Post-Acute Sequelae of SARS-CoV-2 Infection;Postbaccalaureate;Postdoctoral Fellow;Postoperative Period;preservation;Progressive Multifocal Leukoencephalopathy;Research;Research Activity;Research Personnel;Resolution;Resources;RNA;Sampling;SARS-CoV-2 infection;Scanning;segmentation algorithm;Services;Slice;small cell lung carcinoma;socioeconomics;Software Engineering;Spinal Cord;spinal cord imaging;Stroke;Study Subject;Subcortical Infarctions;Subcortical Leukoencephalopathy;Techniques;Testing;Time;Tissue imaging;Tissues;tool;transfer learning;Treatment outcome;ultra high resolution;United States National Institutes of Health;Universities;user-friendly;Visualization;White Matter Hyperintensity;Work

PROJECT_TITLE: NINDS Quantitative MRI Core Facility


PI_NAMEs: SMITH, CAROLYN  (contact)

PROJECT_TERMS: 3-Dimensional;alpha synuclein;Amacrine Cells;Astrocytes;Autophagocytosis;Behavioral;beta-arrestin;Biological;biological adaptation to stress;Biological Markers;Biological Psychiatry;Brain;Breathing;Callithrix jacchus jacchus;Canada;Carbon Dioxide;Cardiac;Carotid Body;CDK5 gene;Cell Nucleus;Cells;Clathrin;Collaborations;Computer software;confocal imaging;constriction;Consultations;Core Facility;Dendritic Spines;Deposition;design;Developmental Stuttering;Diamond;Dopamine D2 Receptor;dopaminergic neuron;Drosophila genus;Endocrine;entorhinal cortex;Epilepsy;Equipment;fatty acid-binding proteins;fear memory;Fiber;G protein coupled receptor kinase;Goals;granule cell;Guanine Nucleotide Exchange Factors;Hares;Image;Image Analysis;image processing;imaging facilities;Immediate-Early Genes;Immune signaling;In Vitro;Individual;instrument;Internet;Journals;Knowledge;Label;Laboratories;Lasers;Learning;Lewy Bodies;Life;Light;Light Microscope;light microscopy;Lipids;Maps;Measures;Medial;Mediating;member;Membrane;Microscope;Microscopic;Mission;Morphology;mouse model;N-Methyl-D-Aspartate Receptors;National Institute of Neurological Disorders and Stroke;Nervous System;Nervous System Disorder;Neurobiology;neurogenic orthostatic hypotension;Neuroglia;Neurons;Neurosciences;noradrenergic;Olfactory dysfunction;open data;Optics;Organism;Patients;Persons;Phosphorylation;Piezo 2 ion channel;pituitary adenylate cyclase activating polypeptide;preBotzinger complex;Property;protein TDP-43;Publications;RAPGEF2 gene;raphe nuclei;receptive field;receptor;reconstruction;recruit;Regulation;Reporting;Research;Resolution;Resources;Sampling;Scanning;Science;Scientist;Secretory Vesicles;Sensory;Sex Functioning;Shapes;Signal Pathway;Slice;Sodium;spatial memory;Structure;Substantia nigra structure;success;Synapses;Techniques;Thick;Thinness;time interval;Training;Transgenic Mice;Ubiquitin;Universities;Variant;Ventral Tegmental Area;Visualization;Work;Yin

PROJECT_TITLE: Light Imaging Core Facility


NIH_SPENDING_CATS: Biotechnology;Genetics;Neurosciences

PI_NAMEs: MARIC, DRAGAN  (contact)

PROJECT_TERMS: Apoptotic;Basic Science;Basophils;Biological;Biological Assay;Biological Markers;Bone Marrow;Calcium;Calibration;Cell Culture Techniques;Cell Death;Cell Differentiation process;Cell membrane;Cell Nucleus;cell preparation;Cell Proliferation;Cell Separation;Cell surface;cell type;Cells;Cellular Assay;Cellular biology;Cerebrospinal Fluid;Clinical Research;Color;Complex;Core Facility;Cytometry;Cytoplasm;cytotoxic;Data;data acquisition;Data Analyses;design;Detection;Dyes;Eligibility Determination;Endothelial Cells;eosinophil;Equipment;Exclusion;experimental study;Flow Cytometry;Fluorescence-Activated Cell Sorting;Gene Expression;Genes;Genetic Markers;Hematopoietic;high throughput screening;Human Resources;Image;Image Cytometry;Imaging Techniques;Immunoprecipitation;In Situ;In Vitro;in vivo;Individual;insight;instrument;interest;investigator training;Journals;Laboratories;Leukocytes;Link;Logic;loss of function;Lymphocyte;Maintenance;Manuscripts;mast cell;Mesenchymal;Microglia;MicroRNAs;Mission;Mitochondria;Molecular;monocyte;multidisciplinary;National Institute of Neurological Disorders and Stroke;Necrosis;neural;Neuroglia;Neurons;neutrophil;novel;Nuclear;Peer Review;peripheral blood;Phenotype;Physiological;Population;Preparation;Productivity;programs;Property;protein expression;Proteins;Protocols documentation;Publications;Quality Control;Reporter;Research;research and development;Research Personnel;Research Project Grants;Research Support;Resources;Reverse Transcriptase Polymerase Chain Reaction;RNA;Sampling;Services;Side;Signal Transduction;Small Interfering RNA;Sorting;Source;specific biomarkers;Specific qualifier value;Spleen;Stains;Standardization;stem;stem cells;Students;Synaptosomes;Technology;Testing;Tissues;Training;transcriptome sequencing;Transfection;Translational Research;Transplantation;United States National Institutes of Health;Western Blotting;Work

PROJECT_TITLE: Flow & Imaging Cytometry Core Facility


PI_NAMEs: LI, YAN  (contact)

PROJECT_TERMS: 2019-nCoV;Acetylation;alpha Tubulin;Anxiety;CDK5 gene;Core Facility;Devices;Disulfide Linkage;Goals;Growth;Hares;High Pressure Liquid Chromatography;Homeostasis;instrument;Intramural Research;Label;Life;LRRK2 gene;Mammalian Cell;mass spectrometer;Mass Spectrum Analysis;Measurement;Membrane;Methods;Mitochondrial Myopathies;Modification;Molecular Weight;Motor;nano;National Institute of Neurological Disorders and Stroke;operation;Paper;Phosphorylation;Post-Translational Protein Processing;Printing;protein TDP-43;Proteins;Proteomics;Regulation;Research Personnel;Research Support;Scientist;Services;Signal Pathway;Sorting;Stress;Synapses;System;Techniques;Training;Translational Protein Modification;Translations;Ubiquitination;United States National Institutes of Health;Work

PROJECT_TITLE: Proteomics Core Facility


NIH_SPENDING_CATS: Bioengineering;Biotechnology;Clinical Research;Genetics;Human Genome;Networking and Information Technology R&D (NITRD);Neurosciences;Stem Cell Research;Stem Cell Research - Embryonic - Human;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

PI_NAMEs: JOHNSON, KORY  (contact)

PROJECT_TERMS: American Heart Association;Animals;Appropriateness Review;Area;ATAC-seq;Awareness;B-cell receptor repertoire sequencing;Bioinformatics;cell registry;ChIP-seq;Classification;Clinical;Clinical Data;Collection;Communication;Companions;Core Facility;Data;Data Analyses;Databases;design;Development;DNA methylation profiling;Endogenous Retroviruses;Equipment and supply inventories;expectation;experience;Generations;Genes;Guidelines;Health Professional;Hospitalization;Hospitals;human embryonic stem cell;human pluripotent stem cell;Image;Integral Membrane Protein;Journals;Lesion;Machine Learning;Maintenance;Manuscripts;Mass Spectrum Analysis;meetings;Messenger RNA;Methods;Microarray Analysis;MicroRNAs;middleware;mobile application;Modeling;molecular dynamics;Names;National Institute of Neurological Disorders and Stroke;next generation;Online Systems;pathogen;Patients;Phylogenetic Analysis;Process;Protein Analysis;Protein Microarray Assay;Proteins;recruit;Research;Research Personnel;RNA analysis;Schedule;Secure;Sequence Analysis;Severities;single-cell RNA sequencing;Site;Statistical Data Interpretation;stroke patient;Structure;Survival Analysis;symposium;System;T cell receptor repertoire sequencing;Technology;Testing;Time;tool;transcriptome sequencing;transcriptomics;United States National Institutes of Health;Variant;web app;Work

PROJECT_TITLE: Bioinformatics Core Facility


NIH_SPENDING_CATS: Brain Cancer;Brain Disorders;Cancer;Neurosciences;Rare Diseases

PI_NAMEs: TAO-CHENG, JUNG-HWA  (contact)

PROJECT_TERMS: Adult;age related;Biological Sciences;blood-brain tumor barrier;Brain;Cells;Clathrin;constriction;Consultations;Core Facility;Data;Electron Microscope;Electron Microscopy;experience;Fostering;Glioma;Goals;Growth;high resolution imaging;Hippocampus;Homeostasis;Image;Image Analysis;improved;Inhibitory Synapse;Iron;journal article;Label;Magnetic Resonance Imaging;Mediating;meetings;member;Membrane;Microscope;Microtomy;Mitochondrial Myopathies;Modeling;Molecular;Mus;National Institute of Neurological Disorders and Stroke;Neuroglia;Neurosciences;olfactory bulb;Paper;Preparation;Printing;Proteins;Publications;Research Personnel;Rest;Rodent;sample fixation;Sampling;Scientist;Stem cell transplant;Techniques;tissue preparation;tissue processing;Training;Translations;transmission process;Work;young adult

PROJECT_TITLE: Electron Microscopy Core Facility


NIH_SPENDING_CATS: Amyotrophic Lateral Sclerosis (ALS);Biodefense and Related Countermeasures;Biotechnology;Brain Disorders;Emerging Infectious Diseases;Genetics;Infectious Diseases;Neurodegenerative;Neurosciences;Rare Diseases;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human;Vector-Borne Diseases

PI_NAMEs: WANG, DAVID  (contact)

PROJECT_TERMS: 2019-nCoV;3-Dimensional;Adopted;Adult;Affect;Antibodies;Antisense Oligonucleotides;Artificial Intelligence;Astrocytes;Axon;Biological Assay;Blood - brain barrier anatomy;blood-brain barrier disruption;Brain;brain research;C9ORF72;CD34 gene;Cell Line;cell type;Cells;Coculture Techniques;Collaborations;Communicable Diseases;Communities;Congresses;Dengue Infection;Dengue Virus;design;Development;Diagnosis;diagnostic development;Disease;DNA;DNA Repair;Educational workshop;Embryoid bodies;Endogenous Retroviruses;Endothelial Cells;Epigenetic Process;Extramural Activities;Extravasation;gene correction;Genetic;Genetic study;Glial Differentiation;Goals;hematopoietic stem cell differentiation;Hematopoietic stem cells;Human;image processing;In Vitro;India;induced pluripotent stem cell;Inflammation;Inflammatory;interest;International;Journals;Label;Methods;Microfluidic Microchips;Microglia;Mitochondria;Modeling;Molecular Target;Monitor;Morphology;motor neuron degeneration;Motor Neurons;Mutation;National Institute of Neurological Disorders and Stroke;Nerve Degeneration;nerve stem cell;Nervous System Disorder;neural;neural model;neurodevelopment;Neurodevelopmental Disorder;neurogenesis;neuroimmunology;neuroinflammation;Neurology;Neurons;Neurosciences;neurotoxicity;Normalcy;novel;Organoids;Pathogenesis;Pathway interactions;patient derived induced pluripotent stem cells;Patients;Penetration;Peripheral;Phosphorylation;Play;pluripotent stem cell differentiation;Postdoctoral Fellow;preclinical study;preservation;prevent;Process;Production;Property;protein TDP-43;Proteins;Protocols documentation;Publications;Publishing;Recombinants;reconstitution;research and development;Research Personnel;response;Retroviridae;Role;Sampling;SARS-CoV-2 spike protein;screening;Serum;single-cell RNA sequencing;Site;Small Interfering RNA;Spain;Standardization;Stem Cell Research;stem cells;Stimulator of Interferon Genes;Testing;Tetradecanoylphorbol Acetate;therapeutic development;Therapeutic Intervention;three-dimensional modeling;Toxic effect;trafficking;Training;translational neuroscience;United States National Institutes of Health;Virus;Virus Activation;Virus Diseases;Western Blotting;Work;XRCC5 gene

PROJECT_TITLE: Neurodifferentiation/Stem Cell Unit


NIH_SPENDING_CATS: Biomedical Imaging;Brain Disorders;Clinical Research;Health Disparities Research;Health Disparities and Racial or Ethnic Minority Health Research;Neurosciences;Rare Diseases;Social Determinants of Health

PI_NAMEs: HOROVITZ, SILVINA  (contact)

PROJECT_TERMS: Administrator;brain morphology;Brain Neoplasms;Brain Pathology;Cerebellar Ataxia;Clinic;Clinical;Clinical Research;Clinical Research Protocols;Collection;Communities;community based research;community engaged approach;community engagement;comparative;cost;County;Data;Data Collection;demographics;disabled;Disease Progression;Enrollment;equity, diversity, and inclusion;field study;follow up assessment;follow-up;Fostering;Future;Goals;Grant;health equity;health inequalities;improved;Incidence;Individual;Institutional Review Boards;Magnetic Resonance Imaging;multimodality;National Institute of Neurological Disorders and Stroke;Nervous System Disorder;Neurodegenerative Disorders;Neuroepidemiology;Neurologic;Neurology;operation;Operations Research;Optical Coherence Tomography;outreach;Participant;Patients;Physicians;Pilot Projects;point of care;point of care testing;Population;programs;Protocols documentation;Research;Research Project Grants;screening;social health determinants;Stroke;System;Underserved Population;Vision;Work

PROJECT_TITLE: Mobile Clinical Research


PI_NAMEs: YU, ZANLIN  (contact)

PROJECT_TERMS: Address;Biological;Charge;Chills;Communities;Computer software;Core Facility;Cryoelectron Microscopy;Data Analyses;Data Collection;data management;Data Storage and Retrieval;Diagnosis;Electron Microscope;Electron Microscopy Facility;experience;Freezing;Goals;improved;Microscope;National Institute of Neurological Disorders and Stroke;operation;Preparation;Research Personnel;Resolution;Running;Sampling;screening;structural biology;Structure;Training;Update;Water

PROJECT_TITLE: Cryo-EM Core Facility


NIH_SPENDING_CATS: Clinical Research;Neurosciences

PI_NAMEs: AMIN, NIRANJANA  (contact)

PROJECT_TERMS: Authorization documentation;Back;Biological;Biological Assay;Biological Specimen Banks;Blood specimen;Cataloging;Catalogs;chemokine;Clinical;Clinical Data;Clinical Protocols;Clinical Research;Collection;Color;Computer software;Core Facility;cytokine;Data;Databases;Development;DNA;experience;Flow Cytometry;Future;Genus Hippocampus;Goals;Human Resources;Individual;Institution;interest;Knowledge;Laboratories;Laboratory Research;Light;Link;Long COVID;Maintenance;Measures;meetings;member;Mission;Mitochondria;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;Nervous System Disorder;Nervous System Trauma;neurofilament;participant enrollment;Patients;peripheral blood;Procedures;Process;Proteins;Protocols documentation;Records;Recruitment Activity;repository;Research;Research Personnel;Resources;Running;sample collection;Sampling;Scientist;Services;Shipping;single molecule;skills;Sorting;Source;Specific qualifier value;Specimen;Specimen Handling;System;tau Proteins;Time;United States National Institutes of Health;web site;Workload

PROJECT_TITLE: Biospecimen Repository Core


ACTIVITY: ZID

NIH_SPENDING_CATS: Behavioral and Social Science;Clinical Research;HIV/AIDS;Health Services;Mental Health;Neurosciences;Patient Safety

PI_NAMEs: PAO, MARYLAND  (contact)

PROJECT_TERMS: 2019-nCoV;Accreditation;advanced directive;Advertising;Advocacy;Annual Reports;anti-depressive agents;Authorization documentation;Autoimmune;Basic Science;Behavior;behavioral phenotyping;Bioethics;Brain;Brain Diseases;Budgets;career;Charge;Childhood;Clinical;clinical care;clinical center;Clinical Competence;clinical examination;clinical implementation;clinical practice;Clinical Protocols;Clinical Research;Clinical Services;clinical training;Clinical Trials;Clinical Trials Data Monitoring Committees;Cognitive;cognitive testing;Cognitive Therapy;Collaborations;Communication;Communities;community engagement;Community Outreach;Complex;Consent;Consultations;COVID-19;COVID-19 pandemic;Credentialing;data management;data sharing;design;Development;Devices;Diagnosis;Discipline of Nursing;Education;Ensure;equity, diversity, and inclusion;Ethics;Evaluation;experience;Faculty;Fellowship;flu;follow-up;Future;genome sequencing;Good Clinical Practice;Health Priorities;Health Professional;Health Services Research;high risk;Hospitals;Human Resources;human subject protection;improved;Individual;Informed Consent;innovation;Inpatients;Institutional Review Boards;Intramural Research Program;investigator training;Joints;Lawyers;Leadership;Legal;lens;Marketing;Medical center;Medical Education;Medical Students;meetings;member;mental disorder prevention;Mental Health;mental health education;Mission;Monitor;multidisciplinary;National Institute of Mental Health;neurodevelopment;Neuropsychology;neuroregulation;novel therapeutics;outpatient facility;outreach program;Participant;participant enrollment;Patient Recruitments;patient safety;Patients;Personal Communication;Personal Satisfaction;Pharmacy facility;Physicians;Police;Policies;Postdoctoral Fellow;Preparation;Procedures;Process;product development;programs;Protocols documentation;Provider;Psychiatrist;Psychiatry;Psychology;Psychoses;Qualifying;recruit;Regulation;Reporting;Research;Research Infrastructure;Research Personnel;Research Support;Research Training;Resources;response;Review Committee;Risk;Safety;safety practice;Science Policy;screening;Services;Sleep;social media;Strategic Planning;Structure;Students;suicidal risk;System;tenure track;Training;Training Activity;Training and Education;Training Programs;Translational Research;trend;United States National Institutes of Health;Visit;volunteer;web site;webinar;whole genome;Work;working group

PROJECT_TITLE: NIMH Office of the Clinical Director-Core Activities


NIH_SPENDING_CATS: Neurosciences;Patient Safety

PROJECT_TERMS: Accreditation;Adherence;Adverse event;allied health education;Area;Award;Biopsy;Budgets;Career Transition Award;Caring;Childhood;Clinic;Clinical;clinical care;clinical center;Clinical Data;Clinical Investigator;clinical practice;Clinical Protocols;Clinical Research;Clinical Research Protocols;Clinical Trials;Clinical Trials Unit;Collaborations;Communication;Competence;Conduct Clinical Trials;Consent;Consult;Consultations;continuing medical education;Contracts;Credentialing;Data Analyses;design;Development;Devices;Diagnostic tests;Documentation;early phase clinical trial;Education;Educational Activities;Electroencephalography;Emergency Situation;Ensure;Epilepsy;Ethics;experience;Fellowship;Foundations;Funding;Future;Goals;Good Clinical Practice;Grant;Health;Health Personnel;high standard;Hospitals;Human Resources;human subject;human subject protection;imaging scientist;individual patient;Institution;inter-institutional;Internships;Intramural Research Program;Intraoperative Monitoring;Investigation;Investigational Drugs;Journals;Licensing;Magnetic Resonance Imaging;Medical;medical specialties;Medical Students;meetings;Mission;Monitor;Morbidity - disease rate;mortality;multidisciplinary;Muscle;National Institute of Neurological Disorders and Stroke;Nervous System Disorder;neuroAIDS;Neurodegenerative Disorders;neuroimmunology;Neurologic;Neurological Nursing;Neurology;Neuropsychological Tests;Neurosciences;Neurosciences Research;Nursing Faculty;Nursing Staff;Online Systems;Parkinson Disease;Participant;Patient Care;patient safety;Patients;Pediatric Neurology;Periodicals;Physicians;Policies;Principal Investigator;Process;profession allied to medicine;Professional Organizations;programs;prospective;protocol development;Protocols documentation;quality assurance;Recommendation;recruit;Recruitment Activity;Research;Research Methodology;Research Personnel;Research Training;Residencies;Resource Sharing;Resources;Review Committee;Rotation;Safety;Schedule;Services;sound;symposium;System;Training;training opportunity;Training Programs;Travel;United States National Institutes of Health;University Hospitals;Work

PROJECT_TITLE: NINDS Office of the Clinical Director


NIH_SPENDING_CATS: Acquired Cognitive Impairment;Alzheimer's Disease Related Dementias (ADRD);Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD);Aphasia;Brain Disorders;Clinical Research;Dementia;Frontotemporal Dementia (FTD);Genetics;Neurodegenerative;Neurosciences;Precision Medicine;Rare Diseases

PI_NAMEs: KWAN, JUSTIN  (contact)

PROJECT_TERMS: Affect;Amyotrophic Lateral Sclerosis;Cell Physiology;Clinic;Clinical;Clinical assessments;clinical phenotype;Clinical Research;Cognitive;cognitive testing;Collaborations;Collection;Complex;corticobasal syndrome;Defect;Diagnosis;Disease;DNA Sequence Alteration;Eligibility Determination;Epigenetic Process;Family;Frontotemporal Dementia;Functional Imaging;Future;Gene Mutation;gene product;Genes;Genetic;Health Personnel;Image;individual patient;interest;Knowledge;Laboratories;Language;Leukapheresis;Link;MAPT gene;Molecular;molecular imaging;motor symptom;multidisciplinary;mutant;nervous system infection;Neurodegenerative Disorders;Neurologic Symptoms;Neurologist;Neurology;Participant;Pathology;Patients;phenomenological models;Physicians;precision medicine;Primary Progressive Aphasia;Procedures;Progressive Supranuclear Palsy;protein TDP-43;Protocols documentation;Questionnaires;Registries;Research;research clinical testing;Research Personnel;research study;symposium;Symptoms;United States National Institutes of Health;Update

PROJECT_TITLE: Complex Neurodegenerative Disorders Clinic


ACTIVITY: ZIE

NIH_SPENDING_CATS: Behavioral and Social Science;Brain Disorders;HIV/AIDS;Mental Health;Mental Illness;Neurosciences;Pediatric

PROJECT_TERMS: Academia;Accreditation;Achievement;Adolescent Psychiatry;Adult;Ally;American;Autoimmune;Award;Behavioral;Brain Diseases;Brain imaging;burnout;career;career development;Child;Child Psychiatry;Clinical;clinical center;Clinical Psychology;Clinical Research;clinical training;computational neuroscience;Consultations;Counseling;Development Plans;Doctor of Philosophy;doctoral student;Employee;Endocrinology;Evaluation;experience;Exposure to;externship;Faculty;falls;Fellowship;Fellowship Program;Foundations;Future;Goals;graduate medical education;graduate student;hands on research;Healthcare;hospice environment;Hospitals;Image;Individual;Industry;Information Dissemination;innovation;Intelligence Tests;interest;Interview;Intramural Research;Intramural Research Program;Joints;Lead;Learning;lectures;Major Mental Illness;Maryland;Massachusetts;Medical center;Medical Education;Medical Research;medical specialties;Medical Students;Memory;Mental Health;Mentors;Mentorship;Methodology;Molecular;National Institute of Mental Health;Neurobiology;neurodevelopment;neurogenetics;Neuropsychology;neuroregulation;Neurosciences;Neurosciences Research;novel;novel therapeutics;Nurse Practitioners;outreach;Palliative Medicine;pandemic disease;Personal Satisfaction;Persons;pharmacologic;Physicians;Positioning Attribute;Post Graduate Year;Principal Investigator;programs;Psychiatric epidemiology;Psychiatrist;Psychiatry;Psychologist;Psychology;Psychometrics;Psychopharmacology;Psychotherapy;Puerto Rico;Qualifying;recruit;Reporting;Research;Research Personnel;Research Training;Residencies;Resources;Rotation;Scholars Program;scientific organization;Series;Services;severe mental illness;Site;skills;Sleep;Social Workers;Sorting;statistics;Student Selections;Students;Testing;Time;Training;training opportunity;Training Programs;Training Support;Transcranial magnetic stimulation;United States;United States Food and Drug Administration;United States National Institutes of Health;Universities;University Hospitals;virtual;Visit;Washington;Wisconsin;Work;Writing

PROJECT_TITLE: Psychiatry Clinical Research Training-NIMH Office of the Clinical Director