NIH_SPENDING_CATS: Biotechnology;Genetics

PI_NAMEs: ARAVIND, L  (contact)

PROJECT_TERMS: Amino Acids;analog;Apoptosis;ATP phosphohydrolase;ATPase Domain;Back;Bacteria;Bacteriophages;Binding;Biological;biological adaptation to stress;Biological Process;Biology;Biotechnology;Calcineurin;Cells;Clustered Regularly Interspaced Short Palindromic Repeats;Collaborations;comparative genomics;Complex;Computer Analysis;Conflict (Psychology);Coupled;Cytosine;Discrimination;DNA;DNA Binding;DNA Binding Domain;DNA Restriction Enzymes;Down-Regulation;Elements;Environment;Enzymes;Eukaryota;gene conservation;Gene Modified;Genes;genetic information;Genetic Transcription;Genome;genome editing;Guanosine Triphosphate Phosphohydrolases;Heat-Shock Proteins 70;Heat-Shock Proteins 90;Homeostasis;Housekeeping;Human;Immune;Immune system;Immunity;inorganic phosphate;Intercept;interoperability;Life;Logic;Lyme Disease;Magnesium;Manganese;Membrane;Metals;Methyltransferase;Microscopic;Modification;Molecular;Molecular Mechanisms of Action;Names;National Institute of Child Health and Human Development;Neighborhoods;novel;nuclease;Nucleic Acids;nucleobase;Nucleotides;Organism;pathogen;Pathway interactions;Peptide Signal Sequences;periplasm;phosphorothioate;Phosphotransferases;Post-Transcriptional Regulation;Prokaryotic Cells;Proteins;Proteolysis;Pump;Reagent;recruit;Regulation;replicator;Research;Research Personnel;response;Scanning;science education;Second Messenger Systems;segregation;Signal Transduction;Source;Specificity;Stimulus;Structure;Suicide;syntax;System;Systems Biology;Tertiary Protein Structure;Testing;Toxin;Universities;Variant;Vertebral column;Viral;Virus;Water;whole genome;Whole Organism;Wisconsin;Work

PROJECT_TITLE: Evolutionary Analysis and Comparative Genomics of Protein Superfamilies


ACTIVITY: ZIA

ADMINISTERING_IC: MH

ARRA_FUNDED: N

FUNDING_MECHANISM: INTRAMURAL RESEARCH

IC_NAME: NATIONAL INSTITUTE OF MENTAL HEALTH

NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Mental Health;Neurosciences

ORG_NAME: NATIONAL INSTITUTE OF MENTAL HEALTH

PI_NAMEs: RICHMOND, BARRY J (contact)

PROJECT_TERMS: Address;Behavior;Behavioral;Brain;Brain region;Canis familiaris;Categories;Code;cognitive process;Depressed mood;design;Electrodes;Elements;Emotional disorder;Esthesia;Event;Failure;Family member;Feeling;Felis catus;Food;Grouping;Image;Individual;Inferior;information processing;irritation;Learning;Lesion;Measures;Memory;Monkeys;Movement;neural;Neurons;nonhuman primate;parallel processing;Perception;Physiologic pulse;Population;Primates;Process;Psyche structure;response;Role;sensory stimulus;Series;Stimulus;Temporal Lobe;Utah;Visual;visual coding;visual memory;Visual Perception;visual stimulus

PROJECT_TITLE: Neural Coding of Visual Stimuli


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Chronic Pain;Genetics;Mental Health;Neurosciences;Pain Research

PI_NAMEs: EIDEN, LEE E. (contact)

PROJECT_TERMS: allodynia;Amines;Amygdaloid structure;Area;Aversive Stimulus;Behavior;Behavioral;behavioral impairment;behavioral outcome;behavioral plasticity;behavioral response;Biochemical;biological adaptation to stress;Brain;Ca(2+)-Calmodulin Dependent Protein Kinase;Calcium;Calendar;Cells;Chemicals;Chronic;Code;Collaborations;combinatorial;conditioned fear;conditioned place preference;Conditioned Stimulus;conditioning;Coupled;CRH gene;Cues;Cyclic AMP;Cyclic AMP-Dependent Protein Kinases;Dependence;Development;Dopamine;Dopamine D1 Receptor;Electrophysiology (science);Elements;Endocrine;Event;FOS gene;Foundations;Freezing;Fright;G-Protein-Coupled Receptors;gene induction;Genes;Genetic;genetic signature;Glutamates;hippocampal pyramidal neuron;Hippocampus;Hypothalamic structure;Immediate-Early Genes;Impairment;information processing;Interneurons;Interruption;Intracellular Signaling Proteins;Investigation;Knock-out;Laboratories;Learning;Link;Mediating;Messenger RNA;Molecular;Mus;National Center for Complementary and Integrative Health;National Institute of Mental Health;nerve injury;Neuroendocrine Cell;neuronal circuitry;Neurons;Neuropeptides;neuropsychiatric disorder;neuroregulation;Neurosciences;neurotransmission;Neurotransmitters;novel;Nucleus Accumbens;PACAPR-1 protein;Pain;pain sensation;paraventricular nucleus;Pathway interactions;Peripheral nerve injury;Pharmaceutical Preparations;Phenocopy;Phenotype;Phosphorylation;pituitary adenylate cyclase activating polypeptide;Play;Population;postsynaptic;Process;Prosencephalon;Protein Kinase;Publications;Publishing;RAPGEF2 gene;receptor;Receptor Activation;Reporting;response;restraint;restraint stress;reward processing;Role;Scientist;Shock;Signal Pathway;Signal Transduction;small molecule;Stimulant;Stimulus;Stress;Synapses;Synaptic plasticity;Syndrome;System;Testing;Transcription Initiation;Transducers;transmission process;Universities;Wild Type Mouse;Work

PROJECT_TITLE: Chemical Coding of Neurotransmission


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biotechnology;Brain Disorders;Genetics;Mental Health;Neurosciences

PI_NAMEs: GERFEN, CHARLES R (contact)

PROJECT_TERMS: Affect;Amygdaloid structure;Animal Behavior;Animal Model;Anterior;Anxiety;Area;arm;association cortex;Atlases;Attention deficit hyperactivity disorder;Axon;Bacterial Artificial Chromosomes;Basal Ganglia;Basal Ganglia Diseases;Behavior;Behavior Control;Bilateral;Brain;brain circuitry;Brain imaging;Brain region;California;Cerebral cortex;clinical movement disorder;Collaborations;Communities;Complex;Contralateral;Corpus striatum structure;Cre driver;Decision Making;Development;Disease;Dopamine;Dopamine D2 Receptor;dopaminergic neuron;Engineering;Enterobacteria phage P1 Cre recombinase;Enzymes;Equilibrium;Esthesia;Experimental Designs;Eye;Face;fear memory;Feedback;feeding;frontal lobe;Functional disorder;Funding;Gene Expression Regulation;Genes;Genetic Engineering;Genetic Techniques;Glutamates;Image;information model;information organization;inhibitory neuron;insight;interest;Ipsilateral;L-DOPA induced dyskinesia;Label;Laboratories;Laboratory Research;Lesion;Light;LoxP-flanked allele;Maps;Mediating;Mental disorders;Methods;Microscopy;Midbrain structure;Molecular Genetics;Motor;Motor Activity;motor behavior;Motor Cortex;Movement;Movement Disorders;Mus;National Institute of Drug Abuse;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;National Institute on Alcohol Abuse and Alcoholism;neural;neural circuit;Neural Pathways;Neuroanatomy;Neurologic Dysfunctions;Neuromodulator;Neuronal Plasticity;Neurons;Neurosciences;Neurosciences Research;Neurotransmitter Receptor;optogenetics;Outcome;Output;Paper;Parkinson Disease;Pathway interactions;Pattern;Pennsylvania;Physiological;Population;postsynaptic;Process;programs;Prosencephalon;protein activation;Protein Kinase;Psychotropic Drugs;Publications;Publishing;rabies viral tracing;Regulation;Research;Research Personnel;response;Role;San Francisco;segregation;Sensory;sensory cortex;sensory integration;Signal Pathway;Signal Transduction Pathway;Somatosensory Cortex;superior colliculus Corpora quadrigemina;Synapses;System;Techniques;Tectum Mesencephali;Thalamic Nuclei;Thalamic structure;Time;tool;transcription factor;Transcriptional Activation;Transgenic Mice;transmission process;United States National Institutes of Health;Universities;Viral Vector;Visual Cortex;visual information;Visual Motion;Work

PROJECT_TITLE: Functional Organization of the Cerebral Cortex and Basal Ganglia


NIH_SPENDING_CATS: Aging;Behavioral and Social Science;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Depression;Estrogen;Menopause;Mental Health;Mental Illness;Neurosciences;Women's Health Research

PI_NAMEs: SCHMIDT, PETER  (contact)

PROJECT_TERMS: Accounting;Affective;Agonist;animal data;anti-depressive agents;Anti-Inflammatory Agents;Behavior;Behavioral;Biological;Blinded;Blood;Brain;burden of illness;Cardiovascular Diseases;cardiovascular disorder risk;Cardiovascular system;Cell Line;Characteristics;Circadian Rhythms;Clinic Visits;Clinical;Clinical Protocols;Clinical Research;Cognition;Communities;CXCL10 gene;Data;dehydroepiandrosterone;dementia risk;density;depressive symptoms;Development;Diagnostic;Direct Costs;Double-Blind Method;Early-life trauma;effective therapy;Endometrial;Enzymes;epidemiology study;ESR1 gene;Estradiol;Estrogen deficiency;Estrogen Receptor 2;Estrogen Therapy;Event;experience;Experimental Designs;Facilities and Administrative Costs;Family;Formulation;functional genomics;Genes;Genetic Transcription;Goals;Growth;hearing impairment;High Risk Woman;Hormonal;hormonal signals;hormone therapy;Hormones;Hot flushes;hypothalamic-pituitary-adrenal axis;Impaired cognition;in vitro Model;Inflammatory;Interview;Life;life span;Link;longitudinal, prospective study;lymphoblastoid cell line;Major Depressive Disorder;Measures;Medical;member;menopausal hormone therapy;Menopause;Menstruation;Mental Depression;Metabolic syndrome;Metabolism;middle age;Midlife women;minor depressive disorder;modifiable risk;Monitor;Mood Disorders;mood symptom;Moods;Morbidity - disease rate;mortality;negative mood;Neurosecretory Systems;neurotransmission;NF-kappa B;novel;novel therapeutic intervention;novel therapeutics;open label;Osteoporosis;Outcome;Ovarian;Ovarian aging;oxysterol 7-alpha-hydroxylase;Participant;Pathway Analysis;Pattern;Perimenopause;Placebo Control;Placebos;Plasma;Postmenopause;Predisposition;Premenopause;Presbycusis;Prevalence;prevent;Progestins;proliferative phase Menstrual cycle;psychobiology;Randomized;randomized placebo controlled trial;Recording of previous events;Recurrence;recurrent depression;Regulation;RELA gene;Relative Risks;Reporting;reproductive;reproductive senescence;Research Design;response;Risk;Risk Marker;Role;Safety;Sampling;Signal Transduction;single episode major depressive disorder;Source;steroid hormone;Steroids;suicide rate;Symptoms;Therapeutic;Time;Transcript;transcriptome;vasomotor symptoms;Withdrawal;Woman;Women's Health;Women's mortality;Work

PROJECT_TITLE: Psychobiology and Treatment of Perimenopausal Mood Disorders


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Clinical Research;Mental Health;Neurosciences;Nutrition

PI_NAMEs: MARTIN, ALEX  (contact)

PROJECT_TERMS: Address;Animals;animation;Behavior;Behavioral;Biology;Brain;Brain imaging;Brain region;Candy;Categories;Clinical Protocols;Code;Cognition;Communication;Complex;Coupled;Data;Democracy;Electroencephalography;Emotions;experience;falls;Food;Food Preferences;food quality;Foundations;Freedom;frontier;Functional Magnetic Resonance Imaging;functional magnetic resonance imaging/electroencephalography;Future;Goals;Human;Imagination;imaging modality;Impairment;implicit memory;improved;insight;Insula of Reil;Journals;Justice;Knowledge;Language;Learning;Magnetoencephalography;Maps;Measures;Memory;multimodality;Nature;neural;neural circuit;Neurobiology;neuromechanism;neuropsychiatric disorder;Neurosciences;object recognition;Participant;Performance;Population;Process;Property;Psyche structure;Psychology;Research;Resolution;Retrieval;Semantic memory;Sensory;Series;social;social cognition;Social Interaction;Stimulus;Structure;System;Taste Perception;tool;United States National Academy of Sciences;Visual Perception;Work

PROJECT_TITLE: The Neural Foundations for Memory and Social Cognition in the Human Brain


PROJECT_TERMS: Ablation;Amygdaloid structure;Anterior;Behavior;Behavioral;Behavioral Mechanisms;behavioral study;Brain;brain reward regions;Cells;cost;Decision Making;Drug abuse;drug of abuse;Emotional;emotional stimulus;Equilibrium;experimental study;Feedback;Feeling hopeless;Hunger;Image;Individual;Learning;Mental Depression;Mental disorders;Molecular;Monkeys;Motivation;neural;neuromechanism;Neurons;neurotransmission;Pathway interactions;Performance;Play;Prefrontal Cortex;Process;putamen;receptor;Reporter;Reporter Genes;Rewards;Role;Sensory;sensory stimulus;Signal Transduction;social;Stimulus;stimulus processing;System;Theoretical Studies;Thirst;transmission process;Virus;Work

PROJECT_TITLE: Neural Mechanisms of Motivation and Reward


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Genetics;Mental Health;Mental Illness;Neurosciences;Schizophrenia;Serious Mental Illness

PI_NAMEs: BERMAN, KAREN FAITH (contact)

PROJECT_TERMS: Address;Affect;Agreement;Antipsychotic Agents;Automobile Driving;Autopsy;Biological Assay;Biological Markers;Blood flow;Brain;brain tissue;case control;Cerebrovascular Circulation;Clinical;clinical care;Clinical Research;Cognition;Cognitive;cognitive function;cohort;Cohort Studies;collected works;Corpus striatum structure;Data;Data Collection;data reduction;Data Set;Databases;Development;Dimensions;Disease;Dopamine;Dopamine Receptor;dopamine system;dopaminergic neuron;drug withdrawal;effective therapy;Etiology;experimental study;Foundations;Functional disorder;Functional Magnetic Resonance Imaging;Gene Expression;Generations;Genes;Genetic;genetic association;Genetic Risk;genome wide association study;genome-wide;Genotype;Goals;Heritability;Heterogeneity;Human;Image;imaging modality;in vivo evaluation;indexing;Individual;innovation;Inpatients;Intramural Research Program;longitudinal positron emission tomography;Magnetic Resonance Imaging;Magnetoencephalography;Measurement;Measures;Methods;millisecond;Modeling;Molecular;Molecular Target;Motor;multimodality;National Institute of Mental Health;Nature;neural;neural circuit;neural correlate;Neurobiology;neurochemistry;Neurocognitive;neurocognitive test;neuroimaging;Neurons;neurophysiology;neuropsychiatric disorder;neuropsychiatry;Neurotransmitters;Noise;novel;Outcome;Oxygen;Parkinson Disease;Pathogenesis;Patients;personalized medicine;Pharmaceutical Preparations;Phenotype;Placebos;polygenic risk score;Positron-Emission Tomography;postsynaptic;Prefrontal Cortex;presynaptic;Procedures;Process;programs;Protocols documentation;radioligand;receptor;Regulation;Reporting;Research;research facility;Resolution;response;reward anticipation;Rewards;risk variant;Schizophrenia;schizophrenia risk;Series;Short-Term Memory;Signal Transduction;spatiotemporal;Symptom Burden;Symptoms;System;Task Performances;Testing;theories;therapeutic target;Tissue Banks;translational genetics;transmission process;treatment response;Update;volunteer;Water;Work

PROJECT_TITLE: Imaging of Neuropsychiatric Disorders with Developmental and Genetic Mechanisms


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Contraception/Reproduction;Depression;Estrogen;Genetics;Mental Health;Mental Illness;Neurosciences;Pediatric;Rare Diseases;Serious Mental Illness;Women's Health Research

PROJECT_TERMS: 7q11.23;8 year old;Adolescent;Adrenal Glands;Adrenal hormone preparation;Adult;Affect;Age;Age at Menarche;Androgens;Anterior;Autopsy;Behavior;Behavior Disorders;Behavioral;Biological;Brain;brain based;brain circuitry;Brain imaging;Child;cingulate cortex;Clinical;Cognition;Cognition Disorders;Cognitive;cognitive function;cognitive neuroscience;Collaborations;comorbidity;Complex;Corpus striatum structure;cost;course development;Data;Data Set;Decision Making;Dedications;Dehydroepiandrosterone Sulfate;Delayed Puberty;Dependence;Development;developmental disease;Dimensions;Dopamine;Dopamine Receptor;Endocrine;Endocrinology;Environment;Environmental Risk Factor;Epidemiology;Estradiol;Estrogens;Event;experimental study;Face Processing;Failure;Functional disorder;Gene Dosage;gene interaction;General Population;Genes;Genetic;Genetic Transcription;genome wide association study;genomic locus;Gonadal Hormones;Growth;Health;Hormonal;Hormonal Change;Hormones;Human;Image;imaging modality;Impairment;improved;Individual;insight;interest;Investigation;Knowledge;life span;Light;Link;longitudinal design;Longitudinal Studies;Magnetic Resonance;Magnetic Resonance Imaging;Measurement;Measures;Menarche;Menstruation;Mental Depression;Mental disorders;Molecular;Multimodal Imaging;multimodal neuroimaging;Nature;neural;neural circuit;Neurobiology;neurochemistry;neurodevelopment;Neuroendocrinology;neurogenetics;neuroimaging;neuropsychiatry;Neuropsychological Tests;Neuropsychology;novel;Onset of illness;operation;Ovarian Ablation;Ovarian Steroid Hormone;Pattern;Persons;Pharmaceutical Preparations;Phenotype;Pituitary Gland;Plasma;Play;Positron-Emission Tomography;Postpartum Period;postsynaptic;premenstrual dysphoric disorder;prepuberty;presynaptic;primary ovarian insufficiency;Progesterone;Protocols documentation;Psychoses;pubertal timing;Puberty;Resources;reward processing;Rewards;Risk;Role;Scientific Inquiry;severe mental illness;Sex Differences;Syndrome;System;Testing;Testosterone;Time;Translating;Variant;Williams Syndrome;Woman;Work

PROJECT_TITLE: Neuroimaging of Brain Circuits and Molecular Mechanisms in Normal Cognition


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Mental Health;Neurosciences

PI_NAMEs: MURRAY, ELISABETH A (contact)

PROJECT_TERMS: Amnesia;Amygdaloid structure;Animals;arm;base;Bilateral;Brain;Collection;Computers;design;Disputes;Effectiveness;Episodic memory;Event;excitotoxicity;Failure;Familiarity;Feeling;frontal lobe;Gambling;Goals;habituation;Hippocampus;Human;Impairment;Knowledge;Lesion;Life;Life Experience;Location;long term memory;Measures;Medial;Memory;Memory impairment;memory process;memory recognition;Meta-Analysis;Motivation;neural;object recognition;Paired Comparison;Patients;Perceptual learning;preference;Process;reward processing;ROC Curve;Rodent;Sampling;Semantic memory;Severities;Short-Term Memory;skills;Stimulus;Structure;Techniques;Testing;Thalamic structure;Time;touchscreen;Visual;visual memory;Weight;Work

PROJECT_TITLE: Neural Substrates of Stimulus Recognition and Association Memory


NIH_SPENDING_CATS: Anxiety Disorders;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Depression;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Pediatric;Serious Mental Illness

PI_NAMEs: PINE, DANIEL  (contact)

PROJECT_TERMS: Adolescent;Adult;Animal Model;Anxiety;Anxiety Disorders;anxious;Area;Attention;attentional bias;attentional modulation;Behavior;Biological;Biological Markers;Brain;Brain imaging;Brain region;Child;Child Welfare;Childhood;Clinical;clinical practice;Clinical Trials;Cognitive Therapy;cognitive training;Collaborations;Data;Depressive disorder;effective therapy;efficacy evaluation;Emotional;Enrollment;Exhibits;Extinction;Extramural Activities;Fright;Functional disorder;Functional Magnetic Resonance Imaging;Health;Impairment;Individual;Individual Differences;insight;interest;International;Journals;large datasets;Leadership;Life;Magnetoencephalography;Major Depressive Disorder;Measures;Memory;Mental Depression;Mental disorders;Methods;Mood Disorders;National Institute of Mental Health;neural;neural circuit;neural correlate;Neurocognitive;Neuropsychology;Neurosciences;next generation;novel;novel therapeutics;Paper;Participant;Pathway interactions;patient response;Patients;Pattern;Play;Prediction of Response to Therapy;Protocols documentation;Psychopathology;Public Health;Publications;Publishing;Randomized, Controlled Trials;Recruitment Activity;Reporting;Research;response;Role;Site;Standardization;Stimulus;Symptoms;Syndrome;Techniques;Testing;therapy resistant;Training;Transcranial magnetic stimulation;Treatment outcome;treatment research;treatment response;United States National Institutes of Health;web site;Work

PROJECT_TITLE: fMRI Studies of Pediatric Mood and Anxiety Disorders


NIH_SPENDING_CATS: Anxiety Disorders;Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Depression;Mental Health;Mental Illness;Neurosciences;Pediatric;Prevention

PROJECT_TERMS: Address;Adolescence;Adolescent;Adult;Amygdaloid structure;Anxiety;Anxiety Disorders;anxiety symptoms;Area;behavior prediction;Behavioral;Behavioral inhibition;Biological;Brain;Brain imaging;Child;Childhood;Classification;cohort;Collaborations;Corpus striatum structure;Data;Data Collection;depressive symptoms;Development;developmental disease;early childhood;Electrophysiology (science);Emotional;experience;Exposure to;Extramural Activities;Functional Magnetic Resonance Imaging;Funding;Goals;Grant;Health;high risk;indexing;Individual;infancy;Infant;insight;International;Investigation;Journals;Lead;Life;Maryland;Measures;Mediating;Medical;Mental Depression;Mental disorders;Mood Disorders;morphogens;Nature;neural;Neurocognitive;novel;Outcome;Paper;Participant;Prefrontal Cortex;Prevention;preventive intervention;programs;prospective;Protocols documentation;psychologic;Psychopathology;Public Health;Publishing;Recording of previous events;Reporting;Research;resilience;Resources;response;reward processing;Risk;Risk Factors;Sampling;SARS-CoV-2 exposure;Series;severe mental illness;social;Societies;Stimulus;Stream;Task Performances;Temperament;Testing;Thinking;transition to adulthood;United States National Institutes of Health;Universities;Washington;Well in self;Work;young adult

PROJECT_TITLE: fMRI Studies of Risk for Mood and Anxiety Disorders in Children


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Biotechnology;Clinical Research;Machine Learning and Artificial Intelligence;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: BANDETTINI, PETER  (contact)

PROJECT_TERMS: Affect;Afterimage;Algorithms;analytical method;Anterior;Arousal;Attention;Auditory;Awareness;Behavioral;Blood Vessels;Brain;Brain Mapping;Characteristics;Classification;Clinical;clinical phenotype;clinical predictors;Clinical Protocols;clinically relevant;Cognition;Cognitive;cognitive neuroscience;Collaborations;Communication;computer scientist;Conscious;constriction;Core Facility;Data;Data Collection;data sharing;denoising;Dependence;detection method;Development;Dreams;Engineering;Event;Excision;experience;Feedback;follow-up;Functional Imaging;Functional Magnetic Resonance Imaging;functional magnetic resonance imaging/electroencephalography;Fusiform gyrus;Goals;gray matter;hemodynamics;Human;Imagery;imaging modality;imprint;improved;independent component analysis;Individual;innovation;insight;Insula of Reil;interest;Intramural Research Program;Laboratories;Machine Learning;Magnetic Resonance Imaging;Magnetoencephalography;Manuscripts;Maps;Measurement;Measures;meetings;mental imagery;method development;Methodology;Methods;Modeling;Monitor;Morphologic artifacts;multimodal neuroimaging;multimodality;multisensory;Names;Nature;Neocortex;neural;neuromechanism;Neurons;Neurosciences;Noise;novel;novel strategies;open source;Participant;Pattern;Peer Review;Perception;Performance;Personality;Phenotype;Physiologic pulse;Physiological;Physiology;Population Study;posters;preservation;Prevalence;Printing;Procedures;Process;Property;Proxy;Publications;Publishing;Pupil;real time monitoring;Reporting;Research;Research Personnel;Resolution;response;Rest;Role;scientific computing;Second Look Surgery;Sensitivity and Specificity;Sensory;sensory integration;sensory mechanism;Series;Signal Transduction;Slide;Societies;spatiotemporal;Statistical Computing;Stimulus;symposium;Technology;temporal measurement;Testing;Thinking;Time;trend;ultra high resolution;United States National Institutes of Health;Vision;Visual;visual imagery;Visual Perception;Work

PROJECT_TITLE: Functional MRI Method Development


PI_NAMEs: CAMERON, HEATHER A (contact)

PROJECT_TERMS: Adult;adult neurogenesis;Affect;approach behavior;Automobile Driving;Behavior;Behavioral;Birth;Brain;Brain region;Curiosities;Development;Environmental Risk Factor;experience;Female;Food;Formulation;Future;Goals;good diet;Growth;hippocampal pyramidal neuron;Hippocampus;Human;interest;Learning;Magnetic Resonance Imaging;male;Maze Learning;Memory;Mood Disorders;Mus;neurogenesis;Neurons;Pathologic;Pathway interactions;Play;Population;preference;Primates;Production;Rattus;Regulation;response;Rewards;Role;Stress;Stressful Event;sugar;Testing;Time;Training;Work

PROJECT_TITLE: Neurogenesis in the Adult Brain


NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Brain Disorders;Mental Health;Mental Illness;Neurosciences

PI_NAMEs: PIKE, VICTOR W (contact)

PROJECT_TERMS: Academia;Affect;Alzheimer's Disease;Animals;Anti-Inflammatory Agents;Anxiety;Aspirin;autism spectrum disorder;Behavior;Binding Sites;Biochemical;Biochemical Process;Biological Models;Biology;biomathematics;Brain;Carbon;carbon emissions;Chemicals;Clinical;clinical application;clinical center;Clinical Research;Collaborations;CSF1R gene;cyclooxygenase 1;cyclooxygenase 2;Cyclotrons;Dementia;design;Development;Diagnosis;Disease;Disease remission;Drug Addiction;drug development;drug discovery;Enzymes;Epilepsy;Evaluation;experimental study;Fluorine;fluoroform;Foundations;Fragile X Syndrome;Functional disorder;genetic technology;Glutamates;Good Manufacturing Process;Human;human subject;hypocretin;Ibuprofen;Image;imaging facilities;Imaging Techniques;improved;insight;interest;International;Investigational New Drug Application;Investigational Therapies;Ions;Label;Laboratories;LRRK2 gene;Macrophage Colony-Stimulating Factor Receptor;Measures;Medicine;Mental Depression;Mental disorders;Metabolism;Methodology;Methods;mild cognitive impairment;Mission;Mitochondria;Modeling;Modernization;Molecular;molecular imaging;molecular site;Monkeys;N-Methyl-D-Aspartate Receptors;N-Methylaspartate;National Institute of Drug Abuse;National Institute of Mental Health;Nature;Nerve Degeneration;neuroimaging;neuroinflammation;Neurologic;neuropsychiatric disorder;neuropsychiatry;neurotransmission;Neurotransmitter Receptor;Neurotransmitters;new therapeutic target;nonhuman primate;novel;Oncology;Organic Chemistry;Pathogenesis;PDE4B;Performance;Pharmaceutical Chemistry;Pharmaceutical Preparations;pharmacologic;Pharmacology;phosphoric diester hydrolase;Phosphotransferases;Physics;Positron;Positron-Emission Tomography;Postdoctoral Fellow;pre-clinical;Production;programs;Property;Prostaglandin-Endoperoxide Synthase;Proteins;Protocols documentation;Psychiatry;Publishing;Radio;Radioactive;Radiochemistry;Radioisotopes;Radiolabeled;Radiopharmaceuticals;radiotracer;receptor;Reporting;Research;response;Rewards;Risk;Rodent;Schizophrenia;Science;Scientist;Sensory Receptors;Source;Specificity;Stroke;Synaptic Vesicles;targeted imaging;Techniques;Therapeutic Intervention;Tracer;Training;Translating;Traumatic Brain Injury;United States Food and Drug Administration;United States National Institutes of Health;Universities;Work

PROJECT_TITLE: PET Radiopharmaceutical Sciences


NIH_SPENDING_CATS: Alcoholism, Alcohol Use and Health;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Brain Disorders;Depression;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Serious Mental Illness;Substance Misuse

PI_NAMEs: INNIS, ROBERT  (contact)

PROJECT_TERMS: Acute;Affinity;alcohol abuse therapy;Alcohol consumption;Alcohol dependence;alcohol exposure;alcohol use disorder;Alcohol withdrawal syndrome;Alcohols;Amyloid beta-Protein;Animal Model;Animals;Annual Reports;anti-depressive agents;Automobile Driving;Binding;Biological Markers;Blood;Brain;Brain imaging;Cell Culture Techniques;Characteristics;Chemicals;Chronic;clinically relevant;Collaborations;comorbidity;comparison control;Contralateral;Control Groups;Cyclic AMP;Cyclic AMP-Dependent Protein Kinases;Data;Depressive disorder;Disease;Dose;Drug Kinetics;Effectiveness;Ensure;Ethanol;Evaluation;experience;follow-up;Genetic Polymorphism;Goals;healthy volunteer;Hour;Human;human subject;Image;improved;in vivo;Individual;Inflammatory;Infusion procedures;inhibitor;Injections;Intoxication;Ketamine;Laboratories;Laboratory Finding;Legal;Lipopolysaccharides;Major Depressive Disorder;Measurement;Measures;Methods;Modeling;molecular imaging;Mood Disorders;National Institute of Drug Abuse;National Institute on Alcohol Abuse and Alcoholism;neuroinflammation;neuropsychiatric disorder;nonhuman primate;novel;Participant;Pathway interactions;patient population;Patients;Pattern;PDE4B;pharmacologic;phosphodiesterase IV;Phosphorylation;Positron-Emission Tomography;preference;procedure safety;Process;Proteins;Radiolabeled;radioligand;radiotracer;Rattus;recruit;Reproducibility;Research;Resistance;Rodent;Rolipram;Saline;Scanning;Schizophrenia;Second Messenger Systems;Selective Serotonin Reuptake Inhibitor;severe mental illness;Signal Transduction;single episode major depressive disorder;sobriety;Sum;Testing;Therapeutic;Time;Tracer;uptake;Withdrawal Symptom;Work

PROJECT_TITLE: Translational Evaluation of PET Radiotracers


NIH_SPENDING_CATS: Mental Health;Neurosciences

PI_NAMEs: PLENZ, DIETMAR  (contact)

PROJECT_TERMS: Action Potentials;Animals;awake;Behavior;Biological Markers;Brain;brain abnormalities;brain cell;Cell Communication;Clinical Data;Cognition;Communication;Complex;Computer Simulation;Correlation Studies;Crackles;Data;detection method;Development;Diagnosis;Disease;Entropy;Equilibrium;excitatory neuron;Exhibits;Fire - disasters;frontal lobe;Goals;Grain;Human;Image;In Vitro;in vivo;information processing;inhibitory neuron;insight;interdisciplinary approach;International;Intramural Research Program;Ising model;Laboratories;large datasets;Laws;Mediating;Mental disorders;Methods;model building;Modeling;Monitor;Monkeys;Movement;multiphoton imaging;Mus;Neocortex;Nervous System Disorder;Neurons;Neurosciences;Noise;Pattern;Perception;Phase;Phase Transition;Physics;Population;Process;Publishing;Rattus;Reporting;Research;Research Support;Rest;Rodent;Role;Sampling;spatiotemporal;System;Temperature;Testing;theories;Thermodynamics;Time;Translational Research;two-photon;United States National Institutes of Health;Work

PROJECT_TITLE: Neuronal Avalanches in the Neocortex


NIH_SPENDING_CATS: Behavioral and Social Science;Mental Health;Neurosciences

PI_NAMEs: WHITE, BENJAMIN H (contact)

PROJECT_TERMS: Achievement;Adult;Alleles;Anatomy;Animals;Anterior;Anxiety Disorders;Behavior;Behavioral;Behavioral Mechanisms;Biological Metamorphosis;Bipolar Disorder;Body Regions;Brain;brain cell;Brain region;calcium indicator;Cells;Custom;Depressive disorder;Development;Drosophila genus;Drosophila melanogaster;Environment;Exclusion;Exhibits;Exons;exoskeleton;Face;fly;Genes;Genetic;Goals;Homeobox Genes;homeodomain;Hormonal;hormonal signals;Hormones;Human;Image;Insecta;insight;Instruction;intein;interest;Investigation;Knowledge;Laboratories;Light;Maps;Mediating;Mental disorders;Methods;Microscope;Microscopy;Molting;Motivation;Motor;Motor Neurons;Motor output;Movement;Muscle;Nervous System;neural;neural circuit;neural network;neuromechanism;Neuromodulator;neuron component;neuronal patterning;Neurons;Neurophysiology - biologic function;neuroregulation;Neurosciences;Obsessive-Compulsive Disorder;operation;Organism;Output;Paper;Pattern;Phase;Play;Positioning Attribute;Preparation;Process;Programming Languages;programs;Protein Truncation;Proteins;Publishing;Recurrence;Research;Research Personnel;Resolution;response;Role;Schizophrenia;Signal Transduction;Specific qualifier value;Study models;Technology;technology development;Time;tool;transcription factor;transgene expression;Wing;Work;Writing

PROJECT_TITLE: Identifying Neural Substrates of Behavior in Drosophila Melanogaster


NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Mental Health;Mental Illness;Neurosciences

PI_NAMEs: SHEN, JUN  (contact)

PROJECT_TERMS: Address;Amino Acids;Autopsy;Biological;Blood flow;Brain;Brain Diseases;brain metabolism;Carbon;cell type;Cells;Cerebral cortex;Chemicals;Choline;Clinical;clinical application;cognitive function;Coupling;Creatine;Custom;Data Set;Dimensions;Emotions;Environment;enzyme activity;Enzymes;frontal lobe;Functional disorder;gamma-Aminobutyric Acid;Glutamates;Glutamine;Glutathione;Goals;Human;imaging study;Imaging Techniques;in vivo;in vivo magnetic resonance spectroscopy;Individual;innovation;insight;Label;Link;magnetic field;Magnetic Resonance Imaging;Magnetic Resonance Spectroscopy;Maps;Measurement;Measures;Medial;Mental Depression;Mental disorders;Metabolic;metabolic abnormality assessment;Methods;Molecular;Monitor;myoinositol;N-acetylaspartate;neurochemistry;Neuroglia;Neurons;neuropsychiatric disorder;neurotransmission;Neurotransmitters;Non-Invasive Detection;novel;Pathology;Pattern;Personality;Pharmaceutical Preparations;Phosphocreatine;Phosphorus;Play;Prefrontal Cortex;Protocols documentation;Protons;radio frequency;Relaxation;Research;Resolution;Role;Schizophrenia;Signal Transduction;Social Interaction;Synapses;Techniques;Technology;Time;Tissue Sample

PROJECT_TITLE: Magnetic Resonance Spectroscopy and Imaging Studies of Brain Functions


NIH_SPENDING_CATS: Anxiety Disorders;Behavioral and Social Science;Bioengineering;Bipolar Disorder;Brain Disorders;Cardiovascular;Chronic Pain;Clinical Research;Depression;Genetics;Headaches;Major Depressive Disorder;Mental Health;Mental Illness;Migraine;Neurosciences;Pain Research;Pediatric;Physical Activity;Prevention;Serious Mental Illness;Sleep Research

PI_NAMEs: MERIKANGAS, KATHLEEN R (contact)

PROJECT_TERMS: 17 year old;Accelerometer;actigraphy;Address;Adult;Affect;Affective;Age;Algorithms;Anxiety;Anxiety Disorders;anxiety spectrum disorders;anxious;Assessment tool;Biological;Biological Factors;Bioperiodicity;Bipolar Disorder;Bipolar I;Bipolar II;Breeding;Cardiovascular Diseases;Cardiovascular Physiology;Cardiovascular system;Child;Circadian Rhythms;Clinical;clinical center;clinical phenotype;Cognitive;cognitive testing;cohort;Collaborations;Communities;community setting;comorbidity;comparison control;computer program;computerized;dashboard;Data;data acquisition;Data Analyses;Data Collection;data management;Data Science;Depressed mood;Development;Diagnostic;diagnostic criteria;diaries;Dimensions;Disease;Disease susceptibility;disorder subtype;DSM-V;Dual-Energy X-Ray Absorptiometry;Early Intervention;Ecological momentary assessment;Electronics;endophenotype;Enrollment;Etiology;Evaluation;Event;Evolution;Exercise;Exercise Test;Exhibits;Family;family structure;Family Study;First Degree Relative;follow-up;Future;Genetic;genetic epidemiology;Goals;Headache;Health;heuristics;high risk;Homeostasis;immune function;implementation measures;improved;Individual;Inpatients;instrument;Intervention;Interview;Investigation;Laboratories;Lead;Life;life span;Light;Link;longitudinal design;Magnetic Resonance Imaging;Major Depressive Disorder;Measures;Medical;Medical History;Mental disorders;Mental Health;Metabolic;method development;Methodology;Methods;Migraine;Modeling;Mood Disorders;Moods;Motor Activity;National Institute of Mental Health;Natural History;Neurologic Examination;Neuropsychology;Nomenclature;novel;novel strategies;Operations Research;Outpatients;Pain;Participant;Pathology;Patient Recruitments;Patient Self-Report;Pattern;Personality;Persons;Phase;phenomenological models;Phenotype;physical conditioning;Physical Examination;Physiological;Prevention;proband;Procedures;Process;prognostic;prospective;Protocols documentation;Psyche structure;Psychiatry;Psychology;Psychopathology;Psychophysiology;psychosocial;Public Health;Recontacts;Recording of previous events;recruit;Reporting;Research;Research Personnel;Resolution;Risk;Role;Saliva;Sampling;Series;Sleep;Sleep Disorders;sleep pattern;sleep quality;smartphone based assessment;Specificity;Spouses;stability testing;Stress;Structure;Subgroup;Substance Use Disorder;Suicide;Surveys;symptom cluster;Symptoms;Syndrome;System;Testing;Time;tool;transmission process;United States National Institutes of Health;Update;user-friendly;Visualization;Work

PROJECT_TITLE: Family Study of Affective and Anxiety Spectrum Disorders


NIH_SPENDING_CATS: Biotechnology;Bipolar Disorder;Brain Disorders;Depression;Genetic Testing;Genetics;Human Genome;Mental Health;Mental Illness;Neurosciences;Prevention;Schizophrenia;Serious Mental Illness;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

PI_NAMEs: MCMAHON, FRANCIS J (contact)

PROJECT_TERMS: 16p11.2;Address;Affect;age group;Agreement;Alternative Splicing;Anterior;Antipsychotic Agents;Astrocytes;atypical antipsychotic;Autopsy;Biological Models;Biology;Bipolar Depression;Bipolar Disorder;Brain;brain cell;brain shape;brain tissue;case control;Catalogs;causal variant;Cause of Death;Cell Differentiation process;cell growth;Cell Line;Cell model;cell motility;Cell Nucleus;Cell Reprogramming;cell type;Cells;Cellular Stress;Cessation of life;Chromosomes;Chronic;cingulate cortex;Collection;Copy Number Polymorphism;Data;deep sequencing;Defect;Development;Diagnosis;differential expression;disability;Disease;DNA;DNA Sequence Alteration;Drug Exposure;Drug usage;Electrophysiology (science);Energy Metabolism;Energy Metabolism Pathway;Exhibits;Exposure to;Family;functional genomics;Gene Expression;Gene Expression Profile;Gene Expression Profiling;Gene Expression Regulation;gene network;Genes;Genetic;Genetic Markers;Genetic Risk;genetic risk factor;genetic variant;Genome;genome editing;genome wide association study;Genomics;Goals;Harvest;Heritability;high risk;Human;Impairment;improved;In Vitro;Individual;induced pluripotent stem cell;Induced pluripotent stem cell derived human neuron;Induced pluripotent stem cell derived neurons;Inherited;Interneurons;Life;Link;Lithium;Macaca;Maintenance;Major Depressive Disorder;Major Mental Illness;Measures;Medicine;Mental disorders;Methods;microscopic imaging;Modeling;Molecular;Mood stabilizers;Morphology;Neurobiology;Neuroglia;Neuronal Dysfunction;neuronal growth;Neurons;neuropsychiatry;notch protein;novel therapeutics;Occupational;Participant;Pathway Analysis;Pathway interactions;Patients;Pattern;Persons;Pharmaceutical Preparations;Play;Prefrontal Cortex;Proliferating;Public Health;Recreation;Resolution;Resources;Risk;Risk Factors;risk variant;RNA;Role;Sampling;Schizophrenia;schizophrenia risk;screening;severe mental illness;Signal Transduction;social;Source;Stress;Structure;Suicide;Synapses;synaptic function;Techniques;Testing;Therapeutic Agents;Time;Tissue-Specific Gene Expression;Tissues;tool;Transcript;transcriptome;transcriptome sequencing;transcriptomics;Valproic Acid;Variant

PROJECT_TITLE: Functional Genomics of Bipolar Disorder


NIH_SPENDING_CATS: Eye Disease and Disorders of Vision;Mental Health;Neurosciences

PI_NAMEs: LEOPOLD, DAVID A (contact)

PROJECT_TERMS: 3-Dimensional;Affect;Animals;Area;Behavior;Brain;brain pathway;Characteristics;Cognition;Complex;Development;Dimensions;Disease;Electrophysiology (science);Environment;Evaluation;Event;experience;experimental study;Eye;Face;Failure;Familiarity;Feeling;Functional Magnetic Resonance Imaging;gene therapy;Geometry;Hand;Human;Image;Individual;Injury;insight;Investigation;Laboratories;Learning;Leber's amaurosis;Life Experience;Methods;movie;Nature;Neurologic;neuromechanism;Neurons;operation;Pathway interactions;Patients;Pattern;phenomenological models;Process;programs;Psychologist;Publishing;rehabilitation strategy;remote monitoring;Research;Research Personnel;Residual state;response;Retina;Retinal Degeneration;Retinal gene therapy;retinotectal;Shapes;Signal Transduction;social;Social Interaction;Stimulus;stimulus processing;Structure;Temporal Lobe;Time;tool;Veins;virtual reality environment;Vision;Visual;visual cognition;Visual Pathways;Visual Perception;visual stimulus;Work

PROJECT_TITLE: Neural Mechanisms of Natural Visual Perception


NIH_SPENDING_CATS: Behavioral and Social Science;Bipolar Disorder;Brain Disorders;Clinical Research;Depression;Genetic Testing;Genetics;Human Genome;Mental Health;Mental Illness;Neurosciences;Prevention;Serious Mental Illness;Suicide

PROJECT_TERMS: Address;age group;Amish;anti-epileptic agents;Antipsychotic Agents;Anxiety;Anxiety Disorders;Attention deficit hyperactivity disorder;autism spectrum disorder;Biology;Bipolar Disorder;Blood Cells;Blood specimen;Brain;Brazil;Calcium Channel Blockers;Calcium ion;Canada;Catalogs;Cause of Death;cell repository;Cessation of life;Clinical;clinical diagnosis;Cognition;Cognitive deficits;cognitive testing;Cohort Studies;Collaborations;Collection;Communities;comorbidity;Copy Number Polymorphism;Data;de novo mutation;depressive symptoms;Diagnosis;Diagnostic;Dimensions;disability;Disease;DNA;DNA Repository;Enrollment;exome;exome sequencing;Family;follow-up;Functional disorder;functional genomics;Future;gene function;gene interaction;Genes;Genetic;genetic association;Genetic Counseling;Genetic Determinism;genetic disorder diagnosis;genetic information;Genetic Risk;genetic risk factor;genetic testing;genetic variant;Genetic Variation;genome sequencing;genome wide association study;genome-wide;Hearing;Heritability;high risk;Immunity;immunoregulation;Impairment;improved outcome;Individual;Individual Differences;induced pluripotent stem cell;Inherited;Ion Transport;Lead;Learning;Life;Lithium;Major Depressive Disorder;Measures;Mennonite;Mental Depression;Mental disorders;Methods;Modeling;Mood Disorders;mood symptom;Moods;Mutation;National Institute of Allergy and Infectious Disease;nervous system development;neurodevelopment;neurogenesis;neuropsychiatry;Neurotic Disorders;novel;novel therapeutics;Occupational;offspring;Parents;Participant;Pathway Analysis;Patients;Persons;Phenotype;Play;polygenic risk score;Population;postsynaptic;Prevention;Process;psychiatric genomics;Publishing;Questionnaires;rare variant;Recording of previous events;Recurrence;Resources;response;Risk;Risk Factors;Risk Taking;risk variant;Role;Sampling;Schizophrenia;schizophrenia risk;severe mental illness;Skin;Sleeplessness;Smoking;SNP array;social;social stigma;Source;Special Population;suicidal risk;Suicide;Suicide attempt;Testing;treatment response

PROJECT_TITLE: Identification of Genes Involved in Major Mood Disorders


NIH_SPENDING_CATS: Behavioral and Social Science;Brain Disorders;Depression;Genetics;Human Genome;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Precision Medicine;Serious Mental Illness;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Human

PROJECT_TERMS: Adverse effects;Adverse event;Aftercare;Alleles;anti-depressive agents;antidepressant effect;Anxiety;Attention;Biological;Biological Assay;Biological Factors;Brain;Candidate Disease Gene;career;cell growth;cell growth regulation;cellular development;Cellular Morphology;clinical center;Code;Collaborations;confocal imaging;cost;Data;database of Genotypes and Phenotypes;Dendritic Spines;Disease remission;Dose;effective therapy;Electrodes;Electrophysiology (science);exome;exome sequencing;experimental study;Family Study;Funding;Future;GABA Receptor;Gene Expression;Genes;Genetic;Genetic Determinism;Genetic Markers;genetic testing;genetic variant;Genome;genome wide association study;genome-wide;Genomics;Glutamate Receptor;Goals;Heritability;High-Throughput Nucleotide Sequencing;Human;human induced pluripotent stem cells;improved;In Vitro;individual variation;Induced pluripotent stem cell derived human neuron;insight;Ketamine;Learning;Length;Lithium;Major Depressive Disorder;Measures;Mental Depression;Meta-Analysis;Methods;Morbidity - disease rate;Morphology;mortality;Mus;National Heart, Lung, and Blood Institute;Neurites;Neurons;novel;Outcome;Outcome Study;Pathway interactions;Patients;personalized approach;Persons;Pharmaceutical Preparations;programs;psilocin;Psilocybin;Recovery;Resistance;response;Risk;Sampling;Series;side effect;Signal Pathway;Signal Transduction;social factors;stem cells;Symptoms;Synapses;synaptogenesis;Testing;therapy resistant;Time;Treatment outcome;treatment response;treatment-resistant depression;Twin Studies;United States National Institutes of Health;Variant;Withdrawal;Work

PROJECT_TITLE: Genetic Determinants of Antidepressant Response


NIH_SPENDING_CATS: Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Depression;Mental Health;Neurosciences;Sleep Research

PROJECT_TERMS: ABCG2 gene;Age;alertness;Amyloid;Amyloid Proteins;Animals;Annual Reports;anti-depressive agents;Astrocytes;Binding;Binding Sites;Biological Markers;Blood specimen;Brain;Brain region;Cells;Characteristics;Chemicals;Chemistry;Chronic;Clinical Research;cognitive performance;Collaborations;Cyclic AMP;cyclooxygenase 1;cyclooxygenase 2;density;Development;Diagnostic;Disease;Dose;Electroencephalography;Enrollment;Exhibits;experience;Female;first-in-human;Functional disorder;Future;General Population;Glycoproteins;Goals;healthy volunteer;Hippocampus;Hour;Human;Human Volunteers;Image;In Vitro;in vivo imaging;indexing;Individual;Inflammation;Inflammatory;inhibitor;intravenous injection;Ketoprofen;Knockout Mice;Label;Laboratories;Literature;Magnetic Resonance Imaging;male;Measures;Microglia;Military Personnel;Mitochondrial Proteins;Modeling;Monkeys;neuroimaging;neuroinflammation;neuropsychiatric disorder;nonhuman primate;novel;Occipital lobe;Oral Administration;overexpression;Parents;Participant;Patients;Pattern;PDE4B;Peripheral;Permeability;Phagocytosis;Pharmaceutical Preparations;phosphodiesterase IV;Physiological Processes;Positron-Emission Tomography;Process;Prostaglandin-Endoperoxide Synthase;Protein Isoforms;Proteins;Protocols documentation;Radioactivity;Radiolabeled;radioligand;radiotracer;Rattus;receptor;Recovery;research clinical testing;Research Institute;Rolipram;Scanning;Second Messenger Systems;Selective Serotonin Reuptake Inhibitor;single episode major depressive disorder;Site;Sleep;Sleep Deprivation;Sum;Synapses;Synaptic Vesicles;System;Techniques;Testing;Thalamic structure;Time;Tissues;tool;Travel;uptake;virtual;volunteer;Work

PROJECT_TITLE: Clinical Evaluation of PET Radiotracers


NIH_SPENDING_CATS: Behavioral and Social Science;Biomedical Imaging;Bipolar Disorder;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Depression;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Serious Mental Illness;Sleep Research;Suicide

PI_NAMEs: ZARATE, CARLOS  (contact)

PROJECT_TERMS: Acute;Affect;Age;AMPA Receptors;Amygdaloid structure;Anhedonia;Anterior;anti-depressive agents;antidepressant effect;Architecture;Arousal;Biochemical;Biological Markers;biomarker identification;Bipolar Depression;Bipolar Disorder;blood-brain barrier crossing;Brain-Derived Neurotrophic Factor;Cell Adhesion;Cell Adhesion Molecules;cellular targeting;Cerebrospinal Fluid;Cessation of life;Chronic;cingulate cortex;Clinical;Corpus striatum structure;Cross-Over Trials;Data;Depressed mood;depressive symptoms;Diagnostic;Disabling;Dorsal;Double-Blind Method;Drug Kinetics;Electroencephalography;Electrophysiology (science);Fatigue;Feeling suicidal;Female;Functional disorder;Functional Magnetic Resonance Imaging;Genetic;Glutamates;Growth Factor;healthy volunteer;Hippocampus;Homeostasis;Hour;Image;Impairment;improved;Individual;Infusion procedures;Insula of Reil;Insulin;interest;Ketamine;Laboratories;Left;Magnetic Resonance Imaging;Magnetoencephalography;Major Depressive Disorder;male;Measures;Mediation;Medical;Mental Depression;metabolomics;MicroRNAs;Molecular Target;Montgomery and Asberg depression rating scale;Mood Disorders;neural correlate;neural network;neurogenesis;Neuronal Plasticity;Neuropsychology;neurotransmission;NMDA receptor antagonist;non rapid eye movement;norketamine;Outcome Measure;Participant;Pathway interactions;Patients;Pattern;Placebo Control;Placebos;Plasma;pleasure;Polysomnography;Prefrontal Cortex;primary outcome;Protein Tyrosine Kinase;Proteins;Proteomics;Protocols documentation;Public Health;Randomized;rapid eye movement;Recurrence;Relapse;Research;response;Rest;Saline;Scanning;secondary analysis;severe mental illness;sex;Sex Differences;Sleep;Sleep disturbances;sleep onset;Slow-Wave Sleep;Spectrum Analysis;standard care;suicidal;suicidal behavior;Symptoms;Synaptic plasticity;synaptogenesis;System;Time;treatment-resistant depression;Work

PROJECT_TITLE: Glutamatergic Modulators for Rapid and Sustained Antidepressant Effect


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Congenital Structural Anomalies;Genetics;Human Genome;Intellectual and Developmental Disabilities (IDD);Mental Health;Neurosciences;Pediatric;Rare Diseases

PROJECT_TERMS: 7q11.23;Absence of pain sensation;Adult;Affect;Age;Age at Menarche;Amygdaloid structure;Anterior;Anxiety;Aorta;Aortic Valve Stenosis;Area;autism spectrum disorder;Behavior;Behavioral;Behavioral Mechanisms;behavioral phenotyping;Bilateral;boys;Brain;Brain region;brain size;Cell Line;Cell Physiology;Cells;Cellular Morphology;Cerebellum;Characteristics;Child;Childhood;Chromosome 7;Clinical;clinical predictors;clinically relevant;Cognition;cognitive function;cohort;Complex;connectome;Copy Number Polymorphism;Data;Data Collection;data resource;Dedications;design;Development;Diffusion Magnetic Resonance Imaging;Disease;DNA;DNA Sequence;dorsal visual stream;Dose;Elastin;emerging adult;Emotional;Equation;experience;experimental study;Face;Face Processing;Fiber;Fright;Functional Magnetic Resonance Imaging;Gene Dosage;Gene Duplication;Gene Mutation;General Population;Genes;Genetic;Genetic Determinism;genome wide association study;genome-wide;Genomic Segment;Genotype;girls;Goals;gray matter;Growth;Handedness;Haploidy;Haplotypes;Heterogeneity;human model;in vivo;indexing;Individual;induced pluripotent stem cell;Insula of Reil;intraparietal sulcus;Judgment;Knowledge;Lead;Life;LIMK1 gene;Link;Literature;Magnetic Resonance Imaging;Measurement;Measures;Methodology;Methods;microdeletion;Modeling;Molecular Abnormality;morphometry;Multimodal Imaging;multimodal neuroimaging;myelination;Nature;neural;neural circuit;Neurobiology;neurodevelopment;neurogenetics;neuroimaging;neuromechanism;Neurons;neuropsychiatric disorder;novel;Pain management;pain sensitivity;Participant;Pathology;Pattern;Personality;Persons;Phenotype;Pituitary Gland;Play;Population Characteristics;Positron-Emission Tomography;pubertal timing;Puberty;rare genetic disorder;Regression Analysis;Regulation;response;Rest;Role;Route;Sampling;Seminal;Series;sex;Shapes;Siblings;Single Nucleotide Polymorphism;SNP array;SNP genotyping;social;Social Behavior;social cognition;social influence;Stimulus;Structure;success;Surface;Syndrome;System;Techniques;Testing;Tissues;transcriptome sequencing;Translating;Variant;Veins;ventral visual stream;Visual;Visuospatial;Williams Syndrome;Work

PROJECT_TITLE: Multimodal Neuroimaging of Gene-Brain Relationships in Williams Syndrome


NIH_SPENDING_CATS: Behavioral and Social Science;Brain Disorders;Clinical Research;Depression;Estrogen;Genetics;Major Depressive Disorder;Maternal Health;Maternal Morbidity and Mortality;Mental Health;Mental Illness;Neurosciences;Serious Mental Illness;Women's Health Research

PROJECT_TERMS: Accounting;Address;Affective;Affective Symptoms;Allopregnanolone;Amygdaloid structure;Anxiety;Appearance;Behavior;Behavioral;behavioral health;behavioral phenotyping;behavioral response;Biological;Body mass index;Brain;Brain region;Breast;burden of illness;cell injury;Cell Line;Cell model;cell type;Cellular Stress;Central Nervous System;Characteristics;Child;Childbirth;Chronic Disease;Classification;Clinical;clinical diagnosis;Clinical Management;Clinical Protocols;Clinical Research;Clinical Trials;cognitive function;Collaborations;comorbidity;comparison control;Data;Data Analyses;Data Set;Depressed mood;depressive symptoms;desensitization;Development;Diagnostic;differential expression;Direct Costs;Disease;Disparity;DNA;DNA Methylation;Down-Regulation;Endocrine;Epidemiology;epidemiology study;Estradiol;Event;Exposure to;Facilities and Administrative Costs;food craving;Free Radicals;Frequencies;Functional disorder;Future;Gene Expression;Genes;Genetic;Genetic Transcription;genomic data;Genomics;Genotype;Glucocorticoids;Glutathione S-Transferase;GSTT1 gene;Health;Heavy Metals;High Risk Woman;Hormonal;Hormone imbalance;Hormone secretion;hormone therapy;Hormone use;Hormones;human induced pluripotent stem cells;Hypothyroidism;In Vitro;in vivo;Infant;Infanticide;innovation;interest;Intervention;Laboratories;life span;lymphoblastoid cell line;Machine Learning;Major Depressive Disorder;Medial;Mediator;member;Menstrual cycle;Menstruation Disturbances;Mental Depression;Mental disorders;metabolome;metabolomics;Methods;Modeling;Molecular;Molecular Target;Mood Disorders;Moods;Morbidity - disease rate;mortality;Mothers;mouse model;multimodal neuroimaging;multiple datasets;National Institute on Alcohol Abuse and Alcoholism;Nature;neural;Neurons;neuroregulation;neurosteroids;novel;novel therapeutics;Ovarian;Pain;Patients;Pattern;Perimenopause;Phenotype;physical symptom;Physiological;polygenic risk score;Postpartum Depression;Postpartum Period;Predisposition;Prefrontal Cortex;Pregnancy;premenstrual dysphoric disorder;Premenstrual syndrome;prevent;Procedures;Process;Progesterone;Proteins;Psychoses;Rare Diseases;Reactive Oxygen Species;Recurrence;Reduced Glutathione;Reporting;reproductive;reproductive hormone;Reproductive Periods;reproductive system disorder;Research;response;Risk;Risk Factors;risk variant;RNA;Role;Sampling;Sex Differences;Signal Transduction;single nucleus RNA-sequencing;Sleep;Source;Specificity;steroid hormone;Steroid Receptors;Steroids;Stimulus;Suicide;Symptoms;System;Techniques;Testing;Transcript;transcriptomics;Transgenic Mice;Variant;Woman;Women's study;Work

PROJECT_TITLE: Reproductive Endocrine Related Mood Disorders-Differential Sensitivity


NIH_SPENDING_CATS: Aging;Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Cerebrovascular;Clinical Research;Contraception/Reproduction;Depression;Estrogen;Genetics;Human Genome;Menopause;Mental Health;Mental Illness;Neurosciences;Stem Cell Research;Stem Cell Research - Induced Pluripotent Stem Cell;Stem Cell Research - Induced Pluripotent Stem Cell - Non-Human;Women's Health Research

PROJECT_TERMS: Acute;Affect;Affective;Agonist;Allopregnanolone;Amygdaloid structure;Animals;Back;Behavior;behavioral response;Biological;Brain;Brain region;Brain-Derived Neurotrophic Factor;C57BL/6 Mouse;Cell Line;cell type;Cells;Central Nervous System;Cerebrovascular Circulation;Child;Cholinergic Receptors;cingulate cortex;Clinical Protocols;Clinical Research;Cognitive;cognitive performance;Collaborations;Companions;Data;density;dentate gyrus;Development;differential expression;differentiation protocol;Dopamine;Dopamine D2 Receptor;Dopamine Receptor;Dose;Electrophysiology (science);Estradiol;Estrus;Evaluation;experience;Exposure to;extracellular vesicles;Functional disorder;Functional Magnetic Resonance Imaging;functional MRI scan;GABA transporter;Gene Expression;Genes;Genetic;genetic variant;Genetic Variation;genomic variation;Genotype;Glutamate Receptor;Goals;Gonadal Steroid Hormones;Gonadotropin Hormone Releasing Hormone;Hippocampus;Hormonal;Hormone Antagonists;hormone sensitivity;Hormones;Human;Hypogonadism;hypothalamic-pituitary-adrenal axis;immunocytochemistry;Individual;induced pluripotent stem cell;Longitudinal Studies;Mass Spectrum Analysis;Measures;Menopause;Menstrual cycle;Mental Depression;methylome;Mood Disorders;Mus;nerve stem cell;Nervous System Physiology;neural;neural circuit;neuroimaging;Neurons;neurophysiology;neuropsychiatry;neurosteroids;Nucleus Accumbens;older women;Oral;Ovarian;Ovarian Ablation;Ovarian hormone;Ovariectomy;Oxygen;Oxytocin Receptor;Patients;Perimenopause;phenomenological models;Physiological;pleiotropism;Positron-Emission Tomography;Prefrontal Cortex;premenstrual dysphoric disorder;Procedures;Process;Progesterone;Protocols documentation;Puberty;Regimen;Regulation;Reporting;response;Rewards;Role;serotonin receptor;Signal Repression;Signal Transduction;Sorting;Steroid Receptors;Steroids;Stress;Symptoms;System;Techniques;Testing;Time;Tissues;trafficking;transcriptome sequencing;Variant;Water;Wisconsin;Withdrawal;Woman;Work;young woman

PROJECT_TITLE: The Neuroregulatory Effects of Gonadal Steroids in Humans


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Brain Disorders;Clinical Research;Mental Health;Mental Illness;Neurosciences;Pediatric

PI_NAMEs: LI, ZHENG  (contact)

PROJECT_TERMS: 3-Dimensional;Address;Adolescent;Adult;Adverse event;Affect;Aggressive behavior;aging brain;Anxiety;Anxiety Disorders;Apical;Attention deficit hyperactivity disorder;autism spectrum disorder;Autophagocytosis;Autophagosome;Behavior;Behavioral;Behavioral Paradigm;Bipolar Disorder;Brain;brain circuitry;Brain region;CASP3 gene;Chemosensitization;Classification;Cognitive;Complement;Computer software;Consumption;Dendrites;Dendritic Spines;density;design;Development;Distal;Dyes;Electrophysiology (science);Emotional;Emotions;Excitatory Synapse;Extinction;FDA approved;Fiji;Filopodia;Foundations;Frustration;Genetic;Goals;Golgi method;Growth;Heterogeneity;Hippocampus;Human;human study;Impaired cognition;Impairment;in vivo;Individual;insight;interest;Intermittent Explosive Disorders;Investigation;Knockout Mice;Label;learned behavior;Learning;life span;Locomotion;Long-Term Depression;Magnetoencephalography;Major Depressive Disorder;Manuals;Maps;Measures;Mediating;Mediator;Memory;Mental Depression;Mental disorders;Methodology;Methods;Microglia;Modeling;Molecular;Morphology;Motivation;Mus;Neck;Nervous System Disorder;neural;neural circuit;neuromechanism;Neurons;novel;Oppositional Defiant Disorder;optogenetics;Output;Participant;Pathology;Physiology;Plug-in;Positioning Attribute;postsynaptic;postsynaptic neurons;presynaptic;Preventive;Process;Property;protein degradation;Proteins;Protocols documentation;Public Health;reconstruction;Regulation;Reproducibility;Research;Research Personnel;Resistance;response;Rewards;Role;Schizophrenia;severe mood dysregulation;Site;Social Behavior;Stains;stem;Structure;Symptoms;Synapses;synaptic function;Synaptic plasticity;Techniques;Technology;Therapeutic;Thinness;Three-dimensional analysis;Time;tool;transmission process;Vertebral column;Visualization;Work;Workload;Youth

PROJECT_TITLE: Molecular Mechanisms of Synapse Development and Plasticity


NIH_SPENDING_CATS: Anxiety Disorders;Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Depression;Mental Health;Mental Illness;Neurosciences;Serious Mental Illness

PROJECT_TERMS: Achievement;Affect;Amygdaloid structure;Animal Testing;Animals;Anterior;Anxiety Disorders;Arousal;Behavior Control;Behavioral;Bilateral;Brain;cingulate cortex;Control Animal;Data;Decision Making;Diameter;Emotional;Emotions;Event;expectation;Feedback;frontal lobe;Functional disorder;Future;Goals;Heart Rate;improved;Laboratories;Lesion;Major Depressive Disorder;Measures;Medial;Mental Depression;Mental disorders;Methods;Mood Disorders;neuromechanism;Neurons;neurophysiology;Neuropsychology;neurotoxic;Obsessive-Compulsive Disorder;Outcome;Panic Attack;Persons;Play;Process;Property;Pupil;Reaction;Regulation;response;reward anticipation;reward expectancy;reward processing;Rewards;Role;Sensory;Signal Transduction;social cognition;Stimulus;Syndrome;theories;Time

PROJECT_TITLE: Neural mechanisms of reward processing and emotion


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Depression;Eye Disease and Disorders of Vision;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences

PROJECT_TERMS: Acetylcholine;Address;Affect;Amines;Amygdaloid structure;Anatomic Border;anatomical tracer;Anatomy;Animal Model;Animals;Anterior;Anxiety;Area;Arousal;aspirate;Attention;autism spectrum disorder;Basal Ganglia;Behavior;behavioral impairment;Bilateral;Bipolar Disorder;Brain;calbindin;Cell Nucleus;Cells;Cercopithecidae;Cerebrovascular Circulation;Choice Behavior;Cholera Toxin Protomer B;cholinergic;Cholinergic Fibers;cingulate cortex;Clinical Research;Cognitive;cognitive testing;Comparative Study;Complex;Corpus striatum structure;Decision Making;Deep Brain Stimulation;density;Dextrans;Disease;Disparity;Dorsal;Electrophysiology (science);emotion regulation;Emotions;esterase;Evolution;Excision;Excitotoxic lesion;Exhibits;Fiber;flexibility;Foundations;frontal lobe;Functional disorder;Genetic;Glutamate Transporter;Goals;Health;Impairment;improved;Inferior;information processing;Injections;Interneurons;Interruption;Intervention;Knowledge;Label;Lateral;Learning;Lesion;Limbic System;Link;Macaca;magnocellular;Major Depressive Disorder;Measures;Medial;Mediating;Mental disorders;Methodology;Methods;Modeling;Molecular;Monkeys;Mood Disorders;Nature;Negative Valence;nerve supply;neural;neuroimaging;Neurons;neurophysiology;Nucleus Basalis Magnocellularis;Obsessive-Compulsive Disorder;Panic Attack;Parvalbumins;parvocellular;Pathway interactions;Patients;Pattern;Phobias;Phylogenetic Analysis;Positioning Attribute;Positive Valence;Prefrontal Cortex;Primates;Process;Pulvinar structure;Quality of life;Rattus;reduce symptoms;Reporting;Research;response;reward processing;Rodent;Role;Schizophrenia;social cognition;Source;Stains;Stimulus;Structure;Structure-Activity Relationship;superior colliculus Corpora quadrigemina;Tarsiidae;Temporal Lobe;Time;Tissue Stains;Tissues;Tracer;Translating;Tupaiidae;Visual;visual information;Visual Pathways;Visual System;Visualization;Work

PROJECT_TITLE: Neural Substrates of Reward Processing and Emotion


NIH_SPENDING_CATS: Assistive Technology;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Biotechnology;Clinical Research;Disability Research;Mental Health;Neurosciences;Rehabilitation

PI_NAMEs: BAKER, CHRIS  (contact)

PROJECT_TERMS: Adult;Age;Amputation;Amputees;Area;arm;behavior measurement;Behavioral;Biomimetics;Bionics;Blindness;Body part;Brain;brain computer interface;Brain imaging;Cognitive;Critical Thinking;Data;design;Development;Devices;Digit structure;Electromyography;experience;Feedback;flexibility;foot;Forearm;Functional disorder;Functional Magnetic Resonance Imaging;Goals;gray matter;Hand;Hand functions;Human;Human body;improved;Injury;insight;Intuition;Learning;life span;Limb Prosthesis;Limb structure;Lip structure;Magnetic Resonance Imaging;Maps;Measures;Motor;Movement;Nature;Nervous System;neural;neuromechanism;novel;Participant;Patients;Performance;Population;preservation;Prosthesis;prosthetic hand;Regimen;Rehabilitation therapy;Research;Robotics;Scanning;Shapes;skills;Source;Stroke;Structure;System;Task Performances;Time;tool;Training;training opportunity;Upper Extremity;Visual;visual tracking;white matter;Work

PROJECT_TITLE: Learning and plasticity in the human brain


PROJECT_TITLE: The Neural Underpinnings of Functional MRI Networks


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Eye Disease and Disorders of Vision;Mental Health;Neurosciences;Pediatric

PROJECT_TERMS: absorption;Adult;Animals;Area;Behavior;Biology;Brain;Brain Diseases;Brain Injuries;Brain Mapping;Businesses;cell cortex;Cells;Cerebral cortex;Characteristics;Childhood;clinical application;combinatorial;Dedications;Development;Electrophysiology (science);experience;Exposure to;extrastriate visual cortex;Face;Facial Expression Recognition;Familiarity;Fluorescence;Functional Imaging;Functional Magnetic Resonance Imaging;Future;gene therapy;Genetic;Goals;Human;imaging modality;Impairment;Individual;Learning;Life;Light;Link;Memory;Mental disorders;Methods;Microelectrodes;Modification;Monitor;Nature;Nervous System Disorder;neural circuit;neurodevelopment;Neuronal Plasticity;Neurons;Neurosciences;novel;operation;Opsin;optical imaging;Physiology;Play;Population;pre-clinical research;preference;Pregnancy;Process;Research;Research Personnel;response;Signal Transduction;skills;social;Social Interaction;Social Perception;Sports;Spouses;Stimulus;System;Temporal Lobe;Time;tool;Traction;transgene expression;Translating;Viral;Vision;Visual;visual information;visual learning;visual processing;Voice;Work

PROJECT_TITLE: Neurodevelopment and Plasticity in Social Neural Circuits


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Clinical Research;Eye Disease and Disorders of Vision;Mental Health;Neurosciences

PROJECT_TERMS: Affect;American;Apple;Area;autism spectrum disorder;Behavior;Behavioral;behavioral response;Body part;Brain;Brain imaging;Brain region;Categories;Cephalic;cognitive process;Complex;Computer Models;computer science;crowdsourcing;Data;Databases;Dimensions;Electric Stimulation;Elements;English Language;Episodic memory;experience;experimental study;Eye;Eye Movements;Face;Face Processing;falls;Food;foot;Functional Magnetic Resonance Imaging;Goals;Grain;grasp;Hand;Human;Image;Individual;insight;interest;Knowledge;large-scale database;Learning;Leg;Light;Link;Magnetic Resonance Imaging;Magnetoencephalography;Measures;Medial;Memory;Mental Health;mental representation;Modeling;Nature;Nervous System Disorder;neural;Neurosciences;novel;object recognition;Parietal;Participant;Perception;Persons;Psychology;Research;Resources;response;Retina;Role;Running;Sampling;Shapes;skills;Social Behavior;Stimulus;Stroke;Tennis;Testing;tool;Transcranial magnetic stimulation;Visual;Visual Cortex;Visual Perception;Work

PROJECT_TITLE: Object, face,  body and scene representations in the human brain


NIH_SPENDING_CATS: Autism;Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Intellectual and Developmental Disabilities (IDD);Mental Health;Neurosciences;Pediatric

PI_NAMEs: MARTIN, ALEX  (contact)

PROJECT_TERMS: Affect;autism spectrum disorder;autism symptoms;Autobiography;base;Behavior;Behavioral;Brain imaging;Cerebral hemisphere;Characteristics;Clinical;Cognition;cognitive neuroscience;Communication;Communication difficulty;developmental disease;Event;Exhibits;experience;flexibility;Functional Magnetic Resonance Imaging;Goals;imaging study;Individual;individuals with autism spectrum disorder;instrument;interest;Intuition;Journals;Left;Life;Literature;Magnetic Resonance Imaging;Magnetoencephalography;Measures;Memory;Memory impairment;neural;neural circuit;neural correlate;neuroimaging;Neuropsychological Tests;Neuropsychology;Neurosciences;Participant;Pervasive Development Disorder;Play;Process;Protocols documentation;Publishing;Questionnaires;Reporting;Research;Role;skills;social;social cognition;social communication;Speech;Technology;visual tracking;way finding;Work

PROJECT_TITLE: The Cognitive Neuroscience of Autism Spectrum Disorders


NIH_SPENDING_CATS: Acquired Cognitive Impairment;American Indian or Alaska Native;Behavioral and Social Science;Biodefense and Related Countermeasures;Brain Disorders;Childhood Injury;Clinical Research;Clinical Trials and Supportive Activities;Coronaviruses;Coronaviruses Disparities and At-Risk Populations;Emerging Infectious Diseases;HIV/AIDS;Health Disparities and Racial or Ethnic Minority Health Research;Health Services;Immunization;Infectious Diseases;Mental Health;Mental Illness;Neurosciences;Pediatric;Post-Acute Sequelae of SARS-CoV-2 infection (PASC) including Long COVID;Prevention;Racial and Ethnic Minority Health Research;Social Determinants of Health;Suicide;Suicide Prevention;Vaccine Related

PI_NAMEs: PAO, MARYLAND  (contact)

PROJECT_TERMS: Address;Adult;Age;Alaska Native;Allergic Reaction;Ambulatory Care Facilities;American Indians;Anxiety;Area;Argentina;Argentine;Arterial Disorder;Attention;Autoimmune;autosome;Awareness;Behavioral;behavioral phenotyping;Black race;Brain Diseases;Brain Neoplasms;Catatonia;Cerebrum;Childhood;Chronic;Chronic Fatigue Syndrome;Clinical;clinical care;clinical center;Clinical Pathways;Clinical Research;clinical training;Clinical Trials;Clinics and Hospitals;Cognitive;cognitive function;Collaborations;Communicable Diseases;Communities;Consult;Consultations;Convalescence;coping;COVID-19;COVID-19 pandemic;COVID-19 pandemic effects;COVID-19 sequelae;COVID-19 survivors;COVID-19 vaccine;Data Analyses;Data Set;data submission;Delirium;design;Disease;Disparity;Distress;Documentation;Dose;Educational workshop;Electronics;Emotional;emotional functioning;Encephalitis;Enrollment;Environmental Impact;environmental stressor;Epilepsy;Ethiopia;Evaluation;experience;Extramural Activities;Faculty;Family;Fatigue;Follow-Up Studies;Gender;Genetic;Health;Health Status;healthy volunteer;high risk;HIV;HIV/AIDS;Hypersensitivity;Immune System Diseases;Inflammatory;interdisciplinary approach;International;Intramural Research Program;irradiation;Knowledge;Language;Lead;life span;Longitudinal Studies;Measurement;Measures;Medical;Mental disorders;Mental Health;Mission;Monitor;multidisciplinary;N-Methyl-D-Aspartate Receptors;National Institute of Allergy and Infectious Disease;National Institute of Child Health and Human Development;National Institute of Drug Abuse;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;native youth;Natural History;Neonatal;Nepal;neuroAIDS;neurocognitive disorder;neurodevelopment;Neurodevelopmental Disorder;neuropsychiatry;Neuropsychology;Nevada;NIH Office of AIDS Research;opioid use disorder;outreach;Parkinson Disease;Participant;Pathway interactions;Patient Self-Report;Patients;Pediatric Oncology;pediatric patients;Persian Gulf Syndrome;Persons;Phenotype;physical conditioning;Play;Population;Population Heterogeneity;Portugal;Post-Acute Sequelae of SARS-CoV-2 Infection;Prevention Research;programs;Protocols documentation;Psyche structure;psychiatric comorbidity;Psychiatrist;Psychiatry;psychologic;Psychologist;Psychoses;psychosocial;Public Health;public repository;Publishing;Questionnaires;Race;Rare Diseases;Reaction;recruit;Research;research clinical testing;Research Personnel;research study;Research Subjects;Research Support;Resource-limited setting;Resources;response;Role;safety assessment;SARS-CoV-2 immunity;SARS-CoV-2 infection;screening;Screening procedure;screening program;Services;Site;Sleep;sleep difficulty;social;Social Workers;Spanish;Spirituality;Standardization;Study Subject;Subcortical Infarctions;Subcortical Leukoencephalopathy;Substance abuse problem;suicidal behavior;suicidal risk;Suicide;Suicide prevention;suicide rate;Symptoms;Syndrome;telehealth;Time;tool;tool development;Training;Translating;United States Indian Health Service;United States National Institutes of Health;Vaccines;validation studies;Visit;volunteer;web site;Work;Youth

PROJECT_TITLE: Clinical Research in the NIMH Office of the Clinical Director


NIH_SPENDING_CATS: Behavioral and Social Science;Bipolar Disorder;Brain Disorders;Clinical Research;Clinical Trials and Supportive Activities;Depression;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Obesity;Serious Mental Illness;Suicide

PROJECT_TERMS: Adult;Affect;Age;AMPA Receptors;antagonist;Anterior;anti-depressive agents;antidepressant effect;Behavioral;Biological Markers;biomarker identification;Bipolar Disorder;Body mass index;Brain imaging;Cessation of life;cingulate cortex;Clinical;Clinical Trials;Cognitive;collected works;comorbidity;computerized;Controlled Clinical Trials;Data;depressive symptoms;design;Diagnosis;Dimensions;Disease;Dissociation;Dorsal;Double-Blind Method;efficacy evaluation;Electrophysiology (science);Enrollment;experience;Feeling hopeless;Feeling suicidal;Female;follow up assessment;Frequencies;Functional disorder;Future;Genes;Genetic;Hallucinations;healthy volunteer;high body mass index;High Prevalence;high risk;high risk population;hospitalization rates;improved;indexing;Individual;inpatient psychiatric treatment;Insula of Reil;Intervention;Intrinsic drive;Investigation;Investigational Therapies;Ketamine;Lassitude;Left;Life;Link;Literature;Longterm Follow-up;Magnetoencephalography;Major Depressive Disorder;male;Measures;Mediating;Medical;Mental Depression;metabotropic glutamate receptor 2;minimal risk;Montgomery and Asberg depression rating scale;Mood Disorders;mood symptom;National Institute of Mental Health;neural correlate;Neurobiology;Neuropsychological Tests;new therapeutic target;novel;novel therapeutics;Obesity;open label;optimism;Oral;Outcome;Outcome Measure;Outpatients;Overweight;Participant;Patient Self-Report;Patients;peripheral blood;Pharmacotherapy;phenomenological models;Phenotype;Pilot Projects;Placebos;Prefrontal Cortex;Prevalence;Protocols documentation;Proxy;Psyche structure;psychiatric comorbidity;Pyramidal Cells;Questionnaires;receptor;Receptor Activation;Recording of previous events;recruit;Reporting;Research;Research Domain Criteria;Rest;Risk;Risk Factors;Sampling;Scanning;Severities;Severity of illness;single episode major depressive disorder;stellate cell;Stratum Granulosum;suicidal;suicidal behavior;suicidal risk;Suicide;Suicide attempt;suicide attempter;suicide rate;symptomatology;Symptoms;Syndrome;System;Therapeutic Agents;Time;transgender;treatment effect;treatment response;treatment-resistant depression;Validation;women patients

PROJECT_TITLE: Neurobiology and Target Validation of Novel Therapeutic Agents in Mood Disorders


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Brain Disorders;Mental Health;Neurosciences

PI_NAMEs: AVERBECK, BRUNO  (contact)

PROJECT_TERMS: addiction;Adolescence;Amygdaloid structure;Animal Model;Animals;Anxiety;Anxiety Disorders;Area;Basal Ganglia;base;Behavior;Behavioral;Brain;Clinical;Code;Cognitive;Computer Models;Conceptions;Corpus striatum structure;cost;Development;Disease;Dopamine;dopamine system;dopaminergic neuron;Dorsal;experience;experimental study;Feeling;Food;Globus Pallidus;Goals;Human;Image;Lead;Learning;Life;Limbic System;Liquid substance;Mental Depression;Mental disorders;Modeling;motivational processes;neural;neurophysiology;Outcome;Pathologic;Pathology;Patients;Pharmacology;Phylogenetic Analysis;Play;Population;Prefrontal Cortex;Prevalence;Primates;Process;programs;Public Health;Punishment;reinforcer;Research;Rewards;Role;Signal Transduction;Societies;Structure;Students;Support System;System;teacher;Thalamic structure;Trauma;Ventral Striatum;Vertebrates;Work

PROJECT_TITLE: Frontal Striatal Systems and Dopamine in Normal and Pathological Behavior


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Brain Disorders;Clinical Research;Contraception/Reproduction;Depression;Estrogen;Genetics;Human Genome;Mental Health;Mental Illness;Neurosciences;Pediatric;Women's Health Research

PI_NAMEs: SCHMIDT, PETER  (contact)

PROJECT_TERMS: 7q11.23;Adolescence;Adolescent;adolescent health;Adrenal Glands;Adrenal hormone preparation;Age;Age at Menarche;age related;Androgens;Anxiety Disorders;Attention;Autopsy;Basic Science;Behavior;behavior measurement;Behavioral;Bilateral;Biochemical;Blood specimen;Body Composition;Body mass index;bone age;Bone Development;boys;Brain;Breast;burden of illness;Cell Line;Cerebellum;Characteristics;Child;Childhood;Clinical Protocols;cohort;Companions;contextual factors;Data;Dehydroepiandrosterone Sulfate;Delayed Puberty;Depressive disorder;Development;developmental disease;disability;Disease;Dorsal;Dose;Dual-Energy X-Ray Absorptiometry;early life stress;Early-life trauma;Elements;Emotional;Emotions;Endocrine;Entire hair of pubis;Environmental Risk Factor;Estradiol;Evaluation;Event;Exhibits;experience;Exposure to;Family;Family history of;Female Adolescents;First Degree Relative;Functional disorder;functional genomics;Functional Magnetic Resonance Imaging;Future;genome wide association study;Genotype;girls;Gonadal Hormones;Gonadal Steroid Hormones;gray matter;Growth;Growth Factor;Gynecology;Hemorrhage;Hippocampus;Hormones;Human;hypothalamic pituitary gonadal axis;Incidence;indexing;Individual;Interview;Left;Link;Lymphocyte;Magnetic Resonance Imaging;Manuscripts;Maps;Measures;Medical;Menarche;Mental Depression;Mental disorders;Metabolic;methylome;Modeling;Mood Disorders;Moods;Morphology;multimodal neuroimaging;neural;neural network;Neurobiology;neurodevelopment;Neuronal Plasticity;neuroprotection;neuropsychiatric disorder;Neurotransmitters;Outcome Measure;Ovarian;Participant;Pathology;Pattern;peer;Peripheral;Physiological;Pituitary Gland;pituitary gland development;Plasma;Play;Polycystic Ovary Syndrome;Precocious Puberty;Prefrontal Cortex;prepuberty;Prevalence;primary ovarian insufficiency;Process;Production;pubertal timing;Puberty;puberty transition;Radiology Specialty;Reporting;reproductive;Rest;Retinal blind spot;reward anticipation;reward processing;Rewards;Risk;Role;Sampling;Selection Criteria;Serum;Services;Sex Differences;sexual dimorphism;Short-Term Memory;Signal Transduction;Sleep;social;Steroids;Stress;Structure;Structure of supramarginal gyrus;Sulfate;Syndrome;System;Techniques;telomere;Testis;Testosterone;TFF1 gene;Tissues;transcriptome;transcriptome sequencing;United States National Institutes of Health;Variant;virtual;Visceral fat;Visit;white matter;Williams Syndrome;Work

PROJECT_TITLE: Endocrine and Neurobiologic Events Accompanying Puberty


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Biomedical Imaging;Biotechnology;Clinical Research;Genetics;Human Genome;Mental Health;Neurosciences

PI_NAMEs: RAZNAHAN, ARMIN  (contact)

PROJECT_TERMS: Address;Affect;Aneuploidy;Area;Atlases;autism spectrum disorder;Autopsy;Behavior;Behavioral;Biological;Biological Psychiatry;Biology;Brain;Brain imaging;Brain region;Brain scan;Cerebral cortex;Childhood;Chromosome Mapping;Clinical assessments;clinical care;clinical center;Clinical Protocols;Cognition;Cognitive;Collaborations;Complex;computerized tools;Copy Number Polymorphism;cortex mapping;Data;Data Set;Dedications;Detection;Development;Disease;dosage;Ethics;Event;experimental study;falls;Family member;Female;Fingerprint;flexibility;follow-up;Gene Abnormality;Gene Cluster;Gene Dosage;Gene Expression;Gene Expression Profile;General Population;Genes;Genetic Diseases;genetic variant;Genome;Genomics;Goals;Grain;Health;Human;Human Genome;improved;Individual;individuals with autism spectrum disorder;insight;Logistics;male;Maps;Measures;Medical;Mental disorders;Mental Health;Methodology;Methods;Micro Array Data;Modeling;Molecular;mouse model;multi-scale modeling;Mus;Neurobiology;Neurodevelopmental Disorder;neurogenomics;neuroimaging;neuropsychiatric disorder;Outcome;Participant;Pathway interactions;Phenotype;Phenotypic Sex;Population;Prevalence;Property;Protocols documentation;Psychiatry;Publishing;rare genetic disorder;Research;Research Personnel;resilience;Resources;Risk;risk variant;Sampling;sex;Sex Bias;sex chromosome aneuploidy;Sex Chromosomes;Sex Differences;Structure;Syndrome;System;Testing;Thick;tool;Transgenic Mice;translational study;United States National Institutes of Health;Universities;Variant;Vertebral column;Work;X Chromosome;Y Chromosome

PROJECT_TITLE: Section on Developmental Neurogenomics


PI_NAMEs: PENZO, MARIO  (contact)

PROJECT_TERMS: Adaptive Behaviors;Address;Animals;Behavior;Behavioral;Biology;Brain;Calcium;Cells;Complex;Decision Making;Disease;Dorsal;Electrophysiology (science);Emotional;experience;follow-up;Future;goal oriented behavior;Goals;Hunger;Hypothalamic structure;Image;insight;Memory;Mental disorders;Molecular;Monitor;motivated behavior;Motivation;mouse genetics;Mus;Nature;neural circuit;neuromechanism;neuronal circuitry;Neurons;Pathway interactions;Population;Prefrontal Cortex;Process;Publishing;PubMed;Research;Role;sensory integration;Shapes;Signal Transduction;Stress;Structure of paraventricular nucleus of thalamus;System;Techniques;Text;Thalamic structure;Therapeutic Intervention;therapeutic target;Ventral Striatum;Work

PROJECT_TITLE: Dissecting the stress circuits of the paraventricular nucleus of the thalamus


PI_NAMEs: CHUDASAMA, YOGITA  (contact)

PROJECT_TERMS: Acute;acute symptom;Address;Adrenergic Agents;Affect;Agonist;Amygdaloid structure;anatomical tracer;Anxiety;Area;Attention;Attention deficit hyperactivity disorder;Basic Science;Behavior;Behavior Control;behavior test;Behavioral;Brain;brain circuitry;Calcium Signaling;Categories;cell type;Cells;Clinical;Cognition;Cognitive;cognitive control;cognitive function;Collection;Complex;Decision Making;Detection;Disinhibition;Dopamine D1 Receptor;Dorsal;emotion regulation;emotional behavior;Emotions;executive function;Fiber;Fluorescent in Situ Hybridization;frontal lobe;Galanin;galanin receptor;GALR1 Galanin Receptor;Glutamates;Goals;Hippocampus;Human;improved;Impulsivity;inattention;Lesion;Mediating;Medicine;Memory impairment;Methods;Minor;Nature;Nervous System Disorder;neural circuit;Neuroanatomy;Neurobehavioral Manifestations;Neurons;Neuropeptides;Neuropharmacology;neuropsychiatric disorder;neurotransmission;Neurotransmitters;noradrenergic;Norepinephrine;optogenetics;Pathway interactions;Patients;Pattern;Performance;pharmacologic;Pharmacology;Photometry;Play;Population;Prefrontal Cortex;premature;programs;promoter;Prosencephalon;psychosocial;Quality of life;Rattus;receptor;Recombinants;reduce symptoms;Research;response;Rewards;Risk;Risk Behaviors;Risk Taking;Role;selective attention;Shapes;Signal Transduction;Site;skills;social;Social Behavior;spatial memory;Stimulant;Stimulus;Stress;Structure;Synapses;Temporal Lobe;Thalamic Nuclei;Thalamic structure;Time;Ventral Striatum;Virus;Work

PROJECT_TITLE: Neural Circuits Underlying the Control of Executive and Emotional Behavior


NIH_SPENDING_CATS: American Indian or Alaska Native;Behavioral and Social Science;Brain Disorders;Burden of Illness;Cardiovascular;Childhood Injury;Clinical Research;Depression;Health Disparities and Racial or Ethnic Minority Health Research;Mental Health;Mental Illness;Pediatric;Prevention;Psychosis;Racial and Ethnic Minority Health Research;Serious Mental Illness;Substance Misuse;Suicide;Tobacco;Tobacco Smoke and Health;Violence Research;Youth Violence

PROJECT_TERMS: addiction;Adolescent;Adult;adverse outcome;Age;age group;Alaska Native;Alcohols;American Indians;Anxiety;Asian population;Attention;Australia;Bayesian Network;Behavior;Behavioral;Benefits and Risks;Biochemical;Black race;Brain;Brazil;burden of illness;California;Canada;Cardiovascular Diseases;cardiovascular risk factor;Child;child depression;Childhood;climate change;Clinical;Code;Cohort Studies;Collaborations;Communication;Community Health;comorbidity;compare effectiveness;Complement;Consult;convict;COVID-19 pandemic;COVID-19 pandemic effects;cyberbullying;Data;Data Analyses;data resource;Data Sources;design;Development;developmental genetics;Diagnostic;disability burden;Disease;disease classification;early onset;Electronic cigarette;Emotional;epidemiologic data;Epidemiology;epidemiology study;Ethnic Origin;Etiology;evidence base;Exposure to;Family;Family Study;Feeling suicidal;follow-up;Future;Genetic;genetic epidemiology;Goals;Health;health assessment;Health behavior;Health Surveys;high risk;Hispanic Populations;Impairment;improved;Incidence;Individual;Internet;Intervention;Interview;Investigation;Life;Longitudinal Studies;Manic;Maps;Mental Depression;Mental disorders;Mental Health;Mental Health Services;Methods;Mind;Monitor;Mood Disorders;Moods;Music;musician;National Institute of Mental Health;Native-Born;New York;non-affective psychoses;novel;Occupational;Outcome;Parents;Participant;Pattern;pediatric department;Pennsylvania;Perception;Persons;Philadelphia;Physical activity;physical conditioning;Physiological;Population Assessment of Tobacco and Health;population based;Population Heterogeneity;Population Research;Population Study;Predisposition;Prevalence;Prevention;Primary Care;programs;prospective;Prospective Studies;Psyche structure;psychiatric comorbidity;Psychotic Disorders;Public Health;Publications;Publishing;Race;Research;Research Personnel;research study;Resources;Retrospective cohort study;Risk;Risk Factors;Sampling;School Drop-Outs;Self-Injurious Behavior;Sleep;social;Source;Structure;Student Dropouts;Substance Addiction;substance use;Substance Use Disorder;suicidal;Suicide;Surveys;Switzerland;Symptoms;System;systematic review;Thinking;Time;Tobacco use;Universities;Work;years lived with disability;young adult;Youth

PROJECT_TITLE: Population-Based Epidemiologic Research


NIH_SPENDING_CATS: Behavioral and Social Science;Bioengineering;Bipolar Disorder;Brain Disorders;Climate-Related Exposures and Conditions;Clinical Research;Depression;Genetics;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Pediatric;Physical Activity;Prevention;Serious Mental Illness;Sleep Research;Telehealth

PROJECT_TERMS: Academic Medical Centers;Accelerometer;actigraphy;Address;Adolescent;Adult;Affect;Affective;analytical method;Anxiety;Anxiety Disorders;anxiety spectrum disorders;Applet;assessment application;Attention deficit hyperactivity disorder;Australia;Behavior;Biological;Biometry;Bipolar Disorder;Bipolar I;Brain;brain health;Callithrix;Cardiovascular Diseases;Child;Chinese;circadian;circadian biology;Circadian Dysregulation;Circadian Rhythms;Classification;climate change;climate impact;Clinic;Clinical;cognitive function;cognitive testing;cohort;Cohort Studies;Collaborations;comorbid depression;Data;Data Analyses;Data Collection;data management;data modalities;Databases;Depressive disorder;depressive symptoms;design;Development;Devices;diaries;Disease;Doctor of Philosophy;Eating;Ecological momentary assessment;Electronics;Emotions;executive function;Exercise;Exposure to;Family;Family Study;Future;Genetic;genetic association;genetic risk factor;Genetic study;Goals;Health;health data;Heritability;high risk;Hong Kong;Human;Image;indexing;Individual;individual variation;interest;Intervention Studies;Investigation;Joints;Learning;Light;Machine Learning;Major Depressive Disorder;Measures;Memory;Mental Depression;Mental disorders;Mental Health;Methodology;Methods;mHealth;Mind;mobile application;Modeling;Monitor;Monkeys;Mood Disorders;Moods;Motor;Motor Activity;multimodal data;multimodal neuroimaging;multimodality;National Institute of Mental Health;Netherlands;nonhuman primate;novel;offspring;online intervention;Paper;Parents;Participant;Perception;Periodicity;Phase;Phenotype;Philadelphia;Physical activity;physical conditioning;physical inactivity;Population;Population Research;Prevention;Procedures;Process;programs;Protocols documentation;Public Health;Public Health Schools;Publishing;Queensland;Recording of previous events;Reporting;Research;Research Activity;Research Institute;Research Personnel;Role;Sample Size;Sampling;sedentary lifestyle;Site;Sleep;sleep pattern;smartphone based assessment;social deficits;Standardization;Statistical Methods;Structure;Subgroup;substance use;Switzerland;Symptoms;System;Technology;Temperature;Testing;Time;trait;translational study;Twin Multiple Birth;Twin Studies;United States National Institutes of Health;Universities;Work;Wrist;Youth

PROJECT_TITLE: Motor Activity Research Consortium for Health (mMarch)


NIH_SPENDING_CATS: Behavioral and Social Science;Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Depression;Major Depressive Disorder;Mental Health;Mental Illness;Neurosciences;Pediatric;Precision Medicine;Rehabilitation;Serious Mental Illness

PI_NAMEs: LISANBY, SARAH  (contact)

PROJECT_TERMS: 15 year old;Acute;Address;adolescent with autism spectrum disorder;Affect;Age;anti-depressive agents;Anxiety;auditory processing;autism spectrum disorder;Automobile Driving;Award;Behavior;Behavioral;Biological Markers;biomarker discovery;blood-based biomarker;Brain;brain behavior;brain control;Brain region;Cephalic;Cessation of life;Clinical;clinical heterogeneity;Clinical Protocols;Cognitive;cognitive enhancement;Cognitive Therapy;Collaborations;Compulsive Behavior;Data;Development;Devices;diagnostic strategy;Dimensions;disability;Dose;Double-Blind Method;effective intervention;effective therapy;electric field;Electric Stimulation Therapy;Electroconvulsive Therapy;Electroencephalography;endophenotype;Feasibility Studies;Fellowship;Functional disorder;Functional Magnetic Resonance Imaging;General Population;Goals;healthy volunteer;image guided;Impairment;improved;Impulsivity;Individual;inter-individual variation;Intramural Research Program;Ketamine;Learning;Link;Magnetoencephalography;Measures;Memory Loss;Mental Depression;Mentors;Migraine;millisecond;Modeling;Motor Cortex;neurochemistry;Neurocognitive;neurofeedback;neuroimaging;Neuronal Plasticity;neuroregulation;noninvasive brain stimulation;novel;Obsessive-Compulsive Disorder;Outcome;patient stratification;Patients;Performance;personalized approach;personalized intervention;Phase;Population;Protocols documentation;Public Health;Randomized;Research;response;Role;Safety;Sampling;secondary outcome;Seizures;Selection for Treatments;side effect;signal processing;single episode major depressive disorder;smoking addiction;Source;suicidal;Symptoms;Task Performances;Techniques;Testing;Therapeutic;Time;Transcranial magnetic stimulation;transmission process;Treatment Efficacy;treatment-resistant depression;United States National Institutes of Health;Universities;Work;Youth

PROJECT_TITLE: Non-invasive Neuromodulation Unit (NNU)


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Eye Disease and Disorders of Vision;Machine Learning and Artificial Intelligence;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: HISTED, MARK  (contact)

PROJECT_TERMS: Adult;Animals;Area;area striata;Artificial Intelligence;Back;Behavior;Behavioral;Behavioral Assay;behavioral response;Biological;Biological Assay;Brain;calcium indicator;Cells;Cerebral cortex;Code;Cognition;Complex;Data;Decision Making;Dependovirus;design;Detection;Development;Dimensions;Esthesia;experience;Fire - disasters;Genes;Genetic;Hearing;Holography;Image;improved;in vivo;insight;Learning;learning network;Life;Link;Machine Learning;Measures;Methods;Modeling;movie;multi-photon;Mus;neural;neural circuit;neural patterning;neuronal cell body;neuronal patterning;Neurons;novel;operation;Opsin;Optics;optogenetics;Organism;Output;Pattern;Performance;Photic Stimulation;Play;Population;Process;programs;Property;Psychophysics;Recurrence;recurrent neural network;Resolution;response;Role;Sensory;sensory cortex;sensory stimulus;Shapes;speech processing;statistics;Structure;Synapses;System;Time;tool;Training;two-photon;Virus;Vision;Visual;Visual Cortex;Weight;Work

PROJECT_TITLE: Patterns of neuronal activity underlying behavioral decisions


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Eye Disease and Disorders of Vision;Machine Learning and Artificial Intelligence;Mental Health;Neurosciences

PI_NAMEs: AFRAZ, ARASH  (contact)

PROJECT_TERMS: Area;Artificial Intelligence;Behavior;Brain;Communication;electrical microstimulation;Event;extrastriate visual cortex;Eye Movements;Face;Goals;Inferior;Link;Measures;Microinjections;Nature;neural;Neurons;novel strategies;object recognition;optogenetics;Paper;Pharmaceutical Preparations;Primates;Psychophysics;Publishing;Stream;Technology;Temporal Lobe;United States National Academy of Sciences;Visual;Visual Perception;visual processing

PROJECT_TITLE: Unit on Neurons, Circuits and Behavior


NIH_SPENDING_CATS: Brain Disorders;Intellectual and Developmental Disabilities (IDD);Mental Health;Neurosciences

PI_NAMEs: LEE, SOOHYUN  (contact)

PROJECT_TERMS: Address;Adult;Anatomy;Area;autism spectrum disorder;Behavioral;Brain;cell type;Cells;Characteristics;Communication;Dendrites;Development;Developmental Process;Disinhibition;Elements;excitatory neuron;Feedback;gamma-Aminobutyric Acid;Glutamates;Goals;Heterogeneity;high risk;hippocampal pyramidal neuron;Impairment;in vivo calcium imaging;Individual;Intellectual functioning disability;Interneurons;Lead;Link;Maps;Mediating;Motor Cortex;Movement;Mutation;Neocortex;neural;neural circuit;Neurons;Neuropharmacology;neuroregulation;optogenetics;Pattern;Perception;pharmacologic;Population;postsynaptic;presynaptic;Process;programs;Proteins;recruit;Research;risk variant;Role;scaffold;Schizophrenia;selective attention;Sensory;sensory cortex;sensory feedback;Somatosensory Cortex;Somatostatin;Specificity;Synapses;Synaptic Transmission;SYNGAP1;Thalamic Nuclei;Thalamic structure;Time;tool;Transgenic Mice;transmission process;Vasoactive Intestinal Peptide;Work

PROJECT_TITLE: Circuit mechanisms underlying cortical communications


NIH_SPENDING_CATS: Behavioral and Social Science;Clinical Research;Mental Health;Neurosciences;Pediatric;Sleep Research

PI_NAMEs: BUCKLEY, ASHURA  (contact)

PROJECT_TERMS: Adult;Apnea;Archives;arm;autism spectrum disorder;autistic children;Behavior assessment;Behavioral;behavioral health;behavioral phenotyping;Biological Markers;biomarker discovery;Biomedical Engineering;Brain;brain based;Child;Childhood;Chronic;Chronic Disease;Clinical assessments;clinical center;clinical diagnosis;cohort;Collaborations;Collection;Consensus;Consultations;Data;Data Collection;Deposition;Development;Developmental Delay Disorders;Devices;Diagnosis;Discipline;Disease;Educational workshop;Electrophysiology (science);Enrollment;Evaluation;Event;Goals;Home;Hospitals;Individual;Joints;Knowledge;Link;Mediating;Medical;medical specialties;meetings;Mental disorders;Mission;National Heart, Lung, and Blood Institute;National Institute of Biomedical Imaging and Bioengineering;National Institute of Child Health and Human Development;National Institute of Mental Health;National Institute of Neurological Disorders and Stroke;neurodevelopment;Neurodevelopmental Disorder;Neurologist;neurophysiology;neuropsychiatric disorder;neuropsychiatry;novel therapeutic intervention;Obstructive Sleep Apnea;Patients;Pattern;Pediatric cohort;pediatric patients;Persons;Phenotype;Physiological;point-of-care diagnostics;Polysomnography;post SARS-CoV-2 infection;predictive marker;Predisposition;prospective;Protocols documentation;Psychiatrist;Psychologist;public database;Publishing;Pulmonology;recruit;repository;Research;Research Personnel;response biomarker;Risk;Scientist;Services;Signal Transduction;Sleep;Sleep Disorders;sleep pattern;Specialist;Standardization;Therapeutic Intervention;therapeutic target;Translating;Translations;treatment strategy;United States National Institutes of Health;Validation;Woman;Work

PROJECT_TITLE: Sleep and Neurodevelopment Service


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Eye Disease and Disorders of Vision;Mental Health;Neurosciences;Sleep Research

PI_NAMEs: HATTAR, SAMER  (contact)

PROJECT_TERMS: Affect;Animals;Area;Behavior;Behavioral Assay;Biological Clocks;Brain;Brain region;Cell Physiology;Cells;circadian;circadian pacemaker;Circadian Rhythms;Collaborations;Data;Development;Electrophysiology (science);Environment;Future;ganglion cell;Gene Modified;Genetic;Genetic Techniques;Growth;Health;Human;Image;improved;in vivo;Individual;interest;Label;Learning;Life;Light;light effects;Major Depressive Disorder;Manuscripts;Measures;Mediating;medical schools;Memory;Metabolism;Modernization;Molecular;mood regulation;Moods;Morphology;mouse model;Mus;Nature;neural circuit;Neurosciences;novel;Pathway interactions;Personal Satisfaction;Photoreceptors;Phototherapy;Placebo Effect;Population;Primates;Process;Publications;Publishing;Pupil light reflex;receptor;Regulation;Research;Research Project Grants;Rest;Retina;Retinal Ganglion Cells;Role;Signal Transduction;Sleep;Specific qualifier value;Stimulus;Stress;Structure of paraventricular nucleus of thalamus;suprachiasmatic nucleus;System;Thalamic structure;Therapeutic;transcriptome;Universities;Vertebrate Photoreceptors;Virus;Vision;Visual;Work

PROJECT_TITLE: Section on Light and Circadian Rhythms


NIH_SPENDING_CATS: Basic Behavioral and Social Science;Behavioral and Social Science;Bioengineering;Biomedical Imaging;Brain Disorders;Clinical Research;Eye Disease and Disorders of Vision;Mental Health;Mental Illness;Networking and Information Technology R&D (NITRD);Neurosciences

PI_NAMEs: MERRIAM, ELISHA  (contact)

PROJECT_TERMS: area striata;Arousal;Attention;Attention deficit hyperactivity disorder;Auditory;autism spectrum disorder;Brain;Bypass;cerebral hemodynamics;Clinical Protocols;Cognitive;cognitive function;Compensation;Computer Analysis;computer framework;Computer Models;Computer Simulation;computer studies;Confusion;Disease;Emotional;Exhibits;extrastriate visual cortex;Feedback;Frequencies;Functional Magnetic Resonance Imaging;Goals;Health;heart rate variability;Human;imaging study;insight;Laboratories;Lesion;Link;Measurement;Measures;Mental disorders;Modeling;Motion;Motor;multimodality;Mus;Nervous System Disorder;neural;neuromechanism;neuropsychiatric disorder;orientation selectivity;Patients;Perception;Performance;Periodicals;Physiological;Population;Primates;Process;Psychophysics;Publishing;Pupil;receptive field;Research;response;retinotopic;Rewards;Rodent;Role;Schizophrenia;Sensory;Signal Transduction;Stimulus;Stroke;Structure;superior colliculus Corpora quadrigemina;Surface;Testing;Thalamic structure;two-photon;V1 neuron;Visual;Visual Cortex;Visual Perception;visual processing;visual stimulus;Visual System;Work

PROJECT_TITLE: Multiple Scales of Stimulus Representation in the Human Brain


NIH_SPENDING_CATS: Machine Learning and Artificial Intelligence;Mental Health;Networking and Information Technology R&D (NITRD);Neurosciences

PROJECT_TERMS: Affect;Anesthesia procedures;Animals;Area;Artificial Intelligence;Attenuated;attenuation;awake;Behavior;Behavioral;behavioral response;Brain;Brain region;Cells;Cerebral cortex;Cognition;Complex;Data;Expert Systems;Fire - disasters;In Vitro;in vivo;Joints;Machine Learning;Measures;Mus;network models;neural;Neurons;Neurosciences;Optics;optogenetics;Output;Pattern;Process;Property;Recurrence;response;Rest;Sensory;sensory cortex;sensory stimulus;Shapes;Sorting;Sum;Synapses;System;Testing;Theoretical model;Visual;Visual Cortex;Weight;Work

PROJECT_TITLE: Computation by recurrent circuits of the cerebral cortex