[Free radical peroxidation of liver mitochondrial and microsomal phospholipids in rat postnatal development].
Activities of both non-enzymic (ascorbate-dependent) and enzymic NADPH-dependent) peroxidation of microsomal and mitochondrial phospholipids are found to be increased in rat liver during postnatal development. It is suggested, that microsomal NADPH-dependent phospholipid dioxygenase forming a chemical modification of membrane polyenic acyls, can be a factor regulating the activities of membrane-linked enzymes under normal physiological processes.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D005609:Free Radicals; D008099:Liver / Q000254:growth & development; D008566:Membranes / Q000201:enzymology; D008862:Microsomes, Liver / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000378:metabolism*; D009249:NADP / Q000494:pharmacology; D010084:Oxidation-Reduction; D010105:Oxygenases / Q000502:physiology; D010545:Peroxides / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats
D005609:Free Radicals; D010545:Peroxides; D010743:Phospholipids; D009249:NADP; D010105:Oxygenases; D001205:Ascorbic Acid
Svobodnoradikal'noe perekisnoe okislenie mitokhondrial'nykh i mikrosomal'nykh fosfolipidov pecheni v protsesse postnatal'nogo razvitiia krys.