Narcotic cueing properties of intraventricularly administered sufentanil, fentanyl, morphine and met-enkephalin.
The narcotic cueing activity of sufentanil, fentanyl, morphine and met-enkephalin was studied upon their injection into the lateral brain ventricle of the rat. Comparative studies on the analgesic activity of the three narcotics support a close correlation between the narcotic cueing and the analgesic activity of narcotic drugs.
D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000494:pharmacology*; D000813:Anilides / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D003463:Cues; D004305:Dose-Response Relationship, Drug; D004723:Endorphins / Q000494:pharmacology*; D004745:Enkephalins / Q000008:administration & dosage / Q000494:pharmacology*; D005283:Fentanyl / Q000008:administration & dosage / Q000494:pharmacology*; D007276:Injections, Intraventricular; D009020:Morphine / Q000008:administration & dosage / Q000494:pharmacology*; D010880:Piperidines / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
D000701:Analgesics, Opioid; D000813:Anilides; D004723:Endorphins; D004745:Enkephalins; D010880:Piperidines; D009020:Morphine; D005283:Fentanyl