The successful treatment of a case of primary sterility resulting from Fredrickson's Type V hyperlipemia and panhypopituitarism.
Successful treatment of primary sterility in a woman having the rare association of panhypopituitarism with Fredrickson's Type V hyperlipemia is described. Replacement therapy with l-thyroxine, prednisone and a low fat diet cleared the patient's blood of the excessive chylomicrons and very low density lipoproteins. Ovulation was induced with human gonadotrophins, and triplets (two normal girls and a boy) were born.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D002914:Chylomicrons / Q000097:blood; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications*; D007018:Hypopituitarism / Q000150:complications*; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology; D008079:Lipoproteins, VLDL / Q000097:blood; D008596:Menotropins / Q000627:therapeutic use; D014280:Triglycerides / Q000097:blood
D006063:Chorionic Gonadotropin; D002914:Chylomicrons; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D008596:Menotropins