Instability of the bovine MOR-2AB (mitochondrial malate: NAD oxidoreductase) heterodimeric molecule of heterozygous subjects after isoelectric focusing.
The heterodimeric molecule which is characteristic of animals heterozygous for the MOR-2 polymorphism and which is readily seen on enzymograms after electrophoresis is reported to be absent from zymograms performed after isoelectric focusing. A possible explanation is presented based on monomer--dimer equilibrium at pH 8.0--8.5.
D000818:Animals; D002417:Cattle; D004591:Electrophoresis, Polyacrylamide Gel; D006579:Heterozygote; D006863:Hydrogen-Ion Concentration; D007525:Isoelectric Focusing; D008291:Malate Dehydrogenase / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D009132:Muscles / Q000201:enzymology; D011110:Polymorphism, Genetic
D008291:Malate Dehydrogenase