The structure of the flavoenzyme glutathione reductase.
The three-dimensional structure of the dimeric flavoenzyme glutathione reductase from human erythrocytes has been elucidated by an X-ray diffraction analysis at 0.3 nm resolution. The polypeptide chain has been traced, and the binding positions of FAD, NADP and glutathione have been determined. A mechanism for the electron transfer is discussed.
D001665:Binding Sites; D002384:Catalysis; D004912:Erythrocytes / Q000201:enzymology; D005420:Flavoproteins / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D008958:Models, Molecular; D009249:NADP / Q000378:metabolism; D011487:Protein Conformation; D014961:X-Ray Diffraction
D005420:Flavoproteins; D009249:NADP; D005980:Glutathione Reductase