[Proteolytic activities in mature human placenta. II. Neutral peptidases and PZ-peptidase (author's transl)].
Continuing our contributions on proteases of human placenta we enriched some unidentified neutral peptidases by chromatographying freeze dried placenta extracts on CM-Sephadex, followed by preparative isoelectric focusing and chromatography on Ultrogel. By this procedure two Acetyl-aminoacyl-p-nitranilidases, three Ala-Ala-p-nitranilidases, one Benzyloxycarbonyl-Ala-Ala-p-nitranilidase, one Carbobenzoxy-Gly-Pro-Arg-p-nitranilidase and one PZ-peptidase could be characterized in greater detail. Here molecular weights, isoelectric points and pH-optima of these enzymes are reported.
D002845:Chromatography; D002852:Chromatography, Ion Exchange; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007525:Isoelectric Focusing; D007526:Isoelectric Point; D008970:Molecular Weight; D010447:Peptide Hydrolases / Q000032:analysis*; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy
D010447:Peptide Hydrolases
Proteolytische Enzymaktivitäten der reifen menschlichen Plazenta. II. Neutrale Peptidasen und PZ-Peptidase.