Asthma and urticaria during disodium cromoglycate treatment. A case report.
A 10-year-old asthmatic boy began to suffer from urticarial rash and moderately severe bronchospasm after 8 weeks' treatment with disodium cromoglycate. Initially, DSCG had helped to control his asthmatic attacks, and steroid therapy could be discontinued. Inhalation provocation test with DSCG aerosol, 4 months after stopping DSCG treatment, showed an immediate-type 1 response and urticaria. A repeat provocation test, under antihistaminic cover , failed to produce similar response. When DSCG was withdrawn, urticaria vanished and the child remained symptom-free. Disodium cromoglycate is regarded as the possible aetiological agent.
D001249:Asthma / Q000188:drug therapy*; D002648:Child; D004205:Cromolyn Sodium / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012882:Skin Tests; D014581:Urticaria / Q000139:chemically induced*
D006634:Histamine H1 Antagonists; D004205:Cromolyn Sodium