The haemodynamic effects of sodium nitroprusside-induced hypotension during beta-adrenergic blockade and anaesthesia. A case report.
We present the central haemodynamic data obtained during halothane/nitrous oxide anaesthesia in a patient under antihypertensive treatment with propranolol who underwent surgery for intracranial aneurysms in sodium nitroprusside-induced hypotension. Cardiac output remained unchanged when hypotension was induced. Pulmonary capillary wedge pressure decreased. There was a slight increase in heart rate, as well as a minor decrease in stroke volume. Systemic vascular resistance decreased, but pulmonary vascular resistance remained unchanged. The response observed is discussed.
D000319:Adrenergic beta-Antagonists; D000328:Adult; D000769:Anesthesia, Inhalation; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002302:Cardiac Output; D005260:Female; D005292:Ferricyanides; D006221:Halothane; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D007023:Hypotension, Controlled / Q000009:adverse effects; D009599:Nitroprusside; D009609:Nitrous Oxide; D011433:Propranolol / Q000009:adverse effects / Q000627:therapeutic use*; D014655:Vascular Resistance
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D005292:Ferricyanides; D009599:Nitroprusside; D011433:Propranolol; D009609:Nitrous Oxide; D006221:Halothane