Effects of pH on protein binding of lidocaine.
Protein binding of lidocaine (2.5, 5, 10, and 20 microgram/ml in fresh plasma was studied from pH 5.6 to pH 9.8. Percent binding of lidocaine was inversely related to hydrogen-ion and lidocaine concentrations.
D000772:Anesthesia, Local; D001774:Blood Chemical Analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008012:Lidocaine / Q000378:metabolism*; D011485:Protein Binding
D008012:Lidocaine