Flunitrazepam compared with althesin as an induction agent in balanced anaesthesia.
The effects of flunitrazepam and Althesin as anaesthetic induction agents were studied in a double-blind trial in 97 patients undergoing abdominal or gynaecological surgery. There was no difference between the two preparations in respect of the quality of induction. A marked difference in the quality of maintenance of anaesthesia were seen, in favour of flunitrazepam. Recovery was more rapid from Althesin anaesthesia. A low incidence of nausea was observed in both groups.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000530:Alfaxalone Alfadolone Mixture / Q000009:adverse effects / Q000494:pharmacology; D000758:Anesthesia / Q000379:methods*; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005445:Flunitrazepam / Q000009:adverse effects / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011277:Pregnanediones / Q000494:pharmacology
D014151:Anti-Anxiety Agents; D011277:Pregnanediones; D005445:Flunitrazepam; D000530:Alfaxalone Alfadolone Mixture