Selective reactions of nucleobases under biological conditions.
Pentacyanonitrosylferrate/II/ complex reacts under biological conditions (pH= 7.5, T= 25-40 degrees C, dilute solution) selectively with nucleobases. The reaction with adenine and guanine probably leads to nitrosation. A new compound formed in the reaction with adenine is prepared; both this compound and the pentacyanonitrosylferrate/II/ inhibits the multiplication of Escherichia coli.
D000225:Adenine / Q000031:analogs & derivatives / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D003116:Color; D004926:Escherichia coli / Q000187:drug effects; D006147:Guanine; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009603:Nitroso Compounds / Q000494:pharmacology
D009603:Nitroso Compounds; D006147:Guanine; D000225:Adenine