[Mechanisms of changes in the mass of the organs central to immunity during adenovirus carcinogenesis].
The spleen cells transfer from mice CBA at the 25th day of the carcinogenesis latent period induced by adenovirus SA7(S8) to newborn syngeneic animals caused the graft versus host reaction in them. There was splenomegaly and progressive decrease in weight of the recipients' thymus. Analogous alterations of lymphoid organs were noted in the animals infected during the neonatal period by oncogenic adenovirus SA7(C8). Results showed that adenoviral carcinogenesis had some manifestations of autoimmune disease.
D000256:Adenoviridae; D000261:Adenoviruses, Simian; D000818:Animals; D006087:Graft vs Host Reaction; D051379:Mice; D008808:Mice, Inbred CBA; D009374:Neoplasms, Experimental / Q000276:immunology*; D009858:Oncogenic Viruses; D009929:Organ Size; D013154:Spleen / Q000276:immunology* / Q000637:transplantation; D013950:Thymus Gland / Q000276:immunology*; D014185:Transplantation, Isogeneic
O mekhanizmakh izmeneniia massy tsentral'nykh organov immuniteta pri adenovirusnom kantserogeneze.