Protonated polynucleotide structures, 20. Interaction between poly(dG)-poly(dC) and poly(rC).1.
A study of the interaction between poly(dG)-poly(dC) and poly(rC) demonstrates that, at neutral pH and high ionic strength, there is replacement of the dC strand by poly(rC). At acid pH, formation of a triple-stranded complex which equally may involve the replacement phenomenon is observed. There is no evidence for interaction at neutral pH between poly(dG)-poly(dC) and oligo(rC), while a three-stranded complex is formed at acid pH. These data are consistent with the studies of comparative stabilities of double stranded deoxy or ribo polymers and deoxy-ribo hybrids.
D002942:Circular Dichroism; D006863:Hydrogen-Ion Concentration; D009693:Nucleic Acid Hybridization; D009994:Osmolar Concentration; D011066:Poly C; D011068:Poly G; D011089:Polydeoxyribonucleotides; D011131:Polyribonucleotides
D011089:Polydeoxyribonucleotides; D011131:Polyribonucleotides; D011068:Poly G; D011066:Poly C