[Free description of drug effects and description by questionaire of a sleep inducer (flurazepam) by normal test subjects (author's transl)].
Giving flurazepam and placebo to students as subjects, the free description of drug-effects (FD) was compared to the description by a questionaire (QD). The results were: 1. The FD-method was more informative than the QD-method. 2. The FD-method induced less frequent placebo effects and more frequent verum-non-effects than did the QD-method. 3. The results (1) and (2) based mainly on the variables time-to fall-asleep, subjective quality of sleep and total time of sleep, in which variables flurazepam differed significantly from placebo.
D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D004341:Drug Evaluation / Q000379:methods*; D005479:Flurazepam / Q000494:pharmacology*; D006801:Humans; D010919:Placebos; D012890:Sleep / Q000187:drug effects; D013404:Suggestion; D011795:Surveys and Questionnaires
D014151:Anti-Anxiety Agents; D010919:Placebos; D005479:Flurazepam
Freie und gebundene Wirkungsbeschreibung eines Schlafmittels (Flurazepam) durch gesunde Versuchspersonen