[Circulating immune complexes in acute viral hepatitis, chronic active hepatitis, and periarteritis nodosa (author's transl)].
Circulating immune complexes were determined in patients with acute viral hepatitis, chronic active hepatitis and periarteriitis nodosa with the Raji cell technique. Circulating immune complexes were found in 11/18 HBsAg positive and HBsAg negative cases of acute viral hepatitis. In HBsAg positive chronic active hepatitis immune complexes were detectable in 42/43 cases but only in 1/27 HBsAg negative cases. Ten healthy HBsAg carriers demonstrated no detectable immune complexes. Using FITC conjugated antisera against HBs, HBc, and e antigen, immune complexes could not be found in any case of acute viral hepatitis or chronic active hepatitis. Elution of immune complexes from Raji demonstrated IgG, C'3 and a lack of HBsAg, HBc or e antigen. Immune complexes were present in 4/8 cases with periarteriitis nodosa. Viral components were detectable in one case.
D000208:Acute Disease; D000936:Antigen-Antibody Complex; D002908:Chronic Disease; D003176:Complement C3 / Q000032:analysis; D006505:Hepatitis / Q000276:immunology*; D006511:Hepatitis B Antigens / Q000032:analysis; D006525:Hepatitis, Viral, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D010488:Polyarteritis Nodosa / Q000276:immunology*
D000936:Antigen-Antibody Complex; D003176:Complement C3; D006511:Hepatitis B Antigens; D007074:Immunoglobulin G
Zirkulierende Immunkomplexe bei akuter Virushepatitis, chronisch-aktiver Hepatitis und Periarteriitis nodosa.