N-hydroxyamobarbital: the second major metabolite of amobarbital in man.
After oral administration of 14C-labeled amobarbital to healthy subjects, most of the radioactivity was recovered in urine and only 4-5% in feces over a period of 6 days. No unchanged amobarbital was excreted. Two major metabolites were found and isolated. One was 3'-hydroxyamobarbital, which has been previously identified by Maynert. The second could be identified as N-hydroxyamobarbital on the basis of its spectral and chemical properties.
D000654:Amobarbital / Q000032:analysis / Q000378:metabolism* / Q000652:urine; D005243:Feces / Q000032:analysis; D006801:Humans; D006900:Hydroxylation; D008297:Male; D008314:Malonates / Q000032:analysis; D013997:Time Factors; D014508:Urea / Q000032:analysis
D008314:Malonates; D014508:Urea; D000654:Amobarbital