[Effect of acid anions and medium acidity on pH during a change of immunoglobulin G, peculiar to malignant growth, to water-insoluble state].
Affinity of an acid anion for proteins has a decisive effect on conditions for detecting using an acid medium immunoglobulin G peculiar to the malignant growth in blood serum of patients with cancer. Depending on the protein affinity of the anion of the acid used for the reaction immunoglobulin G appearing in blood of patients with cancer under equal conditions may be in a soluble state or change to a sediment. The presence of salts in the reaction mixture has no effect on conditions of the reaction performance. Exposition of blood sera to the acid medium before titration favours a more distinct detection of the studied protein in blood of patients with cancer.
D000818:Animals; D000838:Anions; D000912:Antibodies, Neoplasm / Q000032:analysis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007074:Immunoglobulin G / Q000032:analysis*; D009369:Neoplasms / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000276:immunology; D012995:Solubility
D000838:Anions; D000912:Antibodies, Neoplasm; D007074:Immunoglobulin G
Vpliv anioniv kislot i kislot i kislotnosti seredovishcha na pH perekhodu imunoglobulinu G, kharakternogo dlia zloiakisnogo rostu, v nerozchinnu u vodi formu.