[Resistance against intra- and extracellular bacteria in experimentally aged rats (author's transl)].
The authors study the cellular activity of RES against the microbes intracellular and extracellular parasites in rats with pronounced Progeria-like syndrome of Selye. RES of the experimentally aged animals copes, through with a certain delay, with the invading extracellular bacterium Diplococcus pneumoniae, but is utterly helpless against the intracellular microbe Br. abortus 19. These relations are completly inverted in the rats that have not been experimentally aged.
D000135:Acid Phosphatase / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000375:Aging; D000818:Animals; D001769:Blood / Q000382:microbiology; D001770:Blood Bactericidal Activity; D002003:Brucella abortus / Q000276:immunology; D007114:Immunization; D008099:Liver / Q000276:immunology / Q000382:microbiology; D008168:Lung / Q000276:immunology / Q000382:microbiology; D010586:Phagocytes / Q000201:enzymology; D010587:Phagocytosis; D011371:Progeria / Q000276:immunology; D051381:Rats; D013154:Spleen / Q000276:immunology / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000276:immunology
D000135:Acid Phosphatase; D000251:Adenosine Triphosphatases
Resistenz gegen intra- und extrazelluläre Bakterien bei experimentell gealterten Ratten