[Effects of naloxone on postoperative analgesia].
Two comparable groups of ten patients were studied. After nitrous oxide-oxygen fentanyl-pancuronium anesthesia, half the patients were reversed with a titrated dose of naloxone. Even in titrated doses naloxone rapidly abolished residual post-operative fentanyl analgesia in 80 p. 100 of the patients. In the control group none of the patients complained of pain for an average of six to eight hours. Blood gases in the recovery room were practically the same in reversed and non-reversed patients and were satisfactory.
D000328:Adult; D000368:Aged; D000698:Analgesia; D000697:Central Nervous System Stimulants / Q000037:antagonists & inhibitors; D002986:Clinical Trials as Topic; D005283:Fentanyl / Q000037:antagonists & inhibitors; D006801:Humans; D008297:Male; D008875:Middle Aged; D009022:Morphine Derivatives / Q000037:antagonists & inhibitors; D009270:Naloxone / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000517:prevention & control*; D011182:Postoperative Care; D012119:Respiration / Q000187:drug effects
D000697:Central Nervous System Stimulants; D009022:Morphine Derivatives; D009270:Naloxone; D005283:Fentanyl
Etude des effets de la naloxone sur l'analgésie post-opératoire