Anesthesia for cesarean section III: effects of epidural analgesia on the respiratory adaptation of the newborn in elective cesarean section.
A rise in fetal Paco2 was observed after elective cesarean section in patients anesthetized both with a barbiturate and with nitrous oxide/oxygen. Epidural analgesia seemed to be a good alternative in order to attain better blood gas values in the newborn infant. Fourteen healthy mothers and their infants were studied in connection with elective cesarean section. Epidural analgesia with plain bupivacaine 0.75% was used. Doses varied between 90 and 120 mg. The time between the epidural injection and delivery was around 50 min. In six cases the fetal heart rate was registered continuously. Most of the mothers were sedated with diazepam intravenously or fully anesthetized, after delivery. The mothers were interviewed later. The respiratory adaptation of the infants was studied by blood gas and acid-base measurements in repeated arterial samples during the first 3 hours of life. A comparison was made with a group previously studied, where general anesthesia with a barbiturate, nitrous oxide/oxygen was the method used. The present material showed no differences concerning Pao2 and Paco2 but clearly indicated a tendency towards an earlier normalization of the initial metabolic acidosis. Mothers showed a respiratory alkalosis which was overcompensated by the metabolic component. Maternal blood pressure falls were observed in four cases, and fetal effects could be detected. Although epidural analgesia has a more favorable effect upon the newborn's metabolic component, both the compared methods allow good respiratory adaptation provided they are used correctly. Mothers can be given the opportunity to choose between being conscious or asleep when their child is delivered.
D000222:Adaptation, Physiological; D000767:Anesthesia, Epidural; D001794:Blood Pressure; D002045:Bupivacaine; D002245:Carbon Dioxide / Q000097:blood; D002585:Cesarean Section; D005260:Female; D005312:Fetal Blood; D005318:Fetal Heart / Q000502:physiology; D006339:Heart Rate; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011247:Pregnancy; D012119:Respiration
D002245:Carbon Dioxide; D010100:Oxygen; D002045:Bupivacaine