Seminoma in a 12-year-old male with 46 XY/45 XO karyotype.
A pure seminoma in a 12-year-old boy with an undescended testis and 46 XY/45 XO karyotype is presented. The relationships between an undescended testis, an abnormal karyotype, dysgenetic gonads and cancer are discussed.
D002648:Child; D002872:Chromosome Deletion; D003456:Cryptorchidism / Q000150:complications / Q000235:genetics*; D004407:Dysgerminoma / Q000150:complications / Q000235:genetics*; D006801:Humans; D008297:Male; D009030:Mosaicism; D012730:Sex Chromosomes; D013736:Testicular Neoplasms / Q000150:complications / Q000235:genetics*; D014998:Y Chromosome