[Metabolic acidosis as a side-effect of methoxyflurane anesthesia (author's transl)].
In 14 patients undergoing surgery with methoxyflurane anaesthesia the development of metabolic acidosis was observed. As mechanisms causing such acidosis regional ischaemia and inhibition of lactic acid metabolism in the liver by breakdown products of methoxyflurane are discussed.
D000005:Abdomen / Q000601:surgery; D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000139:chemically induced*; D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D005260:Female; D006042:Goiter / Q000601:surgery; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008733:Methoxyflurane / Q000009:adverse effects*; D008875:Middle Aged; D014648:Varicose Veins / Q000601:surgery
D008733:Methoxyflurane
Methoxyfluran-Anaesthesie: Metabolische Acidose als Nebenwirkung