Peritoneal dialysis for severe methyprylon intoxication.
The appropriate therapy for methyprylon (Noludar) poisoning has remained controversial, owing to a lack of reliable pharmacologic data concerning the most effective way to remove the drug after a large ingestion. We recently employed peritoneal dialysis to treat a 16-year-old girl, who had ingested 6.3 gm of methypyrlon, and were able to recover more than 80% of the unmetabolized drug in the dialysate. Clinical recovery was complete within eight hours. This appears to be a safe and effective method to remove the drug in the child or adult with a serious intoxication.
D000293:Adolescent; D005260:Female; D006801:Humans; D010530:Peritoneal Dialysis; D010881:Piperidones / Q000506:poisoning*
D010881:Piperidones