The effect of diazepam and lorazepam on awareness during anaesthesia for Caesarian section.
One hundred-and-eighty-three patients having general anaesthesia for Caesarian section were given lorazepam or diazepam intravenously immediately following delivery. The incidence of unpleasant recall was comparable with the reports of other workers. There was no evidence of a specific retrograde amnesic effect by either drug. Neither agent appeared to affect cardiovascular stability, uterine contraction, the reversal of muscle relaxant or the time to recovery of protective reflexes. The patients tended to be drowsier after lorazepam but as safe as after diazepam so far as circulation, respiration and protective reflexes were concerned.
D000328:Adult; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001364:Awareness / Q000187:drug effects*; D002585:Cesarean Section; D003071:Cognition / Q000187:drug effects*; D003975:Diazepam / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000494:pharmacology*; D011247:Pregnancy
D014151:Anti-Anxiety Agents; D008140:Lorazepam; D003975:Diazepam