The isolation of a Bwamba virus variant from man in Western Kenya.
A bwamba group virus was isolated from the blood of a febrile child on the Kano Plain, Kenya. The isolate (NY-45), closely resembling Bwamba, established infection in both Anopheles gambiae and Mansonia uniformis. Neither the Bwamba nor the Pongola prototype strains grew in both species. In gel-diffusion tests NY-45 virus passaged through mosquitoes exhibited a line of identity with Pongola antiserum. In contrast no cross-reaction was observed with NY-45 virus which had not previously been passaged through mosquitoes.
D000328:Adult; D000818:Animals; D001103:Arboviruses / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification*; D001769:Blood / Q000382:microbiology*; D003429:Cross Reactions; D009033:Culicidae / Q000382:microbiology; D006801:Humans; D005779:Immunodiffusion; D007223:Infant; D007630:Kenya; D008297:Male; D009500:Neutralization Tests