Exudative retinal detachment and scleritis in polyarteritis.
A 64-year-old white man, treated with systemic corticosteroids for five years, developed polyarteritis. He then developed a severe scleritis with an exudative retinal detachment in the right eye, which became blind and painful and was enucleated 23 months after onset of the scleritis. Histopathologic examination of the enucleated eye revealed granulomatous scleritis, chronic nongranulomatous uveitis, exudative retinal detachment, and perivasculitis of intrascleral, iris, ciliary body, and retinal blood vessels. Systemic findings were minimal and limited to elevated sedimentation rate, weight loss, mild anemia, and microscopic hematuria. Respiratory disease, severe kidney disease, hypertension, and arthritis were notably absent. A muscle biopsy established the diagnosis.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001766:Blindness / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000473:pathology; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009336:Necrosis; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000188:drug therapy / Q000473:pathology*; D012590:Sclera / Q000473:pathology*
D000305:Adrenal Cortex Hormones; D011241:Prednisone