The effectiveness and duration of preoperative antacid therapy.
The administration of 10 ml of magnesium trisilicate mixture to premedicated patients, maintains the pH of gastric contents below pH 2-5 during subsequent general anaesthesia. This effect was sustained for over seven hours--the longest anaesthetic time studied. No antacid supplementation is required to offer protection from acid aspiration during emergence and initial recovery from general anaesthesia.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects; D000863:Antacids / Q000627:therapeutic use*; D002648:Child; D005260:Female; D005750:Gastric Juice / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D011015:Pneumonia, Aspiration / Q000517:prevention & control*; D011229:Preanesthetic Medication; D011300:Preoperative Care; D013997:Time Factors
D000863:Antacids