[Drug-drug interactions (author's transl)].
This short outline of drug-drug interactions does not claim to cover the entire field. The task of this paper is to illustrate the most important principles of drug-drug interactions by paradigms taken from the experience of the practitioner. One consequence of drug-drug interactions is the change in pharmacolinetic parameters important for the therapeutical effect of drugs in the organism. Very often the elucidation of the mechanisms of drug-drug interactions in man is impossible; therefore, for clinical pharmacologists experiments on animals remain the tool in order to gain more knowledge in this field.
D000367:Age Factors; D001682:Biological Availability; D001711:Biotransformation; D003692:Delayed-Action Preparations; D004304:Dosage Forms; D004336:Drug Antagonism; D004347:Drug Interactions; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005502:Food; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011485:Protein Binding; D013997:Time Factors
D003692:Delayed-Action Preparations; D004304:Dosage Forms; D004364:Pharmaceutical Preparations
Arzneimittelinterferenz (drug-drug interactions)