[The cardiotropic effect of antidepressants in aging patients (author's transl)].
All antidepressants now used have a cardiotropic, for some instances also cardiotoxic effect. This quinidine-like effect prolongs the QT-interval of ECG and can induce reentry and ventricular fibrillation. When quinidine and antidepressants are combined in the same patient the risk of such cardiac complications increases.
D000367:Age Factors; D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004357:Drug Synergism; D004562:Electrocardiography; D006321:Heart / Q000187:drug effects*; D006801:Humans; D011802:Quinidine / Q000009:adverse effects
D000928:Antidepressive Agents; D011802:Quinidine
Zur frage der kardiotropen Wirkung von Antidepressiva insbesondere bei Alterspatienten.