Serum gastrin levels before and after 6 weeks of cimetidine therapy in patients with duodenal ulcer.
Fasting serum gastrins were carried out at the beginning and end of a 6-week double-blind trial of cimetidine and placebo in 30 patients with duodenal ulcer. Cimetidine did not cause any significant change in fasting serum gastrin levels after 6 weeks of therapy.
D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004381:Duodenal Ulcer / Q000188:drug therapy*; D005755:Gastrins / Q000097:blood* / Q000378:metabolism; D006146:Guanidines / Q000627:therapeutic use*; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D007093:Imidazoles; D010919:Placebos; D012636:Secretory Rate / Q000187:drug effects; D013997:Time Factors
D005755:Gastrins; D006146:Guanidines; D006635:Histamine H2 Antagonists; D007093:Imidazoles; D010919:Placebos