The chemical structure of prostaglandin X (prostacyclin).
The chemical structure of prostaglandin X, the anti-aggregatory substance derived from prostaglandin endoperoxides, is 9-deoxy-6, 6alpha-epoxy-delta5-PGF1alpha. The stable compound formed when prostaglandin X undergoes a chemical transformation in biological systems in 6-keto-PGF1alpha. Prostaglandin X is stabilized in aqueous preparations by raising the pH to 8.5 or higher. The trivial name prostacyclin is proposed for 9-deoxy-6, 9alpha-epoxy-delta5-PGF1alpha.
D000818:Animals; D001011:Aorta / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas; D006863:Hydrogen-Ion Concentration; D013058:Mass Spectrometry; D008861:Microsomes / Q000378:metabolism; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010545:Peroxides; D010974:Platelet Aggregation / Q000187:drug effects; D011453:Prostaglandins / Q000494:pharmacology; D011460:Prostaglandins F / Q000378:metabolism / Q000494:pharmacology; D013552:Swine
D010545:Peroxides; D011453:Prostaglandins; D011460:Prostaglandins F