Substrate and inhibitor complexes of dihydrofolate reductase from amethopterin-resistant L1210 cells.
D000818:Animals; D001665:Binding Sites; D002478:Cells, Cultured; D004351:Drug Resistance; D004591:Electrophoresis, Polyacrylamide Gel; D007939:Leukemia L1210 / Q000201:enzymology*; D008727:Methotrexate / Q000494:pharmacology*; D009249:NADP; D011485:Protein Binding; D011487:Protein Conformation; D013056:Spectrophotometry, Ultraviolet; D013762:Tetrahydrofolate Dehydrogenase / Q000302:isolation & purification / Q000378:metabolism*
D009249:NADP; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate