[Local contractility and acidosis in the ischemic myocardium of the dog (author's transl)].
In open chest dogs up to 8 side branches of the R, circumflexus and descendens were embraced and could selectively be occluded. With a new developed method local myocardial length changes in the ischemic areas, and with H+-sensitive minielectrodes the interstitial H+-activities were measured. All changes which were observed during the 3-30 min lasting coronary artery occlusions (H+-increases to about 500 neq/1, increases of diastolic length, decreases of the contraction amplitude, ST-elevations) returned to preocclusion levels during reperfusion. LVP and dp/dt remained unchanged during ischemia and reperfusion.
D000818:Animals; D003327:Coronary Disease / Q000503:physiopathology*; D004285:Dogs; D004562:Electrocardiography; D006334:Heart Function Tests / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D009200:Myocardial Contraction
Messungen der lokalen Kontraktilität und Acidose im ischämischen Hundemyokard.