Incorporation of mannose and glucose into prenylphosphate sugars in isolated human platelet membranes.
Isolated platelet membranes synthesize mannosylretinyl phosphate and dolichylmannosyl phosphate from GDP-[14C]mannose, but only dolichylglucosyl-phosphate is synthesized from UDP-[14C]glucose. Addition of exogenous retinylphosphate specifically stimulates the biosynthesis of mannosylretinylphosphate.
D001786:Blood Glucose / Q000378:metabolism*; D001792:Blood Platelets / Q000378:metabolism*; D002413:Cations, Divalent; D002414:Cations, Monovalent; D002462:Cell Membrane / Q000378:metabolism; D006017:Glycolipids / Q000097:blood; D006155:Guanosine Diphosphate Mannose / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008358:Mannose / Q000097:blood*; D009943:Organophosphorus Compounds / Q000097:blood; D013729:Terpenes / Q000097:blood*; D014532:Uridine Diphosphate Glucose / Q000378:metabolism
D001786:Blood Glucose; D002413:Cations, Divalent; D002414:Cations, Monovalent; D006017:Glycolipids; D009943:Organophosphorus Compounds; D013729:Terpenes; D006155:Guanosine Diphosphate Mannose; D008358:Mannose; D014532:Uridine Diphosphate Glucose