[Double-blind comparison of parsalmide and diazepam in anxious and depressive neurotic syndromes].
Parsalmide- a new drug- is effective in the relief of inflammation and pain. In a double-blind, between-patients, cross-over trial with diazepam in 16 subjects with anxiety and depression, however, it proved less successful in relieving anxiety, though it was on a par with diazepam on an overall evaluation. The daytime somnolence and asthenia observed with diazepam were not observed with parsalmide.
D000275:Adjustment Disorders / Q000188:drug therapy*; D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000188:drug therapy*; D001549:Benzamides / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D014151:Anti-Anxiety Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001549:Benzamides; D003975:Diazepam
Confronto a "cecità doppia" tra parsalmide e diazepam nelle sindromi nevrotiche ansioso-depressive