Autoantibodies in sera of influenza patients.
Sera of the influenza patients and healthy controls were tested for some types of autoantibody (SMA, ANA, ABBA, AMA). They were detected in 83.8% of the patients' sera and in 16.6% of controls. SMA were present in 77.4%, ANA in 54.8%, and ABBA in 16.1% of the patient's sera. AMA were not detected. A majority of the sera contained more than one autoantibody type. The possible mechanisms of induction of the autoantibodies in virus infection and their possible role in disease are briefly discussed.
D000205:Actomyosin / Q000276:immunology; D000293:Adolescent; D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D002467:Cell Nucleus / Q000276:immunology; D005260:Female; D006801:Humans; D007251:Influenza, Human / Q000276:immunology*; D007687:Kidney Tubules, Proximal / Q000276:immunology; D008297:Male; D008875:Middle Aged; D008931:Mitochondria, Muscle / Q000276:immunology; D009130:Muscle, Smooth / Q000276:immunology / Q000648:ultrastructure
D001323:Autoantibodies; D000205:Actomyosin