[Studies of the effects of an injectable combination of a local anaesthetic with a beta-receptor-blocker (author' transl)].
The use of an injectable combination of a local anaesthetic (Xylestesin) and a beta-receptor-blocker (Betadrenol) during maxillo-facial surgery is described in this paper. The statistical analysis of pulse and blood pressure recordings of 30 patients demonstrated no significant blood pressure changes; there was a significant decrease of the cardiac rate, however. It was noted that the negative chronotropic effect was the greater the higher the rate rate was before injection. The local anaesthetic described is of great therapeutic value, in particular for apprehensive patients and patients with tachycardia.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000328:Adult; D000772:Anesthesia, Local; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D004347:Drug Interactions; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology*; D008297:Male; D008443:Maxillary Sinus / Q000601:surgery; D008875:Middle Aged
D000319:Adrenergic beta-Antagonists; D004338:Drug Combinations; D008012:Lidocaine
Untersuchungen zur Wirking eines Lokalanaesthetikums in Kombination mit einem beta-Rezeptorenblocker