The use of a single venous blood sample to assess oxygen binding in haemoglobin.
The measurement of pH, PO2, PCO2 and SO2 in a single venous blood sample can be used to determine the P50 at standard or at in vivo conditions. This technique makes it feasible for a physician, firstly, to make an assessment of the net adaptation of the red cell to reductions in blood oxygen content or flow and, secondly, to make an initial assessment of whether a haemoglobin with altered affinity for oxygen is present in subjects with polycythaemia or anaemia.
D000138:Acidosis / Q000097:blood; D000471:Alkalosis / Q000097:blood; D000740:Anemia / Q000097:blood; D000755:Anemia, Sickle Cell / Q000097:blood; D001800:Blood Specimen Collection; D001831:Body Temperature; D003327:Coronary Disease / Q000097:blood; D005260:Female; D005312:Fetal Blood; D006333:Heart Failure / Q000097:blood; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008722:Methods; D010100:Oxygen / Q000097:blood*; D014680:Veins
D006454:Hemoglobins; D010100:Oxygen