[Psychophysiologic characteristics of the individual psychotropic activity of benzodiazepine derivatives under experimental conditions].
In 156 experiments performed on 41 cats with adequate experimental models of pseudoneurotic conditions, states of anxiety due to an electrostimulation of the hypothalamus through implanted electrodes and an emotional stress due to a conflict situation the authors compared the individual traits of the psychotropic activity of lorazepam, diazepam, chlordiazepoxide, oxazepam, nirazepam. These experiments permitted to display significant differences of psychophysiological structures in the tranquilizing effect of 5 benzodiazepine derivatives.
D000818:Animals; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy*; D002415:Cats; D002707:Chlordiazepoxide / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D006801:Humans; D008140:Lorazepam / Q000627:therapeutic use; D009497:Neurotic Disorders / Q000188:drug therapy*; D009567:Nitrazepam / Q000627:therapeutic use; D010076:Oxazepam / Q000627:therapeutic use; D013315:Stress, Psychological / Q000187:drug effects*
D014151:Anti-Anxiety Agents; D010076:Oxazepam; D002707:Chlordiazepoxide; D009567:Nitrazepam; D008140:Lorazepam; D003975:Diazepam
Psikhofiziologicheskaia kharakteristika individual'noĭ psikhotropnoĭ aktivnosti benzodiazepinovykh proizvodnykh v usloviiakh éksperimenta.