Effects of D-glyceraldehyde and 3-o-methylglucose upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets.
In perfused pancreatic islets, the fluorescence of reduced pyridine nucleotides was recorded continuously, D-Glyceraldehyde (5 mM) or 3-o-methylglucose (27.5 mM) never caused a net fluorescence increase. Since stepwise changes of the D-glucose concentration between 0 and 20 mM always induced a fluorescence increase, it is concluded that glucose on the one hand and glyceraldehyde or 3-o-methylglucose on the other hand cause different metabolic states in pancreatic islets.
D000818:Animals; D005260:Female; D005947:Glucose / Q000378:metabolism; D005985:Glyceraldehyde / Q000378:metabolism*; D007515:Islets of Langerhans / Q000378:metabolism*; D008297:Male; D008757:Methylglucosides / Q000378:metabolism*; D008759:Methylglycosides / Q000378:metabolism*; D051379:Mice; D008820:Mice, Obese; D009243:NAD / Q000378:metabolism*; D009249:NADP / Q000378:metabolism*; D051381:Rats
D008757:Methylglucosides; D008759:Methylglycosides; D009243:NAD; D005985:Glyceraldehyde; D009249:NADP; D005947:Glucose