Kinetics of drug decomposition. Part 47. Effect of substituents on photochemical stability of perazine derivatives.
A quantum yield phi of photooxidation of perazine derivatives estimated actinometrically and the pKa, values were used for the correlation with the substituent volumes. The Hammett type plots of phi= f(sigma) and phi= f(pKa10--pKa1) are discussed.
D014150:Antipsychotic Agents / Q000528:radiation effects*; D055598:Chemical Phenomena; D002621:Chemistry; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D010464:Perazine / Q000031:analogs & derivatives / Q000528:radiation effects*; D010777:Photochemistry; D014466:Ultraviolet Rays
D014150:Antipsychotic Agents; D010464:Perazine