[Relationship between the antibacterial activity and the acceptor properties of certain penicillins].
Antibacterial activity of 2 natural and 12 semisynthetic penicillins against 5 strains of grampositive bacteria was determined and quantum chemical estimation of their molecules was performed with the Hukkel method. The data were indicative of the fact that antibacterial activity of the penicillins was connected with the acceptor properties of their molecules.
D001419:Bacteria / Q000187:drug effects*; D001665:Binding Sites; D004755:Enterobacteriaceae / Q000187:drug effects; D008087:Listeria / Q000187:drug effects; D008968:Molecular Conformation; D010406:Penicillins / Q000494:pharmacology*; D011789:Quantum Theory; D013211:Staphylococcus aureus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects; D013296:Streptococcus pneumoniae / Q000187:drug effects; D013329:Structure-Activity Relationship
D010406:Penicillins
O zavisimosti mezhdu antibakterial'noĭ aktivnost'iu i aktseptornymi svoĭstvami nekotorykh penitsillinov