Assimilation of ammonia and growth of biotin deficient Aspergillus nidulans.
Biotin deficiency in Aspergillus nidulans has been found to increase the uptake of ammonium ions, associated with a marked increase in the activity of NADP-linked glutamate dehydrogenase, which is found to be the major route of ammonia assimilation in this culture. The results obtained are discussed with respect to the growth of Aspergillus nidulans during biotin deficiency.
D000409:Alanine / Q000378:metabolism; D000594:Amino Acid Oxidoreductases / Q000378:metabolism; D000641:Ammonia / Q000378:metabolism*; D001233:Aspergillus nidulans / Q000378:metabolism*; D001361:Avitaminosis / Q000378:metabolism*; D001710:Biotin / Q000172:deficiency; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D005970:Glutamate Synthase / Q000378:metabolism; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism
D009243:NAD; D009249:NADP; D001710:Biotin; D000641:Ammonia; D000594:Amino Acid Oxidoreductases; D005970:Glutamate Synthase; D005969:Glutamate Dehydrogenase; D005974:Glutamate-Ammonia Ligase; D000409:Alanine