Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin.
D000818:Animals; D002374:Catalase / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System; D003579:Cytochrome Reductases / Q000378:metabolism; D003630:Daunorubicin / Q000378:metabolism* / Q000494:pharmacology; D004317:Doxorubicin / Q000378:metabolism* / Q000494:pharmacology; D005609:Free Radicals; D050356:Lipid Metabolism; D008862:Microsomes, Liver / Q000378:metabolism*; D009249:NADP; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D010544:Peroxidases / Q000378:metabolism; D051381:Rats
D005609:Free Radicals; D009249:NADP; D004317:Doxorubicin; D003577:Cytochrome P-450 Enzyme System; D010544:Peroxidases; D002374:Catalase; D003579:Cytochrome Reductases; D003630:Daunorubicin