Changes in gastric secretion following administration of preparations affecting the parasympathetic and sympathetic nervous system.
The changes in gastric secretion following administration of different preparations have been studied in  a group of 180 patients with duodenal ulcer and chronic gastritis. In patients with hypersecretion the medication with bishpan and inderal as compared with atropine caused considerable shifts in the indices of gastric secretion. Isoproterenol exerted a stimulating influence both on initial hyper- and hyposecretion, while the other preparations studied were shown not to cause any essential rise in gastric secretion in patients with secretory deficiency. Reliable changes of the stimulated gastric secretion were observed only after inderal. The data obtained can be useful when choosing a rational method for the therapy of gastric scretory disorders.
D001285:Atropine / Q000494:pharmacology; D004381:Duodenal Ulcer / Q000503:physiopathology; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D005756:Gastritis / Q000503:physiopathology; D006801:Humans; D007545:Isoproterenol / Q000494:pharmacology; D010276:Parasympatholytics / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D012636:Secretory Rate / Q000187:drug effects; D013566:Sympathomimetics / Q000494:pharmacology*
D010276:Parasympatholytics; D000644:Quaternary Ammonium Compounds; D013566:Sympathomimetics; D001285:Atropine; D007545:Isoproterenol