Conditions for tracheal intubation following fazadinium and pancuronium.
Intubating conditions were studied in two groups of patients who received either fazadinium 1 mg/kg or pancuronium 0.1 mg/kg (group 1), or either fazadinium 0.5 mg/kg or pancuronium 0.08 mg/kg (group 2). In group 1 intubating conditions were studied at 30, 45, 60 and 75 s after injection of the relaxant drug, and in group 2 at 60 s after injection. Fazadinium provided better intubating conditions than pancuronium during the first 60 s after administration in group 1 (P less than 0.01). In group 2 there was no significant difference between the conditions provided by the two drugs.
D006801:Humans; D007442:Intubation, Intratracheal; D009126:Muscle Relaxation; D010197:Pancuronium; D011726:Pyridinium Compounds; D013997:Time Factors
D011726:Pyridinium Compounds; D010197:Pancuronium