Isolation and characterization of the cardiotonic polypeptide anthopleurin-A from the sea anemone Anthopleura xanthogrammica.
A highly potent cardiotonic polypeptide, anthopleurin-A, was isolated from the sea anemone, Anthopleura xanthogrammica (Brandt), using solvent partition, gel permeation chromatography, and cation-exchange chromatography. It is a pure basic polypeptide wtih a molecular weight of about 5500.
D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003063:Cnidaria / Q000032:analysis*; D004589:Electrophoresis, Disc; D036341:Intercellular Signaling Peptides and Proteins; D007525:Isoelectric Focusing; D009200:Myocardial Contraction / Q000187:drug effects; D010455:Peptides / Q000302:isolation & purification* / Q000494:pharmacology; D012615:Sea Anemones / Q000032:analysis*
D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; C012746:anthopleurin-A