Resistance to Marek's disease. Effect of Corynebacterium parvum and Marek's tumor cell vaccines on tumorigenesis in chickens.
A study of nonspecific stimulation of the avian immune system with Corynebacterium parvum and specific stimulation with Marek's tumor cell vaccines revealed that nonspecifically stimulated outbred White Leghorn-type cockerels had higher incidences of tumors than did controls. A study of tumor cell cytotoxicity of sera from Marek's disease virus exposed birds indicated that humoral factors may play some role in tumor resistance.
D000818:Animals; D000951:Antigens, Neoplasm / Q000008:administration & dosage*; D002060:Bursa of Fabricius / Q000276:immunology; D002645:Chickens; D006087:Graft vs Host Reaction; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D007167:Immunotherapy; D008380:Marek Disease / Q000276:immunology* / Q000517:prevention & control / Q000628:therapy; D011425:Propionibacterium acnes / Q000276:immunology*
D000951:Antigens, Neoplasm