Prostatic maldevelopment in the prune belly syndrome: a defect in prostatic stromal-epithelial interaction.
The prune belly syndrome consists of a triad of abdominal wall musculature deficiency, cryptorchidism and urinary tract anomalies. A rarely described but fairly constant component of the syndrome is the lack of development of the epithelial elements of the prostate. We wish to suggest that this is a further expression of a postulated arrest in mesenchymal development responsible for other features of the syndrome.
D000009:Abdominal Muscles / Q000002:abnormalities*; D000015:Abnormalities, Multiple / Q000473:pathology; D001344:Autopsy; D003456:Cryptorchidism / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D011467:Prostate / Q000002:abnormalities* / Q000473:pathology; D013577:Syndrome; D014564:Urogenital Abnormalities