[Structural changes in sarcolemma with E-avitaminosis dystrophy].
Sorption properties of sarcolemma preparations isolated from skeletal muscles of normal and E-avitaminous rabbits were studied relative to organic ions. Analysis of isotherms of sarcolemma equilibrium binding of neutral red cations and turquoise direct lightfast "K" anions made it possible to determine the number of positively and negetively charged sorption centres, which fix the mentioned dyes. With E-avitaminous muscular dystrophy the number of the centres increases considerably. A larger number of the positively charged centres fixing the surquoise dye are found both in the control and in case of dystrophy. The calcium ions prevent the neutral red sorption and intensify the turquoise direct sorption. In the sarcolemma preparations isolated from the muscles of the E-avitaminous rabbits the content of calcium ions is almost twice as high and the number of sulphydryl groups is 30-40% less as compare to the normal level. The data presented evidence for structural changes in sarcolemma with E-avitaminous muscular dystrophy.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D004396:Coloring Agents / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D009137:Muscular Dystrophy, Animal / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D009499:Neutral Red / Q000378:metabolism; D011485:Protein Binding; D011817:Rabbits; D012508:Sarcolemma / Q000378:metabolism* / Q000473:pathology; D013438:Sulfhydryl Compounds; D014811:Vitamin E Deficiency / Q000150:complications / Q000378:metabolism* / Q000473:pathology
D004396:Coloring Agents; D013438:Sulfhydryl Compounds; D009499:Neutral Red; D002118:Calcium
Strukturni zmini v sarkolemi za E-avitaminoznoĭ distrofii.