The narcotic discriminative stimulus complex: relation to analgesic activity.
The ability of drugs to produce the narcotic discriminative stimulus complex is found to be highly correlated with their analgesic activity; in contrast, no relation with their antidiarrhoeal activity is evident. The findings suggest that the narcotic discriminative stimulus complex is a centrally mediated effect of narcotic drugs.
D000701:Analgesics, Opioid / Q000494:pharmacology*; D000818:Animals; D000930:Antidiarrheals / Q000494:pharmacology*; D002368:Castor Oil / Q000037:antagonists & inhibitors; D004192:Discrimination, Psychological / Q000187:drug effects*; D008297:Male; D051381:Rats
D000701:Analgesics, Opioid; D000930:Antidiarrheals; D002368:Castor Oil