Retransfusion acidosis after brief haemorrhagic hypotension in the dog.
Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; concurrently, PaCO2 rose by 9.2-12.9 mm Hg. A close correlation was demonstrated between these changes. After retransfusion, PaO2 and the arterial lactic acid level did not change significantly. Thus retransfusion acidosis in the dog appears after a brief hypotensive period, too, but cannot be attributed to a "washout" of lactate from the tissues.
D000138:Acidosis / Q000209:etiology*; D000818:Animals; D001794:Blood Pressure; D001804:Blood Transfusion, Autologous; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs; D005260:Female; D006470:Hemorrhage / Q000150:complications*; D006863:Hydrogen-Ion Concentration; D007022:Hypotension / Q000150:complications*; D007773:Lactates / Q000097:blood; D008297:Male; D010100:Oxygen / Q000097:blood
D007773:Lactates; D002245:Carbon Dioxide; D010100:Oxygen