Engraftment of allogeneic dog bone marrow.
Resistance to allogeneic bone-marrow grafts (AR) was found to occur in many species, including the dog. The i.v. administration of silica particles suppressed AR in vivo in this species. Genetic studies provide suggestive evidence for the existence of a previously unrecognized system or systems in the canine major histocompatibility complex controlling AR.
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology; D001215:Asparaginase / Q000494:pharmacology; D001772:Blood Cell Count; D001792:Blood Platelets; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002272:Carcinoembryonic Antigen / Q000032:analysis; D004285:Dogs; D006087:Graft vs Host Reaction; D006649:Histocompatibility Antigens; D007165:Immunosuppression Therapy; D007621:Karyotyping; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000473:pathology; D007959:Lymphocyte Culture Test, Mixed; D012156:Reticulocytes; D012822:Silicon Dioxide / Q000494:pharmacology; D013154:Spleen / Q000473:pathology; D014184:Transplantation, Homologous
D000961:Antilymphocyte Serum; D002272:Carcinoembryonic Antigen; D006649:Histocompatibility Antigens; D012822:Silicon Dioxide; D001215:Asparaginase