Increased acquisition of a complex appetitive task after MSH and MIF.
After daily injections of melanocyte stimulating hormone (MSH), MSH-release inhibiting factor (MIF), or diluent albino rats ran a 12 choice Warden maze for a palatable food reward. Rats receiving the hormones had shorter latencies and made fewer errors than controls during learning but, unlike results with simple tasks, there were no differences during extinction. The results demonstrated that both MSH and MIF-I could facilitate the acquisition of an appetitive task which seemed of sufficient complexity to emphasize differences in performance.
D000818:Animals; D001070:Appetitive Behavior / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D005108:Extinction, Psychological / Q000187:drug effects; D009075:MSH Release-Inhibiting Hormone / Q000494:pharmacology*; D008297:Male; D009074:Melanocyte-Stimulating Hormones / Q000494:pharmacology*; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D013268:Stimulation, Chemical; D013997:Time Factors
D009074:Melanocyte-Stimulating Hormones; D009075:MSH Release-Inhibiting Hormone