[Surgery of pancreatic endocrine tumours in the German Federal Republic: results of a survey (author's transl)].
Within a ten-year scan (1967-1976) 207 insulinomas, 50 gastrinomas, 8 Verner-Morrison tumors, 5 glucagonomas and 12 endocrine pancreatic tumours with associated MEA syndrome (multiple endocrine adenomatosis) were treated surgically at various university hospitals (information obtained by questionnaire). Half of the insulinomas were treated by enucleation, one third by resection of the tail of the pancreas. Total gastrectomy was the procedure of choice in 80% of patients with gastrinoma, but sometimes pancreatic resection to remove the tumour was added. An new therapeutic concept of using histamine-H2 receptor antagonists for treating patients with Zollinger-Ellison syndrome is discussed. In the eight patients with a Verner-Morrison syndrome removal of the tumour or distal pancreatic resection was the procedure of choice.
D058186:Acute Kidney Injury / Q000601:surgery; D007516:Adenoma, Islet Cell / Q000601:surgery; D003681:Dehydration / Q000601:surgery; D005743:Gastrectomy; D005755:Gastrins / Q000378:metabolism; D005934:Glucagon / Q000378:metabolism; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D009362:Neoplasm Metastasis; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000601:surgery*; D013223:Statistics as Topic; D013577:Syndrome; D015043:Zollinger-Ellison Syndrome / Q000188:drug therapy
D005755:Gastrins; D006635:Histamine H2 Antagonists; D005934:Glucagon
Chirurgie des endokrinen Pankreas in der Bundesrepublik.