[Comparative assessment of the effect of sympatholytics and beta-adrenoblockaders on carbohydrate-phosphorus metabolic indices in the myocardium of growing rats].
The sympatholyitic ornide and beta-adrenoblocking agent alpheprol were introduced intraperitoneally in single doses of 5 and 1 mg/kg, respectively to 7--30 day and 3--5-month old adult rats. The content of ATP, ADP, AMP, inorganic phosphorus glycogen and also active P32 incorporation were determined. The 7-day old rattlings are shown to be more sensitive to ornide than to alpheprol by comparison with older animals.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000367:Age Factors; D000818:Animals; D050260:Carbohydrate Metabolism; D006128:Growth / Q000187:drug effects*; D006321:Heart / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism*; D010758:Phosphorus / Q000378:metabolism*; D051381:Rats; D013565:Sympatholytics / Q000494:pharmacology*
D000319:Adrenergic beta-Antagonists; D013565:Sympatholytics; D010758:Phosphorus
Sravnitel'naia otsenka vliianiia simpatolitikov i beta-adrenoblokatorov na nekotorye pokazateli uglevodno-fosfornogo obmena v miokarde rastushchikhkrys.