Saccharin inhibits guanylate cyclase activity: possible relationship to carcinogenesis.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006162:Guanylate Cyclase / Q000037:antagonists & inhibitors*; D008297:Male; D009369:Neoplasms / Q000139:chemically induced; D051381:Rats; D012439:Saccharin / Q000494:pharmacology* / Q000652:urine; D001743:Urinary Bladder / Q000201:enzymology
D006162:Guanylate Cyclase; D012439:Saccharin