Phosphatidate phosphohydrolase and palmitoyl coenzyme A hydrolase in cardiac subcellular fractions.
The characteristics of the two enzymes related to fatty acid esterifaction were studied in order to provide fundamental information leading to further understanding of the control of myocardial glyceride formation. Palmitoyl-CoA hydrolase and phosphatidate phosphohydrolase are both distributed unevenly among heart subcellular fractions. The activity of the latter enzyme in subcellular fractions changes independently in response to Mg2+ addition and in response to thyroid hormone treatment of animals.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D009206:Myocardium / Q000201:enzymology* / Q000648:ultrastructure; D010168:Palmitates; D010712:Phosphatidic Acids; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D011817:Rabbits; D013347:Subcellular Fractions / Q000201:enzymology*; D013869:Thiolester Hydrolases / Q000378:metabolism; D014284:Triiodothyronine / Q000494:pharmacology
D010168:Palmitates; D010712:Phosphatidic Acids; D014284:Triiodothyronine; D013869:Thiolester Hydrolases; D010744:Phosphoric Monoester Hydrolases; D008274:Magnesium