[Effect of beta-adrenergic stimulation on the closing volume in normal subjects (author's transl].
In 12 normal subjets we studies the effects of beta-adrenergic stimulation (Salbutamol, 500 microgram inhaled) on the closing volume (CV) and the closing capacity and on the ratios of these indexes to the vital capacity (VC) and the total lung capacity, respectively. CV and CV/VC % increased in ten subjects wereas it decreased in two subjects. On an average, the changes  were small but significant (p less than 0.01) and could be duplicated in four subjects. Similar studies have yielded variable results. The reasons for those variation could be attributed either to technical or/and individual differences in the resulting effect of beta stimulation on respiratory mechanics.
D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000328:Adult; D000420:Albuterol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000187:drug effects*; D014109:Total Lung Capacity; D014797:Vital Capacity / Q000187:drug effects
D000318:Adrenergic beta-Agonists; D000420:Albuterol
Action d'un beta-stimulant adrénergique sur le volume de fermeture des sujects normax.