Cataract and gamma-glutamyl cycle in myotonic dystrophy.
Gamma-Glutamyl transpeptidase (gamma-GT) may be responsible for the rapid catabolism and low levels of lenticular glutathione often associated with cataract formation. Elevated levels of serum gamma-GT in patients with myotonic dystrophy suggest that since the defect could be present in all tissues it might be responsible for the cataracts frequently observed in this genetic disease.
D000328:Adult; D002386:Cataract / Q000150:complications / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D009223:Myotonic Dystrophy / Q000150:complications / Q000201:enzymology*; D005723:gamma-Glutamyltransferase / Q000097:blood*
D005723:gamma-Glutamyltransferase