[Capability of lymphocytes, stimulated in vitro with phytohemagglutinins to accomplish the graft versus host reaction].
Lymph node cells from CBA mice cultivated in the presence of PHA for 2 hours proved to be more potent, and for 44 hours--less potent as compared with normal non-cultivated cells in their capacity to realize the GVHR after injection to sublethally irradiated (CBAXC57BL) F1 recipients. Syngeneic or killed allogeneic lymphocytes cultivated similarly and phytohemagglutinin were found to be deprived of this potency.
D000818:Animals; D006087:Graft vs Host Reaction; D037102:Lectins / Q000494:pharmacology; D008213:Lymphocyte Activation; D017710:Lymphocyte Transfusion; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D014184:Transplantation, Homologous
D037102:Lectins
Sposobnost' limfotsitov, stimulirovannykj in vitro fitogemaggliutinnom, osushchestvliat'reaktsiiu transplantat protiv khoziaina