Behavioral rhythms in schizophrenia.
Daily behavioral observations were made for several years on 10 male schizophrenic patients and on three male patients with organic brain disorders. Analysis of these data showed strong cyclic components in the five schizophrenic patients with predominantly hebephrenic symptomatology. Period lengths noted were about 2 days, 5 to 6 days, 30 days, and a longer cycle of 40 to 100 days duration. Antipsychotic medications appear to have a suppressant effect, but tricyclic antidepressants may enhance pre-existing rhythms.
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000523:psychology; D010507:Periodicity; D012559:Schizophrenia / Q000188:drug therapy; D012560:Schizophrenia, Catatonic / Q000523:psychology; D012562:Schizophrenia, Disorganized / Q000523:psychology; D012563:Schizophrenia, Paranoid / Q000523:psychology; D012565:Schizophrenic Psychology; D013997:Time Factors
D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents