Drug kinetics and artificial kidneys.
The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of drug kinetics are well described. However, studies of the effects of artificial kidneys on drug kinetics have often been limited by a lack of attention to proper methods of calculating solute clearance by the artificial kidney.
D000700:Analgesics / Q000378:metabolism; D014151:Anti-Anxiety Agents / Q000378:metabolism; D000889:Anti-Arrhythmia Agents / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000378:metabolism; D002301:Cardiac Glycosides / Q000378:metabolism; D006207:Half-Life; D006801:Humans; D006993:Hypnotics and Sedatives / Q000378:metabolism; D007688:Kidneys, Artificial; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011485:Protein Binding; D006435:Renal Dialysis
D000700:Analgesics; D014151:Anti-Anxiety Agents; D000889:Anti-Arrhythmia Agents; D000900:Anti-Bacterial Agents; D002301:Cardiac Glycosides; D006993:Hypnotics and Sedatives; D004364:Pharmaceutical Preparations