Calcium ion as second messenger.
The role of calcium as an intracellular messenger in the activation of eukaryotic cells is discussed. Particular emphasis is devoted to: (1) the interrelationship between cell activation by chemical stimuli and alterations in intracellular calcium metabolism, and (2) the interrelated roles of calcium and the cyclic nucleotides, cyclic AMP and cyclic GMP, in achieving the final integrated, co-ordinated cellular response.
D000262:Adenylyl Cyclases / Q000378:metabolism; D001692:Biological Transport; D002118:Calcium / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D002395:Catecholamines / Q000502:physiology; D000242:Cyclic AMP / Q000502:physiology*; D006152:Cyclic GMP / Q000502:physiology*; D004912:Erythrocytes / Q000378:metabolism*; D006162:Guanylate Cyclase / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D007473:Ion Channels / Q000378:metabolism; D008928:Mitochondria / Q000502:physiology; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000378:metabolism; D011941:Receptors, Adrenergic / Q000502:physiology
D002395:Catecholamines; D007473:Ion Channels; D011941:Receptors, Adrenergic; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D006162:Guanylate Cyclase; D006152:Cyclic GMP; D002118:Calcium