A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system.
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003580:Cytochromes / Q000378:metabolism*; D004790:Enzyme Induction / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008566:Membranes / Q000201:enzymology; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D010634:Phenobarbital / Q000494:pharmacology; D011284:Pregnenolone / Q000031:analogs & derivatives / Q000494:pharmacology; D051381:Rats; D014316:Tritium; D015049:Zoxazolamine / Q000378:metabolism*
D003580:Cytochromes; D014316:Tritium; D008748:Methylcholanthrene; D011284:Pregnenolone; D003577:Cytochrome P-450 Enzyme System; D015049:Zoxazolamine; D010634:Phenobarbital