Properties of sarcolemmal delayed rectification in glycerol-treated fibers of frog sartorius muscle.
Total current-voltage relations were analyzed on nine glycerol-treated surface fibers of frog sartorius muscles in tetrodotoxin-containing isotonic normal Ringer solution. The results indicate that delayed rectification occurs in the sarcolemma on large depolarization and that delayed rectification is only partially inactivated during 1 sec of depolarization and not converted into anomalous rectification. The time to peak, the time course of inactivation and the potassium activation potential determined in glycerol-treated fibers were comparable to those analyzed previously in intact fibers. The value of the conductance increase during delayed rectification in glycerol-treated fibers appeared to be smaller than that in intact fibers.
D000818:Animals; D001001:Anura; D004553:Electric Conductivity; D005990:Glycerol / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008564:Membrane Potentials; D009132:Muscles / Q000187:drug effects* / Q000502:physiology; D011892:Rana catesbeiana; D012508:Sarcolemma / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors
D005990:Glycerol