Vasculitis with hepatitis B antigenemia: long-term observation in nine patients.
The development of generalized necrotizing vasculitis in association with hepatitis B antigenemia is the first example in man of a chronic rheumatic disease presumably caused by a viral infection. This report reviews the experience in nine biopsy-proven cases of hepatitis B-associated necrotizing vasculitis followed for up to six years. The natural history of the disease is emphasized and the manifestations of patients with vasculitis who carry hepatitis B antigen are compared with those of vasculitis patients who are antigen negative.
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D006506:Hepatitis A / Q000276:immunology*; D006511:Hepatitis B Antigens / Q000032:analysis*; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000175:diagnosis / Q000209:etiology / Q000276:immunology* / Q000473:pathology
D006511:Hepatitis B Antigens