Clinical evaluation of injectable lorazepam as a premedicant: the effect on recall.
A double-blind comparison of lorazepam and placebo, lorazepam and pentobarbital, and a comparison of lorazepam IV drip versus lorazepam IV bolus as a premedicant showed this new agent to offer promise as a sedative premedicant. However, the potency of the drug demands caution, and its use for outpatient premedication is not recommended.
D000771:Anesthesia, Intravenous; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D006801:Humans; D007263:Infusions, Parenteral; D007275:Injections, Intravenous; D008140:Lorazepam / Q000008:administration & dosage / Q000494:pharmacology*; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects*; D010424:Pentobarbital / Q000494:pharmacology; D010919:Placebos; D011229:Preanesthetic Medication
D014151:Anti-Anxiety Agents; D010919:Placebos; D010424:Pentobarbital; D008140:Lorazepam