Differential influence of block of catechol-O-methyl transferase (COMT) activity and of neuronal uptake on alpha- and beta-adrenergic effects.
D000818:Animals; D065098:Catechol O-Methyltransferase Inhibitors; D003042:Cocaine / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology; D007583:Jejunum / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D009474:Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology; D010656:Phenylephrine / Q000494:pharmacology; D010883:Piperoxan / Q000494:pharmacology; D011427:Propiophenones / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011817:Rabbits; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*
D065098:Catechol O-Methyltransferase Inhibitors; D011427:Propiophenones; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D010656:Phenylephrine; D011433:Propranolol; D010883:Piperoxan; D003042:Cocaine; D007545:Isoproterenol; D009638:Norepinephrine; D004837:Epinephrine