Synthesis of certain benzo- and pyridodiazepines likely to possess tranquilizing effect.
The synthesis of certain 1.5-benzodiazepinediones, some of their oxygen-free analogues and a number of the 7-nitro derivatives is described. Condensation of 3.4-diaminopyridine with diethylmalonate instead of affording the expected pyridodiazepine, yielded an imidazopyridine, the structure of which was inferred from spectral data Nevertheless, the pyridodiazepine was obtained by condensing the diamino-heterocycle with malonyl dichloride.
D014151:Anti-Anxiety Agents / Q000138:chemical synthesis*; D001569:Benzodiazepines; D055598:Chemical Phenomena; D002621:Chemistry; D009682:Magnetic Resonance Spectroscopy; D014149:Tranquilizing Agents / Q000138:chemical synthesis*
D014151:Anti-Anxiety Agents; D014149:Tranquilizing Agents; D001569:Benzodiazepines