Some immunological mechanisms of the influenza virus antitumour effect.
Vaccine strains of influenza A virus inhibited the growth of ascitic tumour cells and outbred rats or inbred mice. The infected tumour bearers had an enhanced immune response to viral and specific tumour antigens. These phenomena are apparently due to the formation of complexes of both antigens on cell membranes and increased immunogenicity of such complexes.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000096:biosynthesis; D000914:Antibodies, Viral / Q000096:biosynthesis; D002462:Cell Membrane / Q000276:immunology; D005260:Female; D009980:Influenza A virus / Q000187:drug effects / Q000276:immunology*; D007252:Influenza Vaccines; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology*; D010051:Ovarian Neoplasms / Q000276:immunology*; D011420:Propiolactone / Q000494:pharmacology; D051381:Rats
D000912:Antibodies, Neoplasm; D000914:Antibodies, Viral; D007252:Influenza Vaccines; D011420:Propiolactone