[Effect of H+ and OH- ions on the physiological and biochemical properties of a Pseudomonas methanolica culture].
The growth of Pseudomonas methanolica was inhibited by unfavourable values of pH in the conditions of chemostat; the rate of the substrate assimilation was higher, and anabolic and catabolic reactions were decoupled. Hydrogen ions inhibited the activity of enzymes of the Krebs cycle, hydroxyl ions inhibited the activity of methanol dehydrogenase. Changes in pH are presumed to involve the energy apparatus of the cell membrane.
D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors; D002414:Cations, Monovalent; D002952:Citric Acid Cycle / Q000187:drug effects; D003470:Culture Media; D004734:Energy Metabolism / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D006128:Growth / Q000187:drug effects; D006859:Hydrogen / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D006900:Hydroxylation; D000432:Methanol / Q000378:metabolism; D011549:Pseudomonas / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism
D002414:Cations, Monovalent; D003470:Culture Media; D006859:Hydrogen; D000429:Alcohol Oxidoreductases; D000432:Methanol
Vliianie ionov H+ i OH- na fiziologo-biokhimicheskie svoĭstva kul'tury Pseudomonas methanolica