The use of chlorazepate for premedication on the night before surgery.
Chlorazepate, a long-acting benzodiazepine, allayed anxiety before operation, being superior to placebo in a double-blind study in which the drug was given the night before surgery. Long-term relief of apprehension before surgery by the administration of chlorazepate, combined with a narcotic analgesic when indicated, is advocated.
D000328:Adult; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001007:Anxiety / Q000187:drug effects; D002986:Clinical Trials as Topic; D003009:Clorazepate Dipotassium / Q000494:pharmacology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D011292:Premedication; D013997:Time Factors
D014151:Anti-Anxiety Agents; D003009:Clorazepate Dipotassium