Kinetics of nitrosation of the herbicide glyphosate.
The herbicide glyphosate was nitrosated by third-order kinetics to N-nitrosoglyphosate. The nitrosation at 25 degrees C was maximum at the reaction pH of 2.5 and had a pH-dependent rate constant of 2.43 M-2 sec-1. An activation energy of 9.5 kcal mole-1 also suggested that glyphosate is nitrosated very readily. Thiocyanate increased the rate 4.6 fold. The possibility of using these results to predict the formation of N-nitrosoglyphosate under normal agricultural practice is discussed.
D055598:Chemical Phenomena; D002621:Chemistry; D005998:Glycine / Q000031:analogs & derivatives*; D006540:Herbicides; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009573:Nitrites; D009602:Nitrosamines; D009943:Organophosphorus Compounds; D010573:Pesticide Residues; D013816:Thermodynamics; D013861:Thiocyanates; D000097797:Glyphosate
D005998:Glycine; D006540:Herbicides; D009573:Nitrites; D009602:Nitrosamines; D009943:Organophosphorus Compounds; D010573:Pesticide Residues; D013861:Thiocyanates; D000097797:Glyphosate