Effects of adrenergic blocking agents on lipolysis and adenyl cyclase activity induced by vasoactive intestinal polypeptide (VIP).
VIP stimulates lipolysis and adenyl cyclase activity in the rat adipose tissue. VIP-induced lipolysis and adenyl cyclase activity are not affected by phenoxybenzamine. VIP-induced lipolysis is inhibited by propranolol but VIP-induced adenyl cyclase activity is not.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000273:Adipose Tissue / Q000201:enzymology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D005768:Gastrointestinal Hormones / Q000494:pharmacology*; D050356:Lipid Metabolism; D008297:Male; D010643:Phenoxybenzamine / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D014660:Vasoactive Intestinal Peptide / Q000494:pharmacology*
D000319:Adrenergic beta-Antagonists; D005768:Gastrointestinal Hormones; D010643:Phenoxybenzamine; D014660:Vasoactive Intestinal Peptide; D011433:Propranolol; D000262:Adenylyl Cyclases