[Effects of diazepam and flunitrazepam on the undesired postoperative side-effects of ketamine anaesthesia (author's transl)].
150 patients undergoing minor gynaecological procedures (curretages) were anesthetized with ketamine and either diazepam flunitrazepam or placebo in order to establish the best combination for the prevention of postoperative psychotomimetic effects. From observations, up to 24 h after operation, it was found and statistically proven that the combination of ketamine/flunitrazepam as compared to the combinations ketamine/diazepam and ketamine/placebo led to a remarkable reduction of psychotomimetic side reactions.
D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001007:Anxiety; D001285:Atropine; D003975:Diazepam / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005445:Flunitrazepam / Q000627:therapeutic use*; D006801:Humans; D007649:Ketamine; D008875:Middle Aged; D010919:Placebos; D011292:Premedication
D014151:Anti-Anxiety Agents; D010919:Placebos; D005445:Flunitrazepam; D007649:Ketamine; D001285:Atropine; D003975:Diazepam
Möglichkeiten der medikamentösen Beeinflussung von unerwünschten Nebenwirkungen und Aufwachreaktionen nach Ketamin-Anaesthesie.