[The hypertrophic obstructive cardiomyopathy (HOCM) of the newborn].
A case of a newborn infant with clinical and angiocardiographic signs of hypertrophic obstructive cardiomyopathy (HOCM) is presented. The baby died after a short therapy with beta-blockers. Light- and electron-microscopic investigations showed severe disorganization of muscular cellular arrangement and disturbances of intracellular structures of the interventricular septum. HOCM is a genetically determined disease which can present clinically in the newborn period and may simulate congenital cardiac malformations.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D002312:Cardiomyopathy, Hypertrophic / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology*; D008297:Male; D008929:Mitochondria, Heart; D009206:Myocardium / Q000648:ultrastructure
D000319:Adrenergic beta-Antagonists
Die hypertrophische obstruktive Kardiomyopathie (HOCM) des Neugeborenen.