Studies on new process procedures in plasma fractionation on an industrial scale. II. Experiments in concentrating dilute albumin solutions using hollow fiber ultrafiltration.
Ultrafiltration with a hollow fiber device was studied as an alternative method to the lyophilization or thin-layer distillation techniques in the production of salt-poor, concentrated human albumin preparations for clinical use. A number of process parameters are discussed. Combination of gel filtration and ultrafiltration provides an interesting alternative to the currently used systems.
D005591:Chemical Fractionation / Q000379:methods; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010949:Plasma; D012709:Serum Albumin; D012996:Solutions; D013242:Sterilization; D013696:Temperature; D014462:Ultrafiltration / Q000379:methods
D012709:Serum Albumin; D012996:Solutions