The synthesis and urinary estimation of N-hydroxyaprobarbitone.
N-Hydroxyaprobarbitone (I) has been synthesized by oxidation of aprobarbitone, characterized, and a method developed for its estimation in urine. It has shown to be no more than a minor metabolite (less than 4%) in the human metabolism of aprobarbitone.
D001463:Barbiturates / Q000138:chemical synthesis* / Q000652:urine; D001711:Biotransformation; D006801:Humans; D008297:Male
D001463:Barbiturates