Regulation of guanylate and adenylate cyclase activities by lysolecithin.
The guanylate cyclase activity [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] in membrane preparations from 3T3 mouse fibroblasts is stimulated approximately 5-fold by lysolecithin at concentrations of 100 mug/ml and above.
D000067956:Adenylyl Cyclase Inhibitors; D002460:Cell Line; D002462:Cell Membrane / Q000201:enzymology; D002471:Cell Transformation, Neoplastic; D005459:Fluorides / Q000494:pharmacology; D006162:Guanylate Cyclase / Q000378:metabolism*; D008055:Lipids / Q000494:pharmacology; D008244:Lysophosphatidylcholines / Q000031:analogs & derivatives / Q000494:pharmacology*; D011092:Polyethylene Glycols / Q000494:pharmacology
D000067956:Adenylyl Cyclase Inhibitors; D008055:Lipids; D008244:Lysophosphatidylcholines; D011092:Polyethylene Glycols; D006162:Guanylate Cyclase; D005459:Fluorides