Sipple's syndrome. A urologist's viewpoint.
A case of Sipple's syndrome, a triad of medullary carcinoma of the thyroid, pheochromocytoma, and parathyroid hyperplasia is presented. The cause, laboratory diagnosis, and operative management of the syndrome are discussed. The need for thorough endocrine screening of patients with pheochromocytoma and family screening of patients with the full syndrome is stressed.
D002277:Carcinoma / Q000235:genetics; D006801:Humans; D006965:Hyperplasia; D007669:Kidney Calculi / Q000150:complications; D008297:Male; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia; D009378:Neoplasms, Multiple Primary / Q000235:genetics; D010280:Parathyroid Glands / Q000473:pathology*; D010673:Pheochromocytoma / Q000150:complications / Q000235:genetics / Q000601:surgery; D013577:Syndrome; D013964:Thyroid Neoplasms / Q000235:genetics