[Stability of tetracycline during fermentation].
The stability of tetracycline was studied at pH 6.0 and 1.5. The thermal inactivation constant at the lower pH was found to vary between 1.62 min-1 (40 degrees C) and 65.83 min-1 (100 degrees C). A degradation mechanism was proposed in the light of the variation of entropy and steric factors.
D004355:Drug Stability; D005285:Fermentation; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008433:Mathematics; D013752:Tetracycline
D013752:Tetracycline
Estabilidade da tetraciclina em meio de fermentação.