Effect of capsule colour and order of administration of hypnotic treatments.
Ninety-six hospitalized insomniac patients were asked to compare by a daily questionnaire the effect on sleep of the colour of the capsules and the order of administration of two treatments--heptabarbital and placebo. A balanced incomplete-block design was used; sleep onset time and sleep duration time were the main criteria of assessment. There was a significant interaction of colour and order of administration with sex. The placebo response was positive in 36% of instances.
D001463:Barbiturates / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology; D002214:Capsules; D002986:Clinical Trials as Topic; D003116:Color; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D010919:Placebos; D012107:Research Design; D012737:Sex Factors; D012890:Sleep / Q000187:drug effects*; D013997:Time Factors
D001463:Barbiturates; D002214:Capsules; D006993:Hypnotics and Sedatives; D010919:Placebos