Beta-adrenergic blocking agents as potent antagonists of mescaline-induced contractions in the rat uterus.
In the isolated rat uterus, mescaline induces contractions that are notably antagonized by catecholamines, by beta-adrenergic stimulants and certain beta-adrenergic blocking agents as well as by chlorpromazine, amitriptyline and methysergide.
D000318:Adrenergic beta-Agonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000639:Amitriptyline / Q000494:pharmacology; D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology; D005260:Female; D066298:In Vitro Techniques; D008635:Mescaline / Q000037:antagonists & inhibitors*; D009119:Muscle Contraction / Q000187:drug effects*; D051381:Rats; D011955:Receptors, Drug; D014599:Uterus / Q000187:drug effects
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D011955:Receptors, Drug; D000639:Amitriptyline; D008635:Mescaline; D002746:Chlorpromazine