The coacervate-sol transition observed with alpha-elastin and its N-formyl O-methyl derivative.
The coacervate phase produced by raising the temperature of solutions of blocked alpha-elastin has water content and fibrillar structure at electron microscope level similar to fibrous elastin (Cox, B.A., Starcher, B.C., Urry, D.W. (1973) Biochim, Biophys. Acta 317, 209-213). The stability ranges of the coacervates under varying conditions of temperature, pH, salt concentration and concentration of added organic solvent have been investigated with results that suggest a marked sensitivity of elastin conformation to solution conditions.
D004549:Elastin; D005026:Ethylene Glycols / Q000494:pharmacology; D005561:Formates; D006863:Hydrogen-Ion Concentration; D008745:Methylation; D012965:Sodium Chloride / Q000494:pharmacology; D012995:Solubility; D013329:Structure-Activity Relationship; D013696:Temperature
D005026:Ethylene Glycols; D005561:Formates; D012965:Sodium Chloride; D004549:Elastin