Metabolic effects of beta-adrenoreceptor blockers.
The effects of beta-blockade on glucose metabolism are complex. Some patients with impaired glucose tolerance while taking a non-selective beta-blocker, showed some improvement in glucose tolerance when therapy was changed to a beta1-blocker (metoprolol). Serum K+ values tend to rise slightly on beta-blocking therapy; small increases in serum urea and creatinine also occur. A rise in plasma triglycerides was noted in patients starting beta-blocking therapy; this effect seemed to be more marked on metoprolol than on non-selective beta-blockers.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D001798:Blood Proteins / Q000378:metabolism; D002245:Carbon Dioxide / Q000097:blood; D003404:Creatinine / Q000097:blood; D005947:Glucose / Q000378:metabolism; D005951:Glucose Tolerance Test; D006801:Humans; D008055:Lipids / Q000097:blood; D011188:Potassium / Q000097:blood; D012083:Renin / Q000097:blood; D014508:Urea / Q000097:blood
D000319:Adrenergic beta-Antagonists; D001798:Blood Proteins; D008055:Lipids; D002245:Carbon Dioxide; D014508:Urea; D003404:Creatinine; D012083:Renin; D005947:Glucose; D011188:Potassium