Drug oxidations dependent on cytochrome P-450 in isolated hepatocytes. The role of the tricarboxylates and the aminotransferases in NADPH supply.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000625:Aminooxyacetic Acid / Q000494:pharmacology; D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000818:Animals; D003523:Cycloserine / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003600:Cytosol / Q000378:metabolism; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D008954:Models, Biological; D009249:NADP / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D000637:Transaminases / Q000378:metabolism*; D014233:Tricarboxylic Acids / Q000378:metabolism*
D014233:Tricarboxylic Acids; D000625:Aminooxyacetic Acid; D009249:NADP; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D003577:Cytochrome P-450 Enzyme System; D003523:Cycloserine; D006899:Mixed Function Oxygenases; D000633:Aminopyrine N-Demethylase; D000637:Transaminases; D010634:Phenobarbital