Mechanism of in vitro mutagenic activation and covalent binding of N-hydroxy-2-acetylaminofluorene in isolated liver cell nuclei from rat and mouse.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D002467:Cell Nucleus / Q000378:metabolism; D003543:Cysteamine / Q000494:pharmacology; D005449:Fluorenes / Q000378:metabolism*; D006881:Hydroxyacetylaminofluorene / Q000378:metabolism* / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009153:Mutagens / Q000378:metabolism*; D009249:NADP / Q000494:pharmacology; D009696:Nucleic Acids / Q000378:metabolism; D009698:Nucleoproteins / Q000378:metabolism; D010261:Paraoxon / Q000494:pharmacology; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects; D013347:Subcellular Fractions / Q000378:metabolism
D000975:Antioxidants; D005449:Fluorenes; D009153:Mutagens; D009696:Nucleic Acids; D009698:Nucleoproteins; D009249:NADP; D006881:Hydroxyacetylaminofluorene; D003543:Cysteamine; D010261:Paraoxon