Activation of sustained sympathetic vasodilatation in dog by spinal cord stimulation.
Electrical stimulation in lateral sites of the upper cervical spinal cord evoked vasodilatation after adrenergic blockade. Sympathetic fibres mediating sustained vasodilatation were shown to be separate from adrenergic sympathetic fibres since the adrenergic vasoconstrictor response in the paw evoked by vasomotor stimulation in the medulla was not reversed to vasodilatation after bretylium.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001920:Bradykinin / Q000494:pharmacology; D001949:Bretylium Compounds / Q000494:pharmacology; D002200:Capillary Resistance / Q000187:drug effects; D004285:Dogs; D004558:Electric Stimulation; D006614:Hindlimb; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D008526:Medulla Oblongata / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000502:physiology*
D001949:Bretylium Compounds; D006634:Histamine H1 Antagonists; D001285:Atropine; D006632:Histamine; D001920:Bradykinin