Irreversible blockade of the histamine response in depolarized smooth muscle.
D000818:Animals; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*; D010643:Phenoxybenzamine / Q000494:pharmacology; D011188:Potassium / Q000494:pharmacology*
D006634:Histamine H1 Antagonists; D010643:Phenoxybenzamine; D006632:Histamine; D011188:Potassium