[Ultrastructure of the parietal cells of the gastric mucosa in ulcer disease of the duodenum with a hyperacid syndrome (ultrastructurometric study)].
An electron-microscopy investigation and morphometric analysis were carried out in 30 specimens of bioptic material of the fundal part of the stomach in patients with duodenal ulcer with the hyperacid syndrome. At all levels of the Major gastric glands parietal cells with morphological signs of intensive secretory activity prevailed, which was one of the causes (apart from the increase in the mass of parietal cells) of considerable intensification of secretion of hydrochloric acid. It was suggested that a considerably increased (as compared with the norm) area of the surface of the crysts of mitochondria with simultaneous reduction of the coefficient of their fragmentation was the morphological substrate of a high functional activity of parietal cells of the gastric mucosa in the hyperacid syndrome.
D004381:Duodenal Ulcer / Q000473:pathology*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism / Q000648:ultrastructure*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006965:Hyperplasia; D008247:Lysosomes / Q000648:ultrastructure; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D013577:Syndrome
Ul'trastruktura obkladochnykh kletok slizistoĭ obolochki zheludka pri iazvennoĭ bolezni dvenadtsatiperstnoĭ kishki s giperatsidnym sindromom (ul'trastrukturometricheskoe issledovanie)