[Comparative action of toxins isolated from the venom of the scorpion (Androctonus australis) and the tentacles of the sea anemone (Anemonia Sulcata) on an isolated frog neuromuscular preparation].
We have shown that, if Scorpion venom is acting a skeletal muscle indirectly by releasing Acetycholine and directly by inducing an increase in intracellular free calcium, the main action of toxin II isolated from Anemonia Sulcata tentacles is presynaptic.
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D001001:Anura; D002118:Calcium / Q000494:pharmacology; D003064:Cnidarian Venoms / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D012604:Scorpion Venoms / Q000494:pharmacology*; D012615:Sea Anemones; D009435:Synaptic Transmission / Q000187:drug effects; D014403:Tubocurarine / Q000494:pharmacology
D003064:Cnidarian Venoms; D012604:Scorpion Venoms; D000109:Acetylcholine; D002118:Calcium; D014403:Tubocurarine
Action comparative des toxines isolées du venin Scorpion (Androctonus australis) et des tentacules d'Anémone de mer (Anemonia Sulcata) sur une préparation neuro-musculaire isolée de Grenouille.