Use of salazopyrin for prevention of peritoneal adhesions in rats.
The effect of orally administered salazopyrin on the prevention of experimentally induced peritoneal adhesions in albino rats was investigated. Comparison of the findings with those for untreated rats and rats given penicillin for sulfadiazine indicated that salazopyrin has a preventive effect on the development of peritoneal adhesions. This effect is dose dependent and does not seem to be due merely to the antibacterial effect of the drug.
D000818:Animals; D010406:Penicillins / Q000008:administration & dosage / Q000627:therapeutic use; D010532:Peritoneal Diseases / Q000517:prevention & control*; D051381:Rats; D013411:Sulfadiazine / Q000008:administration & dosage / Q000627:therapeutic use; D012460:Sulfasalazine / Q000627:therapeutic use*; D000267:Tissue Adhesions / Q000517:prevention & control
D010406:Penicillins; D013411:Sulfadiazine; D012460:Sulfasalazine