[Partial disorganization of the anaphasic segregation of chromosomes in plant cells: combined actions of griseofulvin, producer of pluripolar anaphases and 2 ipecac alkaloids, producers of floating pole anaphases].
Anaphasis may be slightly checked by various treatments which however result in a normal chromosomic separation. Griseofulvin exerts a direct though partial influence on the mitotic apparatus, which entails "pluripolar anaphasis"; on the other hand Ipecac alkaloïds act indirectly and produce "floating poles anaphases". Treatments combining griseofulvin with cepheline or tubulosine show that there is never any synergy between the two processes. These results support our hypothesis that floating poles anaphases are not a sign of slight C-mitotic action but only come from a lag between the appearance/disappearance of microtubules and that of chromosomes during anaphasis.
D000705:Anaphase / Q000187:drug effects*; D002453:Cell Cycle / Q000187:drug effects*; D005737:Garlic; D006118:Griseofulvin / Q000494:pharmacology*; D007486:Ipecac / Q000494:pharmacology*; D010944:Plants / Q000648:ultrastructure*; D010946:Plants, Medicinal
D006118:Griseofulvin; D007486:Ipecac
Désorganisation partielle de la ségrégation anaphasique des chromosomes dans la cellule végétale: actions combinées de la griséofulvine, productrice d'anaphases pluripolaires, et de deux alcaloïdes de l'ipéca, producteurs d'anaphases à pôles flottants.