[Gonadotropin induced steriodogenesis in prepubertal boys (author's transl)].
We examined the capacity of reaction in the endocrine tissue of testes in prepubertal boys. 18 boys were endocrinologically healthy, six suffered from cryptorchidism on one or both sides. After a single dose of HCG (5000 IU/m) we found an increase of pregnantriol excretion in the 24 h urine in all subjects studied except in the case of surgically proved anorchia. In all except one boy we found a sharp increase in testosterone after HCG administration.
D015068:17-Ketosteroids / Q000096:biosynthesis; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D006063:Chorionic Gonadotropin / Q000008:administration & dosage*; D003345:Corticosterone / Q000096:biosynthesis; D003456:Cryptorchidism / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D006908:Hydroxyprogesterones / Q000652:urine; D008297:Male; D011279:Pregnanetriol / Q000652:urine; D011627:Puberty; D013737:Testis / Q000187:drug effects* / Q000502:physiology / Q000503:physiopathology; D013739:Testosterone / Q000096:biosynthesis; D013997:Time Factors
D015068:17-Ketosteroids; D006063:Chorionic Gonadotropin; D006908:Hydroxyprogesterones; D011279:Pregnanetriol; D013739:Testosterone; D003345:Corticosterone
Gonadotropin-induzierte Steriodproduktion bei praepuberalen Knaben