Models for metal ion function in carbonic anhydrase.
A model catalyst is described which has properties in common with carbonic anhydrase. The model demonstrates the availability of a mechanism, previously only hypothetical, for the action of the enzyme. It also shows, however, that this mechanism alone is not adequate to produce the high activity of the enzyme.
D000079:Acetaldehyde; D002245:Carbon Dioxide; D002256:Carbonic Anhydrases / Q000378:metabolism*; D002384:Catalysis; D055598:Chemical Phenomena; D002621:Chemistry; D006863:Hydrogen-Ion Concentration; D006878:Hydroxides; D008024:Ligands; D008954:Models, Biological; D014867:Water; D015032:Zinc / Q000378:metabolism*
D006878:Hydroxides; D008024:Ligands; D014867:Water; D002245:Carbon Dioxide; D002256:Carbonic Anhydrases; D000079:Acetaldehyde; D015032:Zinc