Development of amino acid uptake activity in Neurospora.
During the germination and growth of Neurospora conidia, amino acid permease systems I (neutral) and II (general) increase in specific activity. System III (basic) decreases in specific activity with the onset of germination. System I shows two peaks of activity during the logarithmic phase of growth. One peak occurs at 6 h, the other at 12 h of growth. Both peaks are abolished in the mtr mutant. Both peaks have a Km for phenylalanine of 40 muM. The peaks of system I activity appear to correlate with morphological changes.
D000596:Amino Acids / Q000378:metabolism*; D001120:Arginine / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D026901:Membrane Transport Proteins / Q000378:metabolism; D009154:Mutation; D009491:Neurospora / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D010649:Phenylalanine / Q000378:metabolism; D000644:Quaternary Ammonium Compounds / Q000378:metabolism; D013172:Spores, Fungal / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism; D014364:Tryptophan / Q000031:analogs & derivatives / Q000378:metabolism
D000596:Amino Acids; D026901:Membrane Transport Proteins; D000644:Quaternary Ammonium Compounds; D010649:Phenylalanine; D014364:Tryptophan; D001120:Arginine; D005947:Glucose