Different behaviour of thymus in hosts bearing skin homografts or ehrlich ascites carcinoma.
Thymus behaviour in A2G male mice transplanted with skin homografts or Ehrlich ascites carcinoma was followed for a period of 28 days. In comparison with control mice of the same strain in which only a slowly physiological involution of the thymus was observed, a marked, irreversible involution was seen in the tumour-bearing mice in contrast with the transient, completely recovered involution in animals transplanted with skin homografts. Thymus behaviour appears as the major structural difference between a host developping a strongly efficient or an inefficient immune response.
D000818:Animals; D000912:Antibodies, Neoplasm; D000917:Antibody Formation; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology*; D006087:Graft vs Host Reaction; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D016038:Skin Transplantation; D013950:Thymus Gland / Q000276:immunology*; D014184:Transplantation, Homologous
D000912:Antibodies, Neoplasm