Effects of putative neurotransmitters on the motor activity of Spirometra mansonoides.
5-Hydroxytryptamine (5-HT), epinephrine, and dopamine strongly stimulated the motor activity of larval Spirometra mansonoides. By contrast, a cholinomimetic agent, arecoline, paralyzed the worms. There was some pharmacological specificity among the agonists but not with various antagonists. Acetylcholinesterase activity was present in both larval and adult Spirometra.
D000110:Acetylcholinesterase / Q000378:metabolism; D001115:Arecoline / Q000494:pharmacology; D002589:Cestoda / Q000502:physiology*; D004298:Dopamine / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects*; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D012701:Serotonin / Q000494:pharmacology; D013032:Sparganum / Q000502:physiology*
D018377:Neurotransmitter Agents; D012701:Serotonin; D001115:Arecoline; D000110:Acetylcholinesterase; D004298:Dopamine; D004837:Epinephrine