Redox modulation of splenic cell soluble guanylate cyclase activity: activation by hydrophilic and hydrophobic oxidants represented by ascorbic and dehydroascorbic acids, fatty acid hydroperoxides, and prostaglandin endoperoxides.
D000818:Animals; D001205:Ascorbic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology*; D003683:Dehydroascorbic Acid / Q000494:pharmacology*; D005227:Fatty Acids / Q000494:pharmacology; D006162:Guanylate Cyclase / Q000378:metabolism*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D010084:Oxidation-Reduction / Q000187:drug effects; D010545:Peroxides / Q000494:pharmacology*; D011449:Prostaglandin Endoperoxides / Q000494:pharmacology; D012995:Solubility; D013154:Spleen / Q000187:drug effects / Q000201:enzymology*; D014867:Water
D005227:Fatty Acids; D010545:Peroxides; D011449:Prostaglandin Endoperoxides; D014867:Water; D006162:Guanylate Cyclase; D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid