Intestinal brush border enzymes after short-term mesenteric ischemia.
The total activities of sucrase, trehalase, amino-peptidase, and gamma-glutamyltransferase in the isolated brush border of the entire small bowel are reduced to 35, 55, 33, and 21 per cent, respectively, of control values (p less than 0.001) 2 hours after a 45 minute occlusion of the superior mesenteric artery. Since brush border proteins are also reduced by ischemia to 42 per cent of control, enzymatic activity when expressed as U/mg protein is significantly reduced only in the case of gamma-glutamyltransferase, to 48 per cent of control.
D000818:Animals; D003250:Constriction; D007413:Intestinal Mucosa / Q000201:enzymology; D007421:Intestine, Small / Q000098:blood supply / Q000201:enzymology*; D007511:Ischemia / Q000201:enzymology / Q000209:etiology / Q000378:metabolism; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D008297:Male; D008638:Mesenteric Arteries; D051381:Rats; D013393:Sucrase / Q000378:metabolism; D014198:Trehalase / Q000378:metabolism; D005723:gamma-Glutamyltransferase / Q000378:metabolism
D005723:gamma-Glutamyltransferase; D014198:Trehalase; D013393:Sucrase; D007931:Leucyl Aminopeptidase