Amino-acid sequence of toxin I from Anemonia sulcata.
Toxin I from Anemonia sulcata, a major component of the sea anemone venom, consists of 46 amino acid residues which are linked by three disulfide bridges. The [14C]carboxymethylated polypeptide was sequenced to position 29 by automated Edman degradation. The remaining sequence was determined from cyanogen bromide peptides and from tryptic peptides of the citraconylated [14C]carboxymethylated toxin. Toxin I is homologous to toxin II from Anemonia sulcata and to anthopleurin A, a toxin from the sea anemone Anthopleura xanthogrammica. These toxins constitute a new class of polypeptide toxins. No significant homologies exist with toxin III from Anemonia sulcata nor with known sequences of neurotoxins or cardiotoxins of various origin.
D000595:Amino Acid Sequence; D000818:Animals; D003063:Cnidaria; D003064:Cnidarian Venoms; D010446:Peptide Fragments / Q000032:analysis; D012615:Sea Anemones; D013045:Species Specificity
D003064:Cnidarian Venoms; D010446:Peptide Fragments