[Effect of methionine sulfone on the growth of Citrobacter intermedius C3 (author's transl)].
Specific activity of glutamate dehydrogenase (GD) and glutamate synthase (GtS) has been determined in the wild strain C3 and on a non excreting pro- mutant strain. Methionine sulfone shows inhibitory effects on their growth. The addition of alpha-ketoglutarate to the medium prevents the inhibitory effect and increases the GtS specific activity in both strains. The physiological effect of methionine sulfone and its suppression by alpha-ketoglutarate is discussed.
D000818:Animals; D002954:Citrobacter / Q000254:growth & development*; D004755:Enterobacteriaceae / Q000254:growth & development*; D005969:Glutamate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005974:Glutamate-Ammonia Ligase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008715:Methionine / Q000494:pharmacology*
D008715:Methionine; D005969:Glutamate Dehydrogenase; D005974:Glutamate-Ammonia Ligase
Efecto de la metionín sulfona sobre el crecimiento de Citrobacter intermedius C3.