[Glucose transport across the mucosa of the small intestine].
The rate of glucose absorption in an isolated loop of the small intestine in rats was measured. The maximum rate of absorption was registered with 3 and 5 per cent concentrations, while 1 and 10 per cent solutions are absorbed at a slower rate. The absorption rate of 5 per cent glucose solution did not materially change for one hour after a sugar load. The small intestine mucosa transports glucose from a 5 per cent solution at an equal rate in rats and rabbits, i. e. 139+/-4 and 143+/-6 gamma/cm2/min. Maximum absorption takes place with pH of 6-8. Deviation of the pH value to acidity and alkalinity is attended by steep fall in the absorption rate. At pH of 3.0 and 11.5 the absorption virtually ceases altogether. Hexobarbital anesthesia depresses absorption of glucose in the intestine by a factor of 2-3.5.
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D005947:Glucose / Q000378:metabolism*; D006591:Hexobarbital / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007328:Insulin / Q000494:pharmacology; D007408:Intestinal Absorption / Q000187:drug effects; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism*; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D013997:Time Factors
D007328:Insulin; D006591:Hexobarbital; D005947:Glucose
O transporte gliukozy cherez slizistuiu obolochku tonkogo kishechnika