Metabolism of lergotrile to 13-hydroxy lergotrile, a potent inhibitor of prolactin release in vitro.
D000818:Animals; D003864:Depression, Chemical; D004873:Ergolines / Q000378:metabolism* / Q000494:pharmacology; D006168:Guinea Pigs; D006900:Hydroxylation; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism; D011388:Prolactin / Q000378:metabolism*
D004873:Ergolines; D011388:Prolactin