Diagnosis of renal tumor by gamma-glutamyltranspeptidase (EC 2.3.2.2).
A urinary enzyme pattern and kidney tissue pattern were investigated simultaneously in 117 urologic patients. In contrast to all other renal disorders only the sixteen malignant tumors of the kidney showed a significant drop of gamma-GT in tumor tissue and urine. So far urinary enzymology has been used only as screening test. Measurement of gamma-GT in urine, however, permits the diagnosis of kidney tumors.
D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000652:urine; D007770:L-Lactate Dehydrogenase / Q000378:metabolism / Q000652:urine; D005723:gamma-Glutamyltransferase / Q000378:metabolism / Q000652:urine*
D007770:L-Lactate Dehydrogenase; D005723:gamma-Glutamyltransferase