[Galenic studies of a new gastrotherapeutic drug].
This paper presents the methods for galenical investigations of a new gastrotherapeutic preparation. The results and their possible relations to therapy are discussed. The preparation is presented a press-coated tablet. Its antacid characteristics concerning the rate of effectiveness, potency and duration are compared with leading brands on the German market. Pepsin inactivation together with the rapid liberation of the spasmolytic agent propantheline and the psychically stabilising agent peranzine are demonstrated. The results of the stability tests for the active ingredients and the in vitro availability are described. The new product is a gastrotherapeutic preparation, which fulfils all requirements for rapid action and reliable therapy.
D000536:Aluminum Hydroxide / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D004355:Drug Stability; D005767:Gastrointestinal Diseases / Q000188:drug therapy*; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use; D010464:Perazine / Q000627:therapeutic use*; D011413:Propantheline / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D004338:Drug Combinations; D011413:Propantheline; D000536:Aluminum Hydroxide; D010464:Perazine; D008274:Magnesium
Ergebnisse der galenischen Prüfung eines neuen Gastrotherapeutikums