[Action of copper ions and of unfavorable medium pH values on protein and RNA synthesis by Candida utilis cells].
The effect of copper ions and unfavourable pH values of the medium on the incorporation of labelled precursors of protein and RNA was studied in Candida utilis. Specific inhibition of protein synthesis by copper ions and alkaline conditions was found. No specific inhibition of protein or RNA was detected at low pH values of the medium.
D002175:Candida / Q000187:drug effects* / Q000378:metabolism; D003300:Copper / Q000494:pharmacology*; D003470:Culture Media / Q000494:pharmacology*; D005656:Fungal Proteins / Q000096:biosynthesis*; D006863:Hydrogen-Ion Concentration; D007477:Ions; D007930:Leucine / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis*; D014498:Uracil / Q000378:metabolism
D003470:Culture Media; D005656:Fungal Proteins; D007477:Ions; D014498:Uracil; D012313:RNA; D003300:Copper; D007930:Leucine
Deĭstvie ionov medi i neblagopriiatnykh znacheniĭ pH sredy na sintez belka i RNK kletkami Candida utilis.