Cardiac output response to altered acid-base status during diethyl ether anaesthesia.
The effects of acid-base changes on cardiac output during diethyl ether anaesthesia were studied in 25 mongrel dogs prepared by surgically implanting a plastic encased non-ferrous core electromagnetic probe on the ascending aorta. The findings are: (1) Metabolic acidaemia produced only slight decrease in cardiac output but a more marked fall became evident with decreasing pH(2) Respiratory acidaemia led to a slight rise in cardiac output. (3) Respiratory alkalaemia decreased cardiac output. (4) Metabolic alkalaemia also produced a decline in cardiac output.
D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000097:blood / Q000139:chemically induced; D000142:Acidosis, Respiratory / Q000097:blood / Q000139:chemically induced; D000471:Alkalosis / Q000097:blood / Q000139:chemically induced; D000472:Alkalosis, Respiratory / Q000097:blood; D000769:Anesthesia, Inhalation; D000818:Animals; D001639:Bicarbonates; D001769:Blood; D002245:Carbon Dioxide / Q000097:blood; D002302:Cardiac Output; D004285:Dogs; D004986:Ether; D005019:Ethyl Ethers; D006851:Hydrochloric Acid; D006863:Hydrogen-Ion Concentration; D000860:Hypoxia / Q000097:blood; D008297:Male; D010100:Oxygen / Q000097:blood
D001639:Bicarbonates; D005019:Ethyl Ethers; D004986:Ether; D002245:Carbon Dioxide; D006851:Hydrochloric Acid; D010100:Oxygen