Natural history and classification of occlusive thromboaortopathy (Takayasu's disease).
Fifty-four Japanese patients with occlusive thromboaortopathy (OTAP), including four males, were classified according to evidence of complications attributed to OTAP at the time when the diagnosis was established: Group I, uncomplicated OTAP with or without the involvement of the pulmonary artery. Group II, mono-complicated OTAP: presence of a single complication together with uncomplicated OTAP. Group II was subdivided according to severity into group IIa - mild or moderate form, and group IIb - severe form. Group III, multi-complicated OTAP with two or more complications as well as uncomplicated OTAP. The five-year survival rate after established diagnosis was 83.1%. Seven patients died of OTAP within five years, but all had belonged to group IIb or III.
D000328:Adult; D000783:Aneurysm / Q000209:etiology; D001015:Aortic Arch Syndromes / Q000473:pathology*; D001022:Aortic Valve Insufficiency / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000209:etiology; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D006976:Hypertension, Pulmonary / Q000209:etiology; D008297:Male; D012164:Retinal Diseases / Q000209:etiology; D013625:Takayasu Arteritis / Q000145:classification / Q000473:pathology*