The influence of drug-induced alterations in the pressor-inotropic state on left ventricular dynamics.
These experiments present new data, obtained by direct measurement, describing the influence of Phe, NE, and ISO on ventricular MF or load. Measurement of MF along with measurements of ventricular pressure, size, and inotropic state allows for a more complete and meaningful characterization of the response of the intact ventricle to pharmacological interventions.
D000322:Adrenergic Agonists / Q000494:pharmacology*; D000818:Animals; D004285:Dogs; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles / Q000187:drug effects; D007545:Isoproterenol / Q000494:pharmacology; D009200:Myocardial Contraction / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D010656:Phenylephrine / Q000494:pharmacology; D011312:Pressure
D000322:Adrenergic Agonists; D010656:Phenylephrine; D007545:Isoproterenol; D009638:Norepinephrine; D010646:Phentolamine