Granulomatous hepatitis associated with salicylazosulfapyridine therapy.
Granulomatous hepatitis has been associated with many conditions, including chronic ulcerative colitis and sulfonamide therapy. We report a patient with ulcerative colitis in whom hepatic granulomatosis was associated with salicylazosulfapyridine (Azulfidine). Sulfonamides should be considered a possible cause of hepatotoxicity when used therapeutically in inflammatory bowel disease.
D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003093:Colitis, Ulcerative / Q000188:drug therapy; D005260:Female; D006099:Granuloma / Q000139:chemically induced*; D006801:Humans; D012460:Sulfasalazine / Q000009:adverse effects* / Q000627:therapeutic use
D012460:Sulfasalazine