[Glycosyltranferases. Biological and pathological importance].
Catalysing the transfer of oses and ose derivatives on various accepters, glucosyltransferases are of increasing importance in biology and pathology. Their sub-cellular localisation is now known together with the physico-chemical parameters of their activity and the importance of polyprenic intermediates. The first phenomenological studies concerning them are in favour of a mechanism of Bi-Bi type. For example, they may play a role in mucoviscidosis, virus diseases, vaccination and arthrosis.
D000818:Animals; D003550:Cystic Fibrosis / Q000201:enzymology; D004286:Dolichols / Q000378:metabolism; D005110:Extracellular Space / Q000201:enzymology; D006023:Glycoproteins / Q000096:biosynthesis; D006602:Hexosyltransferases / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007251:Influenza, Human / Q000201:enzymology; D007424:Intracellular Fluid / Q000201:enzymology; D007527:Isoenzymes / Q000032:analysis; D008861:Microsomes / Q000201:enzymology; D009702:Nucleoside Diphosphate Sugars / Q000378:metabolism; D009844:Oligosaccharides / Q000378:metabolism; D010003:Osteoarthritis / Q000201:enzymology; D013329:Structure-Activity Relationship; D013347:Subcellular Fractions / Q000201:enzymology; D014612:Vaccines / Q000494:pharmacology
D004286:Dolichols; D006023:Glycoproteins; D007527:Isoenzymes; D009702:Nucleoside Diphosphate Sugars; D009844:Oligosaccharides; D014612:Vaccines; D006602:Hexosyltransferases
Les glycosyltransférases. Importance biologique et pathologique