Lesion-induced synaptogenesis in brain: a study of dynamic changes in neuronal membrane specializations.
When incoming fibers to a given brain region are damaged and degenerate, the remaining undamaged fibers can, in some cases, form new synapses, and restore physiologically functional circuitry. Synaptic membrane events underlie this reconstruction: the connection between membranes is broken and reformed.
D000818:Animals; D001921:Brain / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology / Q000648:ultrastructure; D003714:Denervation; D005643:Fucose / Q000032:analysis; D005688:Galactosamine / Q000032:analysis; D005690:Galactose / Q000032:analysis; D005944:Glucosamine / Q000032:analysis; D006595:Hexosamines / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D008358:Mannose / Q000032:analysis; D008954:Models, Biological; D009474:Neurons / Q000502:physiology*; D012794:Sialic Acids / Q000032:analysis; D013569:Synapses / Q000032:analysis / Q000502:physiology* / Q000648:ultrastructure
D006595:Hexosamines; D012794:Sialic Acids; D005643:Fucose; D005688:Galactosamine; D005944:Glucosamine; D008358:Mannose; D005690:Galactose