[A study of allergy to local anesthetics using the lymphoblast transformation test].
The lymphocyte transformation test (LTT) confirms the classical concept that Novocain is three times as potent as Xylocaine as a sensitizing agent. This sensitization to Novocaine is more common in patients with an allergic constitution and in those treated with several drugs. The LTT made it possible to identify the responsible drug, which was not always a local anesthetic, but sometimes Penicillin G and aspirin.
D000328:Adult; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000276:immunology; D055598:Chemical Phenomena; D002621:Chemistry; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D011343:Procaine / Q000276:immunology
D000779:Anesthetics, Local; D011343:Procaine; D008012:Lidocaine
Etude de l'allergie aux anesthĕsiques locaux par test de transformation lymphoblastique