[Metabolism of nitrates-nitrites].
Once the pair nitrate-nitrite--in quantity respectively set by the ingestion level or transformation level by intestinal bacteria--has entered through the intestinal mucosa, it may react with active biochemical groups. Nitrite, owing to its high oxido-reduction potential, may induce the oxidation of a large number of compounds, as for example the Fe++ heme-Fe+++ hemine system, reduced cytochromes-oxidized cytochromes system, etc. If the presence of nitrite in blood is not clearly established, this is due to the nitrite high chemical reactivity. Moreover, a transformation by the tissues of nitrates into nitrites after a nitro-reduction is quite possible.
D000588:Amines / Q000378:metabolism; D000818:Animals; D003580:Cytochromes / Q000378:metabolism; D006418:Heme / Q000378:metabolism; D006427:Hemin / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007413:Intestinal Mucosa / Q000502:physiology; D007422:Intestines / Q000382:microbiology / Q000502:physiology*; D009566:Nitrates / Q000378:metabolism* / Q000633:toxicity; D009573:Nitrites / Q000378:metabolism* / Q000633:toxicity; D010084:Oxidation-Reduction
D000588:Amines; D003580:Cytochromes; D009566:Nitrates; D009573:Nitrites; D006418:Heme; D006427:Hemin
Métabolisme des nitrates-nitrites.