Effects of prolonged administration of high molecular levan on arterial blood gases, oxygen transport and acid base balance in rabbits.
The effect of daily intraperitoneal injections of 100 mg of high molecular levan for 4-6 weeks on a number of physiological parameters was studied in rabbits. The parameters studied included whole blood pH, blood gases and acid-base balance. Control rabbits were similarly treated with physiological saline. In five rabbits T-50 was determined after levan treatment. None of the studied parameters was significantly affected by the levan treatment.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000818:Animals; D001639:Bicarbonates / Q000097:blood; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D005630:Fructans / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008297:Male; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000378:metabolism; D011134:Polysaccharides / Q000494:pharmacology*; D011817:Rabbits
D001639:Bicarbonates; D005630:Fructans; D010108:Oxyhemoglobins; D011134:Polysaccharides; D002245:Carbon Dioxide; D010100:Oxygen