Mutagenic and recombinogenic action of pesticides in Aspergillus nidulans.
Thirteen pesticides, aminotriazole, benomyl, captafol, captan, dalapon-Na, dichlorvos, dinobuton, dodine, ioxynil, mecoprop, neburon, picloram and tordon were tested for ability to induce (1) point mutations to 8-azaguanine resistance, (2) mitotic crossing-over, and (3) mitotic non-disjunction and haploidization in Aspergillus nidulans. Tests were performed at three different pHs, i.e. 4.5, 7, 8.2. Three of the pesticides, captan , captafol and dichlorvos induced point mutations; dichlorvos also induced a high frequency of mitotic crossing-over and non-disjunction; benomyl induced a very high frequency of non-disjunction whereas aminotriazole induced weakly both types of somatic segregation.
D001233:Aspergillus nidulans / Q000235:genetics; D003434:Crossing Over, Genetic; D005821:Genetic Techniques; D006863:Hydrogen-Ion Concentration; D009153:Mutagens; D009154:Mutation; D010575:Pesticides / Q000494:pharmacology*; D011995:Recombination, Genetic
D009153:Mutagens; D010575:Pesticides