Kinetics and biochemical properties of haemopoietic stem cells during chicken development.
Haemopoietic stem cells from donors of different ages (embryos, adults) have been grafted into irradiated hosts. Cell multiplication kinetics, foetal haemoglobin production, age-specific antigen production were examined during two weeks after grafting. The results obtained tend to show that the erythrocyte characteristics are, for a large part, already determined in a stem cell type endowed with a large proliferative capacity.
D000367:Age Factors; D000740:Anemia / Q000503:physiopathology; D000818:Animals; D000941:Antigens; D001853:Bone Marrow / Q000378:metabolism; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D004912:Erythrocytes / Q000276:immunology; D004920:Erythropoiesis; D005260:Female; D005319:Fetal Hemoglobin / Q000096:biosynthesis; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000378:metabolism; D008954:Models, Biological; D011828:Radiation Chimera; D014817:Vitelline Membrane / Q000166:cytology / Q000378:metabolism
D000941:Antigens; D005319:Fetal Hemoglobin