[Ethological analysis of the action of medazepam and diazepam on the zoosocial behavior of isolated mice].
Tests set up with isolated mice of two groups (aggressive and "fearful") evidenced that diazepam and medazepam weaken the behavioral manifestations of the partner's avoidance, increase sociability in "fearful" mice and help to regain the ability for elementary intraspecies contacts. These drugs have a biphasic action on the behavior of aggressive mice, small doses (medazepam 0.1 mg/kg) facilitating aggression and large one (medazepam, diazepam--5 mg/kg) suppressing it.
D000374:Aggression / Q000187:drug effects; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects*; D003975:Diazepam / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005239:Fear / Q000187:drug effects; D006801:Humans; D008297:Male; D008472:Medazepam / Q000494:pharmacology*; D051379:Mice; D012919:Social Behavior; D012934:Social Isolation; D013997:Time Factors
D014151:Anti-Anxiety Agents; D008472:Medazepam; D003975:Diazepam
Etologicheskiĭ analiz deistviia medazepama i diazepama na zoosotsial'noe povedenie izolirovannykh mysheĭ.