Evidence against the participation of the gamma-glutamyltransferase-gamma-glutamylcylclotransferase pathway in amino acid transport by rabbit erythrocytes.
The GSH concentration of rabbit erythrocytes was monitored under conditions of large net transport of alanine, phenylalane and lysine in the absence of glucose. In no case was there an appreciable alteration in GSH concentration during amino acid uptake. It is suggested that the gamma-glutamyltransferase-gamma-glutamylcyclotransferase pathway does not participate in amino acid transport by these cells.
D000409:Alanine / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D004912:Erythrocytes / Q000378:metabolism; D005978:Glutathione / Q000032:analysis; D008239:Lysine / Q000378:metabolism; D010649:Phenylalanine / Q000378:metabolism; D011817:Rabbits; D005722:gamma-Glutamylcyclotransferase / Q000378:metabolism; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D000596:Amino Acids; D010649:Phenylalanine; D005723:gamma-Glutamyltransferase; D005722:gamma-Glutamylcyclotransferase; D005978:Glutathione; D008239:Lysine; D000409:Alanine