[Effect of the ionic environment and of various neurotransmitters on spontaneous motility in snail intestine (author's transl)].
A spontaneous rhythmic motility of the isolated intestine in snail, Chryptomphalus hortensis, has been registered at 30 degrees C with the aid of an electronic transductor and an appropriate amplification. These slow regular movements are affected by ionic composition changes in the suspension medium. Na+, K+ and Ca++ ions prove to be important in this motility, and the addition of Ba++ markedly stimulates it. ACh produces hypermotility from 1.8 X 10(-11) g/ml. Its effect decreases in the presence of atropine and increases in that of pyridostigmine. The intestine is sensitive to 5-HT from 10(-10) g/ml, which stimulates its activity. The effect of histamine is weak. Low concentrations of adrenaline tend to increase the amplitude, whereas concentrations from 10(-5) g/ml onward produce a cease of motility in relaxation.
D000818:Animals; D001464:Barium / Q000494:pharmacology; D004573:Electrolytes / Q000494:pharmacology*; D005769:Gastrointestinal Motility / Q000187:drug effects*; D007422:Intestines / Q000502:physiology; D007477:Ions; D008274:Magnesium / Q000494:pharmacology; D018377:Neurotransmitter Agents / Q000494:pharmacology; D009994:Osmolar Concentration; D012908:Snails / Q000502:physiology*; D013268:Stimulation, Chemical
D004573:Electrolytes; D007477:Ions; D018377:Neurotransmitter Agents; D001464:Barium; D008274:Magnesium
Efecto del ambiente iónico y sustancias neurotransmisoras sobre la motilidad espontánea del intestino del caracol (Cryptomphalus hortensis)