Separation and quantitative determination of acecarbromal, carbromal, and bromisoval as well as their main metabolites by means of high-pressure liquid chromatographic analysis.
A method is described to separate and quantitatively determine bromoureides and their bromo- and non-bromo-metabolites by means of high-pressure liquid chromatography. This method allows simultaneous measurement of these substances after intake of therapeutic as well as toxic doses.
D001968:Bromisovalum / Q000302:isolation & purification* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D006993:Hypnotics and Sedatives / Q000302:isolation & purification* / Q000378:metabolism; D013405:Suicide; D014508:Urea / Q000031:analogs & derivatives* / Q000302:isolation & purification* / Q000378:metabolism
D006993:Hypnotics and Sedatives; D001968:Bromisovalum; D014508:Urea