Cerebrospinal fluid acid-base status and lactate and pyruvate concentrations after short (less than 30 minutes) first febrile convulsions in children.
Twenty-nine infants and children with short (less than 30 minutes) first febrile convulsions were studied between 3 and 22 hours after convulsive episodes. Arterial and CSF acid-base variables, lactate and pyruvate concentrations, and lactate/pyruvate ratios were measured. Biochemical signs of cerebral hypoxia were found in only 2 patients, one of whom had short, repeated convulsions. Our findings indicate that hypoxic damage is unlikely to result from a short-duration febrile convulsion.
D000136:Acid-Base Equilibrium; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D002534:Hypoxia, Brain / Q000097:blood / Q000134:cerebrospinal fluid* / Q000209:etiology; D007223:Infant; D007773:Lactates / Q000134:cerebrospinal fluid*; D008297:Male; D011773:Pyruvates / Q000134:cerebrospinal fluid*; D012640:Seizures / Q000134:cerebrospinal fluid*; D003294:Seizures, Febrile / Q000097:blood / Q000134:cerebrospinal fluid* / Q000150:complications
D007773:Lactates; D011773:Pyruvates