Effect of caerulein on gamma-glutamyl transpeptidase and alkaline phosphatase in the duodenal juice in chronic pancreatitis.
During infusion of caerulein, the output of gamma-glutamyl transpeptidase and biliary alkaline phosphatase is significantly more increased in chronic pancreatitis patients than in normal subjects. The presence of the gall-bladder is necessary to observe this effect of caerulein. It is not related to the discharge of large amounts of both enzymes by the diseases pancreas.
D000469:Alkaline Phosphatase / Q000378:metabolism*; D002108:Ceruletide / Q000494:pharmacology*; D002908:Chronic Disease; D004386:Duodenum / Q000201:enzymology; D006801:Humans; D007419:Intestinal Secretions / Q000201:enzymology*; D010195:Pancreatitis / Q000201:enzymology*; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D002108:Ceruletide; D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase