Loss of activity of an N1-methyl-4-pyridone-5-carboxamide-forming N1-methylnicotinamide oxidase in livers of rats fed 2-acetylaminofluorene.
D015073:2-Acetylaminofluorene / Q000494:pharmacology*; D000445:Aldehyde Oxidoreductases / Q000302:isolation & purification / Q000378:metabolism*; D000818:Animals; D002848:Chromatography, DEAE-Cellulose; D005449:Fluorenes / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D009536:Niacinamide / Q000031:analogs & derivatives*; D051381:Rats; D013379:Substrate Specificity
D005449:Fluorenes; D009536:Niacinamide; D015073:2-Acetylaminofluorene; D000445:Aldehyde Oxidoreductases