A pH-dependent, carrier-mediated transport system for the folate analog, amethopterin, in rat jejunum.
D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology; D001693:Biological Transport, Active / Q000187:drug effects; D002852:Chromatography, Ion Exchange; D005947:Glucose / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects; D007583:Jejunum / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008727:Methotrexate / Q000031:analogs & derivatives / Q000378:metabolism* / Q000494:pharmacology; D009994:Osmolar Concentration; D051381:Rats; D013696:Temperature
D000963:Antimetabolites; D005947:Glucose; D008727:Methotrexate