An investigation into the deposition of inhalation aerosol particles as a function of air flow rate in a modified 'Kirk Lung'.
The effect of air flow rate on the deposition of inhalation aerosol particles in a modified 'Kirk Lung' has been studied. Two commercial products were used. The amount depositied in the mouthpiece and throat regions decreases with increasing flow rate. The amount in the collector rises to maximum of approximately 50%. This material represents the therapeutically available portion. Such an apparatus would be useful for routine quality control of the size distribution ratios for inhalation aerosol particles.
D000336:Aerosols; D000420:Albuterol / Q000008:administration & dosage; D002626:Chemistry, Pharmaceutical / Q000295:instrumentation; D007545:Isoproterenol / Q000008:administration & dosage; D008168:Lung; D012123:Pulmonary Ventilation
D000336:Aerosols; D007545:Isoproterenol; D000420:Albuterol