Cortisone sensitive T-cells in Peyers' patches.
Pretreatment of donor lymphoid cells with cortisone has been shown to depress the T-cell subpopulation responsible for cellular proliferation in the GVH reaction. A quantitative assay as well as the histological criteria of the GVH reaction have been used in this study to demonstrate the presence of cortisone-sensitive T-cells within the Peyer's patches as well as in the spleen and mesenteric lymph nodes in the rat.
D000818:Animals; D003348:Cortisone / Q000494:pharmacology*; D006087:Graft vs Host Reaction / Q000187:drug effects*; D008099:Liver / Q000166:cytology; D008221:Lymphoid Tissue / Q000166:cytology*; D010581:Peyer's Patches / Q000166:cytology* / Q000187:drug effects / Q000637:transplantation; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000166:cytology / Q000637:transplantation; D013601:T-Lymphocytes / Q000187:drug effects*; D013950:Thymus Gland / Q000166:cytology / Q000637:transplantation
D003348:Cortisone