[Immunosuppressive treatment in autoimmune vasculities].
From own experiences the observations of 3 patients were reported who were immunosuppressively treated with purine antagonists (azathioprine and 6-mercaptopurine). Hereby in a severe allergic vasculitis in a 22-year-old patient and in a granulomatous arteritis during Wegener's granulomatosis in a 51-year-old patient remissions for more than 1 and 7 years, respectively, could be achieved under immunosuppressive long-term therapy. In the case of a periarteriitis nodosa death took place 2 months after administration of 6-mercaptopurine.
D000328:Adult; D000368:Aged; D001167:Arteritis / Q000188:drug therapy; D001379:Azathioprine / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000188:drug therapy; D012075:Remission, Spontaneous; D013997:Time Factors; D014652:Vascular Diseases / Q000188:drug therapy* / Q000209:etiology
D007166:Immunosuppressive Agents; D015122:Mercaptopurine; D001379:Azathioprine
Immunsuppressive Therapie bei autoimmunbedingten Vaskulitiden