[Transfer electron and hydrogen atom in model and enzymatic reactions of NAD and NADP].
The paper deals with the mechanism of some model reactions of NAD and NADP which proceed with transfer of one electron and hydrogen atom. The joint oxidation of N-benzyl-1,4-dihydronicotinamide (I) and phenylglyoxal with hydrogen peroxide in the presence of cupric ions is found to result in transfer of one hydrogen atom from dihydropyridine molecule to hydroxy-radical and the electron to a molecule of oxygen or dinitrobenzene. The oxydation of I with benzoquinone is found to proceed with formation of free radicals as intermediate. The mechanism of NAD reduction with sodium hydrosulphite is proposed.
D055598:Chemical Phenomena; D002621:Chemistry; D003300:Copper; D004136:Dinitrobenzenes; D004579:Electron Transport; D005609:Free Radicals; D006037:Glyoxal / Q000031:analogs & derivatives; D006859:Hydrogen; D006861:Hydrogen Peroxide; D008956:Models, Chemical; D009243:NAD; D009249:NADP; D009536:Niacinamide / Q000031:analogs & derivatives; D010084:Oxidation-Reduction; D011809:Quinones
D004136:Dinitrobenzenes; D005609:Free Radicals; D011809:Quinones; D009243:NAD; D009536:Niacinamide; D006037:Glyoxal; D009249:NADP; D003300:Copper; D006859:Hydrogen; D006861:Hydrogen Peroxide
Perenos elektrona ĭ atoma vodniu v model'nikh i fermentativnikh reaktsiiakh NAD i NADF.