[Effect of different temperature fractions of RNA on allogenic inhibition of hematopoietic stem cells of mouse bone marrow and embryonal liver].
In the system of non-syngeneic transfer of stem hemopoietic cells, the preliminary incubation of the cells of bone marrow or embryonic liver of the C57BL mice with different temperature RNA fractions isolated from the spleen of (CBAXC57BL) F1 was shown to lead to the complete or partial restoration of the colony forming ability of the donor cells. The 63 degrees RNA fraction was shown to have the greatest restorative effect.
D000818:Animals; D001854:Bone Marrow Cells; D006084:Graft Rejection / Q000187:drug effects*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000187:drug effects; D006824:Hybridization, Genetic; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000196:embryology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D012313:RNA / Q000494:pharmacology*; D013696:Temperature; D014184:Transplantation, Homologous
D012313:RNA
Vliianie razlichnykh temperaturnykh fraktsiĭ RNK na allogennuiu ingibitsiiu stvolovykh krovetvornykh kletok kostnogo mozga i émbrional'noĭ pecheni mysheĭ.