Replication of swine and equine influenza viruses in canine kidney cells.
Both swine and equine influenza viruses were replicated in Madin-Darby canine kidney cells. Hemagglutinin and complement-fixing antigens were synthesized at 4 to 8 hours postinfection and reached maximal synthesis at 16 to 20 hours. Neuraminidase activity increased 9- to 11-fold; 50% of the total hemagglutinin antigen was made before the infective virus progeny was detected.
D000818:Animals; D000956:Antigens, Viral; D002478:Cells, Cultured; D004285:Dogs; D006736:Horses; D009980:Influenza A virus / Q000254:growth & development* / Q000276:immunology; D013552:Swine; D014779:Virus Replication
D000956:Antigens, Viral