[Use of phenazepam in the treatment of neurotic conditions].
The report contains data concerning clinical studies of a new Soviet tranquilizer of benzodiazepine derivative--phenazepam. Treatment of 100 patients gave a good therapeutical effect in 82%. The best results were attained in the treatment of generalized hystero-neurotical states, somewhat less in the group of neurotic states with a prevalence of affective disorders and the less effective in the obsessive-phobic syndrome. On the basis of comparative studies, the conclusion is made that phenazepam is not worse by its psychotropic activity than ativan (lorazepam) and exceeds diazepam (seduxen), most likely because of its myorelaxing action. The drug exerted an expressed hypnotic effect being not less than eunoctin and other eunectics.
D000328:Adult; D000342:Affective Symptoms / Q000188:drug therapy; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D001569:Benzodiazepines; D055598:Chemical Phenomena; D002621:Chemistry; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006998:Hypochondriasis / Q000188:drug therapy; D007046:Hysteria / Q000188:drug therapy; D008140:Lorazepam / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009497:Neurotic Disorders / Q000188:drug therapy*; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy; D010698:Phobic Disorders / Q000188:drug therapy; D012893:Sleep Wake Disorders / Q000188:drug therapy; D013577:Syndrome
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; C017928:phenazepam; D008140:Lorazepam; D003975:Diazepam
Primenenie fenazepama pri terapii nevroticheskikh sostoianiĭ.