[Effect of different factors on the rate of benzylpenicillin conversion in an aqueous system-butylacetate system].
It was shown that the mass-transfer coefficient of non-dissociated benzylpenicillin during extraction was more than 1000 times higher than that during reextraction. For the latter it was found that the aqueous phase exerted limiting resistance during mass-transfer of benzylpenicillin. The effect of a number of factors on the kinetics was shown. These factors were the following: hydrodynamic conditions, temperature, pH of the aqueous phase.
D000085:Acetates / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008433:Mathematics; D010400:Penicillin G / Q000302:isolation & purification / Q000494:pharmacology*; D012996:Solutions; D013678:Technology, Pharmaceutical / Q000295:instrumentation; D014867:Water / Q000494:pharmacology
D000085:Acetates; D012996:Solutions; D014867:Water; D010400:Penicillin G
Vliianie razlichnykh faktorov na skorost' perekhoda benzilpenitsillina v sisteme vodnaia sreda-butilatsetat