[Morphofunctional changes in the thymus of semisyngenous chimeras during the "graft versus host" response].
Activation of the enzymatic processes in the thymus cells was noted in the thymus gland at the early stages of the "transplantat-versus-host" reaction; the later stages were attended by inhibition of metabolic processes and reduction in number of immature and mature thymocytes in the cortical substance of the thymus. Besides, the cortical substance displayed accumulation of mesenchymal macrophages rich in lysosomal enzymes, particularly in the subcapsular layer where small foci of destruction formed at the late stages of the reaction.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D006087:Graft vs Host Reaction; D006651:Histocytochemistry; D006824:Hybridization, Genetic; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D008940:Mitotic Index; D010088:Oxidoreductases / Q000378:metabolism; D011828:Radiation Chimera; D013154:Spleen / Q000637:transplantation; D013950:Thymus Gland / Q000201:enzymology / Q000276:immunology* / Q000378:metabolism; D014184:Transplantation, Homologous
D010088:Oxidoreductases; D000135:Acid Phosphatase
Morfofunktsional'nye izmeneniia timusa polusingennykh khimer pri reaktsii "transplantat protiv khoziaina".