[The immediate effect of beta-isoket on the internal ocular pressure in patients with chronic simple glaucoma (author's transl)].
In 27 patients with non-compensated or medically compensated chronic simple glaucoma, the I.O.P. was measured after the administration of two tablets of beta-isoket (which contain 5 mg isosorbiddinitrate and 40 mg bupranolol). In none of the 54 eyes was the I.O.P. higher after administration of the drug. On the contrary, the I.O.P. was siginificantly or highly significantly reduced for more than 2 hours, probably because of the beta-receptor-blocking component of the preparation.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology* / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D002046:Bupranolol; D002908:Chronic Disease; D004338:Drug Combinations; D004341:Drug Evaluation; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D007548:Isosorbide Dinitrate / Q000494:pharmacology* / Q000627:therapeutic use; D008875:Middle Aged; D011412:Propanolamines / Q000494:pharmacology* / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D004338:Drug Combinations; D011412:Propanolamines; C011882:bupranolol, isosorbide dinitrate drug combination; D002046:Bupranolol; D007548:Isosorbide Dinitrate
Wirkung von Oxycardin im Akutversuch auf den Augeninnendruck von Patienten mit chronischem Glaucoma simplex