The role of 6-phosphogluconate dehydrogenase in Rhizobium.
A nicotinamide adenine dinucleotide (NAD) linked 6-phosphogluconate (6-PG)dehydrogenase has been detected in Rhizobium. The enzyme activity is similar in both slow- and fast-growing rhizobia. The nicotinamide adenine dinucleotide phosphate (NADP) dependent 6-PG dehydrogenase was detected only in the fast growers and was more than twice as active as the NAD-linked enzyme. Partial characterization of the products of 6-PG oxidation in Rhizobium suggests that the NADP-linked enzyme is the decarboxylating enzyme of the pentose phosphate (PP) pathway (EC 1.1.1.44) whereas a phosphorylated six-carbon compound, containing ketonic group(s), is the product of the oxidation catalyzed by the NAD-linked enzyme.
D002474:Cell-Free System; D005942:Gluconates / Q000378:metabolism; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism*; D012231:Rhizobium / Q000201:enzymology* / Q000254:growth & development; D013045:Species Specificity
D005942:Gluconates; D009243:NAD; D009249:NADP; D010734:Phosphogluconate Dehydrogenase