[Diphenylhydantoin. Metabolism, pharmacokinetics, interactions and side effects].
The metabolism, mechanism of action, interactions with other drugs and side effects of diphenylhydantoin (DPH), which is probably the most commonly used antiepileptic drug are reviewed in the light of the recent literature. Some findings of practical importance are emphasized, and the resultant implications with regard to the management of epileptic patients are discussed.
D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001569:Benzodiazepines; D001853:Bone Marrow / Q000187:drug effects; D001842:Bone and Bones / Q000187:drug effects; D002220:Carbamazepine / Q000494:pharmacology; D002526:Cerebellar Diseases / Q000139:chemically induced; D002540:Cerebral Cortex / Q000187:drug effects; D004071:Digitalis Glycosides / Q000494:pharmacology; D004336:Drug Antagonism; D004357:Drug Synergism; D004827:Epilepsy / Q000188:drug therapy; D006207:Half-Life; D006628:Hirsutism / Q000139:chemically induced; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007408:Intestinal Absorption; D007676:Kidney Failure, Chronic / Q000150:complications; D008107:Liver Diseases / Q000150:complications; D008286:Malabsorption Syndromes / Q000209:etiology; D009154:Mutation / Q000187:drug effects; D010672:Phenytoin; D012995:Solubility
D014151:Anti-Anxiety Agents; D004071:Digitalis Glycosides; D001569:Benzodiazepines; D002220:Carbamazepine; D010672:Phenytoin
Diphenylhydantoin. Metabolismus, Wirkungsweise, Interaktionen und Nebenwirkungen