Evaluation of d-norgestrel 1.0 mg as a post-coital contraceptive.
Two hundred and ninety-eight women were followed for 2578 months (2739 'bleeding intervals') of treatment with d-Norgestrel 1.0 mg given as a post-coital oral contraceptive. Fourteen pregnancies were recorded (general failure rate, 6.5 per 100 woman/years); at least 6 of these patients did not miss any tablet (corrected failure rate, 2.8). The acceptability rates (life table method) were 0.58 and 0.40 after 6 and 12 months of follow-up. The most important medical reason for drop-out was cycle irregularities. The cycle pattern is deeply disturbed by this method of oral contraception.
D000293:Adolescent; D000328:Adult; D003281:Contraceptives, Postcoital; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008598:Menstruation; D008599:Menstruation Disturbances / Q000139:chemically induced; D008875:Middle Aged; D009644:Norgestrel / Q000008:administration & dosage / Q000009:adverse effects
D003281:Contraceptives, Postcoital; D009644:Norgestrel