The effect of a sodium citrate preparation compared with an aluminium-magnesium hydroxide preparation on the urinary pH of normal subjects.
The effects of a sodium citrate preparation in two dosage regimens (4 g 4 times daily and 8 g 4 times daily) and of an aluminium-magnesium hydroxide suspension (15 ml 4 times daily) on the urinary pH of 19 healthy subjects were compared. The sodium citrate preparation in both dosages proved to be superior to the aluminium-magnesium hydroxide suspension in elevating the urinary pH. Urinary pH values as high as 8 were reached with the sodium citrate preparation. Blood pH, blood gases and electrolyte changes were within normal limits.
D000328:Adult; D000536:Aluminum Hydroxide / Q000494:pharmacology*; D001769:Blood; D002245:Carbon Dioxide / Q000097:blood; D002951:Citrates / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000494:pharmacology*; D008276:Magnesium Hydroxide / Q000494:pharmacology*; D010100:Oxygen / Q000097:blood; D013268:Stimulation, Chemical; D014556:Urine
D002951:Citrates; D002245:Carbon Dioxide; D000536:Aluminum Hydroxide; D008274:Magnesium; D008276:Magnesium Hydroxide; D010100:Oxygen