[Intragastric titration with extragastric pH-metry--a clinically applicable and reliable technique of quantitative analysis of gastric secretion (author's transl)].
A technique is described by which the secretory capacity of the stomach can be determined. It appears to be superior both to intragastric titration along with intragastric pH-metry and to common analysis of gastric juice obtained by aspiration. There is no essential difference when comparing results obtained intraindividually by intragastric titration with the pH being measured either inside or outside the stomach. When titrating intragastricly with the pH being measured extragastricly, a tube is used which can be check more easily, remains usable much longer, and - as a result of its smaller diameter - is tolerated much better by the patient. In contrast to common analysis of gastric juice obtained by aspiration, by intragastric titration with the pH being measured extragastricly gastric acid can be determined at its site of production (less volume loss and rediffusion of H+ -ions into tissue), the results obtained representing more accurately the true secretory capacity of the stomach. As can be seen from its results, the technique presented here is apt particularly to both testing antacids and the substances interfering with gastric secretion; it also appears to be superior to common analysis of gastric juice obtained by aspiration.
D000863:Antacids; D005745:Gastric Acidity Determination / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010418:Pentagastrin
D000863:Antacids; D010418:Pentagastrin
Intragastrale Titration bei extragastraler pH-Messung. Eine klinisch durchführbare und zuverlässige Methode zur quantitativen Sekretionsanalyse des Magens