[Experimental analysis of the cardiovascular effects of acebutolol, a drug with beta-adrenolytic activity].
In experiments at cardiovascular system level, acebutolol was found to possess beta-adrenolytic activity of cardioselective type associated with intrinsic beta-adrenergic, antiarrhythmic and anti-hypertensive activity. It was well tolerated systemically.
D000070:Acebutolol / Q000494:pharmacology*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D002415:Cats; D003326:Coronary Circulation / Q000187:drug effects; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006168:Guinea Pigs; D006339:Heart Rate / Q000187:drug effects; D007422:Intestines / Q000187:drug effects; D008297:Male; D009130:Muscle, Smooth / Q000187:drug effects; D011217:Practolol / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D014599:Uterus / Q000187:drug effects
D000319:Adrenergic beta-Antagonists; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D000070:Acebutolol; D011433:Propranolol; D011217:Practolol
Contributo sperimentale all'analisi delle azioni cardiovascolari dell'acebutololo, farmaco ad attività beta-adrenolitica.