[Consideration of the mesenchyme-reaction in patients with cronical liver-diseases (author's transl)].
The lysosomal glycosidase N-Acetyl-beta-glucosaminidase (beta-NAG) is involved in the breakdown of connective tissue. The activity of this enzyme was determined in sera and biopsies of liver tissue from patients with chronic diseases of the liver of different aetiology. Elevation of enzyme activity was found to be related to an increase of the mesenchymeraction in the injured liver tissue. No correlation was found between activity of beta-NAG and of GPT, gammaGT and CHE.
D000118:Acetylglucosaminidase / Q000378:metabolism; D000328:Adult; D000410:Alanine Transaminase / Q000378:metabolism; D002802:Cholinesterases / Q000378:metabolism; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008107:Liver Diseases / Q000201:enzymology* / Q000473:pathology; D008247:Lysosomes / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D005723:gamma-Glutamyltransferase / Q000378:metabolism
D005723:gamma-Glutamyltransferase; D000410:Alanine Transaminase; D002802:Cholinesterases; D000118:Acetylglucosaminidase
Zur Beurteilung der Mesenchymreaktion bei Patienten mit chronischen Leberkrankheiten.