[Comparative study using double-blind method of sultopride and thioproperazine].
This report includes a statistical analysis of the results of a double blind comparative study between sultopride and thioproperazine. Two rating scales were used: the standard B.P.R.S. and a simplified scale including 7 items: agitation--delusion--thought-disorganization--anxiety--aggressivity--hallucinations--autism. The comparison of the mean of the global scores obtained with the two rating scales shows a significant difference in activity in favour of sultopride. The analysis of the individual items shows regular modifications in favour of sultopride but these are not statistically significant. There are, also, no differences in the side-effects observed, particularly extra-pyramidal effects.
D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy; D001549:Benzamides / Q000009:adverse effects; D010054:Brief Psychiatric Rating Scale; D002986:Clinical Trials as Topic; D003702:Delusions / Q000188:drug therapy; D004311:Double-Blind Method; D004341:Drug Evaluation; D006212:Hallucinations / Q000188:drug therapy; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D010640:Phenothiazines / Q000627:therapeutic use*; D013469:Sulpiride / Q000031:analogs & derivatives* / Q000627:therapeutic use
D014150:Antipsychotic Agents; D001549:Benzamides; D010640:Phenothiazines; D013469:Sulpiride
Etude comparative en double insu du sultopride et de la thiopropérazine.