[Effect of arterial hypoxia and acidosis on fibrillation threshold in the cat heart in vivo].
The influence of severe arterial hypoxia and acidosis on the fibrillation threshold was checked in 22 cats. Two groups were formed: in 10 cats (group I) acidosis was produced by 2-N lactic acid infusion; in the second group of 12 animals the respirator was turned off for 60 seconds, thus producing a low arterial PO2. If hypoxia and acidosis were severe enough, the fibrillation threshold was significantly lowered in either group. The pathophysiological mechanisms of these findings are discussed.
D000138:Acidosis / Q000503:physiopathology*; D000818:Animals; D001158:Arteries; D002415:Cats; D005260:Female; D006863:Hydrogen-Ion Concentration; D000860:Hypoxia / Q000503:physiopathology*; D007773:Lactates; D008297:Male; D008433:Mathematics; D014693:Ventricular Fibrillation / Q000503:physiopathology*
D007773:Lactates
Der Einfluss einer arteriellen Hypoxie und Azidose auf die Flimmerschwelle des Katzenherzens in vivo