[Rapid production of a biotin deficiency in mice].
This work describes a rapid method for the production of a biotin-deficiency in mice. Besides classical morphological symptoms, a decrease of activities of some biotin-dependent enzymes was also observed. The biotin-enzymes are not inhibited at the same extent in a same organ and the metabolic changes do not always follow the enzymatic modifications.
D000103:Acetyl-CoA Carboxylase / Q000378:metabolism; D000818:Animals; D001710:Biotin / Q000172:deficiency*; D005227:Fatty Acids / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D051379:Mice; D011766:Pyruvate Carboxylase / Q000378:metabolism
D005227:Fatty Acids; D001710:Biotin; D011766:Pyruvate Carboxylase; D000103:Acetyl-CoA Carboxylase
Production rapide d'une carence en biotine chez la souris