Fluroxene (2,2,2-trifluoroethyl vinyl ether) mediated destruction of cytochrome P-450 in vitro.
D000818:Animals; D001580:Benzopyrenes / Q000494:pharmacology; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D004987:Ethers / Q000494:pharmacology*; D005019:Ethyl Ethers / Q000494:pharmacology; D006418:Heme / Q000378:metabolism; D066298:In Vitro Techniques; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D013997:Time Factors
D001580:Benzopyrenes; D065607:Cytochrome P-450 Enzyme Inhibitors; D004987:Ethers; D005019:Ethyl Ethers; D006418:Heme; D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D009251:NADPH-Ferrihemoprotein Reductase; D010634:Phenobarbital