A 31P-NMR study of the interaction of Mg2+ ions with nucleoside diphosphates.
The interaction of Mg2+ with nucleoside disphosphates : ADP, GDP, CDP and UDP has been studied by phosphorus magnetic resonance spectroscopy in aqueous solution. The results show that these four nucleotides behave similarly, the Mg2+ ion binds to the alpha but not to the beta phosphate moiety. The strength of the interaction of Mg2+ ions with nucleoside diphosphates is weaker than with nucleoside triphosphates. The association of Mg2+ on the phosphate chain is stronger in a neutral than in an acid medium.
D001665:Binding Sites; D002413:Cations, Divalent; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008274:Magnesium; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012265:Ribonucleotides
D002413:Cations, Divalent; D012265:Ribonucleotides; D008274:Magnesium