Drug-induced handwriting changes: an empirical review.
Since handwriting is a highly complex, coordinated motor activity, handwrits of pharmacological agents. Its potential has been most evident in research involving therapeutic administrations of anti-psychotic an  anti-Parkinsonian drugs, from which consistent and systematic handwriting changes have been observed. This relationship has been found to be particularly significant among the anti-psychotics, since the onset of these graphomotor alterations appear to mark the optmal dose of the drug. Consistent and systematic handwriting changes have not been as evident in inivestigations of drugs used in a nontherapeutic atmosphere. Psychiatric assessments of subjects in ths type of research provided data which indicated that psychological stability may be a factor influencing the susceptibility of one's handwriting to drug induced changes.
D000328:Adult; D000978:Antiparkinson Agents / Q000494:pharmacology*; D014150:Antipsychotic Agents / Q000494:pharmacology*; D000431:Ethanol / Q000494:pharmacology; D005260:Female; D006236:Handwriting; D006801:Humans; D007980:Levodopa / Q000494:pharmacology; D008238:Lysergic Acid Diethylamide / Q000494:pharmacology; D008297:Male; D008620:Meprobamate / Q000494:pharmacology; D008875:Middle Aged; D009043:Motor Activity / Q000187:drug effects; D011562:Psilocybin / Q000494:pharmacology
D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D011562:Psilocybin; D000431:Ethanol; D007980:Levodopa; D008238:Lysergic Acid Diethylamide; D008620:Meprobamate