Mapping of the locus involved in the catabolic oxidation of D-amino acids in Pseudomonas aeruginosa PAO.
Mutants of Pseudomonas aeruginosa PAO deficient in their utilization of DL-valine have been found to have lost their capacity to utilize DL-alanine and L-proline. Use of conjugal and transductional mediated gene transfers have established the chromosomal location of this gene and also its pleotropic function in the induction of the D-amino acid oxidase, involved in the oxidative utilization of DL-valine, DL-alanine and L-proline. These point mutations are clustered in a single locus designated as Val D and mapped around the 19th minute on the chromosome.
D000409:Alanine / Q000378:metabolism; D002874:Chromosome Mapping; D003227:Conjugation, Genetic; D003605:D-Amino-Acid Oxidase / Q000235:genetics*; D005796:Genes; D009154:Mutation; D011392:Proline / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000235:genetics*; D014161:Transduction, Genetic; D014633:Valine / Q000378:metabolism
D011392:Proline; D003605:D-Amino-Acid Oxidase; D014633:Valine; D000409:Alanine