2,3,7,8-Tetrachlorodibenzofuran in a commercially available 99% pure polychlorinated biphenyl isomer identified as the inducer of hepatic cytochrome P-448 and aryl hydrocarbon hydroxylase in the rat.
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000096:biosynthesis*; D001572:Benzofurans / Q000494:pharmacology*; D003580:Cytochromes / Q000096:biosynthesis*; D004147:Dioxins / Q000494:pharmacology; D004347:Drug Interactions; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D011078:Polychlorinated Biphenyls / Q000494:pharmacology*; D051381:Rats
D001572:Benzofurans; D003580:Cytochromes; D004147:Dioxins; D011078:Polychlorinated Biphenyls; D001189:Aryl Hydrocarbon Hydroxylases