Relationship of pH of blood and aqueous with vitamin C.
Blood pH, aqueous pH, and intraocular tension were noted in 20 albino rabbits before and after administration of vitamin C in oral dosage of 7.5 gm/kg/day (in 4 equal divided doses for one week). A significant difference was noted in changes of blood pH and fall in intraocular tension but aqueous pH did not show any change. In 20 glaucoma patients there was no significant change in pH of blood of glaucoma after administration of vitamin C in 3.5 gm/kg body weight per day by oral route for one week (in 4 equal divided doses).
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000818:Animals; D001082:Aqueous Humor / Q000187:drug effects*; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001769:Blood / Q000187:drug effects*; D004334:Drug Administration Schedule; D005901:Glaucoma / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D011817:Rabbits
D001205:Ascorbic Acid