[Alteration of several indices of carbohydrate metabolism in the blood and cerebrospinal fluid following surgery on patients with intracranial aneurysms].
The content of the lactic acid (LA) and pyruvic acid (PA) was determined pre- and postoperatively in the arterial blood and CSF of 31 patients with intracranial aneurysms. A considerable elevation of the concentration of LA and PA was noted along with an increasing LA/PA in the CSF of patients with symptoms of ischaemic damage of the brain. During surgery under fluothane narcosis these patients also demonstrated a distinct elevation of the LA level along with an increasing LA/PA ratio. In the CSF the growing content of glycolysis metabolites was not accompanied by LA/PA changes. The employment of artificial hypotension had no important effect upon the changes of these parameters in the CSF.
D000328:Adult; D000770:Anesthesia, Endotracheal; D001921:Brain / Q000098:blood supply; D002245:Carbon Dioxide / Q000097:blood; D002343:Carotid Artery, Internal; D002539:Cerebral Arterial Diseases / Q000601:surgery; D002941:Circle of Willis; D005260:Female; D006221:Halothane; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007023:Hypotension, Controlled; D002532:Intracranial Aneurysm / Q000097:blood / Q000134:cerebrospinal fluid / Q000601:surgery*; D007511:Ischemia / Q000150:complications; D007773:Lactates / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D011773:Pyruvates / Q000032:analysis*
D007773:Lactates; D011773:Pyruvates; D002245:Carbon Dioxide; D006221:Halothane
Izmeneniia nekotorykh pokazateleĭ uglevodnogo obmena v krovi i spinnomozgovoĭ zhidkosti pri operatsiiakh u bol'nykh s vnutricherepnymi anevrizmami.