Perfusion characteristics of preserved canine kidneys subjected to warm ischaemia.
Canine kidneys were subjected to 0, 15 or 30 min of warm ischaemia followed by 24 hours preservation by perfusion. Changes in perfusate concentration of acid radicles, lactate, free fatty acid and lactice dehydrogenase were assessed at 1 hour and 24 hours. With the exception of LDH concentration at 1 hour, no single parameter was capable of detecting kidneys which were so damaged as to be non-life supporting.
D000818:Animals; D004285:Dogs; D005230:Fatty Acids, Nonesterified / Q000032:analysis; D005260:Female; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007511:Ischemia / Q000503:physiopathology*; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology*; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D007773:Lactates / Q000032:analysis; D009926:Organ Preservation; D010477:Perfusion; D013696:Temperature; D013997:Time Factors; D014021:Tissue Preservation
D005230:Fatty Acids, Nonesterified; D007773:Lactates; D007770:L-Lactate Dehydrogenase