[Side effects of antibiotics in rheumatic diseases].
Complications due to antibiotic therapy in rheumatic patients subjected to season bicillin prophylaxis in Minsk within 1965--1975 and in patients with extensive collagenoses were studied. Allergic complications mainly ih the form of allergic reactions in the patients treated with bicillin-3 or picillin-5 were observed in 7.8--16.8 per cent of the patients. Within 10 years 52 cases of anaphylactic shock due to the bicillin use were recorded. Side reactions to antibiotics were observed in 16 (17.3 per cent) out of 92 patients with extensive collagenoses. For prophylaxis of the above complications it is recommended to use rational antibiotic therapy in rheumatic patients, strict registration of allergological states in the anamnesis, testing of microbial sensitivity to the antibiotics.
D000707:Anaphylaxis / Q000139:chemically induced; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D003882:Dermatomyositis / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000453:epidemiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy; D010401:Penicillin G Benzathine / Q000009:adverse effects; D010488:Polyarteritis Nodosa / Q000188:drug therapy; D012216:Rheumatic Diseases / Q000188:drug therapy*; D012595:Scleroderma, Systemic / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D010401:Penicillin G Benzathine
O pobochnom deĭstvii antibiotikov pri revmaticheskikh zabolevaniiakh.