[Flunitrazepam, trazodone and sulpiride in the treatment of recovery reactions after ketamine anesthesia].
The authors studied the effects of flunitrazepam, trazodone and sulpiride on recovery reactions following ketamine anaesthesia, in male patients aged between 15 and 25 years, following minor orthopaedic surgery. Only flunitrazepam and trazodone proved to be effective, whilst sulpiride was quite useless in the prevention of recovery reactions. The authors nevertheless feel that trazodone is preferable to flunitrazepam since it reduces all recovery reactions and, in particular, because it reduces the agitation induced by ketamine, rendering the pseudo-hallucinations pleasant, and because it is free of the hypnotic component of flunitrazepam, often inconstant and sometimes responsible for the patient swallowing his tongue.
D000293:Adolescent; D000328:Adult; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D002319:Cardiovascular System / Q000187:drug effects; D004341:Drug Evaluation; D005445:Flunitrazepam / Q000627:therapeutic use*; D006801:Humans; D007649:Ketamine / Q000009:adverse effects*; D008297:Male; D010879:Piperazines / Q000627:therapeutic use*; D011182:Postoperative Care; D013469:Sulpiride / Q000627:therapeutic use*; D014196:Trazodone / Q000627:therapeutic use*
D014151:Anti-Anxiety Agents; D010879:Piperazines; D005445:Flunitrazepam; D007649:Ketamine; D013469:Sulpiride; D014196:Trazodone
Le flunitrazépam, la trazodone et le sulpiride dans le traitement des réactions d'emergence après anesthésie à la kétamine.