Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation.
D000818:Animals; D000873:Anthracenes / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D001711:Biotransformation / Q000187:drug effects; D003630:Daunorubicin / Q000494:pharmacology; D004317:Doxorubicin / Q000494:pharmacology; D004579:Electron Transport / Q000187:drug effects*; D004790:Enzyme Induction / Q000187:drug effects; D005609:Free Radicals; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D008931:Mitochondria, Muscle / Q000187:drug effects / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism / Q000648:ultrastructure; D009249:NADP / Q000378:metabolism; D010101:Oxygen Consumption / Q000187:drug effects; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D013268:Stimulation, Chemical
D000873:Anthracenes; D000903:Antibiotics, Antineoplastic; D005609:Free Radicals; D009249:NADP; D004317:Doxorubicin; D010634:Phenobarbital; D003630:Daunorubicin