Immediate hypersensitivity in the guinea pig conjunctiva. II. Effect of treatment with antihistamines, steroids and disodium cromoglycate.
The effects of antihistamines, steroids and disodium cromoglycate on an immediate hypersensitivity reaction in the guinea pig eye are described in terms of clinical observations, histological examinations of sections of eyes and cytological studies of material from the conjunctival surface. The use of brushes to sample the cells on the conjunctival surface is described. The effect of repeated daily challenges on the reaction is also reported.
D000818:Animals; D000865:Antazoline / Q000627:therapeutic use; D003228:Conjunctiva / Q000276:immunology* / Q000473:pathology; D003348:Cortisone / Q000627:therapeutic use*; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006969:Hypersensitivity, Immediate / Q000188:drug therapy* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use*; D011398:Promethazine / Q000627:therapeutic use; D014311:Triprolidine / Q000627:therapeutic use
D006634:Histamine H1 Antagonists; D014311:Triprolidine; D000865:Antazoline; D011398:Promethazine; D004205:Cromolyn Sodium; D003348:Cortisone; D011241:Prednisone