[Hydrogen ion activity in the cell].
Literature data and results of our experiments evidence for a heterogenous hydrogen distribution in cells. Intracellular pH should be regarded as a mean activity of hydrogen ions which is the sum of activities in different phases of a cell. Intracellular pH value does not depend on the transmembrane action potential difference, and is resistant to respiratory and metabolic disorders of acid-base equilibrium in the body. It also slightly changes with changing the electrolyte composition and pH of the medium and is not influenced by metabolic inhibitors. A low hydrogen activity in the cell has a certain functional significance. The pH stability is ensured by a number of regulatory mechanism: the buffer properties of the protoplasm itself, and the active hydrogen transport into the medium. Hydrogen released from cells is supposed to be connected with functioning of a specific respiratory chain of superficial protoplasmic membranes.
D000085:Acetates / Q000494:pharmacology; D000818:Animals; D001693:Biological Transport, Active; D002462:Cell Membrane / Q000378:metabolism; D002477:Cells / Q000378:metabolism*; D003486:Cyanides / Q000494:pharmacology; D004140:Dinitrophenols / Q000494:pharmacology; D004285:Dogs; D004579:Electron Transport; D005724:Ganglia / Q000378:metabolism; D006801:Humans; D006859:Hydrogen / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D008564:Membrane Potentials / Q000187:drug effects; D009132:Muscles / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012908:Snails / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D000085:Acetates; D003486:Cyanides; D004140:Dinitrophenols; D006859:Hydrogen; D012964:Sodium; D011188:Potassium
Aktivnost' vodorodnykh ionov v kletke