Human mitochondrial NADP-dependent isocitrate dehydrogenase in man-mouse somatic cell hybrids.
Human mitochondrial NADP-dependent isocitrate dehydrogenase (IDH-2) is expressed in man-mouse somatic cell hybrids as a dimeric molecule. The gene specifing this enzyme was observed to be syntenic with the mannose phosphate isomerase locus in the 56 primary man-mouse clones in this series. The human IDH-2 locus, therefore, may be assigned to chromosome 15.
D000818:Animals; D002901:Chromosomes, Human, 13-15; D004789:Enzyme Activation; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology*; D007521:Isocitrate Dehydrogenase / Q000378:metabolism*; D051379:Mice; D008928:Mitochondria / Q000201:enzymology; D009249:NADP
D009249:NADP; D007521:Isocitrate Dehydrogenase