[Combination of R3365 (piritramide) and dehydrobenzperidol in animals. Respiratory effects and analgesia].
1 -- Respiratory depression has been studied in the no anaesthetized rabbit by analysis of the blood gases after an injection of Piritramide (R 3365) and dehydrobenzperidol. 2 -- The respiratory depression induced by Piritramide alone is less important after an injection of dehydrobenzperidol; the most interessant cases are: -- mixture dehydrobenzperidol 400 mug/kg. Pirittramide 1000 mug/kg; --dehydrobenzperidol (400 mug/kg) injected 15 minutes before Piritramide (1000 mug/kg). 3 -- The addition of Dehydrobenzperidol does not take the analgesic activity of Piritramide decrease by it increases it.
D000700:Analgesics; D000818:Animals; D003864:Depression, Chemical; D004329:Droperidol; D004338:Drug Combinations; D004357:Drug Synergism; D007540:Isonipecotic Acids / Q000494:pharmacology*; D010880:Piperidines / Q000494:pharmacology*; D011817:Rabbits; D012119:Respiration / Q000187:drug effects*
D000700:Analgesics; D004338:Drug Combinations; D007540:Isonipecotic Acids; D010880:Piperidines; D004329:Droperidol
Association du R 3365 (piritramide) et du déhydrobenzpéridol chez l'animal. Actions sur la respiration et l'analgésie