[Pharmacology of methvin--a new ganglionic blocking preparation of short-term effect].
Methvin (vincanin chlormethylate) is an active ganglion blocking agent of a short-term action. As regards its gangliolytic action it is approximately 6 times superior to afronad. In test animals the drug produces a well-marked and short-term (easily controllable) hypotensive effect, without causing any histamine-like and direct vasodilation action. When used in relatively high doses methvin blocks the neuro-muscular conduction, potentiates the action of major muscle relaxants. A study of methvin in clinical conditions confirmed its high gangliolytic activity previously revealed in experiments.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004353:Drug Evaluation, Preclinical; D005730:Ganglionic Blockers / Q000008:administration & dosage / Q000494:pharmacology*; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology; D013997:Time Factors
D005730:Ganglionic Blockers; D009466:Neuromuscular Blocking Agents
K farmakologii metvina--novogo ganglioblokiruiushchego preparata kratokovremennogo deĭstviia