Methods for determination of prekallikrein in plasma, glandular kallikrein and urokinase.
New chromogenic tripeptide substrates have been used for the determination of kallikreins and urokinase. The conditions have been optimized. It is possible to determine prekallikrein in plasma after activation with Cephotest. No significant loss in activity caused by plasma kallikrein inhibitors is observed at the dilutions used.
D010450:Endopeptidases / Q000032:analysis*; D005175:Factor XII Deficiency / Q000201:enzymology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007610:Kallikreins / Q000032:analysis* / Q000037:antagonists & inhibitors; D007616:Kaolin / Q000494:pharmacology; D008722:Methods; D011288:Prekallikrein / Q000032:analysis*; D014568:Urokinase-Type Plasminogen Activator / Q000032:analysis*
D007616:Kaolin; D011288:Prekallikrein; D010450:Endopeptidases; D007610:Kallikreins; D014568:Urokinase-Type Plasminogen Activator