Scleroderma-like changes in chronic graft vs host disease.
A case of chronic graft vs host disease had scleroderma-like skin changes. Clinical progression was from poikiloderma to scleroderma, and histopathological changes and results of direct immunofluorescence were noted. It is probable that both cell-mediated (T-cell) and humoral (B-cell) mechanisms contribute to the pathogenesis of the graft vs host reaction.
D000293:Adolescent; D016026:Bone Marrow Transplantation; D002908:Chronic Disease; D003176:Complement C3; D005260:Female; D006087:Graft vs Host Reaction; D006801:Humans; D007070:Immunoglobulin A; D007075:Immunoglobulin M; D008297:Male; D012595:Scleroderma, Systemic / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D014184:Transplantation, Homologous
D003176:Complement C3; D007070:Immunoglobulin A; D007075:Immunoglobulin M