[Synthesis of N-substituted isoindolines].
Some derivatives of isoindoline were prepared in order to test their cardiovascular activity. Pharmacological tests showed that some of the compounds had moderate alpha-blocking and coronarodilatory activity whereas others had some local anesthetic activity.
D000319:Adrenergic beta-Antagonists / Q000138:chemical synthesis*; D000779:Anesthetics, Local / Q000138:chemical synthesis*; D001562:Benzimidazoles; D007211:Indoles / Q000138:chemical synthesis*; D014665:Vasodilator Agents / Q000138:chemical synthesis*
D000319:Adrenergic beta-Antagonists; D000779:Anesthetics, Local; D001562:Benzimidazoles; D007211:Indoles; D014665:Vasodilator Agents
Sintesi di isoindoline N-sostituite