[Value of brain metabolic studies in post-traumatic coma].
In 34 comatose patients in the acute phase, the mean hemispheric CBF is lowered as well as the CMRO2, with a quite good relation between these values and the coma level and prognostic so. The cerebral response to a PaCO2 range indicates a quite good relation with the coma level (the lowest value in the most severe comas). The cerebral autoregulation study, using Aramine induced hypertension, can separate the cases with a present autoregulation and the cases with a loss of autoregulation (the most severe and the poorest prognosis). In dynamic conditions (variation of the PaCO2 or Aramine induced hypertension), the change in CMRO2 is interesting : rather good prognosis among the patients with a normal metabolic autoregulation - poor prognosis among those whose metabolic autoregulation is lost.
D001921:Brain / Q000378:metabolism*; D001927:Brain Diseases / Q000150:complications; D001930:Brain Injuries / Q000150:complications; D002245:Carbon Dioxide / Q000097:blood; D002560:Cerebrovascular Circulation; D003128:Coma / Q000209:etiology / Q000378:metabolism*; D005260:Female; D006706:Homeostasis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006935:Hypercapnia / Q000378:metabolism; D006973:Hypertension / Q000139:chemically induced / Q000378:metabolism; D008297:Male; D008680:Metaraminol; D010101:Oxygen Consumption
D002245:Carbon Dioxide; D008680:Metaraminol
Intérêt de l'exploration métabolique cérébrale dans les états de coma post-traumatique.