Acidic in vivo metabolites of cannabinol isolated from rat faeces.
Six acidic metabolites were isolated from rat faeces and identified by gas chromatographymass spectrometry and proton magnetic resonance. Cannabinol-7-oic acid was the most abundant acidic metabolite isolated. Others present in decreasing order of prominence were 1"-hydroxy-, 4"-hydroxy-, 3"-hydroxycannabinol-7-oic acid, cannabinol-3"-one-7-oic acid and 2"-hydroxycannabinol-7-oic acid.
D000818:Animals; D001711:Biotransformation; D002186:Cannabinoids / Q000378:metabolism*; D002187:Cannabinol / Q000378:metabolism*; D002849:Chromatography, Gas; D005243:Feces / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051381:Rats
D002186:Cannabinoids; D002187:Cannabinol