[Correlations between age, risk factors for arteriosclerosis and endocrine functions (author's transl)].
In 377 males and 528 female factory workers basal serum levels of glucose, neutralfat, cholesterol, Na, K, Ca and LH, FSH, TSH, Prolactin, GH, Insulin, total corticoids and testosteron were determined. Mean values and standard deviations as well as correlations between mean basal hormone levels and other serum parameters, blood pressure and relative body weight (Broca Index) and partial correlations excluding age and relative body weight were calculated. Basal serum levels of LH, FSH, GH and prolactin show age and sex dependent secretion patterns. In men serum insulin-, GH- and total corticoid levels correlate positive significant with glucose and cholesterol levels, relative body weight and blood pressure, which possibly shows, that these hormones may play a role in the development of degenerative heart and blood vessel diseases. Testosteron levels and parameters of fat metabolism, relative body weight and diastolic blood pressure correlate negative significant. Obviously testosteron has a protective effect against arterioslcerotic lesions. In women insulin and GH do not have the same importance as in men. Prolactin serum and cholesterol level correlate negative significant. In postmenopausal women LH and FSH serum levels correlate positive significant with glucose and cholesterol levels, blood pressure and relative body weight, the so called risk factors for arteriosclerosis.
D000328:Adult; D000368:Aged; D000375:Aging; D001161:Arteriosclerosis / Q000209:etiology*; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000503:physiopathology; D002784:Cholesterol / Q000097:blood; D004573:Electrolytes / Q000097:blood; D004702:Endocrine Glands / Q000503:physiopathology*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood; D012306:Risk; D012737:Sex Factors; D013972:Thyrotropin / Q000097:blood
D001786:Blood Glucose; D004573:Electrolytes; D007328:Insulin; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013006:Growth Hormone; D002784:Cholesterol
Uber Beziehungen zwischen Alter, Risikofaktoren für Herz- und Kreislauferkrankungen und Endokrinium. Eine Feldstudie mit 905 Mitarbeitern einer Fabrik.