[Sedimentation rate of erythrocytes as an indicator for phase transitions in the membrane].
Temperature dependent sedimentation measurements with human erythrocytes showed that the sedimentation velocity at 21 degrees C in Krebs-Ringer-solution, pH 7.4, has a peak shaped minimum [1]. In further investigations it could be shown that a phase transition of membrane lipids is the main reason of this peak. Membrane proteins influence the sedimentation behavior of the erythrocytes only by changing the interaction with membrane lipids.
D001799:Blood Sedimentation; D004910:Erythrocyte Membrane / Q000502:physiology*; D004912:Erythrocytes / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008563:Membrane Lipids / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology*; D009994:Osmolar Concentration; D013696:Temperature
D008563:Membrane Lipids; D008565:Membrane Proteins
Die Sedimentationsgeschwindigkeit von Erythrozyten als Indikator für Phasenübergänge in der Membran.