Modification of neonatal screening test for erythrocyte glucose-6-phosphate dehydrogenase deficiency.
An improved technique is proposed for detecting G6PD deficiency on dried blood. A simple and rapid ascending chromatography of NADPH makes it possible to differentiate the false positives, too frequently found with Beutler's spot test (1968).
D002854:Chromatography, Paper; D004912:Erythrocytes / Q000201:enzymology*; D005189:False Positive Reactions; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009249:NADP / Q000378:metabolism; D013050:Spectrometry, Fluorescence
D009249:NADP