[Gastric secretion in rats during long-term histamine administration].
The acid--forming, acid--neutralizing functions of the stomach, morphological state of its walls and level of histamine in the blood were studied in control rats and in rats subjected to continuous histamine administration. In the latter, intensive elevation of intragastric acidity in empty stomach, an increase in the histamine contents in the blood, and distrophic processes in the wall of stomach occurred. The functional--morphological data obtained suggest remarkable adaptational abilities of the stomach.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006632:Histamine / Q000494:pharmacology*; D006651:Histocytochemistry; D006863:Hydrogen-Ion Concentration; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
D006025:Glycosaminoglycans; D001285:Atropine; D006632:Histamine; D013385:Succinate Dehydrogenase
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