Acid-base and gas tension of cerebrospinal fluid in Nigerians and tetanus patients.
The acid-base balance and gas tension of the cerebrospinal fluid of eight tetanus patients and twelve control subjects were studied. Tetanus patients had metabolic acidosis which was severely reflected in the cerebrospinal fluid. While the cerebrospinal fluid pH is lower than that of the arterial blood there was no difference between the acid-base and gas tension of the cerebrospinal fluid of Nigerians and the causasians. The severe metabolic acidosis of the cerebrospinal fluid of tetanus patients might be one of the causes of sudden deaths seen in these patients.
D000137:Acid-Base Imbalance / Q000134:cerebrospinal fluid*; D000293:Adolescent; D000328:Adult; D001639:Bicarbonates / Q000134:cerebrospinal fluid*; D002245:Carbon Dioxide / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D009549:Nigeria; D010100:Oxygen / Q000134:cerebrospinal fluid*; D013742:Tetanus / Q000134:cerebrospinal fluid*
D001639:Bicarbonates; D002245:Carbon Dioxide; D010100:Oxygen