pH of sweat of patients with cystic fibrosis.
pH of the sweat from patients with cystic fibrosis and in controls was measured as a function of the sweat-rate using a fluorescence-pH-indicator (umbelliferone). In both populations sweat is acid at low sweat-rates and alkaline at high ones. The results do not favour an abnormality of the ductal H+-secretion as the pathomechanism of cystic fibrosis.
D001639:Bicarbonates / Q000378:metabolism; D003550:Cystic Fibrosis / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D013542:Sweat / Q000032:analysis*; D013546:Sweating
D001639:Bicarbonates