[Flunitrazepam and memory (author's transl)].
This work is based on the observation of memory troubles before sleep in patients with sleep problems treated with flunitrazepam. Eight subjects are tested in two sessions, flunitrazepam and placebo, in double blind, with memory tests given the evening after medication and controlled the next morning. One additional test is controlling vigilance. The results show that memory is significantly disturbed by flunitrazepam, both for direct and delayed memory, the next day. On the contrary, recognition is not altered, neither vigilance.
D000328:Adult; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005445:Flunitrazepam / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008568:Memory; D008569:Memory Disorders / Q000139:chemically induced*; D008875:Middle Aged; D011581:Psychological Tests; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*
D014151:Anti-Anxiety Agents; D005445:Flunitrazepam
Flunitrazepam et mémoire.