Influence of the trypsin activity by the side chain of arginine homologues.
The N-alpha-tosyl-p-nitroanilides of homoarginine and of the two shorter arginine homologues were synthesized. These compounds behave as specific, chromogenic substrates for trypsin.
D001120:Arginine / Q000031:analogs & derivatives* / Q000378:metabolism; D006709:Homoarginine / Q000031:analogs & derivatives* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D013329:Structure-Activity Relationship; D014105:Tosyl Compounds / Q000378:metabolism; D014357:Trypsin / Q000378:metabolism*
D014105:Tosyl Compounds; D006709:Homoarginine; D001120:Arginine; D014357:Trypsin