Antibacterial product of peritoneal exudate cell cultures from guinea pigs infected with mycobacteria, listeriae, and rickettsiae.
In an in vitro model of cellular immunity, the antibacterial product of immunologically mediated mononuclear cell activation was studied from guinea pigs infected with listeriae and rickettsiae and compared with the product previously described from animals infected with mycobacteria. We found that this product, active against gram-positive bacilli, appeared to be  identical in the three different infections with regard to its heat stability, its chromatographic adsorption and elution pattern, its susceptibility to inactivation by proteolytic enzymes, and its antibacterial spectrum
D000818:Animals; D000942:Antigens, Bacterial; D001202:Ascitic Fluid / Q000166:cytology*; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D008088:Listeriosis / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008222:Lymphokines; D008264:Macrophages / Q000276:immunology; D009164:Mycobacterium Infections / Q000276:immunology*; D012282:Rickettsia Infections / Q000276:immunology*; D013696:Temperature
D000942:Antigens, Bacterial; D008222:Lymphokines