[Molecular evolution of glycogen phosphorylase and aminotransferases of vertebrate muscle tissue].
Comparative biochemical studies on phosphorylase b, aspartate aminotransferase and alanine aminotransferase in muscles of various vertebrates (the lamprey Lampetra fluviatilis, dogfish Squalus acanthias, rays Dasyatis pastinaca and Raja clavata, teleosts Scorpaena porcus, Spicara smaris, Esox lucius, Tinca tinca, Abramis brama, Lucioperca lucioperca, Cyprinus carpio, Salmo ischchan, frog Rana temporaria, tortoise Testudo horsfieldi) revealed some peculiarties of their molecular evolution. It was shown that isoenzyme PH-II, which comprises in most on the investigated lower vertebrates the main bulk of phosphorylase b, disappears in evolution of the type. Isoenzyme PH-I which is found in fisches in small amounts, increases in evolution becoming the sole form of phosphorylase b in skeletal muscles of endothermic animals. Mitochondrial and cytoplasmic isoenzymes of aspartate aminotransferase were found in all the vertebrates studied. Cytoplasmic isoenzyme from ectothermic and endothermic animals does not differ significantly, whereas the mitochondrial one undergoes considerable changes in the evolution of vertebrates.
D000410:Alanine Transaminase / Q000032:analysis; D000818:Animals; D001001:Anura; D001219:Aspartate Aminotransferases / Q000032:analysis; D005075:Biological Evolution; D002347:Carps / Q000378:metabolism; D002384:Catalysis; D002645:Chickens / Q000378:metabolism; D002848:Chromatography, DEAE-Cellulose; D004587:Electrophoresis, Agar Gel; D005399:Fishes / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes / Q000032:analysis; D007798:Lampreys / Q000378:metabolism; D006005:Phosphorylases / Q000032:analysis; D011489:Protein Denaturation; D011817:Rabbits; D011896:Rana temporaria / Q000378:metabolism; D013696:Temperature; D014426:Turtles / Q000378:metabolism
D007527:Isoenzymes; D006005:Phosphorylases; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Nekotorye osobennosti molekuliarnoĭ évoliutsii glikogen-fosforilazy i aminotransferaz myshechnoĭ tkani pozvonochnykh