Catatonialike symptomatology and withdrawal dyskinesias.
The authors describes a patient who presented catatonialike symptoms and dyskinesias associated with glutethimide discontinuance and antihistamine use. He hypothesizes that altered dopamine metabolism may produce some of the unusual neuropsychiatric characteristics of glutethimide withdrawal. Drug-withdrawal catatonia may be an additional entity in the differential diagnosis of catatonialike states of organic etiology.
D000328:Adult; D001921:Brain / Q000378:metabolism; D002389:Catatonia / Q000139:chemically induced*; D004298:Dopamine / Q000378:metabolism; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D005149:Facial Expression; D005260:Female; D005984:Glutethimide / Q000009:adverse effects*; D006634:Histamine H1 Antagonists / Q000009:adverse effects*; D006801:Humans; D013375:Substance Withdrawal Syndrome
D006634:Histamine H1 Antagonists; D005984:Glutethimide; D004298:Dopamine