Metabolic changes induced by acute phosphate loading in acutely thyroparathyroidectomized rats.
Phosphate loading in acutely thyroparathyroidectomized rats is followed by a decline of phosphate reabsorption. In addition, a mixed respiratory and metabolic alkalosis and hypocalcemia develop. Normalization of plasma calcium concentration, unlike the reversal of the alkalosis, prevents the fall in phosphate reabsorption.
D000818:Animals; D001769:Blood; D004573:Electrolytes / Q000097:blood; D005919:Glomerular Filtration Rate; D006863:Hydrogen-Ion Concentration; D007668:Kidney / Q000502:physiology*; D008297:Male; D010280:Parathyroid Glands / Q000502:physiology*; D010710:Phosphates / Q000378:metabolism*; D051381:Rats; D013965:Thyroidectomy; D014556:Urine
D004573:Electrolytes; D010710:Phosphates