[The effect of intravenous dopamine on the hemodynamics of the heart].
The pharmacological study of dopamine was conducted on 14 patients: eleven normal patients and three with incipient myocardiopathies. The dosages used were 3, 6 and 12 mug/kg/min. The "pump" function, the peripheral resistances, the contractility and the ventricular compliance were studied. Dopamine is a positive inotropic agent without chronotropic action at doses of 6 and 12 mug/kg/min. It acts by increasing the contractility and the venous return and by decreasing the peripheral resistances; this effect disappears with strong dosages.
D001011:Aorta; D001794:Blood Pressure / Q000187:drug effects; D006328:Cardiac Catheterization; D002302:Cardiac Output / Q000187:drug effects; D009202:Cardiomyopathies / Q000175:diagnosis; D004298:Dopamine / Q000494:pharmacology*; D005263:Femoral Artery; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects*; D011651:Pulmonary Artery
D004298:Dopamine
Effet de la dopamine i.v. sur l'hémodynamique cardiaque