Review of drug treatment for Down's syndrome persons.
A review of drug treatment for Down's syndrome individuals was presented. Drugs used to modify behavior, as well as drugs used with the goal of affecting cognitive processes, were discussed. Some observations were offered as to the effectiveness of past and current drugs on Down's syndrome and some methodological problems relating to drug studies presented. There have not been any drugs that have demonstrated remarkable improvement in the status of Down's syndrome individuals that have been widely accepted as effective.
D006916:5-Hydroxytryptophan / Q000627:therapeutic use; D000662:Amphetamines / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001519:Behavior / Q000187:drug effects*; D017690:Cell Transplantation; D003071:Cognition / Q000187:drug effects*; D004314:Down Syndrome / Q000188:drug therapy*; D004341:Drug Evaluation; D057487:Enzyme Therapy; D005971:Glutamates / Q000627:therapeutic use; D006801:Humans; D008903:Minerals / Q000627:therapeutic use; D010640:Phenothiazines; D010907:Pituitary Hormones / Q000627:therapeutic use; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012107:Research Design; D012701:Serotonin / Q000627:therapeutic use; D013963:Thyroid Hormones / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use
D000662:Amphetamines; D014150:Antipsychotic Agents; D005971:Glutamates; D008903:Minerals; D010640:Phenothiazines; D010907:Pituitary Hormones; D011619:Psychotropic Drugs; D013963:Thyroid Hormones; D014815:Vitamins; D012701:Serotonin; D006916:5-Hydroxytryptophan