Electrode sensitive to sulfa drugs.
An electrode sensitive to sulfa drugs was constructed by using the iron(II)-bathophenanthroline chelate embedded in a liquid membrane. Rapid and Nernstian responses were exhibited against solutions of sulfamerazine and sulfisomidine ranging between 10(-3) and 10(-1) M in concentration. High selectivity was observed in the presence of urea, glycine, aminopyrine, or p-amino-benzoic acid. These chemicals are known to interfere in the usual colorimetric analysis of sulfa drugs.
D055598:Chemical Phenomena; D002621:Chemistry; D004566:Electrodes; D006863:Hydrogen-Ion Concentration; D008722:Methods; D013416:Sulfamerazine / Q000032:analysis*; D013443:Sulfisomidine / Q000032:analysis*
D013416:Sulfamerazine; D013443:Sulfisomidine