Treatment of ovarian hyperstimulation syndrome by antihistamine.
Ovarian hyperstimulation was produced by human menopausal gonadotropin and chorionic gonadotropin in rabbits. A more rapid regression of the hyperstimualted ovaries was observed in an antihistamine-treated group than in a control group. The difference in regression was found to be statistically significant. The possibility of treating the ovarian hyperstimulation syndrome by antihistamine is cited.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000009:adverse effects*; D004195:Disease Models, Animal; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D007049:Iatrogenic Disease; D008596:Menotropins / Q000009:adverse effects*; D010049:Ovarian Diseases / Q000139:chemically induced / Q000188:drug therapy*; D011817:Rabbits; D013577:Syndrome
D006063:Chorionic Gonadotropin; D006634:Histamine H1 Antagonists; D008596:Menotropins