N-Halo derivatives V: Comparative antimicrobial activity of soft N-chloramine systems.
Comparative antimicrobial activity studies for certain new classes of soft N-chloramines derived from alpha-aminiisobutyric acid and 2-amino-2-methyl-1-propanol were examined using the minimum inhibitory concentration (MIC) and/or the contact germicidal efficiency (CGE) procedures. Several factors significantly aliphatic chain length in a homologous series, (b) the degree of chlorination of thenitrogen atom, (c) the solution pH, (d) the presence of a denaturant, and (e) the nature of a positive charge.
D000890:Anti-Infective Agents; D001769:Blood; D002700:Chloramines / Q000494:pharmacology*; D004347:Drug Interactions; D004563:Electrochemistry; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
D000890:Anti-Infective Agents; D002700:Chloramines