[Current aspects of gas gangrene, apropos of 47 cases collected over a 3-year period (1974-1976)].
On the basis of 47 cases of gas gangrene collected over the three year period between 1974 and 1976, the authors review the circumstances surrounding its development, the clinical features and the prognosis of the disorder which remains grave despite a well-defined therapeutic protocol combining surgery, antibiotics and hyperbaric oxygen. There would appear to be a real resurgence of the disease at the present time. Post-traumatic and surgical aetiologies predominate, giving rise to two types of gangrene: clostridial gas gangrene secondary to contamined wounds, with a quasi-constant vascular element, affecting predominantly the limbs, and nonclostridrial gangrene, the increasing prevalence of which involves essentially spetic abdomino-pelvic surgery. In the light of this study, prognosis would appear to be related to the underlying terrain in which the gangrene occurs, to certain features of the clinical picture and, above all, to the possibilities of early application of the complete therapeutic protocol. Strict prophylactic measures would alone seem capable of preventign the worrying increase in the number of cases of gas gangrene.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001441:Bacteroides fragilis / Q000302:isolation & purification; D003016:Clostridium perfringens / Q000302:isolation & purification; D005051:Eubacterium / Q000302:isolation & purification; D005260:Female; D005738:Gas Gangrene / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D010400:Penicillin G / Q000627:therapeutic use; D010462:Peptostreptococcus / Q000302:isolation & purification; D011183:Postoperative Complications; D011379:Prognosis; D014678:Veillonella / Q000302:isolation & purification; D014947:Wounds and Injuries / Q000150:complications*
D010400:Penicillin G
Actualité de la gangrène gazeuse à propos de 47 observations recueilleies en trois ans (1974-1976).