[Drug-induced lung diseases].
Adverse drug reactions involving different organs, including the lung, are numerous; much more numerous, however, are the offending drugs. According to the results of the Boston Collaborative Drug Surveillance Program, adverse reactions occur in about 6% of all drug exposures and 28% of all patients. Drug-induced lung diseases may present as bronchial reactions (e.g. bronchial asthma), diseases of the parenchyma (e.g. pulmonary infiltrates with eosinophilia, diffuse fibrosing alveolitis), of the pulmonary vasculature (vasculitis) and of the pleura (e.g. pleurisy or pleural fibrosis). Pathogenetically the two most pertinent types of reaction are hypersensitivity or toxic reactions, and less often biologic reactions such as opportunistic infections after cytotoxic and immunosuppressive therapy. Many drug-induced respiratory diseases are reversible upon withdrawal of the offending agent; others may be irreversibly or even progress.
D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001249:Asthma / Q000139:chemically induced; D001991:Bronchitis / Q000139:chemically induced; D004342:Drug Hypersensitivity; D004347:Drug Interactions; D005260:Female; D006584:Hexamethonium Compounds / Q000633:toxicity; D006801:Humans; D007455:Iodine / Q000009:adverse effects; D008168:Lung / Q000502:physiology; D008171:Lung Diseases / Q000139:chemically induced*; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced; D008875:Middle Aged; D009582:Nitrofurantoin / Q000009:adverse effects; D011014:Pneumonia / Q000139:chemically induced; D010488:Polyarteritis Nodosa / Q000139:chemically induced; D011654:Pulmonary Edema / Q000139:chemically induced; D011655:Pulmonary Embolism / Q000139:chemically induced; D011657:Pulmonary Eosinophilia / Q000139:chemically induced; D013256:Steroids / Q000009:adverse effects; D014357:Trypsin / Q000009:adverse effects
D000900:Anti-Bacterial Agents; D006584:Hexamethonium Compounds; D013256:Steroids; D009582:Nitrofurantoin; D007455:Iodine; D014357:Trypsin
Medikamentöse Lungenerkrankungen