Liver microsomal uptake of (14C)vinyl chloride and transformation to protein alkylating metabolites in vitro.
D000478:Alkylation; D000818:Animals; D001711:Biotransformation; D004851:Epoxide Hydrolases / Q000037:antagonists & inhibitors; D005978:Glutathione / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D008566:Membranes / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism*; D009249:NADP / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D013997:Time Factors; D014752:Vinyl Chloride / Q000378:metabolism*; D014753:Vinyl Compounds / Q000378:metabolism*
D011506:Proteins; D014753:Vinyl Compounds; D009249:NADP; D004851:Epoxide Hydrolases; D005978:Glutathione; D014752:Vinyl Chloride; D010634:Phenobarbital