[Effect of thymus cells on the radiosensitivity and differentiation trends of hematopoietic stem cells].
A stimulating influence of thymus cells on the capability of irradiated (from 100 to 500 r) bone marrow of mice of producing colonies in spleen of syngenous recipient has been proven. The intensification of colony formation involves an increased radioresistance of stem cells. It is supposed that radioresistant thymus cells have a stimulating effect. Thymus cells exert their influence not only to the rate of survival of stem cells proliferating in the bone marrow of femur, but also increase their erythropoetic potention.
D000818:Animals; D002999:Clone Cells; D005260:Female; D006410:Hematopoiesis / Q000528:radiation effects; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000528:radiation effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011828:Radiation Chimera; D013601:T-Lymphocytes / Q000637:transplantation*; D014184:Transplantation, Homologous
Vliianie kletok timusa na radiochuvstvitel'nost' i napravlenie differentsirovki stvolovykh krovetvornykh kletok