Intrapartum fetal asphyxia: clinical characteristics, diagnosis, and significance in relation to pattern of development.
The clinical and fetal heart rates and acid-base characteristics and their sequelae have been reviewed in 587 patients. The relevant clinical factors in the asphyxia group were the preterm fetus, the intrauterine growth retarded fetus, maternal toxemia, and midforceps delivery. The duration of the developing metabolic acidosis in the asphyxia group ranged from terminal to the last two hours of labor. Marked patterns of total decelerations and moderate and marked patterns of late decelerations are of predictive value in the diagnosis of intrapartum fetal asphyxia with a trend to an increased incidence in the longer duration categories, between four and two hours prior to delivery, and a significant increase in all categories during the last two hours of labor. The significance of intrapartum fetal asphyxia to the newborn infant is evident from the low Apgar scores, increased incidence of moderate and severe respiratory distress syndrome, and central nervous system complications in the asphixia group in relation to the normal group.
D000136:Acid-Base Equilibrium; D001034:Apgar Score; D001237:Asphyxia / Q000175:diagnosis*; D001238:Asphyxia Neonatorum / Q000150:complications / Q000175:diagnosis*; D002021:Buffers; D002245:Carbon Dioxide / Q000097:blood; D002493:Central Nervous System Diseases / Q000209:etiology; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005318:Fetal Heart / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007773:Lactates / Q000097:blood; D008171:Lung Diseases / Q000209:etiology; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D011773:Pyruvates / Q000097:blood; D014469:Umbilical Arteries; D014471:Umbilical Veins
D002021:Buffers; D007773:Lactates; D011773:Pyruvates; D002245:Carbon Dioxide; D010100:Oxygen