Premature labour.
Prematurity is by far the commonest cause of neonatal morbidity and mortality. The management of premature labour is empirical because little is understood about the mechanism of labour. Effective uterine relaxant drugs have an important, albeit minor role. Phototherapy has reduced the complications of neonatal hyperbilirubinemia, and the beneficial effect of antepartum corticosteroid therapy in minimizing the risk of respiratory distress syndrome is now convincing. Prophylactic antibiotic therapy in premature rupture of the membranes does not alter perinatal mortality, although postpartum maternal morbidity is reduced. The introduction of neonatal intensive care units has improved the survival rate of premature infants. Sound clinical judgement remains the mainstay in the management of premature labour.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000009:adverse effects; D000420:Albuterol / Q000627:therapeutic use; D000650:Amnion / Q000503:physiopathology; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001424:Bacterial Infections / Q000517:prevention & control; D001623:Betamethasone / Q000627:therapeutic use; D003981:Diazoxide / Q000627:therapeutic use; D000431:Ethanol / Q000627:therapeutic use; D005321:Extraembryonic Membranes; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007556:Isoxsuprine / Q000627:therapeutic use; D007567:Jaundice, Neonatal / Q000517:prevention & control; D007752:Obstetric Labor, Premature / Q000209:etiology / Q000628:therapy; D010634:Phenobarbital / Q000009:adverse effects / Q000627:therapeutic use; D010789:Phototherapy; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control; D012312:Ritodrine / Q000627:therapeutic use; D012422:Rupture, Spontaneous; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D000900:Anti-Bacterial Agents; D000431:Ethanol; D001623:Betamethasone; D012312:Ritodrine; D003981:Diazoxide; D000420:Albuterol; D007556:Isoxsuprine; D010634:Phenobarbital