Consumption of complement in chelated and nonchelated guinea pig serum after challenge with some viral and nonviral interferon inducers.
The consumption of complement observed during the induction of interferon by various inducers may proceed via the alternate pathway. The alternate pathway requires the presence of Mg ions in the medium while Ca ions may be absent.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D003165:Complement System Proteins / Q000378:metabolism*; D004492:Edetic Acid / Q000494:pharmacology; D004533:Egtazic Acid / Q000494:pharmacology; D004731:Endotoxins / Q000494:pharmacology; D004926:Escherichia coli; D006168:Guinea Pigs / Q000276:immunology; D007369:Interferon Inducers / Q000494:pharmacology*; D037102:Lectins / Q000494:pharmacology; D008274:Magnesium / Q000378:metabolism; D008351:Mannans / Q000494:pharmacology; D009522:Newcastle disease virus; D009975:Orthomyxoviridae; D015054:Zymosan / Q000494:pharmacology
D004731:Endotoxins; D007369:Interferon Inducers; D037102:Lectins; D008351:Mannans; D004533:Egtazic Acid; D003165:Complement System Proteins; D015054:Zymosan; D004492:Edetic Acid; D008274:Magnesium; D002118:Calcium