Serotypes of pneumococci in pneumonia, meningitis and other pneumococcal infections.
During a five-year period, 1965 to 1969 inclusive, pneumococci from 294 patients with acute pneumococcal infections were serotyped. Pneumococci of 33 serotypes were encountered, of which types 3 and 19 were most frequent. The spectrum of infections included pneumonia, meningitis, peritonitis, otitis media and mastoiditis, wound infection and conjuctivitis. At least 17 infections were fatal, all of which, with one exception, occurred either in infants or in adults over 50 years of age. In pneumonia, type 3 pneumococcus was predominant, being isolated from 21 of 101 patients. In 67 cases of pneumococcal meningitis, most of which were in children, the commonest type was 14. If a pneumococcal vaccine is produced for use in Australia, inclusion of serotypes 1, 3, 4, 6, 9, 14, 19 and 23 should be considered. These eight types caused 52% of the cases of pneumonia and 67% of the cases of meningitis in this study.
D000208:Acute Disease; D000328:Adult; D001315:Australia; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008586:Meningitis, Pneumococcal / Q000382:microbiology*; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000382:microbiology* / Q000401:mortality; D011018:Pneumonia, Pneumococcal / Q000382:microbiology*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*