A new anticoagulant medication in cardiac valve replacement.
1. In the mitral valve replacement with Starr-Edwards prosthetic ball valve, the major thromboembolism occurred in 20% of the patients with the silastic ball valve series compared with 6% in those with a metal ball valve series. 2. The anticoagulant effect of Warfarin became stable and the occurrence of thromboembolism was reduced by the addition of Bucolome.
D001463:Barbiturates / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D004347:Drug Interactions; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects* / Q000401:mortality; D006801:Humans; D008943:Mitral Valve / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control; D011485:Protein Binding; D013923:Thromboembolism / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D014859:Warfarin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D001463:Barbiturates; D004338:Drug Combinations; D014859:Warfarin