[Physiochemical properties of 7-aminoacetoxycephalosporanic acid].
Potentiometric titration of the zwitter-ion of 7-aminoacetoxycephalosporanic acid (7-ACA) was performed and the constants of its ionization were estimated. The minimum solubility of the 7-ACA zwitter-ion (20 degrees C, 0.1 M NaCl) was determined and the solubility curve of 7-ACA at wide pH ranges was calculated. Equilibrium of the cationic, zwitter-ionic and anionic forms of 7-ACA was estimated as dependent on pH.
D002511:Cephalosporins / Q000032:analysis / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006863:Hydrogen-Ion Concentration; D011199:Potentiometry; D012995:Solubility; D013696:Temperature
C015663:7-aminoacetoxycephalosporanic acid; D002511:Cephalosporins
Fiziko-khimicheskie svoĭstva 7-aminoatsetoksitsefalosporanovoĭ kisloty.