[Studies of in vitro cultivated cells from the smooth muscle organs. 3. Effectiveness of some drugs on pulsation frequency of isolated smooth muscle cells of the chicken amnion].
The effects of some drugs on the beating frequency of isolated cells of the chick amnion cultivated on cover slips were investigated. Cholinergic and adrenergic agonists and antagonists, serotonine, antispasmodics, coronary dilatants and local anesthetics influenced the beating frequency significantly. The isolated chick amnion cells equal in their pharmacological behaviour the intact chick amnion and smooth muscle cells of mammals but differ from isolated beating heart cells.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000650:Amnion / Q000166:cytology* / Q000187:drug effects; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D009130:Muscle, Smooth / Q000166:cytology* / Q000187:drug effects; D010277:Parasympathomimetics / Q000494:pharmacology; D011674:Pulse / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology
D000319:Adrenergic beta-Antagonists; D000779:Anesthetics, Local; D010277:Parasympathomimetics; D014665:Vasodilator Agents
Untersuchungen in vitro-kultivierter Zellen glattmuskulärer Organe. 3. Die Beeinflussbarkeit der Pulsationsfrequenz isolierter glatter Muskelzellen des Hühneramnions durch Pharmaka