Conformation-dependent participation of the protein in electron equivalent transfer to cytochrome c.
When ferricytochrome c is reduced by H atoms (produced by pulse radiolysis) at neutral pH where it is in a closed protein configuration, a considerable percentage of the reduction proceeds through electron equivalent transfer via the protein. At pH 2.0, where cytochrome c is in an open configuration, H atoms reduce by adding directly to the heme porphyrin. The intermediate then observed is identified through similarity with that formed on ferriheme alone.
D003574:Cytochrome c Group / Q000378:metabolism*; D004579:Electron Transport; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D010084:Oxidation-Reduction; D011487:Protein Conformation; D013057:Spectrum Analysis; D013329:Structure-Activity Relationship
D003574:Cytochrome c Group