beta-lactamases in bacteroides.
Bacteroides fragilis is responsible for most anaerobic infections in man. Most isolates of B. fragilis show resistance to beta-lactam antibiotics. This resistance might be due to beta-lactamase production or permeability barrier in the cell wall. B. fragilis produce beta-lactamase with mainly cephalosporinase activity. Other Bacteroides species such as B. clostridiformis, B. melaninogenicus and B. oralis also produce beta-lactamase but with different biochemical characteristics.
D000581:Amidohydrolases / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001431:Bacteriological Techniques; D001439:Bacteroides / Q000201:enzymology*; D001442:Bacteroides Infections / Q000188:drug therapy*; D001441:Bacteroides fragilis / Q000201:enzymology; D002435:Cefamandole / Q000627:therapeutic use; D002440:Cefoxitin / Q000627:therapeutic use; D002473:Cell Wall / Q000201:enzymology; D002510:Cephalosporinase / Q000378:metabolism*; D002511:Cephalosporins / Q000627:therapeutic use*; D005663:Furans / Q000627:therapeutic use; D006801:Humans; D007525:Isoelectric Focusing; D010400:Penicillin G / Q000627:therapeutic use; D010403:Penicillin Resistance; D010405:Penicillinase / Q000378:metabolism*; D010406:Penicillins / Q000627:therapeutic use; D001443:Prevotella melaninogenica / Q000201:enzymology; D013045:Species Specificity; D047090:beta-Lactams / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D005663:Furans; D010406:Penicillins; D047090:beta-Lactams; D002435:Cefamandole; D002440:Cefoxitin; D000581:Amidohydrolases; D002510:Cephalosporinase; D010405:Penicillinase; D010400:Penicillin G