Induction of interferon in mice and cell cultures by Mycoplasma pneumoniae.
Inoculation of mice and L and human embryonic lung (HEL) cell cultures with Mycoplasma pneumoniae failed to induce the production of interferon. M. pneumoniae multiplied in these cell cultures without a marked cytopathic effect. M. pneumoniae induced interferon in human peripheral blood leukocytes with maximum titres of 32 units/ml at 48 hours after infection.
D000818:Animals; D002460:Cell Line; D006801:Humans; D007372:Interferons / Q000096:biosynthesis* / Q000097:blood; D007962:Leukocytes / Q000378:metabolism; D051379:Mice; D009174:Mycoplasma / Q000254:growth & development*; D009175:Mycoplasma Infections / Q000097:blood / Q000378:metabolism*; D009522:Newcastle disease virus / Q000254:growth & development
D007372:Interferons