Inhibition of gamma-glutamylcysteine synthetase by cystamine: an approach to a therapy of 5-oxoprolinuria (pyroglutamic aciduria).
D000592:Amino Acid Metabolism, Inborn Errors / Q000652:urine; D000818:Animals; D001921:Brain / Q000201:enzymology; D003538:Cystamine / Q000494:pharmacology*; D003543:Cysteamine / Q000494:pharmacology; D004220:Disulfides / Q000494:pharmacology; D005721:Glutamate-Cysteine Ligase / Q000037:antagonists & inhibitors*; D005971:Glutamates / Q000652:urine*; D006801:Humans; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D010453:Peptide Synthases / Q000037:antagonists & inhibitors*; D051381:Rats; D012756:Sheep; D013329:Structure-Activity Relationship; D005722:gamma-Glutamylcyclotransferase / Q000378:metabolism
D004220:Disulfides; D005971:Glutamates; D003543:Cysteamine; D005722:gamma-Glutamylcyclotransferase; D010453:Peptide Synthases; D005721:Glutamate-Cysteine Ligase; D003538:Cystamine