The effect of retinol and retinoic acid on the testicular phospholipase a activity in retinol-deficient rats.
Both phospholipases A1 and A2 activities (EC 3.1.1.4) at pH 7.4 were found to be significantly decreased in retinol-deficient rat testes supplemented with retinoic acid as compared to retinol-fed controls using 1-acyl-2-[1-(14)C]-oleoyl-sn-glycero-3-phosphocholine as substrate. However, little or no difference was observed in phospholipase A1 activity at pH 3.0 in both groups of rats.
D000818:Animals; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008297:Male; D010740:Phospholipases / Q000378:metabolism*; D051381:Rats; D013737:Testis / Q000187:drug effects / Q000201:enzymology*; D014212:Tretinoin / Q000378:metabolism*; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000494:pharmacology*; D014802:Vitamin A Deficiency
D014801:Vitamin A; D014212:Tretinoin; D010740:Phospholipases