Safety of therapy for allergic symptoms during pregnancy.
We undertook a literature review to document whether certain therapeutic measures could be considered safe during pregnancy in the allergic patient. With the possible exception of brompheniramine, the commonly used antihistamine drugs appear to be safe during pregnancy. The bronchodilators ephedrine and theophylline also appear to be safe, as does cromolyn. Corticosteroids do not appear to have adverse effects in pregnancy beyond those well recognized in nonpregnant patients. Because side effects are reduced when steroids are administered as aerosols in the nose or lung, these preparations seem well suited for use in pregnancy. The safety of allergic immunotherapy has been confirmed. For asthma, annual influenza vaccination is indicated.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D004205:Cromolyn Sodium / Q000009:adverse effects / Q000627:therapeutic use; D005100:Expectorants / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006634:Histamine H1 Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy*; D007167:Immunotherapy / Q000009:adverse effects; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D013566:Sympathomimetics / Q000009:adverse effects / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D005100:Expectorants; D006634:Histamine H1 Antagonists; D013566:Sympathomimetics; D004205:Cromolyn Sodium