High pK value of the N-terminal amino group of the gamma-chain causes low CO2 binding of human fetal hemoglobin.
D000595:Amino Acid Sequence; D002219:Carbamates / Q000097:blood; D002245:Carbon Dioxide / Q000097:blood*; D005319:Fetal Hemoglobin / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007526:Isoelectric Point; D007700:Kinetics; D010108:Oxyhemoglobins / Q000378:metabolism; D010455:Peptides / Q000378:metabolism; D013329:Structure-Activity Relationship
D002219:Carbamates; D010108:Oxyhemoglobins; D010455:Peptides; D002245:Carbon Dioxide; D005319:Fetal Hemoglobin