[Polygraphic recording of sleep under the influence of Plantival plus].
10 patients with moderate non-psychotic sleep disturbances were investigated polygraphically for a total of 14 nights each. These 14 nights were subdivided into 4 test series: Placebo was given during the first, Plantival plus during the second and third and placebo again during the fourth series. The results showed that wakefulness decreased after the application of Plantival plus and that there was an increase in deep sleep. These effects could be observed mainly during the first hour of sleep and disappeared gradually during the later sleeping hours. REM-phases were not influenced by the medication. Due to these observations, Plantival plus should mainly be applicated when disturbances in falling asleep and problems in sleeping continuously occur. In case interrupted sleep in the early morning hours has been found, this preparation could be applicated only in combination with other kinds of treatment.
D000328:Adult; D002986:Clinical Trials as Topic; D004155:Diphenhydramine / Q000494:pharmacology* / Q000627:therapeutic use; D004338:Drug Combinations; D004341:Drug Evaluation; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012890:Sleep / Q000187:drug effects*; D012894:Sleep Stages / Q000187:drug effects; D012893:Sleep Wake Disorders / Q000188:drug therapy*; D014508:Urea / Q000494:pharmacology* / Q000627:therapeutic use; D014851:Wakefulness / Q000187:drug effects
D004338:Drug Combinations; D010919:Placebos; D004155:Diphenhydramine; D014508:Urea
Polygraphische Registrierungen des Schlafes unter Wirkung von Plantival plus